American Journal of Respiratory Cell and Molecular Biology

Article	Citations
Selection of Invasive and Metastatic Subpopulations from a Human Lung Adenocarcinoma Cell Line	350
Proteomic Analysis of Exosomes Isolated from Human Malignant Pleural Effusions	304
Release and Activity of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 by Alveolar Macrophages from Patients with Chronic Obstructive Pulmonary Disease	302
Fibroblasts from Idiopathic Pulmonary Fibrosis and Normal Lungs Differ in Growth Rate, Apoptosis, and Tissue Inhibitor of Metalloproteinases Expression	277
Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atop	255
Heme Oxygenase-1/Carbon Monoxide	226
Organic Compounds from Diesel Exhaust Particles Elicit a Proinflammatory Response in Human Airway Epithelial Cells and Induce Cytochrome p450 1A1 Expression	210
Production of Interleukin 13 by Alveolar Macrophages from Normal and Fibrotic Lung	209
Airway Mucus	204
Polyspecific Cation Transporters Mediate Luminal Release of Acetylcholine from Bronchial Epithelium	171
The Effect of Diesel Exhaust Particles on Cell Function and Release of Inflammatory Mediators from Human Bronchial Epithelial Cells In Vitro	159
Tumor Necrosis Factor- α –Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth Muscle Cells	150
The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease	149
Synergistic Inhibition by β2-Agonists and Corticosteroids on Tumor Necrosis Factor- α –Induced Interleukin-8 Release from Cultured Human Airway Smooth-Muscle Cells	148
Increased expression of the monocyte chemoattractant protein-1 in bronchial tissue from asthmatic subjects.	148
Surfactant Protein-A Binds Group B Streptococcus Enhancing Phagocytosis and Clearance from Lungs of Surfactant Protein-A–Deficient Mice	146
α,β-Unsaturated Aldehydes in Cigarette Smoke Release Inflammatory Mediators from Human Macrophages	141
Asbestos, Lung Cancers, and Mesotheliomas	134
Inverse Effects of Interleukin-6 on Apoptosis of Fibroblasts from Pulmonary Fibrosis and Normal Lungs	124
Sonic Hedgehog Signaling in the Lung. From Development to Disease	120
Gene Expression from Adeno-associated Virus Vectors in Airway Epithelial Cells	118
Gene Expression Profiling of Human Lung Tissue from Smokers with Severe Emphysema	117
Vascular endothelial growth factor mRNA increases in alveolar epithelial cells during recovery from oxygen injury.	115
Autocrine Ligands for the Epidermal Growth Factor Receptor Mediate Interleukin-8 Release from Bronchial Epithelial Cells in Response to Cigarette Smoke	113
Interleukin-13 Induces Goblet Cell Differentiation in Primary Cell Culture from Guinea Pig Tracheal Epithelium	112

Enhanced Generation of Free Radicals from Phagocytes Induced by Mineral Dusts	112
Reactive Oxygen and Nitrogen Intermediates Increase Transforming Growth Factor– β 1 Release from Human Epithelial Alveolar Cells through Two Different Mechanisms	108
Mechanical Stress Triggers Selective Release of Fibrotic Mediators from Bronchial Epithelium	108
Defining the Activated Fibroblast Population in Lung Fibrosis Using Single-Cell Sequencing	105
Effect of Cigarette Smoke on the Permeability and IL-1 β and sICAM-1 Release from Cultured Human Bronchial Epithelial Cells of Never-Smokers, Smokers, and Patients with Chronic Obstructive Pulmonar	105
Specific Binding of Endothelin on Human Bronchial Smooth Muscle Cells in Culture and Secretion of Endothelin-like Material from Bronchial Epithelial Cells	105
Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis	104
Upregulation of the p75 But Not the p55 TNF- α Receptor mRNA after Silica and Bleomycin Exposure and Protection from Lung Injury in Double Receptor Knockout Mice	102
Peroxisome Proliferator-Activated Receptor-γ Is Deficient in Alveolar Macrophages from Patients with Alveolar Proteinosis	101
Iron and reactive oxygen species in the asbestos-induced tumor necrosis factor-alpha response from alveolar macrophages.	100
Tumor Necrosis Factor- α –Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth-Muscle Cells	98
Increased levels of endothelin-1 in bronchoalveolar lavage fluid from patients with systemic sclerosis contribute to fibroblast mitogenic activity in vitro.	97
Structural Comparison of Recombinant Pulmonary Surfactant Protein SP-A Derived from Two Human Coding Sequences: Implications for the Chain Composition of Natural Human SP-A	95
Analysis of respiratory mucus glycoproteins in asthma: a detailed study from a patient who died in status asthmaticus.	95
Apoptosis, Proliferation, and Expression of Bcl-2, Fas, and Fas Ligand in Bronchial Biopsies from Asthmatics	93
Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo	91
Particulate Matter Induces Translocation of IL-6 from the Lung to the Systemic Circulation	90
Autophagy Activation in Asthma Airways Remodeling	90
Interleukin-25–Induced Chemokines and Interleukin-6 Release from Eosinophils Is Mediated by p38 Mitogen-Activated Protein Kinase, c-Jun N-Terminal Kinase, and Nuclear Factor-κB	89
Lysozyme Secretion by Submucosal Glands Protects the Airway from Bacterial Infection	86
Gene Expression in Bronchoalveolar Lavage Cells from Scleroderma Patients	85
Low Molecular Weight Hyaluronan from Stretched Lung Enhances Interleukin-8 Expression	83
Dissociation of Airway Hyperresponsiveness from Immunoglobulin E and Airway Eosinophilia in a Murine Model of Allergic Asthma	83
In situ expression of the cell adhesion molecules in bronchial tissues from asthmatics with air flow limitation: in vivo evidence of VCAM-1/VLA-4 interaction in selective eosinophil infiltration.	83
Chronic Lung Disease in the Preterm Infant. Lessons Learned from Animal Models	83
Cigarette Smoke–Induced Damage-Associated Molecular Pattern Release from Necrotic Neutrophils Triggers Proinflammatory Mediator Release	82
The Cyclin-Dependent Kinase Inhibitor p21 Protects the Lung from Oxidative Stress	82
Induction of the Lung Myofibroblast PDGF Receptor System by Urban Ambient Particles from Mexico City	81
Pirfenidone: Molecular Mechanisms and Potential Clinical Applications in Lung Disease	81
A2BAdenosine Receptors Induce IL-19 from Bronchial Epithelial Cells, Resulting in TNF-α Increase	79
Molecular Pathogenesis of Lymphangioleiomyomatosis	77
Methods in Lung Microbiome Research	76
ATP Modulates Anti-IgE–Induced Release of Histamine from Human Lung Mast Cells	76
Evidence for Different Human Tracheobronchial Mucin Peptides Deduced from Nucleotide cDNA Sequences	73
Neuropeptide-containing nerves in endobronchial biopsies from asthmatic and nonasthmatic subjects.	73
Nucleotide-Mediated Mucin Secretion from Differentiated Human Bronchial Epithelial Cells	73
Interleukin-11 and Interleukin-6 Protect Cultured Human Endothelial Cells from H2O2-Induced Cell Death	71
Hydrogen Sulfide Inhibits Proliferation and Release of IL-8 from Human Airway Smooth Muscle Cells	69
Glutamine Metabolism Is Required for Collagen Protein Synthesis in Lung Fibroblasts	69
Platelet-Derived Growth Factor Signaling in the Lung. From Lung Development and Disease to Clinical Studies	67
Caveolin-1 Deficiency Protects from Pulmonary Fibrosis by Modulating Epithelial Cell Senescence in Mice	67
Harnessing Regulatory T cells to Suppress Asthma	67
Degradation of Annexin I in Bronchoalveolar Lavage Fluid from Patients with Cystic Fibrosis	67
Intercellular Communication between Airway Epithelial Cells Is Mediated by Exosome-Like Vesicles	67
Alveolar macrophages from patients with beryllium disease and sarcoidosis express increased levels of mRNA for tumor necrosis factor-alpha and interleukin-6 but not interleukin-1 beta.	67
A Technique to Harvest Viable Tracheobronchial Epithelial Cells from Living Human Donors	65
Simvastatin Improves Epithelial Dysfunction and Airway Hyperresponsiveness	64
Long-Term Cultures of Polarized Airway Epithelial Cells from Patients with Cystic Fibrosis	63
Purification and Characterization of PLUNC from Human Tracheobronchial Secretions	63
Expression and Regulation of Inducible Nitric Oxide Synthase from Human Primary Airway Epithelial Cells	61

Pulmonary Inflammation Induced by Bacteria-Free Outer Membrane Vesicles from Pseudomonas aeruginosa	61
Endogenously Released Endothelin-1 from Human Pulmonary Artery Smooth Muscle Promotes Cellular Proliferation	60
Loss of Epithelial Integrity Resulting from E-Cadherin Dysfunction Predisposes Airway Epithelial Cells to Adenoviral Infection	60
Induction of Multinucleated Giant Cell Formation from In Vitro Culture of Human Monocytes with Interleukin-3 and Interferon-γ: Comparison with Other Stimulating Factors	60
Goblet Cells Are Derived from a FOXJ1-Expressing Progenitor in a Human Airway Epithelium	59
An ELISA Method for the Quantitation of Tracheal Mucins from Human and Nonhuman Primates	59
Airway Delivery of Soluble Factors from Plastic-Adherent Bone Marrow Cells Prevents Murine Asthma	58
Applications and Approaches for Three-Dimensional Precision-Cut Lung Slices. Disease Modeling and Drug Discovery	58
Gene Expression of Macrophage Inflammatory Protein-1α from Human Blood Monocytes and Alveolar Macrophages Is Inhibited by Interleukin-4	58
Fibronectin on the Surface of Extracellular Vesicles Mediates Fibroblast Invasion	58
A Novel Method for Isolating Individual Cellular Components from the Adult Human Distal Lung	57
Cigarette Smoking Causes Sequestration of Polymorphonuclear Leukocytes Released from the Bone Marrow in Lung Microvessels	57
Altered Carbohydrate Composition of Salivary Mucins from Patients with Cystic Fibrosis and the Adhesion of Pseudomonas aeruginosa	56
Systems Analysis of the Human Pulmonary Arterial Hypertension Lung Transcriptome	56
Tissue-Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation	55
Dendritic cells and their precursors isolated from human bronchoalveolar lavage: immunocytologic and functional properties.	54
PAI-1 Regulation of TGF-β1–induced Alveolar Type II Cell Senescence, SASP Secretion, and SASP-mediated Activation of Alveolar Macrophages	53
Plasminogen-Mediated Activation and Release of Hepatocyte Growth Factor from Extracellular Matrix	53
Reduced Expression of IRF7 in Nasal Epithelial Cells from Smokers after Infection with Influenza	53
Synergistic Effect of Diesel Organic Extracts and Allergen Der p 1 on the Release of Chemokines by Peripheral Blood Mononuclear Cells from Allergic Subjects	53
Deficiency in Inducible Nitric Oxide Synthase Protects Mice from Ozone-Induced Lung Inflammation and Tissue Injury	53
Alveolar Macrophages from Human Immunodeficiency Virus–Infected Persons Demonstrate Impaired Oxidative Burst Response to Pneumocystis carinii In Vitro	52
Isolation and Partial Characterization of Subpopulations of Alveolar Macrophages, Granulocytes, and Highly Enriched Interstitial Macrophages from Rat Lung	51
Induction of Telomerase Activity in Fibroblasts from Bleomycin-Injured Lungs	50
Impaired E Prostanoid2 Expression and Resistance to Prostaglandin E2 in Nasal Polyp Fibroblasts from Subjects with Aspirin-Exacerbated Respiratory Disease	49
Ion Composition and Rheology of Airway Liquid from Cystic Fibrosis Fetal Tracheal Xenografts	49
Coupled Nucleotide and Mucin Hypersecretion from Goblet-Cell Metaplastic Human Airway Epithelium	48
Extracellular Vesicles from Fibroblasts Induce Epithelial-Cell Senescence in Pulmonary Fibrosis	48
Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice	48
Spiruchostatin A Inhibits Proliferation and Differentiation of Fibroblasts from Patients with Pulmonary Fibrosis	48
TGF-beta1 inhibits the release of histamine and tumor necrosis factor-alpha from mast cells through an autocrine pathway.	48
Palmitic Acid–Rich High-Fat Diet Exacerbates Experimental Pulmonary Fibrosis by Modulating Endoplasmic Reticulum Stress	47
Potential Role of Endothelin-1 in Pulmonary Fibrosis	47
Differential expression of the urokinase receptor in fibroblasts from normal and fibrotic human lungs.	47
IL-9 Stimulates Release of Chemotactic Factors from Human Bronchial Epithelial Cells	47
Interleukin-8 Gene Expression from Human Alveolar Macrophages: The Role of Adherence	47
Polarization of PPD-Specific T-Cell Response of Patients with Tuberculosis from Th0 to Th1 Profile after Successful Antimycobacterial Therapy or In Vitro Conditioning with Interferon- α or In	46
A Practical Guide to the Measurement and Analysis of DNA Methylation	46
CDHR3 Asthma-Risk Genotype Affects Susceptibility of Airway Epithelium to Rhinovirus C Infections	46
Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction	46
Impairment of Fatty Acid Oxidation in Alveolar Epithelial Cells Mediates Acute Lung Injury	46
Impaired Myofibroblast Dedifferentiation Contributes to Nonresolving Fibrosis in Aging	45
Isolation, Cultivation, and Partial Characterization of Microvascular Endothelium Derived from Human Lung	45
Sodium Tanshinone IIA Sulfonate Inhibits Canonical Transient Receptor Potential Expression in Pulmonary Arterial Smooth Muscle from Pulmonary Hypertensive Rats	45
Intracellular C3 Protects Human Airway Epithelial Cells from Stress-associated Cell Death	45
SPEF2- and HYDIN-Mutant Cilia Lack the Central Pair–associated Protein SPEF2, Aiding Primary Ciliary Dyskinesia Diagnostics	45
Extracellular Vesicles: A New Frontier for Research in Acute Respiratory Distress Syndrome	45
Characterization of the Cytochrome P-450 Monooxygenase System in Nonciliated Bronchiolar Epithelial (Clara) Cells Isolated from Mouse Lung	44
STAT3 Regulates the Onset of Oxidant-induced Senescence in Lung Fibroblasts	44
Nonsense-mediated RNA Decay Pathway Inhibition Restores Expression and Function of W1282X CFTR	44
Normal Surfactant Pool Sizes and Inhibition-Resistant Surfactant from Mice That Overexpress Surfactant Protein A	44
Hyperoxia-induced Cellular Senescence in Fetal Airway Smooth Muscle Cells	44
Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts	44
Phenotypic Distribution of T Cells in Human Nasal Mucosa Differs from That in the Gut	44
Vaporized E-Cigarette Liquids Induce Ion Transport Dysfunction in Airway Epithelia	44
Tumor Necrosis Factor- α Mediates Lipopolysaccharide-Induced Macrophage Inflammatory Protein-2 Release from Alveolar Epithelial Cells	43
Leukotriene B4 Release from Mast Cells in IgE-Mediated Airway Hyperresponsiveness and Inflammation	43
HIV-1 in human alveolar macrophages from infected patients is latent in vivo but replicates after in vitro stimulation.	43
Systemic Macrophage Stimulation in Rats with Silicosis: Enhanced Release of Tumor Necrosis Factor-α from Alveolar and Peritoneal Macrophages	42
Activation of Akt Protects Alveoli from Neonatal Oxygen-Induced Lung Injury	42
CircRNA-012091/PPP1R13B–mediated Lung Fibrotic Response in Silicosis via Endoplasmic Reticulum Stress and Autophagy	42
Polymorphonuclear leukocyte (PMN) migration in streptococcal pneumonia: comparison of older PMN with those recently released from the marrow.	41
Mesenchymal Stem Cell Extracellular Vesicles Reverse Sugen/Hypoxia Pulmonary Hypertension in Rats	41
Morphologic and functional properties of bronchial cells isolated from normal and asthmatic subjects.	41
Isolation and Characterization of a Peroxidase from the Airway	41
Toll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via Exosomes	41
Competition between Elastase and Related Proteases from Human Neutrophil for Binding to α1-Protease Inhibitor	41
Expression and Regulation of Tumor Necrosis Factor in Macrophages from Cystic Fibrosis Patients	41
The effect of conditioned medium from cultured human bronchial epithelial cells on eosinophil and neutrophil chemotaxis and adherence in vitro.	41
Monocyte Chemoattractant Protein–1 Released from Alveolar Macrophages Mediates the Systemic Inflammation of Acute Alveolar Hypoxia	40
Isolation of Epithelial, Endothelial, and Immune Cells from Lungs of Transgenic Mice with Oncogene-Induced Lung Adenocarcinomas	40
Characterization of phospholipase A2 from human nasal lavage.	40
Histamine Affects Interleukin-4, Interleukin-5, and Interferon- γ Production by Human T Cell Clones from the Airways and Blood	39
Transforming Growth Factor- β Secreted from CD4+ T Cells Ameliorates Antigen-Induced Eosinophilic Inflammation	39
From Birds to Humans	39
Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome	38
Hypersensitivity Pneumonitis: Whole Micropolyspora faeni or Antigens Thereof Stimulate the Release of Proinflammatory Cytokines from Macrophages	38
Alterations of ambient oxygen tension modulate the expression of tumor necrosis factor and macrophage inflammatory protein-1 alpha from murine alveolar macrophages.	38
IL-13–regulated Macrophage Polarization during Granuloma Formation in an In Vitro Human Sarcoidosis Model	38
Decreased CXCR3 Expression in CD4+ T Cells Exposed to Asbestos or Derived from Asbestos-Exposed Patients	38

Pulmonary Neuroendocrine Cells Secrete γ-Aminobutyric Acid to Induce Goblet Cell Hyperplasia in Primate Models	38
Cigarette Smoking Exacerbates Skeletal Muscle Injury without Compromising Its Regenerative Capacity	37
Cyclic AMP-dependent Phosphorylation of a 26 kD Axonemal Protein in Ovine Cilia Isolated from Small Tissue Pieces	37
Sex Differences in Pulmonary Responses to Ozone in Mice. Role of the Microbiome	37
Therapeutic Role for Mannose-Binding Lectin in Cigarette Smoke–Induced Lung Inflammation?	37
Stretch-activated Piezo1 Channel in Endothelial Cells Relaxes Mouse Intrapulmonary Arteries	37
Fatty Acid Oxidation Protects against Hyperoxia-induced Endothelial Cell Apoptosis and Lung Injury in Neonatal Mice	37
Oxidative Stress Induces Arachidonate Release from Human Lung Cells through the Epithelial Growth Factor Receptor Pathway	37
Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension	37
Improving the Quality and Reproducibility of Flow Cytometry in the Lung. An Official American Thoracic Society Workshop Report	37
Airborne Indoor Particles from Schools Are More Toxic than Outdoor Particles	36
Mycobacterium tuberculosis–Induced Activation Accelerates Apoptosis in Peripheral Blood Neutrophils from Patients with Active Tuberculosis	36
Recombinant Human Monocyte/Neutrophil Elastase Inhibitor Protects Rat Lungs against Injury from Cystic Fibrosis Airway Secretions	36
Activated Human Lung Fibroblasts Produce Extracellular Vesicles with Antifibrotic Prostaglandins	35
N-Acetylcysteine Protects Murine Alveolar Type II Cells from Cigarette Smoke Injury in a Nuclear Erythroid 2–Related Factor–2–Independent Manner	35
8-iso-PGE2 Stimulates Anion Efflux from Airway Epithelial Cells via the EP4 Prostanoid Receptor	35
Matrix Proteins from Smoke-Exposed Fibroblasts Are Pro-proliferative	35
Effects of Sustained and Intermittent Hypoxia on Human Lung Cancer Cells	35
Inhibition of Glutaminase 1 Attenuates Experimental Pulmonary Fibrosis	35
Pneumocystis carinii Induces the Release of Arachidonic Acid and its Metabolites from Alveolar Macrophages	35
Efficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation–Driven Airway Remodeling	35
Combination Therapy Targeting Platelet Activation and Virus Replication Protects Mice against Lethal Influenza Pneumonia	35
Omics and the Search for Blood Biomarkers in Chronic Obstructive Pulmonary Disease. Insights from COPDGene	35
FGFR2 Is Required for AEC2 Homeostasis and Survival after Bleomycin-induced Lung Injury	35
Cultured Lung Fibroblasts from Ovalbumin-Challenged “Asthmatic” Mice Differ Functionally from Normal	35