OOIR: Observatory of International Research

Papers

(The median citation count of Molecular and Cellular Neuroscience is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Cannabinoid receptor 2 agonist AM1241 alleviates epileptic seizures and epilepsy-associated depression via inhibiting neuroinflammation in a pilocarpine-induced chronic epilepsy mouse model	56
Immunomodulatory protein from ganoderma microsporum protects against oxidative damages and cognitive impairments after traumatic brain injury	47
Impaired hippocampal neurogenesis and cognitive performance in adult DBC1-knock out mice	38
Editorial Board	30
Exosome-based therapeutics: Advancing drug delivery for neurodegenerative diseases	27
Absence of Gem1 (mammalian Miro/Rhot) mitigates alpha-synuclein toxicity in a yeast model of Parkinson's disease	24
Signatures of cochlear processing in neuronal coding of auditory information	24
Methylation at a conserved lysine residue modulates tau assembly and cellular functions	24
Reduced platelet activation and thrombus formation in male transgenic model mice of Alzheimer's disease suggests early sex-specific differences in platelet pathophysiology	24
The role of alarmins in neuroinflammation following spinal cord injury: A systematic review of the literature	23
Sex differences in susceptibility to substance use disorder: Role for X chromosome inactivation and escape?	22
Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair	21
Paternal morphine exposure in rats reduces social play in adolescent male progeny without affecting drug-taking behavior in juvenile males or female offspring	21
Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb	21
TREM2 in Alzheimer's disease: Structure, function, therapeutic prospects, and activation challenges	20
Dimethyl itaconate reprograms neurotoxic to neuroprotective primary astrocytes through the regulation of NLRP3 inflammasome and NRF2/HO-1 pathways	20
Protein phosphatases regulate the formation of Müller glia-derived progenitor cells in the chick retina	19
Astrocytes initiate autophagic flux and maintain cell viability after internalizing non-active native extracellular α-synuclein	19
In vivo neuroplasticity in vestibular animal models	18
Activation of angiotensin converting enzyme 2 promotes hippocampal neurogenesis via activation of Wnt/β-catenin signaling in hypertension	18
Combined treatment of retinoic acid with olfactory ensheathing cells protect gentamicin-induced SGNs damage in the rat cochlea in vitro	18
TAT-PPA1 protects against oxidative stress-induced loss of dopaminergic neurons	18
Differential expression of the neuronal CB1 cannabinoid receptor in the hippocampus of male Ts65Dn Down syndrome mouse model	18
The role of calcium, Akt and ERK signaling in cadmium-induced hair cell death	17
iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles	17

Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia	17
GSK-3β dysregulation in aging: Implications for tau pathology and Alzheimer's disease progression	16
Transcriptional and epigenetic regulation of microglia in substance use disorders	16
Interneurons in the CA1 stratum oriens expressing αTTP may play a role in the delayed-ageing Pol μ mouse model	16
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation	15
Editorial Board	15
The glymphatic and meningeal lymphatic systems may converge, connecting traumatic brain injury progression with chronic traumatic encephalopathy onset	13
Chemogenetic inhibition of TrkB signalling reduces phrenic motor neuron survival and size	13
Neuroprotective effect of the peroxisome proliferator-activated receptor γ agonist lobeglitazone following intracerebral hemorrhage in rats	13
Turnover of synaptic adhesion molecules	12
Synaptic logistics: Competing over shared resources	12
Vulnerability of neurofilament-expressing neurons in frontotemporal dementia	12
An in-depth association analysis of genetic variants within nicotine-related loci: Meeting in middle of GWAS and genetic fine-mapping	12
Apelin-13 can regulate adipose-derived mesenchymal stem cells to improve traumatic brain injury	11
Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine	11
Role of ALS-associated OPTN-K489E mutation in neuronal cell-death regulation	11
The mRNA expression profile of glycine receptor subunits alpha 1, alpha 2, alpha 4 and beta in female and male mice	11
Golgi stress induces upregulation of the ER-Golgi SNARE Syntaxin-5, altered βAPP processing, and Caspase-3-dependent apoptosis in NG108-15 cells	11
Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1	11
In vitro and in vivo models: What have we learnt about inner ear regeneration and treatment for hearing loss?	11
Recovery of Angelman syndrome rat deficits with UBE3A protein supplementation	11
Expanded polyQ aggregates interact with sarco-endoplasmic reticulum calcium ATPase and Drosophila inhibitor of apoptosis protein1 to regulate polyQ mediated neurodegeneration in Drosophila	11
Comparing effects of microgravity and amyotrophic lateral sclerosis in the mouse ventral lumbar spinal cord	10
A critical role for the fascin family of actin bundling proteins in axon development, brain wiring and function	10
Glycogen phosphorylase isoenzyme GPbb versus GPmm regulation of ventromedial hypothalamic nucleus glucoregulatory neurotransmitter and counter-regulatory hormone profiles during hypoglycemia: Role of	10
Peroxisome, neuropeptide, and inflammation signaling pathways uniquely impacted by opioid exposure in the hypothalamus of males and females	10
Interrogating mediators of single-cell transcriptional changes in the acute damaged cerebral cortex: Insights into endothelial-astrocyte interactions	9
Activity-dependent circuitry plasticity via the regulation of the histamine receptor level in the Drosophila visual system	9
Editorial Board	9
Efferent axons in the zebrafish lateral line degenerate following sensory hair cell ablation	9
RNA-based therapies for neurodegenerative disease: Targeting molecular mechanisms for disease modification	9
The Npc2 mouse signifies pathological changes comparable to human Niemann-Pick type C2 disease	8
A neural mass model for disturbance of alpha rhythm in the minimal hepatic encephalopathy	8
CRMP2 conditional knockout changes axonal function and ultrastructure of axons in mice corpus callosum	8
Alpha-synuclein negatively controls cell proliferation in dopaminergic neurons	8
Bridging the gap in the management of Alzheimer's disease using fecal microbiota transplantation	8
A microglial kinase ITK mediating neuroinflammation and behavioral deficits in traumatic brain injury	8
VPS35 deficiency in the embryonic cortex leads to prenatal cell loss and abnormal development of axonal connectivity	8
The elastin-derived peptide (VGVAPG) activates autophagy in neuroblastoma (SH-SY5Y) cells via peroxisome proliferator-activated receptor gamma (PPARγ)	7
microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice	7
Molecular mechanisms of AMPAR reversible stabilization at synapses	7
Editorial Board	7
Editorial Board	7
Polygenic influences on the behavioral effects of alcohol withdrawal in a mixed-ancestry population from the collaborative study on the genetics of alcoholism (COGA)	7
Cdc42 activation is necessary for heterosynaptic cooperation and competition	7
Neuronal endoplasmic reticulum architecture and roles in axonal physiology	7
Olfactory receptor coding sequences cause silencing of episomal constructs in multiple cell lines	7
Erratum to “wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models” [Mol. Cell. Neurosci. 49 (1) (2012), 44–53]	7
Expression of the human herpesvirus 6A latency-associated transcript U94A impairs cytoskeletal functions in human neural cells	7
Knockdown of BMP7 induced oligodendrocyte apoptosis, demyelination and motor function loss	7

Editorial Board	6
Special issue: Synaptic logistics — Maintenance of synaptic composition, properties and function	6
Glutamine metabolism in diseases associated with mitochondrial dysfunction	6
BDNF-modified human umbilical cord mesenchymal stem cells-derived dopaminergic-like neurons improve rotation behavior of Parkinson's disease rats through neuroprotection and anti-neuroinflammation	6
Identifying targets to prevent aminoglycoside ototoxicity	6
Recovery of motor function is associated with rescue of glutamate biomarkers in the striatum and motor cortex following treatment with Mucuna pruriens in a murine model of Parkinsons disease	6
The exocyst subunit Sec15 is critical for proper synaptic development and function at the Drosophila NMJ	6
Cardiolipin released by microglia can act on neighboring glial cells to facilitate the uptake of amyloid-β (1–42)	6
Circular RNA regulation and function in drug seeking phenotypes	5
A novel in vitro model for investigating oligodendroglial maturation and myelin deposition under demyelinating and remyelinating conditions: Impact of microglial depletion and repopulation	5
Editorial Board	5
GPR3 accelerates neurite outgrowth and neuronal polarity formation via PI3 kinase-mediating signaling pathway in cultured primary neurons	5
Editorial Board	5
Ubiquitous calpastatin overexpression in brain-injured mice attenuates motor and cognitive behavioral deficits without overt neuroprotection	5
Cypin binds to tubulin heterodimers and microtubule protofilaments and regulates microtubule spacing in developing hippocampal neurons	5
Editorial Board	5
Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy	5
Intermitochondrial signaling regulates the uniform distribution of stationary mitochondria in axons	5
Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice	5
Single subanesthetic dose of ketamine exerts antioxidant and antidepressive-like effect in ACTH-induced preclinical model of depression	5
The potential roles of excitatory-inhibitory imbalances and the repressor element-1 silencing transcription factor in aging and aging-associated diseases	5
Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregates	5
Experience-dependent Tip60 nucleocytoplasmic transport is regulated by its NLS/NES sequences for neuroplasticity gene control	5
Heparan sulfate proteoglycans: Mediators of cellular and molecular Alzheimer's disease pathogenic factors via tunnelling nanotubes?	5
Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3	4
Proteomic characterization of spinal cord synaptoneurosomes from Tg-SOD1/G93A mice supports a role for MNK1 and local translation in the early stages of amyotrophic lateral sclerosis	4
Sex-dependent effects of monomeric α-synuclein on calcium and cell death of lateral hypothalamic mouse neurons are altered by orexin	4
Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment	4
Editorial Board	4
Editorial Board	4
β2-adrenoceptor agonist formoterol attenuates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis in microglia through enhancing IκBα/NF-κB inhibition, SQSTM1/p62-dependent selective autophagy	4
Activation of the unfolded protein response by Connexin47 mutations associated with Pelizaeus-Merzbacher-like disease	4
Protein transport from pre- and postsynapse to the nucleus: Mechanisms and functional implications	4
Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease	4
β-Hydroxybutyrate enhances astrocyte glutamate uptake through EAAT1 expression regulation	4
Interleukin-4 activates divergent cell-intrinsic signals to regulate retinal cell proliferation induced by classical growth factors	4
Effect of germ-free status on transcriptional profiles in the nucleus accumbens and transcriptomic response to chronic morphine	4
SMN loss dysregulates microtubule-associated proteins in spinal muscular atrophy model	3
Modulation of Nrf-2/HO-1/HIF-1α/TFAM pathways by Arbutin in rat model of cerebral ischemic stroke	3
iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death	3
RBM15 relies on m6A modification to inhibit UBE2C, alleviating hippocampal neuronal injury by limiting microglial inflammation	3
Computational insights into mRNA and protein dynamics underlying synaptic plasticity rules	3
Early life adversity: Epigenetic regulation underlying drug addiction susceptibility	3
Identifying potential genes driving ferroptosis in the substantia nigra and dopaminergic neurons in Parkinson's disease	3
Sphingosine-1-phosphate receptor 3 promotes neuronal apoptosis via the TNF-α/caspase-3 signaling pathway after acute intracerebral hemorrhage	3
Microfluidics in neural extracellular vesicles characterization for early Alzheimer's disease diagnosis	3
Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes	3
Profiling transcriptomic responses of human stem cell-derived medium spiny neuron-like cells to exogenous phasic and tonic neurotransmitters	3
Synaptic transmission at the vestibular hair cells of amniotes	3
DAPK1 induces motor neuron apoptosis in hSOD1G93A-linked amyotrophic lateral sclerosis via regulating the Xiap/JNK pathway	3
Disease modifying effects of the amyloid-beta protofibril-selective antibody mAb158 in aged Tg2576 transgenic mice	3
Axonal transport deficits in neuropsychiatric disorders	3
Estradiol activates the CaMKKβ/AMPK pathway to enhance neurite outgrowth in cultured adult sensory neurons	3
Regulation of hippocampal excitatory synapse development by the adhesion G-protein coupled receptor brain-specific angiogenesis inhibitor 2 (BAI2/ADGRB2)	3
Editorial Board	3
Taurine inhibits KDM3a production and microglia activation in lipopolysaccharide-treated mice and BV-2 cells	3
Mitochondrial fission and fusion in neurodegenerative diseases:Ca2+ signalling	3
Synaptic logistics: The presynaptic scaffold protein Piccolo a nodal point tuning synaptic vesicle recycling, maintenance and integrity	3
Editorial Board	3