OOIR: Observatory of International Research

Papers

(The TQCC of Genes Chromosomes & Cancer is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Spindle cell neoplasms with novel LTK fusion – Expanding the spectrum of kinase fusion‐positive soft tissue tumors	72
	49
Targeting epigenetic aberrations of sarcoma in CRISPR era	47
Rhabdomyosarcoma With EWSR1::NF2 Gene Fusion: A Case Report Potentially Expanding Its Genetic Spectrum	37
	35
Neonatal osteoblastic tumor with a novel PTBP1::FOSB fusion	34
Rare germline variants in childhood cancer patients suspected of genetic predisposition to cancer	23
An unusual fusion gene EML4‐ALK in a patient with congenital mesoblastic nephroma	22
Issue Information	22
Uncovering variable neoplasms between ATM protein‐truncating and common missense variants using 394 694 UK Biobank exomes	21
Issue Information	21
FGFR1 gene fusions in a subset of pediatric mesenchymal tumors: Expanding the genetic spectrum of tumors sharing histologic overlap with infantile fibrosarcoma and “NTRK<	19
Primary mediastinal large B‐cell lymphoma is characterized by large‐scale copy‐neutral loss of heterozygosity	17
Refined cytogenetic IPSS‐R evaluation by the use of SNP array in a cohort of 290 MDS patients	17
Nanopore DNA Sequencing Detected Chromothripsis‐Induced PAFAH1B1::USP6 Rearrangement in Periosteal Solid Aneurysmal Bone Cyst Initially Diagnosed as Osteosarcoma	16
	16
	16
RUNX1::MIR99AHG Chimera in Acute Myeloid Leukemia	15
Pediatric Fibromatosis Lacks the Internal Tandem Duplication of EGFR Seen in Congenital Mesoblastic Nephroma	15
Design of a targeted next‐generation DNA sequencing panel for pediatric T‐cell lymphoblastic lymphoma to unravel biology and optimize treatment	15
17p13 (TP53) Deletions Are Associated With an Aggressive Phenotype but Unrelated to Patient Prognosis in Urothelial Bladder Carcinomas	15
	14
ERG amplification is a secondary recurrent driver event in myeloid malignancy with complex karyotype and TP53 mutations	14
Recurrent NF1 gene variants and their genotype/phenotype correlations in patients with Neurofibromatosis type I	14
Insertion of an SVA element in MSH2 as a novel cause of Lynch syndrome	14

Clonal origin and genomic diversity in Lynch syndrome‐associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of MLH1 p.L582H	14
The impact of an additional copy of chromosome 21 in B‐cell precursor acute lymphoblastic leukemia	14
Aggressive Spindle Cell Sarcoma in Young Woman With the FGFR1::EBF2 Fusion	14
MYH9::LTK Fusion in a Pediatric Acral Soft Tissue Spindle Cell Neoplasm	13
Issue Information	13
N‐terminus DUX4‐immunohistochemistry is a reliable methodology for the diagnosis of DUX4‐fused B‐lymphoblastic leukemia/lymphoma (N‐terminus DUX4 IHC for DUX4<	12
Molecular analysis of 10 pleomorphic rhabdomyosarcomas reveals potential prognostic markers and druggable targets	12
Constitutional and acquired genetic variants in ARID5B in pediatric B‐cell precursor acute lymphoblastic leukemia	12
A novel HMGA2::KITLG fusion in a dedifferentiated liposarcoma with amplification of MDM2 and HMGA2	12
Fusion‐positive skin/adnexal carcinomas	12
Recurrent VGLL3 fusions define a distinctive subset of spindle cell rhabdomyosarcoma with an indolent clinical course and striking predilection for the head and neck	12
CARMN‐NOTCH2 fusion transcript drives high NOTCH2 expression in glomus tumors of the upper digestive tract	11
Identification of Rare EIF3E::RSPO2 Fusion in Recurrent and Aggressive Urachal Adenocarcinoma	11
Dramatic response to entrectinib in a patient with malignant peripheral nerve sheath tumor harboring novel SNRNP70‐NTRK3 fusion gene	11
Ovarian germ cell tumor/mastocytosis with KIT mutation: A unique clinicopathological entity	11
The novel finding of an FGFR1::TACC1 fusion in an undifferentiated spindle cell sarcoma of soft tissue with aggressive clinical course	11
Low‐grade endometrial stromal sarcoma‐like tumors in male with JAZF1 gene fusions	11
Comprehensive molecular profile of primary cutaneous epithelioid rhabdomyosarcoma: A tumor genomically and molecularly related to malignant melanoma	10
PMS2 or PMS2CL? Characterization of variants detected in the 3′ of the PMS2 gene	10
A Novel ACVR2A::RAF1 Fusion in Spindle Cell Sarcoma	10
TLE3 Is a Novel Fusion Partner of JAK2 in Myeloid/Lymphoid Neoplasm With Eosinophilia Responding to JAK2 Inhibition	10
Pregnancy and the Risk for Cancer in Neurofibromatosis 1	10
Novel ATG7::RAF1 gene fusion in malignant glomus tumor	10
Genetic Heterogeneity in Cellular Angiofibromas	10
Polymorphisms of the PD‐L1 gene 3′‐untranslated region are associated with the expression of PD‐L1 in non‐small cell lung cancer	10
Profiling Precursor microRNAs of Breast Cancer From Total RNA Sequencing Data to Gain Insights Into Their Roles and Prognostic Values	10
Issue Information	10
Advances in sarcoma molecular diagnostics	9
A novel WWTR1::AFF2 fusion in an intra‐abdominal soft tissue sarcoma with associated endometriosis	9
An SS18::NEDD4 cutaneous spindled and epithelioid sarcoma: An hitherto unclassified cutaneous sarcoma, resembling epithelioid sarcoma with aggressive clinical behavior	9
Loss of smarcad1a accelerates tumorigenesis of malignant peripheral nerve sheath tumors in zebrafish	9
Translocation carcinomas of the kidney	9
AXIN2 germline testing in a French cohort validates pathogenic variants as a rare cause of predisposition to colorectal polyposis and cancer	9
Expanding the spectrum of GLI1‐altered mesenchymal tumors—A high‐grade uterine sarcoma harboring a novel PAMR1::GLI1 fusion and literature review of GLI1‐altered mesenchyma	8
Clinicopathologic and survival correlates of embryonal rhabdomyosarcoma driven by RAS/RAF mutations	8
Single nucleotide polymorphism array‐based signature of low hypodiploidy in acute lymphoblastic leukemia	8
GAB1::ABL1 fusions define a distinctive soft tissue neoplasm, with variable perineurial differentiation, and a predilection for children and young adults	8
BRAF V600E and previously unidentified KRAS G12C mutations in odontogenic tumors may affect MAPK activation differently depending on tumor type	8
Erratum	8
Fusion‐positive salivary gland carcinomas	8
Uterine inflammatory myofibroblastic tumor: First report of a ROS1 fusion	7
MDM4 amplification in atypical lipomatous tumors/well‐differentiated liposarcoma: Private event or alternative oncogenic mechanism?	7
Cryptic TCF3 fusions in childhood leukemia: Detection by RNA sequencing	7
Non‐synonymous, synonymous, and non‐coding nucleotide variants contribute to recurrently altered biological processes during retinoblastoma progression	7
Insertion of the CXXC domain of KMT2A into YAP1: An unusual mechanism behind the formation of a chimeric oncogenic protein	7
Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T‐ALL: Focus on miR‐363‐3p and promoter methylation	7
Near complete remission of an inoperable pancreatic acinar cell carcinoma after BRAF‐/MEK‐inhibitor treatment—A case report and review of the literature	7
Sarcomas with sclerotic epithelioid phenotype harboring novel EWSR1‐SSX1 fusions	7
Treatment outcomes and prognosis of patients with primary and acquired BRAF‐mutated non‐small cell lung cancer: A multicenter retrospective study	7
The somatic p.T81dup variant in AKT3 gene underlies a mild cerebral phenotype and expands the spectrum including capillary malformation and lateralized overgrowth	7

Table of Content Volume 60, Number 7, July 2021	7
Standardizing analysis of intra‐tumoral heterogeneity with computational pathology	6
	6
TFG::MET‐rearranged soft tissue tumor: A rare infantile neoplasm with a distinct low‐grade triphasic morphology	6
Issue Information	6
Issue Information	6
	6
Clinicopathological features and resistance mechanisms in HIP1‐ALK‐rearranged lung cancer: A multicenter study	6
Genomic and transcriptomic characterization of desmoplastic small round cell tumors	6
Issue Information	6
EGFR internal tandem duplications in fusion‐negative congenital and neonatal spindle cell tumors	6
A case of spindle cell rhabdomyosarcoma with a ZFP64::NCOA3 fusion	6
Challenging Conventional Perceptions of Oncogenes and Tumor Suppressor Genes: A Comprehensive Analysis of Gene Expression Patterns in Cancer	6
The clinicopathologic significance of NPM1 mutation and ability to detect mutated NPM1 by immunohistochemistry in non‐AML myeloid neoplasms	6
	5
Issue Information	5
NovelHNRNPM::LEUTXfusion resulting from chromothripsis of chromosome 19 in a pediatric undifferentiated small round cell neoplasm	5
Related mechanisms, current treatments, and new perspectives in meningioma	5
Single‐nucleotide polymorphism array and fluorescence in situ hybridization analysis to decode the cytogenetic profile of atypical partial hydatidiform moles diagnosed by short tandem repeat polymorph	5
	5
Amplification of ERBB2 (HER2) in embryonal rhabdomyosarcoma: A potential treatment target in rare cases?	5
Transcriptomic profiles‐based approach to decode the role of miR‐122 in triple negative breast cancer	5
Issue Information	5
	5
Osteoblastoma of the thumb with a novel PRSS44::ALK fusion and literature review of osteoblastoma of hands and feet bones	5
Deciphering epigenetic regulation of enhancers in high‐risk prostate cancer	5
	5
BRAFmutations and concurrent alterations in patients with soft tissue sarcoma	5
A spindle cell neoplasm with MYH9::EGFR fusion and co‐expression of S100 and CD34, further expanding the family of kinase fusion positive spindle cell neoplasms	5
Clinicopathologic and molecular correlates to neoadjuvant chemotherapy‐induced pathologic response in breast angiosarcoma	5
Table of Content Volume 60, Number 6, June 2021	5
Pediatric NCOA3‐rearranged low‐grade fibroblastic tumor with nuclear beta‐catenin immunoreactivity	5