Molecular Biology of the Cell

Article	Citations
David Baltimore and the advent of eukaryotic RNA binding proteins	65
STMND1 is a phylogenetically ancient stathmin which localizes to motile cilia and exhibits nuclear translocation that is inhibited when soluble tubulin concentration increases	51
Suppression of cofilin-1 promotes invasion in 3D hyaluronic acid matrices by promoting actin-based protrusions	46
Nonmuscle myosin IIA (NMIIA) regulates anisotropic cell tension to maintain the hexagonal packing of mouse lens meridional row cells	41
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic	38
Preprint Highlight: Multiplexed bioluminescence microscopy via phasor analysis	36
The outer kinetochore components KNL-1 and Ndc80 complex regulate axon and neuronal cell body positioning in the C. elegans nervous system	36
Preprint Highlight: Mitotic clustering of pulverized chromosomes from micronuclei	35
Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2	32
Mga2-mediated transcription supports mitotic nuclear expansion under lipid saturation conditions in stearoyl-CoA desaturase Ole1 mutant	29
Dynamics of intracellular neonatal Fc receptor–ligand interactions in primary macrophages using biophysical fluorescence techniques	27
Load adaptation by endocytic actin networks	26
Landmarks in the discovery of a role for actin in cell locomotion	26
Mitotic spindle membranes	26
Systematic evaluation of tools for auxin-inducible protein degradation in budding yeast	25
Actin contraction controls nuclear blebbing and rupture independent of actin confinement	25
Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence	24
Hydrostatic pressure from basal side promotes cancer proliferation, enhances migration, and alters cell polarity: A model of the effects of interstitial fluid pressure in tumor microenvironment	24
After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells	24
Image-based discrimination of the early stages of mesenchymal stem cell differentiation	23
p97/VCP Promotes the Recycling of Endocytic Cargo	23
FHOD-1 and profilin protect sarcomeres against contraction-induced deformation> in C. elegans	22
Sec18 binds the tethering/SM complex HOPS to engage the Qc-SNARE for membrane fusion	22
From pipette to palette: Bridging science and art at MBoC	22
Preprint Highlight: Self‐supervised deep learning encodes high-resolution features of protein subcellular localization	22

Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia	22
Preprint Highlight: Dynamic interplay of protrusive microtubule and contractile actomyosin forces drive tissue extension	21
Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility	21
Preprint Highlight: Vimentin intermediate filaments organize organellar ER architecture in response to stress	21
Preprint Highlight: Contractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis	21
Osh-dependent and -independent Regulation of PI4P Levels During Polarized Growth ofSaccharomyces cerevisiae	21
HSPA8 inhibitors augment cancer chemotherapeutic effectiveness via potentiating necroptosis	20
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding	20
A modified motor-clutch model reveals that neuronal growth cones respond faster to soft substrates	20
Big1 is a newly identified autophagy regulator that is critical for a fully functional V-ATPase	19
Membrane lipids couple synaptotagmin to SNARE-mediated granule fusion in insulin-secreting cells	19
A mathematical model of calcium signals around laser-induced epithelial wounds	19
LYSET facilitates integration of both the N- and C-terminal transmembrane helices/cytoplasmic domains of GlcNAc-1-phosphotransferase	19
Calcium-binding Cab45 regulates the polarized apical secretion of soluble proteins in epithelial cells	19
Insights into the role of Nup62 and Nup93 in assembling cytoplasmic ring and central transport channel of the nuclear pore complex	19
EHD2 regulates plasma membrane integrity and downstream insulin receptor signaling events	19
The nuclear isoforms of the Fragile X mental retardation RNA-binding protein associate with genomic DNA bridges	19
Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins	19
New signaling kid on the block: the role of the postmitotic midbody in polarity, stemness, and proliferation	18
Cell Painting predicts impact of lung cancer variants	18
Scaling of biosynthesis and metabolism with cell size	18
Delamination of epithelia induced by air–liquid interfaces	18
Cell type- and transcription-independent spatial proximity between enhancers and promoters	18
DAmFRET measures saturating concentrations and toxicities of protein phase transitions in vivo	18
Nir1 constitutively localizes at ER–PM junctions and promotes Nir2 recruitment for PIP2 homeostasis	18
The initiation and early development of the tubulin-containing cytoskeleton in the human parasite Toxoplasma gondii	18
The SNARE-associated protein Sft2 functions in Imh1-mediated SNARE recycling transport upon ER stress	17
LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis	17
Mechanisms underlying Myosin 10′s contribution to the maintenance of mitotic spindle bipolarity	17
Cytoplasmic preassembly of the flagellar outer dynein arm complex in Trypanosoma brucei	17
Practical guide to fluorescence lifetime imaging microscopy	17
Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport	17
Orchestrating nonmuscle myosin II filament assembly at the onset of cytokinesis	17
Heterologous expression of Dictyostelium discoideum NE81 in mouse embryo fibroblasts reveals conserved mechanoprotective roles of lamins	17
Plectin linkages are mechanosensitive and required for the nuclear piston mechanism of three-dimensional cell migration	17
A system for high-throughput axonal imaging of induced pluripotent stem cell-derived human i 3 Neurons	17
Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells	16
Cell segregation via differential collision modes between heterotypic cell populations	16
MotiQ: an open-source toolbox to quantify the cell motility and morphology of microglia	16
Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division	16
Lgd regulates ESCRT-III complex accumulation at multivesicular endosomes to control intralumenal vesicle formation	16
Atypical and distinct microtubule radial symmetries in the centriole and the axoneme of Lecudina tuzetae	16
The Rab11-family interacting proteins reveal selective interaction of mammalian recycling endosomes with the Toxoplasma parasitophorous vacuole in a Rab1	16
The biophysical mechanism of mitochondrial pearling	16
Serotonin 5-HT7 receptor slows down the Gs protein: a single molecule perspective	16
Regulation of membrane scission in yeast endocytosis	15
Nucleoli in epithelial cell collectives respond to tumorigenic, spatial, and mechanical cues	15
Intracellular diffusion in the cytoplasm increases with cell size in fission yeast	15
Regulation of misfolded protein aggregation and degradation by SUMOylation in budding yeast	15
Preexisting tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia	15

Spatiotemporal analysis of F-actin polymerization with micropillar arrays reveals synchronization between adhesion sites	15
Ehg1/May24 stabilizes yeast amino acid permease by facilitating its localization to lipid rafts under high hydrostatic pressure	15
The Kinesin-14 tail: Dual microtubule binding domains drive spindle morphogenesis through tight microtubule cross-linking and robust sliding	15
Visualization of the three-dimensional structure of the human centromere in mitotic chromosomes by superresolution microscopy	15
The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential	15
Distinct peroxisome populations differentially respond to alcohol-associated hepatic injury	15
Tools for live-cell imaging of cytoskeletal and nuclear behavior in the unconventional yeast, Aureobasidium pullulans	14
Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization	14
Preprint Highlight: Real-time denoising of fluorescence time-lapse imaging enables high-sensitivity observations of biological dynamics beyond the shot-noise limit	14
p115RhoGEF activates RhoA to support tight junction maintenance and remodeling	14
The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration	14
Activation of the ChvG–ChvI pathway promotes survival during cell wall stress in Agrobacterium tumefaciens	14
Interaction of the sorting nexin 25 homologue Snazarus with Rab11 balances endocytic and secretory transport and maintains the ultrafiltration diaphragm in nephrocytes	14
Modification of the neck-linker of KIF18A alters Microtubule subpopulation preference	14
Outer-arm dynein light chain LC1 is required for normal motor assembly kinetics, ciliary stability, and motility	14
FOXO nuclear shuttling dynamics are stimulus-dependent and correspond with cell fate	13
Remodeling of cytoskeleton, chromatin, and gene expression during mechanical rejuvenation of aged human dermal fibroblasts	13
Phospholipase D1 produces phosphatidic acid at sites of secretory vesicle docking and fusion	13
Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis	13
Septin organization is regulated by the Gpa1 ubiquitination domain and endocytic machinery during the yeast pheromone response	13
Actin and vimentin jointly control cell viscoelasticity and compression stiffening	13
Combining multiple fluorescence imaging techniques in biology: when one microscope is not enough	13
DLC-1 facilitates germ granule assembly in Caenorhabditis elegans embryo	13
Loss of CHMP2A implicates an ordered assembly of ESCRT-III proteins during cytokinetic abscission	13
Temporal control of contact site formation reveals a relationship between mitochondrial division and Num1-mediated mitochondrial tethering	13
Breaking the rules of cell biology: Lessons from the liver's exceptional regenerative capacity	13
Multiple tethers of organelle contact sites are involved in α-synuclein toxicity in yeast	13
Drosophila Fog/Cta and T48 pathways have overlapping and distinct contributions to mesoderm invagination	13
Neuronal membrane proteasome-derived peptides modulate NMDAR-dependent neuronal signaling to promote changes in gene expression	13
The mammalian class IX myosins Myo9a and Myo9b use different cellular actin assemblies for force production and regulation of Rho activity	13
2022 ASCB Annual Meeting abstracts	13
Endothelial tip/stalk cell selection requires BMP9-induced βIV-spectrin expression during sprouting angiogenesis	12
A multiparametric activity profiling platform for neuron disease phenotyping and drug screening	12
A role for the kinetochore protein, NUF2, in ribosome biogenesis	12
Celebrating Women in Academia and Addressing Underrepresentation	12
Loss of negative regulation by HDAC1 and REST contributes to MAD1 overexpression in breast cancer	12
Preprint Highlight: FLAgellum Member 8 modulates extravascular trypanosome distribution in the mammalian host	12
Role of Gα–MAPK interaction in mating of Saccharomyces cerevisiae	12
RAD51 regulates eukaryotic chromatin motions in the absence of DNA damage	12
Imaging-based screen identifies novel natural compounds that perturb cell and chloroplast division in Chlamydomonas reinhardtii	12
Innate immune cross-talk: The central role of neutrophils and macrophages in ANCA-associated vasculitis	12
The transcriptional response to oxidative stress is independent of stress-granule formation	12
Loss of intermicrovillar adhesion factor CDHR2 impairs basolateral junctional complexes in transporting epithelia	12
Dynein-dependent collection of membranes defines the architecture and position of microtubule asters in isolated, geometrically confined volumes of cell-free extracts	12
The RhoGAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle	12
Preprint Highlight: The novel Rab5 effector FERRY links early endosomes with the translation machinery	12
Preprint Highlight: Deciphering the tumor-specific immunopeptidome in vivo with genetically engineered mouse models	12
Hsp40s play distinct roles during the initial stages of apolipoprotein B biogenesis	12
Ovarian carcinoma immunoreactive antigen–like protein 2 (OCIAD2) is a novel complex III–specific assembly factor in mitochondria	12
Antiparallel microtubule bundling supports KIF15-driven mitotic spindle assembly	12
Complex state transitions of the bacterial cell division protein FtsZ	12
The role of neurofilament transport in the radial growth of myelinated axons	12
Recruitment of the lipid kinase Mss4 to the meiotic spindle pole promotes prospore membrane formation in Saccharomyces cerevisiae	12
Preprint Highlight: Probing the rules of cell coordination in live tissues by interpretable machine learning based on graph neural networks	12
Transient PP2A SIP complex localization to mitotic SPBs for SIN inhibition is mediated solely by the Csc1 FHA domain	12
Mutation of the PEBP-like domain of the mitoribosomal MrpL35/mL38 protein results in production of nascent chains with impaired capacity to assemble into OXPHOS complexes	11
Strained actin binding by the Prickle2 LIM domains and their regulation in the full-length protein	11
Growth cone macropinocytosis of neurotrophin receptor and neuritogenesis are regulated by neuron navigator 1	11
Polymer dynamics of Alp7A reveals how two critical concentrations govern assembly of dynamically unstable actin-like proteins	11
WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration	11
Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells	11
Nanotopography modulates cytoskeletal organization and dynamics during T cell activation	11
WAVE facilitates polarized E-cadherin transport	11
The Drosophila spectraplakin Short stop regulates focal adhesion dynamics by cross-linking microtubules and actin	11
Quantitative analysis of morphogenesis and growth dynamics in an obligate intracellular bacterium	11
The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation	11
Nkd1 functions downstream of Axin2 to attenuate Wnt signaling	11
Identification of a Golgi-localized peptide reveals a minimal Golgi-targeting motif	11
The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells†	11
Independence of centromeric and pericentromeric chromatin stability on CCAN components	11
The TOG5 domain of CKAP5 is required to interact with F-actin and promote microtubule advancement in neurons	11
Nucleolar structure connects with global nuclear organization	11
Results from the MBoC Preprint Highlight experiment	10
A WICB 50th Favorite: Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment	10
Plasma membrane protrusions mediate host cell–cell fusion induced by Burkholderia thailandensis	10
Maximizing Access to Cell Biology for PEERS: Retracting the term minority in favor of a more inclusive lexicon	10
Membrane fusion by Drosophila atlastin does not require GTP hydrolysis	10
Recruitment of PI4KIIIβ to the Golgi by ACBD3 is dependent on an upstream pathway of a SNARE complex and golgins	10
Large-scale mapping of positional changes of hypoxia-responsive genes upon activation	10
Polymer models reveal how chromatin modification can modulate force at the kinetochore	10

A role for Nup153 in nuclear assembly reveals differential requirements for targeting of nuclear envelope constituents	10
Preprint Highlight: PGC1α regulates the endothelial response to fluid shear stress via telomerase reverse transcriptase control of heme oxygenase‐1	10
Scaling of nuclear numbers and their spatial arrangement in skeletal muscle cell size regulation	10
Preprint Highlight: Transcriptomic changes highly similar to Alzheimer's disease are observed in a subpopulation of individuals during normal brain aging	10
Preprint Highlight: Actomyosin cables position cell cohorts during Drosophila germband retraction by entraining their morphodynamic and mechanical properties	10
Did axons evolve by activating cytokinesis during interphase? A hypothesis on the origin of neurons	10
A new subset of mitochondrial-derived vesicles perform inter-mitochondrial communications	10
Systematic analysis of microtubule plus-end networks defines EB-cargo complexes critical for mitosis in budding yeast	10
Automated segmentation of soft X-ray tomography: Native cellular structure with submicron resolution at high-throughput for whole-cell quantitative imaging in yeast	10
The roles of yeast formins and their regulators Bud6 and Bil2 in the pheromone response	10
Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei	10
Preprint Highlight: LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia via Transcription Factor E3 Inhibition	10
CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis	10
A novel tool for the unbiased characterization of epithelial monolayer development in culture	10
A methodology for specific disruption of microtubule polymerization into dendritic spines	10
Preprint Highlight: Detyrosination enrichment on microtubule subsets is established by the interplay between a stochastically acting enzyme and microtubule stability	10
How many authors does it take to publish a high profile or classic paper?	10
In vivo imaging reveals independent intraflagellar transport of the nexin–dynein regulatory complex subunits DRC2 and DRC4	10
Fission yeast Pdk1 kinase regulates cytokinesis and eisosomes	10
Dysregulation of ceramide metabolism causes phytoceramide-dependent induction of the unfolded protein response	9
Homology-directed repair involves multiple strand invasion cycles in fission yeast	9
Enabled primarily controls filopodial morphology, not actin organization, in the TSM1 growth cone inDrosophila	9
Preprint Highlight: Learning orientation-invariant representations enables accurate and robust morphologic profiling of cells and organelles	9
Superresolution microscopy reveals actomyosin dynamics in medioapical arrays	9
Michael Patrick Sheetz, 1946–2025, a devotee of and major contributor to membrane and cytoskeletal biology	9
Traveling-wave chemotaxis of neutrophil-like HL-60 cells	9
Dishevelled controls bulk cadherin dynamics and the stability of individual cadherin clusters during convergent extension	9
A dedicated cytoplasmic container collects extrachromosomal DNA away from the mammalian nucleus	9
Preprint Highlight: The mechanosensitive ion channel Piezo mediates Rho activation and actin stress fibre formation in Drosophila nephrocytes	9
VAMP5 promotes Fcγ receptor-mediated phagocytosis and regulates phagosome maturation in macrophages	9
Deafness mutation in the MYO3A motor domain impairs actin protrusion elongation mechanism	9
Basal autophagy during meiotic prophase I is required for accurate chromosome segregation in Drosophila oocytes and declines during oocyte aging	9
Evidence for novel mechanisms that control cell-cycle entry and cell size	9
Three types of actomyosin rings within a common cytoplasm exhibit distinct modes of contractility	9
Inhibition of the chromatin remodeling factor NURF rescued sterility by a clinic variant of NuRD	9
M phase–specific generation of supernumerary centrioles in cancer cells	9
VAC14 oligomerization is essential for the function of the FAB1/PIKfyve–VAC14–FIG4 complex	9
FAP20 is required for flagellum assembly in Trypanosoma brucei	9
FAZ assembly in bloodstream form Trypanosoma brucei requires kinesin KIN-E	9
Trafficking of K63-polyubiquitin–modified membrane proteins in a macroautophagy-independent pathway is linked to ATG9A	9
Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids	9
A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly	9
Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates	9
Membrane stretching activates calcium permeability of a putative channel Pkd2 during fission yeast cytokinesis	9
Ultrastructure of COPII vesicle formation in yeast characterized by correlative light and electron microscopy	9
A PACAP-activated network for secretion requires coordination of Ca 2+ influx and Ca 2+ mobilizati	9
The unfolded protein response of the endoplasmic reticulum supports mitochondrial biogenesis by buffering nonimported proteins	9
The lipid droplet protein Jabba promotes actin remodeling downstream of prostaglandin signaling during Drosophila oogenesis	9
Preprint Highlight: Disruption of lactate metabolism in the peripheral nervous system leads to motor selective deficits	9
Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes	9
Powering morphogenesis: multiscale challenges at the interface of cell adhesion and the cytoskeleton	9
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation	9
Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants	9
Correction for Article Title “The laforin-malin complex, involved in Lafora disease, promotes the incorporation of K63-linked ubiquitin chains into AMP-activated protein kinase beta subunits”.	9
Cilia.Pro database of ciliary proteins from vertebrates, Chlamydomonas , and Caenorhabditis	9
Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization	9
Diffusion within the synaptonemal complex can account for signal transduction along meiotic chromosomes	9
SPAK-dependent cotransporter activity mediates capillary adhesion and pressure during glioblastoma migration in confined spaces	8
MARVEL domain containing CMTM4 affects CXCR4 trafficking	8
Mechanical strategies supporting growth and size diversity in Filamentous Fungi	8
The [PSI+] prion modulates cytochrome c oxidase deficiency caused by deletion of COX12	8
Med13 is required for efficient P-body recruitment and autophagic degradation of Edc3 following nitrogen starvation	8
Differentiation-dependent changes in lamin B1 dynamics and lamin B receptor localization	8
Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif	8
Regulation of p65 nuclear localization and chromatin states by compressive force	8
MRE11-independent effects of Mirin on mitochondrial DNA integrity and cellular immune responses	8
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations	8
VAMP2 and synaptotagmin mobility in chromaffin granule membranes: implications for regulated exocytosis	8
The DEAD-box RNA helicase DDX28 suppresses cell migration and 3D growth and invasion in MDA-MB-231 cells by altering bioenergetics	8
Isoform-specific phosphorylation of axonemal dynein heavy chains	8
Endosome maturation during ER stress relies on the ubiquitin-binding domain of histone deacetylase 6	8
The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes	8
Parkinson disease–associated toxic exposures selectively up-regulate vesicular glutamate transporter vGlut2 in a model of human cortical neurons	8
Quantification of microtubule stutters: dynamic instability behaviors that are strongly associated with catastrophe	8
A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase	8
Remarkable chromosomes and karyotypes: A top 10 list	8
Retraction	8
The myosin chaperone UNC-45 has an important role in maintaining the structure and function of muscle sarcomeres during adult aging	8
Myosin F controls actin organization and dynamics in Toxoplasma gondii	8
AP-4 regulates neuronal lysosome composition, function, and transport via regulating export of critical lysosome receptor proteins at the trans-Golgi network	8
Inositol 1, 4, 5-trisphosphate receptor is required for spindle assembly in Xenopus oocytes	8
Label-free single-cell live imaging reveals fast metabolic switch in T lymphocytes	7
The RNA-binding protein HNRNPA2B1 regulates neurite RNA abundance and motor-dependent cargo transport	7
Computational simulations reveal that Abl activity controls cohesiveness of actin networks in growth cones	7
FARL-11 (STRIP1/2) is required for sarcomere and sarcoplasmic reticulum organization in C. elegans	7
Nuclear basket proteins regulate the distribution and mobility of nuclear pore complexes in budding yeast	7
TORC1-dependent sorting of PI(3,5)P 2 is required for vacuole membrane remodeling and signaling endosome formation	7
The RhoGEF Trio regulates the formation of tensile linear endothelial junctions to improve barrier function	7
Matrix obstructions cause multiscale disruption in collective epithelial migration by suppressing leader cell function	7
Actin- and microtubule-based motors contribute to clathrin-independent endocytosis in yeast	7
Efficient fusion requires a membrane anchor on the vacuolar Qa-SNARE	7
Yeast cell fusion is mediated by spatially regulated secretion	7
The PCM scaffold enables RNA localization to centrosomes	7
Lateral and longitudinal compaction of PRC1 overlap zones drives stabilization of interzonal microtubules	7
Regulation of condensin II by self-suppression and release mechanisms	7