OOIR: Observatory of International Research

Papers

(The H4-Index of Medicinal Chemistry Research is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Synthesis, characterization and in vitro antitumor activity of asiatic acid derivatives	118
Potent α-glucosidase inhibitory activity of inoscavin A from fruiting bodies of Fulvifomes fastuosus: Mechanism of action, molecular docking and ADMET	103
Targeting cAMP signaling and phosphodiesterase 4 for liver disease treatment	88
Synthesis and antitumor activity evaluation in vitro of 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole	77
Computer-aided design, synthesis and evaluation of new SARS-CoV-2 Mpro inhibitors based on 1,5,6,7-tetrahydro-4H-indazol-4-one scaffold	66
Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent	61
Design, synthesis, and antitumor activity evaluation of carbazole derivatives with potent HDAC inhibitory activity	58
Carbamoyl flavonoids as dual inhibitors of acetylcholinesterase and monoacylglycerol lipase: synthesis, in vitro evaluation, and computational studies	53
Evaluation of a series of nucleoside analogs as effective anticoronaviral-2 drugs against the Omicron-B.1.1.529/BA.2 subvariant: A repurposing research study	50
Antibacterial, antifungal activities and toxicity of new synthetic fatty acid salicylate esters	50
Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic antic	45
Asciminib: first FDA approved allosteric inhibitor of BCR-ABL1 for the treatment of chronic myeloid leukemia	43
Synthesis of the dibenzylbutane lignan LCA derivatives and evaluation of their anti-inflammatory activities	38
Synthesis of berberine derivatives and their antiviral activity toward respiratory syncytial virus	37
Anticancer activity of amide and ester derivatives of the ent-labdane 2α-hydroxyeperuic acid obtained via sonochemical synthesis	37
Monoamine oxidase inhibition by thiazole derivatives substituted with the benzenesulfonamide moiety	35
Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids	35
Novel imino-thiazoloquinoxaline derivatives against renal cell carcinoma: less radiation-damaging approach	35
Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal m	34
Glutathione and glutathione disulfide – their biomedical and pharmaceutical applications	34
Synthesis of tetrahydro-β-carboline analogs with N11 modifications and study of their antimalarial activities	33
Screening of small molecule compounds targeting hnRNPA2 protein	33
Design and synthesis of diphenyl-1H-imidazole analogs targeting Mpro/3CLpro enzyme of SARS-CoV-2	32
Plant-derived pyroptosis inducers as a therapeutic strategy in drug-resistant cancers	30
Contrasting effect of different crowding agents on pseudoknot RNA stability	30

Utilizing mechanistic organic chemistry training to study drug metabolism in preclinical drug discovery/development	29
Evaluation of benzoylacetonitriles as novel anti-neuroinflammatory agents	29
A versatile strategy for the synthesis of various lumazine peptides	29