American Journal of Respiratory Cell and Molecular Biology

Article	Citations
Extracellular Vesicle ASC: A Novel Mediator for Lung–Brain Axis in Preterm Brain Injury	69
IL-1β Induces a Proinflammatory Fibroblast Microenvironment that Impairs Lung Progenitors’ Function	65
Novel Hemodynamic, Vascular Lesion, and Cytokine/Chemokine Differences Regarding Sex in a Pulmonary Arterial Hypertension Model	64
New Insights Relating Gasdermin B to the Onset of Childhood Asthma	60
Loss of Tbx4 Affects Postnatal Lung Development and Predisposes to Pulmonary Hypertension	58
CXCL14 Protects Against Polymicrobial Sepsis by Enhancing Antibacterial Functions of Macrophages	51
Sputum Metabolomic Signature and Dynamic Change of Cough Variant Asthma	44
Pseudomonas aeruginosa Lipid A Structural Variants Induce Altered Immune Responses	36
LPS Increases Artery but Not Airway Contraction in Precision-Cut Lung Slices from a Mouse Model of Acute Respiratory Distress Syndrome	35
Gene-ius at Work: Decoding Cell States through Expression	34
Cardiac and Pulmonary Vascular Dysfunction in Vitamin D–Deficient Bmpr2 -Mutant Rats	30
Disruption of GCN2 Pathway Aggravates Vascular and Parenchymal Remodeling during Pulmonary Fibrosis	30
Targeting S1PR2 in Sepsis, One Fragmented Mitochondrion at a Time	27
Temporal Release of IL-1 Family Members from Virally Infected Airway Epithelial Cells Suggests IL-36γ is the Early Responder	27
Neuroblastoma Suppressor of Tumorigenicity 1 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension Related to Congenital Heart Disease	27
Plasma Proteome Profiles Associated with Early Development of Lung Injury in Extremely Preterm Infants	26
Intestinal Microbiota-Derived Propionic Acid Protects Against Zinc Oxide Nanoparticle–Induced Lung Injury	26
MOTS-c Promotes Glycolysis via AMPK–HIF-1α–PFKFB3 Pathway to Ameliorate Cardiopulmonary Bypass–induced Lung Injury	26
Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2	26
MLKL Protects Pulmonary Endothelial Cells in Acute Lung Injury	26
Starving a Cell Promotes Airway Smooth Muscle Relaxation: Inhibition of Glycolysis Attenuates Excitation–Contraction Coupling	26
Delayed Microbial Maturation Durably Exacerbates Th17-driven Asthma in Mice	26
Prenatal FGFR2 Signaling via PI3K/AKT Specifies the PDGFRA+ Myofibroblast	26
Molecular Maestro in the Lung: The Sphingolipid Rheostat	26
Impact of Canadian Wildfire Smoke Exposure on Nasal Inflammation Markers in New York City Residents	26

SUMO Wrestling in the Airway Epithelium: Does It Regulate Thymic Stromal Lymphopoietin?	26
December Highlights/Papers by Junior Investigators/NIH News	25
When a DEAD-Box Protein is the Key: A Novel Role for DDX5 in Lung Pericyte Dysfunction	25
July Highlights/Papers by Junior Investigators/NIH News	25
October Highlights/Papers by Junior Investigators/NIH News	25
Expression of ACE2 —a Key SARS-CoV-2 Entry Factor—Is Not Increased in the Nasal Mucosa of People with Cystic Fibrosis	23
The Impact of Inflammation on Thermal Hyperpnea: Relevance for Heat Stress and Febrile Seizures	23
Long Story Short: Understanding Isoform-Specific Expression of FAM13A	23
Tartrate-Resistant Acid Phosphatase 5 (TRAP5) Promotes Eosinophil Migration During Allergic Asthma	23
Exposure to Urban Air Pollution Particulate Matter Modifies Th1/Th2 Mtb Immunity in the Human Lung	23
Yield and Diversity of Human Distal Lung Epithelial Cells Isolated by Different Sorting Strategies	22
Interstitial Macrophages Mediate Efferocytosis of Alveolar Epithelium during Influenza Infection	22
CSP7 Protects Alveolar Epithelial Cells by Targeting p53 -Fibrinolytic Pathways During Lung Injuries	22
Circulating Myeloid Cell–derived Extracellular Vesicles as Mediators of Indirect Acute Lung Injury	22
von Willebrand Factor: An Unhealthy Bond between Lung Endothelium and Pulmonary Fibrosis	21
Time Is Running Out in Pulmonary Arterial Hypertension: The Epigenetic Clock Is Clicking	21
ATP12A: Connecting Mucus and Fibrosis in Idiopathic Pulmonary Fibrosis	21
Multiple Fibroblast Subtypes Contribute to Matrix Deposition in Pulmonary Fibrosis	21
Adenovirus-mediated Overexpression of FcγRIIB Attenuates Pulmonary Inflammation and Fibrosis	21
MicroRNA Control Lipid-laden Alveolar Macrophages in Smokers: A Potential Therapeutic Target for Chronic Obstructive Pulmonary Disease?	21
A Glowing Opportunity to Target YAP in Lung Fibrosis	21
KAT’s in the Cradle: p300/CBP and Regulation of HIF-1 and Blood Pressure during Intermittent Hypoxia	20
Cough-Variant Asthma: The Asthma Phenotype No One Coughs About	20
When It Comes to COVID-19, Inflammation Is All the RAGE	20
LKB1 Regulates Pulmonary Hypertension Endothelial Cell Mitochondria: Another Layer of the Pulmonary Vascular Onion?	20
Achieving Excellence and Engaging Members	20
Enhanced Gαq Signaling in TSC2 -Deficient Cells Is Required for Their Neoplastic Behavior	20
October Highlights/Papers by Junior Investigators/NIH News	19
Lysophospholipid Acyltransferase 9 Promotes Emphysema Formation via Platelet-activating Factor	19
Stub1 Acetylation by CBP/p300 Attenuates Chronic Hypoxic-Driven Pulmonary Hypertension by Suppressing HIF-2α	19
A Murine Model of Mycobacterium abscessus Infection Mimics Pathology of Chronic Human Lung Disease	19
Whole-Genome Methylation Sequencing Reveals that COVID-19–induced Epigenetic Dysregulation Remains 1 Year after Hospital Discharge	19
Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3+ Regulatory T Cells	19
The Homeobox Transcription Factor CUX1 Coordinates Postnatal Epithelial Developmental Timing but Is Dispensable for Lung Organogenesis and Regeneration	19
Prorelaxant E-type Prostanoid Receptors Functionally Partition to Different Procontractile Receptors in Airway Smooth Muscle	19
PINK1/PARKIN-mediated Mitophagy: Friend or Foe in Hypoxia-induced Pulmonary Vascular Remodeling?	19
Loss of Pulmonary Endothelial Cells in Emphysema Impairs Support of Human Alveolar Epithelial Cell Growth	19
TRPV4 Regulates the Macrophage Metabolic Response to Limit Sepsis-induced Lung Injury	19
AKT Phosphorylates FAM13A and Promotes Its Degradation via CUL4A/DDB1/DCAF1 E3 Complex	19
Akt-Driven TGF-β and DKK1 Secretion Impairs F508del Cystic Fibrosis Airway Epithelium Polarity	19
Axl Mediates Resistance to Respiratory Syncytial Virus Infection Independent of Cell Attachment	18
2022-2023 Journal Award Winners	18
Improving Mitochondrial Function in Viral Infection: Targeting Cellular Metabolism	18
Acidic Enough for a Healthy Breath	18
Chronic Alcohol Intake Compromises Lung Immunity by Altering Immunometabolism in Humans and Mouse Models	18
From Protein Folding to Precision Therapy: Surfactant Protein A in the Spotlight	17
Neuromedin U Induces Pulmonary ILC2 Activation via the NMUR1 Pathway during Acute Respiratory Syncytial Virus Infection	17
A Unique CD27-IgD- B Cell Population in the Sputum of Severe Eosinophilic Asthma Associated with Airway Autoimmunity	17
A Single-Cell RNA Sequencing Atlas of the Chronic Obstructive Pulmonary Disease Distal Lung to Predict Cell–Cell Communication	17
A Locus on Chromosome 15 Contributes to Acute Ozone-induced Lung Injury in Collaborative Cross Mice	17

Peripheral Blood Omics and Other Multiplex-based Systems in Pulmonary and Critical Care Medicine	17
Intermediary Role of Lung Alveolar Type 1 Cells in Epithelial Repair upon Sendai Virus Infection	17
Soluble E-Cadherin Contributes to Airway Inflammation in Severe Asthma	17
Unveiling Organ Failure in the Critically Ill: Insights through the Metabolite Lens	16
Role of KCNK3 Dysfunction in Dasatinib-associated Pulmonary Arterial Hypertension and Endothelial Cell Dysfunction	16
Sodium Houttuyfonate Alleviates Monocrotaline-induced Pulmonary Hypertension by Regulating Orai1 and Orai2	16
Oxidized Phosphatidylcholines Trigger TRPA1 and Ryanodine Receptor–dependent Airway Smooth Muscle Contraction	16
Biomarkers of Fibrosis in Patients with COVID-19 One Year After Hospital Discharge: A Prospective Cohort Study	16
Calcium-Sensing Receptor Negative Allosteric Modulators Oppose Contraction of Mouse Airways	16
Cell Culture Differentiation and Proliferation Conditions Influence the In Vitro Regeneration of the Human Airway Epithelium	16
Alveolar and Bone Marrow–derived Macrophages Differ in Metabolism and Glutamine Utilization	16
Pirfenidone Mitigates Transforming Growth Factor-β–induced Inflammation after Viral Infection	15
April Highlights/Papers by Junior Investigators/NIH News	15
Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development	15
Loss of Iron Regulatory Protein 2 Protects Mice from Lung Inflammation during Bronchoconstriction	15
Alpha-1 Antitrypsin Deficiency: Does Increased Neutrophil Adhesion Contribute to Lung Damage?	15
An Antiviral Effect of Linoleic Acid Against Rhinovirus Infection	15
Searching for an Animal Model with Clinical Features of Scleroderma	15
Demystifying Bitter Taste Receptor Relaxation of Airway Smooth Muscle	15
Airway Immune Signatures in Severe and Fatal Infection with COVID-19	15
Multiomic Signatures of Chronic Beryllium Disease Bronchoalveolar Lavage Cells Relate to T-Cell Function and Innate Immunity	14
Redox-Dependent Activation of Lung Epithelial STAT3 Is Required for Inducible Protection against Bacterial Pneumonia	14
Comparison of Droplet- and Microwell-based Methods to Analyze Cryopreserved Human BAL Cells by Single-Cell RNA Sequencing	14
Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells	14
Recessive Mutations in CFAP74 Cause Primary Ciliary Dyskinesia with Normal Ciliary Ultrastructure	14
Tipping the Balance of Ubiquitination toward a Therapy for COVID-19	14
Therapeutic Potential of Sodium Houttuyfonate in Pulmonary Hypertension through Orai-Ca2+ Channels	14
Prenatal LPS Exposure Promotes Allergic Airway Inflammation via Long Coding RNA NONMMUT033452.2, and Protein Binding Partner, Eef1D	14
Mitochondria-derived Vesicle Packaging as a Novel Therapeutic Mechanism in Pulmonary Hypertension	14
Leveraging Microbial Symbiosis to Modulate Bronchopulmonary Dysplasia	14
TMPRSS11E-dward Scissorhands? Proteolysis Potentiates Lung Inflammation during Pathogen Insult	14
Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis	14
January Highlights/Papers by Junior Investigators/NIH News	13
Does “Skippy” Wheeze? Evidence of Airway Remodeling in the Australian Kangaroo	13
A Novel Role for γδ T Cells in Protection Against Severe Melioidosis	13
A NEAT Discovery Hints at Altered Golgi Signaling in Lung Fibrosis	13
HPS6 Deficiency Leads to Reduced Vacuolar-Type H+-ATPase and Impaired Biogenesis of Lamellar Bodies in Alveolar Type II Cells	13
DNA–Protein Kinase Catalytic Subunit as a Potential Target for Pulmonary Arterial Hypertension	13
SOX17 Prevents Endothelial–Mesenchymal Transition of Pulmonary Arterial Endothelial Cells in Pulmonary Hypertension through Mediating TGF-β/Smad2/3 Signaling	13
Pulmonary and Nonpulmonary Sepsis Differentially Modulate Lung Immunity toward Secondary Bacterial Pneumonia: A Critical Role for Alveolar Macrophages	13
A New Methodology for the Oxygen Measurement in Lung Tissue of an Aged Ferret Model Proves Hypoxia during COVID-19	13
February Highlights/Papers by Junior Investigators/NIH News	13
Pulmonary Microvascular Endothelial Cells Support Alveolar Epithelial Growth via Bone Morphogenetic Protein 6 Secretion	13
Cell Surface RNA Expression Modulates Alveolar Epithelial Function	13
Circular RNA-Cacna1d Plays a Critical Role in Sepsis-induced Lung Injury by Sponging microRNA-185-5p	12
Breath Markers of Oxidative Stress in Children with Severe Viral Lower Respiratory Tract Infection	12
The Gut–Lung Axis: What’s below the Diaphragm Is Also Important	12
Human Airway Basal Cells Undergo Reversible Squamous Differentiation and Reshape Innate Immunity	12
Enhanced Lyn Activity Causes Severe, Progressive Emphysema and Lung Cancer	12
eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-Induced Lung Fibrosis	12
July Highlights/Papers by Junior Investigators/NIH News	12
Chronic Obstructive Pulmonary Disease Airway Epithelial Cell–derived Extracellular Vesicles Spread Cellular Senescence via MicroRNA-34a	12
When Autophagy Fails: ATG7 Variants and Their Impact on Radiation Lung Injury	12
September Highlights/Papers by Junior Investigators/NIH News	12
Cytokine Regulation by Alpha-1 Antitrypsin Therapy: A Pathway Analysis of a Pilot Clinical Trial	12
Alveolar Epithelial Cell Dysfunction in Idiopathic Pulmonary Fibrosis Linked to Lipid Alterations: Therapeutic Implications	11
Does Chronic Obstructive Pulmonary Disease Originate from Different Cell Types?	11
Epigenomic Dysregulation in Youth Vapers: Implications for Disease Risk Assessment	11
Kasugamycin Is a Novel Chitinase 1 Inhibitor with Strong Antifibrotic Effects on Pulmonary Fibrosis	11
Cell Population–resolved Multiomics Atlas of the Developing Lung	11
Multiresolution 3D Optical Mapping of Immune Cell Infiltrates in Mouse Asthmatic Lung	11
Dual Pigment Epithelium-derived Factor and Hepatocyte Growth Factor Overexpression: A New Therapy for Pulmonary Hypertension	11
Amphipathic Helical Peptide L37pA Protects against Lung Vascular Endothelial Dysfunction Caused by Truncated Oxidized Phospholipids via Antagonism with CD36 Receptor	11
Bubble Trouble: Epithelial Extracellular Vesicles and Their microRNA Mischief in Chronic Obstructive Pulmonary Disease	11
A Redox-Shifted Fibroblast Subpopulation Emerges in the Fibrotic Lung	11
The RIPK3 Scaffold Regulates Lung Inflammation During Pseudomonas Aeruginosa Pneumonia	11
Collagen 18A1/Endostatin Expression in the Progression of Right Ventricular Remodeling and Dysfunction in Pulmonary Arterial Hypertension	11
Monocytes: See One Queuing Local Adaptive Immune Responses to Respiratory Viruses	10
Chronic Kidney Disease–associated Lung Injury Is Mediated by Phosphate-induced MAPK/AKT Signaling	10
Mycobacterium tuberculosis Induces Warburg Metabolism in Human Alveolar Macrophages: A Transcriptomic Analysis	10
June Highlights/Papers by Junior Investigators/NIH News	10
Unveiling an Important New Cell Type in the Lung: Microfold Cells	10
Peripheral Transcriptome of Severe Sarcoidosis Involves Dysregulation of Multiple Immunologic Systems	10
Microenvironment Regulators of Metastasis Favor Lymphangioleiomyomatosis Cell Growth and Disease Progression	10
One More Negative Regulator of AC6: S-Nitrosylation	10
Sectm1a Depletion Promotes Neutrophil Recruitment during Pneumococcal Pneumonia	10
Switching On Gene Therapy for Allergic Rhinitis: The AAVITS Approach	10
Activated Clec4nhi Neutrophils Aggravate Lung Injury in an Endothelial IGFBP7-Dependent Manner	10
Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine	10
Lipids to the Rescue in Pulmonary Fibrosis: Biosynthesis, Bioenergetics, or Epigenetics?	10

Single-Cell Profiling of Premature Neonate Airways Reveals a Continuum of Myeloid Differentiation	10
Shear Stress Markedly Alters the Proteomic Response to Hypoxia in Human Pulmonary Endothelial Cells	9
May Highlights/Papers by Junior Investigators/NIH News	9
The Potential of Extracellular Microvesicle MicroRNAs in Precapillary Pulmonary Hypertension	9
December Highlights/Papers by Junior Investigators/NIH News	9
Transcriptomics Analysis Identifies the Decline in the Alveolar Type II Stem Cell Niche in Aged Human Lungs	9
You Can’t Spell Shear without “She”: Mechanobiology and Sex Differences in Hypoxic Lung Disease	9
LAM–CAM: In Vivo Model for Rapid Analysis of Lymphangioleiomyomatosis Tumor Formation and Inhibition	9
Fetal Tracheal Occlusion Correlates with Normalized YAP Expression and Alveolar Epithelial Differentiation in Congenital Diaphragmatic Hernia	9
Reclaiming the Balance: Blocking Glutamine Uptake to Restrain Pulmonary Fibrosis	9
Cystic Fibrosis: “Ionocyte Modulators”?	9
A Functional Variant rs2122031 in ATG7 Is Associated with the Risk of Radiation Pneumonitis	9
Suppression of Allergic Asthma by Loss of Function of Miz1-mediated Th1 Skewing	9
A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis	9
Increased Circulating Extracellular Superoxide Dismutase Attenuates Platelet–Neutrophil Interactions	9
Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Emphysema	9
Engineering HMGB1-derived Peptides to Unravel Sex-Specific Mechanisms in Pulmonary Arterial Hypertension	9
Identification of Lymphangioleiomyomatosis-associated Serum MicroRNAs	9
Overexpression of Decay Accelerating Factor Mitigates Fibrotic Responses to Lung Injury	9
Circular RNA Methylation: A New Twist in Lung Fibrosis	9
Can ENaC “TIP” the Scales to Reduce Endothelial Reactive Oxygen Species and Vascular Leak during Pneumococcal Lung Injury?	9
Respiratory Epithelial Cell Surface Decoration Provides Defense against Bacterial Damage during Infection	9
Reply to Fujino et al. : Human Lung Cell Separation Strategies for Translational Research	9
On the Ultrastructure of Aberrant Basaloid Cells in Idiopathic Pulmonary Fibrosis	9
Characteristics and Regulation of Human Eosinophil ETosis In Vitro	9
“It’s a Trap”: Eosinophils Caught between Pro- and Anti-inflammatory Responses	9