OOIR: Observatory of International Research

Papers

(The median citation count of Biologicals is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
EGF domain peptide of Developmentally regulated endothelial locus1 facilitates gene expression of extracellularly applied plasmid DNA	19
Aims and Scope/Editorial Board/Publishing Details	18
Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Reports from a series of NC3Rs stakeholder workshops	12
Rationale for supporting stepwise access to safe plasma proteins through local production in low- and middle-income countries: A commentary of an international workshop	11
The development and establishment of a heat inactivated preparation of Mycobacterium tuberculosis (H37Rv) as the first international standard for nucleic acid amplification techniques	10
A validated polyclonal antiserum-based immunoassay for assessment of HPV 16 L1 relative potency	9
Production and characterization of monoclonal antibodies against hepatitis B e-antigen and their potential application for development of HBeAg detection ELISA	9
Outer membrane vesicles as nanovaccine candidates against pathogenic Leptospira in experimental Guinea pig model	9
Potential therapeutic effects of hAMSCs secretome on Panc1 pancreatic cancer cells through downregulation of SgK269, E-cadherin, vimentin, and snail expression	9
Glycosylation differences of an anti-VEGF monoclonal antibody (PRO-169) and its extensive comparison with Bevacizumab	8
Aims and Scope/Editorial Board/Publishing Details	8
Global availability of critical reagents for biologicals testing - Current status, challenges and possible solutions	8
Nanoparticle formulation for the development of a dog nanovaccine against Cystic Echinococcosis	8
A species-independent indirect-ELISA for detection of antibodies to the non-structural protein 2B of foot-and-mouth disease virus	8
Animal cell substrates for the production of biologicals: An introduction to WHO documents	7
Regulatory workshop on challenge strain development and GMP manufacture – A stakeholder meeting report	7
The future of pyrogenicity testing: Phasing out the rabbit pyrogen test. A meeting report	7
Validation of a next generation sequencing method for adventitious virus detection: Demonstration of sensitivity in multiple cell lines	7
Replacement of in vivo leptospirosis vaccine potency testing in the United States	6
Evaluation of candidate International Standards for meningococcal capsular polysaccharide groups W and Y	6
Detection of hepatitis C virus and parvovirus B19 in human plasma pools by nucleic-acid amplification techniques – Trends in results of EDQM proficiency testing studies from 2004 to 2018	6
Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals	6
IABS/DCVMN webinar on next generation sequencing	6
Ethical approval for controlled human infectious model clinical trial protocols – A workshop report	6
Nano-emulsion encapsulation for the efficient delivery of bacteriophage therapeutics	6

Collaborative study for the calibration of a replacement International Standard for Diphtheria Antitoxin Equine	5
Evaluation of the focus reduction neutralization and ELISA tests compared to the plaque reduction neutralization test for the detection of antibodies against measles virus	5
A rapid and simple sterility test method based on solid culture medium containing blood	5
In silico discovery of epitopes of gag and env proteins for the development of a multi-epitope vaccine candidate against Maedi Visna Virus using reverse vaccinology approach	5
Accelerating Global Deletion of the Abnormal Toxicity Test for vaccines and biologicals. Planning common next steps. A workshop Report	5
Glycoconjugation of Shigella flexneri type 2a O-polysaccharide with CRM197 as a potential vaccine candidate for shigellosis	5
Mass spectrometry analysis of bovine tuberculins - 3R potential in batch potency testing	4
Development and comparison of three cell-based potency assays for anti-respiratory syncytial virus monoclonal antibody	4
Expression profiling of inflammation-related genes including IFI-16, NOTCH2, CXCL8, THBS1 in COVID-19 patients	4
An adventitious agent-free clonal cell line that is highly susceptible to foot -and-mouth disease virus	4
Development and evaluation of an external quality control and internal quality control containing real-time RT-PCR assay for the detection of o'nyong-nyong virus	4
IABS/CEPI platform technology webinar: Is it possible to reduce the vaccine development time?	4
Novel vaccine candidates of Bordetella pertussis identified by reverse vaccinology	4
Aims and Scope/Editorial Board/Publishing Details	4
Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay	3
Animal experiments show impact of vaccination on reduction of SARS-CoV-2 virus circulation: A model for vaccine development?	3
Maintaining the quality of vaccines through the use of standards: Current challenges and future opportunities	3
The role of real-world evidence for regulatory and public health decision-making for Accelerated Vaccine Deployment- a meeting report	3
Enabling the evaluation of COVID-19 vaccines with correlates of protection	3
Aims and Scope/Editorial Board/Publishing Details	3
Report for the Eighth Asian National Control Laboratory Network meeting in 2023: Self-sufficiency strategy of plasma-derived medicinal products and regulatory harmonisation	3
Designing multi-epitope vaccine against human cytomegalovirus integrating pan-genome and reverse vaccinology pipelines	3
Aims and Scope/Editorial Board/Publishing Details	3
Future of TABST and LABST in the Indian Pharmacopoeia Monographs A Humane Society International/India Workshop Report	3
Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Responses from a survey of National Control Laboratories and National Regulatory Authorities	3
Aims and Scope/Editorial Board/Publishing Details	3
Risk assessment for biopharmaceutical single-use manufacturing: A case study of upstream continuous processing	3
Prevalence of viral agents causing swine reproductive failure in Korea and the development of multiplex real-time PCR and RT-PCR assays	3
Aims and Scope/Editorial Board/Publishing Details	3
Assessment of the risks associated with the use of in vivo versus in vitro potency tests for vaccines	3
Glycoconjugate content quantification to assess vaccine potency: A simplified approach	3
From eradication to re-emergence: The changing landscape of polio in the cVDPV2 era	3
Obituary - Inessa LEVENBOOK: 1926–2022	3
Evolution of FMT – From early clinical to standardized treatments	3
Advances in mRNA vaccine research in the field of quality control	2
An optimized microplate-based method to evaluate complement-dependent hemolysis mediated by intravenous immunoglobulins (IVIG)	2
A practical approach for gmp-compliant validation of real-time PCR method for mycoplasma detection in human mesenchymal stromal cells as advanced therapy medicinal product	2
Regulatory perspective for quality evaluation of lipid nanoparticle-based mRNA vaccines in China	2
Klebsiella pneumoniae vaccine studies in animal models	2
Expression and purification of Hepatitis B virus core antigen using Escherichia coli and its utilization for the diagnosis of Hepatitis B virus infections	2
Viral clearance capability of monoclonal antibody purification	2
Virus filtration using small pore virus filter in downstream processing of biotherapeutic products: The effect of operating pressure	2
Collaborative study on the cross-reactivity of two influenza B viral components in single radial immunodiffusion assay using quadrivalent influenza vaccines in Japan from 2015/16 to 2021–22 influenza	2
Adjuvant effect of mesoporous silica SBA-15 on anti-diphtheria and anti-tetanus humoral immune response	2
The current status of the biosimilars landscape in China	2
A vision for patient-centric specifications for biologicals	2
Development of an optimized RT-LAMP test for the detection of SARS-CoV-2	2
Autogenous vaccines: Quality of production and movement in a common market	2
Accelerated national lot release on COVID-19 vaccines in Republic of Korea	2
WHO informal consultation on revision of guidelines on evaluation of similar biotherapeutic products, virtual meeting, 30 June – 2 July 2021	2

Aims and Scope/Editorial Board/Publishing Details	2
Corrigendum to “Multiple factors shape technology transfer for the development and manufacture of vaccines in Latin America and the Caribbean” [Biologicals 90 (2025) 101826]	2
Aims and Scope/Editorial Board/Publishing Details	2
Similarity demonstrated between isolated charge variants of MB02, a biosimilar of bevacizumab, and Avastin® following extended physicochemical and functional characterization	2
Design and computational evaluation of a novel multi-epitope hybrid vaccine against monkeypox virus: Potential targets and immunogenicity assessment for pandemic preparedness	2
Identification of contaminating mollicutes in mammalian cell culture as spiroplasma species	2
Development and evaluation of recombinant gD protein based ELISA for sero-surveillance of BoHV-1 in India	2
Immunization effect of lipopolysaccharide antigen in conjugation with PLGA nanoparticles as a nanovaccine against Brucella melitensis infection	2
Evaluation of DF-1 cell culture based vaccine development for infectious bursal disease virus in Ethiopia	2
Multiple factors shape technology transfer for the development and manufacture of vaccines in Latin America and the Caribbean	1
Expression, purification, and immunogenicity study of human papillomavirus type 52 virus-like particles produced in Hansenula polymorpha	1
Zoonoses Anticipation and Preparedness Initiative, stakeholders conference, February 4 & 5, 2021	1
Infectivity assessment of porcine endogenous retrovirus using high-throughput sequencing technologies	1
An indirect ELISA for detecting anti-SARS-CoV-2 antibodies in human sera using a baculovirus-expressed recombinant nucleocapsid antigen	1
Regulatory changes during the Covid-19 pandemic: A comparative review of the European Union and Brazilian regulations for biological and biotechnological products	1
Aims and Scope/Editorial Board/Publishing Details	1
Report on the GHPP-BloodTrain online workshop on “Authorisation and Licensing of Blood Establishments - Review of quality documentation of blood and blood components”, 5th-8th of July 2021	1
Efficient extraction of adventitious virus nucleic acid using commercially available methods	1
Overview of regulatory frameworks on the national lot release of plasma-derived medicinal products in Korea	1
An alternative In vitro method for evaluation of inactivated infectious bronchitis (IB) vaccines	1
Development and optimization of multiplex PCR for rapid detection of type I-F1 and type I-F2 Cas cluster genes in Acinetobacter baumannii	1
A gaps-and-needs analysis of vaccine R&D in Europe: Recommendations to improve the research infrastructure	1
Canine parvovirus type 2 vaccines in Brazil: Viral load in commercial vaccine vials and phylogenetic analysis of the vaccine viruses	1
Emerging genetic diversity of SARS-CoV-2 RNA dependent RNA polymerase (RdRp) alters its B-cell epitopes	1
Development and characterization of mouse monoclonal antibodies to canine morbillivirus	1
A collaborative study to establish the second national standard for antithrombin concentrate in Korea	1
Report on the seventh meeting of national control laboratories for vaccines and biologicals of the WHO Western Pacific and South-East Asia member states	1
Adjuvant effects of novel water/oil emulsion formulations on immune responses against infectious bronchitis (IB) vaccine in mice	1
Aims and Scope/Editorial Board/Publishing Details	1
Molecular characterization of Anaplasma ovis Msp4 protein in strains isolated from ticks in Turkey: A multi-epitope synthetic vaccine antigen design against Anaplasma ovis using immunoinformatic tools	1
Aims and Scope/Editorial Board/Publishing Details	1
Antivenoms, hepatitis B vaccine and oral polio vaccine can be considered for storage and handling outside the cold chain following the innovative ‘controlled temperature chain’ approach	1
Aims and Scope/Editorial Board/Publishing Details	1