OOIR: Observatory of International Research

Papers

(The H4-Index of Medicinal Chemistry Research is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Monoamine oxidase inhibition by thiazole derivatives substituted with the benzenesulfonamide moiety	110
Computer-aided design, synthesis and evaluation of new SARS-CoV-2 Mpro inhibitors based on 1,5,6,7-tetrahydro-4H-indazol-4-one scaffold	96
Synthesis, characterization and in vitro antitumor activity of asiatic acid derivatives	75
Synthesis and antitumor activity evaluation in vitro of 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole	67
Potent α-glucosidase inhibitory activity of inoscavin A from fruiting bodies of Fulvifomes fastuosus: Mechanism of action, molecular docking and ADMET	60
Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal m	52
Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids	49
Asciminib: first FDA approved allosteric inhibitor of BCR-ABL1 for the treatment of chronic myeloid leukemia	48
Synthesis of the dibenzylbutane lignan LCA derivatives and evaluation of their anti-inflammatory activities	47
Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic antic	45
Targeting cAMP signaling and phosphodiesterase 4 for liver disease treatment	43
Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent	42
Synthesis of berberine derivatives and their antiviral activity toward respiratory syncytial virus	38
Design, synthesis, and antitumor activity evaluation of carbazole derivatives with potent HDAC inhibitory activity	38
Novel imino-thiazoloquinoxaline derivatives against renal cell carcinoma: less radiation-damaging approach	37
Glutathione and glutathione disulfide – their biomedical and pharmaceutical applications	36
Antibacterial, antifungal activities and toxicity of new synthetic fatty acid salicylate esters	34
Evaluation of a series of nucleoside analogs as effective anticoronaviral-2 drugs against the Omicron-B.1.1.529/BA.2 subvariant: A repurposing research study	33
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3β,12β,25-triol derivatives as α-glucosidase and PTP1B inhibitors	33
Design and synthesis of diphenyl-1H-imidazole analogs targeting Mpro/3CLpro enzyme of SARS-CoV-2	32
Carbamoyl flavonoids as dual inhibitors of acetylcholinesterase and monoacylglycerol lipase: synthesis, in vitro evaluation, and computational studies	32
Screening of small molecule compounds targeting hnRNPA2 protein	32
Synthesis of tetrahydro-β-carboline analogs with N11 modifications and study of their antimalarial activities	32
Evaluation of benzoylacetonitriles as novel anti-neuroinflammatory agents	29
A versatile strategy for the synthesis of various lumazine peptides	29

Utilizing mechanistic organic chemistry training to study drug metabolism in preclinical drug discovery/development	27
Pyrrolobenzodiazepines: natural sources, therapeutic uses, and future in neurological treatments	27