OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Genetics is 111. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Toward advances in retinoblastoma genetics in Kenya	887
Epigenetic memory in 3D	667
Deciphering the evolutionary dynamics of extrachromosomal DNA in human cancer	660
Mapping dog behavior	548
Role of gene–gene loops in fine-tuning cross-regulation	456
Machine learning drives genetic discovery for binge eating disorder	414
Identifying individuals at extreme risk of venous thromboembolism using polygenic risk scores	410
DNA polymerase ε produces elevated C-to-T mutations at methylated CpG dinucleotides	388
GeneMAP enables discovery of metabolic gene function	376
Predicting obesity from childhood	374
Cracking the histone code for prostate cancer therapy	348
Problems with dystopian representations in genetic futurism	334
Criteria for prioritizing trait-relevant genes	319
Defining the transcriptional landscape in the classical subtype of pancreatic cancer	318
Complete genomes of six ape species	286
The Solve-RD Solvathons as a pan-European interdisciplinary collaboration to diagnose patients with rare disease	280
An atlas of genetic determinants of forearm fracture	272
Author Correction: Single-cell atlas of the transcriptome and chromatin accessibility in the human retina	268
Chromatin loop proteomics finds a non-catalytic function for a histone demethylase	254
JMJD2 regulates enhancer–promoter interactions via biomolecular condensate formation	253
Temperature-induced RNA recoding in octopus	252
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas	250
Insights from three decades of BRCA1/2 modeling in mice	232
Genome-wide fine-mapping improves identification of causal variants	231
Tumor DNA methylation subtypes predict immunotherapy outcomes in pleural mesothelioma patients in the NIBIT-EPI-MESO study	230

Telomere-to-telomere sheep genome assembly identifies variants associated with wool fineness	228
Somatic mutations link focal onset to widespread neurodegeneration in ALS and FTD	228
Crosstalk between RNA m6A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells	220
Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease	216
Reactivation of embryonic genetic programs in tissue regeneration and disease	214
A chromatin-regulated biphasic circuit coordinates IL-1β-mediated inflammation	213
Understanding liver repair through space and time	211
Genome-wide RNA polymerase stalling shapes the transcriptome during aging	209
Dominant variants in major spliceosome U4 and U5 small nuclear RNA genes cause neurodevelopmental disorders through splicing disruption	209
Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways	208
In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization	208
Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize	207
The BAF chromatin remodeler synergizes with RNA polymerase II and transcription factors to evict nucleosomes	207
Mitochondrial DNA mosaicism in normal human somatic cells	189
Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development	187
Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases	184
Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes	182
Rare coding variant analysis for human diseases across biobanks and ancestries	181
Shared genetics of substance use disorders	180
Cicer super-pangenome provides insights into species evolution and agronomic trait loci for crop improvement in chickpea	180
A biology-aware mutation rate model for human germline	180
Genetic and non-genetic HLA disruption is widespread in lung and breast tumors	179
Genes influence complex traits through environments that vary between geographic regions	179
Identification of two intrinsic epithelial subtypes of colorectal cancer	178
Histone gene editing probes functions of H3K27 modifications in mammals	178
Finding cancer mutagens using signature analysis	178
Somatic mutations in the stomach	173
High-content genetic screens identify RNA-based mechanisms to target immune evasion	172
Synthetic surrogates improve power for genome-wide association studies of partially missing phenotypes in population biobanks	168
Single-cell expression QTL analyses of the human cerebellum reveal vulnerability of oligodendrocytes in essential tremor	168
APOBEC mutagenesis is a common process in normal human small intestine	168
Publisher Correction: A genetic module boosts grain yield and nitrogen use efficiency by improving nitrate transport in maize	168
Histone acetylation-dependent clustering of BRD2 instructs transcription dynamics	168
Genetic associations with educational fields	167
Safeguard repressor locks hepatocyte identity and blocks liver cancer	164
Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon	164
Proteome-wide model for human disease genetics	163
Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction	160
Interpreting cis-regulatory interactions from large-scale deep neural networks	160
RNA polymerase II dynamics shape enhancer–promoter interactions	159
Recycling enhancers	158
Finding causal genes underlying risk for coronary artery disease	157
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription	155
An alternative model for maternal mtDNA inheritance	153
Epigenetically driven and early immune evasion in colorectal cancer evolution	152
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas	151
Designing synthetic regulatory elements using the generative AI framework DNA-Diffusion	151
Establishing African genomics and bioinformatics programs through annual regional workshops	150
The emergence of metastasis in colorectal cancer	148
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity	145

Systematic prioritization of functional variants and effector genes underlying colorectal cancer risk	144
Human subcutaneous and visceral adipocyte atlases uncover classical and nonclassical adipocytes and depot-specific patterns	144
Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma	143
Increasing diversity in genomics requires investment in equitable partnerships and capacity building	143
Publisher Correction: APOBEC3 mutagenesis drives therapy resistance in breast cancer	142
Author Correction: Pangenome graphs and their applications in biodiversity genomics	141
Author Correction: The NAT1–bHLH110–CER1/CER1L module regulates heat stress tolerance in rice	139
Exploring the mammalian metabolome with DeepMet	138
Stromal immune cell signatures predict risk of progression in meningioma	136
Bayesian estimation of gene constraint from an evolutionary model with gene features	135
APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer	134
A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen	133
Natural variation in SBRR1 shows high potential for sheath blight resistance breeding in rice	132
When RNA methylation meets DNA methylation	132
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits	129
Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases	126
Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment	124
Solanum americanum genome-assisted discovery of immune receptors that detect potato late blight pathogen effectors	123
Suppressing a phosphohydrolase of cytokinin nucleotide enhances grain yield in rice	123
Redefining teleost phylogeny	122
Equity, ethics and the promise of partnership in genomic medicine	122
The Federated European Genome–Phenome Archive as a global network for sharing human genomics data	122
Sarcoma predisposition	121
SBRR1-R variant regulates sheath blight resistance in rice	121
Somatic recombination of repetitive elements	121
Sox2 expression can be regulated across boundaries generated by CTCF–cohesin loops	120
Genetic and biological insights into spontaneous coronary artery dissection	120
Improving estimates of loss-of-function constraint for short genes	119
Planting the milestones of human genetics in Senegal	118
Federated analysis of autosomal recessive coding variants in 29,745 developmental disorder patients from diverse populations	117
Epigenetic scars of Brca1 loss point toward breast cancer cell of origin	116
Polygenic basis for seedless grapes	116
Chromatin remembers ancestral DNA damage	113
Defining genome access of transcription factors	113
Regulators of androgen receptor activity revealed by CRISPR interference screens	112
A CT-dimer repeat expansion underlies a rare subtype of frontotemporal lobar degeneration	111
Mathematical modeling of neuroblastoma associates evolutionary patterns with outcomes	111