Genes Chromosomes & Cancer

Article	Citations
	63
IGH::IL3‐Rearranged B‐Cell Precursor Acute Lymphoblastic Leukemia With Hypereosinophilia in a Child With a Novel PAX5 Germline Variant	43
Polymorphisms of the PD‐L1 gene 3′‐untranslated region are associated with the expression of PD‐L1 in non‐small cell lung cancer	38
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The Role of RB1 and Secondary Genomic Changes in the Development of Spindle Cell and Pleomorphic Lipomas	25
Neonatal osteoblastic tumor with a novel PTBP1::FOSB fusion	23
Insertion of the CXXC domain of KMT2A into YAP1: An unusual mechanism behind the formation of a chimeric oncogenic protein	21
MDM4 amplification in atypical lipomatous tumors/well‐differentiated liposarcoma: Private event or alternative oncogenic mechanism?	20
Recurrent VGLL3 fusions define a distinctive subset of spindle cell rhabdomyosarcoma with an indolent clinical course and striking predilection for the head and neck	20
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Near complete remission of an inoperable pancreatic acinar cell carcinoma after BRAF‐/MEK‐inhibitor treatment—A case report and review of the literature	17
Comprehensive Analyses of Somatic Copy Number Alterations and Mutations Based on the Adenoma–Carcinoma Sequence	17
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Uterine Myxoid Mesenchymal Tumor With a Novel SS18::VEZF1 Gene Fusion, Lacking Worrisome Histological Features	16
The somatic p.T81dup variant in AKT3 gene underlies a mild cerebral phenotype and expands the spectrum including capillary malformation and lateralized overgrowth	15
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Correction to “Temporal Trends and Regional Variability in BRAF and KRAS Genetic Testing in Denmar	14
Malignant peripheral nerve sheath tumor in children: A clinicopathologic and molecular study with parallels to the adult counterpart	13
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Spindle Cell Rhabdomyosarcoma of Oral Cavity With TCF12::VGLL3 Fusion, Expanding on a Recently Described Entity With Digital Spatial Profiling and Long‐T	13
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Transcript‐Specific DNA Methylation Alterations of the RASSF1	13

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Epithelioid hemangioendothelioma (EHE) with WWTR1::TFE3 gene fusion, a novel fusion variant	13
EWSR1::SSX1 Fusion‐Driven Synovial Sarcoma: A Case Presentation and Review of the Literature	12
VIM::KMT2A‐rearranged sarcomas: A report of two new cases confirming an entity with distinct histologic features	12
Malignant Bone‐Forming Neoplasm With NIPBL::BEND2 Fusion	12
Low‐Level BCR::ABL1 Transcript at Diagnosis in Childhood Leukemia: A 10‐Year Single Institution Study	11
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Expanding the Morphologic and Molecular Spectrum of Spindle Cell Tumors Associated With TERT Fusions	11
Genomic profile analysis of leiomyomas with bizarre nuclei and fumarate hydratase deficient leiomyomas: Strengths, weaknesses, and limitations of array‐CGH interpretation	11
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Novel Resistance Mechanisms to Second‐Generation EGFR Tyrosine Kinase Inhibitor Afatinib and Associations With Genomic Features in	11
GLI1 ‐Altered Mesenchymal Tumor of the Duodenum With a Novel TNFAIP3::GLI1	11
The t(X;5)(q13;q33) Translocation in Myeloid Neoplasms Is Preferentially Associated With Chronic Myelomonocytic Leukemia: A Report From the Groupe Fr	10
Constitutional balanced translocations involving SMARCB1: A rare cause of rhabdoid tumor predisposition syndrome	10
3′RNA and whole‐genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2, HMGA1, or PLAG1	10
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TRAF7 ‐Mutated Fibromyxoid Spindle Cell Tumor of Bone: An Osseous Case Expanding the Spectrum of <	10
A Clinicopathologic and Molecular Reappraisal of Myxoinflammatory Fibroblastic Sarcoma—A Controversial and Pathologically Challenging Low‐Grade Sarcoma	10
Untying the Gordian knot of composite hemangioendothelioma: Discovery of novel fusions	10
Digital pathology systems enabling quality patient care	10
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The presence of a chromosomal abnormality in cytopenia without dysplasia identifies a category of high‐risk clonal cytopenia of unknown significance	10
Structural Variant Analysis of Complex Karyotype Myelodysplastic Neoplasia Through Optical Genome Mapping	10
Novel MIR143HG::PLAG1 gene fusion identified in a rectal myxoid leiomyosarcoma	10
Clear cell mesotheliomas with inactivating VHL mutations and near‐haploid genomic features	10
Issue Information	10
A Bibliometric Analysis on the Risk Factors of Cancer	9
Clinical and Pathologic Description of Three Aneurysmal Bone Cyst Cases With Novel USP6 Fusion Partners Including SEC24D	9
The Variable Genomic Landscape During Osteosarcoma Progression: Insights From a Longitudinal WGS Analysis	9
IDH‐negative chondrosarcoma with metachronous dedifferentiation only in the metastatic site—A diagnostic pitfall	9
Fibromyxoid aSoft Tissue Tumor With PLAG1 Fusion—The First Case in an Adult Patient	9
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Identification of a novel SH3PXD2B::FER fusion in a case of plexiform myofibroblastic tumor and review of the literature	9
Spindle Cell Rhabdomyosarcoma of the Prostate With ZFP64::NCOA2 Fusion	9
Associations of Dietary Intake Traits and Aging Indicators With Colorectal Cancer: A Mendelian Randomization Study	8
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Influence of Cytogenetics on the Outcome of Patients With High‐Risk Myelodysplastic Syndrome Including Deletion 5q Treated With Azacitidine With or Without Lenalidomide	8
Myeloid Neoplasms With a t(5;12)(q31;p13) and an Associated ETV6 :: ACSL6 Gene Fusion Are Diagnostically C	8
Clear Cell Chondrosarcoma With Somatic VHL Inactivation: A Case Report With Integrated Genomic and Transcriptomic Analysis	8
Gene amplification in neoplasia: A cytogenetic survey of 80 131 cases	8
Refined cytogenetic IPSS‐R evaluation by the use of SNP array in a cohort of 290 MDS patients	8
A cloud‐based resource for genome coordinate‐based exploration and large‐scale analysis of chromosome aberrations and gene fusions in cancer	8
A case of a lipoblastoma with EEF1A1::PLAG1 fusion and metaplastic ossification	8
Prevalence and Reclassification of Genetic Variants in South African Populations with Breast Cancer	8
MicroRNA Expression in High‐Grade B‐Cell Lymphoma With 11q Aberration	8
Resurfacing Threats: Metastatic Ossifying Fibromyxoid Tumor Emerging After Almost Two Decades	8
Causative Role for a BRCA2 Germline Pathogenic Variant in External Auditory Canal Squamous Cell Ca	8
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Synovial Sarcoma With BRAF V600E Mutation: A Case Report and Literature Review	8

Identification of Rare EIF3E::RSPO2 Fusion in Recurrent and Aggressive Urachal Adenocarcinoma	7
Rhabdomyosarcoma With EWSR1::NF2 Gene Fusion: A Case Report Potentially Expanding Its Genetic Spec	7
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A New Chapter for Genes, Chromosomes and Cancer	7
Nanopore DNA Sequencing Detected Chromothripsis‐Induced PAFAH1B1::USP6 Rearrangement in Periosteal Solid Aneurysmal Bone Cyst Initially Diagnosed as Osteosarcoma	7
PMS2 or PMS2CL? Characterization of variants detected in the 3′ of the PMS2 gene	7
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Adolescent presentation of FGFR1::EBF2 gene fusion mesenchymal tumor	6
POU2AF3‐rearranged sarcomas: A novel tumor defined by fusions of EWSR1 or FUS to a gene formerly designated COLCA2	6
“Benign” Metastasizing Fibrous Histiocytoma Harboring PRKCD Gene Fusions With Malignant Clinical Course	6
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How to use AI in pathology	6
A novel IRF2BP2::CDX2 Gene fusion in digital intravascular myoepithelioma of soft tissue: An enigma!	6
PLAG1‐Rearranged Fibromyxoid and Lipomatous Neoplasms in Children and Adults: Separate Entities or a Morphological Spectrum?	6
Adult Type Lipoblastoma With a Predominantly Fibroblastic Morphology and a Novel DLEU2::PLAG1 Gene Rearrangement: Two Cases of a Rare Entity	6
Rhabdomyosarcoma With Alveolar Morphology and a Novel NCOA1::ZNF143 Fusion in a 4‐Year‐Old Girl: A Case Report	6
GLI1, CDK4, and MDM2 Co‐Amplification Gastric Plexiform Fibromyxoma: A Case Report and Literature Review	6
Novel ACTB::FER Promoter Swap Fusion Characterizes Rare Superficial Myoid/Myofibroblastic Tumors	6
NovelHNRNPM::LEUTXfusion resulting from chromothripsis of chromosome 19 in a pediatric undifferentiated small round cell neoplasm	6
Malignant Peripheral Nerve Sheath Tumor (MPNST) With Smooth Muscle Differentiation of the Uterus—A Case Report With Emphasis on Diagnostic Pitfalls and Value of DNA Methylation A	5
FIP1L1::PDGFRA Fusion in a Pediatric Patient Presenting With B‐Cell Lymphoblastic Leukemia	5
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Uncovering the WWTR1::NCOA2 Gene fusion in low‐grade myoepithelial‐rich neoplasm with HMGA2 expression: A case report	5
Molecular Landscape of TP53 / RB1 Co‐Altered Tumors Uncovers Emerging Therapeutic Vulnerabilities	5
Germline variation in RASAL2 may predict survival in patients with RAS‐activated colorectal cancer	5
Issue Information	5
Spatial Dynamics of Tumor Cell Plasticity in Lung Adenocarcinoma Revealed by Region‐Specific Single Cell Transcriptomics	5
Intramuscular Myoepithelioma‐Like Hyalinizing Epithelioid Tumor With OGT::FOXO3 Intraexonic DNA Fusion	5
Susanne M. Gollin, PhD, Sept 22, 1953–April 6, 2025	5
TAF15::NR4A3 gene fusion identifies a morphologically distinct subset of extraskeletal myxoid chondrosarcoma mimicking myoepithelial tumors	5
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Calcifying Spindle Cell Soft Tissue Tumor With SOX10::PLAG1 Fusion: A Case Report of a Morphologically Distinctive and Potentially Novel Soft Tissue Tumor	5
Alternative genetic alterations of MYC, BCL2, and/or BCL6 in high‐grade B‐cell lymphoma (HGBL) and diffuse large B‐cell lymphoma (DLBCL): Can we identify dif	5
Durable Response to Pazopanib (Tyrosine Kinase Inhibitor) in a Patient With EWSR1::CREM Gene Fusion Positive Intra‐Abdominal Unclassified Epithelioid Sar	5
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Secondary Genetic Alterations in Extraskeletal Myxoid Chondrosarcoma	5
ALK‐rearranged Mesenchymal Neoplasms: A Report of 9 cases Further Expanding the Clinicopathologic Spectrum of Emerging Kinase Fusion Positive Group of Tumors	5
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Giemsa‐negative chromosome bands preferentially recombine in cancer‐associated translocations and gene fusions	4
Primary Tumor‐Associated Loss of the Y Chromosome and Clinical Outcome in Metastatic Colorectal Cancer	4
Sporadic Breast Angiosarcoma With MYC Amplification on Extrachromosomal Circular DNA Detected Using Nanopore Sequencing in an Adolescent Female	4
Increased MYB alternative promoter usage is associated with relapse in acute lymphoblastic leukemia	4
TFE3‐Altered Perivascular Epithelioid Cell Tumour (PEComa) of the Nasal Cavity With a Novel TRAF3::TFE3 Fusion—A Report of a Case Expanding the Molecular Genetic Spectrum and	4
Successful treatment with MEK‐inhibitor in a patient with NRAS‐related cutaneous skeletal hypophosphatemia syndrome	4
Cell Senescence and the Genetics of Melanoma Development	4
Corrigendum	4
Complete mimicry: Rhabdomyosarcoma with FUS::TFCP2 fusion masquerading as carcinoma—diagnostic challenge and report of two cases	4
Metastasizing aneurysmal dermatofibroma initially diagnosed as angiosarcoma confirmed by CD63::PRKCD fusion gene detection with nanopore sequencing	4
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Clear Cell Tumor With MITF::CREM Fusion: A Rare Case Report of a Newly Described Entity	4
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A cutaneous epithelioid vascular tumor harboring a TPM3::ALK fusion	4
An Affordable and Efficient In‐House Approach for Detecting Gene Fusions in Bone and Soft Tissue Tumors Using a Custom Capture Panel and Nanopore Sequencing	4
MYH9::LTK Fusion in a Pediatric Acral Soft Tissue Spindle Cell Neoplasm	4
GAB1::ABL1 fusions define a distinctive soft tissue neoplasm, with variable perineurial differentiation, and a predilection for children and young adults	3
Expanding the spectrum of GLI1‐altered mesenchymal tumors—A high‐grade uterine sarcoma harboring a novel PAMR1::GLI1 fusion and literature review of GLI1‐altered mesenchyma	3
Correction to “ EWSR1 :: SSX1 Fusion‐Driven Synovial Sarcoma: A Case Presentation and Review of th	3
A Novel MEIS1::NCOA2 Fusion Gene in Acute Myeloid Leukemia	3
Distinct Signatures of Chromosomal Involvement in 59 251 Translocations Across 58 Tumor Types. A Novel Perspective	3
Changes on chromosome 11p15.5 as specific marker for embryonal rhabdomyosarcoma?	3
Spindle cell neoplasms with novel LTK fusion – Expanding the spectrum of kinase fusion‐positive soft tissue tumors	3
EWSR1 Rearrangements in Basaloid Neoplasms With Adnexal Differentiation	3
TFG::MET‐rearranged soft tissue tumor: A rare infantile neoplasm with a distinct low‐grade triphasic morphology	3
Osteoblastoma of the thumb with a novel PRSS44::ALK fusion and literature review of osteoblastoma of hands and feet bones	3
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Novel HMGA2::COL14A1 Fusion Identified in Xanthogranulomatous Epithelial Tumor/Keratin‐Positive Giant Cell Tumor	3
FGFR1 gene fusions in a subset of pediatric mesenchymal tumors: Expanding the genetic spectrum of tumors sharing histologic overlap with infantile fibrosarcoma and “NTRK<	3
A case of spindle cell rhabdomyosarcoma with a ZFP64::NCOA3 fusion	3
The clinicopathologic significance of NPM1 mutation and ability to detect mutated NPM1 by immunohistochemistry in non‐AML myeloid neoplasms	3
A Challenging Case of an Intraosseous Composite Hemangioendothelioma of the Occipital Bone With YAP1::FOXR1 Fusion	3
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BCOR‐Mutated Conventional and Dedifferentiated Chondrosarcoma: A Clinicopathologic Study	2
Cytogenetic and Molecular Analysis of a “Double‐Hit” RUNX1 Including a RUNX1 p.Trp279* and a Cryptic Novel	2
Discovery of Cis‐Regulatory Mechanisms via Non‐Coding Mutations in Acute Lymphoblastic Leukemia	2
A novel colony‐stimulating factor 1 (CSF1) translocation  involving human endogenous retroviral element in a tenosynovial giant cell tumor	2
A case of FN1‐fused calcified chondroid mesenchymal neoplasm of the hand with novel FGFR3 partner gene	2

Detecting Rare ALK Gene Fusions in Unclassified Spindle Cell Lung Tumors Using Anchored Multiplex PCR	2
A Novel JAK2 Fusion in T‐Cell Prolymphocytic Leukemia	2
Shallow whole‐genome sequencing of bone marrow aspirates in myelodysplastic neoplasms: A retrospective comparison with cytogenetics	2
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Genomic profiling of pleomorphic rhabdomyosarcoma reveals a genomic signature distinct from that of embryonal rhabdomyosarcoma	2
Single‐Cell Profiling of Mononuclear Cells Identifies Transcriptomics Signatures Differentiating Prostate Cancer From Benign Prostatic Hyperplasia	2
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Malignant undifferentiated epithelioid neoplasms with MAML2 rearrangements: A clinicopathologic study of seven cases demonstrating a heterogenous entity	2
DICER1‐mutated rhabdomyosarcoma of the ovary with teratoid features	2
Novel EWSR1 :: TEAD3 Fusion in an Adolescen	2
Development and validation of blood tumor mutational burden reference standards	2
Microsatellite Instability and Loss of Heterozygosity as Prognostic Markers in Oral Squamous Cell Carcinoma: Molecular Mechanisms, Detection Techniques, and Therapeutic Strategies	2
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Novel SMARCA4 :: VEZF1 Rearrangement in Pediatric Sarcomas	2
A novel STRN3::PRKD1 fusion in a cribriform adenocarcinoma of salivary gland with high‐grade transformation	2
Pseudoglandular Schwannoma With FUS::KLF17 Fusion: Broadening the Spectrum of FUS‐Associated Tumors	2
Characterization of Pediatric Acute Myeloid Leukemia With t(7;12)(q36;p13)	2
Vanished MDM2 amplification in multiple recurrences of an irradiated poorly differentiated sarcoma with amplified TRIO::TERT fusion gene	2
Novel PDGFRB Gene Fusions in Two Cases of Infantile Myofibromatosis	1
Rethinking cancer initiation: The role of large‐scale mutational events	1
A Novel Targeted Sequence for Chromosome 11p15.5 Maternal Loss in SDHD ‐Related Paragangliomas	1
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NR1D1::MAML1 epithelioid and spindle cell sarcoma mimicking pseudomyogenic hemangioendothelioma in core biopsy: A case report and review of the literature	1
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Molecular Classification of Resected Primary Duodenal Adenocarcinoma	1
Widening the Spectrum of Fusion Events in Schwannoma: Identification of a Novel TANC1::HTRA1 Fusion	1
Macroscopic Monozygotic Androgenetic/Biparental Mosaicism: Molecular Characterization and Clinical Implications	1
Novel Fusion Gene Transcripts and Targetable Mutations in High‐Risk B‐ ALL With Exceptional Response to Venetoclax‐Based Therapy	1
An Inflammatory Myofibroblastic Tumor With a Novel ALKV1180L Mutation Leading to Acquired Resistance to Tyrosine Kinase Inhibitors	1
Constitutional and acquired genetic variants in ARID5B in pediatric B‐cell precursor acute lymphoblastic leukemia	1
A novel t(X;21)(p11.4;q22.12) translocation adds to the role of BCOR and RUNX1 in myelodysplastic syndromes and acute myeloid leukemias	1
Pediatric Fibromatosis Lacks the Internal Tandem Duplication of EGFR Seen in Congenital Mesoblastic Nephroma	1
Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture‐Based Gene Panel	1
The Transcriptomic and Gene Fusion Landscape of Pleomorphic Salivary Gland Adenomas	1
High‐Grade Uterine Sarcoma: First Report of a MEIS2::FOXO4 Fusion	1
Spindle Cell Sarcoma With Novel JAZF1::NUDT5 Gene Fusion: Report of a Previously Undescribed Neopl	1
Challenging Conventional Perceptions of Oncogenes and Tumor Suppressor Genes: A Comprehensive Analysis of Gene Expression Patterns in Cancer	1
Hereditary Colorectal Cancer and Polyposis Syndromes Caused by Variants in Uncommon Genes	1
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Biallelic NF1 Inactivation and Widespread Loss of Heterozygosity in a Subset of Unclassified Fibro	1
Gene Expression Profiles of AHNAK2, DCSTAMP, FN1, and TERT Correlate With Mutational Status and Recurrence in Papillary Thyroid Carcinoma	1
When molecular outsmarts morphology: Malignant ossifying fibromyxoid tumors masquerading as osteosarcomas, including a novel CREBZF::PHF1 fusion	1
NF1 Mutated Gastrointestinal Stromal Tumors With Coamplification of	1
Novel SMARCA2 :: DDIT3	1
Biphenotypic Sinonasal Sarcoma With a Novel PAX3::MAML2 Fusion	1
17p13 (TP53) Deletions Are Associated With an Aggressive Phenotype but Unrelated to Patient Prognosis in Urothelial Bladder Carcinomas	1
Standardizing analysis of intra‐tumoral heterogeneity with computational pathology	1
Clinicopathologic and molecular correlates to neoadjuvant chemotherapy‐induced pathologic response in breast angiosarcoma	1
Profiling Precursor microRNAs of Breast Cancer From Total RNA Sequencing Data to Gain Insights Into Their Roles and Prognostic Values	1
Novel MED15::ATF1 fusion in a pediatric melanoma with spitzoid features and aggressive presentation	1
Segregation, immunohistochemical, molecular and functional analyses classify a novel missense variant in fumarate hydratase (FH) as pathogenic	1
Extrachromosomal DNA Detection and Ultrastructural Profiling in Lung and Colorectal Cancer Models	1
A novel HMGA2::KITLG fusion in a dedifferentiated liposarcoma with amplification of MDM2 and HMGA2	1
Comprehensive RNA Sequencing Analysis Reveals Heterogeneous Expression of Epstein–Barr Virus Genes in Gastric Cancer	1
Clonal origin and genomic diversity in Lynch syndrome‐associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of MLH1 p.L582H	1
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Complementary value of molecular analysis to expert review in refining classification of uncommon soft tissue tumors	1
Comparative DNA Methylation Profiling of Human and Murine ALK‐Positive B‐Cell Neoplasms	1
Schwann Cells Deficient in Neurofibromin Lack Sensitivity to Their Biomechanical Microenvironment	1
COL1A1::PDGFB fusion uterine sarcoma with a TERT promoter mutation	1
An intraosseous myoepithelial carcinoma with a EWSR1::PBX3 fusion	1