OOIR: Observatory of International Research

Papers

(The median citation count of Molecular and Cellular Neuroscience is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells	163
Operative list of genes associated with autism and neurodevelopmental disorders based on database review	48
Models of the blood-brain barrier using iPSC-derived cells	42
Norepinephrine and glucocorticoid effects on the brain mechanisms underlying memory accuracy and generalization	41
Tcf4 is required for correct brain development during embryogenesis	34
Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures	31
Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models	28
The impact of chronic stress on energy metabolism	27
Macrophage roles in peripheral nervous system injury and pathology: Allies in neuromuscular junction recovery	24
Regulation of actin dynamics in dendritic spines: Nanostructure, molecular mobility, and signaling mechanisms	24
Molecular mechanisms of cell polarity in a range of model systems and in migrating neurons	23
Δ9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons	23
Mechanotransduction in mammalian sensory hair cells	21
Spatial control of membrane traffic in neuronal dendrites	21
Smart motors and cargo steering drive kinesin-mediated selective transport	21
Activation and functional modulation of satellite glial cells by oxaliplatin lead to hyperexcitability of sensory neurons in vitro	21
Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells	19
Molecular correlates of mitochondrial dysfunctions in major depression: Evidence from clinical and rodent studies	19
ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation	18
P38K and JNK pathways are induced by amyloid-β in astrocyte: Implication of MAPK pathways in astrogliosis in Alzheimer's disease	18
Sulfatide in health and disease. The evaluation of sulfatide in cerebrospinal fluid as a possible biomarker for neurodegeneration	16
Neuroprotection with the cannabigerol quinone derivative VCE-003.2 and its analogs CBGA-Q and CBGA-Q-Salt in Parkinson's disease using 6-hydroxydopamine-lesioned mice	16
Leptin stimulates synaptogenesis in hippocampal neurons via KLF4 and SOCS3 inhibition of STAT3 signaling	16
Human pluripotent stem cells: A toolbox to understand and treat retinal degeneration	15
The ubiquitin ligase UBE4B regulates amyloid precursor protein ubiquitination, endosomal trafficking, and amyloid β42 generation and secretion	15

Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons	15
Mitochondrial damage-associated molecular patterns stimulate reactive oxygen species production in human microglia	15
When glia meet induced pluripotent stem cells (iPSCs)	14
Elevated soluble amyloid beta protofibrils in Down syndrome and Alzheimer's disease	14
Erythropoietin modulates striatal antioxidant signalling to reduce neurodegeneration in a toxicant model of Parkinson's disease	14
LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease	14
Overexpression of the vesicular acetylcholine transporter disrupts cognitive performance and causes age-dependent locomotion decline in Drosophila	13
Animal models of hidden hearing loss: Does auditory-nerve-fiber loss cause real-world listening difficulties?	13
The dietary fatty acids α-linolenic acid (ALA) and linoleic acid (LA) selectively inhibit microglial nitric oxide production	13
Polyglutamine expanded Ataxin-7 induces DNA damage and alters FUS localization and function	13
Application of induced pluripotent stem cells in epilepsy	13
The role of E3 ubiquitin ligases in synapse function in the healthy and diseased brain	12
Pharmacologic treatments in preclinical tinnitus models with special focus on Ginkgo biloba leaf extract EGb 761®	12
The potential roles of excitatory-inhibitory imbalances and the repressor element-1 silencing transcription factor in aging and aging-associated diseases	12
Effects of selective inhibition of nNOS and iNOS on neuropathic pain in rats	12
Ketamine attenuates the PTSD-like effect via regulation of glutamatergic signaling in the nucleus accumbens of mice	12
Cyclic regulation of Trpm4 expression in female vomeronasal neurons driven by ovarian sex hormones	11
Nectins and Nectin-like molecules in synapse formation and involvement in neurological diseases	11
Synaptic transmission at the vestibular hair cells of amniotes	11
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE)	10
Identifying targets to prevent aminoglycoside ototoxicity	10
Axonal spheroids in neurodegeneration	10
Presynaptic voltage-gated calcium channels in the auditory brainstem	10
Opioid receptor activation suppresses the neuroinflammatory response by promoting microglial M2 polarization	10
Revealing NOTCH-dependencies in synaptic targets associated with Alzheimer's disease	10
Dimethyl itaconate reprograms neurotoxic to neuroprotective primary astrocytes through the regulation of NLRP3 inflammasome and NRF2/HO-1 pathways	9
Intermitochondrial signaling regulates the uniform distribution of stationary mitochondria in axons	9
Artesunate restores the levels of inhibitory synapse proteins and reduces amyloid-β and C-terminal fragments (CTFs) of the amyloid precursor protein in an AD-mouse model	9
Mitochondrial and autophagy-lysosomal pathway polygenic risk scores predict Parkinson's disease	9
Postganglionic sympathetic neurons, but not locus coeruleus optostimulation, activates neuromuscular transmission in the adult mouse in vivo	9
ALS, a cellular whodunit on motor neuron degeneration	9
The corepressor CtBP2 is required for proper development of the mouse cerebral cortex	9
Parvalbumin subtypes of cerebellar Purkinje cells contribute to differential intrinsic firing properties	9
Autophagy modulates Aβ accumulation and formation of aggregates in yeast	9
Long-term exposure to GDNF induces dephosphorylation of Ret, AKT, and ERK1/2, and is ineffective at protecting midbrain dopaminergic neurons in cellular models of Parkinson's disease	9
Sympathomimetics regulate quantal acetylcholine release at neuromuscular junctions through various types of adrenoreceptors	8
Memantine improves cognitive deficits via KATP channel inhibition in olfactory bulbectomized mice	8
Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR	8
Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics	8
Ih, GIRK, and KCNQ/Kv7 channels differently modulate sharp wave - ripples in the dorsal and ventral hippocampus	8
Resilience to fear: The role of individual factors in amygdala response to stressors	8
CHRNA1 promotes the pathogenesis of primary focal hyperhidrosis	8
Blockade of metabotropic glutamate receptor 5 attenuates axonal degeneration in 6-hydroxydopamine-induced model of Parkinson's disease	8
Amyloid-β precursor protein processing and oxidative stress are altered in human iPSC-derived neuron and astrocyte co-cultures carrying presenillin-1 gene mutations following spontaneous differentiati	8
The relevance of synuclein autoantibodies as a biomarker for Parkinson's disease	8
Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration	8
BDNF-modified human umbilical cord mesenchymal stem cells-derived dopaminergic-like neurons improve rotation behavior of Parkinson's disease rats through neuroprotection and anti-neuroinflammation	8
Enduring neuroimmunological consequences of developmental experiences: From vulnerability to resilience	7
An integrative study of genetic variants with brain tissue expression identifies viral etiology and potential drug targets of multiple sclerosis	7
Behavioral profiling reveals an enhancement of dentate gyrus paired pulse inhibition in a rat model of PTSD	7

Identification of MAGUK scaffold proteins as intracellular binding partners of synaptic adhesion protein Slitrk2	7
Pharmacological inhibition of sphingosine-1-phosphate lyase partially reverses spatial memory impairment in streptozotocin-diabetic rats	7
Endogenous Aβ peptide promote Aβ oligomerization tendency of spiked synthetic Aβ in Alzheimer's disease plasma	7
Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine	7
Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons	7
Role of induced pluripotent stem cells in lysosomal storage diseases	7
In vitro and in vivo models: What have we learnt about inner ear regeneration and treatment for hearing loss?	7
Long-term taurine administration improves motor skills in a tubulinopathy rat model by decreasing oxidative stress and promoting myelination	6
Molecular dissection of TNFR-TNFα bidirectional signaling reveals both cooperative and antagonistic interactions with p75 neurotrophic factor receptor in axon patterning	6
Taurine inhibits KDM3a production and microglia activation in lipopolysaccharide-treated mice and BV-2 cells	6
Effect of germ-free status on transcriptional profiles in the nucleus accumbens and transcriptomic response to chronic morphine	6
Functional heterogeneity in the pineal projection neurons of zebrafish	6
Differential expression of glutamatergic receptor subunits in the hippocampus in carioca high- and low-conditioned freezing rats	6
Inhibitory signaling in mammalian olfactory transduction potentially mediated by Gαo	6
Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence	6
Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes	6
microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice	5
Dystrophic Dmd rats show early neuronal changes (increased S100β and Tau5) at 8 months, supporting severe dystropathology in this rodent model of Duchenne muscular dystrophy	5
Implications of increased S100β and Tau5 proteins in dystrophic nerves of two mdx mouse models for Duchenne muscular dystrophy	5
Logistics of neuronal protein turnover: Numbers and mechanisms	5
Kv1.1 subunits localize to cardiorespiratory brain networks in mice where their absence induces astrogliosis and microgliosis	5
The amyotrophic lateral sclerosis-linked protein TDP-43 regulates interleukin-6 cytokine production by human brain pericytes	5
IRS1 expression in hippocampus is age-dependent and is required for mature spine maintenance and neuritogenesis	5
The Tardigrade damage suppressor protein Dsup promotes DNA damage in neurons	5
GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease	5
Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice	5
Plasticity of postsynaptic nanostructure	5
Investigating developmental and disease mechanisms of the cerebellum with pluripotent stem cells	5
Correcting a widespread error: Neuroprotectant N-acetyl-L-tryptophan does not bind to the neurokinin-1 receptor	4
DNA repair pathways are altered in neural cell models of frataxin deficiency	4
Timothy syndrome iPSC modeling	4
The identification of PSEN1 p.Tyr159Ser mutation in a non-canonic early-onset Alzheimer's disease family	4
Identification of cytoskeletal proteins as binding partners of Bri2 BRICHOS domain	4
Signatures of cochlear processing in neuronal coding of auditory information	4
Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells	4
Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2	4
The effect of axotomy on firing and ultrastructure of the crayfish mechanoreceptor neurons and satellite glial cells	4
In vitro priming response in dorsal root ganglia partially mimics injury-driven pre-conditioning response and reprograms neurons for enhanced outgrowth	4
MCTP-1 modulates neurotransmitter release in C. elegans	4
Golgi stress induces upregulation of the ER-Golgi SNARE Syntaxin-5, altered βAPP processing, and Caspase-3-dependent apoptosis in NG108-15 cells	4
Loss of POGZ alters neural differentiation of human embryonic stem cells	4
Hepcidin inhibits autophagy in intracerebral hemorrhage models in vitro and in vivo	4
LINE-1 specific nuclear organization in mice olfactory sensory neurons	4
Cytoplasmic TDP-43 accumulation drives changes in C-bouton number and size in a mouse model of sporadic Amyotrophic Lateral Sclerosis	4
Differential expression of serotonin2B receptors in GABAergic and serotoninergic neurons of the rat and mouse dorsal raphe nucleus	4
Interleukin-15 modulates the response of cortical neurons to ischemia	4
Depletion of regulatory T cells exacerbates inflammatory responses after chronic cerebral hypoperfusion in mice	3
Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus	3
Systemic inflammation induced from remote extremity trauma is a critical driver of secondary brain injury	3
Alpha-synuclein negatively controls cell proliferation in dopaminergic neurons	3
Inactivation of vimentin in satellite glial cells affects dorsal root ganglion intermediate filament expression and neuronal axon growth in vitro	3
GPR3 accelerates neurite outgrowth and neuronal polarity formation via PI3 kinase-mediating signaling pathway in cultured primary neurons	3
Defective Reelin/Dab1 signaling pathways associated with disturbed hippocampus development of homozygous yotari mice	3
Skeletal muscle sympathetic denervation disrupts the neuromuscular junction postterminal organization: A single-cell quantitative approach	3
Inhibitory mechanism of an antifungal drug, caspofungin against amyloid β peptide aggregation: Repurposing via neuroinformatics and an experimental approach	3
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation	3
Identification of novel Aβ-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease	3
Polysialylated – neural cell adhesion molecule (PSA-NCAM) promotes recovery of vision after the critical period	3
Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3	3
In vivo neuroplasticity in vestibular animal models	3
The function of FUS in neurodevelopment revealed by the brain and spinal cord organoids	3
Mechanisms of axon polarization in pyramidal neurons	3
Effects of RU486 treatment after single prolonged stress depend on the post-stress interval	3
The interaction between intestinal bacterial metabolites and phosphatase and tensin homolog in autism spectrum disorder	3
Aging lowers PEX5 levels in cortical neurons in male and female mouse brains	3
Chemogenetic inhibition of TrkB signalling reduces phrenic motor neuron survival and size	3
Transcriptional and epigenetic regulation of microglia in substance use disorders	3
Functions of the tubulin code in the C. elegans nervous system	3
Unexpected role of stress as a possible resilience mechanism upon mild traumatic brain injury (mTBI) in mice	3
A regulatory domain in the K2P2.1 (TREK-1) carboxyl-terminal allows for channel activation by monoterpenes	3
Characterization hiPSC-derived neural progenitor cells and neurons to investigate the role of NOS1AP isoforms in human neuron dendritogenesis	3
Altered hippocampal dendritic spine maturation after hypoxia-induced seizures in neonatal rats	3
Methylation at a conserved lysine residue modulates tau assembly and cellular functions	3
Decoding Parkinson's disease – iPSC-derived models in the OMICs era	3