Molecular Biology of the Cell

Papers
(The median citation count of Molecular Biology of the Cell is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Suppression of cofilin-1 promotes invasion in 3D hyaluronic acid matrices by promoting actin-based protrusions61
Nonmuscle myosin IIA (NMIIA) regulates anisotropic cell tension to maintain the hexagonal packing of mouse lens meridional row cells59
Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia47
Load adaptation by endocytic actin networks42
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic40
The outer kinetochore components KNL-1 and Ndc80 complex regulate axon and neuronal cell body positioning in the C. elegans nervous system38
Preprint Highlight: Multiplexed bioluminescence microscopy via phasor analysis35
Landmarks in the discovery of a role for actin in cell locomotion35
Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 233
Preprint Highlight: Mitotic clustering of pulverized chromosomes from micronuclei33
After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells33
Image-based discrimination of the early stages of mesenchymal stem cell differentiation32
Mitotic spindle membranes32
Mga2-mediated transcription supports mitotic nuclear expansion under lipid saturation conditions in stearoyl-CoA desaturase Ole1 mutant30
Dynamics of intracellular neonatal Fc receptor–ligand interactions in primary macrophages using biophysical fluorescence techniques29
Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence28
p97/VCP Promotes the Recycling of Endocytic Cargo26
Actin contraction controls nuclear blebbing and rupture independent of actin confinement25
STMND1 is a phylogenetically ancient stathmin which localizes to motile cilia and exhibits nuclear translocation that is inhibited when soluble tubulin concentration increases25
David Baltimore and the advent of eukaryotic RNA binding proteins25
Sec18 binds the tethering/SM complex HOPS to engage the Qc-SNARE for membrane fusion25
From pipette to palette: Bridging science and art at MBoC24
FHOD-1 and profilin protect sarcomeres against contraction-induced deformation> in C. elegans24
Preprint Highlight: Self‐supervised deep learning encodes high-resolution features of protein subcellular localization23
Heterologous expression of Dictyostelium discoideum NE81 in mouse embryo fibroblasts reveals conserved mechanoprotective roles of lamins23
Insights into the role of Nup62 and Nup93 in assembling cytoplasmic ring and central transport channel of the nuclear pore complex23
Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins22
A mathematical model of calcium signals around laser-induced epithelial wounds22
Osh-dependent and -independent Regulation of PI4P Levels During Polarized Growth ofSaccharomyces cerevisiae21
Preprint Highlight: Vimentin intermediate filaments organize organellar ER architecture in response to stress21
Preprint Highlight: Dynamic interplay of protrusive microtubule and contractile actomyosin forces drive tissue extension21
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding21
Calcium-binding Cab45 regulates the polarized apical secretion of soluble proteins in epithelial cells21
Preprint Highlight: Contractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis21
The nuclear isoforms of the Fragile X mental retardation RNA-binding protein associate with genomic DNA bridges20
Membrane lipids couple synaptotagmin to SNARE-mediated granule fusion in insulin-secreting cells20
A modified motor-clutch model reveals that neuronal growth cones respond faster to soft substrates20
The story of science: successes, failures, luck, privilege, and bias20
Delamination of epithelia induced by air–liquid interfaces20
HSPA8 inhibitors augment cancer chemotherapeutic effectiveness via potentiating necroptosis19
DAmFRET measures saturating concentrations and toxicities of protein phase transitions in vivo19
The initiation and early development of the tubulin-containing cytoskeleton in the human parasite Toxoplasma gondii19
LYSET facilitates integration of both the N- and C-terminal transmembrane helices/cytoplasmic domains of GlcNAc-1-phosphotransferase19
Big1 is a newly identified autophagy regulator that is critical for a fully functional V-ATPase19
Nir1 constitutively localizes at ER–PM junctions and promotes Nir2 recruitment for PIP2 homeostasis18
EHD2 regulates plasma membrane integrity and downstream insulin receptor signaling events18
Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility18
Cell Painting predicts impact of lung cancer variants18
New signaling kid on the block: the role of the postmitotic midbody in polarity, stemness, and proliferation18
Cell type- and transcription-independent spatial proximity between enhancers and promoters17
The SNARE-associated protein Sft2 functions in Imh1-mediated SNARE recycling transport upon ER stress17
Cytoplasmic preassembly of the flagellar outer dynein arm complex in Trypanosoma brucei17
Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D317
LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis17
Spatiotemporal analysis of F-actin polymerization with micropillar arrays reveals synchronization between adhesion sites17
Scaling of biosynthesis and metabolism with cell size17
Preexisting tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia17
Regulation of misfolded protein aggregation and degradation by SUMOylation in budding yeast17
The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential17
The Kinesin-14 tail: Dual microtubule binding domains drive spindle morphogenesis through tight microtubule cross-linking and robust sliding17
Cell segregation via differential collision modes between heterotypic cell populations17
Regulation of membrane scission in yeast endocytosis17
Orchestrating nonmuscle myosin II filament assembly at the onset of cytokinesis17
Intracellular diffusion in the cytoplasm increases with cell size in fission yeast17
Mechanisms underlying Myosin 10′s contribution to the maintenance of mitotic spindle bipolarity16
Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport16
Practical guide to fluorescence lifetime imaging microscopy16
Nucleoli in epithelial cell collectives respond to tumorigenic, spatial, and mechanical cues16
Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells16
Lgd regulates ESCRT-III complex accumulation at multivesicular endosomes to control intralumenal vesicle formation16
MotiQ: an open-source toolbox to quantify the cell motility and morphology of microglia15
Visualization of the three-dimensional structure of the human centromere in mitotic chromosomes by superresolution microscopy15
Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division15
The Rab11-family interacting proteins reveal selective interaction of mammalian recycling endosomes with theToxoplasmaparasitophorous vacuole in a Rab11- and Arf6-dependent manner15
The biophysical mechanism of mitochondrial pearling15
Serotonin 5-HT7 receptor slows down the Gs protein: a single molecule perspective15
Ehg1/May24 stabilizes yeast amino acid permease by facilitating its localization to lipid rafts under high hydrostatic pressure15
Atypical and distinct microtubule radial symmetries in the centriole and the axoneme of Lecudina tuzetae15
Plectin linkages are mechanosensitive and required for the nuclear piston mechanism of three-dimensional cell migration15
Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization14
Preprint Highlight: Real-time denoising of fluorescence time-lapse imaging enables high-sensitivity observations of biological dynamics beyond the shot-noise limit14
The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration14
Interaction of the sorting nexin 25 homologue Snazarus with Rab11 balances endocytic and secretory transport and maintains the ultrafiltration diaphragm in nephrocytes14
Distinct peroxisome populations differentially respond to alcohol-associated hepatic injury14
Breaking the rules of cell biology: Lessons from the liver's exceptional regenerative capacity14
Remodeling of cytoskeleton, chromatin, and gene expression during mechanical rejuvenation of aged human dermal fibroblasts14
Combining multiple fluorescence imaging techniques in biology: when one microscope is not enough14
Outer-arm dynein light chain LC1 is required for normal motor assembly kinetics, ciliary stability, and motility14
p115RhoGEF activates RhoA to support tight junction maintenance and remodeling14
Modification of the neck-linker of KIF18A alters Microtubule subpopulation preference14
DLC-1 facilitates germ granule assembly in Caenorhabditis elegans embryo13
Drosophila Fog/Cta and T48 pathways have overlapping and distinct contributions to mesoderm invagination13
Innate Immune Crosstalk: The Central Role of Neutrophils and Macrophages in ANCA-Associated Vasculitis13
Activation of the ChvG–ChvI pathway promotes survival during cell wall stress in Agrobacterium tumefaciens13
An updated SYSCILIA gold standard (SCGSv2) of known ciliary genes, revealing the vast progress that has been made in the cilia research field13
A multiparametric activity profiling platform for neuron disease phenotyping and drug screening13
Temporal control of contact site formation reveals a relationship between mitochondrial division and Num1-mediated mitochondrial tethering13
Endothelial tip/stalk cell selection requires BMP9-induced βIV-spectrin expression during sprouting angiogenesis13
Loss of CHMP2A implicates an ordered assembly of ESCRT-III proteins during cytokinetic abscission13
FOXO nuclear shuttling dynamics are stimulus-dependent and correspond with cell fate13
Tools for live-cell imaging of cytoskeletal and nuclear behavior in the unconventional yeast, Aureobasidium pullulans13
A role for the kinetochore protein, NUF2, in ribosome biogenesis13
Hsp40s play distinct roles during the initial stages of apolipoprotein B biogenesis13
Neuronal membrane proteasome-derived peptides modulate NMDAR-dependent neuronal signaling to promote changes in gene expression13
Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis13
Phospholipase D1 produces phosphatidic acid at sites of secretory vesicle docking and fusion13
Multiple tethers of organelle contact sites are involved in α-synuclein toxicity in yeast13
2022 ASCB Annual Meeting abstracts13
Antiparallel microtubule bundling supports KIF15-driven mitotic spindle assembly12
The role of neurofilament transport in the radial growth of myelinated axons12
Independence of centromeric and pericentromeric chromatin stability on CCAN components12
WAVE facilitates polarized E-cadherin transport12
Transient PP2A SIP complex localization to mitotic SPBs for SIN inhibition is mediated solely by the Csc1 FHA domain12
Quantitative analysis of morphogenesis and growth dynamics in an obligate intracellular bacterium12
Septin organization is regulated by the Gpa1 ubiquitination domain and endocytic machinery during the yeast pheromone response12
The transcriptional response to oxidative stress is independent of stress-granule formation12
Loss of intermicrovillar adhesion factor CDHR2 impairs basolateral junctional complexes in transporting epithelia12
Complex state transitions of the bacterial cell division protein FtsZ12
The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation12
Loss of negative regulation by HDAC1 and REST contributes to MAD1 overexpression in breast cancer12
RAD51 regulates eukaryotic chromatin motions in the absence of DNA damage12
Imaging-based screen identifies novel natural compounds that perturb cell and chloroplast division in Chlamydomonas reinhardtii12
Nucleolar structure connects with global nuclear organization12
Ovarian carcinoma immunoreactive antigen–like protein 2 (OCIAD2) is a novel complex III–specific assembly factor in mitochondria12
Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells12
Preprint Highlight: The novel Rab5 effector FERRY links early endosomes with the translation machinery12
Nkd1 functions downstream of Axin2 to attenuate Wnt signaling12
A WICB 50th Favorite: Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment11
Growth cone macropinocytosis of neurotrophin receptor and neuritogenesis are regulated by neuron navigator 111
Preprint Highlight: Deciphering the tumor-specific immunopeptidome in vivo with genetically engineered mouse models11
The RhoGAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle11
The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells11
The TOG5 domain of CKAP5 is required to interact with F-actin and promote microtubule advancement in neurons11
Identification of a Golgi-localized peptide reveals a minimal Golgi-targeting motif11
A novel tool for the unbiased characterization of epithelial monolayer development in culture11
Preprint Highlight: Probing the rules of cell coordination in live tissues by interpretable machine learning based on graph neural networks11
Preprint Highlight: FLAgellum Member 8 modulates extravascular trypanosome distribution in the mammalian host11
Polymer dynamics of Alp7A reveals how two critical concentrations govern assembly of dynamically unstable actin-like proteins11
Dynein-dependent collection of membranes defines the architecture and position of microtubule asters in isolated, geometrically confined volumes of cell-free extracts11
Recruitment of PI4KIIIβ to the Golgi by ACBD3 is dependent on an upstream pathway of a SNARE complex and golgins11
Systematic analysis of microtubule plus-end networks defines EB-cargo complexes critical for mitosis in budding yeast11
Recruitment of the lipid kinase Mss4 to the meiotic spindle pole promotes prospore membrane formation in Saccharomyces cerevisiae11
The Drosophila spectraplakin Short stop regulates focal adhesion dynamics by cross-linking microtubules and actin11
Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole11
Role of Gα–MAPK interaction in mating of Saccharomyces cerevisiae11
WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration11
Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei10
Preprint Highlight: LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia via Transcription Factor E3 Inhibition10
Nanotopography modulates cytoskeletal organization and dynamics during T cell activation10
Polymer models reveal how chromatin modification can modulate force at the kinetochore10
K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif1510
How many authors does it take to publish a high profile or classic paper?10
CANVS: an easy-to-use application for the analysis and visualization of mass spectrometry–based protein–protein interaction/association data10
2021 ASCB Annual Meeting abstracts10
CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis10
Results from the MBoC Preprint Highlight experiment10
Fission yeast Pdk1 kinase regulates cytokinesis and eisosomes10
The roles of yeast formins and their regulators Bud6 and Bil2 in the pheromone response10
A role for Nup153 in nuclear assembly reveals differential requirements for targeting of nuclear envelope constituents10
Mutation of the PEBP-like domain of the mitoribosomal MrpL35/mL38 protein results in production of nascent chains with impaired capacity to assemble into OXPHOS complexes10
In vivo imaging reveals independent intraflagellar transport of the nexin–dynein regulatory complex subunits DRC2 and DRC410
Preprint Highlight: PGC1α regulates the endothelial response to fluid shear stress via telomerase reverse transcriptase control of heme oxygenase‐110
Plasma membrane protrusions mediate host cell–cell fusion induced by Burkholderia thailandensis10
Scaling of nuclear numbers and their spatial arrangement in skeletal muscle cell size regulation10
Automated segmentation of soft X-ray tomography: Native cellular structure with submicron resolution at high-throughput for whole-cell quantitative imaging in yeast10
Three types of actomyosin rings within a common cytoplasm exhibit distinct modes of contractility9
Correction for Article Title “The laforin-malin complex, involved in Lafora disease, promotes the incorporation of K63-linked ubiquitin chains into AMP-activated protein kinase beta subunits”.9
Dishevelled controls bulk cadherin dynamics and the stability of individual cadherin clusters during convergent extension9
Preprint Highlight: Detyrosination enrichment on microtubule subsets is established by the interplay between a stochastically acting enzyme and microtubule stability9
Membrane fusion by Drosophila atlastin does not require GTP hydrolysis9
Ultrastructure of COPII vesicle formation in yeast characterized by correlative light and electron microscopy9
VAC14 oligomerization is essential for the function of the FAB1/PIKfyve–VAC14–FIG4 complex9
Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids9
Diffusion within the synaptonemal complex can account for signal transduction along meiotic chromosomes9
A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly9
Deafness mutation in the MYO3A motor domain impairs actin protrusion elongation mechanism9
Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates9
Powering morphogenesis: multiscale challenges at the interface of cell adhesion and the cytoskeleton9
Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes9
Superresolution microscopy reveals actomyosin dynamics in medioapical arrays9
VAMP5 promotes Fcγ receptor-mediated phagocytosis and regulates phagosome maturation in macrophages9
FAZ assembly in bloodstream formTrypanosoma bruceirequires kinesin KIN-E9
Large-scale mapping of positional changes of hypoxia-responsive genes upon activation9
Strained Actin Binding by the Prickle2 LIM Domains and their Regulation in the Full-Length Protein9
The lipid droplet protein Jabba promotes actin remodeling downstream of prostaglandin signaling during Drosophila oogenesis9
The two-hit theory hits 509
A dedicated cytoplasmic container collects extrachromosomal DNA away from the mammalian nucleus9
L-bodies are RNA–protein condensates driving RNA localization in Xenopus oocytes9
Maximizing Access to Cell Biology for PEERS: Retracting the term minority in favor of a more inclusive lexicon9
Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants9
FAP20 is required for flagellum assembly in Trypanosoma brucei9
AP-4 regulates neuronal lysosome composition, function, and transport via regulating export of critical lysosome receptor proteins at the trans-Golgi network9
A methodology for specific disruption of microtubule polymerization into dendritic spines9
Preprint Highlight: Actomyosin cables position cell cohorts during Drosophila germband retraction by entraining their morphodynamic and mechanical properties9
Preprint Highlight: Transcriptomic changes highly similar to Alzheimer's disease are observed in a subpopulation of individuals during normal brain aging9
Traveling-wave chemotaxis of neutrophil-like HL-60 cells9
Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants9
Basal autophagy during meiotic prophase I is required for accurate chromosome segregation in Drosophila oocytes and declines during oocyte aging9
Did axons evolve by activating cytokinesis during interphase? A hypothesis on the origin of neurons9
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation9
Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization9
Cilia.Pro database of ciliary proteins from vertebrates, Chlamydomonas, and Caenorhabditis9
Trafficking of K63-polyubiquitin–modified membrane proteins in a macroautophagy-independent pathway is linked to ATG9A9
MRE11-independent effects of Mirin on mitochondrial DNA integrity and cellular immune responses8
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations8
The unfolded protein response of the endoplasmic reticulum supports mitochondrial biogenesis by buffering nonimported proteins8
The C-terminus of α-Synuclein Regulates its Dynamic Cellular Internalization by Neurexin 1β8
Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif8
Regulation of p65 nuclear localization and chromatin states by compressive force8
Inhibition of the chromatin remodeling factor NURF rescued sterility by a clinic variant of NuRD8
Preprint Highlight: Learning orientation-invariant representations enables accurate and robust morphologic profiling of cells and organelles8
Michael Patrick Sheetz, 1946–2025, a devotee of and major contributor to membrane and cytoskeletal biology8
Inositol 1, 4, 5-trisphosphate receptor is required for spindle assembly in Xenopus oocytes8
Isoform-specific phosphorylation of axonemal dynein heavy chains8
The DEAD-box RNA helicase DDX28 suppresses cell migration and 3D growth and invasion in MDA-MB-231 cells by altering bioenergetics8
The [PSI+] prion modulates cytochrome c oxidase deficiency caused by deletion of COX128
Retraction8
Myosin F controls actin organization and dynamics in Toxoplasma gondii8
A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase8
Homology-directed repair involves multiple strand invasion cycles in fission yeast8
Functional fluorescence labeling of actins in live-cell system using engineered split-GFP technology8
Enabled primarily controls filopodial morphology, not actin organization, in the TSM1 growth cone inDrosophila8
Dysregulation of ceramide metabolism causes phytoceramide-dependent induction of the unfolded protein response8
M phase–specific generation of supernumerary centrioles in cancer cells8
Membrane stretching activates calcium permeability of a putative channel Pkd2 during fission yeast cytokinesis8
Med13 is required for efficient P-body recruitment and autophagic degradation of Edc3 following nitrogen starvation8
The myosin chaperone UNC-45 has an important role in maintaining the structure and function of muscle sarcomeres during adult aging8
VAMP2 and synaptotagmin mobility in chromaffin granule membranes: implications for regulated exocytosis8
SPAK-dependent cotransporter activity mediates capillary adhesion and pressure during glioblastoma migration in confined spaces8
Parkinson disease–associated toxic exposures selectively up-regulate vesicular glutamate transporter vGlut2 in a model of human cortical neurons8
Evidence for novel mechanisms that control cell-cycle entry and cell size8
Quantification of microtubule stutters: dynamic instability behaviors that are strongly associated with catastrophe8
The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes8
Endosome maturation during ER stress relies on the ubiquitin-binding domain of histone deacetylase 68
Differentiation-dependent changes in lamin B1 dynamics and lamin B receptor localization8
Preprint Highlight: The mechanosensitive ion channel Piezo mediates Rho activation and actin stress fibre formation in Drosophila nephrocytes8
Preprint Highlight: Disruption of lactate metabolism in the peripheral nervous system leads to motor selective deficits8
A PACAP-activated network for secretion requires coordination of Ca2+ influx and Ca2+ mobilization8
Ras-mediated activation of mTORC2 promotes breast epithelial cell migration and invasion8
SEL1L regulates ER homeostasis in Sertoli cells but is dispensable for their function8
MARVEL domain containing CMTM4 affects CXCR4 trafficking8
Protein phosphatase 2A (PP2A) promotes anaphase entry after DNA replication stress in budding yeast7
Hedgehog-induced ciliary trafficking of kinesin-4 motor KIF7 requires intraflagellar transport but not KIF7’s microtubule binding7
Mitochondrial dysfunction and lipid dysregulation in yeast lacking phosphatidylserine7
Preprint Highlight: Intertissue mechanical interactions shape the olfactory circuit in zebrafish7
Preprint Highlight: Cell adhesions link subcellular actomyosin dynamics to tissue-scale-force production during vertebrate convergent extension7
F-actin organization and target constriction during primary macrophage phagocytosis is balanced by competing activity of myosin-I and myosin-II7
Lateral and longitudinal compaction of PRC1 overlap zones drives stabilization of interzonal microtubules7
Computational simulations reveal that Abl activity controls cohesiveness of actin networks in growth cones7
FARL-11 (STRIP1/2) is required for sarcomere and sarcoplasmic reticulum organization in C. elegans7
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