Medicinal Chemistry Research

Article	Citations
Monoamine oxidase inhibition by thiazole derivatives substituted with the benzenesulfonamide moiety	105
Computer-aided design, synthesis and evaluation of new SARS-CoV-2 Mpro inhibitors based on 1,5,6,7-tetrahydro-4H-indazol-4-one scaffold	93
Novel imino-thiazoloquinoxaline derivatives against renal cell carcinoma: less radiation-damaging approach	72
Synthesis of the dibenzylbutane lignan LCA derivatives and evaluation of their anti-inflammatory activities	59
Synthesis, characterization and in vitro antitumor activity of asiatic acid derivatives	55
Potent α-glucosidase inhibitory activity of inoscavin A from fruiting bodies of Fulvifomes fastuosus: Mechanism of action, molecular docking and ADMET	51
Synthesis of berberine derivatives and their antiviral activity toward respiratory syncytial virus	48
Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal m	45
Targeting cAMP signaling and phosphodiesterase 4 for liver disease treatment	40
Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids	40
Carbamoyl flavonoids as dual inhibitors of acetylcholinesterase and monoacylglycerol lipase: synthesis, in vitro evaluation, and computational studies	38
Asciminib: first FDA approved allosteric inhibitor of BCR-ABL1 for the treatment of chronic myeloid leukemia	37
Antibacterial, antifungal activities and toxicity of new synthetic fatty acid salicylate esters	35
Evaluation of a series of nucleoside analogs as effective anticoronaviral-2 drugs against the Omicron-B.1.1.529/BA.2 subvariant: A repurposing research study	33
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3β,12β,25-triol derivatives as α-glucosidase and PTP1B inhibitors	33
Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic antic	32
Synthesis and antitumor activity evaluation in vitro of 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole	32
Glutathione and glutathione disulfide – their biomedical and pharmaceutical applications	32
Design, synthesis, and antitumor activity evaluation of carbazole derivatives with potent HDAC inhibitory activity	32
Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent	32
Synthesis of tetrahydro-β-carboline analogs with N11 modifications and study of their antimalarial activities	31
Screening of small molecule compounds targeting hnRNPA2 protein	31
Design and synthesis of diphenyl-1H-imidazole analogs targeting Mpro/3CLpro enzyme of SARS-CoV-2	29
Enantioselectivity of pinene against Leishmania amazonensis	29
A versatile strategy for the synthesis of various lumazine peptides	29

Evaluation of benzoylacetonitriles as novel anti-neuroinflammatory agents	27
Plant-derived pyroptosis inducers as a therapeutic strategy in drug-resistant cancers	26
Pyrrolobenzodiazepines: natural sources, therapeutic uses, and future in neurological treatments	26
Utilizing mechanistic organic chemistry training to study drug metabolism in preclinical drug discovery/development	26
Synthesis and potential antimicrobial activity of novel α-aminophosphonates derivatives bearing substituted quinoline or quinolone and thiazole moieties	23
Synthesis, crystal structure, and anticancer activity of organotin(IV) complexes based on chlorine substituted aryl ligands	23
Design, Synthesis, and biological evaluation of pyrazolo-benzothiazole derivatives as a potential therapeutic agent for the treatment of Alzheimer’s disease	22
Synthesis, inhibition effects, molecular docking and theoretical studies as Paraoxonase 1 (PON1) inhibitors of novel 1,4-dihydropyridine substituted sulfonamide derivatives	22
Contrasting effect of different crowding agents on pseudoknot RNA stability	21
Medicinal uses, phytochemistry, pharmacology, and taxonomy of Poygonum aviculare L.: a comprehensive review	20
Semi-synthesis and cytotoxicity evaluation of pyrimidine, thiazole, and indole analogues of argentatins A–C from guayule (Parthenium argentatum) resin	20
Recent advances in triazole-benzenesulfonamide hybrids and their biological activities	20
Pyrrolo[2,1-f][1,2,4]triazine: a promising fused heterocycle to target kinases in cancer therapy	19
Synthesis of nitrogen-containing oleanolic acid derivatives as carbonic anhydrase and acetylcholinesterase inhibitors	19
Synthesis and biological evaluation of esculetin derivatives as potential anti-HBV agents	18
Exploring thiazole-linked thioureas using alkaline phosphatase assay, biochemical evaluation, computational analysis and structure–activity relationship (SAR) studies	18
Dual-PROTACs based on natural product derivative potassium dehydrographolide succinate: design, synthesis, and antitumor activity of a novel EGFR degrader	18
Synthetic studies toward a simplified eleuthoside core	17
Pks 13 inhibitors—a promising target for future antitubercular agents	17
α-Glucosidase inhibitory activities of aromatic compounds from the rhizomes of Alpinia galanga	17
A vitamin D C/D ring-derived compound with cytotoxicity	17
Design, synthesis and evaluation of salicylic acid-donepezil hybrids as functional agents for the treatment of Alzheimer’s disease	17
Development of new donepezil analogs: synthesis, biological screening and in silico study rational	16
Novel conjugated 5-alkenyl rhodanine tethered 1,4-benzodioxane derivatives as dual-chitinases inhibitors to hinder the growth of Asian corn borer	16
Synthesis and in vitro anti-trypanosomal evaluation of quinolone hydrazide analogues	16
Polyketides from Neohelicosporium griseum: structure assignment and bioactivity investigation	16
Synthesis, bacteria activity and molecular simulation of D-galactose-conjugated thiosemicarbazones of 3-aryl-4-formylsydnones	15
1,2,3-triazenes and 1,2,3-triazoles as antileishmanial, antitrypanosomal, and antiplasmodial agents	15
Molecular hybridization method for obtaining paeonol-based fibrate derivatives with potent lipid-lowering and hepatoprotective activity	15
Novel indanone-chalcone esters with potential anti-Alzheimer effects designed using hybridization and bioisosteric replacement approaches	15
Synthesis and biological assessment of triazolo-quinazoline carbothioamide derivatives for p38 MAP kinase inhibition: in-silico and in-vitro approaches	15
Role of natural secondary metabolites as HIF-1 inhibitors in cancer therapy	15
A Click Synthesis, Molecular Docking and Biological Evaluation of 1,2,3-triazoles-benzoxazepine hybrid as potential anticancer agents	15
Design, synthesis and antitumor activity evaluation of 2,4,6-trisubstituted quinazoline derivatives containing piperidine moiety	15
In vitro cytotoxicity evaluation of triphenylphosphonium (TPP) conjugates of some acetylenated nucleic bases and their analogues	14
Synthesis and biological evaluation of coumarin derivatives as anti-lung adenocarcinoma agents via induction of apoptosis and autophagy: in vitro and in vivo studies	14
Antivirulence therapy: type IV pilus as a druggable target for bacterial infections	14
The metabolic fate of izencitinib, a gut-selective pan-JAK inhibitor, in humans. Identification of unusual fecal metabolites and implications for MIST evaluation	13
Design, synthesis and evaluation of aurone and indanone derivatives as novel antitumor agents	13
Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides as selective dopamine D3 receptor ligands	13
Rehmannia glutinosa polysaccharides: a review on structure-activity relationship and biological activity	13
Insights on synthetic strategies and structure-activity relationship of donepezil and its derivatives	13
Antitumor studies on celastrol and its derivatives as RORα agonists and RORγ inhibitors based on Alphafold reverse docking strategy	13
Synthesis, antiviral evaluation, molecular docking study and cytotoxicity of 5′-phosphorylated 1,2,3-triazolyl nucleoside analogues with thymine and 6-methyl uracil moieties	13
Synthesis, characterization, and anticancer activity of syringaldehyde-derived chalcones against female cancers	13
Glycyrrhizin and its derivatives: an emerging secondary metabolite arsenal of Glycyrrhiza glabra	12
Synthesis and biological evaluation of triazole alcohols containing an indole-3-methyl(phenyl)amino side chain against fluconazole-resistant Candida albicans	12
Biological evaluation of imidazopyridine derivatives as potential anticancer agents against breast cancer cells	12
Novel 2-aminopyrimidine Schiff bases as possible GABA-AT inhibitors: molecular docking, MAOS, and pharmacological screening	12
A potent therapeutic scaffold fusing quinazolinone/melatonin for future colorectal cancer interventions: design, one-pot synthesis, biological and ADME-tox modeling studies	12

Design and synthesis of potential fungicidal compounds derived from natural products, (-)-menthol and (-)-borneol	12
Designations of new biological drugs	12
Discovery of novel HCV inhibitors: design, synthesis and biological activity of phthalamide derivatives	11
Synthesis, in vitro activity, and molecular docking of caffeic acid and resveratrol derivatives against Alzheimer’s disease-related enzymes	11
Discovery of potent maternal embryonic leucine zipper kinase (MELK) inhibitors of novel chemotypes using structure-based pharmacophores	11
Antiproliferative effect, cell cycle arrest and apoptosis generation of novel 6-substituted N5-formyltetrahydropyrido[3,2-d]pyrimidine derivatives	11
Synthesis and pharmacological evaluation of new disulfides linked to 1,2,4-triazole bearing urea moiety	11
Synthesis and in vitro biological activity of chalcone derivatives as potential antiparasitic agents	11
Design, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects	10
Structure related α-glucosidase inhibitory activity and molecular docking analyses of phenolic compounds from Paeonia suffruticosa	10
Discovery of mobocertinib, a new irreversible tyrosine kinase inhibitor indicated for the treatment of non-small-cell lung cancer harboring EGFR exon 20 insertion mutations	10
Discovery of novel pterostilbene/biphenyl tethered 5-FU based conjugates targeting colorectal cancer: synthesis, cytotoxic and ADMET modeling studies	10
Kaempferia diterpenoids and flavonoids: an overview on phytochemistry, biosynthesis, synthesis, pharmacology, and pharmacokinetics	10
Pharmacological assessment of disulfide–triazine hybrids: synthesis, enzyme inhibition, and molecular docking study	10
Discovery of α-methylene-γ-lactone-δ-epoxy derivatives with anti-cancer activity: synthesis, SAR study, and biological activity	10
Synthesis and effects of ginkgolides and ginkgolide B derivatives on platelet activating factor induced platelet aggregation in rabbits	9
Hit-to-lead optimization of amino-carboxamide benzothiazoles as LSD1 inhibitors	9
An insight into prodrug strategy for the treatment of Alzheimer’s disease	9
Synthesis, antiproliferative, and antimicrobial properties of novel phthalimide derivatives	9
Assessment of the α-glucosidase and α-amylase inhibitory potential of Paliurus spina-christi Mill. and its terpenic compounds	9
CYP3A4 drug metabolism considerations in pediatric pharmacotherapy	9
4,5-diazafenylfluorene-rhodanine conjugates promote anoikis in A375 cells via inhibiting PPAR-γ expression	9
Polyalthia longifolia: phytochemistry, ethnomedicinal importance, nutritive value, and pharmacological activities review	9
Lipase inhibitory activity of constituents of Physalis glutinosa and Physalis latiphysa	8
Sphingosine 1-phosphate receptor modulators for the treatment of inflammatory bowel disease and other immune-mediated diseases	8
Synthesis of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides and their evaluation as D3 receptor ligands	8
Synthesis, theoretical investigations and biological evaluation of ibuprofen drug hybrids	8
Discovery of novel acridine-chalcone hybrids with potent DNA binding and antiproliferative activity against MDA-MB-231 and MCF-7 cells	8
Stable isotope applications in drug development and the elucidation of mechanisms of drug metabolism	8
Design, synthesis, and neuroprotective activity of salidroside-based dual inhibitors of selective monoamine oxidase B and amyloid-β aggregation	8
Design, synthesis, characterization and cytotoxic activity of new ortho-hydroxy and indole-chalcone derivatives against breast cancer cells (MCF-7)	7
In silico drug discovery: a machine learning-driven systematic review	7
Synthesis and inhibitory activity against enzymes responsible for Type 2 diabetes mellitus of lactose-conjugated thiosemicarbazones from substituted acetophenones	7
Structural optimization and biological evaluation of quinoline/naphthalene-based glyoxalase-I inhibitors as anti-cancer candidates	7
Exploring the latest breakthroughs in rhodesain inhibitors for African trypanosomiasis	7
Drug repositioning of benzimidazole anthelmintics in the treatment of cryptococcosis: a review	7
4-Phenylcoumarins from Mesua ferrea with selective CYP1B1 inhibitory activity	7
Design, synthesis, in vitro evaluation, and molecular dynamics simulation studies of novel coumarin-acetohydrazide Schiff base derivatives as urease enzyme inhibitors	7
The emerging role of proteolysis targeting chimeras (PROTACs) in the treatment of Alzheimer’s disease	7
The potential of chalcone derivatives as human carbonic anhydrase inhibitors in the therapy of glaucoma	7
Sesquiterpene lactones isolated from Carpesium abrotanoides L. by LC–MS combined with HSCCC inhibit liver cancer through suppression of the JAK2/STAT3 signaling pathway	7
Tranilast-tyrosine hybrid molecule exhibits dual activity: suppression of epithelial-mesenchymal transition and induction of cytotoxicity in cancer cells	7
A glance into Schiff-based α-glucosidase inhibitors in medicinal chemistry	7
Acetylcholinesterase Inhibitors from Carbamate and Benzo-fused Heterocyclic Scaffolds: Promising Therapeutics for Alzheimer’s Disease	7
ATP-hydrolyzing, DNA-damaging and cytotoxic activities of peptide-targeted cobalt(III) complex with diethylentriamine	7
Synthesis, and docking studies of arylhydrazone compounds and evaluation of their platelet aggregation inhibitory effect and cytotoxicity	7
Synthesis of 6-dialkylaminopyrimidine carboxamide analogues and their anti-tubercular properties	7
Synthesis and evaluation of tetrahydrobenzo[cd]indole derivatives as glycogen phosphorylase inhibitors	7
Design, synthesis, stereochemical characterization, in vitro α-glucosidase, and α-amylase inhibition and in silico studies of novel pyrazole-hydrazide hydrazones	7
The potential of major kavalactones in modulating cytochrome P450 enzymes	7
Engelheptanoxides behave as liver X receptor α agonists	7
Synthesis, characterization and biological evaluation of formononetin derivatives as anticancer agents	7
Ferrocene-based compounds: promising anticancer and antimalarial agents in modern therapeutics	7
Synthesis, structure-activity relationship and evaluation of antifungal activity of tryptanthrin derivatives against drug-resistant Candida albicans	7
Does the negatively charged phosphate backbone contribute to stabilize the complex between cationic organic molecules and G-quadruplex structures? From guessing to calculating	7
In vitro antiproliferative activity of Parrotia persica exclusive gallotannin	7
Harnessing the necessary nitrogen atom in chemical biology and drug discovery	6
CO as a potential therapeutic agent: an initial investigation of dosing and concentration dynamics in solution	6
A reliable and automated synthesis of 6-[18F]fluoro-L-DOPA and the clinical application on the imaging of congenital hyperinsulinism of infants	6
The use of single-molecule FRET for the characterization of Holliday junctions containing human telomeric DNA: a methodological approach for nanoscale distance, mobility, and stability measurements	6
An in vitro and in silico α-amylase/α-glucosidase/protein tyrosine phosphatase 1 beta & radical scavenging profiling of the 3,5,7-tricarbo substituted 1H-indazoles	6
Benzocaine-N-acylindoline conjugates: synthesis and antiviral activity against Coxsackievirus B3	6
Substituted furan-carboxamide and Schiff base derivatives as potential hypolipidemic compounds: evaluation in Triton WR-1339 hyperlipidemic rat model	6
Novel vitamin K3 analogs containing 3-N-substituted aromatic and piperazine rings with selective in vitro anticancer activity against HeLa, U87 MG, and MCF-7 cells	6
Prenylated flavonoids icariin and icaritin for drug discovery: structural modifications and bioactivity studies	6
SARS-CoV-2 3CL-protease inhibitors derived from ML300: investigation of P1 and replacements of the 1,2,3-benzotriazole	6
Synthesis and analgesic potential of 4-[4–chloro-3- (trifluoromethyl)-phenyl]-4-piperidinol analogues against pain model in mice	6
Anticancer potential of nicotinonitrile derivatives as PIM-1 kinase inhibitors through apoptosis: in vitro and in vivo studies	6
Translating G-quadruplex ligands from bench to bedside: a Stephen Neidle’s legacy	6
Synthesis, pharmacological and molecular docking investigations of 1,3,4-oxadiazole-5-thionyl derivatives of extracted cis-clerodane diterpenoid from Cistus monspeliensis	6
A novel sight of the primary active compounds from Umbelliferae: focusing on mitochondria	6
2-substituted 4-aminoquinazoline derivatives as potential dual inhibitors of EGFR and HER2: an in silico and in vitro study	6
CO prodrugs: a new scaffold of adamantane-fused norbornen-7-ones with tunable water solubility	6
Design, synthesis and anti-tumor activity evaluation of 4,6,7-substitute quinazoline derivatives	6
Hybrid-based design and biological evaluation of quinoline-benzoylhydrazine based derivatives as α-glucosidase inhibitors	6
Underpinning the role of natural products against cisplatin-induced nephrotoxicity in rodent models	6
Research progress on antidiabetic activity of apigenin derivatives	6
Anticancer and antimicrobial activities of new thiazolyl-urea derivatives: gene expression, DNA damage, DNA fragmentation and SAR studies	6
Glycosylated triptolide affords a potent in vivo therapeutic activity to hepatocellular carcinoma in mouse model	6
New tetracyclic systems integrated thienopyridine scaffold as an anti-dementia lead: in silico study and biological screening	6

Identification of α-mangostin as a potent inhibitor of β-lactamase OXA-48	6
Optimization of clofibrate with natural product sesamol for reducing liver injury induced by acetaminophen	6
Development of novel fluoro-substituted rivastigmine derivatives as selective AChE inhibitors for the treatment of AD	6
Synthesis of simplified didehydro-cortistatin A derivatives as anti-proliferative agents	6
Bioassay-guided fractionations of Cannabis sativa extract and HPLC-assisted purifications of anti-proliferative active fractions lead to the isolation of 16 known and one new phytomolecule and their i	6
Esters and amides of benzofuroxan-1-N–oxide derivatives as trypanocidal and leishmanicidal agents	6
Morpholinated curcuminoids against urinary bladder cancer cells: synthesis and anticancer evaluation	5
Platanic acid derived amides are more cytotoxic than their corresponding oximes	5
Synthesis and evaluation of new 2-oxo-1,2-dihydroquinoline-3-carboxamides as potent inhibitors against acetylcholinesterase enzyme	5
Translational insights from species differences in the metabolism of triclosan	5
Synthesis and anti-leishmanial activities of uniflorol analogues	5
Phytochemical constituents isolated from Silene popovii Schischk	5
Novel Benzo[4,5]imidazo[1,2-a]pyrimidine derivatives as selective Cyclooxygenase-2 Inhibitors: Design, synthesis, docking studies, and biological evaluation	5
Discovery of novel fatty acid amide hydrolase (FAAH) inhibitors as anti-Alzheimer’s agents through pharmacophore-based virtual screening, molecular docking and experimental validation	5
Design, synthesis, and fungicidal activity of pyrimidinamine derivatives containing pyridin-2-yloxy moiety	5
Insights into the α-amylase and α-glucosidase inhibition mechanism of 4-(4-hydroxyphenyl)-but-3-en-2-one from Scutellaria barbata D. Don: enzymatic kinetics, fluorescence spectroscopy and computationa	5
Design, synthesis, in vitro evaluation, and docking studies on ibuprofen derived 1,3,4-oxadiazole derivatives as dual α-glucosidase and urease inhibitors	5
Design and synthesis of O-glycoside derivatives with promising antidiabetic and anticancer potential	5
Preliminary structure−activity relationships analysis on N-(3,5-dichlorophenyl)-4,5-dihydronaphtho[1,2-d]thiazol-2-amine, a disruptor of mycobacterial energetics	5
New indolo-β-lactam hybrids as potential anticancer and anti-inflammatory agents	5
Correction: Substituted furan-carboxamide and Schiff base derivatives as potential hypolipidemic compounds: evaluation in Triton WR-1339 hyperlipidemic rat model	5
Investigation of the monoamine oxidase inhibition properties of benzoxathiolone derivatives	5
The emergence of sulfo-click amidation in kinetic target-guided synthesis	5
A second life for the crystallographic structure of Berenil-dodecanucleotide complex: a computational revisitation thirty years after its publication	5
Promising Schiff bases in antiviral drug design and discovery	5
Biocatalytic potential of microbial CYP450s in the degradation of selected environmental pollutants	5
Withania coagulans: a comprehensive exploration of its botanical, phytochemical, and pharmacological properties	5
The history, mechanism, and perspectives of nirmatrelvir (PF-07321332): an orally bioavailable main protease inhibitor used in combination with ritonavir to reduce COVID-19-related hospitalizations	5
An update on the discovery and development of reversible covalent inhibitors	5
Iron porphyrin-mediated production of carbon monoxide from phenylpyruvic acid: from potential therapeutic and diagnostic use to physiological implications	5
Future challenges and opportunities with fluorine in drugs?	5
Correction to: Structure-activity relationships and pharmacokinetic evaluation of L-cystine diamides as L-cystine crystallization inhibitors for cystinuria	5
N-Phosphorylation of daunorubicin—synthetic approaches and antiproliferative properties of the products	5
Glutathione transferases in cats and dogs: diversity, structure, and function	5
Acyl glucuronides–mediators of drug-induced toxicities?	5
Design and synthesis of novel cycloalkanecarboxamide parabanic acid hybrids as anticonvulsants	5
Naturally occurring plant-derived sulfonated and sulfated saponins from 1983 to 2024	5
The anti-inflammatory effects of iridoid glycosides: a comprehensive review of mechanisms of action and structure-activity relationships	5
Lenacapavir, a first-in-class, long-acting capsid inhibitor approved for both HIV-1 treatment and prevention	5
Evaluation of homodimer 99mTc-HYNIC-E(SSSLTVPWY)2 peptide on HER2-over expressed breast cancer cells	5
Exploring nucleoside analogs: key targets in the viral life cycle - advancing strategies against SARS-CoV-2	5
Recent updates on thienopyrimidine derivatives as anticancer agents	5
Recent pharmacological insights about imidazole hybrids: a comprehensive review	5
Synthesis, biological evaluation, and molecular modeling studies of a new series of imidazothiazole or imidazooxazole derivatives as inhibitors of ectonucleoside triphosphate diphosphohydrolases (NTPD	5
Thiophene ring-opening reactions. Part VII: synthesis and antitumor, anti-inflammatory, and antioxidant properties of 1,3,4‒thiadiazoline‒6-sulfanylthiopyran-4(1H)-one hybrids	5
Design and synthesis of aminothiazole-benzazole based amide: antiproliferative, antimigration activity and molecular docking studies	5
The mechanism of resistance in Escherichia coli to ridinilazole and other antibacterial head-to-head bis-benzimidazole compounds	5
Discovery of oxazolidinone-based heterocycles as subtype selective sigma-2 ligands	4
Triphenylphosphonium (TPP) conjugates of 1,2,3-triazolyl nucleoside analogues. Synthesis, cytotoxicity and antimicrobial activity	4
Synthesis and biological evaluation of sulfamate derivatives as inhibitors of carbonic anhydrases II and IX	4
Design, synthesis and antitumor activity evaluation of 5-cyano-2,4,6-substituted pyrimidine derivatives containing acrylamide group	4
Position switch of phenylthiazoles: novel compounds with promising anti-MRSA USA300	4
From the ethnomedicinal plants in northern Indochina to the development of novel anti-cancer therapeutic agents	4
Evaluation of chemical constituents of Rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia) as adenosine A1/A2A receptor ligands	4
Facile access to novel furoyl-based amide retroisoster inhibitors of LuxR-regulated quorum sensing: conformation analysis and docking studies	4
Phenoxyalkyl cyclic and acyclic amine derivatives: what do they teach us about scaffold-based drug design?	4
FTase inhibitors and cancer: prospects for use in targeted therapies	4
α-Glucosidase and cholinesterase inhibiting potential of a series of semisynthetic nitrogen triterpenic derivatives	4
Nafithromycin (MIQNAF®): ultramodern lactone ketolide designed to treat community acquired bacterial pneumonia (CABP)	4
Synthesis, urease inhibitory and anticancer evaluation of glucosamine-sulfonylurea conjugates	4
Vital residues-orientated rational design of butenolide inhibitors targeting Of ChtI	4
Synthesis, cytotoxicity, Pan-HDAC inhibitory activity and docking study of new N-(2-aminophenyl)-2-methylquinoline-4-carboxamide and (E)-N-(2-aminophenyl)-2-styrylquinoline-4-carboxamide derivatives a	4
Current updates on EGFR and HER2 tyrosine kinase inhibitors for the breast cancer	4
Design and synthesis of novel factor XIa Inhibitors with bicyclic isoquinoline and naphthalene fragments	4
Recent advances in structural types and medicinal chemistry of PARP-1 inhibitors	4
Targeting MDM2 for the development of a new cancer therapy: progress and challenges	4
Design, synthesis and antitumor activity study of tubulin/HDAC6 dual targeting inhibitor	4
Design, synthesis, and biological evaluation of novel 2-acetylphenol-rivastigmine hybrids as potential multifunctional agents for the treatment of Alzheimer’s disease	4
Integrating omics data for personalized medicine in treating psoriasis	4
Design, synthesis, molecular docking study and molecular dynamics simulation of new coumarin-pyrimidine hybrid compounds having anticancer and antidiabetic activity	4
Identification and evaluation of potent AAK1 inhibitors through structure-based pharmacophores, virtual screening and bioassay screening	4
Social environment during fear extinction alters the binding of [3H] MK-801 to N-methyl-D-aspartic acid receptors in Wistar-Kyoto and Wistar rats	4
Correction: Bioassay-guided fractionations of Cannabis sativa extract and HPLC-assisted purifications of anti-proliferative active fractions lead to the isolation of 16 known and one new phytomolecule	4
Design, synthesis and antiproliferative activity of ACY-1215 analogs as potent selective histone deacetylases 6 inhibitors	4
Self-assembled amphiphilic bipyridine and bisquinoline cisplatin analogues: synthesis and anticancer properties	4
Design & synthesis of hybrid pharmacophore of β-lactam, 1,8-naphthyridine, and secondary amines; Discover their in vitro antimicrobial, anticancer properties & DFT and ADMET prediction studies	4
Lead change of a HIF-2α antagonist guided by multiparameter optimization and utilization of an Olp→π*Ar interaction	4
Exploring the potential of isatin hybrids as anticancer agents: recent advances and future prospective	4
Isatin derivatives as broad-spectrum antiviral agents: the current landscape	4
Gallic acid derived diarylpropanones exhibit synergistic antibacterial activities	4
Investigating novel tubulin polymerization inhibitors: design, synthesis, LC/MS cellular permeability, in silico studies, and in vitro assessment	4
Design, synthesis and antifungal study of novel 2-aryl-3,4-dihydroisoquinolin-2-ium salts containing benzoate moieties	4
Design, synthesis and antitumor activity evaluation of 4,6,7-trisubstituted quinazoline derivatives containing benzothiazole moiety	4
Design, synthesis and profiling of proteolysis-targeting chimeras (PROTACs) as CDK4/6 degraders	4
Cyclohepta[b]pyran: an important scaffold in biologically active natural products	4
Design, synthesis and assay of 2-(4-phenylpiperazin-1-yl)pyrimidine-5- carboxamide derivatives as acetylcholinesterase inhibitors	4
Structure-based optimization of aminothiadiazole inhibitors of AKT	4
Correction: Anticancer therapeutic potential of silibinin: current trends, scope and relevance	4
Synthesis and antitumor activity of novel silibinin and 2,3-dehydrosilybin derivatives with carbamate groups	4
A novel class of indole derivatives: enhanced bioavailability, permeability, and antioxidant efficacy for thromboembolic disease therapy	4
A review on efficacy of phytochemicals in the treatment of trypanosomiasis	4
Phytochemistry and pharmacological activities of Tinospora genus: An updated review	4
Design, synthesis, and biological evaluation of catalpalactone and its analogs	4
Discovery of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of adaptor protein 2-associated kinase 1 for the treatment of pain	4
Garcidepsidone B from Garcinia parvifolia: antimicrobial activities of the medicinal plants from East and North Kalimantan against dental caries and periodontal disease pathogen	4