Stem Cells

(The TQCC of Stem Cells is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
Stem cell homing: From physiology to therapeutics121
Pluripotent stem cell-derived retinal organoids for disease modeling and development of therapies81
Exosomal miRNA-17-5p derived from human umbilical cord mesenchymal stem cells improves ovarian function in premature ovarian insufficiency by regulating SIRT778
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy77
Vascularization of Human Brain Organoids61
Radiotherapy and the immune system: More than just immune suppression59
Signature quality attributes of CD146+ mesenchymal stem/stromal cells correlate with high therapeutic and secretory potency57
Macrophages at the Nexus of Mesenchymal Stromal Cell Potency: The Emerging Role of Chemokine Cooperativity54
N6-methyladenosine (m6A) RNA modification in cancer stem cells53
Mitochondrial Transfer from Mesenchymal Stem Cells to Macrophages Restricts Inflammation and Alleviates Kidney Injury in Diabetic Nephropathy Mice via PGC-1α Activation53
Wnt/β-catenin signaling is critical for regenerative potential of distal lung epithelial progenitor cells in homeostasis and emphysema46
Intranasal Delivery of Mesenchymal Stem Cells-Derived Extracellular Vesicles for the Treatment of Neurological Diseases42
Exosomes: Beyond stem cells for cardiac protection and repair42
Stem cell contributions to cementoblast differentiation in healthy periodontal ligament and periodontitis39
Mesenchymal stem cell immunomodulation: In pursuit of controlling COVID-19 related cytokine storm39
Exosome-educated macrophages and exosomes differentially improve ligament healing39
Human Induced Pluripotent Stem Cells: From Cell Origin, Genomic Stability, and Epigenetic Memory to Translational Medicine39
Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition38
Carcinoma-Associated Mesenchymal Stem/Stromal Cells: Architects of the Pro-tumorigenic Tumor Microenvironment37
Long noncoding RNA mediates stroke-induced neurogenesis36
Generation of hypoimmunogenic human pluripotent stem cells via expression of membrane-bound and secreted β2m-HLA-G fusion proteins35
Sox2 Controls Neural Stem Cell Self-Renewal Through a Fos-Centered Gene Regulatory Network34
Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells32
Extracellular vesicles derived from fibroblasts promote wound healing by optimizing fibroblast and endothelial cellular functions30
Characterization of Highly Proliferative Decidual Precursor Cells During the Window of Implantation in Human Endometrium30
Alternative splicing in mesenchymal stem cell differentiation29
Organoid Technology: Current Standing and Future Perspectives28
Mitochondria in Neurogenesis: Implications for Mitochondrial Diseases27
Gap Junction-Mediated Cell-Cell Interaction Between Transplanted Mesenchymal Stem Cells and Vascular Endothelium in Stroke26
Telomerase RNA processing: Implications for human health and disease26
Transplanted Pluripotent Stem Cell-Derived Photoreceptor Precursors Elicit Conventional and Unusual Light Responses in Mice With Advanced Retinal Degeneration26
miR-183/96/182 cluster is an important morphogenetic factor targeting PAX6 expression in differentiating human retinal organoids25
Signaling pathways essential for triple-negative breast cancer stem-like cells25
Restoring aged stem cell functionality: Current progress and future directions25
Canonical Notch signaling is required for bone morphogenetic protein-mediated human osteoblast differentiation25
Allogeneic adipose-derived stem cells promote ischemic muscle repair by inducing M2 macrophage polarization via the HIF-1α/IL-10 pathway24
Direct Neuronal Differentiation of Neural Stem Cells for Spinal Cord Injury Repair24
Human Induced Pluripotent Stem Cell-Derived Macrophages Ameliorate Liver Fibrosis23
Cancer Stem Cell-Targeted Therapeutic Approaches for Overcoming Trastuzumab Resistance in HER2-Positive Breast Cancer23
Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes23
The role of small extracellular vesicles in cerebral and myocardial ischemia—Molecular signals, treatment targets, and future clinical translation22
GATA6 regulates aging of human mesenchymal stem/stromal cells22
A human induced pluripotent stem cell-based modular platform to challenge sensorineural hearing loss21
Regulation of hippocampal postnatal and adult neurogenesis by adenosine A 2A receptor: Interaction with brain‐de21
Enteric mesenchymal cells support the growth of postnatal enteric neural stem cells21
Lineage-specific differentiation of osteogenic progenitors from pluripotent stem cells reveals the FGF1-RUNX2 association in neural crest-derived osteoprogenitors21
Zinc transporter 3 modulates cell proliferation and neuronal differentiation in the adult hippocampus21
Implantation of the clinical-grade human neural stem cell line, CTX0E03, rescues the behavioral and pathological deficits in the quinolinic acid-lesioned rodent model of Huntington's disease21
Human induced pluripotent stem cells and CRISPR/Cas-mediated targeted genome editing: Platforms to tackle sensorineural hearing loss20
Sars-Cov-2 Infects an Upper Airway Model Derived from Induced Pluripotent Stem Cells20
ABCB5+ Dermal Mesenchymal Stromal Cells with Favorable Skin Homing and Local Immunomodulation for Recessive Dystrophic Epidermolysis Bullosa Treatment20
Heat-stable enterotoxin inhibits intestinal stem cell expansion to disrupt the intestinal integrity by downregulating the Wnt/β-catenin pathway20
Mesenchymal stromal cells reprogram monocytes and macrophages with processing bodies19
On the road again: Establishment and maintenance of stemness in the neural crest from embryo to adulthood19
Characterization in Mice of the Resident Mesenchymal Niche Maintaining At2 Stem Cell Proliferation in Homeostasis and Disease19
Cell therapy in Huntington's disease: Taking stock of past studies to move the field forward19
Activation of β-catenin by TGF-β1 promotes ligament-fibroblastic differentiation and inhibits cementoblastic differentiation of human periodontal ligament cells18
Label-Free Quality Control and Identification of Human Keratinocyte Stem Cells by Deep Learning-Based Automated Cell Tracking18
NRL −/− gene edited human embryonic stem cells generate rod-deficient retinal organoids enriched in S-cone-like photoreceptors18
FZD5 regulates cellular senescence in human mesenchymal stem/stromal cells18
Metabolic Determinants of Cardiomyocyte Proliferation17
A genomic biomarker that identifies human bone marrow-derived mesenchymal stem cells with high scalability17
Combination therapy with Treg and mesenchymal stromal cells enhances potency and attenuation of inflammation after traumatic brain injury compared to monotherapy17
Cell cycle arrest and apoptosis are not dependent on p53 prior to p53-dependent embryonic stem cell differentiation17
Norepinephrine is a negative regulator of the adult periventricular neural stem cell niche17
Human Placenta Mesenchymal Stem Cell Protection in Ischemic Stroke is Angiotensin Converting Enzyme-2 and Masr Receptor-Dependent17
Potential applications of deep learning in single-cell RNA sequencing analysis for cell therapy and regenerative medicine16
Directed differentiation and direct reprogramming: Applying stem cell technologies to hearing research16
The Sca-1+ and Sca-1− mouse prostatic luminal cell lineages are independently sustained16
Increased Lipogenesis is Critical for Self-Renewal and Growth of Breast Cancer Stem Cells: Impact of Omega-3 Fatty Acids15
Fluid Shear Stress Promotes Embryonic Stem Cell Pluripotency via Interplay Between β-Catenin and Vinculin in Bioreactor Culture15
Neural Stem Cells in the Adult Olfactory Bulb Core Generate Mature Neurons in Vivo15
Generation of cerebral cortical GABAergic interneurons from pluripotent stem cells15
SALL1 regulates commitment of odontoblast lineages by interacting with RUNX2 to remodel open chromatin regions15
Mesenchymal Stem Cell-Derived Exosomes Ameliorate Diabetic Kidney Disease Through the NLRP3 Signaling Pathway15
Impaired Bone Fracture Healing in Type 2 Diabetes Is Caused by Defective Functions of Skeletal Progenitor Cells15
Trajectory mapping of human embryonic stem cell cardiogenesis reveals lineage branch points and an ISL1 progenitor-derived cardiac fibroblast lineage15
Histone demethylase KDM6A promotes somatic cell reprogramming by epigenetically regulating the PTEN and IL-6 signal pathways15
Mesenchymal Stem Cells Regulate Type 2 Innate Lymphoid Cells via Regulatory T Cells through ICOS-ICOSL Interaction15
Advancing physiological maturation in human induced pluripotent stem cell-derived cardiac muscle by gene editing an inducible adult troponin isoform switch15
Immunomodulatory and Regenerative Effects of MSC-Derived Extracellular Vesicles to Treat Acute GVHD14
Maintenance of Neural Stem-Progenitor Cells by the Lysosomal Biosynthesis Regulators TFEB and TFE3 in the Embryonic Mouse Telencephalon14
LncRNA, PLXDC2-OT Promoted the Osteogenesis Potentials of MSCs by Inhibiting the Deacetylation Function of RBM6/SIRT7 Complex and OSX Specific Isoform14
Electrophysiological Characterization of Photoreceptor-Like Cells in Human Inducible Pluripotent Stem Cell-Derived Retinal Organoids During in Vitro Maturation14
Oxidative Stress-induced Autophagy Compromises Stem Cell Viability14
Inflammatory Periodontal Ligament Stem Cells Drive M1 Macrophage Polarization via Exosomal miR-143-3p-Mediated Regulation of PI3K/AKT/NF-κB Signaling14
ELF3 Mediates IL-1α Induced Differentiation of Mesenchymal Stem Cells to Inflammatory iCAFs14
Impaired Hematopoietic Stem/Progenitor Cell Traffic and Multi-organ Damage in Diabetes13
A Synthetic mRNA Cell Reprogramming Method Using CYCLIN D1 Promotes DNA rEpair, Generating Improved Genetically Stable Human Induced Pluripotent Stem Cells13
Aryl Hydrocarbon Receptor Controls Skin Homeostasis, Regeneration, and Hair Follicle Cycling by Adjusting Epidermal Stem Cell Function13
Accelerated differentiation of human pluripotent stem cells into neural lineages via an early intermediate ectoderm population13
Mesenchymal Stromal Cell-Mediated Immune Regulation: A Promising Remedy in the Therapy of Type 2 Diabetes Mellitus13
MMP13 and TIMP1 are functional markers for two different potential modes of action by mesenchymal stem/stromal cells when treating osteoarthritis13
Improving hematopoietic engraftment: Potential role of mesenchymal stromal cell-derived extracellular vesicles13
Ubiquitous overexpression of CXCL12 confers radiation protection and enhances mobilization of hematopoietic stem and progenitor cells13
Multifaceted Involvement of Microglia in Gray Matter Pathology in Multiple Sclerosis13
Organoid Medicine for Inflammatory Bowel Disease12
Transient Receptor Potential Vanilloid 4 as a Regulator of Induced Pluripotent Stem Cell Chondrogenesis12
IGFBPs mediate IGF-1's functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to retinal organoids12
Gadd45g, A Novel Antidepressant Target, Mediates Metformin-Induced Neuronal Differentiation of Neural Stem Cells Via DNA Demethylation12
Pluripotent Stem Cells in Clinical Setting—New Developments and Overview of Current Status12
Neural Stem Cell-Derived Extracellular Vesicles Counteract Insulin Resistance-Induced Senescence of Neurogenic Niche12
Replicates in stem cell models—How complicated!11
Glioma stem cell (GSC)-derived autoschizis-like products confer GSC niche properties involving M1-like tumor-associated macrophages11
Single-cell profiling of long noncoding RNAs and their cell lineage commitment roles via RNA-DNA-DNA triplex formation in mammary epithelium11
Satellite cell activation and retention of muscle regenerative potential after long-term denervation11
Kappa opioid receptor controls neural stem cell differentiation via a miR-7a/Pax6 dependent pathway11
The opposing roles of the mTOR signaling pathway in different phases of human umbilical cord blood-derived CD34+ cell erythropoiesis11
Two DNA Binding Domains of MGA Act in Combination to Suppress Ectopic Activation of Meiosis-Related Genes in Mouse Embryonic Stem Cells11
Bone Marrow-Derived Progenitor Cells Contribute to Remodeling of the Postpartum Uterus11
Activation of estrogen receptor beta signaling reduces stemness of glioma stem cells11
Wnt Signaling in the Adult Hippocampal Neurogenic Niche11
ThemiR-200family is required for ectodermal organ development through the regulation of the epithelial stem cell niche11
Cell Cycle-Coupled Changes in the Level of Reactive Oxygen Species Support the Proliferation of Human Pluripotent Stem Cells10
The landscape of GPCR signaling in the regulation of epidermal stem cell fate and skin homeostasis10
Wnt5a Promotes AT1 and Represses AT2 Lineage-Specific Gene Expression in a Cell-Context-Dependent Manner10
CD44+ cells determine fenofibrate-induced microevolution of drug-resistance in prostate cancer cell populations10
Phage Display Targeting Identifies Eya1 as a Regulator of Glioblastoma Stem Cell Maintenance and Proliferation10
An Updated View of the Roles of p53 in Embryonic Stem Cells10
Toll-Like Receptor 5 Promotes the Neurogenesis From Embryonic Stem Cells and Adult Hippocampal Neural Stem Cells in Mice10
The Role of Lung Resident Mesenchymal Stromal Cells in the Pathogenesis and Repair of Chronic Lung Disease9
Bone-Forming Perivascular Cells: Cellular Heterogeneity and Use for Tissue Repair9
Regulation of ABO blood group antigen expression by miR-331-3p and miR-1908-5p during hematopoietic stem cell differentiation9
Overexpression of IGF-1 During Early Development Expands the Number of Mammary Stem Cells and Primes them for Transformation9
Enhanced collection of phenotypic and engrafting human cord blood hematopoietic stem cells at 4°C9
Expression levels and activation status of Yap splicing isoforms determine self-renewal and differentiation potential of embryonic stem cells9
A Case for Revisiting Nodal Signaling in Human Pluripotent Stem Cells9
The epitranscriptome landscape of small noncoding RNAs in stem cells9
Chemokine signaling is required for homeostatic and injury-induced neurogenesis in the olfactory epithelium9
Directly Reprogrammed Huntington's Disease Neural Precursor Cells Generate Striatal Neurons Exhibiting Aggregates and Impaired Neuronal Maturation9
State-Of-Play for Cellular Therapies in Cardiac Repair and Regeneration9
DNMT3B deficiency alters mitochondrial biogenesis and α-ketoglutarate levels in human embryonic stem cells9
SMAD-specific E3 ubiquitin ligase 2 promotes angiogenesis by facilitating PTX3 degradation in MSCs from patients with ankylosing spondylitis9
Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells9
Inhibition of O-GlcNAcase Inhibits Hematopoietic and Leukemic Stem Cell Self-Renewal and Drives Dendritic Cell Differentiation via STAT3/5 Signaling9
Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs9
Physioxia enhances T-cell development ex vivo from human hematopoietic stem and progenitor cells9
Adipose stem cell secretome markedly improves rodent heart and human induced pluripotent stem cell-derived cardiomyocyte recovery from cardioplegic transport solution exposure9
Intracellular matrix metalloproteinase-9 mediates epigenetic modifications and autophagy to regulate differentiation in human cardiac stem cells9