Journal of Structural Biology

Article	Citations
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	46
Characterization of NMDA receptor Allostery modulation	42
Calcium carbonate deposition in the spicules of the sponge Heteropia glomerosa (Porifera, Calcarea)	39
Allosteric inhibition of cytosolic NADP+-dependent isocitrate dehydrogenase by oxaloacetate	38
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	38
Keratin intermediate filament chains in the European common wall lizard (Podarcis muralis) and a potential keratin filament crosslinker	37
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2	37
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	37
Disorder-to-order transition of Synaptobrevin-2: Tracing the conformational diversity of a synaptic SNARE protein	36
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	35
Inter-Domain interactions Slow BoNT/A’s onset of action	35
TomoAlign: A novel approach to correcting sample motion and 3D CTF in CryoET	31
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	31
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	31
Studying protein–protein interactions: Latest and most popular approaches	27
Outside Front Cover	25
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	25
Multishot tomography for high-resolution in situ subtomogram averaging	25
Isolation and reconstruction of cardiac mitochondria from SBEM images using a deep learning-based method	24
Interaction of berberine with different forms of DNA in human telomeric region	24
Outside Front Cover	23
It’s noisy out there! A review of denoising techniques in cryo-electron tomography	21
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	20
ArtiaX: geometric models, camera paths and image processing tools	20
Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation	19

Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2	19
Editorial Board	19
Structure and heterogeneity of a highly cargo-loaded encapsulin shell	19
JBP1 and JBP3 have conserved structures but different affinity to base-J	19
Insights into the pathogenic mechanisms associated with the SARS-CoV-2 spike protein	19
3D quantification of the lacunocanalicular network on human femoral diaphysis through synchrotron radiation-based nanoCT	18
Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1	17
Crystal structure of the Escherichia coli CusS kinase core	17
Focused classifications and refinements in high-resolution single particle cryo-EM analysis	17
Structural and dynamic insights into the HNH nuclease of divergent Cas9 species	17
Outside Front Cover	17
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region	17
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase	17
Nickel-NTA lipid-monolayer affinity grids allow for high-resolution structure determination by cryo-EM	16
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography	16
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism	16
Preferential binding as a driving mechanism of lipid domains formation	15
Common structural features in some of the sequentially distant neurotransmitter transporters N-termini	15
Local defocus estimation in single particle analysis in cryo-electron microscopy	15
New insight on spatial localization and microstructures of calcite-aragonite interfaces in adult shell of Haliotis tuberculata: Investigations of wild and farmed abalones by FTIR and Raman mapping	15
EMDA: A Python package for Electron Microscopy Data Analysis	13
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	13
Daisy: An integrated repeat protein curation service	13
Three dimensional structures of the inner and outer pig petrous bone using FIB-SEM: Implications for development and ancient DNA preservation	13
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity	13
Outside Front Cover	13
Outside Front Cover	13
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	12
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	11
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	11
Genetic basis of stony coral biomineralization: History, trends and future prospects	11
Cholesterol crystals in reservosomes of Trypanosoma cruzi	11
2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53	11
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	11
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	11
Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis	10
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	10
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	10
Structural analysis of the water channel AQP2 by single-particle cryo-EM	10
Outside Front Cover	10
Cell recognition based on atomic force microscopy and modified residual neural network	10
Outside Front Cover	9
Opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging	9
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor	9
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	9
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	9
Outside Front Cover	8
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	8
Editorial Board	8
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	8

Characterization of heterogeneity in nanodisc samples using Feret signatures	8
MEPSi: A tool for simulating tomograms of membrane-embedded proteins	8
Outside Front Cover	8
Structural insights into ring-building motif domains involved in bacterial sporulation	8
Dense intracellular ion pools in unicellular organisms	8
Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7	8
Journal of Structural Biology – Paper of the Year 2022	8
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	8
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	8
The crystal structure of the H116Q mutant of NDM-1: An enzyme devoid of zinc ions	7
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	7
Conformational landscape of the mycobacterial inosine 5′-monophosphate dehydrogenase octamerization interface	7
Sequence/structural/functional relationships between Ganoderma fungal immunomodulatory proteins (gFIPs) and proteins involved in the modulation of immune response	7
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	7
Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation	7
Structure and self-association of Arrestin-1	7
Computational structural biology: Evolution of the field	7
The role of tandem repeats in bacterial functional amyloids	7
Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography	7
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata	7
Insight into structural biophysics from solution X-ray scattering	7
The intricacies of tooth enamel: Embryonic origin, development and human genetics	7
3D distribution of biomineral and chitin matrix in the stomatopod dactyl club by high energy XRD-CT	7
Evolution and biomineralization of pteropod shells	7
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	7
Effects of Xylanase A double mutation on substrate specificity and structural dynamics	7
Mean curvature motion facilitates the segmentation and surface visualization of electron tomograms	7
Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete alloster	7
Cryo-Electron Microscopy: The field of 1,000+ methods	7
Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA	6
CryoSamba: Self-supervised deep volumetric denoising for cryo-electron tomography data	6
Determinants of site-selectivity in human ileal bile acid-binding protein by NMR dynamic analysis of a functionally-impaired mutant	6
Identification and evaluation of potential inhibitor molecules against TcyA from Candidatus Liberibacter asiaticus	6
Editorial Board	6
Cryo-EM structure of bacterial nitrilase reveals insight into oligomerization, substrate recognition, and catalysis	6
Computational Engineering of siderocalin to modulate its binding affinity to the antihypertension drug candesartan	6
Editorial Board	6
A new algorithm for particle weighted subtraction to decrease signals from unwanted components in single particle analysis	6
Towards in situ high-resolution imaging of viruses and macromolecular complexes using cryo-electron tomography	6
Prokaryotic membrane coat - like proteins: An update	6
Classification of helical polymers with deep-learning language models	6
Editorial Board	6
Phylogenetic analysis and homology modelling of a new Cry8A crystal protein expressed in a sporulating soil bacterium	6
Journal of Structural Biology – Paper of the Year 2021	6
A non-parametric approach to particle picking in all frames	6
Transcriptional activity and splicing factors are preserved during physiological apoptosis	6
A generalist deep-learning volume segmentation tool for volume electron microscopy of biological samples	5
Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study	5
Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation	5
Three-dimensional reconstruction of Magnetofaba australis strain IT-1: Magnetosome chain position with respect to flagella	5
Selective signal enhancement in Fourier space as a tool for discovering ultrastructural organization of macromolecules from in situ TEM	5
SAM1 domain of SASH1 harbors distinctive structural heterogeneity	5
High-throughput segmentation, data visualization, and analysis of sea star skeletal networks	5
NMR and semi-synthesis in synergy to study protein regulation	5
Epitope-Analyzer: A structure-based webtool to analyze broadly neutralizing epitopes	5
Kinetic and structural studies of gamma-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis	5
Journal of Structural Biology – Paper of the Year 2021	5
Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core	5
Crystal structure of the potato leafroll virus coat protein and implications for viral assembly	5
GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers	5
Sumoylation and the oncogenic E17K mutation affect AKT1 subcellular distribution and impact on Nanog-binding dynamics to chromatin in embryonic stem cells	5
Statistical proofs of the interdependence between nearest neighbor effects on polypeptide backbone conformations	5
The SIRAH force field: A suite for simulations of complex biological systems at the coarse-grained and multiscale levels	5
Unveiling success determinants for AMB-assisted phase expansion of fusion proteins in ARP/wARP	5
RosettaHDX: Predicting antibody-antigen interaction from hydrogen-deuterium exchange mass spectrometry data	5
Exploring the folding landscape of leptin: Insights into threading pathways	5
Outlier removal in cryo-EM via radial profiles	4
Recent advances in the application of atomic force microscopy to structural biology	4
Three-dimensional cellular architecture of the sigmoid filament in Trichomonas vaginalis	4
A review of the approaches used to solve sub-100 kDa membrane proteins by cryo-electron microscopy	4
Electron-counting MicroED data with the K2 and K3 direct electron detectors	4
Ice thickness control and measurement in the VitroJet for time-efficient single particle structure determination	4
Binding of an N protein peptide to M protein of a bat coronavirus	4
Cryo-EM density maps adjustment for subtraction, consensus and sharpening	4
Editorial Board	4
Exploring α-synuclein stability under the external electrostatic field: Effect of repeat unit	4
Revisiting the Ramachandran plot based on statistical analysis of static and dynamic characteristics of protein structures	4
Editorial Board	4
Characterization of conformational flexibility in protein structures by applying artificial intelligence to molecular modeling	4
Visualizing transiently associated catalytic domains in assembly-line biosynthesis using cryo-electron microscopy	4

New insights into the effect of mutations on affibody-Fc interaction, a molecular dynamics simulation approach	4
Outside Front Cover	4
Lack of embryonic skeletal muscle in mice leads to abnormal mineral deposition and growth	4
Comparison of the global crystallographic texture of minerals in the shells of Bathymodiolus thermophilus Kenk et B.R. Wilson, 1985 and species of the genus Mytilus Linnaeus, 1758	4
Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids	4
Outside Front Cover	4
OpenFIBSEM: A universal API for FIBSEM control	4
Structural and biophysical characterization of PadR family protein Rv0047c of Mycobacterium tuberculosis H37Rv	4
Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite	4
Four-dimensional microED of conformational dynamics in protein microcrystals on the femto-to-microsecond timescales	4
Characterization of the growth plate-bone interphase region using cryo-FIB SEM 3D volume imaging	3
Montage electron tomography of vitrified specimens	3
Structural principles of CRISPR-Cas enzymes used in nucleic acid detection	3
Integration of software tools for integrative modeling of biomolecular systems	3
Different strategies towards strength: Unveiling the role of Zn vs Mn/Ca and chitin arrangement in scorpion stingers	3
Insights into the dynamic interactions at chemokine-receptor interfaces and mechanistic models of chemokine binding	3
Optimal 3D angular sampling with applications to cryo-EM problems	3
Biological applications of the scanning transmission electron microscope	3
A feature-guided, focused 3D signal permutation method for subtomogram averaging	3
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes	3
Structural organization of the organic sheath that delineates extracellular seta silicification in diatoms	3
Rapid tool for cell nanoarchitecture integrity assessment	3
Chemically cross-linked hydrogels from repetitive protein arrays	3
Why does the first protein repeat often become the only one?	3
Crystal structure of the pheromone Er-13 from the ciliate Euplotes raikovi, with implications for a protein–protein association model in pheromone/receptor interactions	3
Dengue virus-host interactions: Structural and mechanistic insights for future therapeutic strategies	3
A strained N-capping motif in α-helices of βαβ-units	3
Robust ab initio solution of the cryo-EM reconstruction problem at low resolution with small data sets	3
A STRP-ed definition of Structured Tandem Repeats in Proteins	3
The repetitive structure of DNA clamps: An overlooked protein tandem repeat	3
A computational approach to predict the effects of missense mutations on protein amyloidogenicity: A case study in hereditary transthyretin cardiomyopathy	3
Cryo-EM image alignment: From pair-wise to joint with deep unsupervised difference learning	3
A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate	3
Investigating the role of elastin and extracellular matrix damage in cardiovascular calcification	3