OOIR: Observatory of International Research

Papers

(The median citation count of Seminars in Immunology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Fibroblast heterogeneity in tumor micro-environment: Role in immunosuppression and new therapies	127
Outer membrane vesicle vaccines	102
The role of dendritic cells in cancer and anti-tumor immunity	92
Emerging concepts in PD-1 checkpoint biology	85
Memory CD8+ T cell responses to cancer	83
The immunology of SARS-CoV-2 infections and vaccines	82
Dendritic cells in the tumor microenvironment: prognostic and theranostic impact	80
The continued advance of vaccine adjuvants – ‘we can work it out’	72
Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity	72
APOE mediated neuroinflammation and neurodegeneration in Alzheimer’s disease	57
New viral vectors for infectious diseases and cancer	54
T cell immunity to SARS-CoV-2	54
Key recent advances in TB vaccine development and understanding of protective immune responses against Mycobacterium tuberculosis	53
The role of neutrophil extracellular traps in cancer progression and metastasis	46
Tertiary Lymphoid Structures and B cells: Clinical impact and therapeutic modulation in cancer	45
Poly-ICLC, a multi-functional immune modulator for treating cancer	45
Nanobodies in cancer	43
Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair	40
Non-coding RNA-based regulation of inflammation	39
G-CSF – A double edge sword in neutrophil mediated immunity	38
Prognostic significance of tumor-associated macrophages: past, present and future	38
Immunological approaches to HIV cure	37
Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion	37
Epitope prediction and identification- adaptive T cell responses in humans	35
Transforming vaccine development	35

Quantum leap of monoclonal antibody (mAb) discovery and development in the COVID-19 era	33
HIV persistence in subsets of CD4+ T cells: 50 shades of reservoirs	31
HIV replication and latency in monocytes and macrophages	31
The complexity of neutrophils in health and disease: Focus on cancer	30
HIV vaccinology: 2021 update	30
Antibody-guided structure-based vaccines	29
NK cells in the tumor microenvironment: Prognostic and theranostic impact. Recent advances and trends	29
E-series resolvin metabolome, biosynthesis and critical role of stereochemistry of specialized pro-resolving mediators (SPMs) in inflammation-resolution: Preparing SPMs for long COVID-19, human clinic	29
The neglected brothers come of age: B cells and cancer	28
G-CSF, the guardian of granulopoiesis	28
Broadly neutralizing antibodies for HIV-1 prevention and therapy	27
Radiotherapy: An immune response modifier for immuno-oncology	27
Macrophage regulation & function in helminth infection	26
The dual role of neutrophils in cancer	26
Complement component C3: A structural perspective and potential therapeutic implications	25
GM-CSF: Master regulator of the T cell-phagocyte interface during inflammation	24
Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategies	24
Targeting GM-CSF in inflammatory and autoimmune disorders	23
Adoptive T cell therapy: Boosting the immune system to fight cancer	22
Colony stimulating factors in the nervous system	22
Unexpected connections of the IL-23/IL-17 and IL-4/IL-13 cytokine axes in inflammatory arthritis and enthesitis	22
IL-3 in the development and function of basophils	22
Metabolic regulation of T cells in the tumor microenvironment by nutrient availability and diet	22
The impact of immunopeptidomics: From basic research to clinical implementation	20
Dimensions of neutrophil life and fate	20
IL-33: A central cytokine in helminth infections	20
Residual immune dysfunction under antiretroviral therapy	20
Immune response after central nervous system injury	19
Tumor resident regulatory T cells	18
Human challenge trials in vaccine development	17
Specialized pro-resolving mediators as modulators of immune responses	17
Immunomodulatory effects of G-CSF in cancer: Therapeutic implications	17
Translational advances of melanocortin drugs: Integrating biology, chemistry and genetics	17
Heterologous humoral immunity to human and zoonotic coronaviruses: Aiming for the achilles heel	16
Therapeutic exploitation of neutrophils to fight cancer	16
Versatile neutrophil functions in cancer	16
A major mechanism for immunomodulation: Dietary fibres and acid metabolites	15
Tissue-resident memory-like T cells in tumor immunity: Clinical implications	15
Clinical evaluation of colony-stimulating factor 1 receptor inhibitors	15
Innovations in lymph node targeting nanocarriers	15
Adaptive NK cell response to human cytomegalovirus: Facts and open issues	14
Pathways of MHC I cross-presentation of exogenous antigens	14
Nanoparticle theranostics in cardiovascular inflammation	13
Nanoparticles for generating antigen-specific T cells for immunotherapy	13
Targeting dendritic cells to advance cross-presentation and vaccination outcomes	13
Pathophysiology of neurodegenerative diseases: An interplay among axonal transport failure, oxidative stress, and inflammation?	13
Basophils in antihelminth immunity	12
Neutrophil metabolism in the cancer context	12
Activation of B cells in Tertiary Lymphoid Structures in cancer: Anti-tumor or anti-self?	12
Formyl peptide receptor 2 and heart disease	12

Lessons in type 2 immunity: Neutrophils in Helminth infections	12
Shocking HIV-1 with immunomodulatory latency reversing agents	12
Impaired innate antiviral defenses in COVID-19: Causes, consequences and therapeutic opportunities	11
Humoral immune responses: Unsung heroes of the war on cancer	11
Connecting the dots: Neutrophils at the interface of tissue regeneration and cancer	11
IL-34, the rationale for its expression in physiological and pathological conditions	11
The evolving biology of cross-presentation	10
Microbiota-targeted therapies in inflammation resolution	10
Complement activation in cancer: Effects on tumor-associated myeloid cells and immunosuppression	10
Discovering C3 targeting therapies for paroxysmal nocturnal hemoglobinuria: Achievements and pitfalls	10
CD40-CD154: A perspective from type 2 immunity	10
Natural killer cells and type 1 innate lymphoid cells in cancer	10
Cellular and molecular diversity in Rheumatoid Arthritis	10
Checkpoint blockade toxicities: Insights into autoimmunity and treatment	10
Impact of cancer cell-intrinsic features on neutrophil behavior	9
What’s self got to do with it: Sources of heterogeneity among naive T cells	9
Complexity of immune responses in COVID-19	9
Antigen discovery for the development of cancer immunotherapy	9
The clinical heterogeneity of adult onset Still’s disease may underlie different pathogenic mechanisms. Implications for a personalised therapeutic management of these patients	9
Tumor associated macrophage in HPV+ tumors: Between immunosuppression and inflammation	9
Pyroptosis: A road to next-generation cancer immunotherapy	9
Microbial mismanagement: how inadequate treatments for vaginal dysbiosis drive the HIV epidemic in women	9
Multidimensional molecular controls defining NK/ILC1 identity in cancers	9
Myeloid dysregulation and therapeutic intervention in COVID-19	9
Immunity to fungi in the lung	9
C3-targeted host-modulation approaches to oral inflammatory conditions	9
Pyroptosis-induced inflammation and tissue damage	9
Emerging features of MAIT cells and other unconventional T cell populations in human viral disease and vaccination.	8
Nanoalum adjuvanted vaccines: small details make a big difference	8
Targeting novel inhibitory receptors in cancer immunotherapy	8
The gut-enthesis axis and the pathogenesis of Spondyloarthritis	8
Polyvalent design in the cGAS-STING pathway	8
Current insights in mouse iNKT and MAIT cell development using single cell transcriptomics data	8
The biogenesis of the immunopeptidome	8
The gut-brain vascular axis in neuroinflammation	8
Contemplating immunopeptidomes to better predict them	8
Redefining microglia states: Lessons and limits of human and mouse models to study microglia states in neurodegenerative diseases	7
IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC	7
Neglected no more: B cell-mediated anti-tumor immunity	7
The tumor microenvironment: Prognostic and theranostic impact. Recent advances and trends	7
Pro-resolving therapies as potential adjunct treatment for infectious diseases: Evidence from studies with annexin A1 and angiotensin-(1-7)	7
Myeloid derived suppressor cells in tumor microenvironment: Interaction with innate lymphoid cells	7
Segmentation of biomedical images based on a computational topology framework	6
Immune aging – A mechanism in autoimmune disease	6
Cellular and molecular diversity in Sjogren’s syndrome salivary glands: Towards a better definition of disease subsets	6
Exploiting Ca2+ signaling in T cells to advance cancer immunotherapy	6
Resolving inflammatory links between myocardial infarction and vascular dementia	6
Cellular and molecular diversity in spondyloarthritis	6
Aging unconventionally: γδ T cells, iNKT cells, and MAIT cells in aging	6
Empowering patients from within: Emerging nanomedicines for in vivo immune cell reprogramming	6
Immunomodulatory and immunoregulatory nanomedicines for autoimmunity	6
Cross-presentation by the others	6
Diversity of NF-κB signalling and inflammatory heterogeneity in Rheumatic Autoimmune Disease	6
Pyroptosis in defense against intracellular bacteria	5
Viral- and tumor-reactive natural killer cells	5
Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research – 20 years of experience and future perspectives	5
DNGR-1-mediated cross-presentation of dead cell-associated antigens	5
MHC-dressing on dendritic cells: Boosting anti-tumor immunity via unconventional tumor antigen presentation	5
Natural killer cell responses to human oncogenic γ-herpesvirus infections	5
Development of γδ T cells in the thymus – A human perspective	5
Interrogating the microenvironmental landscape of tumors with computational image analysis approaches	5
Emerging opportunities for C3 inhibition in the eye	5
Viral T-cell epitopes – Identification, characterization and clinical application	5
Using mass spectrometry to identify neoantigens in autoimmune diseases: The type 1 diabetes example	5