Journal of Drug Targeting

Papers
(The median citation count of Journal of Drug Targeting is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma67
Nose-to-brain delivery of transferrin-modified carmustine-loaded iron nanoparticles for enhanced glioblastoma treatment54
Significant metabolic alterations in patients with hepatitis B virus replication observed via serum untargeted metabolomics shed new light on hepatitis B virus infection43
Polymyxin B delivery systems: smart solutions for improved antibacterial activity and reduced toxicity40
Cancer cell membrane camouflaging mesoporous nanoplatform interfering with cellular redox homeostasis to amplify photodynamic therapy on oral carcinoma39
Resveratrol in ulcerative colitis: therapeutic mechanisms, animal model evidence and novel approaches38
Advancement in transporter-oriented nanoplatforms for cancer therapy32
Advances in targeted therapy for triple-negative breast cancer: a review of key antigens and recent advances31
Combined photodynamic therapy and hollow microneedle approach for effective non-invasive delivery of hypericin for the management of imiquimod-induced psoriasis31
Targeting Nrf2 signaling pathway: new therapeutic strategy for cardiovascular diseases29
Advances in nanomedicine for retinal drug delivery: overcoming barriers and enhancing therapeutic outcomes28
Correction27
Chitosan–β-glycerophosphate thermogelling microneedles for transdermal contraceptive delivery of levonorgestrel27
Emerging role of ferroptosis in diabetic retinopathy: a review26
Trends in iron oxide nanoparticles: a nano-platform for theranostic application in breast cancer26
Role of curcumin and its nanoformulations in the treatment of neurological diseases through the effects on stem cells25
Improved antidiabetic potential of quercetin-loaded chitosan–lecithin nanoparticles for effective glycaemic control24
Exosomes derived from cancer cells relieve inflammatory bowel disease in mice22
Correction22
Engineered extracellular vesicle with RAGE-antagonist peptide for delivery of anti-miRNA155 oligonucleotides to inflammatory lung cells21
Interactions and communications in lung tumour microenvironment: chemo/radiotherapy resistance mechanisms and therapeutic targets21
Ferroptosis-targeting drugs in breast cancer21
Sequential targeting dual-responsive magnetic nanoparticle for improved therapy of lung metastatic breast cancer21
Micro and nanorobot-based drug delivery: an overview21
Absorption enhancer approach for protein delivery by various routes of administration: a rapid review21
Stimulus-responsive peptide hydrogels: a safe and least invasive administration approach for tumor treatment20
Recent progress in biomimetic nanomedicines based on versatile targeting strategy for atherosclerosis therapy19
Erythrocyte-derived liposomes for the treatment of inflammatory diseases19
Targeting lipopolysaccharides in gram-negative sepsis: therapeutic advances and challenges19
Redox responsive functionalised mesoporous silica nanoparticle for targeted drug delivery of doxorubicin19
Dehydrocurvularin-loaded mPEG-PLGA nanoparticles for targeted breast cancer drug delivery: preparation, characterization, in vitro , and in vivo 18
Identifying factors controlling cellular uptake of gold nanoparticles by machine learning18
Redefining hepatocellular carcinoma treatment: nanotechnology meets tumor immune microenvironment18
Comprehensive insights into herbal P-glycoprotein inhibitors and nanoformulations for improving anti-retroviral therapy efficacy17
siRNA targeting PARP-1 alleviates diabetic peripheral neuropathy in a streptozotocin-induced rat model17
Emerging trends in viral infection inhibition using a chitosan-based drug delivery system17
Crafting two-dimensional materials for contrast agents, drug, and heat delivery applications through green technologies16
In vivo application of magnetic molecularly imprinted polymer in rheumatoid arthritis rat model16
pH-responsive self-assembled nanoparticles for tumor-targeted drug delivery16
Formulation, optimisation, and evaluation of Lornoxicam-loaded Novasomes for targeted ulcerative colitis therapy: in vitro and in vivo investigations16
Isoform-specific vs. isoform-universal drug targeting: a new targeting paradigm illustrated by new anti-ICAM-1 antibodies16
Harnessing the synergistic potential of NK1R antagonists and selective COX-2 inhibitors for simultaneous targeting of TNBC cells and cancer stem cells16
The role of green synthesis metal and metal oxide nanoparticles in oral cancer therapy: a review15
Targeted delivery of epirubicin to cancerous cell using copper sulphide nanoparticle coated with polyarginine and 5TR1 aptamer15
Combination therapy based on targeted nano drug co-delivery systems for liver fibrosis treatment: a review15
Lipo/TK-CDN/TPP/Y6 nanoparticles inhibit cutaneous melanoma formation15
From adhesion to invasion: the multifaceted roles of Mycobacterium tuberculosis lipoproteins15
microRNAs: critical targets for treating rheumatoid arthritis angiogenesis14
Emerging biologics for the treatment of pulmonary arterial hypertension14
Non-coding RNAs enhance the apoptosis efficacy of therapeutic agents used for the treatment of glioblastoma multiform14
An overview of phospholipid enriched-edge activator-based vesicle nanocarriers: new paradigms to treat skin cancer14
L-Carnosine loaded chondroitin sulphate functionalized proposomes as an effective tool for transdermal rheumatoid arthritis management14
Angiopep-2 modified dual drug-loaded liposomes with brain targeting functionality mitigate Alzheimer’s disease-related symptoms in APP/PS-1 mice13
Advances, challenge and prospects in cell-mediated nanodrug delivery for cancer therapy: a review13
Multi-strategic approaches for enhancing active transportation using self-emulsifying drug delivery system13
Folate receptor-mediated targeted therapy for rheumatoid arthritis by methotrexate-phospholipid complex nano-emulsions13
Research progress of p38 as a new therapeutic target against morphine tolerance and the current status of therapy of morphine tolerance13
Recent advances in curcumin-based nanoformulations in diabetes12
The Golgi apparatus as a strategic target in cancer: mechanisms, diagnosis and therapeutic opportunities12
Pulmonary delivery of a recombinant RAGE antagonist peptide derived from high-mobility group box-1 in a bleomycin-induced pulmonary fibrosis animal model12
Methotrexate-Loaded solid lipid nanoparticles enhance the viability of cutaneous flaps: potential for surgical wound healing12
Exploring the translocation behaviours in vivo of herpetrione amorphous nanoparticles via oral delivery12
Drug repurposing strategies and key challenges for COVID-19 management12
Mesencephalic astrocyte-derived neurotrophic factor restores blood–brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway12
Recent developments in nanoparticles for the treatment of diabetes12
Smart design and preclinical evaluation of folate-functionalized mesoporous nanoparticles for targeted paclitaxel delivery in cancer therapy12
Study on lipid nanomicelles targeting placenta for the treatment of preeclampsia12
A novel micellar carrier to reverse multidrug resistance of tumours: TPGS derivatives with end-grafted cholesterol12
Smart delivery of epirubicin to cancer cells using aptamer-modified ferritin nanoparticles12
MicroRNA-206 inhibition and activation of the AMPK/Nampt signalling pathway enhance sevoflurane post-conditioning-induced amelioration of myocardial ischaemia/reperfusion injury12
Valeric acid reduction by chitosan oligosaccharide induces autophagy in a Parkinson’s disease mouse model12
Targeted therapy of tumour microenvironment by gold nanoparticles as a new therapeutic approach11
ROS1-positive non-small cell lung cancer (NSCLC): biology, diagnostics, therapeutics and resistance11
Lymphatic targeting for therapeutic application using nanoparticulate systems11
Green synthesis of magnesium oxide nanoparticles using the extract of Falcaria vulgaris to enhance the healing of burn wounds11
Boosting breast cancer immunotherapy through targeted siRNA delivery and sequential chemotherapy11
Edoxaban enfolded beta-1,4-poly- d -glucosamine nanoparticles for targeting eponym Stuart–Prower factor for treatment of venous thrombosis11
ceRNA networks in gynecological cancers progression and resistance11
In vitro studies support clinical trials showing platelet-rich fibrin-mediated local delivery of antibiotics improves outcomes in impacted mandibular third molar surgery11
Development of mRNA nano-vaccines for COVID-19 prevention and its biochemical interactions with various disease conditions and age groups10
Nanotransethosomal dual-drug loaded gel of methotrexate and mangiferin as a potent synergistic intervention for rheumatoid arthritis via transdermal delivery10
Calpeptin promotes osteogenesis through the Dlx3–RUNX2 pathway: in vitro and in vivo evidence for a dual-action osteoporosis therapy10
The combined treatment of gold nanoparticles associated with photobiomodulation accelerate the healing of dermonecrotic lesion10
Efficient drug delivery by novel cell-penetrating peptide derived from Midkine, with two heparin binding sites braced by a length-specific helix10
Role of liposomes in chemoimmunotherapy of breast cancer9
Mannosylated chitosan-decorated PLGA nanoparticles for targeted pulmonary delivery of isoniazid: a promising approach in the treatment of tuberculosis9
Advancements in colorectal cancer immunotherapy: from CAR-T cells to exosome-based therapies9
A paradigm use of monoclonal antibodies-conjugated nanoparticles in breast cancer treatment: current status and potential approaches9
Nanoparticle-Based gene therapy strategies in retinal delivery9
Olaparib@human serum albumin nanoparticles as sustained drug-releasing tumour-targeting nanomedicine to inhibit growth and metastasis in the mouse model of triple-negative breast cancer8
Empagliflozin alleviates myocardial I/R injury and cardiomyocyte apoptosis via inhibiting ER stress-induced autophagy and the PERK/ATF4/Beclin1 pathway8
Advancement on nanoparticles-based approaches for the management of rheumatoid arthritis (RA): molecular mechanism, toxicity, and clinical perspectives8
Anti-GPC3 antibody and cell-penetrating peptide CPP44 dual-ligand modified liposomes for targeted delivery of arsenic trioxide in the treatment of hepatocellular carcinoma8
Development of linagliptin-loaded liposomes using aspartic acid conjugate for bone-targeted delivery to combat osteoporosis8
Overview of role of survivin in cancer: expression, regulation, functions, and its potential as a therapeutic target8
Macrophage membrane biomimetic drug delivery system: for inflammation targeted therapy8
Light mediated drug delivery systems: a review8
Recent advancements in nanomedicine based lipid metabolism for tumour immunotherapy8
Methodological advances in liposomal encapsulation efficiency determination: systematic review and analysis7
Enhanced pharmacokinetic approach for anastrozole via macromolecule-based silk fibroin nanoparticles incorporated in situ injectables for oestrogen-positive breast cance7
Legumain protease-sheddable PEGylated, tuftsin-modified nanoparticles for selective targeting to tumour-associated macrophages7
Albumin-encapsulated HSP90-PROTAC BP3 nanoparticles not only retain protein degradation ability but also enhance the antitumour activity of BP3 in vivo7
Octreotide and Octreotide-derived delivery systems7
A platelet-cloaking tetramethylprazine-loaded microemulsion for improved therapy of myocardial ischaemia/reperfusion injury7
Fisetin topical delivery via ascorbyl palmitate/hyaluronan-enhanced limosomes: a novel paradigm for preventing UVB-induced skin photoaging7
2,2,6,6-tetramethylpiperidin-1-oxyl: a new potential targeted ligand based on lipid peroxidation for targeted drug delivery7
Chemical modification of curcumin increases its potency against hypopharyngeal carcinoma7
Patient-derived organoid models of malignant phyllodes tumours for drug sensitivity testing and identification of targeted therapeutic strategies7
DOX-loaded mesoporous hydroxyapatite modified by hyaluronic acid can achieve efficient targeted therapy for lung cancer7
Cationic liposome decorated with cyclic RGD peptide for targeted delivery of anti-STAT3 siRNA to melanoma cancer cells7
Integrating machine learning and multitargeted drug design to combat antimicrobial resistance: a systematic review7
Aptamers: ushering in new hopes in targeted glioblastoma therapy7
Exploring the potential of ferulic acid-loaded nanostructured lipid carriers: angiotensin inhibition via docking, formulation and pharmacokinetic and pharmacodynamics studies7
Ofirnoflast: a first-in-class NEK7-targeted inhibitor of the NLRP3 inflammasome7
Niosomal formulation for antibacterial applications7
Preparation of cationic liposomes loaded with Sirtuin 6 plasmid for the treatment of arthritis in rats6
Protein biomarker modulation and wound healing efficacy of mentha piperita-based green-synthesized silver nanoparticles in alloxan-induced diabetic rats6
Comparison of a poloxamer-based thermally sensitive gel and an HPMC-based standard gel used to increase sildenafil citrate retention in the uterus6
The role of PTP1B in cardiometabolic disorders and endothelial dysfunction6
Titanium surface polyethylene glycol hydrogel and gentamicin-loaded cross-linked starch microspheres release system for anti-infective drugs6
Development and optimization of curcumin-loaded solid lipid nanoparticles using Box-Behnken design and evaluation of its efficacy in modulating morphine-induced conditioned place preference: 6
Formulation and optimisation of nanoemulsions for enhancing topical delivery of methotrexate in CFA induced arthritis rat model6
Efficacy of intranasal delivery of VEGFR inhibitors to cervical lymph nodes for inhibiting tongue cancer metastasis in mice6
Research progress of microneedle drug delivery system in the treatment of autoimmune diseases6
Nanotechnology-driven approaches for the early detection and targeted treatment of Alzheimer’s disease6
Molecular mechanism of Wilms tumour 1-associated protein in diabetes-related dry eye disease by mediating m6A methylation modification of lncRNA NEAT16
Poly-γ-glutamic acid coating polymeric nanoparticles enhance renal drug distribution and cellular uptake for diabetic nephropathy therapy6
Correction6
Perspectives of metformin use in endometrial cancer and other gynaecological malignancies6
Celastrol nano-emulsions selectively regulate apoptosis of synovial macrophage for alleviating rheumatoid arthritis6
Molecular and cellular biology of PCSK9: impact on glucose homeostasis6
Bone morphogenetic protein (BMP)9 in cancer development: mechanistic, diagnostic, and therapeutic approaches?6
Identification and validation of Sertoli cell homing peptides as molecular steering for testis targeted drug delivery6
Nano-composite hydrogels of Cu-Apa micelles for anti-vasculogenic mimicry6
Advancements in curcumin-loaded PLGA nanoparticle delivery systems: progressive strategies in cancer therapy6
A review of recombinant HER3 affibodies with an effective diagnostic view of cancer cells6
Human plasma-derived exosomal gel: a biomimetic cargo for the transdermal delivery of methotrexate6
Intravaginal co-delivery of myoinositol and metformin via dual MPPs-loaded gel for PCOS amelioration: an in-vivo study in a rat model5
Strategies of overcoming osimertinib resistance in EGFR-mutated non-small cell lung cancer5
The potential use of bacteria and their derivatives as delivery systems for nanoparticles in the treatment of cancer5
Spanlastics: a novel elastic drug delivery system with potential applications via multifarious routes of administration5
Progress in research and development of temozolomide brain-targeted preparations: a review5
Recent advances in cancer cell bionic nanoparticles for tumour therapy5
Liver-targeted delivery based on prodrug: passive and active approaches5
Regulation of IFP in solid tumours through acoustic pressure to enhance infiltration of nanoparticles of various sizes5
Cell-based immunotherapy in oesophageal cancer5
Evaluation of mRNA lipoplexes prepared using modified ethanol injection method as a tumour vaccine5
A novel mucoadhesive phytic acid grafted chitosan nanocarrier encapsulated with cisplatin for site-specific cervical cancer therapy: in vitro and 5
Design and in vivo evaluation of a multi-epitope vaccine that suppresses tumour growth in a murine colorectal cancer model5
Harnessing machine learning potential for personalised drug design and overcoming drug resistance5
Retraction statement5
Recent advances in PAMAM mediated nano-vehicles for targeted drug delivery in cancer therapy5
Recent advances in hepatocellular carcinoma therapeutic strategies and imaging-guided treatment5
Evaluation of anti-diabetic effects of glimepiride/metformin cocrystal5
Off-target effects of the NADPH oxidase inhibitor mitoapocynin-encapsulated nanoparticles and free-drug oral treatment in a rat DFP model of neurotoxicity5
Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer5
Review on anti-tumour lipid nano drug delivery systems of traditional Chinese medicine5
Epidermal growth factor receptors unveiled: a comprehensive survey on mutations, clinical insights of global inhibitors, and emergence of heterocyclic derivatives as EGFR inhibitors5
Igniting tumour microenvironment in triple-negative breast cancer using a mannose/hyaluronic acid dual-coated Ganoderma polysaccharide-superparamagnetic iron oxide nanocomplex for combinational therap5
Selection of LRP1 ligand phage-displayed single domain antibody that transmigrates BBB5
State-of-the-art drug delivery system to target the lymphatics5
Roflumilast-loaded nanostructured lipid carriers attenuate oxidative stress and neuroinflammation in Parkinson’s disease model4
TGFβ1/integrin β3 positive feedback loop contributes to acquired EGFR TKI resistance in EGFR-mutant lung cancer4
Colon-targeted delivery of niclosamide from solid dispersion employing a pH-dependent polymer via hotmelt extrusion for the treatment of ulcerative colitis in mice4
Advanced polymers and recent advancements on gastroretentive drug delivery system; a comprehensive review4
Insulin for oral bone tissue engineering: a review on innovations in targeted insulin-loaded nanocarrier scaffold4
S-(N,N-diethyldithiocarbamoyl)-N-acetyl- l -cysteine for the treatment of non-small cell lung cancer through regulating NF-κB signalling pathway without neurotoxicit4
Herbal nanoparticles: a targeted approach for neurodegenerative disorder treatment4
A pH-Driven indomethacin-loaded nanomedicine for effective rheumatoid arthritis therapy by combining with photothermal therapy4
Delivery vehicles for light-mediated drug delivery: microspheres, microbots, and nanoparticles: a review4
Novel studies on Drosophila melanogaster model reveal the roles of JNK-Jak/STAT axis and intestinal microbiota in insulin resistance4
Unlocking hope: GSK-3 inhibitors and Wnt pathway activation in Alzheimer’s therapy4
Therapeutic liposomes synergize with active molecules to enhance targeted therapy4
An all-in-one nanoparticle for overcoming drug resistance: doxorubicin and elacridar co-loaded folate receptor targeted PLGA/MSN hybrid nanoparticles4
Antibody-drug conjugates targeting DDR1 as a novel strategy for treatment of breast cancer4
A review on endoplasmic reticulum-dependent anti-breast cancer activity of herbal drugs: possible challenges and opportunities4
Nanoparticles toxicity: an overview of its mechanism and plausible mitigation strategies4
Effect of a novel siRNA delivery system, siRNA ternary complex, on melanoma lung metastasis4
Smart nanocarriers for enzyme-activated prodrug therapy4
Signalling in pancreatic cancer: from pathways to therapy4
Plant-based natural products in cancer therapeutics4
Recent advancement on albumin nanoparticles in treating lung carcinoma4
Emerging advances in nano-biomaterial assisted amyloid beta chimeric antigen receptor macrophages (CAR-M) therapy: reducing plaque burden in Alzheimer’s disease4
The combination of linagliptin and metformin rescues bone loss in type 2 diabetic osteoporosis4
Correction4
Efficacy and safety of valsartan–novasomes in the mitigation of atherosclerosis-associated diabetes mellitus: in vitro and in vivo assessm4
Synergistically engineered nanotransethosomes for co-delivery of methotrexate and baicalin for enhanced transdermal delivery against rheumatoid arthritis: formulation, characterisation and in vivo pha4
An extensive review on lung cancer therapeutics using machine learning techniques: state-of-the-art and perspectives4
Preparation, in vitro and in vivo evaluation of phloretin-loaded TPGS/Pluronic F68 modified mixed micelles with enhanced bioavailability a4
Breast cancer cell targeting of L-leucine-PLGA conjugated hybrid solid lipid nanoparticles of betulin via L-amino acid transport system-14
Research progress of treating ulcerative colitis and colon cancer by using oral colon targeted drug delivery system based on polymer micelles3
Surface-functionalised polymeric nanoparticles for breast cancer treatment: processes and advances3
Recent advancements in nanoparticle-based topical drug delivery systems for psoriasis treatment3
Cetuximab-conjugated PLGA nanoparticles as a prospective targeting therapeutics for non-small cell lung cancer3
Role of exosomes in tumour growth, chemoresistance and immunity: state-of-the-art3
The enhanced surface permeability and retention effect of topically administrated nanoparticles3
Artificial intelligence-based molecular property prediction of photosensitising effects of drugs3
SUPRADES: unlocking the versatility of cyclodextrin-based deep eutectic solvents3
Ferroptosis in renal fibrosis: a mini-review3
Validation of ZIP4 as a tumour-associated antigen for nanotargeting3
Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide3
Engineered anti-EGFRvIII targeted exosomes induce apoptosis in glioblastoma multiforme3
Relationship between ferroptosis and mitophagy in renal fibrosis: a systematic review3
Carbon Nanodots in Breast Cancer Management: Emerging Tools for Diagnosis and Therapy3
Delivery of MERS antigen encapsulated in α-GalCer-bearing liposomes elicits stronger antigen-specific immune responses3
Factors of faecal microbiota transplantation applied to cancer management3
Nano-based drug delivery systems in hepatocellular carcinoma3
Enhanced antitumor activity induced by a DNA vaccine encoding E7 antigen fused to an ERAD-targeting sequence3
Nanoreactor activated in situ for starvation-chemodynamic therapy of breast cancer3
Brain targeted polymeric micelles as drug carriers for ischaemic stroke treatment3
Nano-medicine therapy reprogramming metabolic network of tumour microenvironment: new opportunity for cancer therapies3
Understanding the role of ethosomes in rheumatoid arthritis: innovative solutions to challenges in transdermal delivery of synthetic drugs and phytoconstituents3
Formulation development of tocopherol polyethylene glycol nanoengineered polyamidoamine dendrimer for neuroprotection and treatment of Alzheimer disease3
Demonstration of ultrasound-mediated therapeutic delivery of fibrin-targeted pioglitazone-loaded echogenic liposomes into the arterial bed for attenuation of peri-stent restenosis3
The applications of targeted delivery for gene therapies in hearing loss3
Epigenetic modulation: Research progress on histone acetylation levels in major depressive disorders3
Effects and mechanisms of natural plant active compounds for the treatment of osteoclast-mediated bone destructive diseases3
Harnessing exosome-based drug delivery for the management of pregnancy-related disorders: a new frontier in obstetric therapeutics3
Multifunctional metal complex-based gene delivery for tumour immune checkpoint blockade combination therapy3
Her-2-directed systemic delivery of fatty acid synthase (FASN) siRNA with novel liposomal carrier systems in the breast cancer mouse model3
Therapeutic implication of targeting mitochondrial drugs designed for efferocytosis dysfunction3
Nanotransethosomal co-drug delivery system of diclofenac sodium and rosmarinic acid against rheumatoid arthritis: design, formulation, characterisation and pre-clinical studies3
0.10895490646362