Journal of Drug Targeting

Article	Citations
A comprehensive review on the antiviral activities of chalcones	62
CRISPR-cas systems based molecular diagnostic tool for infectious diseases and emerging 2019 novel coronavirus (COVID-19) pneumonia	56
Mesoporous silica nanoparticles: synthesis methods and their therapeutic use-recent advances	51
Carbon-based nanomaterials for targeted cancer nanotherapy: recent trends and future prospects	50
A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: challenges analysis and recent advances	34
New advances in brain-targeting nano-drug delivery systems for Alzheimer's disease	32
Pharmacological and non-pharmacological efforts at prevention, mitigation, and treatment for COVID-19	31
Improved oral delivery of quercetin with hyaluronic acid containing niosomes as a promising formulation	31
Stability issues and approaches to stabilised nanoparticles based drug delivery system	29
Polo-like Kinase 1 as an emerging drug target: structure, function and therapeutic implications	28
Non-surgical osteoarthritis therapy, intra-articular drug delivery towards clinical applications	28
The relevant targets of anti-oxidative stress: a review	28
3D printing technology in healthcare: applications, regulatory understanding, IP repository and clinical trial status	28
Manganese dioxide (MnO2) based nanomaterials for cancer therapies and theranostics	27
Targetting ferroptosis for blood cell-related diseases	27
ABC transporters in breast cancer: their roles in multidrug resistance and beyond	26
Pharmacotherapy in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety	26
Fabrication and characterisation of self-applicating heparin sodium microneedle patches	26
Current status of micro/nanomotors in drug delivery	25
Potential inhibitors of SARS-CoV-2: recent advances	24
Bioengineered smart bacterial carriers for combinational targeted therapy of solid tumours	24
Improving anti-tumour efficacy of PEGylated liposomal doxorubicin by dual targeting of tumour cells and tumour endothelial cells using anti-p32 CGKRK peptide	24
Active-site molecular docking of nigellidine with nucleocapsid–NSP2–MPro of COVID-19 and to human IL1R–IL6R and strong antioxidant role of Nigella sativa in experimental rats	23
Mitochondria autophagy: a potential target for cancer therapy	22
Dual functional nanoparticles efficiently across the blood–brain barrier to combat glioblastoma via simultaneously inhibit the PI3K pathway and NKG2A axis	22

Niosomal formulation for antibacterial applications	21
Nano drug delivery system reconstruct tumour vasculature for the tumour vascular normalisation	21
An updated review on exosomes: biosynthesis to clinical applications	20
Development, optimisation and evaluation of chitosan nanoparticles of alendronate against Alzheimer’s disease in intracerebroventricular streptozotocin model for brain delivery	20
Cationic liposome decorated with cyclic RGD peptide for targeted delivery of anti-STAT3 siRNA to melanoma cancer cells	19
Empagliflozin alleviates myocardial I/R injury and cardiomyocyte apoptosis via inhibiting ER stress-induced autophagy and the PERK/ATF4/Beclin1 pathway	19
A γ-cyclodextrin-based metal–organic framework (γ-CD-MOF): a review of recent advances for drug delivery application	19
New insights into the role of co-receptor neuropilins in tumour angiogenesis and lymphangiogenesis and targeted therapy strategies	19
Mitochondrial delivery of microRNA mimic let-7b to NSCLC cells by PAMAM-based nanoparticles	18
Depleting microRNA-146a-3p attenuates lipopolysaccharide-induced acute lung injury via up-regulating SIRT1 and mediating NF-κB pathway	18
Core-shell nanotherapeutics with leukocyte membrane camouflage for biomedical applications	18
MicroRNA-185 activates PI3K/AKT signalling pathway to alleviate dopaminergic neuron damage via targeting IGF1 in Parkinson’s disease	17
Nanomedicine and chemotherapeutics drug delivery: challenges and opportunities	16
Nanoliposomes as drug delivery systems: safety concerns	16
Genetically engineered exosomes display RVG peptide and selectively enrich a neprilysin variant: a potential formulation for the treatment of Alzheimer’s disease	16
Methods for fabricating oxygen releasing biomaterials	16
Advancements of compounds targeting Wnt and Notch signalling pathways in the treatment of inflammatory bowel disease and colon cancer	15
Immunotoxins and nanobody-based immunotoxins: review and update	15
PEGylated DOX-coated nano graphene oxide as pH-responsive multifunctional nanocarrier for targeted drug delivery	15
Micro and nanorobot-based drug delivery: an overview	15
The role of peptide-based therapeutics in oncotherapy	15
Progress in tumour-targeted drug delivery based on cell-penetrating peptides	15
A novel progress of drug delivery system for organelle targeting in tumour cells	15
The mechanisms of lncRNA GAS5 in cardiovascular cells and its potential as novel therapeutic target	15
Targeting PRAS40: a novel therapeutic strategy for human diseases	15
Exosome-mediated transfer of circHIPK3 promotes trastuzumab chemoresistance in breast cancer	15
Mesencephalic astrocyte-derived neurotrophic factor restores blood–brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway	15
EGFR and anti-EGFR nanobodies: review and update	15
Erlotinib entrapped in cholesterol-depleting cyclodextrin nanoparticles shows improved antitumoral efficacy in 3D spheroid tumors of the lung and the liver	14
Influences of different sugar ligands on targeted delivery of liposomes	14
Inhibition of microRNA-10b-5p up-regulates HOXD10 to attenuate Alzheimer’s disease in rats via the Rho/ROCK signalling pathway	14
Iron metabolism in Pseudomonas aeruginosa biofilm and the involved iron-targeted anti-biofilm strategies	14
Biomedical application of chondroitin sulfate with nanoparticles in drug delivery systems: systematic review	14
Efficient antiglioblastoma therapy in mice through doxorubicin-loaded nanomicelles modified using a novel brain-targeted RVG-15 peptide	13
MicroRNA-135b-5p promotes endothelial cell proliferation and angiogenesis in diabetic retinopathy mice by inhibiting Von Hipp-el-Lindau and elevating hypoxia inducible factor α expression	13
Innovative topical niosomal gel formulation containing diclofenac sodium (niofenac)	13
New generation of viral nanoparticles for targeted drug delivery in cancer therapy	13
Effect of polymer microneedle pre-treatment on drug distributions in the skin in vivo	13
Delivery of RGD-modified liposome as a targeted colorectal carcinoma therapy and its autophagy mechanism	13
A mechanistic perspective on targeting bacterial drug resistance with nanoparticles	13
TIGIT/PVR and LncRNA ANRIL dual-targetable PAMAM polymeric nanoparticles efficiently inhibited the hepatoma carcinoma by combination of immunotherapy and gene therapy	13
Formulation development of tocopherol polyethylene glycol nanoengineered polyamidoamine dendrimer for neuroprotection and treatment of Alzheimer disease	12
Non-ionic surfactant vesicles as a carrier system for dermal delivery of (+)-Catechin and their antioxidant effects	12
Significant metabolic alterations in patients with hepatitis B virus replication observed via serum untargeted metabolomics shed new light on hepatitis B virus infection	12
Effects and mechanisms of natural plant active compounds for the treatment of osteoclast-mediated bone destructive diseases	12
Mycobacterial ethambutol responsive genes and implications in antibiotics resistance	12
Bevacizumab combined with apatinib enhances antitumor and anti-angiogenesis effects in a lung cancer model in vitro and in vivo	12
Role of exosomes in tumour growth, chemoresistance and immunity: state-of-the-art	12
Functionality of receptor targeted zinc-insulin quantum clusters in skin tissue augmentation and bioimaging	12
Exosome vesicle as a nano-therapeutic carrier for breast cancer	12

Envelope proteins as antiviral drug target	12
HSP60 in cancer: a promising biomarker for diagnosis and a potentially useful target for treatment	11
Enzyme-instructed self-assembly of the stereoisomers of pentapeptides to form biocompatible supramolecular hydrogels	11
Hyaluronic acid-coated metal-organic frameworks benefit the ROS-mediated apoptosis and amplified anticancer activity of artesunate	11
Mitochondrial dysfunction and mitochondrion-targeted therapeutics in liver diseases	11
Sirtuins as therapeutic targets for improving delayed wound healing in diabetes	11
Current status and applications of animal models in pre-clinical development of orally administered insulin-loaded nanoparticles	11
Opportunities and obstacles of targeted therapy and immunotherapy in small cell lung cancer	11
Lipo-PEG nano-ocular formulation successfully encapsulates hydrophilic fluconazole and traverses corneal and non-corneal path to reach posterior eye segment	10
Tumour microenvironment-responsive nanoplatform based on biodegradable liposome-coated hollow MnO2 for synergistically enhanced chemotherapy and photodynamic therapy	10
Role of lipid nanocarriers for enhancing oral absorption and bioavailability of insulin and GLP-1 receptor agonists	10
Peptides-based therapy and diagnosis. Strategies for non-invasive therapies in cancer	10
Silencing long non-coding RNA HNF1A-AS1 inhibits growth and resistance to TAM of breast cancer cells via the microRNA-363/SERTAD3 axis	10
Delivery of toll-like receptor agonists by complement C3-targeted liposomes activates immune cells and reduces tumour growth	10
Light mediated drug delivery systems: a review	10
Four generations of EGFR TKIs associated with different pathogenic mutations in non-small cell lung carcinoma	9
Application of nanoparticles in drug delivery for the treatment of osteosarcoma: focussing on the liposomes	9
Improving protection effects of eucalyptol via carboxymethyl chitosan-coated lipid nanoparticles on hyperglycaemia-induced vascular endothelial injury in rats	9
Biomimetic Ca2+ nanogenerator based on ions interference strategy for tumour-specific therapy	9
Lectin recognition and hepatocyte endocytosis of GalNAc-decorated nanostructured lipid carriers	9
Engineered anti-EGFRvIII targeted exosomes induce apoptosis in glioblastoma multiforme	9
Opportunity in nanomedicine to counter the challenges of current drug delivery approaches used for the treatment of malaria: a review	9
Coadministration of liposomal methylglyoxal increases the activity of amphotericin B againstCandida albicansin leukopoenic mice	9
ZIF-8 nanoparticles coated with macrophage-derived microvesicles for sustained, targeted delivery of dexamethasone to arthritic joints	9
Ultrasound image-guided gene delivery using three-dimensional diagnostic ultrasound and lipid-based microbubbles	9
PVAT targets VSMCs to regulate vascular remodelling: angel or demon	9
A pH-Driven indomethacin-loaded nanomedicine for effective rheumatoid arthritis therapy by combining with photothermal therapy	9
Effect of Malt-PEG-Abz@RSL3 micelles on HepG2 cells based on NADPH depletion and GPX4 inhibition in ferroptosis	9
Machine learning-guided evolution of BMP-2 knuckle Epitope-Derived osteogenic peptides to target BMP receptor II	9
Metformin combats obesity by targeting FTO in an m6A-YTHDF2-dependent manner	9
How to use macrophages to realise the treatment of tumour	8
Drug repurposing strategies and key challenges for COVID-19 management	8
Non-coding RNAs enhance the apoptosis efficacy of therapeutic agents used for the treatment of glioblastoma multiform	8
Application of nanotechnology in management and treatment of diabetic wounds	8
Engineering mesenchymal stem cells: a novel therapeutic approach in breast cancer	8
Cannabis as a potential compound against various malignancies, legal aspects, advancement by exploiting nanotechnology and clinical trials	8
Molecular and cellular biology of PCSK9: impact on glucose homeostasis	8
New designed pH-responsive histidine-rich peptides with antitumor activity	8
Legumain protease-sheddable PEGylated, tuftsin-modified nanoparticles for selective targeting to tumour-associated macrophages	8
Dual variable of drug loaded micelles in both particle and electrical charge on gastric cancer treatment	8
Development of stimuli-responsive intelligent polymer micelles for the delivery of doxorubicin	8
Combination therapy based on targeted nano drug co-delivery systems for liver fibrosis treatment: a review	8
Therapeutic advances in cardiac targeted drug delivery: from theory to practice	8
Dual functional liposomes carrying antioxidants against tau hyperphosphorylation and apoptosis of neurons	8
Diethyldithiocarbamate encapsulation reduces toxicity and promotes leishmanicidal effect through apoptosis-like mechanism in promastigote and ROS production by macrophage	7
Metformin protects cardiomyocytes against oxygen-glucose deprivation injury by promoting autophagic flux through AMPK pathway	7
Injectablein-situgel depot system for targeted delivery of biologics to the retina	7
Tumour targeted polymer nanoparticles co-loaded with docetaxel and siCCAT2 for combination therapy of lung cancer	7
Role of curcumin and its nanoformulations in the treatment of neurological diseases through the effects on stem cells	7
Lymphatic targeting for therapeutic application using nanoparticulate systems	7
The ameliorating approach of nanorobotics in the novel drug delivery systems: a mechanistic review	7
The role of miRNAs and lncRNAs in conferring resistance to doxorubicin	7
Olaparib@human serum albumin nanoparticles as sustained drug-releasing tumour-targeting nanomedicine to inhibit growth and metastasis in the mouse model of triple-negative breast cancer	7
ROS1-positive non-small cell lung cancer (NSCLC): biology, diagnostics, therapeutics and resistance	7
Discovery of necrosis avidity of rhein and its applications in necrosis imaging	6
Therapeutic drugs and drug delivery systems targeting stromal cells for cancer therapy: a review	6
Location of stimuli-responsive peptide sequences within silk-elastinlike protein-based polymers affects nanostructure assembly and drug–polymer interactions	6
Current approaches and future prospects of nanofibers: a special focus on antimicrobial drug delivery	6
Characteristics of SARS-CoV2 that may be useful for nanoparticle pulmonary drug delivery	6
Macrophage targeted triptolide micelles capable of cGAS-STING pathway inhibition for rheumatoid arthritis treatment	6
Nanosystem functionalization strategies for prostate cancer treatment: a review	6
Advances in autophagy as a target in the treatment of tumours	6
Fabrication techniques for the preparation of orally administered insulin nanoparticles	6
Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer	6
Vascular priming with RRx-001 to increase the uptake and accumulation of temozolomide and irinotecan in orthotopically implanted gliomas	6
miR-1/133a and miR-206/133b clusters overcome HGF induced gefitinib resistance in non-small cell lung cancers with EGFR sensitive mutations	6
Novel polysaccharide building hybrid nanoparticles: remodelling TAMs to target ERα-positive breast cancer	6
Smart delivery of epirubicin to cancer cells using aptamer-modified ferritin nanoparticles	6
Detecting and targeting neurodegenerative disorders using electrospun nanofibrous matrices: current status and applications	6
Virulence-attenuated Salmonella engineered to secrete immunomodulators reduce tumour growth and increase survival in an autochthonous mouse model of breast cancer	5
T807-modified human serum albumin biomimetic nanoparticles for targeted drug delivery across the blood–brain barrier	5
Exploiting drug delivery systems for oral route in the peptic ulcer disease treatment	5
Tumour targetable and microenvironment-responsive nanoparticles simultaneously disrupt the PD-1/PD-L1 pathway and MAPK/ERK/JNK pathway for efficient treatment of colorectal cancer	5
Neglected tropical diseases and infectious illnesses: potential targeted peptides employed as hits compounds in drug design	5
Salmonella entericaTyphimurium engineered for nontoxic systemic colonization of autochthonous tumors	5
Graphene quantum dots (GQDs) nanoarchitectonics for theranostic application in lung cancer	5
Novel anti-PD-L1 peptide selected from combinatorial phage library inhibits tumor cell growth and restores T-cell activity	5
Recent advancement on albumin nanoparticles in treating lung carcinoma	5
Dual-targeted colon-based integrated micelle drug delivery system for treatment of ulcerative colitis	5
Recent advances in hepatocellular carcinoma therapeutic strategies and imaging-guided treatment	5

Poly-γ-glutamic acid coating polymeric nanoparticles enhance renal drug distribution and cellular uptake for diabetic nephropathy therapy	5
Role of sirtuin-1 (SIRT1) in hypoxic injury in pancreatic β-cells	5
Biomimetic graphene oxide quantum dots nanoparticles targeted photothermal-chemotherapy for gastric cancer	5
Recent advances in nanoscale targeted therapy of HER2-positive breast cancer	5
A bispecific decoy receptor VEGFR-EGFR/Fc binding EGF-like ligands and VEGF shows potent antitumor efficacy	5
A topical formulation containing quercetin-loaded microcapsules protects against oxidative and inflammatory skin alterations triggered by UVB irradiation: enhancement of activity by microencapsulation	5
Demonstration of ultrasound-mediated therapeutic delivery of fibrin-targeted pioglitazone-loaded echogenic liposomes into the arterial bed for attenuation of peri-stent restenosis	4
Therapeutic effects of the gold nanoparticle on obesity-triggered neuroinflammation: a review	4
Trends in iron oxide nanoparticles: a nano-platform for theranostic application in breast cancer	4
Mucus- and pH-mediated controlled release of core-shell chitosan nanoparticles in the gastrointestinal tract for diabetes treatment	4
Alkoxy cyanoacrylate-based nanoparticles with stealth and brain-targeting properties	4
Effect of PEG anchor in PEGylation of folate-modified cationic liposomes with PEG-derivatives on systemic siRNA delivery into the Tumor	4
Combination treatment strategies with a focus on rosiglitazone and adriamycin for insulin resistant liver cancer	4
Epigenetic modulation: Research progress on histone acetylation levels in major depressive disorders	4
Study on lipid nanomicelles targeting placenta for the treatment of preeclampsia	4
Advances, challenge and prospects in cell-mediated nanodrug delivery for cancer therapy: a review	4
Protective effects of BP-1-102 against intracranial aneurysms-induced impairments in mice	4
Macrophage membrane biomimetic drug delivery system: for inflammation targeted therapy	4
Combinatorial delivery of Ribociclib and green tea extract mediated nanostructured lipid carrier for oral delivery for the treatment of breast cancer synchronising in silico, in vitro, a	4
Combination immunotherapy of oncolytic virus nanovesicles and PD-1 blockade effectively enhances therapeutic effects and boosts antitumour immune response	4