OOIR: Observatory of International Research

Papers

(The H4-Index of Medicinal Chemistry Research is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Synthesis of the dibenzylbutane lignan LCA derivatives and evaluation of their anti-inflammatory activities	91
Acetylcholinesterase inhibition, molecular docking and ADME prediction studies of new dihydrofuran-piperazine hybrid compounds	90
Monoamine oxidase inhibition by thiazole derivatives substituted with the benzenesulfonamide moiety	89
Computer-aided design, synthesis and evaluation of new SARS-CoV-2 Mpro inhibitors based on 1,5,6,7-tetrahydro-4H-indazol-4-one scaffold	66
Novel imino-thiazoloquinoxaline derivatives against renal cell carcinoma: less radiation-damaging approach	50
Ellagic acid (EA), a tannin was isolated from Eucalyptus citriodora leaves and its anti-inflammatory activity	48
Synthesis, characterization and in vitro antitumor activity of asiatic acid derivatives	45
Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent	44
Carbamoyl flavonoids as dual inhibitors of acetylcholinesterase and monoacylglycerol lipase: synthesis, in vitro evaluation, and computational studies	35
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3β,12β,25-triol derivatives as α-glucosidase and PTP1B inhibitors	34
Evaluation of a series of nucleoside analogs as effective anticoronaviral-2 drugs against the Omicron-B.1.1.529/BA.2 subvariant: A repurposing research study	34
Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids	33
Targeting cAMP signaling and phosphodiesterase 4 for liver disease treatment	32
Design, synthesis, and antitumor activity evaluation of carbazole derivatives with potent HDAC inhibitory activity	31
Antibacterial, antifungal activities and toxicity of new synthetic fatty acid salicylate esters	31
Synthesis of hydrazine containing piperazine or benzimidazole derivatives and their potential as α-amylase inhibitors by molecular docking, inhibition kinetics and in vitro cytotoxicity activity studi	30
Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal m	30
Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic antic	28
Synthesis and antitumor activity evaluation in vitro of 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole	27
Glutathione and glutathione disulfide – their biomedical and pharmaceutical applications	27
Asciminib: first FDA approved allosteric inhibitor of BCR-ABL1 for the treatment of chronic myeloid leukemia	26
Inhibition of protein kinases by proton pump inhibitors: computational screening and in vitro evaluation	24
Screening of small molecule compounds targeting hnRNPA2 protein	24
Pyrrolo[2,1-f][1,2,4]triazine: a promising fused heterocycle to target kinases in cancer therapy	24
Synthesis of berberine derivatives and their antiviral activity toward respiratory syncytial virus	24

Synthesis of tetrahydro-β-carboline analogs with N11 modifications and study of their antimalarial activities