Journal of Structural Biology

Article	Citations
Allosteric inhibition of cytosolic NADP+-dependent isocitrate dehydrogenase by oxaloacetate	65
Tropomyosin induces the synthesis of magnesian calcite in sea urchin spines	60
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs	45
Deep Learning-based structure modelling illuminates structure and function in uncharted regions of β-solenoid fold space	45
Calcium carbonate deposition in the spicules of the sponge Heteropia glomerosa (Porifera, Calcarea)	41
Characterization of NMDA receptor Allostery modulation	40
Dual-colour super-resolution cryoCLEM in mammalian cells using the fluorescent proteins rsTagRFP and rsEGFP2	39
ContinuousFlex: Software package for analyzing continuous conformational variability of macromolecules in cryo electron microscopy and tomography data	38
High-resolution single-particle imaging at 100–200 keV with the Gatan Alpine direct electron detector	34
Inter-Domain interactions Slow BoNT/A’s onset of action	34
Structure of the type VI secretion protein VgrS from Salmonella Typhimurium	29
Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging	27
Outside Front Cover	26
Multishot tomography for high-resolution in situ subtomogram averaging	24
Focused ion beam-SEM 3D study of osteodentin in the teeth of the Atlantic wolfish Anarhichas lupus	23
Studying protein–protein interactions: Latest and most popular approaches	23
Outside Front Cover	22
Interaction of berberine with different forms of DNA in human telomeric region	21
Outside Front Cover	21
Changes in Arabidopsis thaliana seedling cell wall assembly induced by treatment with Yariv reagent – Molecular features & visualization with immunocytochemistry and a fluorescent Yariv reagent	20
Comprehensive structural overview of the C-terminal ligand-binding domains of the TetR family regulators	20
Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation	18
Editorial Board	17
Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2	16
3D quantification of the lacunocanalicular network on human femoral diaphysis through synchrotron radiation-based nanoCT	16

JBP1 and JBP3 have conserved structures but different affinity to base-J	15
From selenium to sulfur: predictive modeling unveils conformational and bonding changes in selenoproteins	15
Insights into the pathogenic mechanisms associated with the SARS-CoV-2 spike protein	15
Nanostructural evolution during carious and demineralisation process of human dentine using small angle X-ray scattering tensor tomography	15
ArtiaX: geometric models, camera paths and image processing tools	14
Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1	14
Structure and heterogeneity of a highly cargo-loaded encapsulin shell	13
G-Quadruplex structures within the hfq gene regulate RNA–protein interactions in Acinetobacter baumannii	13
Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism	13
Outside Front Cover	13
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography	12
Focused classifications and refinements in high-resolution single particle cryo-EM analysis	12
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase	12
Crystal structure of the Escherichia coli CusS kinase core	12
New insight on spatial localization and microstructures of calcite-aragonite interfaces in adult shell of Haliotis tuberculata: Investigations of wild and farmed abalones by FTIR and Raman mapping	12
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region	12
Nickel-NTA lipid-monolayer affinity grids allow for high-resolution structure determination by cryo-EM	12
Local defocus estimation in single particle analysis in cryo-electron microscopy	11
Daisy: An integrated repeat protein curation service	11
Common structural features in some of the sequentially distant neurotransmitter transporters N-termini	11
Outside Front Cover	10
DeepQs: Local quality assessment of cryo-EM density map by deep learning map-model fit score	10
Three dimensional structures of the inner and outer pig petrous bone using FIB-SEM: Implications for development and ancient DNA preservation	10
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy	10
Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody	10
Local microenvironments of capsomer variants in the PBCV-1	10
Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity	10
Tooth acellular extrinsic fibre cementum incremental lines in humans are formed by parallel branched Sharpey’s fibres and not by its mineral phase	10
Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane	10
Preferential binding as a driving mechanism of lipid domains formation	10
Outside Front Cover	9
Distribution and size of scallop patterns at the human dentin enamel junction revealed with micro tomography	9
Corrigendum to “High-resolution single particle analysis using a scintillator camera XF416 on CRYOARM300II at 300 kV”. [J. Struct. Biol. 218(1) (2026) 108286]	9
Cell recognition based on atomic force microscopy and modified residual neural network	9
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis	9
2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53	9
Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins	9
Cholesterol crystals in reservosomes of Trypanosoma cruzi	9
A glimpse into the hidden world of the flexible C-terminal protein binding domains of human RAD52	9
Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex	9
Structural analysis of the water channel AQP2 by single-particle cryo-EM	9
Outside Front Cover	9
Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth	8
Outside Front Cover	8
Sub-micrometric spatial distribution of amorphous and crystalline carbonates in biogenic crystals using coherent Raman microscopy	8
Morphological and genetic mechanisms underlying the plasticity of the coral Porites astreoides across depths in Bermuda	8
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor	8
Journal of Structural Biology – Paper of the Year 2022	8
Editorial Board	8
Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain	8

Conformational landscape of the mycobacterial inosine 5′-monophosphate dehydrogenase octamerization interface	8
Outside Front Cover	8
Characterization of heterogeneity in nanodisc samples using Feret signatures	8
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly	8
MEPSi: A tool for simulating tomograms of membrane-embedded proteins	8
Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation	7
3D distribution of biomineral and chitin matrix in the stomatopod dactyl club by high energy XRD-CT	7
The role of tandem repeats in bacterial functional amyloids	7
Outside Front Cover	7
The crystal structure of the H116Q mutant of NDM-1: An enzyme devoid of zinc ions	7
Bioinformatic and experimental characterization of the RBM15 RNA binding protein	7
Cryo-Electron Microscopy: The field of 1,000+ methods	7
A new algorithm for particle weighted subtraction to decrease signals from unwanted components in single particle analysis	7
Identification and demonstration of roGFP2 as an environmental sensor for cryogenic correlative light and electron microscopy	7
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis	7
Sequence/structural/functional relationships between Ganoderma fungal immunomodulatory proteins (gFIPs) and proteins involved in the modulation of immune response	7
Mechanistic study of PDE5A inhibitors from the prepared folium of Epimedium sagittatum maxim	7
Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete alloster	7
Announcement: Journal of Structural Biology: Paper of the year	7
Effects of Xylanase A double mutation on substrate specificity and structural dynamics	7
Computational structural biology: Evolution of the field	7
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E	7
Insight into structural biophysics from solution X-ray scattering	7
Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata	7
Towards in situ high-resolution imaging of viruses and macromolecular complexes using cryo-electron tomography	6
Determinants of site-selectivity in human ileal bile acid-binding protein by NMR dynamic analysis of a functionally-impaired mutant	6
Journal of Structural Biology – Paper of the Year 2021	6
Transcriptional activity and splicing factors are preserved during physiological apoptosis	6
Phylogenetic analysis and homology modelling of a new Cry8A crystal protein expressed in a sporulating soil bacterium	6
Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study	6
A non-parametric approach to particle picking in all frames	6
Identification and evaluation of potential inhibitor molecules against TcyA from Candidatus Liberibacter asiaticus	6
Structure and self-association of Arrestin-1	6
Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA	6
Cryo-EM structure of bacterial nitrilase reveals insight into oligomerization, substrate recognition, and catalysis	6
Sumoylation and the oncogenic E17K mutation affect AKT1 subcellular distribution and impact on Nanog-binding dynamics to chromatin in embryonic stem cells	6
Prokaryotic membrane coat - like proteins: An update	6
The intricacies of tooth enamel: Embryonic origin, development and human genetics	6
Membrane and vesicle structure detection in cryo-electron tomography based on deep learning	6
Editorial Board	6
Editorial Board	6
Classification of helical polymers with deep-learning language models	6
NMR and semi-synthesis in synergy to study protein regulation	6
Journal of Structural Biology – Paper of the Year 2021	5
Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation	5
CryoSamba: Self-supervised deep volumetric denoising for cryo-electron tomography data	5
Three-dimensional reconstruction of Magnetofaba australis strain IT-1: Magnetosome chain position with respect to flagella	5
High-throughput segmentation, data visualization, and analysis of sea star skeletal networks	5
GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers	5
Statistical proofs of the interdependence between nearest neighbor effects on polypeptide backbone conformations	5
Kinetic and structural studies of gamma-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis	5
The SIRAH force field: A suite for simulations of complex biological systems at the coarse-grained and multiscale levels	5
Unveiling success determinants for AMB-assisted phase expansion of fusion proteins in ARP/wARP	5
RosettaHDX: Predicting antibody-antigen interaction from hydrogen-deuterium exchange mass spectrometry data	5
GNN2Pfam: Integrating protein sequence and structure with graph neural networks for Pfam domain annotation	5
Computational Engineering of siderocalin to modulate its binding affinity to the antihypertension drug candesartan	5
A generalist deep-learning volume segmentation tool for volume electron microscopy of biological samples	5
Exploring the folding landscape of leptin: Insights into threading pathways	5
CDP-alcohol phosphotransferases: Structures and function of highly diverse sub-classes within a protein family	4
Selective signal enhancement in Fourier space as a tool for discovering ultrastructural organization of macromolecules from in situ TEM	4
Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids	4
Revisiting the Ramachandran plot based on statistical analysis of static and dynamic characteristics of protein structures	4
Outside Front Cover	4
Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core	4
A review of the approaches used to solve sub-100 kDa membrane proteins by cryo-electron microscopy	4
Three-dimensional cellular architecture of the sigmoid filament in Trichomonas vaginalis	4
Editorial Board	4
Editorial Board	4
Recent advances in the application of atomic force microscopy to structural biology	4
SAM1 domain of SASH1 harbors distinctive structural heterogeneity	4
Exploring α-synuclein stability under the external electrostatic field: Effect of repeat unit	4
Comparison of the global crystallographic texture of minerals in the shells of Bathymodiolus thermophilus Kenk et B.R. Wilson, 1985 and species of the genus Mytilus Linnaeus, 1758	4
Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite	4
Four-dimensional microED of conformational dynamics in protein microcrystals on the femto-to-microsecond timescales	4
Hurdles and advancements in experimental membrane protein structural biology	3
Binding of an N protein peptide to M protein of a bat coronavirus	3
OpenFIBSEM: A universal API for FIBSEM control	3
Announcement: Journal of Structural Biology: Paper of the year	3
Precise ligand-selective mechanism at the fab domain of a tau-recognizing antibody	3
Cryo-EM image alignment: From pair-wise to joint with deep unsupervised difference learning	3

The repetitive structure of DNA clamps: An overlooked protein tandem repeat	3
Chemically cross-linked hydrogels from repetitive protein arrays	3
Insights into the dynamic interactions at chemokine-receptor interfaces and mechanistic models of chemokine binding	3
Outlier removal in cryo-EM via radial profiles	3
Electron-counting MicroED data with the K2 and K3 direct electron detectors	3
Prediction of a structural change in the orientation of the cytoplasmic signaling unit of human Toll-like receptor 9 upon binding of agonistic and antagonistic DNA molecules	3
Characterization of conformational flexibility in protein structures by applying artificial intelligence to molecular modeling	3
Biological applications of the scanning transmission electron microscope	3
Robust ab initio solution of the cryo-EM reconstruction problem at low resolution with small data sets	3
Ice thickness control and measurement in the VitroJet for time-efficient single particle structure determination	3
Lack of embryonic skeletal muscle in mice leads to abnormal mineral deposition and growth	3
New insights into the effect of mutations on affibody-Fc interaction, a molecular dynamics simulation approach	3
Structural and biophysical characterization of PadR family protein Rv0047c of Mycobacterium tuberculosis H37Rv	3
Solution 3D structure and conformational flexibility of the endothelial monocyte activating polypeptide II (EMAP II) revealed by NMR spectroscopy and molecular dynamics simulations	3
Why does the first protein repeat often become the only one?	3
Optimal 3D angular sampling with applications to cryo-EM problems	3
A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate	2
A feature-guided, focused 3D signal permutation method for subtomogram averaging	2
Different strategies towards strength: Unveiling the role of Zn vs Mn/Ca and chitin arrangement in scorpion stingers	2
Disulfide bonds enhance thermal stability and thumb region drives activity of the glycoside hydrolase 11 xylanase rMxylcd	2
Off-axis electron holography of unstained bacteriophages: Towards electrostatic potential measurement of biological samples	2
Montage electron tomography of vitrified specimens	2
Disorder, dynamics, and regulation of proteins and nucleic acids	2
Outside Front Cover	2
Deep geometric framework to predict antibody–antigen binding affinity	2
Structural and biochemical basis for the substrate specificity of Pad-1, an indole-3-pyruvic acid aminotransferase in auxin homeostasis	2
Characterization of SARS-CoV-2 nucleocapsid protein oligomers	2
Effects of Gα C-terminal deletion on the intrinsic GDP release/GTPase activity and conformational dynamics	2
Structural basis for spectral red shift and UVA absorption in the microalgal water-soluble astaxanthin-binding protein AstaP-pink1	2
A strained N-capping motif in α-helices of βαβ-units	2
Gold nanomaterials and their potential use as cryo-electron tomography labels	2
A STRP-ed definition of Structured Tandem Repeats in Proteins	2
Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538	2
Dengue virus-host interactions: Structural and mechanistic insights for future therapeutic strategies	2
Outside Front Cover	2
Accurate, automatic determination of astigmatism and phase with Ctfplotter in IMOD	2
Structure and dynamics of the mitochondrial DNA-compaction factor Abf2 from S. cerevisiae	2
The crystal structure of Mycobacterium thermoresistibile MurE ligase reveals the binding mode of the substrate m-diaminopimelate	2
High-Resolution single particle analysis using a scintillator camera XF416 on CRYOARM300II at 300 kV	2
Structural organization of the organic sheath that delineates extracellular seta silicification in diatoms	2
A computational approach to predict the effects of missense mutations on protein amyloidogenicity: A case study in hereditary transthyretin cardiomyopathy	2
Structural characterization of Meiothermus ruber LOV domain	2
Smart data collection for CryoEM	2
Investigating the role of elastin and extracellular matrix damage in cardiovascular calcification	2
Cage versus sheet: Probing the Determinants of Protein – Cucurbit[7]uril Crystalline Architectures	2
An inducible model for medial calcification based on matrix Gla protein deficiency	2
Bone strength and residual compressive stress in apatite crystals	2
Multimodal analysis and comparison of stoichiometric and structural characteristics of parosteal and conventional osteosarcoma with massive sclerosis in human bone	2
Phylogenetic analysis and structural studies of heteromeric acetyl-CoA carboxylase from the oleaginous Amazonian microalgae Ankistrodesmus sp.: Insights into the BC and BCCP subunits	2
Engineering of brick and staple components for ordered assembly of synthetic repeat proteins	2
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes	2
Deep generative modeling for volume reconstruction in cryo-electron microscopy	2