Molecular Biology of the Cell

Article	Citations
Preprint Highlight: Multiplexed bioluminescence microscopy via phasor analysis	62
Preprint Highlight: Mitotic clustering of pulverized chromosomes from micronuclei	46
Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2	40
Mga2-mediated transcription supports mitotic nuclear expansion under lipid saturation conditions in stearoyl-CoA desaturase Ole1 mutant	38
Suppression of cofilin-1 promotes invasion in 3D hyaluronic acid matrices by promoting actin-based protrusions	37
Nonmuscle myosin IIA (NMIIA) regulates anisotropic cell tension to maintain the hexagonal packing of mouse lens meridional row cells	37
Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence	32
Sec18 binds the tethering/SM complex HOPS to engage the Qc-SNARE for membrane fusion	31
Hydrostatic pressure from basal side promotes cancer proliferation, enhances migration, and alters cell polarity: A model of the effects of interstitial fluid pressure in tumor microenvironment	31
Mitotic spindle membranes	31
David Baltimore and the advent of eukaryotic RNA-binding proteins	28
Systematic evaluation of tools for auxin-inducible protein degradation in budding yeast	27
Image-based discrimination of the early stages of mesenchymal stem cell differentiation	27
Landmarks in the discovery of a role for actin in cell locomotion	27
Distinct signaling mechanisms and proteome phenotypes are elicited by compartment-specific genetic defects of copper homeostasis	27
p97/VCP Promotes the Recycling of Endocytic Cargo	27
The outer kinetochore components KNL-1 and Ndc80 complex regulate axon and neuronal cell body positioning in the C. elegans nervous system	26
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic	26
After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells	26
A role for Keratin 17 in Rac1-mediated DNA damage response in keratinocytes	25
STMND1 is a phylogenetically ancient stathmin which localizes to motile cilia and exhibits nuclear translocation that is inhibited when soluble tubulin concentration increases	25
Bacterial ecology in confined and spatially structured in vitro habitats	25
Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia	25
Actin contraction controls nuclear blebbing and rupture independent of actin confinement	24
Preprint Highlight: Self‐supervised deep learning encodes high-resolution features of protein subcellular localization	23

Preprint Highlight: Dynamic interplay of protrusive microtubule and contractile actomyosin forces drive tissue extension	23
Tubulin acetylation deficiency promotes axonemal turnover and increases cytoplasmic microtubules	23
From pipette to palette: Bridging science and art at MBoC	23
Delamination of epithelia induced by air–liquid interfaces	22
Preprint Highlight: Contractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis	22
Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility	22
Preprint Highlight: Vimentin intermediate filaments organize organellar ER architecture in response to stress	22
A modified motor-clutch model reveals that neuronal growth cones respond faster to soft substrates	21
Calcium-binding Cab45 regulates the polarized apical secretion of soluble proteins in epithelial cells	21
LYSET facilitates integration of both the N- and C-terminal transmembrane helices/cytoplasmic domains of GlcNAc-1-phosphotransferase	21
Insights into the role of Nup62 and Nup93 in assembling cytoplasmic ring and central transport channel of the nuclear pore complex	21
The initiation and early development of the tubulin-containing cytoskeleton in the human parasite Toxoplasma gondii	21
Big1 is a newly identified autophagy regulator that is critical for a fully functional V-ATPase	21
Osh-dependent and -independent Regulation of PI4P Levels During Polarized Growth ofSaccharomyces cerevisiae	21
EHD2 regulates plasma membrane integrity and downstream insulin receptor signaling events	21
Membrane lipids couple synaptotagmin to SNARE-mediated granule fusion in insulin-secreting cells	20
HSPA8 inhibitors augment cancer chemotherapeutic effectiveness via potentiating necroptosis	20
FHOD-1 and profilin protect sarcomeres against contraction-induced deformation> in C. elegans	20
Scaling of biosynthesis and metabolism with cell size	20
A mathematical model of calcium signals around laser-induced epithelial wounds	20
Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins	20
The nuclear isoforms of the Fragile X mental retardation RNA-binding protein associate with genomic DNA bridges	19
Characterization of Orsay virus replication intermediates in Caenorhabditis elegans reveals links to antiviral RNA interference	19
Orchestrating nonmuscle myosin II filament assembly at the onset of cytokinesis	19
Cell type- and transcription-independent spatial proximity between enhancers and promoters	19
Heterologous expression of Dictyostelium discoideum NE81 in mouse embryo fibroblasts reveals conserved mechanoprotective roles of lamins	19
A system for high-throughput axonal imaging of induced pluripotent stem cell-derived human i 3 Neurons	19
Cytoplasmic preassembly of the flagellar outer dynein arm complex in Trypanosoma brucei	19
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding	19
DAmFRET measures saturating concentrations and toxicities of protein phase transitions in vivo	19
The biophysical mechanism of mitochondrial pearling	19
Lgd regulates ESCRT-III complex accumulation at multivesicular endosomes to control intralumenal vesicle formation	18
Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division	18
Intracellular diffusion in the cytoplasm increases with cell size in fission yeast	18
Atypical and distinct microtubule radial symmetries in the centriole and the axoneme of Lecudina tuzetae	18
LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis	18
Regulation of misfolded protein aggregation and degradation by SUMOylation in budding yeast	18
Serotonin 5-HT7 receptor slows down the Gs protein: a single molecule perspective	18
Cell segregation via differential collision modes between heterotypic cell populations	17
Mechanisms underlying Myosin 10′s contribution to the maintenance of mitotic spindle bipolarity	17
Plectin linkages are mechanosensitive and required for the nuclear piston mechanism of three-dimensional cell migration	17
Practical guide to fluorescence lifetime imaging microscopy	17
Interaction of the sorting nexin 25 homologue Snazarus with Rab11 balances endocytic and secretory transport and maintains the ultrafiltration diaphragm in nephrocytes	16
The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential	16
The Kinesin-14 tail: Dual microtubule binding domains drive spindle morphogenesis through tight microtubule cross-linking and robust sliding	16
Preexisting tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia	16
ARHGAP18 complexes with both YAP and Merlin and is required for basal actin bundles.	16
Ehg1/May24 stabilizes yeast amino acid permease by facilitating its localization to lipid rafts under high hydrostatic pressure	16
MotiQ: an open-source toolbox to quantify the cell motility and morphology of microglia	16
Regulation of membrane scission in yeast endocytosis	16

Visualization of the three-dimensional structure of the human centromere in mitotic chromosomes by superresolution microscopy	16
Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells	16
YeastSAM: A deep learning model for accurate segmentation of yeast cells	16
Multiple tethers of organelle contact sites are involved in α-synuclein toxicity in yeast	16
The SNARE-associated protein Sft2 functions in Imh1-mediated SNARE recycling transport upon ER stress	16
Spatiotemporal analysis of F-actin polymerization with micropillar arrays reveals synchronization between adhesion sites	16
Nucleoli in epithelial cell collectives respond to tumorigenic, spatial, and mechanical cues	16
Breaking the rules of cell biology: Lessons from the liver's exceptional regenerative capacity	16
Preprint Highlight: Real-time denoising of fluorescence time-lapse imaging enables high-sensitivity observations of biological dynamics beyond the shot-noise limit	16
Tools for live-cell imaging of cytoskeletal and nuclear behavior in the unconventional yeast, Aureobasidium pullulans	15
Correction for Angiotensin II down-regulates nephrinAkt signaling and induces podocyte injury: role of c-Abl	15
Distinct peroxisome populations differentially respond to alcohol-associated hepatic injury	15
Outer-arm dynein light chain LC1 is required for normal motor assembly kinetics, ciliary stability, and motility	15
Actin and vimentin jointly control cell viscoelasticity and compression stiffening	15
p115RhoGEF activates RhoA to support tight junction maintenance and remodeling	15
Activation of the ChvG–ChvI pathway promotes survival during cell wall stress in Agrobacterium tumefaciens	14
The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration	14
Endothelial tip/stalk cell selection requires BMP9-induced βIV-spectrin expression during sprouting angiogenesis	14
Antiparallel microtubule bundling supports KIF15-driven mitotic spindle assembly	14
Remodeling of cytoskeleton, chromatin, and gene expression during mechanical rejuvenation of aged human dermal fibroblasts	14
Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization	14
Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis	14
2022 ASCB Annual Meeting abstracts	14
FOXO nuclear shuttling dynamics are stimulus-dependent and correspond with cell fate	14
Modification of the neck-linker of KIF18A alters Microtubule subpopulation preference	14
Neuronal membrane proteasome-derived peptides modulate NMDAR-dependent neuronal signaling to promote changes in gene expression	14
Innate immune cross-talk: The central role of neutrophils and macrophages in ANCA-associated vasculitis	13
A role for the kinetochore protein, NUF2, in ribosome biogenesis	13
Loss of CHMP2A implicates an ordered assembly of ESCRT-III proteins during cytokinetic abscission	13
WAVE facilitates polarized E-cadherin transport	13
A cross-species analysis of cell wall mechanosensors	13
Celebrating women in academia and addressing underrepresentation	13
Temporal control of contact site formation reveals a relationship between mitochondrial division and Num1-mediated mitochondrial tethering	13
The role of neurofilament transport in the radial growth of myelinated axons	13
WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration	13
Drosophila Fog/Cta and T48 pathways have overlapping and distinct contributions to mesoderm invagination	13
Loss of intermicrovillar adhesion factor CDHR2 impairs basolateral junctional complexes in transporting epithelia	13
Complex state transitions of the bacterial cell division protein FtsZ	13
Imaging-based screen identifies novel natural compounds that perturb cell and chloroplast division in Chlamydomonas reinhardtii	13
The mammalian class IX myosins Myo9a and Myo9b use different cellular actin assemblies for force production and regulation of Rho activity	13
Septin organization is regulated by the Gpa1 ubiquitination domain and endocytic machinery during the yeast pheromone response	13
Phospholipase D1 produces phosphatidic acid at sites of secretory vesicle docking and fusion	13
Loss of negative regulation by HDAC1 and REST contributes to MAD1 overexpression in breast cancer	12
Preprint Highlight: The novel Rab5 effector FERRY links early endosomes with the translation machinery	12
Role of Gα–MAPK interaction in mating of Saccharomyces cerevisiae	12
Recruitment of the lipid kinase Mss4 to the meiotic spindle pole promotes prospore membrane formation in Saccharomyces cerevisiae	12
Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells	12
Polymer dynamics of Alp7A reveals how two critical concentrations govern assembly of dynamically unstable actin-like proteins	12
The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation	12
Preprint Highlight: Deciphering the tumor-specific immunopeptidome in vivo with genetically engineered mouse models	12
The RhoGAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle	12
Transient PP2A SIP complex localization to mitotic SPBs for SIN inhibition is mediated solely by the Csc1 FHA domain	12
Nkd1 functions downstream of Axin2 to attenuate Wnt signaling	12
Independence of centromeric and pericentromeric chromatin stability on CCAN components	12
Preprint Highlight: Probing the rules of cell coordination in live tissues by interpretable machine learning based on graph neural networks	12
The TOG5 domain of CKAP5 is required to interact with F-actin and promote microtubule advancement in neurons	12
RAD51 regulates eukaryotic chromatin motions in the absence of DNA damage	12
Dynein-dependent collection of membranes defines the architecture and position of microtubule asters in isolated, geometrically confined volumes of cell-free extracts	12
Results from the MBoC Preprint Highlight experiment	11
Recruitment of PI4KIIIβ to the Golgi by ACBD3 is dependent on an upstream pathway of a SNARE complex and golgins	11
Identification of a Golgi-localized peptide reveals a minimal Golgi-targeting motif	11
Polymer models reveal how chromatin modification can modulate force at the kinetochore	11
A new subset of mitochondrial-derived vesicles perform inter-mitochondrial communications	11
Nucleolar structure connects with global nuclear organization	11
Preprint Highlight: PGC1α regulates the endothelial response to fluid shear stress via telomerase reverse transcriptase control of heme oxygenase‐1	11
Strained actin binding by the Prickle2 LIM domains and their regulation in the full-length protein	11
Systematic analysis of microtubule plus-end networks defines EB-cargo complexes critical for mitosis in budding yeast	11
CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis	11
Fission yeast Pdk1 kinase regulates cytokinesis and eisosomes	11
Preprint Highlight: LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia via Transcription Factor E3 Inhibition	11
Linear Z-line-like alignment of capping protein in obliquely striated muscle of the nematode C. elegans suggests that dense bodies are not equivalent to	11
RanBP2-dependent SUMOylation of G3BP2 inhibits formation, and promotes disassembly, of stress granules	11
In vivo imaging reveals independent intraflagellar transport of the nexin–dynein regulatory complex subunits DRC2 and DRC4	11
Mutation of the PEBP-like domain of the mitoribosomal MrpL35/mL38 protein results in production of nascent chains with impaired capacity to assemble into OXPHOS complexes	11
How many authors does it take to publish a high profile or classic paper?	11
A role for Nup153 in nuclear assembly reveals differential requirements for targeting of nuclear envelope constituents	11
Scaling of nuclear numbers and their spatial arrangement in skeletal muscle cell size regulation	11
The roles of yeast formins and their regulators Bud6 and Bil2 in the pheromone response	11
Quantitative analysis of morphogenesis and growth dynamics in an obligate intracellular bacterium	11
Growth cone macropinocytosis of neurotrophin receptor and neuritogenesis are regulated by neuron navigator 1	11

A novel tool for the unbiased characterization of epithelial monolayer development in culture	10
Maximizing Access to Cell Biology for PEERS: Retracting the term minority in favor of a more inclusive lexicon	10
Preprint Highlight: Detyrosination enrichment on microtubule subsets is established by the interplay between a stochastically acting enzyme and microtubule stability	10
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation	10
A methodology for specific disruption of microtubule polymerization into dendritic spines	10
Diffusion within the synaptonemal complex can account for signal transduction along meiotic chromosomes	10
VAC14 oligomerization is essential for the function of the FAB1/PIKfyve–VAC14–FIG4 complex	10
Preprint Highlight: Actomyosin cables position cell cohorts during Drosophila germband retraction by entraining their morphodynamic and mechanical properties	10
Breaking the annotation barrier: An initial subcellular localization atlas of Giardia ’s hypothetical and conserved hypothetical proteins provides a reso	10
A dedicated cytoplasmic container collects extrachromosomal DNA away from the mammalian nucleus	10
Automated segmentation of soft X-ray tomography: Native cellular structure with submicron resolution at high-throughput for whole-cell quantitative imaging in yeast	10
Trafficking of K63-polyubiquitin–modified membrane proteins in a macroautophagy-independent pathway is linked to ATG9A	10
Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants	10
FAZ assembly in bloodstream form Trypanosoma brucei requires kinesin KIN-E	10
Superresolution microscopy reveals actomyosin dynamics in medioapical arrays	10
Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization	10
Nanotopography modulates cytoskeletal organization and dynamics during T cell activation	10
Plasma membrane protrusions mediate host cell–cell fusion induced by Burkholderia thailandensis	10
Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei	10
Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates	10
Traveling-wave chemotaxis of neutrophil-like HL-60 cells	10
Dishevelled controls bulk cadherin dynamics and the stability of individual cadherin clusters during convergent extension	10
Basal autophagy during meiotic prophase I is required for accurate chromosome segregation in Drosophila oocytes and declines during oocyte aging	10
The lipid droplet protein Jabba promotes actin remodeling downstream of prostaglandin signaling during Drosophila oogenesis	10
Preprint Highlight: Transcriptomic changes highly similar to Alzheimer's disease are observed in a subpopulation of individuals during normal brain aging	10
Did axons evolve by activating cytokinesis during interphase? A hypothesis on the origin of neurons	9
Solo regulates the localization and activity of LARG for actin cytoskeletal remodeling in cell-substrate adhesions	9
Preprint Highlight: Disruption of lactate metabolism in the peripheral nervous system leads to motor selective deficits	9
Molecular features and clinical significance of cancer-associated fibroblasts in colorectal cancer	9
Evidence for novel mechanisms that control cell-cycle entry and cell size	9
Membrane stretching activates calcium permeability of a putative channel Pkd2 during fission yeast cytokinesis	9
Enabled primarily controls filopodial morphology, not actin organization, in the TSM1 growth cone inDrosophila	9
Dysregulation of ceramide metabolism causes phytoceramide-dependent induction of the unfolded protein response	9
Membrane fusion by Drosophila atlastin does not require GTP hydrolysis	9
Ultrastructure of COPII vesicle formation in yeast characterized by correlative light and electron microscopy	9
Michael Patrick Sheetz, 1946–2025, a devotee of and major contributor to membrane and cytoskeletal biology	9
M phase–specific generation of supernumerary centrioles in cancer cells	9
Powering morphogenesis: multiscale challenges at the interface of cell adhesion and the cytoskeleton	9
Three types of actomyosin rings within a common cytoplasm exhibit distinct modes of contractility	9
Inositol 1, 4, 5-trisphosphate receptor is required for spindle assembly in Xenopus oocytes	9
Inhibition of the chromatin remodeling factor NURF rescued sterility by a clinic variant of NuRD	9
VAMP5 promotes Fcγ receptor-mediated phagocytosis and regulates phagosome maturation in macrophages	9
Correction for Article Title “The laforin-malin complex, involved in Lafora disease, promotes the incorporation of K63-linked ubiquitin chains into AMP-activated protein kinase beta subunits”.	9
Cilia.Pro database of ciliary proteins from vertebrates, Chlamydomonas , and Caenorhabditis	9
Large-scale mapping of positional changes of hypoxia-responsive genes upon activation	9
Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids	9
Preprint Highlight: Learning orientation-invariant representations enables accurate and robust morphologic profiling of cells and organelles	9
AP-4 regulates neuronal lysosome composition, function, and transport via regulating export of critical lysosome receptor proteins at the trans-Golgi network	9
A PACAP-activated network for secretion requires coordination of Ca 2+ influx and Ca 2+ mobilizati	9
FAP20 is required for flagellum assembly in Trypanosoma brucei	9
The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes	9
Differentiation-dependent changes in lamin B1 dynamics and lamin B receptor localization	9
Septins associate with AP-3 to support trafficking to the vacuole/lysosome in yeast	9
Lipid droplets are rigid and physically suppress phagocytosis, unless cell compression or stretching activates actomyosin	8
Parkinson disease–associated toxic exposures selectively up-regulate vesicular glutamate transporter vGlut2 in a model of human cortical neurons	8
The unfolded protein response of the endoplasmic reticulum supports mitochondrial biogenesis by buffering nonimported proteins	8
MRE11-independent effects of Mirin on mitochondrial DNA integrity and cellular immune responses	8
Ras-mediated activation of mTORC2 promotes breast epithelial cell migration and invasion	8
Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA	8
The myosin chaperone UNC-45 has an important role in maintaining the structure and function of muscle sarcomeres during adult aging	8
Novel cryo-tomography workflow reveals nanometer-scale responses of epithelial cells to matrix stiffness and dimensionality	8
The C-terminus of α-Synuclein Regulates its Dynamic Cellular Internalization by Neurexin 1β	8
Med13 is required for efficient P-body recruitment and autophagic degradation of Edc3 following nitrogen starvation	8
Isoform-specific phosphorylation of axonemal dynein heavy chains	8
Preprint Highlight: The mechanosensitive ion channel Piezo mediates Rho activation and actin stress fibre formation in Drosophila nephrocytes	8
The DEAD-box RNA helicase DDX28 suppresses cell migration and 3D growth and invasion in MDA-MB-231 cells by altering bioenergetics	8
Functional fluorescence labeling of actins in live-cell system using engineered split-GFP technology	8
Quantitative fluorescence emission anisotropy microscopy for implementing homo–fluorescence resonance energy transfer measurements in living cells	8
Regulation of p65 nuclear localization and chromatin states by compressive force	8
Endosome maturation during ER stress relies on the ubiquitin-binding domain of histone deacetylase 6	8
SEL1L regulates ER homeostasis in Sertoli cells but is dispensable for their function	8
SPAK-dependent cotransporter activity mediates capillary adhesion and pressure during glioblastoma migration in confined spaces	8
Myosin F controls actin organization and dynamics in Toxoplasma gondii	8
Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif	8
The [PSI+] prion modulates cytochrome c oxidase deficiency caused by deletion of COX12	8
Remarkable chromosomes and karyotypes: A top 10 list	8
Mechanical strategies supporting growth and size diversity in Filamentous Fungi	8
On the inference of ERK signaling dynamics from protein biosensor measurements	8
A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase	8