OOIR: Observatory of International Research

Papers

(The median citation count of Reviews in Medical Virology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Correction to “Relative Efficacy, Effectiveness and Safety of Newer And/Or Enhanced Seasonal Influenza Vaccines for the Prevention of Laboratory‐Confirmed Influenza in Individuals Aged 18 Years and Ov	407
SARS‐CoV‐2 in digital era: Diagnostic techniques and importance of nucleic acid quantification with digital PCRs	274
Role of Gut Microbiota in Dengue	153
Hospitalised Dengue Patients and Risk of Hypertension: A Systematic Review and Meta‐Analysis	120
Human Metapneumovirus: A Review of Its Epidemiology, Clinical Features, Public Health Implications and Treatment Options	86
Clinical performance of rapid antigen tests in comparison to RT‐PCR for SARS‐COV‐2 diagnosis in Omicron variant: A systematic review and meta‐analysis	84
	82
COVID‐19 in hematopoietic stem‐cell transplant recipients: A systematic review and meta‐analysis of clinical characteristics and outcomes	68
Duration of protective immunity following COVID‐19 vaccination of individuals with underlying health conditions: A rapid review	66
Risk of kidney and liver diseases after COVID‐19 infection: A systematic review and meta‐analysis	64
Insight into the Enterovirus A71: A review	62
	61
	58
Norovirus outbreaks in China, 2000–2018: A systematic review	52
Maintaining an international response to zoonoses	50
Cover Image	49
Epidemiology, biosafety, and biosecurity of Avian Influenza: Insights from the East Mediterranean region	45
Test accuracy of rapid diagnostic tests and reverse‐transcription polymerase chain reaction against virus isolation in cell culture for assessing SARS‐CoV‐2 infectivity: Systematic review and meta‐ana	45
The Association Between Male Viral Infections and Infertility: A Systematic Review and Meta‐Analysis	44
Virus‐Induced Host Chemokine CCL2 in COVID‐19 Pathogenesis: Potential Prognostic Marker and Target of Anti‐Inflammatory Strategy	42
The role of cytokines and their antagonists in the treatment of COVID‐19 patients	40
Humoral immune response to two doses of COVID‐19 mRNA‐based vaccines in people living with HIV: A systematic review and meta‐analysis	40
Next Generation RNA/Protein‐Carrying Vector With Pleiotropic Activity	40
	39
Commentary on ‘Confounding Variable in Recent Clinical Trial on ORFV‐Based Therapeutics’	39

Efficacy and safety of long‐acting cabotegravir versus oral tenofovir disoproxil fumarate‐emtricitabine as HIV pre‐exposure prophylaxis: A systematic review and meta‐analysis	37
The programed death‐1/programed death ligand‐1 axis and its potential as a therapeutic target for virus‐associated tumours	36
Electroencephalographic findings post‐COVID‐19 vaccination: A systematic review of case reports and case series	33
Role of Neurotropic Viruses in Brain Metastasis of Breast Cancer: Mechanisms and Therapeutic Implications	33
Azvudine versus Paxlovid in COVID‐19: A systematic review and meta‐analysis	33
Issue Information	32
Aedes mosquitoes in the emerging threat of urban yellow fever transmission	32
Cell death mechanisms involved in cell injury caused by SARS‐CoV‐2	31
Potential intestinal infection and faecal‐oral transmission of human coronaviruses	31
Laboratory‐based testing for hepatitis C infection using dried blood spot samples: A systematic review and meta‐analysis of diagnostic accuracy	31
An annoying enteric virus: A systematic review and meta‐analysis of human astroviruses and gastrointestinal complications in children	30
Antioxidant/anti‐inflammatory effect of Mg²⁺ in coronavirus disease 2019 (COVID‐19)	30
Long‐term side effects and lingering symptoms post COVID‐19 recovery	30
Global molecular prevalence and genotype distribution of Sapovirus in children with gastrointestinal complications: A systematic review and meta‐analysis	29
Crosstalk between RNA viruses and DNA sensors: Role of the cGAS‐STING signalling pathway	29
	29
Reactivation of herpesviruses during COVID‐19: A systematic review and meta‐analysis	28
Impact of differentiated service delivery models on retention in HIV care and viral suppression among people living with HIV in sub‐Saharan Africa: A systematic review and meta‐analysis of randomised	27
Potential therapeutic strategies to halt viral neuroinvasion	27
Effect of prior immunisation with smallpox vaccine for protection against human Mpox: A systematic review	26
Megakaryopoiesis Dysregulation, Thrombocytopaenia, and Dengue Virus Pathogenesis: Molecular Mechanisms and Therapeutic Advances	26
Systematic review of host genetic association with Covid‐19 prognosis and susceptibility: What have we learned in 2020?	25
Effect of Comorbidities on the Mortality of Patients With COVID‐19: A Systematic Review of Reviews and Meta‐Analyses	25
Systematic review of the efficacy, effectiveness and safety of cell‐based seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of age	25
Neurological manifestations of Flaviviridae, Togaviridae, and Peribunyaviridae as vector‐borne viruses	25
Issue Information	24
Revisiting H7N9 Case Fatality Rate and Pathogenicity of Non‐H5/H7 Avian Influenza Viruses	24
Does dengue and COVID‐19 co‐infection have worse outcomes? A systematic review of current evidence	24
Tick‐borne encephalitis: A comprehensive review of the epidemiology, virology, and clinical picture	22
Sex affects immune response capacity against COVID‐19 infection	22
Safety and immunogenicity of Zika virus vaccine: A systematic review of clinical trials	22
Long non‐coding RNAs in virus‐related cancers	21
Cumulative incidence and mortality rate of cardiovascular complications due to laboratory‐confirmed influenza virus infection: A systematic review and meta‐analysis	21
The role of IL‐1β during human immunodeficiency virus type 1 infection	21
mTOR Signalling in Arbovirus Infections: Molecular Mechanisms and Therapeutic Opportunities	20
Increased risk of new‐onset cardiovascular disease after COVID‐19: A systematic review and meta‐analysis of 14 cohorts	20
Dengue Virus Life Cycle and Host Protein Interactions: Focus on RNA Binding Proteins and Therapeutic Advances	20
	20
Novel Human Polyomaviruses Discovered From 2007 to the Present: An Update of Current Knowledge	20
Strongyloides coinfection in COVID‐19 patients treated with corticosteroids: A systematic review	19
Comment on COVID‐19 vaccination during pregnancy, COVID and maternal and neonatal outcomes	19
Passive immunotherapies for the next influenza pandemic	18
Prevalence and outcomes of upper gastrointestinal bleeding in COVID‐19: A systematic review and meta‐analysis	18
Evaluating fluvoxamine for the outpatient treatment of COVID‐19: A systematic review and meta‐analysis	18
Clinical Manifestation of Arboviruses in Paediatrics	17
Crosstalk Between Innate Immunity and Autophagy in Viral Myocarditis Leading to Dilated Cardiomyopathy	17
An Overview on Disease Burden and Management of Respiratory Syncytial Virus Infections in Older Adults in the Asia‐Pacific Region	17
The Impact of HIV Upon the PCI Results: A Systematic Review and Meta‐Analysis	17
Nuclear factor erythroid 2‐related factor 2 in human papillomavirus‐related cancers	16
Cover Image	16

Issue Information	16
Caution should be exercised when assessing ivermectin for the treatment of COVID‐19 in systematic reviews	16
Prospects for developing an Hepatitis C virus E1E2‐based nanoparticle vaccine	16
Issue Information	16
Ethnicity as a risk factor for vitamin D deficiency and undesirable COVID‐19 outcomes	16
Molecular Evolution of the H5 and H7 Highly Pathogenic Avian Influenza Virus Haemagglutinin Cleavage Site Motif	15
The 2022 monkeypox outbreak 1 year on: The 5 Ws	15
Comprehensive adjusted outcome data are needed to assess the impact of immune checkpoint inhibitors in cancer patients with COVID‐19: Results of a systematic review and meta‐analysis	15
Neuroinflammation in Post COVID‐19 Sequelae: Neuroinvasion and Neuroimmune Crosstalk	15
Host and viral non‐coding RNAs in dengue pathogenesis	15
Immune Evasion Mechanism of Neurotropic Viruses	15
Systematic review of the efficacy, effectiveness and safety of MF59^® adjuvanted seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of	15
Seroprevalence of Viral Hepatitis B and Occult Hepatitis B Among Blood Donors in Africa: A Systematic Review and Meta‐Analysis	14
Interleukin‐6 inhibitory effect of natural product naringenin compared to a synthesised monoclonal antibody against life‐threatening COVID‐19	13
Modulation of various host cellular machinery during COVID‐19 infection	13
Issue Information	13
Nutritional Status as a Key Consideration in Dengue Vaccine Outcomes for Adolescents	13
Transmission and clearance of human papillomavirus infection in the oral cavity and its role in oropharyngeal carcinoma – A review	13
Role of Angiotensin II in Venezuelan Equine Encephalitis: Narrative Review	13
Estimating the key outcomes and hepatocellular carcinoma risk in patients in immune‐tolerant phase of chronic hepatitis B virus infection: A systematic review and meta‐analysis	13
The relationship between chikungunya virus and the kidneys: A scoping review	13
Diagnostic performance of hepatitis C core antigen assay to identify active infections: A systematic review and meta‐analysis	13
Serum ferritin level as a prognostic biomarker for predicting dengue disease severity: A systematic review and meta‐analysis	13
Role of the VEGF in virus‐associated cancers	13
Sphingosine‐1‐phosphate related signalling pathways manipulating virus replication	13
	12
Cardiac complications following mRNA COVID‐19 vaccines: A systematic review of case reports and case series	12
Laboratory biomarkers and prognosis in Covid‐19, where do we stand?	12
Targeting the mammalian target of rapamycin pathway in neurological manifestations of Covid‐19	12
Autoantibodies in COVID‐19 and Other Viral Diseases: Molecular, Cellular, and Clinical Perspectives	11
Virus‐induced host cell metabolic alteration	11
Prevalence of oral manifestations in COVID‐19: A systematic review	11
Hepatitis A in Latin America: The current scenario	11
Canonical fibroblast growth factors in viral infection	11
The Potential Role of Zika and Dengue Virus Infection in the Urogenital System Disorders: An Overview	11
Targeting epidermal growth factor receptor signalling pathway: A promising therapeutic option for COVID‐19	11
	11
Mechanisms of Immune Evasion of West Nile Virus	10
Issue Information	10
The concept of one health applied to the problem of zoonotic diseases	10
Hospitalised versus outpatient COVID‐19 patients' background characteristics and comorbidities: A systematic review and meta‐analysis	10
Protective and pathological roles of regulatory immune cells in human cytomegalovirus infection following hematopoietic stem cell transplantation	10
	10
Hepatitis B virus core‐related antigen (HBcrAg) as a prognostic marker for the development of hepatocellular carcinoma: A mini systematic review of the literature	10
Omicron – The new SARS‐CoV‐2 challenge?	10
Systematic review of the efficacy, effectiveness and safety of recombinant haemagglutinin seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of a	10
Zika Virus‐Related Birth Defects and Neurological Complications: A Systematic Review and Meta‐Analysis	9
Biomarker based biosensors: An opportunity for diagnosis of COVID‐19	9
Comparable performance of antigen‐detecting rapid test by healthcare worker‐collected and self‐collected swabs for SARS‐CoV‐2 diagnostic: A systematic review and meta‐analysis	9
Regulatory role of miRNAs in the human immune and inflammatory response during the infection of SARS‐CoV‐2 and other respiratory viruses: A comprehensive review	9
Issue Information	9
Nuclear Factor of Activated T Cells Signalling and Viral Pathogens: A Dynamic Cross‐Talk	9
Haemagglutinin, neuraminidase and haemagglutinin esterase on the surface of SARS‐CoV‐2?	9
Genomic and biological variation in bat IFNs: An antiviral treatment approach	9
Immunoinformatics applications in the development of therapeutic vaccines against human papillomavirus‐related infections and cervical cancer	9
Great expectations: Living with and not dying from Covid‐19	9
Effect of corticosteroid therapy on mortality in COVID‐19 patients—A systematic review and meta‐analysis	9
Varicella‐zoster virus‐related neurological complications: From infection to immunomodulatory therapies	9
An overview of SARS‐CoV2 natural infections in companion animals: A systematic review of the current evidence	9
Issue Information	9
SARS‐CoV‐2, periodontal pathogens, and host factors: The trinity of oral post‐acute sequelae of COVID‐19	8
Epstein‐Barr virus regulates the life cycle and host cell biology by hijacking post‐translational modification	8
Histomolecular characterisation of hepatitis B virus induced liver cancer	8
Dengue Infection During Pregnancy and Adverse Birth Outcomes: A Systematic Review and Meta‐Analysis	8
Relative Efficacy, Effectiveness and Safety of Newer and/or Enhanced Seasonal Influenza Vaccines for the Prevention of Laboratory‐Confirmed Influenza in Individuals Aged 18 years and Over: Update of a	8
Higher body temperatures associated with immunotherapy may affect the activity of therapeutic antibodies	8
Clinical efficacy and effectiveness of alternative varicella vaccination strategies: An overview of reviews	8
Zika and Dengue Virus Autoimmunity: An Overview of Related Disorders and Their Potential Mechanisms	8
Efficacy and safety of paxlovid (nirmatrelvir/ritonavir) in the treatment of COVID‐19: An updated meta‐analysis and trial sequential analysis	8
Unravelling the triad of neuroinvasion, neurodissemination, and neuroinflammation of human immunodeficiency virus type 1 in the central nervous system	8
Issue Information	7
Infectious viruses and neurodegenerative diseases: The mitochondrial defect hypothesis	7
Rodent‐borne viruses in the region of Middle East	7
Effectiveness of rapid antigen testing for screening of asymptomatic individuals to limit the transmission of SARS‐CoV‐2: A rapid review	7
Treatment Efficacy in Herpes Zoster Ophthalmoplegia: A Systematic Review and Meta‐Analysis of Case Reports and Series	7
Ferritin: Significance in viral infections	7
Systematic Review of the Efficacy and Safety of RSV‐Specific Monoclonal Antibodies and Antivirals in Development	7
Blood‐borne viruses and neurological manifestations: An overview	7
A comparison with historical influenza prompts better planning for Covid‐19 and future pandemics, and gives grounds for optimism	7
	7

Pharmacological advances in anti‐retroviral therapy for human immunodeficiency virus‐1 infection: A comprehensive review	7
Neurological Implications of Poxvirus Infections: Pathogenesis, Neurotropism, and Clinical Manifestations	7
Safety and potency of BIV1‐CovIran inactivated vaccine candidate for SARS‐CoV‐2: A preclinical study	7
The knowns and unknowns of cardiac autoimmunity in viral myocarditis	6
EBV associated T‐ and NK‐cell lymphoproliferative diseases: A comprehensive overview of clinical manifestations and novel therapeutic insights	6
Monkeypox virus diagnosis and laboratory testing	6
Efficacy of tocilizumab in the treatment of COVID‐19: An umbrella review	6
Hijacking and rewiring of host CircRNA/miRNA/mRNA competitive endogenous RNA (ceRNA) regulatory networks by oncoviruses during development of viral cancers	6
Muscle dysfunction in the long coronavirus disease 2019 syndrome: Pathogenesis and clinical approach	6
Anakinra was not associated with lower mortality in hospitalised COVID‐19 patients: A systematic review and meta‐analysis of randomized controlled trials	6
Regulation of miRNA in Cytokine Storm (CS) of COVID‐19 and Other Viral Infection: An Exhaustive Review	6
Virus infection participates in the occurrence and development of human diseases through monoamine oxidase	6
Assessing severe acute respiratory syndrome coronavirus 2 infectivity by reverse‐transcription polymerase chain reaction: A systematic review and meta‐analysis	6
Differentially‐regulated miRNAs in COVID‐19: A systematic review	6
Update on the omicron sub‐variants BA.4 and BA.5	6
Genetics, structure, transmission, epidemiology, immune response, and vaccine efficacies of the SARS‐CoV‐2 Delta variant: A comprehensive review	6
Monitoring Macrophage Polarization in Infectious Disease, Lesson From SARS‐CoV‐2 Infection	6
What are the neurodevelopmental outcomes of children with asymptomatic congenital cytomegalovirus infection at birth? A systematic literature review	6
Baseline physical activity is associated with reduced mortality and disease outcomes in COVID‐19: A systematic review and meta‐analysis	6
Targeting EBV‐encoded products: Implications for drug development in EBV‐associated diseases	5
Merkel Cell Polyomavirus—Pathophysiology and Treatment in the Era of Gene‐Targeted Therapies	5
Effects of COVID‐19 vaccination during pregnancy on SARS‐CoV‐2 infection and maternal and neonatal outcomes: A systematic review and meta‐analysis	5
Parechovirus A infection and risk of gastroenteritis in children: A systematic review and meta‐analysis	5
Combating coxsackievirus B infections	5
The association between various viral infections and multiple sclerosis: An umbrella review on systematic review and meta‐analysis	5
Voltage‐dependent anion channels: Key players in viral infection	5
Clinical manifestations of dengue, Zika and chikungunya in the Pacific Islands: A systematic review and meta‐analysis	5
Potential relationship between cytomegalovirus and immunosenescence: Evidence from observational studies	5
Issue Information	5
Prognostic value of novel serum biomarkers, including C‐reactive protein to albumin ratio and fibrinogen to albumin ratio, in COVID‐19 disease: A meta‐analysis	5
Human bocavirus respiratory infection: Tracing the path from viral replication and virus‐cell interactions to diagnostic methods	5
Immunopathology of herpes simplex virus‐associated neuroinflammation: Unveiling the mysteries	5
Human immunodeficiency virus infection challenges: Current therapeutic limitations and strategies for improved management through long‐acting injectable formulation	5
Oral Manifestations in the Post COVID‐19 Condition: A Systematic Review With Meta‐Analysis	5
Human adenovirus type 26 basic biology and its usage as vaccine vector	5
The impact of COVID 19 on the outcomes of thrombectomy in stroke patients: A systematic review and meta‐analysis	5
The Correlation of Arboviruses With the Risk of Diabetes Mellitus: A Systematic Review and Meta‐Analysis of Current Evidence	4
SARS‐CoV‐2 Omicron and its current known unknowns: A narrative review	4
Serological response and immune‐related adverse events following COVID‐19 vaccination in cancer patients treated with immune checkpoint inhibitors: A systematic review and meta‐analysis	4
A Systematic Review of BK and JC Polyomaviruses in Asia: Molecular Insights and Prevalence	4
Issue Information	4
Intravenous immunoglobulin (IVIg) therapy in hospitalised adult COVID‐19 patients: A systematic review and meta‐analysis	4
A comprehensive review of Langya virus and framework for future zoonotic disease control	4
	4
Emerging Nipah Virus With Pandemic Potential and High Mortality Rates: Is the Scientific Community Learning From Former Pandemics?	4
The relationship between HIV‐1 neuroinflammation, neurocognitive impairment and encephalitis pathology: A systematic review of studies investigating post‐mortem brain tissue	4
The impact of trained immunity in respiratory viral infections	4
Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection	4
Cell Biology of Human Cytomegalovirus Latency: Implications for Pathogenesis and Treatment	4
Issue Information	4
Utilising biosensor‐based approaches for identifying neurotropic viruses	4
	4
Cerebrospinal fluid viral escape in HIV patients on antiretroviral therapy: A systematic review of reported cases	4
The controversy of SARS‐CoV‐2 integration into the human genome	4
Advancing ORFV‐Based Therapeutics to the Clinical Stage	4
Reemergence of Marburgvirus disease: Update on current control and prevention measures and review of the literature	4
	4
Alzheimer's disease and herpes viruses: Current events and perspectives	4
Worldwide prevalence of human papillomavirus among pregnant women: A systematic review and meta‐analysis	4