OOIR: Observatory of International Research

Papers

(The median citation count of Reviews in Medical Virology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Evolution of the SARS‐CoV‐2 omicron variants BA.1 to BA.5: Implications for immune escape and transmission	332
Covid‐19 vaccines and variants of concern: A review	218
Clinical characteristics and outcomes of pregnant women with COVID‐19 and comparison with control patients: A systematic review and meta‐analysis	173
Neutralising antibody escape of SARS‐CoV‐2 spike protein: Risk assessment for antibody‐based Covid‐19 therapeutics and vaccines	135
An overview on the seven pathogenic human coronaviruses	109
Loop‐mediated isothermal amplification (LAMP): An effective molecular point‐of‐care technique for the rapid diagnosis of coronavirus SARS‐CoV‐2	103
Proposed subtypes of post‐COVID‐19 syndrome (or long‐COVID) and their respective potential therapies	91
Sex‐based differences in severity and mortality in COVID‐19	87
Present variants of concern and variants of interest of severe acute respiratory syndrome coronavirus 2: Their significant mutations in S‐glycoprotein, infectivity, re‐infectivity, immune escape and v	73
Cardiac complications following mRNA COVID‐19 vaccines: A systematic review of case reports and case series	69
Covid‐19 and oral diseases: Crosstalk, synergy or association?	64
Global prevalence and genotype distribution of norovirus infection in children with gastroenteritis: A meta‐analysis on 6 years of research from 2015 to 2020	61
Quantifying the risk of SARS‐CoV‐2 reinfection over time	58
How artificial intelligence may help the Covid‐19 pandemic: Pitfalls and lessons for the future	58
Diagnostic accuracy of serological tests and kinetics of severe acute respiratory syndrome coronavirus 2 antibody: A systematic review and meta‐analysis	57
Potential detrimental role of soluble ACE2 in severe COVID‐19 comorbid patients	56
Influenza vaccines: Past, present, and future	54
Immunity and inflammatory biomarkers in COVID‐19: A systematic review	53
Potency of BNT162b2 and mRNA‐1273 vaccine‐induced neutralizing antibodies against severe acute respiratory syndrome‐CoV‐2 variants of concern: A systematic review of in vitro studies	52
Inflammatory and vascular biomarkers in post‐COVID‐19 syndrome: A systematic review and meta‐analysis of over 20 biomarkers	51
Respiratory viral co‐infections in patients with COVID‐19 and associated outcomes: A systematic review and meta‐analysis	50
Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID‐19 patients: A systematic review and meta‐analysis	50
Update on the omicron sub‐variants BA.4 and BA.5	49
Genetic polymorphisms of ACE1, ACE2, and TMPRSS2 associated with COVID‐19 severity: A systematic review with meta‐analysis	48
Seroprevalence of anti‐SARS‐CoV‐2 antibodies in Africa: A systematic review and meta‐analysis	48

C‐reactive protein as an effector molecule in Covid‐19 pathogenesis	47
Oral manifestations of Covid‐19‐A literature review	46
Global and regional circulation trends of norovirus genotypes and recombinants, 1995–2019: A comprehensive review of sequences from public databases	42
Classical and alternative receptors for SARS‐CoV‐2 therapeutic strategy	42
Long‐term side effects and lingering symptoms post COVID‐19 recovery	42
Altered gut microbial metabolites could mediate the effects of risk factors in Covid‐19	41
A systematic meta‐analysis of immune signatures in patients with COVID‐19	39
Baseline physical activity is associated with reduced mortality and disease outcomes in COVID‐19: A systematic review and meta‐analysis	36
ASSURED‐compliant point‐of‐care diagnostics for the detection of human viral infections	36
Mesenchymal stem cells and their derived exosomes to combat Covid–19	34
Recent insights into SARS‐CoV‐2 omicron variant	34
Rhinovirus and asthma: Challenges and opportunities	34
Role of p38 mitogen‐activated protein kinase signalling in virus replication and potential for developing broad spectrum antiviral drugs	34
The concept of one health applied to the problem of zoonotic diseases	33
SARS‐CoV‐2, Covid‐19, and the debunking of conspiracy theories	32
A systematic review on global RSV genetic data: Identification of knowledge gaps	31
Comparative effectiveness of N95, surgical or medical, and non‐medical facemasks in protection against respiratory virus infection: A systematic review and network meta‐analysis	31
Efficacy and safety of azithromycin in Covid‐19 patients: A systematic review and meta‐analysis of randomized clinical trials	30
Omicron – The new SARS‐CoV‐2 challenge?	30
Reactivation of herpesviruses during COVID‐19: A systematic review and meta‐analysis	29
Epidemiology, prognosis and management of potassium disorders in Covid‐19	28
Population‐based prevalence surveys during the Covid‐19 pandemic: A systematic review	28
Role of red blood cell distribution width, as a prognostic indicator in COVID‐19: A systematic review and meta‐analysis	28
Safety and potency of BIV1‐CovIran inactivated vaccine candidate for SARS‐CoV‐2: A preclinical study	27
SARS‐CoV‐2 Omicron and its current known unknowns: A narrative review	27
Effect of rotavirus genetic diversity on vaccine impact	27
Monkeypox virus diagnosis and laboratory testing	27
Muscle dysfunction in the long coronavirus disease 2019 syndrome: Pathogenesis and clinical approach	27
Vaccine‐induced immune thrombotic thrombocytopenia after vaccination against Covid‐19: A clinical dilemma for clinicians and patients	27
Impact of COVID‐19 on polio vaccination in Pakistan: a concise overview	26
Dengue fever and dengue virus in the People's Republic of China	26
Effects of COVID‐19 vaccination during pregnancy on SARS‐CoV‐2 infection and maternal and neonatal outcomes: A systematic review and meta‐analysis	26
Reactive oxygen species as potential antiviral targets	25
Vitamin D supplementation and Covid‐19 outcomes: A systematic review, meta‐analysis and meta‐regression	25
Neurological complications associated with Covid‐19; molecular mechanisms and therapeutic approaches	25
Torque teno virus load as marker of rejection and infection in solid organ transplantation – A systematic review and meta‐analysis	25
Epidemiology of human adenovirus associated with respiratory infection in southern Brazil	25
Nanobiosensor‐based diagnostic tools in viral infections: Special emphasis on Covid‐19	24
Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection	24
Efficacy and safety of sotrovimab in patients with COVID‐19: A rapid review and meta‐analysis	24
The impact of Parkinson's disease on manifestations and outcomes of Covid‐19 patients: A systematic review and meta‐analysis	24
Lipid‐based therapies against SARS‐CoV‐2 infection	24
Prognostic value of novel serum biomarkers, including C‐reactive protein to albumin ratio and fibrinogen to albumin ratio, in COVID‐19 disease: A meta‐analysis	23
The effects of orally administered lactoferrin in the prevention and management of viral infections: A systematic review	23
Efficacy and safety of tixagevimab‐cilgavimab as pre‐exposure prophylaxis for COVID‐19: A systematic review and meta‐analysis	23
Mega doses of retinol: A possible immunomodulation in Covid‐19 illness in resource‐limited settings	23
Zoonotic potential of Newcastle disease virus: Old and novel perspectives related to public health	23
Crosstalk between RNA viruses and DNA sensors: Role of the cGAS‐STING signalling pathway	22
Clinical manifestations of human Mpox infection: A systematic review and meta‐analysis	22
Prevalence and genotype distribution of human papillomavirus infection in different anatomical sites among men who have sex with men: A systematic review and meta‐analysis	21

Transmission and clearance of human papillomavirus infection in the oral cavity and its role in oropharyngeal carcinoma – A review	21
Severe acute respiratory syndrome coronavirus‐2 natural animal reservoirs and experimental models: systematic review	20
Coronavirus disease 2019 (Covid‐19) vaccination recommendations in special populations and patients with existing comorbidities	20
Monkeypox: An international epidemic	20
Recent developments in SARS‐CoV‐2 vaccines: A systematic review of the current studies	20
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS‐CoV‐2 susceptibility and the drug‐metabolising genes used in treatment	19
SARS‐CoV‐2 and dengue virus co‐infection: Epidemiology, pathogenesis, diagnosis, treatment, and management	19
Insight into the Enterovirus A71: A review	19
The global emergence of Chikungunya infection: An integrated view	19
Cell death mechanisms involved in cell injury caused by SARS‐CoV‐2	19
Prevalence of oral manifestations in COVID‐19: A systematic review	19
Norovirus outbreaks in China, 2000–2018: A systematic review	19
Effect of prior immunisation with smallpox vaccine for protection against human Mpox: A systematic review	18
EBV associated T‐ and NK‐cell lymphoproliferative diseases: A comprehensive overview of clinical manifestations and novel therapeutic insights	18
Diverse roles of long non‐coding RNAs in viral diseases	18
Ivermectin and outcomes from Covid‐19 pneumonia: A systematic review and meta‐analysis of randomized clinical trial studies	17
The virome in early life and childhood and development of islet autoimmunity and type 1 diabetes: A systematic review and meta‐analysis of observational studies	17
Innate immune evasion mediated by picornaviral 3C protease: Possible lessons for coronaviral 3C‐like protease?	17
Development of antibody resistance in emerging mutant strains of SARS CoV‐2: Impediment for COVID‐19 vaccines	17
Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; An updated review	17
Systematic review of the efficacy, effectiveness and safety of high‐dose seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of age	16
Hospitalised versus outpatient COVID‐19 patients' background characteristics and comorbidities: A systematic review and meta‐analysis	16
Clinical performance of rapid antigen tests in comparison to RT‐PCR for SARS‐COV‐2 diagnosis in Omicron variant: A systematic review and meta‐analysis	15
Aedes mosquitoes in the emerging threat of urban yellow fever transmission	15
Effect of corticosteroid therapy on mortality in COVID‐19 patients—A systematic review and meta‐analysis	15
Current views on the potentials of convalescent plasma therapy (CPT) as Coronavirus disease 2019 (COVID‐19) treatment: A systematic review and meta‐analysis based on recent studies and previous respir	15
Quercetin for the treatment of COVID‐19 patients: A systematic review and meta‐analysis	15
Intravenous immunoglobulin (IVIg) therapy in hospitalised adult COVID‐19 patients: A systematic review and meta‐analysis	15
Effectiveness of public health measures to prevent the transmission of SARS‐CoV‐2 at mass gatherings: A rapid review	15
Detection of respiratory viruses directly from clinical samples using next‐generation sequencing: A literature review of recent advances and potential for routine clinical use	14
The relationship between blood groups and risk of infection with SARS‐CoV‐2 or development of severe outcomes: A review	14
HTLV‐1 oncovirus‐host interactions: From entry to the manifestation of associated diseases	14
Redox‐sensitive signalling pathways regulated by human papillomavirus in HPV‐related cancers	14
The association of human leucocyte antigen (HLA) alleles with COVID‐19 severity: A systematic review and meta‐analysis	14
Clinical and laboratory factors associated with coronavirus disease 2019 (Covid‐19): A systematic review and meta‐analysis	13
Long noncoding RNAs in respiratory viruses: A review	13
Safety and immunogenicity of Zika virus vaccine: A systematic review of clinical trials	13
The Suppressor of Cytokine Signalling family of proteins and their potential impact on COVID‐19 disease progression	13
Passive immunotherapies for COVID‐19: The subtle line between standard and hyperimmune immunoglobulins is getting invisible	13
Association of adenovirus 36 infection and obesity; An updated meta‐analysis of community‐based studies	13
Isothermal amplification‐based assays for rapid and sensitive detection of severe acute respiratory syndrome coronavirus 2: Opportunities and recent developments	13
Temperature dependent viral tropism: understanding viral seasonality and pathogenicity as applied to the avoidance and treatment of endemic viral respiratory illnesses	13
Behaviour of aerosols and their role in the transmission of SARS‐CoV‐2; a scoping review	13
Worldwide prevalence of human papillomavirus among pregnant women: A systematic review and meta‐analysis	13
Combating coxsackievirus B infections	12
Type B coxsackieviruses and central nervous system disorders: critical review of reported associations	12
Model systems for studying extrahepatic pathogenesis of hepatitis E virus. Current knowledge and future directions	12
Interindividual immunogenic variants: Susceptibility to coronavirus, respiratory syncytial virus and influenza virus	12
Systematic review of the efficacy, effectiveness and safety of cell‐based seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of age	12
The prevalence, predictors and outcomes of acute liver injury among patients with COVID‐19: A systematic review and meta‐analysis	12
Assessing severe acute respiratory syndrome coronavirus 2 infectivity by reverse‐transcription polymerase chain reaction: A systematic review and meta‐analysis	12
Does enterovirus 71 urge for effective vaccine control strategies? Challenges and current opinion	12
The role of IL‐1β during human immunodeficiency virus type 1 infection	12
Human brain organoids to explore SARS‐CoV‐2‐induced effects on the central nervous system	12
Systematic review of host genetic association with Covid‐19 prognosis and susceptibility: What have we learned in 2020?	12
Antioxidant/anti‐inflammatory effect of Mg²⁺ in coronavirus disease 2019 (COVID‐19)	12
Efficacy and safety of paxlovid (nirmatrelvir/ritonavir) in the treatment of COVID‐19: An updated meta‐analysis and trial sequential analysis	12
Persistence of humoral response upon SARS‐CoV‐2 infection	12
Does dengue and COVID‐19 co‐infection have worse outcomes? A systematic review of current evidence	11
The effectiveness of non‐contact thermal screening as a means of identifying cases of Covid‐19: a rapid review of the evidence	11
Tick‐borne encephalitis: A comprehensive review of the epidemiology, virology, and clinical picture	10
Metabolic reprogramming and immune regulation in viral diseases	10
Insights on Mpox virus infection immunopathogenesis	10
SARS‐CoV‐2 nucleocapsid: Biological functions and implication for disease diagnosis and vaccine design	10
Hepatitis B virus core‐related antigen (HBcrAg) as a prognostic marker for the development of hepatocellular carcinoma: A mini systematic review of the literature	10
An annoying enteric virus: A systematic review and meta‐analysis of human astroviruses and gastrointestinal complications in children	10
The role of cytokines and their antagonists in the treatment of COVID‐19 patients	10
Crosstalk between estrogen, dendritic cells, and SARS‐CoV‐2 infection	10
Therapeutic roles of CAR T cells in infectious diseases: Clinical lessons learnt from cancer	10
Antivirals against human polyomaviruses: Leaving no stone unturned	10
Viruses of the oral cavity: Prevalence, pathobiology and association with oral diseases	9
A systematic review and meta‐analysis of the prevalence of human cytomegalovirus shedding in seropositive pregnant women	9
Indirect effects of cytomegalovirus infection: Implications for vaccine development	9
A rapid review of measures to support people in isolation or quarantine during the Covid‐19 pandemic and the effectiveness of such measures	9
Effectiveness of rapid antigen testing for screening of asymptomatic individuals to limit the transmission of SARS‐CoV‐2: A rapid review	9
Tocilizumab in COVID‐19 pneumonia: Practical proposals based on a narrative review of randomised trials	9
Global molecular prevalence and genotype distribution of Sapovirus in children with gastrointestinal complications: A systematic review and meta‐analysis	9
Biomarkers of endothelial dysfunction are associated with poor outcome in COVID‐19 patients: A systematic review and meta‐analysis	9
COVID‐19 susceptibility and clinical outcomes in inflammatory bowel disease: An updated systematic review and meta‐analysis	9
Review of studies of severe acute respiratory syndrome related coronavirus–2 pathogenesis in human organoid models	9

Background to new treatments for COVID‐19, including its chronicity, through altering elements of the cytokine storm	8
Host factors associated with either VP16 or VP16‐induced complex differentially affect HSV‐1 lytic infection	8
SARS‐CoV‐2‐related and Covid‐19 vaccine‐induced thromboembolic events: A comparative review	8
Differentially‐regulated miRNAs in COVID‐19: A systematic review	8
Virus‐like particles as powerful vaccination strategy against human viruses	8
Systematic review of the efficacy, effectiveness and safety of MF59^® adjuvanted seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of	8
Safety and efficacy of COVID‐19 vaccines: A systematic review and meta‐analysis of controlled and randomized clinical trials	8
Features of HLA class I expression and its clinical relevance in SARS‐CoV‐2: What do we know so far?	8
Risk profile and mode of transmission of Mpox: A rapid review and individual patient data meta‐analysis of case studies	8
COVID‐19 outcomes in paediatric cancer: A large scale pooled meta‐analysis of 984 cancer patients	8
Viral modulation of lipid rafts and their potential as putative antiviral targets	7
Rodent‐borne viruses in the region of Middle East	7
Ethnicity as a risk factor for vitamin D deficiency and undesirable COVID‐19 outcomes	7
Hepatitis B virus pre‐S region: Clinical implications and applications	7
Anakinra was not associated with lower mortality in hospitalised COVID‐19 patients: A systematic review and meta‐analysis of randomized controlled trials	7
Sphingosine‐1‐phosphate related signalling pathways manipulating virus replication	7
Epitope mapping of neutralising anti‐SARS‐CoV‐2 monoclonal antibodies: Implications for immunotherapy and vaccine design	7
Partners in crime: Autoantibodies complicit in COVID‐19 pathogenesis	7
How strong is the evidence that it is possible to get SARS‐CoV‐2 twice? A systematic review	7
Systematic review of the efficacy, effectiveness and safety of recombinant haemagglutinin seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals ≥18 years of a	7
Efficacy of tocilizumab in the treatment of COVID‐19: An umbrella review	7
Human pegivirus type 1 infection in Asia—A review of the literature	7
Hydroxychloroquine in the treatment of coronavirus disease 2019: Rapid updated systematic review and meta‐analysis	7
Cardiac manifestations in children with the multisystem inflammatory syndrome (MIS‐C) associated with SARS‐CoV‐2 infection: Systematic review and meta‐analysis	7
Testosterone and Covid‐19: An update	7
Human adenovirus type 26 basic biology and its usage as vaccine vector	6
Prospects for developing an Hepatitis C virus E1E2‐based nanoparticle vaccine	6
Biomarker based biosensors: An opportunity for diagnosis of COVID‐19	6
Complement inhibition: A possible therapeutic approach in the fight against Covid‐19	6
Host and viral non‐coding RNAs in dengue pathogenesis	6
Pharmacological interventions to prevent Covid‐19 disease: A rapid review	6
Nuclear factor erythroid 2‐related factor 2 in human papillomavirus‐related cancers	6
Respiratory infections and type 1 diabetes: Potential roles in pathogenesis	5
Laboratory‐based testing for hepatitis C infection using dried blood spot samples: A systematic review and meta‐analysis of diagnostic accuracy	5
Safety of varicella vaccination strategies: An overview of reviews	5
Proteomes, kinases and signalling pathways in virus‐induced filopodia, as potential antiviral therapeutics targets	5
Laboratory biomarkers and prognosis in Covid‐19, where do we stand?	5
Comprehensive adjusted outcome data are needed to assess the impact of immune checkpoint inhibitors in cancer patients with COVID‐19: Results of a systematic review and meta‐analysis	5
Global polio eradication; can we replicate the smallpox success story?	5
Recent advances to overcome the burden of Japanese encephalitis: A zoonotic infection with problematic early detection	5
Sex affects immune response capacity against COVID‐19 infection	5
The knowns and unknowns of cardiac autoimmunity in viral myocarditis	5
COVID‐19 in hematopoietic stem‐cell transplant recipients: A systematic review and meta‐analysis of clinical characteristics and outcomes	5
Evaluating fluvoxamine for the outpatient treatment of COVID‐19: A systematic review and meta‐analysis	5
Long non‐coding RNAs in virus‐related cancers	5
Clinical efficacy of anti‐SARS‐CoV‐2 monoclonal antibodies in preventing hospitalisation and mortality among patients infected with Omicron variants: A systematic review and meta‐analysis	4
Hepatitis E virus (HEV) open reading frame 2: Role in pathogenesis and diagnosis in HEV infections	4
Mitochondrial changes associated with viral infectious diseases in the paediatric population	4
Host genetic determinants of COVID‐19 susceptibility and severity: A systematic review and meta‐analysis	4
The impact of COVID 19 on the outcomes of thrombectomy in stroke patients: A systematic review and meta‐analysis	4
Dynamics of viral disease outbreaks: A hundred years (1918/19–2019/20) in retrospect ‐ Loses, lessons and emerging issues	4
Impact of differentiated service delivery models on retention in HIV care and viral suppression among people living with HIV in sub‐Saharan Africa: A systematic review and meta‐analysis of randomised	4
Tenofovir disoproxil fumarate for prevention of mother‐to‐child transmission of hepatitis B virus: A systematic review and meta‐analysis of randomised control trials	4
Is SARS‐CoV‐2 viral clearance in nasopharyngeal swabs an appropriate surrogate marker for clinical efficacy of neutralising antibody‐based therapeutics?	4
Cross talk between hepatitis B virus and innate immunity of hepatocytes	4
Reemergence of Marburgvirus disease: Update on current control and prevention measures and review of the literature	4
Parechovirus A infection and risk of gastroenteritis in children: A systematic review and meta‐analysis	4
Immunogenicity, clinical efficacy and safety of additional second COVID‐19 booster vaccines against Omicron and its subvariants: A systematic review	4
Clinical manifestations of dengue, Zika and chikungunya in the Pacific Islands: A systematic review and meta‐analysis	4
Biomarkers of transfusion transmitted occult hepatitis B virus infection: Where are we and what next?	4
Management of neonatal central nervous system viral infections: Knowledge gaps and research priorities	4
Salivirus infection: Systematic review and meta‐analysis of association with gastrointestinal symptoms in children	4
Recent developments on Junin virus, a causative agent for Argentine haemorrhagic fever	4
The relationship between HIV‐1 neuroinflammation, neurocognitive impairment and encephalitis pathology: A systematic review of studies investigating post‐mortem brain tissue	4
Voltage‐dependent anion channels: Key players in viral infection	4