Journal of Drug Targeting

Article	Citations
A comprehensive review on the antiviral activities of chalcones	76
Carbon-based nanomaterials for targeted cancer nanotherapy: recent trends and future prospects	62
New advances in brain-targeting nano-drug delivery systems for Alzheimer's disease	44
A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: challenges analysis and recent advances	39
3D printing technology in healthcare: applications, regulatory understanding, IP repository and clinical trial status	38
Targetting ferroptosis for blood cell-related diseases	38
Manganese dioxide (MnO2) based nanomaterials for cancer therapies and theranostics	36
ABC transporters in breast cancer: their roles in multidrug resistance and beyond	35
Non-surgical osteoarthritis therapy, intra-articular drug delivery towards clinical applications	33
Empagliflozin alleviates myocardial I/R injury and cardiomyocyte apoptosis via inhibiting ER stress-induced autophagy and the PERK/ATF4/Beclin1 pathway	32
The relevant targets of anti-oxidative stress: a review	31
A γ-cyclodextrin-based metal–organic framework (γ-CD-MOF): a review of recent advances for drug delivery application	31
Active-site molecular docking of nigellidine with nucleocapsid–NSP2–MPro of COVID-19 and to human IL1R–IL6R and strong antioxidant role of Nigella sativa in experimental rats	29
Improving anti-tumour efficacy of PEGylated liposomal doxorubicin by dual targeting of tumour cells and tumour endothelial cells using anti-p32 CGKRK peptide	29
Niosomal formulation for antibacterial applications	28
An updated review on exosomes: biosynthesis to clinical applications	27
Mitochondria autophagy: a potential target for cancer therapy	27
Dual functional nanoparticles efficiently across the blood–brain barrier to combat glioblastoma via simultaneously inhibit the PI3K pathway and NKG2A axis	26
Nano drug delivery system reconstruct tumour vasculature for the tumour vascular normalisation	26
Genetically engineered exosomes display RVG peptide and selectively enrich a neprilysin variant: a potential formulation for the treatment of Alzheimer’s disease	25
Potential inhibitors of SARS-CoV-2: recent advances	25
Cationic liposome decorated with cyclic RGD peptide for targeted delivery of anti-STAT3 siRNA to melanoma cancer cells	21
Depleting microRNA-146a-3p attenuates lipopolysaccharide-induced acute lung injury via up-regulating SIRT1 and mediating NF-κB pathway	21
PEGylated DOX-coated nano graphene oxide as pH-responsive multifunctional nanocarrier for targeted drug delivery	21
MicroRNA-185 activates PI3K/AKT signalling pathway to alleviate dopaminergic neuron damage via targeting IGF1 in Parkinson’s disease	21

EGFR and anti-EGFR nanobodies: review and update	20
A mechanistic perspective on targeting bacterial drug resistance with nanoparticles	20
Advancements of compounds targeting Wnt and Notch signalling pathways in the treatment of inflammatory bowel disease and colon cancer	19
Methods for fabricating oxygen releasing biomaterials	19
The role of peptide-based therapeutics in oncotherapy	19
Nanoliposomes as drug delivery systems: safety concerns	19
Micro and nanorobot-based drug delivery: an overview	18
Immunotoxins and nanobody-based immunotoxins: review and update	18
HSP60 in cancer: a promising biomarker for diagnosis and a potentially useful target for treatment	18
Inhibition of microRNA-10b-5p up-regulates HOXD10 to attenuate Alzheimer’s disease in rats via the Rho/ROCK signalling pathway	17
Mesencephalic astrocyte-derived neurotrophic factor restores blood–brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway	17
Exosome-mediated transfer of circHIPK3 promotes trastuzumab chemoresistance in breast cancer	17
Erlotinib entrapped in cholesterol-depleting cyclodextrin nanoparticles shows improved antitumoral efficacy in 3D spheroid tumors of the lung and the liver	17
Progress in tumour-targeted drug delivery based on cell-penetrating peptides	16
Functionality of receptor targeted zinc-insulin quantum clusters in skin tissue augmentation and bioimaging	16
ROS1-positive non-small cell lung cancer (NSCLC): biology, diagnostics, therapeutics and resistance	16
Formulation development of tocopherol polyethylene glycol nanoengineered polyamidoamine dendrimer for neuroprotection and treatment of Alzheimer disease	16
Delivery of toll-like receptor agonists by complement C3-targeted liposomes activates immune cells and reduces tumour growth	15
ZIF-8 nanoparticles coated with macrophage-derived microvesicles for sustained, targeted delivery of dexamethasone to arthritic joints	15
Mitochondrial dysfunction and mitochondrion-targeted therapeutics in liver diseases	15
Delivery of RGD-modified liposome as a targeted colorectal carcinoma therapy and its autophagy mechanism	15
Targeting PRAS40: a novel therapeutic strategy for human diseases	15
Engineered anti-EGFRvIII targeted exosomes induce apoptosis in glioblastoma multiforme	15
New generation of viral nanoparticles for targeted drug delivery in cancer therapy	15
Mycobacterial ethambutol responsive genes and implications in antibiotics resistance	14
Significant metabolic alterations in patients with hepatitis B virus replication observed via serum untargeted metabolomics shed new light on hepatitis B virus infection	14
Role of exosomes in tumour growth, chemoresistance and immunity: state-of-the-art	14
Lipo-PEG nano-ocular formulation successfully encapsulates hydrophilic fluconazole and traverses corneal and non-corneal path to reach posterior eye segment	14
Efficient antiglioblastoma therapy in mice through doxorubicin-loaded nanomicelles modified using a novel brain-targeted RVG-15 peptide	14
TIGIT/PVR and LncRNA ANRIL dual-targetable PAMAM polymeric nanoparticles efficiently inhibited the hepatoma carcinoma by combination of immunotherapy and gene therapy	14
Innovative topical niosomal gel formulation containing diclofenac sodium (niofenac)	14
Light mediated drug delivery systems: a review	14
Effects and mechanisms of natural plant active compounds for the treatment of osteoclast-mediated bone destructive diseases	14
Tumour microenvironment-responsive nanoplatform based on biodegradable liposome-coated hollow MnO2 for synergistically enhanced chemotherapy and photodynamic therapy	13
A pH-Driven indomethacin-loaded nanomedicine for effective rheumatoid arthritis therapy by combining with photothermal therapy	13
Opportunity in nanomedicine to counter the challenges of current drug delivery approaches used for the treatment of malaria: a review	13
Silencing long non-coding RNA HNF1A-AS1 inhibits growth and resistance to TAM of breast cancer cells via the microRNA-363/SERTAD3 axis	13
Sirtuins as therapeutic targets for improving delayed wound healing in diabetes	12
Drug repurposing strategies and key challenges for COVID-19 management	12
Metformin combats obesity by targeting FTO in an m6A-YTHDF2-dependent manner	12
Recent advancement on albumin nanoparticles in treating lung carcinoma	12
Ultrasound image-guided gene delivery using three-dimensional diagnostic ultrasound and lipid-based microbubbles	12
Molecular and cellular biology of PCSK9: impact on glucose homeostasis	11
Biomimetic Ca2+ nanogenerator based on ions interference strategy for tumour-specific therapy	11
Macrophage targeted triptolide micelles capable of cGAS-STING pathway inhibition for rheumatoid arthritis treatment	11
Macrophage membrane biomimetic drug delivery system: for inflammation targeted therapy	11
Peptides-based therapy and diagnosis. Strategies for non-invasive therapies in cancer	10
New designed pH-responsive histidine-rich peptides with antitumor activity	10
Lymphatic targeting for therapeutic application using nanoparticulate systems	10
Cannabis as a potential compound against various malignancies, legal aspects, advancement by exploiting nanotechnology and clinical trials	10

Application of nanoparticles in drug delivery for the treatment of osteosarcoma: focussing on the liposomes	10
Effect of Malt-PEG-Abz@RSL3 micelles on HepG2 cells based on NADPH depletion and GPX4 inhibition in ferroptosis	10
Role of lipid nanocarriers for enhancing oral absorption and bioavailability of insulin and GLP-1 receptor agonists	10
Recent developments in nanoparticles for the treatment of diabetes	10
Biomimetic graphene oxide quantum dots nanoparticles targeted photothermal-chemotherapy for gastric cancer	10
Cetuximab-conjugated PLGA nanoparticles as a prospective targeting therapeutics for non-small cell lung cancer	10
Non-coding RNAs enhance the apoptosis efficacy of therapeutic agents used for the treatment of glioblastoma multiform	9
Smart delivery of epirubicin to cancer cells using aptamer-modified ferritin nanoparticles	9
Legumain protease-sheddable PEGylated, tuftsin-modified nanoparticles for selective targeting to tumour-associated macrophages	9
PVAT targets VSMCs to regulate vascular remodelling: angel or demon	9
Advances in autophagy as a target in the treatment of tumours	9
Tumour targeted polymer nanoparticles co-loaded with docetaxel and siCCAT2 for combination therapy of lung cancer	9
Current approaches and future prospects of nanofibers: a special focus on antimicrobial drug delivery	9
Improving protection effects of eucalyptol via carboxymethyl chitosan-coated lipid nanoparticles on hyperglycaemia-induced vascular endothelial injury in rats	9
Metformin protects cardiomyocytes against oxygen-glucose deprivation injury by promoting autophagic flux through AMPK pathway	9
Advances, challenge and prospects in cell-mediated nanodrug delivery for cancer therapy: a review	9
Application of nanotechnology in management and treatment of diabetic wounds	9
Recent highlights on Omicron as a new SARS-COVID-19 variant: evolution, genetic mutation, and future perspectives	8
Novel polysaccharide building hybrid nanoparticles: remodelling TAMs to target ERα-positive breast cancer	8
miR-1/133a and miR-206/133b clusters overcome HGF induced gefitinib resistance in non-small cell lung cancers with EGFR sensitive mutations	8
Emerging targeted therapeutic strategies for the treatment of triple-negative breast cancer	8
Combination therapy based on targeted nano drug co-delivery systems for liver fibrosis treatment: a review	8
Role of curcumin and its nanoformulations in the treatment of neurological diseases through the effects on stem cells	8
A topical formulation containing quercetin-loaded microcapsules protects against oxidative and inflammatory skin alterations triggered by UVB irradiation: enhancement of activity by microencapsulation	8
Characteristics of SARS-CoV2 that may be useful for nanoparticle pulmonary drug delivery	7
The role of miRNAs and lncRNAs in conferring resistance to doxorubicin	7
Progress in research and development of temozolomide brain-targeted preparations: a review	7
The ameliorating approach of nanorobotics in the novel drug delivery systems: a mechanistic review	7
Virulence-attenuated Salmonella engineered to secrete immunomodulators reduce tumour growth and increase survival in an autochthonous mouse model of breast cancer	7
Vascular priming with RRx-001 to increase the uptake and accumulation of temozolomide and irinotecan in orthotopically implanted gliomas	7
Nanotechnology revolutionises breast cancer treatment: harnessing lipid-based nanocarriers to combat cancer cells	7
Recent advances in nanoscale targeted therapy of HER2-positive breast cancer	7
Recent advances in hepatocellular carcinoma therapeutic strategies and imaging-guided treatment	7
Virus-like particle-based nanocarriers as an emerging platform for drug delivery	7
Fabrication techniques for the preparation of orally administered insulin nanoparticles	7
Angiopep-2 modified dual drug-loaded liposomes with brain targeting functionality mitigate Alzheimer’s disease-related symptoms in APP/PS-1 mice	7
Tumour targetable and microenvironment-responsive nanoparticles simultaneously disrupt the PD-1/PD-L1 pathway and MAPK/ERK/JNK pathway for efficient treatment of colorectal cancer	7
Olaparib@human serum albumin nanoparticles as sustained drug-releasing tumour-targeting nanomedicine to inhibit growth and metastasis in the mouse model of triple-negative breast cancer	7
Combinatorial delivery of Ribociclib and green tea extract mediated nanostructured lipid carrier for oral delivery for the treatment of breast cancer synchronising in silico, in vitro, a	7
Graphene quantum dots (GQDs) nanoarchitectonics for theranostic application in lung cancer	7
Poly-γ-glutamic acid coating polymeric nanoparticles enhance renal drug distribution and cellular uptake for diabetic nephropathy therapy	6
The activation of SIRT1 by resveratrol reduces breast cancer metastasis to lung through inhibiting neutrophil extracellular traps	6
Recent advances in novel miRNA mediated approaches for targeting breast cancer	6
EpCAM aptamer activated 5-FU-loaded PLGA nanoparticles in CRC treatment; in vitro and in vivo study	6
Trends in iron oxide nanoparticles: a nano-platform for theranostic application in breast cancer	6
Recent advances in curcumin-based nanoformulations in diabetes	6
Mucus- and pH-mediated controlled release of core-shell chitosan nanoparticles in the gastrointestinal tract for diabetes treatment	6
Effect of PEG anchor in PEGylation of folate-modified cationic liposomes with PEG-derivatives on systemic siRNA delivery into the Tumor	6
Albumin-encapsulated HSP90-PROTAC BP3 nanoparticles not only retain protein degradation ability but also enhance the antitumour activity of BP3 in vivo	6
Nanosystem functionalization strategies for prostate cancer treatment: a review	6
Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer	6
Detecting and targeting neurodegenerative disorders using electrospun nanofibrous matrices: current status and applications	6
Exploiting drug delivery systems for oral route in the peptic ulcer disease treatment	6
Dual-targeted colon-based integrated micelle drug delivery system for treatment of ulcerative colitis	6
A molecular signature of well-differentiated oral squamous cell carcinoma reveals a resistance mechanism to metronomic chemotherapy and novel therapeutic candidates	6
Emerging biologics for the treatment of pulmonary arterial hypertension	5
Therapeutic effects of the gold nanoparticle on obesity-triggered neuroinflammation: a review	5
A bispecific decoy receptor VEGFR-EGFR/Fc binding EGF-like ligands and VEGF shows potent antitumor efficacy	5
Novel anti-PD-L1 peptide selected from combinatorial phage library inhibits tumor cell growth and restores T-cell activity	5
Natural polymeric nanocarriers in malignant glioma drug delivery and targeting	5
The battle of lipid-based nanocarriers against blood-brain barrier: a critical review	5
Protective effects of BP-1-102 against intracranial aneurysms-induced impairments in mice	5
Impact of tumoral structure and bacterial species on growth and biodistribution of live bacterial therapeutics in xenografted tumours	5
Intradermal injection of icariin-HP-β-cyclodextrin improved traumatic brain injury via the trigeminal epineurium-brain dura pathway	5
Demonstration of ultrasound-mediated therapeutic delivery of fibrin-targeted pioglitazone-loaded echogenic liposomes into the arterial bed for attenuation of peri-stent restenosis	5
Therapeutic and diagnostic applications of carbon nanotubes in cancer: recent advances and challenges	5
Novel studies on Drosophila melanogaster model reveal the roles of JNK-Jak/STAT axis and intestinal microbiota in insulin resistance	5
Epigenetic modulation: Research progress on histone acetylation levels in major depressive disorders	5
Study on lipid nanomicelles targeting placenta for the treatment of preeclampsia	5
Alkoxy cyanoacrylate-based nanoparticles with stealth and brain-targeting properties	5
Perspectives of metformin use in endometrial cancer and other gynaecological malignancies	4
Microanatomy of the metabolic associated fatty liver disease (MAFLD) by single-cell transcriptomics	4
Reduction of systemic exposure and side effects by intra-articular injection of anti-inflammatory agents for osteoarthritis: what is the safer strategy?	4
Combination treatment strategies with a focus on rosiglitazone and adriamycin for insulin resistant liver cancer	4
Multifunctional metal complex-based gene delivery for tumour immune checkpoint blockade combination therapy	4
Research advances in immune checkpoint drugs for non-small cell lung cancer	4
Nanoparticles toxicity: an overview of its mechanism and plausible mitigation strategies	4
Nanocarrier-based co-delivery approaches of chemotherapeutics with natural P-glycoprotein inhibitors in the improvement of multidrug resistance cancer therapy	4
Targeting cellular energy metabolism- mediated ferroptosis by small molecule compounds for colorectal cancer therapy	4
Targeted therapy of tumour microenvironment by gold nanoparticles as a new therapeutic approach	4

microRNAs: critical targets for treating rheumatoid arthritis angiogenesis	4
A platelet-cloaking tetramethylprazine-loaded microemulsion for improved therapy of myocardial ischaemia/reperfusion injury	4
Transdermal delivery of celecoxib and α-linolenic acid from microemulsion-incorporated dissolving microneedles for enhanced osteoarthritis therapy	4
Signalling in pancreatic cancer: from pathways to therapy	4
Novel strategies for the fight of Alzheimer’s disease targeting amyloid-β protein	4
Emerging trends in aggregation induced emissive luminogens as bacterial theranostics	3
Efficient drug delivery by novel cell-penetrating peptide derived from Midkine, with two heparin binding sites braced by a length-specific helix	3
Her-2-directed systemic delivery of fatty acid synthase (FASN) siRNA with novel liposomal carrier systems in the breast cancer mouse model	3
Histone deacetylase 9 inhibition upregulates microRNA-92a to repress the progression of intracranial aneurysm via silencing Bcl-2-like protein 11	3
Nanotechnology-based photo-immunotherapy: a new hope for inhibition of melanoma growth and metastasis	3
Bone morphogenetic protein (BMP)9 in cancer development: mechanistic, diagnostic, and therapeutic approaches?	3
Targeted treatment of atherosclerosis with protein–polysaccharide nanoemulsion co-loaded with photosensitiser and upconversion nanoparticles	3
Silver nanoparticle-based drug delivery systems in the fight against COVID-19: enhancing efficacy, reducing toxicity and improving drug bioavailability	3
A paradigm use of monoclonal antibodies-conjugated nanoparticles in breast cancer treatment: current status and potential approaches	3
Evaluating the reliability of tumour spheroid-on-chip models for replicating intratumoural drug delivery: considering the role of microfluidic parameters	3
Advancing biofilm management through nanoformulation strategies: a review of dosage forms and administration routes	3
Research progress of exosomes as drug carriers in cancer and inflammation	3
Pressure-driven accumulation of Mn-doped mesoporous silica nanoparticles containing 5-aza-2-deoxycytidine and docetaxel at tumours with a dry cupping device	3
Black phosphorus nanoparticles for dual therapy of non-small cell lung cancer	3
Hyaluronic acid prodrug micelles for tumour therapy	3
Prominent and emerging anti-diabetic molecular targets	3
Nanoreactor activated in situ for starvation-chemodynamic therapy of breast cancer	3
Desmethoxycurcumin aids IFNα’s anti-HBV activity by antagonising CRYAB reduction and stabilising IFNAR1 protein	3
Nano-composite hydrogels of Cu-Apa micelles for anti-vasculogenic mimicry	3
A multi-storey DNA nanostructure containing doxorubicin and AS1411 aptamer for targeting breast cancer cells	3
The combination of linagliptin and metformin rescues bone loss in type 2 diabetic osteoporosis	3