Experimental and Clinical Psychopharmacology

Papers
(The median citation count of Experimental and Clinical Psychopharmacology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Cognitive outcomes associated with long-term, regular, recreational cannabis use in adults: A meta-analysis.47
Effects of electronic cigarette heating coil resistance and liquid nicotine concentration on user nicotine delivery, heart rate, subjective effects, puff topography, and liquid consumption.30
Behavioral economics of substance use: Understanding and reducing harmful use during the COVID-19 pandemic.29
Drug checking at dance festivals: A review with recommendations to increase generalizability of findings.27
Pharmacological validation of a translational model of cocaine use disorder: Effects of d-amphetamine maintenance on choice between intravenous cocaine and a nondrug alternative in humans and rhesus m25
Setting a goal could help you control: Comparing the effect of health goal versus general episodic future thinking on health behaviors among cigarette smokers and obese individuals.24
A preliminary test of a brief intervention to lessen young adults’ cannabis use: Episode-level smartphone data highlights the role of protective behavioral strategies and exercise.23
Effects of Δ⁹-tetrahydrocannabinol (THC) vapor inhalation in Sprague-Dawley and Wistar rats.22
Cigarette smoke-induced alterations in blood: A review of research on DNA methylation and gene expression.22
Behavioral economic measurement of cigarette demand: A descriptive review of published approaches to the cigarette purchase task.22
No pain, all gain? Interim analyses from a longitudinal, observational study examining the impact of medical cannabis treatment on chronic pain and related symptoms.22
A multisample demonstration of using the prolific platform for repeated assessment and psychometric substance use research.21
Social, psychological, and substance use characteristics of U.S. adults who use kratom: Initial findings from an online, crowdsourced study.20
A comprehensive review of measures of protective behavioral strategies across various risk factors and associated PBS-related interventions.19
Sleep disturbance as a therapeutic target to improve opioid use disorder treatment.19
Attitudes toward opioid use disorder medications: Results from a U.S. national study of individuals who resolved a substance use problem.18
Episodic future thinking as a brief alcohol intervention for heavy drinking college students: A pilot feasibility study.17
The N-methyl-D-aspartate receptor antagonist d-methadone acutely improves depressive-like behavior in the forced swim test performance of rats.17
Behavioral economic demand as a unifying language for addiction science: Promoting collaboration and integration of animal and human models.16
Establishing preclinical withdrawal syndrome symptomatology following heroin self-administration in male and female rats.16
The validity of qualtrics panel data for research on video gaming and gaming disorder.15
Sexual discounting: A systematic review of discounting processes and sexual behavior.15
Contextual influences on subjective alcohol response.14
Evaluating and improving the quality of survey data from panel and crowd-sourced samples: A practical guide for psychological research.14
A systematic review and meta-analysis of delay discounting and cannabis use.14
Delay and probability discounting in cocaine use disorder: Comprehensive examination of money, cocaine, and health outcomes using gains and losses at multiple magnitudes.13
Future thinking to decrease real-world drinking in alcohol use disorder: Repairing reinforcer pathology in a randomized proof-of-concept trial.13
Longitudinal associations between negative urgency, symptoms of depression, cannabis and alcohol use in veterans.13
Conditioned enhancement of the nicotine reinforcer.13
Risk factors associated with alcohol and drug use among bisexual women: A literature review.13
Deep brain stimulation of the nucleus accumbens/ventral capsule for severe and intractable opioid and benzodiazepine use disorder.12
Dual use of alcohol and cannabis among college students: A reinforcer pathologies approach.12
On-line personalized feedback intervention for negative affect and cannabis: A pilot randomized controlled trial.12
The effects of cannabidiol and analgesic expectancies on experimental pain reactivity in healthy adults: A balanced placebo design trial.12
Influence of menthol and green apple e-liquids containing different nicotine concentrations among youth e-cigarette users.12
Randomized controlled trial of motivational interviewing for alcohol and cannabis use within a predominantly Hispanic adolescent sample.12
Ethnoracial health disparities and the ethnopsychopharmacology of psychedelic-assisted psychotherapies.12
Are poor quality data just random responses?: A crowdsourced study of delay discounting in alcohol use disorder.11
Increasing cessation motivation and treatment engagement among smokers in pain: A pilot randomized controlled trial.11
Careless responding in crowdsourced alcohol research: A systematic review and meta-analysis of practices and prevalence.11
Smokers with pain are more likely to report use of e-cigarettes and other nicotine products.11
Context and craving among individuals with alcohol use disorder attempting to moderate their drinking.10
Examining the heterogeneity of polysubstance use patterns in young adulthood by age and college attendance.10
Diversity inclusion in United States opioid pharmacological treatment trials: A systematic review.10
Resurgence of punishment-suppressed cocaine seeking in rats.10
What about this time? Within- and between-person associations between drinking motives and alcohol outcomes.10
Pharmacogenetics and therapeutic drug monitoring of fluoxetine in a real-world setting: A PK/PD analysis of the influence of (non-)genetic factors.10
Integrated cognitive-behavioral therapy for comorbid cannabis use and anxiety disorders: The impact of severity of cannabis use.9
Minority stress and alcohol use in sexual minority women’s daily lives.9
The effects of artificially induced proestrus on heroin intake: A critical role for estradiol.9
Further validation of the Treatment Self-Regulation Questionnaire for assessing motivations for responsible drinking: A test of self-determination theory.9
Behavioral economics and coping-related drinking motives in trauma exposed drinkers: Implications for the self-medication hypothesis.9
The importance of psychology for shaping legal cannabis regulation.8
Reducing tobacco use among women of childbearing age: Contributions of tobacco regulatory science and tobacco control.8
The prospective interactive effects of alcohol expectancies and subjective response on future drinking behavior.8
Predicting college student prescription stimulant misuse: An analysis from ecological momentary assessment.8
The role of substance use coping in linking depression and alcohol use from late adolescence through early adulthood.8
Cannabis use, cognitive performance, and symptoms of attention deficit/hyperactivity disorder in community adults.8
Predicting adverse consequences of alcohol consumption in underage college students using a novel Fake ID Purchase Task.8
Narrative theory III: Evolutionary narratives addressing mating motives change discounting and tobacco valuation.8
The behavioral economics of the bottomless cup: The effects of alcohol cup price on consumption in college students.8
Randomized controlled trial of d-cycloserine in cocaine dependence: Effects on contingency management and cue-induced cocaine craving in a naturalistic setting.7
Strain and sex matters: Differences in nicotine self-administration between outbred and recombinase-driver transgenic rat lines.7
Using social network methodology to examine the effects of exposure to alcohol-related social media content on alcohol use: A critical review.7
Methamphetamine administration dose effects on sexual desire, sexual decision making, and delay discounting.7
Use patterns, beliefs, experiences, and behavioral economic demand of indica and sativa cannabis: A cross-sectional survey of cannabis users.7
Young adults’ beliefs about modern oral nicotine products: Implications for uptake in nonvapers, dual use with e-cigarettes, and use to reduce/quit vaping.7
A pilot randomized controlled trial of smartphone-assisted mindfulness-based intervention with contingency management for smokers with mood disorders.7
Behavioral economic demand for medications and its relation to clinical measures in multiple sclerosis.7
Tobacco-use behavior and toxicant exposure among current dual users of electronic cigarettes and tobacco cigarettes.7
Remotely administered incentive-based treatment for alcohol use disorder with participant-funded incentives is effective but less accessible to low-income participants.7
A crowdsourcing survey study on the subjective effects of delta-8-tetrahydrocannabinol relative to delta-9-tetrahydrocannabinol and cannabidiol.7
Examining associations between impulsivity, opioid use disorder, and posttraumatic stress disorder: The additive relation between disorders.7
Baseline performance moderates stimulant effects on cognition in youth with ADHD.7
The feasibility, acceptability, and initial efficacy of a remotely delivered, financial-incentive intervention to initiate vaping abstinence in young adults.6
Sleep moderates the relationship between stress and craving in individuals with opioid use disorder.6
A multimethod investigation of distress tolerance and problematic alcohol use.6
Using a dependent schedule to measure risky choice in male rats: Effects of d-amphetamine, methylphenidate, and methamphetamine.6
Wireless electroencephalography (EEG) to monitor sleep among patients being withdrawn from opioids: Evidence of feasibility and utility.6
Dual study describing patient-driven harm reduction goal-setting among people experiencing homelessness and alcohol use disorder.6
Pilot feasibility trial of dual contingency management for cigarette smoking cessation and weight maintenance among weight-concerned female smokers.6
Effect of the glucocorticoid receptor antagonist PT150 on acquisition and escalation of fentanyl self-administration following early-life stress.6
Beyond online participant crowdsourcing: The benefits and opportunities of big team addiction science.6
Investigating tobacco withdrawal in response to reduced nicotine cigarettes among smokers with opioid use disorder and other vulnerabilities.6
The phenotype of recovery II: The association between delay discounting, self-reported quality of life, and remission status among individuals in recovery from substance use disorders.6
Anxiety sensitivity and opioid use motives among adults with chronic low back pain.6
Refining the marijuana purchase task: Using qualitative methods to inform measure development.6
Motivational pathways to problematic drinking among Latinx college drinkers.6
Alcohol craving in the natural environment: Moderating roles of cue exposure, drinking, and alcohol sensitivity.6
Female drinkers are more sensitive than male drinkers to alcohol-induced heart rate increase.6
Differential effects of UPPS-P impulsivity on subjective alcohol response and craving: An experimental test of acquired preparedness.6
BDNF association study with obsessive–compulsive disorder, its clinical characteristics, and response to fluvoxamine-treatment in Iranian patients.6
Impulsivity and the effects of alcohol in women with a history of childhood sexual abuse: A pilot study.6
Caffeine enhances sustained attention among adolescents.6
“Buzzwords”: Crowd-sourcing and quantifying U.S. young adult terminology for subjective effects of alcohol and marijuana use.5
The effects of inhaled flavors on intravenous nicotine.5
Are trait impulsivity and exposure to cannabis or alcohol associated with the age of trajectory of cocaine use? A gender-specific dimensional analysis in humans with cocaine dependence diagnosis.5
Discounting of delayed monetary and cannabis rewards in a crowdsourced sample of adults.5
Affect and drinking behavior: Moderating effects of involuntary attention to emotion and distress tolerance.5
Precision medicine in alcohol use disorder: Mapping etiologic and maintenance mechanisms to mechanisms of behavior change to improve patient outcomes.5
Virtual grocery shopping and cookie consumption following intranasal insulin or placebo application.5
Electrophysiological responses to emotional and cocaine cues reveal individual neuroaffective profiles in cocaine users.5
Sex-dependent effects of alcohol administration on the urge to use cannabis.5
Effects of two kinds of noradrenergic ADHD medicines on sign-tracking and goal-tracking in male rats.5
DUI offenders display reduced perception of intoxication and heightened impulsive choice in response to alcohol.5
Generalizability and representativeness: Considerations for internet-based research on substance use behaviors.5
Correlates of tobacco use among Asian and Pacific Islander youth and young adults in the U.S.: A systematic review of the literature.5
Why adolescents engage in early alcohol use: A study of drinking motives.5
Posttraumatic stress as a moderator of the association between HPA-axis functioning and alcohol use disorder among a community sample of women currently experiencing intimate partner violence.5
Ad libitum high fat diet consumption during adolescence and adulthood fails to impact the affective properties of cocaine in male Sprague-Dawley rats.5
An optimized procedure for robust volitional cocaine intake in mice.5
Individual differences in biological regulation: Predicting vulnerability to drug addiction, obesity, and other dysregulatory disorders.5
Behavioral economic interactions between cannabis and alcohol purchasing: Associations with disordered use.5
Dimensions of binegativity differentially predict drinking to cope motivations and alcohol use severity among bisexual women.5
Diversity inclusion in clinical trials investigating esketamine for depression: A systematic review.5
Correlations of kratom (Mitragyna speciosa Korth.) use behavior and psychiatric conditions from a cross-sectional survey.5
Opioid-enhancing antinociceptive effects of delta-9-tetrahydrocannabinol and amitriptyline in rhesus macaques.5
Effects of combining alcohol and cannabis on driving, breath alcohol level, blood THC, cognition, and subjective effects: A narrative review.4
Using crowdsourcing to study the differential effects of cross-drug withdrawal for cigarettes and opioids in a behavioral economic demand framework.4
Alcohol use and related consequences for monoracial and multiracial Native American/American Indian college students.4
Association of SAPAP3 allelic variants with symptom dimensions and pharmacological treatment response in obsessive–compulsive disorder.4
An evaluation of the effect of methylphenidate on working memory, time perception, and choice impulsivity in children with ADHD.4
Examining the effects of implicit and explicit racial identity on psychological distress and substance use among Black young adults.4
Differences in serum orexin-A levels between the acute and subacute withdrawal phases in individuals who use methamphetamine.4
Organization and activation of alcohol expectancies across empirically derived profiles of college student drinkers.4
Appeal, subjective effects, and relative reinforcing effects of JUUL that vary in flavor and nicotine content.4
The language of subjective alcohol effects: Do young adults vary in their feelings of intoxication?4
Pilot trial of QuitBet: A digital social game that pays you to stop smoking.4
The discounting of death: Probability discounting of heroin use by fatal overdose likelihood and drug purity.4
Initial evaluation of domain-specific episodic future thinking on delay discounting and cannabis use.4
Intranasal racemic ketamine for patients hospitalized with treatment-resistant depression: A retrospective analysis.4
Pain and alcohol consumption in virtual reality.4
Reduced expression of ethanol sensitization by α3β4 nicotinic acetylcholine receptors in DBA/2J mice.4
A reinforcer pathology approach to cannabis misuse: Evaluation of independent and interactive roles of cannabis demand and delay discounting in a sample of community adults.4
Self-Reported Symptoms of Cannabis Use Disorder: Psychometric testing and validation.4
Measurement of cigarette smoking: Comparisons of global self-report, returned cigarette filters, and ecological momentary assessment.4
Affect and alcohol consumption: An ecological momentary assessment study during national lockdown.4
Association of SLC1A1 gene polymorphism with obsessive compulsive disorder in a sample from southern India.4
A comprehensive examination of alcohol-related motivations among college students: Unique relations of drinking motives and motivations for drinking responsibly.4
Crowdsourcing methods in addiction science: Emerging research and best practices.3
Effects of chronic treatment with bupropion on self-administration of nicotine + cocaine mixtures in nonhuman primates.3
Abuse liability of electronic cigarettes in men who are experienced electronic cigarette users.3
Characterizing the reinforcing value of tobacco using a cigarette purchase task: An item response theory approach.3
The interactive effects of JUUL flavor and nicotine concentration on addiction potential.3
Discrimination, psychological functioning, and substance use among U.S. young adults aged 18–28, 2017.3
Automated assessment of alcohol-induced impairment of balance in male and female social drinkers.3
Compounded intranasal racemic ketamine for major depressive disorder: A case report.3
A systematic review and meta-analysis of interventions to induce attempts to quit tobacco among adults not ready to quit.3
The cultural equivalence of measurement in substance use research.3
An evaluation of fixed and randomized price sequence on the alcohol purchase task.3
Examining the relationship between substance use and exploration–exploitation behavior in young adults.3
Expectation for stimulant type modifies caffeine’s effects on mood and cognition among college students.3
One-year predictions of delayed reward discounting in the adolescent brain cognitive development study.3
Psychometric validation of the Protective Drinking Practices Scale in college students across the United States.3
Reinforcer pathology of internet-related behaviors among college students: Data from six countries.3
Promoting harm reduction as a treatment outcome in substance use disorders.3
Higher olfactory sensitivity to coffee odour in habitual caffeine users.3
Twenty-first birthday drinking: Extreme-drinking episodes and white matter microstructural changes in the fornix and corpus callosum.3
A comprehensive examination of motivational profiles for alcohol-related behaviors among college students.3
Verbal behavior related to drug reinforcement in polysubstance cannabis users: Comparison across drugs.3
Understanding data quality: Instructional comprehension as a practical metric in crowdsourced investigations of behavioral economic cigarette demand.3
Prescription drug and alcohol simultaneous co-ingestion in U.S. young adults: Prevalence and correlates.3
Effects of oral Δ9-tetrahydrocannabinol and cannabidiol combinations on a sustained attention task in rats.3
Effort-related decision making and cannabis use among college students.3
The effect of acute nicotine administration on human delay cued and context fear conditioning.3
Cumulative disadvantage as a framework for understanding rural tobacco use disparities.3
Perinatal use of lurasidone for the treatment of bipolar disorder.3
Can exercise alleviate sleep disturbances during acute nicotine withdrawal in cigarette smokers?3
Using alcohol biosensors and biomarkers to measure changes in drinking: Associations between transdermal alcohol concentration, phosphatidylethanol, and self-report in a contingency management study o3
Online personalized feedback intervention reduces cannabis-related problems among college students with high problem distress.3
Changes in affect and alcohol craving during naturally occurring drinking episodes: The role of day-level drinking motives.3
A model of reinforcement sensitivity, impulsivity, alcohol use, and risky sexual behavior in a sample of young adult drinkers.3
Differences in cannabis use characteristics, routines, and reasons for use among individuals with and without a medical cannabis card.3
Characterizing different-flavored e-cigarette solutions from user-reported sensory attributes and appeal.3
The interaction of nicotine concentration and device power on electronic nicotine delivery system (ENDS) abuse liability among exclusive ENDS users and dual users of ENDS and combustible cigarettes.3
Nuanced relations between simultaneous alcohol and cannabis use motives and negative consequences among college students: The role of multiple product use.3
Statistically derived patterns of behavioral economic risk among heavy-drinking college students: A latent profile analysis.3
Physical activity reduces alcohol consumption induced by reward downshift.2
Pain interference and cognitive processes of e-cigarette use: The differential effect of sex.2
PKC inhibition decreases amphetamine-maintained responding under a progressive-ratio schedule of reinforcement.2
Xylazine suppresses fentanyl consumption during self-administration and induces a unique sex-specific withdrawal syndrome that is not altered by naloxone in rats.2
Delay discounting and neurocognitive performance in young adults with differential patterns of substance use: Findings from the Human Connectome Project.2
Pathways linking ethnic discrimination and drug-using peer affiliation to underage drinking status among Mexican-origin adolescents.2
Novel methods for the remote investigation of emerging substances: Application to kratom.2
Effect of cannabinoids on brain metabolites: A review of animal and human studies.2
External validity of analogue sexual risk laboratory data.2
Harmine impairs memory performance of treated rats and nontreated cagemates.2
Cross-substance primed and cue-induced craving among alcohol and cannabis co-users: An experimental psychopharmacology approach.2
Sex differences in associations between delay discounting and expectancies for alcohol analgesia.2
Interactive effects of protonated nicotine concentration and device power on ENDS nicotine delivery, puff topography, and subjective effects.2
Changing the paradigm in treatment-resistant depression: A review of long-term efficacy and tolerability of esketamine nasal spray.2
The effect of area-level disadvantage and race on smoking abstinence in a clinical trial.2
Working memory and alcohol demand relationships differ according to PTSD symptom severity among veterans with AUD.2
Impact of smoked cannabis on tobacco cigarette smoking intensity and subjective effects: A placebo-controlled, double-blind, within-subjects human laboratory study.2
Bidirectional influence of heroin and cocaine escalation in persons with dual opioid and cocaine dependence diagnoses.2
Cannabis and emotion processing: A review of behavioral, physiological, and neural responses.2
Using the Cigarette Purchase Task to examine the relative reinforcing value of cigarettes among mothers with versus without opioid dependence.2
Integration of motivational interviewing and behavioral economic theories to enhance brief alcohol interventions: Rationale and preliminary examination of client language.2
Recent alcohol-induced blackouts among heavy drinking college students: A qualitative examination of intentions, willingness, and social context.2
Chronic pain and COVID-19: The association of delay discounting with perceived stress and pain severity.2
The acute dose and baseline amplitude-dependent effects of CDP-choline on deviance detection (MMN) in chronic schizophrenia: A pilot study.2
Binding potential changes of SERT in patients with depression are associated with remission: A prospective [¹²³I]β-CIT-SPECT study.2
Successful substance use disorder recovery in transitional housing: Perspectives from African American women.2
Pregestational oxycodone exposure does not impact future maternal care or drug preference in the postpartum mouse.2
Interest in and perceived effectiveness of contingency management among alcohol drinkers using behavioral economic purchase tasks.2
Behavioral economic assessment of abuse liability for Black & Mild cigar flavors among young adults.2
Effects of substance use on monetary delay discounting among people who use stimulants with and without HIV: An ecological momentary assessment study.2
Narrative theory IV: Within-subject effects of active and control scarcity narratives on delay discounting in alcohol use disorder.2
Ethanol induces a dose-dependent conditioned place preference and conditioned place aversion in Japanese quail.2
Sources for prescription stimulant misuse: A person-centered approach to understanding links to substance use and psychiatric impairment.2
A psychometric evaluation of the Marijuana Problems Index among college students: Confirmatory factor analysis and measurement invariance by gender.2
A mobile phone–based brief intervention with personalized feedback and interactive text messaging is associated with changes in driving after cannabis use cognitions in a proof-of-concept pilot trial.2
Insights into the context of simultaneous alcohol and cannabis use among young adults.2
Utility of a brief assessment of opioid demand among post-discharge trauma care patients.2
Assessment of demand for methamphetamine and cigarettes among individuals with methamphetamine use disorder.2
Incorporating socioeconomic status into studies on delay discounting and health via subjective financial status: An initial validation in tobacco use.2
Acceptability and feasibility of incorporating contingency management into a public treatment program for homeless crack cocaine users in Brazil: A pilot study.2
Persisting on the past: Cross-sectional and prospective associations between sunk cost propensity and cannabis use.2
Reliability of an adaptive marijuana purchase task.2
Heightened sensitivity to the disinhibiting effect of alcohol in women during the late follicular phase of the menstrual cycle.2
Impact of fluoxetine preexposure on MDMA-induced taste avoidance in male and female rats.2
Both reducing cigarettes per day and transitioning to very low-nicotine-content cigarettes decreases demand for usual-brand cigarettes.2
Feasibility, tolerability, and potential advantages of a dyadic financial incentive treatment for smoking cessation among dual-smoker couples: A pilot study.2
Influence of personality on acute smoked cannabis effects on simulated driving.2
Cannabis craving in response to alcohol cues among adolescents and young adults in the laboratory and in daily life.2
Latent factor structure of behavioral economic heroin and cocaine demand curves.2
What influences demand for cigars among African American adult cigar smokers? Results from a hypothetical purchase task.2
Intersection of minority health, health disparities, and social determinants of health with psychopharmacology and substance use.2
Ibudilast moderates the effect of mood on alcohol craving during stress exposure.2
Anhedonia in tobacco withdrawal among African-American smokers.2
Real-world clinical characterization of subjects with depression treated with antidepressant drugs focused on (non-)genetic factors, pharmacokinetics, and clinical outcomes: GnG-PK/PD-AD study.2
Measuring subjective alcohol effects in daily life using contemporary young adult language.2
Cognitive-emotional mechanisms of alcohol intoxication-involved HIV-risk behavior among men who have sex with men (MSM).2
Attentional and approach biases to alcohol cues among young adult drinkers: An ecological momentary assessment study.2
Biochemical validation of self-reported electronic nicotine delivery system and tobacco heaviness of use.2
Acute tolerance to alcohol-induced impairment in cognitive performance.2
Effect of brief nicotine corrective messaging on nicotine beliefs in persons who use opioids.1
From if-then to here and now: Using personalized counterfactuals from past negative experiences to reduce future alcohol consequences.1
Alcohol demand and supersized alcopop consumption among undergraduate college students.1
Clinically meaningful individual differences in opioid withdrawal expression.1
Narrative theory v: Narratives about penalties resulting from illegal tobacco purchases increase psychological distress.1
Efficacy of lisdexamfetamine dimesylate for promoting occupational success in adolescents and young adults with attention-deficit/hyperactivity disorder.1
Real-time momentary mood as a predictor of college students’ prescription drug misuse in daily life: Direct links and the moderating role of background mental health.1
Meditation trips: A thematic analysis of the combined naturalistic use of psychedelics with meditation practices.1
E-liquid purchase as a function of workplace restriction in the experimental tobacco marketplace.1
A preliminary investigation of salivary α-amylase as a novel biomarker of subjective response to alcohol: A brief report.1
Disentangling the within- and between-person aspects of implicit alcohol associations on hazardous drinking.1
Implications of epidemic-pandemic convergence for routine care adoption of contingency management: A case study.1
Combustible cigarette smokers versus e-cigarette dual users among Latinx individuals: Differences in alcohol and drug use severity.1
Conditioned anti-immobility by ketamine: A comparison to escitalopram and bupropion.1
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