Journal of Structural Biology

Article	Citations
Keratin intermediate filament chains in the European common wall lizard (Podarcis muralis) and a potential keratin filament crosslinker	87
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	55
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2	39
Calcium carbonate deposition in the spicules of the sponge Heteropia glomerosa (Porifera, Calcarea)	39
Disorder-to-order transition of Synaptobrevin-2: Tracing the conformational diversity of a synaptic SNARE protein	37
Allosteric inhibition of cytosolic NADP+-dependent isocitrate dehydrogenase by oxaloacetate	37
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	37
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	35
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	34
Inter-Domain interactions Slow BoNT/A’s onset of action	33
Studying protein–protein interactions: Latest and most popular approaches	33
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	30
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	29
Multishot tomography for high-resolution in situ subtomogram averaging	29
TomoAlign: A novel approach to correcting sample motion and 3D CTF in CryoET	28
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	27
It’s noisy out there! A review of denoising techniques in cryo-electron tomography	26
Outside Front Cover	25
Outside Front Cover	24
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	23
Interaction of berberine with different forms of DNA in human telomeric region	23
Editorial Board	22
Isolation and reconstruction of cardiac mitochondria from SBEM images using a deep learning-based method	22
JBP1 and JBP3 have conserved structures but different affinity to base-J	21
Crystal structure of TbAlba1 from Trypanosoma brucei	20

Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation	20
Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2	19
3D quantification of the lacunocanalicular network on human femoral diaphysis through synchrotron radiation-based nanoCT	18
2.85 and 2.99 Å resolution structures of 110 kDa nitrite reductase determined by 200 kV cryogenic electron microscopy	18
Outside Front Cover	17
Structural modeling of two plant UDP-dependent sugar-sugar glycosyltransferases reveals a conserved glutamic acid residue that is a hallmark for sugar acceptor recognition	17
Structure and heterogeneity of a highly cargo-loaded encapsulin shell	17
Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1	17
Crystal structure of the Escherichia coli CusS kinase core	16
Focused classifications and refinements in high-resolution single particle cryo-EM analysis	16
New insight on spatial localization and microstructures of calcite-aragonite interfaces in adult shell of Haliotis tuberculata: Investigations of wild and farmed abalones by FTIR and Raman mapping	16
Structural and dynamic insights into the HNH nuclease of divergent Cas9 species	16
Outside Front Cover	16
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography	16
Outside Front Cover	15
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region	15
Local defocus estimation in single particle analysis in cryo-electron microscopy	15
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase	15
Daisy: An integrated repeat protein curation service	15
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism	15
Three dimensional structures of the inner and outer pig petrous bone using FIB-SEM: Implications for development and ancient DNA preservation	14
EMDA: A Python package for Electron Microscopy Data Analysis	14
Common structural features in some of the sequentially distant neurotransmitter transporters N-termini	14
Outside Front Cover	13
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity	13
Structural analysis of the water channel AQP2 by single-particle cryo-EM	12
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	12
Genetic basis of stony coral biomineralization: History, trends and future prospects	12
Cell recognition based on atomic force microscopy and modified residual neural network	12
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	12
Outside Front Cover	12
Integrating on-grid immunogold labeling and cryo-electron tomography to reveal photosystem II structure and spatial distribution in thylakoid membranes	11
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	11
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	11
2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53	11
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	11
Biochemical, structural and dynamical studies reveal strong differences in the thermal-dependent allosteric behavior of two extremophilic lactate dehydrogenases	11
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	11
Outside Front Cover	10
Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis	10
Outside Front Cover	10
Opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging	10
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	10
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	10
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	9
Structural insights into ring-building motif domains involved in bacterial sporulation	9
Journal of Structural Biology – Paper of the Year 2022	9
Editorial Board	9
Dense intracellular ion pools in unicellular organisms	9
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	8

Conformational landscape of the mycobacterial inosine 5′-monophosphate dehydrogenase octamerization interface	8
Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7	8
MEPSi: A tool for simulating tomograms of membrane-embedded proteins	8
Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography	8
Characterization of heterogeneity in nanodisc samples using Feret signatures	8
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor	8
Desmosomal protein structure and function and the impact of disease-causing mutations	8
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	8
Computational structural biology: Evolution of the field	7
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	7
The crystal structure of the H116Q mutant of NDM-1: An enzyme devoid of zinc ions	7
Insight into structural biophysics from solution X-ray scattering	7
Journal of Structural Biology – Paper of the Year 2021	7
Effects of Xylanase A double mutation on substrate specificity and structural dynamics	7
Structure and self-association of Arrestin-1	7
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	7
The role of tandem repeats in bacterial functional amyloids	7
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	7
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	7
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata	7
3D distribution of biomineral and chitin matrix in the stomatopod dactyl club by high energy XRD-CT	7
Cryo-Electron Microscopy: The field of 1,000+ methods	7
Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete alloster	7
Evolution and biomineralization of pteropod shells	7
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	7
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	7
Mean curvature motion facilitates the segmentation and surface visualization of electron tomograms	7
Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation	7
Identification and evaluation of potential inhibitor molecules against TcyA from Candidatus Liberibacter asiaticus	7
NUDIM: A non-uniform fast Fourier transform based dual-space constraint iterative reconstruction method in biological electron tomography	6
Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA	6
A new algorithm for particle weighted subtraction to decrease signals from unwanted components in single particle analysis	6
Classification of helical polymers with deep-learning language models	6
Phylogenetic analysis and homology modelling of a new Cry8A crystal protein expressed in a sporulating soil bacterium	6
Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex	6
Computational Engineering of siderocalin to modulate its binding affinity to the antihypertension drug candesartan	6
NMR and semi-synthesis in synergy to study protein regulation	6
The intricacies of tooth enamel: Embryonic origin, development and human genetics	6
Towards in situ high-resolution imaging of viruses and macromolecular complexes using cryo-electron tomography	6
A non-parametric approach to particle picking in all frames	6
Prokaryotic membrane coat - like proteins: An update	6
Statistical proofs of the interdependence between nearest neighbor effects on polypeptide backbone conformations	6
Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study	6
Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation	6
Editorial Board	6
Determinants of site-selectivity in human ileal bile acid-binding protein by NMR dynamic analysis of a functionally-impaired mutant	6
Editorial Board	6
Transcriptional activity and splicing factors are preserved during physiological apoptosis	6
Cryo-EM structure of bacterial nitrilase reveals insight into oligomerization, substrate recognition, and catalysis	6
Kinetic and structural studies of gamma-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis	6
Sumoylation and the oncogenic E17K mutation affect AKT1 subcellular distribution and impact on Nanog-binding dynamics to chromatin in embryonic stem cells	6
Outside Front Cover	5
Comparison of the global crystallographic texture of minerals in the shells of Bathymodiolus thermophilus Kenk et B.R. Wilson, 1985 and species of the genus Mytilus Linnaeus, 1758	5
A review of the approaches used to solve sub-100 kDa membrane proteins by cryo-electron microscopy	5
Three-dimensional cellular architecture of the sigmoid filament in Trichomonas vaginalis	5
GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers	5
RosettaHDX: Predicting antibody-antigen interaction from hydrogen-deuterium exchange mass spectrometry data	5
Journal of Structural Biology – Paper of the Year 2021	5
High-throughput segmentation, data visualization, and analysis of sea star skeletal networks	5
Outside Front Cover	5
Editorial Board	5
Revisiting the Ramachandran plot based on statistical analysis of static and dynamic characteristics of protein structures	5
Exploring α-synuclein stability under the external electrostatic field: Effect of repeat unit	5
Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids	5
Exploring the folding landscape of leptin: Insights into threading pathways	5
Unveiling success determinants for AMB-assisted phase expansion of fusion proteins in ARP/wARP	5
The SIRAH force field: A suite for simulations of complex biological systems at the coarse-grained and multiscale levels	5
Epitope-Analyzer: A structure-based webtool to analyze broadly neutralizing epitopes	5
Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core	5
Recent advances in the application of atomic force microscopy to structural biology	5
Editorial Board	5
Lack of embryonic skeletal muscle in mice leads to abnormal mineral deposition and growth	5
Selective signal enhancement in Fourier space as a tool for discovering ultrastructural organization of macromolecules from in situ TEM	5
Three-dimensional reconstruction of Magnetofaba australis strain IT-1: Magnetosome chain position with respect to flagella	5
Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM	5
SAM1 domain of SASH1 harbors distinctive structural heterogeneity	5
CryoSamba: Self-supervised deep volumetric denoising for cryo-electron tomography data	5
Crystal structure of the potato leafroll virus coat protein and implications for viral assembly	5
New insights into the effect of mutations on affibody-Fc interaction, a molecular dynamics simulation approach	4
Structure guided mutagenesis reveals the substrate determinants of guanine deaminase	4

OpenFIBSEM: A universal API for FIBSEM control	4
Structural and biophysical characterization of PadR family protein Rv0047c of Mycobacterium tuberculosis H37Rv	4
The structure of exopolyphosphatase (PPX) from Porphyromonas gingivalis in complex with substrate analogs and magnesium ions reveals the basis for polyphosphate processivity	4
Insights into the dynamic interactions at chemokine-receptor interfaces and mechanistic models of chemokine binding	4
Four-dimensional microED of conformational dynamics in protein microcrystals on the femto-to-microsecond timescales	4
Cryo-EM density maps adjustment for subtraction, consensus and sharpening	4
Electron-counting MicroED data with the K2 and K3 direct electron detectors	4
Visualizing transiently associated catalytic domains in assembly-line biosynthesis using cryo-electron microscopy	4
Ice thickness control and measurement in the VitroJet for time-efficient single particle structure determination	4
Optimal 3D angular sampling with applications to cryo-EM problems	4
Outlier removal in cryo-EM via radial profiles	4
Phylogeny and structural peculiarities of the EB proteins of diatoms	4
Cryo-EM image alignment: From pair-wise to joint with deep unsupervised difference learning	4
Characterization of conformational flexibility in protein structures by applying artificial intelligence to molecular modeling	4
Why does the first protein repeat often become the only one?	4
The repetitive structure of DNA clamps: An overlooked protein tandem repeat	4
Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite	4
A computational approach to predict the effects of missense mutations on protein amyloidogenicity: A case study in hereditary transthyretin cardiomyopathy	3
Investigating the role of elastin and extracellular matrix damage in cardiovascular calcification	3
Integration of software tools for integrative modeling of biomolecular systems	3
A strained N-capping motif in α-helices of βαβ-units	3
A feature-guided, focused 3D signal permutation method for subtomogram averaging	3
Characterization of the growth plate-bone interphase region using cryo-FIB SEM 3D volume imaging	3
Robust ab initio solution of the cryo-EM reconstruction problem at low resolution with small data sets	3
Correlative transmission electron microscopy and high-resolution hard X-ray fluorescence microscopy of cell sections to measure trace element concentrations at the organelle level	3
Biological applications of the scanning transmission electron microscope	3
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes	3
A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate	3
Rapid tool for cell nanoarchitecture integrity assessment	3
Crystal structure of the pheromone Er-13 from the ciliate Euplotes raikovi, with implications for a protein–protein association model in pheromone/receptor interactions	3
Different strategies towards strength: Unveiling the role of Zn vs Mn/Ca and chitin arrangement in scorpion stingers	3
A STRP-ed definition of Structured Tandem Repeats in Proteins	3
Chemically cross-linked hydrogels from repetitive protein arrays	3
Structural principles of CRISPR-Cas enzymes used in nucleic acid detection	3
Dengue virus-host interactions: Structural and mechanistic insights for future therapeutic strategies	3
Structure and dynamics of the mitochondrial DNA-compaction factor Abf2 from S. cerevisiae	2
Smart data collection for CryoEM	2
Engineering of brick and staple components for ordered assembly of synthetic repeat proteins	2
Lattice micropatterning for cryo-electron tomography studies of cell-cell contacts	2
Characterization of SARS-CoV-2 nucleocapsid protein oligomers	2
Outside Front Cover	2
Gold nanomaterials and their potential use as cryo-electron tomography labels	2
Structural and biochemical basis for the substrate specificity of Pad-1, an indole-3-pyruvic acid aminotransferase in auxin homeostasis	2
Phylogenetic analysis and structural studies of heteromeric acetyl-CoA carboxylase from the oleaginous Amazonian microalgae Ankistrodesmus sp.: Insights into the BC and BCCP subunits	2
Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data	2
Crystal structure of the Mycobacterium tuberculosis VirS regulator reveals its interaction with the lead compound SMARt751	2
Outside Front Cover	2
Multimodal analysis and comparison of stoichiometric and structural characteristics of parosteal and conventional osteosarcoma with massive sclerosis in human bone	2
Deep generative modeling for volume reconstruction in cryo-electron microscopy	2
Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538	2
Crystal structure of the anti-CRISPR repressor Aca2	2
An inducible model for medial calcification based on matrix Gla protein deficiency	2
Disulfide bonds enhance thermal stability and thumb region drives activity of the glycoside hydrolase 11 xylanase rMxylcd	2
Cage versus sheet: Probing the Determinants of Protein – Cucurbit[7]uril Crystalline Architectures	2
Conformational ensemble of amyloid-forming semenogelin 1 peptide SEM1(68–107) by NMR spectroscopy and MD simulations	2
Bone strength and residual compressive stress in apatite crystals	2
Markov state modeling of membrane transport proteins	2
The crystal structure of Mycobacterium thermoresistibile MurE ligase reveals the binding mode of the substrate m-diaminopimelate	2
Perspective: Emerging strategies for determining atomic-resolution structures of macromolecular complexes within cells	2
Effects of Gα C-terminal deletion on the intrinsic GDP release/GTPase activity and conformational dynamics	2
Structural organization of the organic sheath that delineates extracellular seta silicification in diatoms	2
Off-axis electron holography of unstained bacteriophages: Towards electrostatic potential measurement of biological samples	2
Montage electron tomography of vitrified specimens	2
The role of propeptide-mediated autoinhibition and intermolecular chaperone in the maturation of cognate catalytic domain in leucine aminopeptidase	2
From in-silico screening to in-vitro evaluation: Enhancing the detection of Microcystins with engineered PP1 mutant variants	2
Accurate, automatic determination of astigmatism and phase with Ctfplotter in IMOD	2
Role of a high centrality residue in protein dynamics and thermal stability	2