OOIR: Observatory of International Research

Papers

(The H4-Index of Medicinal Chemistry Research is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Synthesis of the dibenzylbutane lignan LCA derivatives and evaluation of their anti-inflammatory activities	94
Acetylcholinesterase inhibition, molecular docking and ADME prediction studies of new dihydrofuran-piperazine hybrid compounds	92
Monoamine oxidase inhibition by thiazole derivatives substituted with the benzenesulfonamide moiety	68
Computer-aided design, synthesis and evaluation of new SARS-CoV-2 Mpro inhibitors based on 1,5,6,7-tetrahydro-4H-indazol-4-one scaffold	54
Novel imino-thiazoloquinoxaline derivatives against renal cell carcinoma: less radiation-damaging approach	51
Synthesis, characterization and in vitro antitumor activity of asiatic acid derivatives	46
Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent	44
Carbamoyl flavonoids as dual inhibitors of acetylcholinesterase and monoacylglycerol lipase: synthesis, in vitro evaluation, and computational studies	37
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3β,12β,25-triol derivatives as α-glucosidase and PTP1B inhibitors	36
Targeting cAMP signaling and phosphodiesterase 4 for liver disease treatment	35
Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids	35
Synthesis and antitumor activity evaluation in vitro of 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole	34
Glutathione and glutathione disulfide – their biomedical and pharmaceutical applications	32
Antibacterial, antifungal activities and toxicity of new synthetic fatty acid salicylate esters	31
Asciminib: first FDA approved allosteric inhibitor of BCR-ABL1 for the treatment of chronic myeloid leukemia	31
Design, synthesis, and antitumor activity evaluation of carbazole derivatives with potent HDAC inhibitory activity	30
Evaluation of a series of nucleoside analogs as effective anticoronaviral-2 drugs against the Omicron-B.1.1.529/BA.2 subvariant: A repurposing research study	30
Ellagic acid (EA), a tannin was isolated from Eucalyptus citriodora leaves and its anti-inflammatory activity	30
Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal m	30
Synthesis of berberine derivatives and their antiviral activity toward respiratory syncytial virus	29
Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic antic	28
Synthesis of tetrahydro-β-carboline analogs with N11 modifications and study of their antimalarial activities	28
Potent α-glucosidase inhibitory activity of inoscavin A from fruiting bodies of Fulvifomes fastuosus: Mechanism of action, molecular docking and ADMET	28
Screening of small molecule compounds targeting hnRNPA2 protein	28
Pyrrolo[2,1-f][1,2,4]triazine: a promising fused heterocycle to target kinases in cancer therapy	27

Medicinal uses, phytochemistry, pharmacology, and taxonomy of Poygonum aviculare L.: a comprehensive review	25
Inhibition of protein kinases by proton pump inhibitors: computational screening and in vitro evaluation	25