OOIR: Observatory of International Research

Papers

(The median citation count of Molecular and Cellular Neuroscience is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Operative list of genes associated with autism and neurodevelopmental disorders based on database review	67
Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models	36
Mechanotransduction in mammalian sensory hair cells	30
Regulation of actin dynamics in dendritic spines: Nanostructure, molecular mobility, and signaling mechanisms	27
Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine	25
Molecular correlates of mitochondrial dysfunctions in major depression: Evidence from clinical and rodent studies	25
Macrophage roles in peripheral nervous system injury and pathology: Allies in neuromuscular junction recovery	25
Sulfatide in health and disease. The evaluation of sulfatide in cerebrospinal fluid as a possible biomarker for neurodegeneration	21
Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells	20
LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease	20
Neuroprotection with the cannabigerol quinone derivative VCE-003.2 and its analogs CBGA-Q and CBGA-Q-Salt in Parkinson's disease using 6-hydroxydopamine-lesioned mice	19
Elevated soluble amyloid beta protofibrils in Down syndrome and Alzheimer's disease	19
The dietary fatty acids α-linolenic acid (ALA) and linoleic acid (LA) selectively inhibit microglial nitric oxide production	18
When glia meet induced pluripotent stem cells (iPSCs)	17
Pharmacologic treatments in preclinical tinnitus models with special focus on Ginkgo biloba leaf extract EGb 761®	16
The role of E3 ubiquitin ligases in synapse function in the healthy and diseased brain	16
Presynaptic voltage-gated calcium channels in the auditory brainstem	15
Ketamine attenuates the PTSD-like effect via regulation of glutamatergic signaling in the nucleus accumbens of mice	15
Animal models of hidden hearing loss: Does auditory-nerve-fiber loss cause real-world listening difficulties?	15
Axonal spheroids in neurodegeneration	15
Revealing NOTCH-dependencies in synaptic targets associated with Alzheimer's disease	15
Polyglutamine expanded Ataxin-7 induces DNA damage and alters FUS localization and function	14
Erythropoietin modulates striatal antioxidant signalling to reduce neurodegeneration in a toxicant model of Parkinson's disease	14
Identifying targets to prevent aminoglycoside ototoxicity	14
Intermitochondrial signaling regulates the uniform distribution of stationary mitochondria in axons	14

Nectins and Nectin-like molecules in synapse formation and involvement in neurological diseases	14
Synaptic transmission at the vestibular hair cells of amniotes	13
Dimethyl itaconate reprograms neurotoxic to neuroprotective primary astrocytes through the regulation of NLRP3 inflammasome and NRF2/HO-1 pathways	13
Long-term exposure to GDNF induces dephosphorylation of Ret, AKT, and ERK1/2, and is ineffective at protecting midbrain dopaminergic neurons in cellular models of Parkinson's disease	13
The potential roles of excitatory-inhibitory imbalances and the repressor element-1 silencing transcription factor in aging and aging-associated diseases	13
Mitochondrial and autophagy-lysosomal pathway polygenic risk scores predict Parkinson's disease	13
Opioid receptor activation suppresses the neuroinflammatory response by promoting microglial M2 polarization	12
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE)	12
BDNF-modified human umbilical cord mesenchymal stem cells-derived dopaminergic-like neurons improve rotation behavior of Parkinson's disease rats through neuroprotection and anti-neuroinflammation	11
Plasticity of postsynaptic nanostructure	11
Glutamine metabolism in diseases associated with mitochondrial dysfunction	11
Amyloid-β precursor protein processing and oxidative stress are altered in human iPSC-derived neuron and astrocyte co-cultures carrying presenillin-1 gene mutations following spontaneous differentiati	10
Parvalbumin subtypes of cerebellar Purkinje cells contribute to differential intrinsic firing properties	10
Logistics of neuronal protein turnover: Numbers and mechanisms	10
Postganglionic sympathetic neurons, but not locus coeruleus optostimulation, activates neuromuscular transmission in the adult mouse in vivo	10
Resilience to fear: The role of individual factors in amygdala response to stressors	10
microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice	10
Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration	10
Artesunate restores the levels of inhibitory synapse proteins and reduces amyloid-β and C-terminal fragments (CTFs) of the amyloid precursor protein in an AD-mouse model	10
Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence	9
Effect of germ-free status on transcriptional profiles in the nucleus accumbens and transcriptomic response to chronic morphine	9
Behavioral profiling reveals an enhancement of dentate gyrus paired pulse inhibition in a rat model of PTSD	9
The relevance of synuclein autoantibodies as a biomarker for Parkinson's disease	9
Memantine improves cognitive deficits via KATP channel inhibition in olfactory bulbectomized mice	8
Endogenous Aβ peptide promote Aβ oligomerization tendency of spiked synthetic Aβ in Alzheimer's disease plasma	8
Blockade of metabotropic glutamate receptor 5 attenuates axonal degeneration in 6-hydroxydopamine-induced model of Parkinson's disease	8
Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2	8
CHRNA1 promotes the pathogenesis of primary focal hyperhidrosis	8
Taurine inhibits KDM3a production and microglia activation in lipopolysaccharide-treated mice and BV-2 cells	8
Transcriptional and epigenetic regulation of microglia in substance use disorders	8
Enduring neuroimmunological consequences of developmental experiences: From vulnerability to resilience	8
An integrative study of genetic variants with brain tissue expression identifies viral etiology and potential drug targets of multiple sclerosis	8
In vitro and in vivo models: What have we learnt about inner ear regeneration and treatment for hearing loss?	8
Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons	8
Neuronal endoplasmic reticulum architecture and roles in axonal physiology	7
Long-term taurine administration improves motor skills in a tubulinopathy rat model by decreasing oxidative stress and promoting myelination	7
Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice	7
Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes	7
Loss of POGZ alters neural differentiation of human embryonic stem cells	7
Cytoplasmic TDP-43 accumulation drives changes in C-bouton number and size in a mouse model of sporadic Amyotrophic Lateral Sclerosis	7
Cardiolipin released by microglia can act on neighboring glial cells to facilitate the uptake of amyloid-β (1–42)	7
GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease	7
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells	7
Methylation at a conserved lysine residue modulates tau assembly and cellular functions	7
The Tardigrade damage suppressor protein Dsup promotes DNA damage in neurons	7
Functions of the tubulin code in the C. elegans nervous system	6
In vivo neuroplasticity in vestibular animal models	6
Differential expression of glutamatergic receptor subunits in the hippocampus in carioca high- and low-conditioned freezing rats	6
Inhibitory signaling in mammalian olfactory transduction potentially mediated by Gαo	6
IRS1 expression in hippocampus is age-dependent and is required for mature spine maintenance and neuritogenesis	6

Inhibitory mechanism of an antifungal drug, caspofungin against amyloid β peptide aggregation: Repurposing via neuroinformatics and an experimental approach	6
Kv1.1 subunits localize to cardiorespiratory brain networks in mice where their absence induces astrogliosis and microgliosis	6
Hepcidin inhibits autophagy in intracerebral hemorrhage models in vitro and in vivo	6
Signatures of cochlear processing in neuronal coding of auditory information	6
In vitro priming response in dorsal root ganglia partially mimics injury-driven pre-conditioning response and reprograms neurons for enhanced outgrowth	5
Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3	5
Altered hippocampal dendritic spine maturation after hypoxia-induced seizures in neonatal rats	5
The amyotrophic lateral sclerosis-linked protein TDP-43 regulates interleukin-6 cytokine production by human brain pericytes	5
Interleukin-15 modulates the response of cortical neurons to ischemia	5
Correcting a widespread error: Neuroprotectant N-acetyl-L-tryptophan does not bind to the neurokinin-1 receptor	5
Chemogenetic inhibition of TrkB signalling reduces phrenic motor neuron survival and size	5
DNA repair pathways are altered in neural cell models of frataxin deficiency	5
Differential expression of serotonin2B receptors in GABAergic and serotoninergic neurons of the rat and mouse dorsal raphe nucleus	5
The function of FUS in neurodevelopment revealed by the brain and spinal cord organoids	5
Comparing effects of microgravity and amyotrophic lateral sclerosis in the mouse ventral lumbar spinal cord	5
GDNF requires HIF-1α and RET activation for suppression of programmed cell death of enteric neurons by metabolic challenge	5
Golgi stress induces upregulation of the ER-Golgi SNARE Syntaxin-5, altered βAPP processing, and Caspase-3-dependent apoptosis in NG108-15 cells	5
Identification of novel Aβ-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease	5
Contributions of microtubule dynamics and transport to presynaptic and postsynaptic functions	5
Identification of cytoskeletal proteins as binding partners of Bri2 BRICHOS domain	5
Systemic inflammation induced from remote extremity trauma is a critical driver of secondary brain injury	5
GPR3 accelerates neurite outgrowth and neuronal polarity formation via PI3 kinase-mediating signaling pathway in cultured primary neurons	5
The identification of PSEN1 p.Tyr159Ser mutation in a non-canonic early-onset Alzheimer's disease family	5
The interaction between intestinal bacterial metabolites and phosphatase and tensin homolog in autism spectrum disorder	5
Molecular mechanisms of AMPAR reversible stabilization at synapses	5
Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus	5
Depletion of regulatory T cells exacerbates inflammatory responses after chronic cerebral hypoperfusion in mice	4
Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment	4
Unexpected role of stress as a possible resilience mechanism upon mild traumatic brain injury (mTBI) in mice	4
Inactivation of vimentin in satellite glial cells affects dorsal root ganglion intermediate filament expression and neuronal axon growth in vitro	4
The elastin-derived peptide (VGVAPG) activates autophagy in neuroblastoma (SH-SY5Y) cells via peroxisome proliferator-activated receptor gamma (PPARγ)	4
Methods for multiscale structural and functional analysis of the mammalian cochlea	4
Deletion of PTEN in microglia ameliorates chronic neuroinflammation following repetitive mTBI	4
Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1	4
Computational insights into mRNA and protein dynamics underlying synaptic plasticity rules	4
Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease	4
Harmonic viscoelastic response of 3D histology-informed white matter model	4
Skeletal muscle sympathetic denervation disrupts the neuromuscular junction postterminal organization: A single-cell quantitative approach	4
The AICD fragment of APP initiates a FoxO3a mediated response via FANCD2	3
Characterization hiPSC-derived neural progenitor cells and neurons to investigate the role of NOS1AP isoforms in human neuron dendritogenesis	3
Pregabalin-induced neuroprotection and gait improvement in dystrophic MDX mice	3
Turnover of synaptic adhesion molecules	3
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation	3
Early life adversity: Epigenetic regulation underlying drug addiction susceptibility	3
Emerging roles of PHLPP phosphatases in the nervous system	3
VPS35 deficiency in the embryonic cortex leads to prenatal cell loss and abnormal development of axonal connectivity	3
Sex differences in susceptibility to substance use disorder: Role for X chromosome inactivation and escape?	3
SMN loss dysregulates microtubule-associated proteins in spinal muscular atrophy model	3
Immunomodulatory protein from ganoderma microsporum protects against oxidative damages and cognitive impairments after traumatic brain injury	3
Epigenomic profiling of mouse nucleus accumbens at single-cell resolution	3
Bilirubin induces microglial NLRP3 inflammasome activation in vitro and in vivo	3
Alpha-synuclein negatively controls cell proliferation in dopaminergic neurons	3
Paternal morphine exposure in rats reduces social play in adolescent male progeny without affecting drug-taking behavior in juvenile males or female offspring	3
Circular RNA regulation and function in drug seeking phenotypes	3
Defective Reelin/Dab1 signaling pathways associated with disturbed hippocampus development of homozygous yotari mice	3
Possible involvement of progranulin in the protective effect of elastase inhibitor on cerebral ischemic injuries of neuronal and glial cells	3
Phenelzine-based probes reveal Secernin-3 is involved in thermal nociception	3
The transcriptional response to acute cocaine is inverted in male mice with a history of cocaine self-administration and withdrawal throughout the mesocorticolimbic system	3