OOIR: Observatory of International Research

Papers

(The TQCC of Genes Chromosomes & Cancer is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Emerging soft tissue tumors with kinase fusions: An overview of the recent literature with an emphasis on diagnostic criteria	67
Soft tissue tumors characterized by a wide spectrum of kinase fusions share a lipofibromatosis‐like neural tumor pattern	56
PARP inhibitors in ovarian cancer: An overview of the practice‐changing trials	49
Mismatch repair deficiency: The what, how and why it is important	45
Optical genome mapping, a promising alternative to gold standard cytogenetic approaches in a series of acute lymphoblastic leukemias	43
Analysis of mutational signatures with yet another package for signature analysis	38
Translocation carcinomas of the kidney	35
The clinical heterogeneity of round cell sarcomas with EWSR1/FUS gene fusions: Impact of gene fusion type on clinical features and outcome	34
NTRK and other recently described kinase fusion positive uterine sarcomas: A review of a group of rare neoplasms	29
Fusion‐positive non‐small cell lung carcinoma: Biological principles, clinical practice, and diagnostic implications	28
DICER1‐associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing	28
NTRK testing: First results of the QuiP‐EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA‐base	27
Epithelioid hemangioma of bone harboring FOS and FOSB gene rearrangements: A clinicopathologic and molecular study	27
Comprehensive targeted next‐generation sequencing approach in the molecular diagnosis of gastrointestinal stromal tumor	27
Molecular pathogenesis and prognostication of "low‐grade'' and "high‐grade" endometrial stromal sarcoma	24
NovelPPP1CB‐ALKfusion in spindle cell tumor defined by S100 and CD34 coexpression and distinctive stromal and perivascular hyalinization	24
A novel CLTC‐FOSB gene fusion in pseudomyogenic hemangioendothelioma of bone	22
Impact of immunophenotypic characteristics on genetic subgrouping in childhood acute lymphoblastic leukemia: Tokyo Children's Cancer Study Group (TCCSG) study L04‐16	21
Functional mechanisms of miR‐192 family in cancer	20
Perivascular epithelioid cell tumors (PEComa) of the gynecologic tract	20
Wholistic approach: Transcriptomic analysis and beyond using archival material for molecular diagnosis	19
Novel morphological and genetic features of fumarate hydratase deficient renal cell carcinoma in HLRCC syndrome patients with a tailored therapeutic approach	18
Variability in retinoblastoma genome stability is driven by age and not heritability	18
Novel fusion genes in spindle cell rhabdomyosarcoma: The spectrum broadens	17
Homologous recombination deficiency in breast cancer: Implications for risk, cancer development, and therapy	17

Methylation classifiers: Brain tumors, sarcomas, and what's next	17
A novel MBTD1‐PHF1 gene fusion in endometrial stromal sarcoma: A case report and literature review	16
Hereditary leiomyomatosis and renal cell carcinoma syndrome associated uterine smooth muscle tumors: Bridging morphology and clinical screening	16
Homologous recombination repair deficiency (HRD): From biology to clinical exploitation	16
Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors	15
An update of molecular findings in uterine tumor resembling ovarian sex cord tumor and GREB1‐rearranged uterine sarcoma with variable sex‐cord differentiation	15
Assigning evidence to actionability: An introduction to variant interpretation in precision cancer medicine	15
Characterization of TERT and BRAF copy number variation in papillary thyroid carcinoma: An analysis of the cancer genome atlas study	15
Undifferentiated round cell sarcomas with novel SS18‐POU5F1 fusions	15
Pediatric fibromyxoid soft tissue tumor with PLAG1 fusion: A novel entity?	15
Aggressive morphologic variants of mantle cell lymphoma characterized with high genomic instability showing frequent chromothripsis, CDKN2A/B loss, and TP53 mutations: A multi‐in	14
A low‐grade malignant soft tissue tumor with S100 and CD34 co‐expression showing novel CDC42SE2‐BRAF fusion with distinct features	14
Recent advances in smooth muscle tumors with PGR and PLAG1 gene fusions and myofibroblastic uterine neoplasms	14
Targeted next generation sequencing of MLH1‐deficient, MLH1 promoter hypermethylated, and BRAF/RAS‐wild‐type colorectal adenocarcinomas	14
Recurrent VGLL3 fusions define a distinctive subset of spindle cell rhabdomyosarcoma with an indolent clinical course and striking predilection for the head and neck	14
Activating genomic alterations in the Gs alpha gene (GNAS) in 274 694 tumors	14
Frequency and prognostic impact of PAX5 p.P80R in pediatric acute lymphoblastic leukemia patients treated on an AIEOP‐BFM acute lymphoblastic leukemia protocol	14
Uterine inflammatory myofibroblastic tumor: First report of a ROS1 fusion	14
Update on SWI/SNF‐related gynecologic mesenchymal neoplasms: SMARCA4‐deficient uterine sarcoma and SMARCB1‐deficient vulvar neoplasms	13
KRAS/GNAS‐testing by highly sensitive deep targeted next generation sequencing improves the endoscopic ultrasound‐guided workup of suspected mucinous neoplasms of the pancreas	13
Characterization of unusual iAMP21 B‐lymphoblastic leukemia (iAMP21‐ALL) from the Mayo Clinic and Children's Oncology Group	13
GAB1‐ABL1 fusions in tumors that have histologic overlap with NTRK‐rearranged spindle cell tumors	13
SMARCA2‐NR4A3 is a novel fusion gene of extraskeletal myxoid chondrosarcoma identified by RNA next‐generation sequencing	13
Gastroblastoma with a novel EWSR1‐CTBP1 fusion presenting in adolescence	12
PLAG1‐rearrangement in a uterine leiomyosarcoma with myxoid stroma and heterologous differentiation	12
Molecular prognostication of uterine smooth muscle neoplasms: From CGH array to CINSARC signature and beyond	12
MYB rearrangements and over‐expression in T‐cell acute lymphoblastic leukemia	12
A genome‐wide study of the relationship between chromosomal abnormalities and gene expression in colorectal tumors	12
Primary myxoid and epithelioid mesenchymal tumor of the kidney with a novel GLI1‐FOXO4 fusion	12
Poly(ADP‐ribose) polymerase inhibition in pancreatic cancer	11
Gastrointestinal stromal tumors with BRAF gene fusions. A report of two cases showing low or absent KIT expression resulting in diagnostic pitfalls	11
Central nervous system sarcoma with ATXN1::DUX4 fusion expands the concept of CIC‐rearranged sarcoma	11
Expanding the clinicopathological spectrum of TGFBR3‐PLAG1 rearranged salivary gland neoplasms with myoepithelial differentiation including evidence of high‐grade transformation	11
Recurrent PTBP1::MAML2 fusions in composite hemangioendothelioma with neuroendocrine differentiation: A report of two cases involving neck lymph nodes	11
A unique epithelioid vascular neoplasm of bone characterized by EWSR1/FUS‐NFATC1/2 fusions	11
MammaPrint and BluePrint comprehensively capture the cancer hallmarks in early‐stage breast cancer patients	10
Balanced and unbalanced translocations in a multicentric series of 2843 patients with chronic lymphocytic leukemia	10
RREB1‐MKL2 fusion in a spindle cell sinonasal sarcoma: biphenotypic sinonasal sarcoma or ectomesenchymal chondromyxoid tumor in an unusual site?	10
CARMN‐NOTCH2 fusion transcript drives high NOTCH2 expression in glomus tumors of the upper digestive tract	10
Detection of MEAF6‐PHF1 translocation in an endometrial stromal nodule	10
Fusion‐associated carcinomas of the breast: Diagnostic, prognostic, and therapeutic significance	10
Single‐cell sequencing in translational cancer research and challenges to meet clinical diagnostic needs	10
Pathogenic germline variants in patients with features of hereditary renal cell carcinoma: Evidence for further locus heterogeneity	10
Targeted RNA sequencing in the routine clinical detection of fusion genes in salivary gland tumors	10
Single nucleotide polymorphism array‐based signature of low hypodiploidy in acute lymphoblastic leukemia	10
Poorly differentiated chordoma with whole‐genome doubling evolving from a SMARCB1‐deficient conventional chordoma: A case report	9
Characterization of genetically defined sporadic and hereditary type 1 papillary renal cell carcinoma cell lines	9
Sclerosing TSC1 mutated renal cell carcinoma: An unusual pattern mimicking MITF family translocation renal cell carcinoma	9
Analysis of 11 candidate genes in 849 adult patients with suspected hereditary cancer predisposition	9
MLLT10 rearranged acute leukemia: Incidence, prognosis, and possible therapeutic strategies	9

Novel morphologic findings in PLAG1‐rearranged soft tissue tumors	9
Dedifferentiated secretory breast carcinoma with fibrosarcomatous features harboring an ETV6‐NTRK3 fusion in both components	9
Immuno‐oncology gene expression profiling of formalin‐fixed and paraffin‐embedded clear cell renal cell carcinoma: Performance comparison of the NanoString nCounter technology with targeted	9
Germline MUTYH mutations and high‐grade gliomas: Novel evidence for a potential association	9
circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype‐definition in small cell lung cancer	9
Sarcomas with sclerotic epithelioid phenotype harboring novel EWSR1‐SSX1 fusions	9
Spindle cell neoplasm with EML4‐ALK gene fusion presenting as an intraosseous vertebral mass	9
Fusion‐positive salivary gland carcinomas	8
A novel BRD4‐LEUTX fusion in a pediatric sarcoma with epithelioid morphology and diffuse S100 expression	8
Novel CTNND2‐TERT fusion in a spindle cell liposarcoma	8
Identification of tumors with NRG1 rearrangement, including a novel putative pathogenic UNC5D‐NRG1 gene fusion in prostate cancer by data‐drilling a de‐identified t	8
Quantification of NG2‐positivity for the precise prediction of KMT2A gene rearrangements in childhood acute leukemia	8
BRAF V600E and previously unidentified KRAS G12C mutations in odontogenic tumors may affect MAPK activation differently depending on tumor type	8
RREB1::MRTFB fusion‐positive extra‐glossal mesenchymal neoplasms: A series of five cases expanding their anatomic distribution and highlighting significant morphological and phenotypic diversit	8
Digenic inheritance of MSH6 and MUTYH variants in familial colorectal cancer	8
Recurrent loss of chromosome 22 and SMARCB1 deletion in extra‐axial chordoma: A clinicopathological and molecular analysis	8
Clinicopathologic and survival correlates of embryonal rhabdomyosarcoma driven by RAS/RAF mutations	8
Activation of PLAG1 and HMGA2 by gene fusions involving the transcriptional regulator gene NFIB	8
Chromosomal instability upregulates interferon in acute myeloid leukemia	8
Prognostic significance of the MDM2/HMGA2 ratio and histological tumor grade in dedifferentiated liposarcoma	8
Expanding the spectrum of GLI1‐altered mesenchymal tumors—A high‐grade uterine sarcoma harboring a novel PAMR1::GLI1 fusion and literature review of GLI1‐altered mesenchyma	7
N‐terminus DUX4‐immunohistochemistry is a reliable methodology for the diagnosis of DUX4‐fused B‐lymphoblastic leukemia/lymphoma (N‐terminus DUX4 IHC for DUX4<	7
Sustained remission after ruxolitinib and chimeric antigen receptor T‐cell therapy bridged to a second allogeneic hematopoietic stem cell transplantation for relapsed Philadelphia chromosome‐like B‐ce	7
ALK‐rearranged Mesenchymal Neoplasms: A Report of 9 cases Further Expanding the Clinicopathologic Spectrum of Emerging Kinase Fusion Positive Group of Tumors	7
Gene fusions characterize a subset of uterine cellular leiomyomas	7
Advances in sarcoma molecular diagnostics	7
Clonal dynamics in a composite chronic lymphocytic leukemia and hairy cell leukemia‐variant	7
Molecular investigation of ALK‐rearranged epithelioid fibrous histiocytomas identifies CLTC as a novel fusion partner and evidence of fusion‐independent transcripti	7
Typical, atypical and cryptic t(15;17)(q24;q21) (PML::RARA) observed in acute promyelocytic leukemia: A retrospective review of 831 patients with concurrent chromosome and PML::RARA dual	7
Clinicopathological features and resistance mechanisms in HIP1‐ALK‐rearranged lung cancer: A multicenter study	7
Germline testing for homologous recombination repair genes—opportunities and challenges	7
Molecular analysis of 10 pleomorphic rhabdomyosarcomas reveals potential prognostic markers and druggable targets	7
EWSR1::YY1 fusion positive peritoneal epithelioid mesothelioma harbors mesothelioma epigenetic signature: Report of 3 cases in support of an emerging entity	7
Clinical and genomic characterization of patients diagnosed with the provisional entity acute myeloid leukemia with BCR‐ABL1, a Swedish population‐based study	7
Survey of germline variants in cancer‐associated genes in young adults with colorectal cancer	7