OOIR: Observatory of International Research

Papers

(The H4-Index of Medicinal Chemistry Research is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Synthesis, characterization and in vitro antitumor activity of asiatic acid derivatives	120
Potent α-glucosidase inhibitory activity of inoscavin A from fruiting bodies of Fulvifomes fastuosus: Mechanism of action, molecular docking and ADMET	104
Targeting cAMP signaling and phosphodiesterase 4 for liver disease treatment	88
Synthesis and antitumor activity evaluation in vitro of 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole	78
Computer-aided design, synthesis and evaluation of new SARS-CoV-2 Mpro inhibitors based on 1,5,6,7-tetrahydro-4H-indazol-4-one scaffold	68
Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent	62
Design, synthesis, and antitumor activity evaluation of carbazole derivatives with potent HDAC inhibitory activity	58
Carbamoyl flavonoids as dual inhibitors of acetylcholinesterase and monoacylglycerol lipase: synthesis, in vitro evaluation, and computational studies	54
Evaluation of a series of nucleoside analogs as effective anticoronaviral-2 drugs against the Omicron-B.1.1.529/BA.2 subvariant: A repurposing research study	51
Antibacterial, antifungal activities and toxicity of new synthetic fatty acid salicylate esters	51
Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic antic	47
Asciminib: first FDA approved allosteric inhibitor of BCR-ABL1 for the treatment of chronic myeloid leukemia	44
Synthesis of the dibenzylbutane lignan LCA derivatives and evaluation of their anti-inflammatory activities	39
Anticancer activity of amide and ester derivatives of the ent-labdane 2α-hydroxyeperuic acid obtained via sonochemical synthesis	39
Synthesis of berberine derivatives and their antiviral activity toward respiratory syncytial virus	38
Monoamine oxidase inhibition by thiazole derivatives substituted with the benzenesulfonamide moiety	38
Novel imino-thiazoloquinoxaline derivatives against renal cell carcinoma: less radiation-damaging approach	35
Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids	34
Glutathione and glutathione disulfide – their biomedical and pharmaceutical applications	34
Synthesis of tetrahydro-β-carboline analogs with N11 modifications and study of their antimalarial activities	33
Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal m	33
Screening of small molecule compounds targeting hnRNPA2 protein	33
Contrasting effect of different crowding agents on pseudoknot RNA stability	30
Design and synthesis of diphenyl-1H-imidazole analogs targeting Mpro/3CLpro enzyme of SARS-CoV-2	30
A versatile strategy for the synthesis of various lumazine peptides	29

Plant-derived pyroptosis inducers as a therapeutic strategy in drug-resistant cancers	29
Evaluation of benzoylacetonitriles as novel anti-neuroinflammatory agents	29