Stem Cells

Article	Citations
Correction to: Nicotinamide Riboside Modulates HIF-1 Signaling to Maintain and Enhance Odontoblastic Differentiation in Human Dental Pulp Stem Cells	81
TMEM16A regulates satellite cell-mediated skeletal muscle regeneration by ensuring a moderate level of caspase 3 activity	73
Human Retinal Ganglion Cells Respond to Evolutionarily Conserved Chemotropic Cues for Intra Retinal Guidance and Regeneration	51
The Role of Lung Resident Mesenchymal Stromal Cells in the Pathogenesis and Repair of Chronic Lung Disease	43
Erythropoietin-dependent acquisition of CD71hiCD105hi phenotype within CD235a− early erythroid progenitors	43
Vascular endothelial growth factor secretion and immunosuppression are distinct potency mechanisms of human bone marrow mesenchymal stromal cells	40
ZIC1 Dictates Osteogenesis Versus Adipogenesis in Human Mesenchymal Progenitor Cells Via a Hedgehog Dependent Mechanism	37
Very Small Embryonic-Like Stem Cells Transform Into Cancer Stem Cells and Are Novel Candidates for Detecting/Monitoring Cancer by a Simple Blood Test	36
Correction to: Melatonin-Primed MSCs Alleviate Intrauterine Adhesions by Affecting MSC-Expressed Galectin-3 on Macrophage Polarization	35
Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy	33
15-PGDH inhibition enhances hematopoietic regeneration during aging	30
Fisetin Attenuates Cellular Senescence Accumulation During Culture Expansion of Human Adipose-Derived Stem Cells	29
Effect of Hypoxia Preconditioning on the Regenerative Capacity of Adipose Tissue Derived Mesenchymal Stem Cells in a Model of Renal Artery Stenosis	29
HSC Niche Dynamics in Regeneration, Pre-malignancy, and Cancer: Insights From Mathematical Modeling	28
Exosomes derived from ADSC suppress endothelial cells ferroptosis and alleviate sepsis acute liver injury via regulation of Keap1/Nrf2/GPX4 axis	28
Neuroprotective Effects of Genome-Edited Human iPS Cell-Derived Neural Stem/Progenitor Cells on Traumatic Brain Injury	26
m6A mRNA demethylase FTO promotes chondrogenic differentiation of human bone marrow mesenchymal stem cells by targeting SMAD3	24
iPSC-Derived Airway Epithelial Cells: Progress, Promise, and Challenges	24
Hepatocyte growth factor facilitates the repair of spinal cord injuries by driving the chemotactic migration of mesenchymal stem cells through the β-catenin/TCF4/Nedd9 signaling pathway	23
Correction to: TGF-β secreted by human umbilical cord blood-derived mesenchymal stem cells ameliorates atopic dermatitis by inhibiting secretion of TNF-α and IgE	23
Reviewer Acknowledgment 2025	23
Linking mitochondria, fatty acids, and hematopoietic stem cell expansion during infection: implications for aging and metabolic diseases	22
Cohesin Subunit RAD21 Regulates the Differentiation and Self-Renewal of Hematopoietic Stem and Progenitor Cells	22
DNA hydroxy methylases Tet1 and Tet2 regulate bone aging and bone marrow stromal cell metabolism through the IGF-1/mTOR signaling axis	22
O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation	22

Highly efficient induction of Sox9 + scl-progenitors from embryonic stem cells for skeletal modeling	22
In Vitro Insights Into the Influence of Marrow Mesodermal/Mesenchymal Progenitor Cells on Acute Myelogenous Leukemia and Myelodysplastic Syndromes	21
Exosomes secreted from amniotic mesenchymal stem cells modify trophoblast activities by delivering miR-18a-5p and regulating HRK-p53 interaction	21
Metabolic Rewiring and Stemness: A Critical Attribute of Pancreatic Cancer Progression	21
Neural stem cell-derived extracellular vesicles alleviate inflammatory responses in a mouse model of atopic dermatitis	20
Application of Organoids in Regenerative Medicine	20
Lethal Phenotype-Based Database Screening Identifies Ceramide as a Negative Regulator of Primitive Streak Formation	20
Mesenchymal Stem/Stromal Cells Therapy for Metabolic Syndrome: Potential Clinical Application?	19
Manipulation of Signal Gradient and Transcription Factors Recapitulates: Multiple Hypothalamic Identities	19
Stromal STAT5-Mediated Trophic Activity Regulates Hematopoietic Niche Factors	19
Circadian timing optimizes allo-HSCT to prevent aGVHD: a breakthrough in chrono-immunotherapy	19
Comment on “critical role of the potential O-linked glycosylation sites of CXCR4 in cell migration and bone marrow homing of hematopoietic stem progenitor cells”	19
SARS-CoV2 infection triggers inflammatory conditions and astrogliosis-related gene expression in long-term human cortical organoids	18
Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells	18
Early Wnt Signaling Activation Promotes Inner Ear Differentiation via Cell Caudalization in Mouse Stem Cell-Derived Organoids	18
Enrichment of spermatogonial stem cells and staging of the testis cycle in a dasyurid marsupial, the fat-tailed dunnart	18
Prostaglandin E2 receptor EP2 is indispensable for maintenance of skeletal muscle stem cells	17
Opportunities with artificial intelligence in assessing the potency of mesenchymal stromal cells	17
FAM122A Is Required for Mesendodermal and Cardiac Differentiation of Embryonic Stem Cells	16
Transforming Growth Factor beta-2 (TGFβ2) Drives Trabecular Meshwork Progenitor Cell Differentiation Through SMAD2/3 Signalling	16
Expression of Concern: Combination of Systemic Chemotherapy with Local Stem Cell Delivered S-TRAIL in Resected Brain Tumors	16
Correction to: Division-Independent Differentiation of Muscle Stem Cells During a Growth Stimulus	16
Huntington’s disease human lateral ganglionic eminence precursors differentiate into functionally mature medium spiny neurons exhibiting pathology	16
Immunomodulatory and Regenerative Effects of MSC-Derived Extracellular Vesicles to Treat Acute GVHD	15
Stem cells within the HPA axis in tissue homeostasis and disease	15
Correction to: UBR2 Enriched in p53 Deficient Mouse Bone Marrow Mesenchymal Stem Cell-Exosome Promoted Gastric Cancer Progression via Wnt/β-Catenin Pathway	15
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Alleviate Hypoxia-Induced Pulmonary Arterial Hypertension in Mice Via Macrophages	15
Metabolic conditioning enhances human bmMSC therapy of doxorubicin-induced heart failure	15
Senescence accelerated mouse-prone 8: a model of neuroinflammation and aging with features of sporadic Alzheimer’s disease	15
Clinical evidence and critical review of mesenchymal stromal cells for corneal and ocular surface diseases	15
Molecular signature and regulatory network of human umbilical cord mesenchymal stromal cells as a niche for hematopoietic stem cells and progenitors	15
Microglia in the spinal cord stem cell niche regulate neural precursor cell proliferation via soluble CD40 in response to myelin basic protein	14
Timing of MeCP2 Expression Determines Midbrain Dopamine Neuron Phenotype Specification	14
Comment on “Changes in iPSC-Astrocyte Morphology Reflect Alzheimer’s Disease Patient Clinical Markers”	14
Bitter Taste Receptor Agonist Denatonium Inhibits Stemness Characteristics in Hematopoietic Stem/Progenitor Cells	14
Mesenchymal stromal cell therapy for scarring: a systematic review of clinical and preclinical studies	13
LARP7 enhances the potential of dental pulp stem cells to promote peripheral nerve repair	13
Extracellular vesicle microRNAs from human bone marrow MSCs suppress fibrogenesis of hepatic stellate cells by downregulation of RhoA signaling	13
Catechin promotes osteogenic differentiation via AMPK-mediated autophagy activation in bone marrow mesenchymal stem cells	13
Bone Marrow Mesenchymal Stem Cells-Derived miR-21-5p Protects Grafted Islets Against Apoptosis by Targeting PDCD4	13
Correction to: Cartilage Endplate Stem Cells Inhibit Intervertebral Disc Degeneration by Releasing Exosomes to Nucleus Pulposus Cells to Activate Akt/Autophagy	13
Transcriptomic analysis of the m6A reader YTHDF2 in the maintenance and differentiation of human embryonic stem cells	13
hucMSCs Treatment Ameliorated Pulmonary Fibrosis via Downregulating the circFOXP1-HuR-EZH2/STAT1/FOXK1 Autophagic Axis	12
DKK1 Activates the PI3K/AKT Pathway via CKAP4 to Balance the Inhibitory Effect on Wnt/β-Catenin Signaling and Regulates Wnt3a-Induced MSC Migration	12
Raman spectroscopies for cancer research and clinical applications: a focus on cancer stem cells	12
HucMSCs Delay Muscle Atrophy After Peripheral Nerve Injury Through Exosomes by Repressing Muscle-Specific Ubiquitin Ligases	12
Therapeutic potential of stem cell-derived extracellular vesicles in neurodegenerative diseases associated with cognitive decline	12
Stem cell and bioengineering approaches for end-stage renal disease: a comprehensive review	12
Mesenchymal stromal cell transplantation ameliorates fibrosis and microRNA dysregulation in skeletal muscle ischemia	12
Roles and Heterogeneity of Mesenchymal Progenitors in Muscle Homeostasis, Hypertrophy, and Disease	11

Brain pericytes derived from human pluripotent stem cells retain vascular and phagocytic functions under hypoxia	11
MSC-derived small extracellular vesicles promote dental pulp repair by alleviating inflammation in pulpitis via AKT and p38 MAPK pathways	11
Production and Limbal Lineage Commitment of Aniridia Patient-Derived Induced Pluripotent Stem Cells	11
In reply to the letter to the editor from Jin et al: critical insights into the role of miR-290 and miR-302 clusters in iPSC reprogramming	11
Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells	11
MSC-derived exosomal miR-125b-5p suppressed retinal microvascular endothelial cell ferroptosis in diabetic retinopathy	11
Newborn apical resection preserves the proliferative capacity of cardiomyocytes located throughout the left ventricle	11
BK Channel Depletion Promotes Adipocyte Differentiation by Activating the MAPK/ERK Pathway	11
Lineage Tracing of RGS5-CreER-Labeled Cells in Long Bones During Homeostasis and Injury	11
Establishment of vascularized human retinal organoids from induced pluripotent stem cells	11
Long noncoding RNA UCA1 promotes the chondrogenic differentiation of human bone marrow mesenchymal stem cells via regulating PARP1 ubiquitination	11
PDGFRα/Sca-1 Sorted Mesenchymal Stromal Cells Reduce Liver Injury in Murine Models of Hepatic Ischemia-Reperfusion Injury	11
Single-Cell RNA Sequencing Technology Landscape in 2023	10
Pdgfrβ marks distinct mesenchymal and pericyte populations within the periosteum with overlapping cellular features	10
Single-cell analysis of heterogeneity and molecular changes in cultured corneal epithelial stem cells during serial passage	10
Tibetan mesenchymal stem cell-derived exosomes alleviate pulmonary vascular remodeling in hypoxic pulmonary hypertension rats	10
Single-Cell RNA Sequencing ofSox17-Expressing Lineages Reveals Distinct Gene Regulatory Networks and Dynamic Developmental Trajectories	10
Human obesity decreases the anti-inflammatory functionality of adipose tissue–derived mesenchymal stem/stomal cells by upregulating IL-1β expression	10
Macrophage heterogeneity and plasticity in liver injury and repair mechanisms	9
Genetic ablation of p16 mitigates premature osteoporosis induced by PTHrP nuclear localization sequence and C-terminal deletion through inhibition of cellular senescence	9
NLRP3 deficiency improves bone healing of tooth extraction sockets through SMAD2/3-RUNX2-mediated osteoblast differentiation	9
Automated Generation of hiPSC-Derived Hepatic Progeny by Cost-Efficient Compounds	9
Stem cells enhance mitochondrial function in experimental Huntington’s disease	9
Valproic acid-expanded cord blood CD34+CD90+ cells are functionally distinct based on their origin	9
Efficacy of Whole Cancer Stem Cell-Based Vaccines: A Systematic Review of Preclinical and Clinical Studies	9
Isolation of an “Early” Transit Amplifying Keratinocyte Population in Human Epidermis: A Role for the Low Affinity Neurotrophin Receptor CD271	9
Stem cell specification and niche formation in developing incisor require actomyosin forces	8
Inflammatory pathways and the bone marrow microenvironment in inherited bone marrow failure syndromes	8
Silencing endomucin in bone marrow sinusoids improves hematopoietic stem and progenitor cell homing during transplantation	8
Derivation of functional early gestation decidual natural killer cell subtypes from induced pluripotent stem cells	8
Shaping the next era of stem cell science: a vision for stem cells journal and its global community	8
Synergizing Stem Cells with Biomaterials for Therapeutic Angiogenesis in Ischemic Diseases	8
Organoid-based personalized medicine: from tumor outcome prediction to autologous transplantation	8
Correction to: Combination of Systemic Chemotherapy with Local Stem Cell Delivered S-TRAIL in Resected Brain Tumors	8
Adult human heart extracellular matrix improves human iPSC-CM function via mitochondrial and metabolic maturation	8
Contribution of cytokeratin 19-expressing cells towards islet regeneration induced by multipotent stromal cell secreted proteins	8
Correction: Immunomodulatory Functions of Adipose Mesenchymal Stromal/Stem Cell Derived From Donors With Type 2 Diabetes and Obesity on CD4 T Cells	8
Chordin Like-1 Regulates Osteoblast and Adipocyte Differentiation Through Stabilizing Insulin-Like Growth Factor Binding Protein 3	8
Decoding the epigenetic and transcriptional basis of direct cardiac reprogramming	8
Mesenchymal stem cells derived EXO-miR3671 delivery promoted angiogenesis and accelerated wound healing of diabetes	8
The Characteristics and Survival Potential Under Sub-lethal Stress of Mesenchymal Stromal/Stem Cells Isolated from the Human Vascular Wall	8
Inhibition of O-GlcNAcase Inhibits Hematopoietic and Leukemic Stem Cell Self-Renewal and Drives Dendritic Cell Differentiation via STAT3/5 Signaling	8
Critical Role of miR-130b-5p in Cardiomyocyte Proliferation and Cardiac Repair in Mice After Myocardial Infarction	7
ETV2–ECSCR–mTOR pathways regulate reprogramming to the endothelial lineage	7
Mesenchymal Stem Cell-Derived Exosomes Ameliorate Diabetic Kidney Disease Through the NLRP3 Signaling Pathway	7
Critical insights into umbilical cord blood and tissue stem cells: navigating challenges to enhance clinical translation—a narrative review	7
Vacuolar protein sorting 4B is a novel regulator of osteoblast and adipocyte differentiation by activating autophagy signaling	7
Chemotherapy resistance of urinary bladder cancer mediated by a Notch and Wnt co-regulatory module of stemness	7
Human cortical neurons rapidly generated by embryonic stem cell programming integrate into the stroke-injured rat cortex	7
Transplantation of human stem cell-derived cone photoreceptors partially restores vision in aged rd1 mice with advanced retinal degeneration	7
“Quiescence” in the resting zone of the growth plate: a systematic review	7
Correction to: Basic Fibroblast Growth Factor Promotes Mesenchymal Stem Cell Migration by Regulating Glycolysis-Dependent β-Catenin Signaling	7
P21-Activated Kinase 4 Pak4 Maintains Embryonic Stem Cell Pluripotency via Akt Activation	7
Disease modeling of myocilin mutation-dependent normal tension glaucoma: human retinal ganglion cell susceptibility to unfolded protein response and mTOR signaling	7
From bench to bedside: stem and progenitor cell-derived extracellular vesicles in cardiac therapy	7
Long Noncoding RNA Lx8-SINE B2 Interacts with Eno1 to Regulate Self-Renewal and Metabolism of Embryonic Stem Cells	6
Advances in Stem Cell Immunotherapy	6
S-Adenosyl-l-Methionine Alleviates the Senescence of MSCs Through the PI3K/AKT/FOXO3a Signaling Pathway	6
Chd5 Regulates the Transcription Factor Six3 to Promote Neuronal Differentiation	6
The influence of biomimetic conditions on neurogenic and neuroprotective properties of dedifferentiated fat cells	6
Giant panda umbilical cord mesenchymal stem cell-derived exosomes promote dermal fibroblast proliferation and wound healing	6
Wnt/BMP Mediated Metabolic Reprogramming Preserves Multipotency of Neural Crest-Like Stem Cells	6
Hydrogen Sulfide Attenuates Mesenchymal Stem Cell Aging Progress via the Calcineurin-NFAT Signaling Pathway	6
Entropy Meets Physiology: Should We Translate Aging as Disorder?	6
Volume 42 Acknowledgments	6
Placenta-Derived Decidua Stromal Cells: A New Frontier in the Therapy of Acute Graft-Versus-Host Disease	6
Brent A. Reynolds, pioneer of adult neural stem cell biology	6
Human Umbilical Cord Mesenchymal Stem Cells Improve Lung Function in Chronic Obstructive Pulmonary Disease Rat Model Through Regulating Lung Microbiota	6
Conglomeration of T- and B-Cell Matrix Responses Determines the Potency of Human Bone Marrow Mesenchymal Stromal Cells	6
Serum Response Factor Reduces Gene Expression Noise and Confers Cell State Stability	6
Mesenchymal Stem Cells and Empagliflozin: a potential therapeutic approach for autophagy and Klotho modulation in Diabetic Kidney Disease	5
CircVapa promotes the abnormal differentiation of small intestinal epithelial stem cells in diabetic state	5
Revisiting the Mesenchymal “Stem vs. Stromal” Cell Dichotomy and Its Implications for Development of Improved Potency Metrics	5
Integrin-linked kinase control dental pulp stem cell senescence via the mTOR signaling pathway	5
Stem cell CNTF promotes olfactory epithelial neuroregeneration and functional recovery following injury	5
A mouse growth plate injury model identified contributions of Pdgfra and Pdgfrb cellular descendants to bo	5
Nephron progenitor fate is modulated by angiotensin type 1 receptor signaling in human kidney organoids	5
LSD1 Regulates Neurogenesis in Human Neural Stem Cells Through the Repression of Human-Enriched Extracellular Matrix and Cell Adhesion Genes	5
The Heterogeneous Cellular States of Glioblastoma Stem Cells Revealed by Single-Cell Analysis	5
Pulsed Electromagnetic Fields Combined With Adipose-Derived Stem Cells Protect Ischemic Myocardium by Regulating miR-20a-5p/E2F1/p73 Signaling	5

Correction to: Effects and Mechanism of Action of Neonatal Versus Adult Astrocytes on Neural Stem Cell Proliferation After Traumatic Brain Injury	5
Improved Cryopreservation of Human Induced Pluripotent Stem Cell (iPSC) and iPSC-derived Neurons Using Ice-Recrystallization Inhibitors	5
Loss of peroxisome function promotes oxidative stress-induced hematopoiesis	5
Cell barcoding reveals lineage-dependent outcomes in hiPSC cardiac differentiation	5
Subconjunctival Administration of Mesenchymal Stem Cells Alleviates Ocular Inflammation in a Murine Model of Corneal Alkali Burn	5
Single-cell transcriptome sequencing in synovial joint: insights of new progenitors and targets in joint development and disease	5
ETV2 Upregulation Marks the Specification of Early Cardiomyocytes and Endothelial Cells During Co-differentiation	5
Nicotinamide salvage is required for proliferation and sustaining self-renewal in undifferentiated embryonic stem cells	5
Exosomes released from immature neurons regulate adult neural stem cell differentiation through microRNA-7a-5p	5
Expression of Concern: Therapeutic Efficacy and Fate of Bimodal Engineered Stem Cells in Malignant Brain Tumors	4
Combination of 3 probiotics restores attenuated adult neurogenesis in germ-free mice	4
Enforced hematopoietic cell E-selectin/L-selectin ligand expression enhances bone marrow stromal cells homing and amelioration of cerebral ischemia-reperfusion injury via induction of prostaglandin E2	4
In Reply: Revisiting Claims of the Continued Absence of Functional Germline Stem Cells in Adult Ovaries	4
Single-cell RNA sequencing reveals vascularization-associated cell subpopulations in dental pulp: PDGFRβ+ DPSCs with activated PI3K/AKT pathway	4
The global evolution and impact of systems biology and artificial intelligence in stem cell research and therapeutics development: a scoping review	4
iPSC-derived modeling of HLA-lacking hematopoiesis reveals clonal diversity in eltrombopag response in acquired aplastic anemia	4
Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson’s disease	4
A p21 reporter iPSC line for evaluating CRISPR-Cas9 and vector-induced stress responses	4
Resistance to naive and formative pluripotency conversion in RSeT human embryonic stem cells	4
Vascularized Brain Assembloids With Enhanced Cellular Complexity Provide Insights Into the Cellular Deficits of Tauopathy	4
E-cigarettes Induce Dysregulation of Autophagy Leading to Endothelial Dysfunction in Pulmonary Arterial Hypertension	4
Modulation of WNT, Activin/Nodal, and MAPK Signaling Pathways Increases Arterial Hemogenic Endothelium and Hematopoietic Stem/Progenitor Cell Formation During Human iPSC Differentiation	4
Exosomes derived from bone marrow-derived mesenchymal stem cells of exercise-trained mice improve wound healing by inhibiting macrophage M1 polarization	4
Cellular therapies for the prevention and treatment of acute graft-versus-host disease	4
Critical insights into the role of miR-290 and miR-302 clusters in iPSC reprogramming	4
Bone marrow mononuclear cell transplantation promotes bone healing via gap junction-mediated cell–cell interaction	4
RSPO/LGR signaling regulates proliferation of adult hippocampal neural stem cells	4
Endogenous Bone Marrow-Derived Stem Cell Mobilization and Homing for In Situ Tissue Regeneration	4
Evaluation of stem-cell therapies in companion animal disease models: a concise review (2015-2023)	4