Molecular Biology of the Cell

Papers
(The TQCC of Molecular Biology of the Cell is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
SuperPlotsOfData—a web app for the transparent display and quantitative comparison of continuous data from different conditions86
Nuclear body phase separation drives telomere clustering in ALT cancer cells77
Predicting cell health phenotypes using image-based morphology profiling64
Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics62
Direct evidence that tumor cells soften when navigating confined spaces61
Electron tomography reveals aspects of spindle structure important for mechanical stability at metaphase57
BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins57
Occludin and tricellulin facilitate formation of anastomosing tight-junction strand network to improve barrier function53
Mechanical stress triggers nuclear remodeling and the formation of transmembrane actin nuclear lines with associated nuclear pore complexes47
Open-source deep-learning software for bioimage segmentation46
Collagen, stiffness, and adhesion: the evolutionary basis of vertebrate mechanobiology45
Roles of leader and follower cells in collective cell migration44
The burden of service for faculty of color to achieve diversity and inclusion: the minority tax43
Lipid and protein dynamics that shape nuclear envelope identity42
New twists in actin–microtubule interactions41
Revised subunit order of mammalian septin complexes explains their in vitro polymerization properties41
Cooperation of the IFT-A complex with the IFT-B complex is required for ciliary retrograde protein trafficking and GPCR import40
XK is a partner for VPS13A: a molecular link between Chorea-Acanthocytosis and McLeod Syndrome40
Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion39
Reorganization of budding yeast cytoplasm upon energy depletion38
Dynamic actin-mediated nano-scale clustering of CD44 regulates its meso-scale organization at the plasma membrane37
Plasma membrane tension regulates eisosome structure and function35
Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex35
Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization32
Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons31
Microtubule dynamics at low temperature: evidence that tubulin recycling limits assembly31
Msp1 cooperates with the proteasome for extraction of arrested mitochondrial import intermediates31
Initiation and disassembly of filopodia tip complexes containing VASP and lamellipodin31
Masters of asymmetry – lessons and perspectives from 50 years of septins31
Long-range mechanical coupling of cells in 3D fibrin gels30
Arf1 directly recruits the Pik1-Frq1 PI4K complex to regulate the final stages of Golgi maturation30
Novel fibrillar structure in the inversin compartment of primary cilia revealed by 3D single-molecule superresolution microscopy29
High-throughput gene screen reveals modulators of nuclear shape29
Epithelial tissue geometry directs emergence of bioelectric field and pattern of proliferation29
The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy29
DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy29
Unraveling the mysteries of centriolar satellites: time to rewrite the textbooks about the centrosome/cilium complex28
Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb27
Freedom of assembly: metabolic enzymes come together27
Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin kinase 226
Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration26
Dynactin p150 promotes processive motility of DDB complexes by minimizing diffusional behavior of dynein25
Three-dimensional niche stiffness synergizes with Wnt7a to modulate the extent of satellite cell symmetric self-renewal divisions25
Angiomotin links ROCK and YAP signaling in mechanosensitive differentiation of neural stem cells25
Diversity through equity and inclusion: The responsibility belongs to all of us25
Endoplasmic reticulum stress causes insulin resistance by inhibiting delivery of newly synthesized insulin receptors to the cell surface25
Nonmuscle myosin-2 contractility-dependent actin turnover limits the length of epithelial microvilli24
Mitochondria regulate intestinal stem cell proliferation and epithelial homeostasis through FOXO24
Regulation of meiotic progression by Sertoli-cell androgen signaling24
AnnotatorJ: an ImageJ plugin to ease hand annotation of cellular compartments24
Violin SuperPlots: visualizing replicate heterogeneity in large data sets24
FOXM1 nuclear transcription factor translocates into mitochondria and inhibits oxidative phosphorylation23
R-loops at centromeric chromatin contribute to defects in kinetochore integrity and chromosomal instability in budding yeast23
Yeast synaptobrevin, Snc1, engages distinct routes of postendocytic recycling mediated by a sorting nexin, Rcy1-COPI, and retromer22
Centrosome–nuclear axis repositioning drives the assembly of a bipolar spindle scaffold to ensure mitotic fidelity22
Peroxisomes exhibit compromised structure and matrix protein content in SARS-CoV-2-infected cells22
DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division22
Mechanistic insights into actin-driven polarity site movement in yeast22
Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion22
Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB1021
Robust classification of cell cycle phase and biological feature extraction by image-based deep learning21
An updated SYSCILIA gold standard (SCGSv2) of known ciliary genes, revealing the vast progress that has been made in the cilia research field21
Early and nonredundant functions of dynamin isoforms in clathrin-mediated endocytosis21
Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription21
Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes21
Dynamic actin cross-linking governs the cytoplasm’s transition to fluid-like behavior21
Quantifying topography-guided actin dynamics across scales using optical flow20
Integrin-linked kinase tunes cell–cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ120
Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation20
Beyond Langmuir: surface-bound macromolecule condensates20
Regulation of NRF1, a master transcription factor of proteasome genes: implications for cancer and neurodegeneration20
A role for keratins in supporting mitochondrial organization and function in skin keratinocytes20
Practical method for superresolution imaging of primary cilia and centrioles by expansion microscopy using an amplibody for fluorescence signal amplification20
Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments20
PLK1 is required for chromosome compaction and microtubule organization in mouse oocytes20
The LINC complex is required for endothelial cell adhesion and adaptation to shear stress and cyclic stretch20
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis20
WAVE1 and WAVE2 have distinct and overlapping roles in controlling actin assembly at the leading edge19
Mrx6 regulates mitochondrial DNA copy number inSaccharomyces cerevisiaeby engaging the evolutionarily conserved Lon protease Pim119
DynaMorph: self-supervised learning of morphodynamic states of live cells19
Cellular self-organization: generating order from the abyss19
The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A19
Cell-type-specific mechanical response and myosin dynamics during retinal lens development in Drosophila19
Novel cytokinetic ring components drive negative feedback in cortical contractility19
Ubiquitin–proteasome-mediated cyclin C degradation promotes cell survival following nitrogen starvation19
Catalysts for change: the cellular neurobiology of psychedelics19
The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism19
Multisite EGFR phosphorylation is regulated by adaptor protein abundances and dimer lifetimes19
Importin binding mediates the intramolecular regulation of anillin during cytokinesis18
Hsf1 activation by proteotoxic stress requires concurrent protein synthesis18
Endoplasmic reticulum transmembrane protein TMTC3 contributes to O-mannosylation of E-cadherin, cellular adherence, and embryonic gastrulation18
Quantifying the roles of space and stochasticity in computer simulations for cell biology and cellular biochemistry18
Multiple C2 domain–containing transmembrane proteins promote lipid droplet biogenesis and growth at specialized endoplasmic reticulum subdomains18
Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division18
The ER protein Ema19 facilitates the degradation of nonimported mitochondrial precursor proteins18
TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K–C2α-, and INPP4B-mediated phosphoinositide conversions18
The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate18
Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants18
DNA content contributes to nuclear size control inXenopus laevis18
Fascin-induced actin protrusions are suppressed by dendritic networks in giant unilamellar vesicles18
Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-217
Formation of the B9-domain protein complex MKS1–B9D2–B9D1 is essential as a diffusion barrier for ciliary membrane proteins17
Preserving genome integrity in human cells via DNA double-strand break repair17
PP1 promotes cyclin B destruction and the metaphase–anaphase transition by dephosphorylating CDC2017
Proteomic analysis of desmosomes reveals novel components required for epidermal integrity17
The N- or C-terminal cytoplasmic regions of P4-ATPases determine their cellular localization17
The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells17
Roles for L o microdomains and ESCRT in ER stress-induced lipid droplet microautophagy in budding yeast16
Kinetochore proteins suppress neuronal microtubule dynamics and promote dendrite regeneration16
A septin-Hof1 scaffold at the yeast bud neck binds and organizes actin cables16
PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis16
Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT16
SUMO paralogue–specific functions revealed through systematic analysis of human knockout cell lines and gene expression data16
Protein turnover dynamics suggest a diffusion-to-capture mechanism for peri-basal body recruitment and retention of intraflagellar transport proteins16
Roles for ELMOD2 and Rootletin in ciliogenesis16
Dynamin 2 interacts with α-actinin 4 to drive tumor cell invasion16
ESCRT-III and ER–PM contacts maintain lipid homeostasis15
An update on genetically encoded lipid biosensors15
Asymmetric Rab activation of vacuolar HOPS to catalyze SNARE complex assembly15
Mgr2 regulates mitochondrial preprotein import by associating with channel-forming Tim23 subunit15
Elevating PI3P drives select downstream membrane trafficking pathways15
The HIF target ATG9A is essential for epithelial barrier function and tight junction biogenesis15
Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch15
β-catenin-mediated Wnt signal transduction proceeds through an endocytosis-independent mechanism15
Calcium spikes accompany cleavage furrow ingression and cell separation during fission yeast cytokinesis15
Osmosensing by WNK Kinases15
Superresolution light microscopy of the Drosophila histone locus body reveals a core–shell organization associated with expression of replication–dependent histone genes14
The prion-like domain of Fused in Sarcoma is phosphorylated by multiple kinases affecting liquid- and solid-phase transitions14
Fibroblast to myofibroblast transition is enhanced by increased cell density14
Arf1 orchestrates Rab GTPase conversion at the trans-Golgi network14
Cytoplasmic streaming drifts the polarity cue and enables posteriorization of theCaenorhabditis eleganszygote at the side opposite of sperm entry14
The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis14
SARS-CoV-2 down-regulates ACE2 through lysosomal degradation14
Matrix stiffness-sensitive long noncoding RNA NEAT1 seeded paraspeckles in cancer cells14
Unconventional endocytosis and trafficking of transferrin receptor induced by iron14
β-actin contributes to open chromatin for activation of the adipogenic pioneer factor CEBPA during transcriptional reprograming13
The Hec1/Ndc80 tail domain is required for force generation at kinetochores, but is dispensable for kinetochore–microtubule attachment formation and Ska complex recruitment13
Whole-genome screen identifies diverse pathways that negatively regulate ciliogenesis13
Hydrogen peroxide induces Arl1 degradation and impairs Golgi-mediated trafficking13
RTN4B interacting protein FAM134C promotes ER membrane curvature and has a functional role in autophagy13
VPS13D interacts with VCP/p97 and negatively regulates ER- mitochondrial interactions13
APC regulation of ESRP1 and p120-catenin isoforms in colorectal cancer cells13
Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase13
PxdA interacts with the DipA phosphatase to regulate peroxisome hitchhiking on early endosomes13
Whi5 is diluted and protein synthesis does not dramatically increase in pre-Start G113
Diffusion of kinesin motors on cargo can enhance binding and run lengths during intracellular transport12
Synergistic factors control kinase–phosphatase organization in B-cells engaged with supported bilayers12
Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control12
Atg15 in Saccharomyces cerevisiae consists of two functionally distinct domains12
Exploiting differential effects of actomyosin contractility to control cell sorting among breast cancer cells12
We need to address ableism in science12
Long-term mitochondrial stress induces early steps of Tau aggregation by increasing reactive oxygen species levels and affecting cellular proteostasis12
Microtubule-dependent pushing forces contribute to long-distance aster movement and centration inXenopus laevisegg extracts12
The Borealin dimerization domain interacts with Sgo1 to drive Aurora B–mediated spindle assembly12
Flexible pivoting of dynamin pleckstrin homology domain catalyzes fission: insights into molecular degrees of freedom11
Load adaptation by endocytic actin networks11
Formins specify membrane patterns generated by propagating actin waves11
SPOP is essential for DNA–protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex11
Chondroitin sulfate proteoglycan Windpipe modulates Hedgehog signaling inDrosophila11
p53 induces a survival transcriptional response after nucleolar stress11
Mitotic spindle: lessons from theoretical modeling11
Selective destabilization of polypeptides synthesized from NMD-targeted transcripts11
Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking11
Cross talk-dependent cortical patterning of Rho GTPases during cell repair11
Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole11
Regulation of apical constriction via microtubule- and Rab11-dependent apical transport during tissue invagination11
PICH regulates the abundance and localization of SUMOylated proteins on mitotic chromosomes11
Cell cycle oscillators underlying orderly proteolysis of E2F811
Powering morphogenesis: multiscale challenges at the interface of cell adhesion and the cytoskeleton11
Prostaglandins regulate invasive, collective border cell migration11
SCYL1 arginine methylation by PRMT1 is essential for neurite outgrowth via Golgi morphogenesis11
Spindle pole bodies function as signal amplifiers in the Mitotic Exit Network11
Dynein self-organizes while translocating the centrosome in T-cells11
Geometry of the nuclear envelope determines its flexural stiffness11
PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity11
Myosin II isoforms promote internalization of spatially distinct clathrin-independent endocytosis cargoes through modulation of cortical tension downstream of ROCK211
Membrane stretching activates calcium permeability of a putative channel Pkd2 during fission yeast cytokinesis10
The two-hit theory hits 5010
BORC-ARL8-HOPS ensemble is required for lysosomal cholesterol egress through NPC210
RAC1 induces nuclear alterations through the LINC complex to enhance melanoma invasiveness10
Phosphatidylinositol and phosphatidylinositol-3-phosphate activate HOPS to catalyze SNARE assembly, allowing small headgroup lipids to support the terminal steps of membrane fusion10
Integrin cross-talk modulates stiffness-independent motility of CD4+ T lymphocytes10
NgCAM and VAMP2 reveal that direct delivery and dendritic degradation maintain axonal polarity10
Coupling to substrate adhesions drives the maturation of muscle stress fibers into myofibrils within cardiomyocytes10
Spatial regulation of MCAK promotes cell polarization and focal adhesion turnover to drive robust cell migration10
A yeast FRET biosensor enlightens cAMP signaling10
Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets10
Resveratrol and related stilbene derivatives induce stress granules with distinct clearance kinetics10
Structural insights into the cause of human RSPH4A primary ciliary dyskinesia10
Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites10
More than just a ticket canceller: the mitochondrial processing peptidase tailors complex precursor proteins at internal cleavage sites10
Mapping the electrostatic profiles of cellular membranes10
Telomere length set point regulation in human pluripotent stem cells critically depends on the shelterin protein TPP110
Optical flow analysis reveals that Kinesin-mediated advection impacts the orientation of microtubules in theDrosophilaoocyte10
How good are my data? Reference standards in superresolution microscopy10
RUSC2 and WDR47 oppositely regulate kinesin–1-dependent distribution of ATG9A to the cell periphery10
Ase1 domains dynamically slow anaphase spindle elongation and recruit Bim1 to the midzone10
From stem cell to immune effector: how adhesion, migration, and polarity shape T-cell and natural killer cell lymphocyte development in vitro and in vivo10
Counting actin in contractile rings reveals novel contributions of cofilin and type II myosins to fission yeast cytokinesis10
ARHGAP4-SEPT2-SEPT9 complex enables both up- and down-modulation of integrin-mediated focal adhesions, cell migration, and invasion10
Rnd2 differentially regulates oligodendrocyte myelination at different developmental periods9
Genetically inspired in vitro reconstitution ofSaccharomyces cerevisiaeactin cables from seven purified proteins9
Doublecortin facilitates the elongation of the somatic Golgi apparatus into proximal dendrites9
Uveal melanoma cells use ameboid and mesenchymal mechanisms of cell motility crossing the endothelium9
Nucleoli and the nucleoli–centromere association are dynamic during normal development and in cancer9
Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity9
Roles for a lipid phosphatase in the activation of its opposing lipid kinase9
Maf1 regulates intracellular lipid homeostasis in response to DDR activation9
Polarized human cholangiocytes release distinct populations of apical and basolateral small extracellular vesicles9
Challenges and advice for MD/PhD applicants who are underrepresented in medicine9
Mechanosensitive mTORC2 independently coordinates leading and trailing edge polarity programs during neutrophil migration9
Heterophilic cell–cell adhesion of atypical cadherins Fat and Dachsous regulate epithelial cell size dynamics duringDrosophilathorax morphogenesis9
Co-regulation of the antagonistic RepoMan:Aurora-B pair in proliferating cells9
Scribble, Lgl1, and myosin II form a complex in vivo to promote directed cell migration9
Activation-induced substrate engagement in ERK signaling9
Fibronectin fibril alignment is established upon initiation of extracellular matrix assembly9
Contribution of increasing plasma membrane to the energetic cost of early zebrafish embryogenesis9
An update to the CRM1 cargo/NES database NESdb9
Modulating RhoA effectors induces transitions to oscillatory and more wavelike RhoA dynamics in Caenorhabditis elegans zygotes9
Docosahexanoic acid signals through the Nrf2–Nqo1 pathway to maintain redox balance and promote neurite outgrowth9
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein9
Myosin II and Arp2/3 cross-talk governs intracellular hydraulic pressure and lamellipodia formation8
Gαq-mediated calcium dynamics and membrane tension modulate neurite plasticity8
Alternate histories of cytokinesis: lessons from the trypanosomatids8
Spatial proximity of proteins surrounding zyxin under force-bearing conditions8
A novel mechanism for the retention of Golgi membrane proteins mediated by the Bre5p/Ubp3p deubiquitinase complex8
Nanoscale dynamics of actin filaments in the red blood cell membrane skeleton8
Scaling of biosynthesis and metabolism with cell size8
Functional characterization of MCAK/Kif2C cancer mutations using high-throughput microscopic analysis8
Survey of cancer cell anatomy in nonadhesive confinement reveals a role for filamin-A and fascin-1 in leader bleb–based migration8
Cell adaptation to aneuploidy by the environmental stress response dampens induction of the cytosolic unfolded-protein response8
Synergistic interactions between Cajal bodies and the miRNA processing machinery8
Cytoskeleton integrity influences XRCC1 and PCNA dynamics at DNA damage8
Septins and a formin have distinct functions in anaphase chiral cortical rotation in theCaenorhabditis eleganszygote8
Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms8
Hof1 plays a checkpoint-related role in MMS-induced DNA damage response in Candida albicans8
Nucleoporins’ exclusive amino acid sequence features regulate their transient interaction with and selectivity of cargo complexes in the nuclear pore8
Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility8
Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia8
The biochemical composition of the actomyosin network sets the magnitude of cellular traction forces8
One-step multiplex toolkit for efficient generation of conditional gene silencing human cell lines8
Costameric integrin and sarcoglycan protein levels are altered in aDrosophilamodel for Limb-girdle muscular dystrophy type 2H8
Centrosomes are required for proper β-catenin processing and Wnt response8
Myosin dilated cardiomyopathy mutation S532P disrupts actomyosin interactions, leading to altered muscle kinetics, reduced locomotion, and cardiac dilation in Drosophila8
Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport8
Quantitative live-cell PALM reveals nanoscopic Faa4 redistributions and dynamics on lipid droplets during metabolic transitions of yeast8
New signaling kid on the block: the role of the postmitotic midbody in polarity, stemness, and proliferation8
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to intraflagellar transport turnaround involving ICK/CILK18
Modeling a disease-correlated tubulin mutation in budding yeast reveals insight into MAP-mediated dynein function8
Cdc7-mediated phosphorylation of Cse4 regulates high-fidelity chromosome segregation in budding yeast8
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