OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Structural Biology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	46
Characterization of NMDA receptor Allostery modulation	42
Calcium carbonate deposition in the spicules of the sponge Heteropia glomerosa (Porifera, Calcarea)	39
Allosteric inhibition of cytosolic NADP+-dependent isocitrate dehydrogenase by oxaloacetate	38
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	38
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2	37
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	37
Keratin intermediate filament chains in the European common wall lizard (Podarcis muralis) and a potential keratin filament crosslinker	37
Disorder-to-order transition of Synaptobrevin-2: Tracing the conformational diversity of a synaptic SNARE protein	36
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	35
Inter-Domain interactions Slow BoNT/A’s onset of action	35
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	31
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	31
TomoAlign: A novel approach to correcting sample motion and 3D CTF in CryoET	31
Studying protein–protein interactions: Latest and most popular approaches	27
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	25
Multishot tomography for high-resolution in situ subtomogram averaging	25
Outside Front Cover	25
Isolation and reconstruction of cardiac mitochondria from SBEM images using a deep learning-based method	24
Interaction of berberine with different forms of DNA in human telomeric region	24
Outside Front Cover	23
It’s noisy out there! A review of denoising techniques in cryo-electron tomography	21
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	20
ArtiaX: geometric models, camera paths and image processing tools	20
Editorial Board	19

Structure and heterogeneity of a highly cargo-loaded encapsulin shell	19
JBP1 and JBP3 have conserved structures but different affinity to base-J	19
Insights into the pathogenic mechanisms associated with the SARS-CoV-2 spike protein	19
Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation	19
Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2	19
3D quantification of the lacunocanalicular network on human femoral diaphysis through synchrotron radiation-based nanoCT	18
Structural and dynamic insights into the HNH nuclease of divergent Cas9 species	17
Outside Front Cover	17
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region	17
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase	17
Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1	17
Crystal structure of the Escherichia coli CusS kinase core	17
Focused classifications and refinements in high-resolution single particle cryo-EM analysis	17
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography	16
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism	16
Nickel-NTA lipid-monolayer affinity grids allow for high-resolution structure determination by cryo-EM	16
Common structural features in some of the sequentially distant neurotransmitter transporters N-termini	15
Local defocus estimation in single particle analysis in cryo-electron microscopy	15
New insight on spatial localization and microstructures of calcite-aragonite interfaces in adult shell of Haliotis tuberculata: Investigations of wild and farmed abalones by FTIR and Raman mapping	15
Preferential binding as a driving mechanism of lipid domains formation	15
Daisy: An integrated repeat protein curation service	13
Three dimensional structures of the inner and outer pig petrous bone using FIB-SEM: Implications for development and ancient DNA preservation	13
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity	13
Outside Front Cover	13
Outside Front Cover	13
EMDA: A Python package for Electron Microscopy Data Analysis	13
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	13
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	12
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	11
Genetic basis of stony coral biomineralization: History, trends and future prospects	11
Cholesterol crystals in reservosomes of Trypanosoma cruzi	11
2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53	11
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	11
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	11
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	11
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	10
Structural analysis of the water channel AQP2 by single-particle cryo-EM	10
Outside Front Cover	10
Cell recognition based on atomic force microscopy and modified residual neural network	10
Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis	10
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	10
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor	9
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	9
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	9
Outside Front Cover	9
Opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging	9
Characterization of heterogeneity in nanodisc samples using Feret signatures	8
MEPSi: A tool for simulating tomograms of membrane-embedded proteins	8
Outside Front Cover	8
Structural insights into ring-building motif domains involved in bacterial sporulation	8

Dense intracellular ion pools in unicellular organisms	8
Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7	8
Journal of Structural Biology – Paper of the Year 2022	8
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	8
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	8
Outside Front Cover	8
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	8
Editorial Board	8
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	8
The role of tandem repeats in bacterial functional amyloids	7
Structure and self-association of Arrestin-1	7
Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography	7
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata	7
Insight into structural biophysics from solution X-ray scattering	7
3D distribution of biomineral and chitin matrix in the stomatopod dactyl club by high energy XRD-CT	7
Evolution and biomineralization of pteropod shells	7
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	7
The intricacies of tooth enamel: Embryonic origin, development and human genetics	7
Effects of Xylanase A double mutation on substrate specificity and structural dynamics	7
Mean curvature motion facilitates the segmentation and surface visualization of electron tomograms	7
Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete alloster	7
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	7
Conformational landscape of the mycobacterial inosine 5′-monophosphate dehydrogenase octamerization interface	7
Cryo-Electron Microscopy: The field of 1,000+ methods	7
Sequence/structural/functional relationships between Ganoderma fungal immunomodulatory proteins (gFIPs) and proteins involved in the modulation of immune response	7
The crystal structure of the H116Q mutant of NDM-1: An enzyme devoid of zinc ions	7
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	7
Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation	7
Computational structural biology: Evolution of the field	7