OOIR: Observatory of International Research

Papers

(The median citation count of Current Opinion in Hematology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
An update on the pathophysiology of immune thrombocytopenia	75
ANGPTL4: a multifunctional protein involved in metabolism and vascular homeostasis	72
Driver mutations in acute myeloid leukemia	41
IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies	40
Myeloid sarcoma	35
Effective use of hydroxyurea for sickle cell anemia in low-resource countries	33
The rebirth of the contact pathway: a new therapeutic target	31
Mechanisms of immunothrombosis in COVID-19	29
Structural organization of the bone marrow and its role in hematopoiesis	28
Brothers in arms: platelets and neutrophils in ischemic stroke	28
Clonal hematopoiesis driven by DNMT3A and TET2 mutations: role in monocyte and macrophage biology and atherosclerotic cardiovascular disease	27
The many flavors of monocyte/macrophage--endothelial cell interactions	27
Protection of hematopoietic stem cells from stress-induced exhaustion and aging	26
Erythrocyte adaptive metabolic reprogramming under physiological and pathological hypoxia	25
Blastic plasmacytoid dendritic cell neoplasm: diagnosis, manifestations, and treatment	25
Advances in chimeric antigen receptor T cells	23
Human babesiosis: recent advances and future challenges	22
The interaction between the complement system and hemostatic factors	20
Relapsed or primary refractory AML: moving past MEC and FLAG-ida	19
New insights into IVIg mechanisms and alternatives in autoimmune and inflammatory diseases	18
Optimal therapeutic strategies for mixed phenotype acute leukemia	17
Still a burning question: the interplay between inflammation and fibrosis in myeloproliferative neoplasms	17
Venetoclax combination therapy in acute myeloid leukemia and myelodysplastic syndromes	17
Update on the pathophysiology of transfusion-related acute lung injury	16
Biophysical and rheological biomarkers of red blood cell physiology and pathophysiology	15

Germline mutations in MDS/AML predisposition disorders	14
Chimeric antigen receptor T-cell therapy in acute myeloid leukemia	14
Hematopoietic stem cell regulation by the proteostasis network	14
The Nlrp3 inflammasome – the evolving story of its positive and negative effects on hematopoiesis	14
Role of complement in alloimmunization and hyperhemolysis	13
Vascular elastic fiber heterogeneity in health and disease	13
Small molecule therapeutics to treat the β-globinopathies	13
Systems analysis of hematopoiesis using single-cell lineage tracing	12
Single-cell fate decisions of bipotential hematopoietic progenitors	12
Recent advances in factor XII structure and function	12
Genetic heterogeneity and clonal evolution in acute myeloid leukemia	12
When basic science reaches into rational therapeutic design: from historical to novel leads for the treatment of β-globinopathies	11
GATA2 +9.5 enhancer: from principles of hematopoiesis to genetic diagnosis in precision medicine	11
An expanded role for dipeptidyl peptidase 4 in cell regulation	11
Symmetric and asymmetric activation of hematopoietic stem cells	11
Human hematopoiesis: aging and leukemogenic risk	10
The N6-methyladenosine RNA modification in acute myeloid leukemia	10
Role of chimeric antigen receptor T-cell therapy: bridge to transplantation or stand-alone therapy in pediatric acute lymphoblastic leukemia	10
Insights into ADAMTS13 structure: impact on thrombotic thrombocytopenic purpura diagnosis and management	10
Recent advances in allogeneic hematopoietic cell transplantation for acute myeloid leukemia	9
Current understanding of human megakaryocytic-erythroid progenitors and their fate determinants	9
Prothrombotic state associated with preeclampsia	9
Mouse models of vascular development and disease	9
Ineffective erythropoiesis in sickle cell disease: new insights and future implications	9
Protein S: function, regulation, and clinical perspectives	8
Measurement of tissue factor-positive extracellular vesicles in plasma: strengths and weaknesses of current methods	8
The congenital dyserythropoieitic anemias: genetics and pathophysiology	8
The protein C pathways	8
Current and future gene therapies for hemoglobinopathies	8
Targeting the cluster of differentiation 47/signal-regulatory protein alpha axis in myeloid malignancies	8
A zebrafish toolbox for biomechanical signaling in cardiovascular development and disease	7
Immunomodulatory roles of red blood cells	7
Complement contributions to COVID-19	7
Regulation and importance of factor VIII levels in hemophilia A carriers	7
Casting a NET on cancer: the multiple roles for neutrophil extracellular traps in cancer	7
Cellular components of the hematopoietic niche and their regulation of hematopoietic stem cell function	7
Emerging therapeutic and preventive approaches to transplant-associated thrombotic microangiopathy	7
In-vivo differentiation of adult hematopoietic stem cells from a single-cell point of view	6
Hormetic endoplasmic reticulum stress in hematopoietic stem cells	6
Umbilical cord blood: an undervalued and underutilized resource in allogeneic hematopoietic stem cell transplant and novel cell therapy applications	6
Podosomes in endothelial cell--microenvironment interactions	6
Regulation of stress-induced hematopoiesis	6
Clonal hematopoiesis in hematopoietic stem cell transplantation	6
Translational control by heme-regulated elF2α kinase during erythropoiesis	6
Heterogeneity of fetal hemoglobin production in adult red blood cells	6
PIEZO1, sensing the touch during erythropoiesis	6
Blood in the water: recent uses of zebrafish to study myeloid biology	6
Thrombosis in myeloproliferative neoplasms: update in pathophysiology	6
Detection and management of acute myeloid leukemia measurable residual disease: is it standard of care?	6
Tumor protein 53 mutations in acute myeloid leukemia: conventional induction chemotherapy or novel therapeutics	6

How haematopoiesis research became a fertile ground for regulatory network biology as pioneered by Eric Davidson	5
Novel concepts in red blood cell clearance	5
Therapeutic approaches targeting splicing factor mutations in myelodysplastic syndromes and acute myeloid leukemia	5
Studying clonal evolution of myeloid malignancies using induced pluripotent stem cells	5
Hepcidin mimetics in polycythemia vera: resolving the irony of iron deficiency and erythrocytosis	5
VEXAS: where do we stand 2 years later?	5
Enhancing cardiovascular research with whole-organ imaging	5
Proteomic/transcriptomic analysis of erythropoiesis	5
Alteration of interleukin-10-producing Type 1 regulatory cells in autoimmune diseases	5
The significance of CUX1 and chromosome 7 in myeloid malignancies	5
Hematopoietic regeneration under the spell of epigenetic-epitranscriptomic factors and transposable elements	5
Significance and management of isolated distal deep vein thrombosis	5
Optimizing leukapheresis product yield and purity for blood cell-based gene and immune effector cell therapy	5
Deciphering transcriptional and functional heterogeneity in hematopoiesis with single-cell genomics	5
Immunologic effects of red blood cell and platelet transfusions in neonates	5
Platelet transfusion for patients with platelet dysfunction: effectiveness, mechanisms, and unanswered questions	5
Distinguishing atypical chronic myeloid leukemia from other Philadelphia-negative chronic myeloproliferative neoplasms	5
Congenital neutropenia: disease models guiding new treatment strategies	4
Clinical experience of coronavirus disease 2019 in hematopoietic cell transplant and chimeric antigen receptor T-cell recipients	4
Heterogeneity and origins of myeloid cells	4
Erythroid cells and malaria parasites: it's a match!	4
Novel therapies in myelodysplastic syndromes	4
The role of biomarkers in risk stratification, treatment and outcome in acute GVHD	4
Diverse functions of long noncoding RNAs in acute myeloid leukemia: emerging roles in pathophysiology, prognosis, and treatment resistance	4
Maintenance therapy for acute myeloid leukemia: sustaining the pursuit for sustained remission	3
Erythrocyte pyruvate kinase activation in red cell disorders	3
Clonal hematopoiesis and myeloid malignancies: clonal dynamics and clinical implications	3
The invisible string of coagulation, complement, iron, and inflammation in sickle cell disease	3
Methods to quantify endothelial cell front-rear polarity in vivo and in vitro	3
Update in clinical and mouse microbiota research in allogeneic haematopoietic cell transplantation	3
Clinical trials for chimeric antigen receptor T-cell therapy: lessons learned and future directions	3
Role of p53 in regulation of hematopoiesis in health and disease	3
Hypomethylating agents with venetoclax: have we discovered the holy grail?	3
Single-cell RNA sequencing to study vascular diversity and function	3
Novel immune directed therapies in myelodysplastic syndromes and acute myeloid leukemia	3
Venous thromboembolism in the hormonal milieu	3
Azacitidine maintenance in AML post induction and posttransplant	3
Updates in diagnosis of the inherited platelet disorders	3
Role of ATP-dependent chromatin remodelers in hematopoietic stem and progenitor cell maintenance	3
Global perspectives on cellular therapy for children with sickle cell disease	3