American Journal of Respiratory Cell and Molecular Biology

Article	Citations
Novel Hemodynamic, Vascular Lesion, and Cytokine/Chemokine Differences Regarding Sex in a Pulmonary Arterial Hypertension Model	70
MLKL Protects Pulmonary Endothelial Cells in Acute Lung Injury	68
Temporal Release of IL-1 Family Members from Virally Infected Airway Epithelial Cells Suggests IL-36γ is the Early Responder	66
Plasma Proteome Profiles Associated with Early Development of Lung Injury in Extremely Preterm Infants	62
Neuroblastoma Suppressor of Tumorigenicity 1 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension Related to Congenital Heart Disease	60
Targeting S1PR2 in Sepsis, One Fragmented Mitochondrion at a Time	53
LPS Increases Artery but Not Airway Contraction in Precision-Cut Lung Slices from a Mouse Model of Acute Respiratory Distress Syndrome	48
Gene-ius at Work: Decoding Cell States through Expression	36
Molecular Maestro in the Lung: The Sphingolipid Rheostat	36
Disruption of GCN2 Pathway Aggravates Vascular and Parenchymal Remodeling during Pulmonary Fibrosis	33
Intestinal Microbiota-Derived Propionic Acid Protects Against Zinc Oxide Nanoparticle–Induced Lung Injury	30
Starving a Cell Promotes Airway Smooth Muscle Relaxation: Inhibition of Glycolysis Attenuates Excitation–Contraction Coupling	28
IL-1β Induces a Proinflammatory Fibroblast Microenvironment that Impairs Lung Progenitors’ Function	28
Cardiac and Pulmonary Vascular Dysfunction in Vitamin D–Deficient Bmpr2 -Mutant Rats	28
MOTS-c Promotes Glycolysis via AMPK–HIF-1α–PFKFB3 Pathway to Ameliorate Cardiopulmonary Bypass–induced Lung Injury	28
Impact of Canadian Wildfire Smoke Exposure on Nasal Inflammation Markers in New York City Residents	28
Loss of Tbx4 Affects Postnatal Lung Development and Predisposes to Pulmonary Hypertension	27
New Insights Relating Gasdermin B to the Onset of Childhood Asthma	27
Extracellular Vesicle ASC: A Novel Mediator for Lung–Brain Axis in Preterm Brain Injury	27
Pseudomonas aeruginosa Lipid A Structural Variants Induce Altered Immune Responses	26
July Highlights/Papers by Junior Investigators/NIH News	26
SUMO Wrestling in the Airway Epithelium: Does It Regulate Thymic Stromal Lymphopoietin?	26
Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2	26
CXCL14 Protects Against Polymicrobial Sepsis by Enhancing Antibacterial Functions of Macrophages	26
Sputum Metabolomic Signature and Dynamic Change of Cough Variant Asthma	26

When a DEAD-Box Protein is the Key: A Novel Role for DDX5 in Lung Pericyte Dysfunction	26
Long Story Short: Understanding Isoform-Specific Expression of FAM13A	25
December Highlights/Papers by Junior Investigators/NIH News	25
Expression of ACE2 —a Key SARS-CoV-2 Entry Factor—Is Not Increased in the Nasal Mucosa of People with Cystic Fibrosis	24
Exposure to Urban Air Pollution Particulate Matter Modifies Th1/Th2 Mtb Immunity in the Human Lung	24
Prenatal FGFR2 Signaling via PI3K/AKT Specifies the PDGFRA+ Myofibroblast	23
October Highlights/Papers by Junior Investigators/NIH News	23
Tartrate-Resistant Acid Phosphatase 5 (TRAP5) Promotes Eosinophil Migration During Allergic Asthma	23
MicroRNA Control Lipid-laden Alveolar Macrophages in Smokers: A Potential Therapeutic Target for Chronic Obstructive Pulmonary Disease?	22
Delayed Microbial Maturation Durably Exacerbates Th17-driven Asthma in Mice	22
CSP7 Protects Alveolar Epithelial Cells by Targeting p53 -Fibrinolytic Pathways During Lung Injuries	22
The Impact of Inflammation on Thermal Hyperpnea: Relevance for Heat Stress and Febrile Seizures	22
Yield and Diversity of Human Distal Lung Epithelial Cells Isolated by Different Sorting Strategies	22
Multiple Fibroblast Subtypes Contribute to Matrix Deposition in Pulmonary Fibrosis	22
Interstitial Macrophages Mediate Efferocytosis of Alveolar Epithelium during Influenza Infection	22
October Highlights/Papers by Junior Investigators/NIH News	21
Enhanced Gαq Signaling in TSC2 -Deficient Cells Is Required for Their Neoplastic Behavior	21
Cough-Variant Asthma: The Asthma Phenotype No One Coughs About	21
Stub1 Acetylation by CBP/p300 Attenuates Chronic Hypoxic-Driven Pulmonary Hypertension by Suppressing HIF-2α	21
Time Is Running Out in Pulmonary Arterial Hypertension: The Epigenetic Clock Is Clicking	21
Circulating Myeloid Cell–derived Extracellular Vesicles as Mediators of Indirect Acute Lung Injury	21
Adenovirus-mediated Overexpression of FcγRIIB Attenuates Pulmonary Inflammation and Fibrosis	21
LKB1 Regulates Pulmonary Hypertension Endothelial Cell Mitochondria: Another Layer of the Pulmonary Vascular Onion?	20
Achieving Excellence and Engaging Members	20
KAT’s in the Cradle: p300/CBP and Regulation of HIF-1 and Blood Pressure during Intermittent Hypoxia	20
A Glowing Opportunity to Target YAP in Lung Fibrosis	20
ATP12A: Connecting Mucus and Fibrosis in Idiopathic Pulmonary Fibrosis	20
When It Comes to COVID-19, Inflammation Is All the RAGE	20
von Willebrand Factor: An Unhealthy Bond between Lung Endothelium and Pulmonary Fibrosis	19
TRPV4 Regulates the Macrophage Metabolic Response to Limit Sepsis-induced Lung Injury	19
A Murine Model of Mycobacterium abscessus Infection Mimics Pathology of Chronic Human Lung Disease	19
Loss of Pulmonary Endothelial Cells in Emphysema Impairs Support of Human Alveolar Epithelial Cell Growth	19
Lysophospholipid Acyltransferase 9 Promotes Emphysema Formation via Platelet-activating Factor	19
Whole-Genome Methylation Sequencing Reveals that COVID-19–induced Epigenetic Dysregulation Remains 1 Year after Hospital Discharge	19
Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3+ Regulatory T Cells	19
Akt-Driven TGF-β and DKK1 Secretion Impairs F508del Cystic Fibrosis Airway Epithelium Polarity	19
PINK1/PARKIN-mediated Mitophagy: Friend or Foe in Hypoxia-induced Pulmonary Vascular Remodeling?	19
The Homeobox Transcription Factor CUX1 Coordinates Postnatal Epithelial Developmental Timing but Is Dispensable for Lung Organogenesis and Regeneration	19
Prorelaxant E-type Prostanoid Receptors Functionally Partition to Different Procontractile Receptors in Airway Smooth Muscle	18
2022-2023 Journal Award Winners	18
AKT Phosphorylates FAM13A and Promotes Its Degradation via CUL4A/DDB1/DCAF1 E3 Complex	18
Acidic Enough for a Healthy Breath	18
Role of KCNK3 Dysfunction in Dasatinib-associated Pulmonary Arterial Hypertension and Endothelial Cell Dysfunction	17
Neuromedin U Induces Pulmonary ILC2 Activation via the NMUR1 Pathway during Acute Respiratory Syncytial Virus Infection	17
From Protein Folding to Precision Therapy: Surfactant Protein A in the Spotlight	17
Oxidized Phosphatidylcholines Trigger TRPA1 and Ryanodine Receptor–dependent Airway Smooth Muscle Contraction	17
A Unique CD27-IgD- B Cell Population in the Sputum of Severe Eosinophilic Asthma Associated with Airway Autoimmunity	17
Intermediary Role of Lung Alveolar Type 1 Cells in Epithelial Repair upon Sendai Virus Infection	17
Peripheral Blood Omics and Other Multiplex-based Systems in Pulmonary and Critical Care Medicine	17
Cell Culture Differentiation and Proliferation Conditions Influence the In Vitro Regeneration of the Human Airway Epithelium	17

Soluble E-Cadherin Contributes to Airway Inflammation in Severe Asthma	17
A Single-Cell RNA Sequencing Atlas of the Chronic Obstructive Pulmonary Disease Distal Lung to Predict Cell–Cell Communication	17
A Locus on Chromosome 15 Contributes to Acute Ozone-induced Lung Injury in Collaborative Cross Mice	17
Improving Mitochondrial Function in Viral Infection: Targeting Cellular Metabolism	16
Axl Mediates Resistance to Respiratory Syncytial Virus Infection Independent of Cell Attachment	16
Biomarkers of Fibrosis in Patients with COVID-19 One Year After Hospital Discharge: A Prospective Cohort Study	16
Chronic Alcohol Intake Compromises Lung Immunity by Altering Immunometabolism in Humans and Mouse Models	16
Calcium-Sensing Receptor Negative Allosteric Modulators Oppose Contraction of Mouse Airways	15
Alpha-1 Antitrypsin Deficiency: Does Increased Neutrophil Adhesion Contribute to Lung Damage?	15
Comparison of Droplet- and Microwell-based Methods to Analyze Cryopreserved Human BAL Cells by Single-Cell RNA Sequencing	15
An Antiviral Effect of Linoleic Acid Against Rhinovirus Infection	15
Airway Immune Signatures in Severe and Fatal Infection with COVID-19	15
Unveiling Organ Failure in the Critically Ill: Insights through the Metabolite Lens	15
Alveolar and Bone Marrow–derived Macrophages Differ in Metabolism and Glutamine Utilization	15
Demystifying Bitter Taste Receptor Relaxation of Airway Smooth Muscle	15
Therapeutic Potential of Sodium Houttuyfonate in Pulmonary Hypertension through Orai-Ca2+ Channels	15
Loss of Iron Regulatory Protein 2 Protects Mice from Lung Inflammation during Bronchoconstriction	15
Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development	15
Searching for an Animal Model with Clinical Features of Scleroderma	15
Sodium Houttuyfonate Alleviates Monocrotaline-induced Pulmonary Hypertension by Regulating Orai1 and Orai2	15
April Highlights/Papers by Junior Investigators/NIH News	15
TMPRSS11E-dward Scissorhands? Proteolysis Potentiates Lung Inflammation during Pathogen Insult	15
Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells	15
Prenatal LPS Exposure Promotes Allergic Airway Inflammation via Long Coding RNA NONMMUT033452.2, and Protein Binding Partner, Eef1D	14
Mitochondria-derived Vesicle Packaging as a Novel Therapeutic Mechanism in Pulmonary Hypertension	14
Tipping the Balance of Ubiquitination toward a Therapy for COVID-19	14
Redox-Dependent Activation of Lung Epithelial STAT3 Is Required for Inducible Protection against Bacterial Pneumonia	14
Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis	14
Recessive Mutations in CFAP74 Cause Primary Ciliary Dyskinesia with Normal Ciliary Ultrastructure	14
Pirfenidone Mitigates Transforming Growth Factor-β–induced Inflammation after Viral Infection	14
Multiomic Signatures of Chronic Beryllium Disease Bronchoalveolar Lavage Cells Relate to T-Cell Function and Innate Immunity	14
A New Methodology for the Oxygen Measurement in Lung Tissue of an Aged Ferret Model Proves Hypoxia during COVID-19	13
Does “Skippy” Wheeze? Evidence of Airway Remodeling in the Australian Kangaroo	13
Leveraging Microbial Symbiosis to Modulate Bronchopulmonary Dysplasia	13
Pulmonary and Nonpulmonary Sepsis Differentially Modulate Lung Immunity toward Secondary Bacterial Pneumonia: A Critical Role for Alveolar Macrophages	13
Chronic Obstructive Pulmonary Disease Airway Epithelial Cell–derived Extracellular Vesicles Spread Cellular Senescence via MicroRNA-34a	13
January Highlights/Papers by Junior Investigators/NIH News	13
DNA–Protein Kinase Catalytic Subunit as a Potential Target for Pulmonary Arterial Hypertension	13
February Highlights/Papers by Junior Investigators/NIH News	13
Cell Surface RNA Expression Modulates Alveolar Epithelial Function	13
Pulmonary Microvascular Endothelial Cells Support Alveolar Epithelial Growth via Bone Morphogenetic Protein 6 Secretion	13
HPS6 Deficiency Leads to Reduced Vacuolar-Type H+-ATPase and Impaired Biogenesis of Lamellar Bodies in Alveolar Type II Cells	13
A Novel Role for γδ T Cells in Protection Against Severe Melioidosis	13
A NEAT Discovery Hints at Altered Golgi Signaling in Lung Fibrosis	13
Human Airway Basal Cells Undergo Reversible Squamous Differentiation and Reshape Innate Immunity	12
Breath Markers of Oxidative Stress in Children with Severe Viral Lower Respiratory Tract Infection	12
July Highlights/Papers by Junior Investigators/NIH News	12
Circular RNA-Cacna1d Plays a Critical Role in Sepsis-induced Lung Injury by Sponging microRNA-185-5p	12
Enhanced Lyn Activity Causes Severe, Progressive Emphysema and Lung Cancer	12
Cytokine Regulation by Alpha-1 Antitrypsin Therapy: A Pathway Analysis of a Pilot Clinical Trial	12
SOX17 Prevents Endothelial–Mesenchymal Transition of Pulmonary Arterial Endothelial Cells in Pulmonary Hypertension through Mediating TGF-β/Smad2/3 Signaling	12
When Autophagy Fails: ATG7 Variants and Their Impact on Radiation Lung Injury	12
September Highlights/Papers by Junior Investigators/NIH News	12
Collagen 18A1/Endostatin Expression in the Progression of Right Ventricular Remodeling and Dysfunction in Pulmonary Arterial Hypertension	11
Dual Pigment Epithelium-derived Factor and Hepatocyte Growth Factor Overexpression: A New Therapy for Pulmonary Hypertension	11
A Redox-Shifted Fibroblast Subpopulation Emerges in the Fibrotic Lung	11
Mycobacterium tuberculosis Induces Warburg Metabolism in Human Alveolar Macrophages: A Transcriptomic Analysis	11
The Gut–Lung Axis: What’s below the Diaphragm Is Also Important	11
Multiresolution 3D Optical Mapping of Immune Cell Infiltrates in Mouse Asthmatic Lung	11
Does Chronic Obstructive Pulmonary Disease Originate from Different Cell Types?	11
Amphipathic Helical Peptide L37pA Protects against Lung Vascular Endothelial Dysfunction Caused by Truncated Oxidized Phospholipids via Antagonism with CD36 Receptor	11
Alveolar Epithelial Cell Dysfunction in Idiopathic Pulmonary Fibrosis Linked to Lipid Alterations: Therapeutic Implications	11
Epigenomic Dysregulation in Youth Vapers: Implications for Disease Risk Assessment	11
Kasugamycin Is a Novel Chitinase 1 Inhibitor with Strong Antifibrotic Effects on Pulmonary Fibrosis	11
Activated Clec4nhi Neutrophils Aggravate Lung Injury in an Endothelial IGFBP7-Dependent Manner	11
The RIPK3 Scaffold Regulates Lung Inflammation During Pseudomonas Aeruginosa Pneumonia	11
Switching On Gene Therapy for Allergic Rhinitis: The AAVITS Approach	10
Bubble Trouble: Epithelial Extracellular Vesicles and Their microRNA Mischief in Chronic Obstructive Pulmonary Disease	10
Monocytes: See One Queuing Local Adaptive Immune Responses to Respiratory Viruses	10
Transcriptomics Analysis Identifies the Decline in the Alveolar Type II Stem Cell Niche in Aged Human Lungs	10
Reply to Fujino et al. : Human Lung Cell Separation Strategies for Translational Research	10
Respiratory Epithelial Cell Surface Decoration Provides Defense against Bacterial Damage during Infection	10
Chronic Kidney Disease–associated Lung Injury Is Mediated by Phosphate-induced MAPK/AKT Signaling	10
Peripheral Transcriptome of Severe Sarcoidosis Involves Dysregulation of Multiple Immunologic Systems	10
June Highlights/Papers by Junior Investigators/NIH News	10
Cell Population–resolved Multiomics Atlas of the Developing Lung	10
A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis	10
Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine	10
Microenvironment Regulators of Metastasis Favor Lymphangioleiomyomatosis Cell Growth and Disease Progression	10
Unveiling an Important New Cell Type in the Lung: Microfold Cells	10

Single-Cell Profiling of Premature Neonate Airways Reveals a Continuum of Myeloid Differentiation	10
You Can’t Spell Shear without “She”: Mechanobiology and Sex Differences in Hypoxic Lung Disease	10
Lipids to the Rescue in Pulmonary Fibrosis: Biosynthesis, Bioenergetics, or Epigenetics?	10
One More Negative Regulator of AC6: S-Nitrosylation	9
Characteristics and Regulation of Human Eosinophil ETosis In Vitro	9
The Potential of Extracellular Microvesicle MicroRNAs in Precapillary Pulmonary Hypertension	9
Can ENaC “TIP” the Scales to Reduce Endothelial Reactive Oxygen Species and Vascular Leak during Pneumococcal Lung Injury?	9
Cystic Fibrosis: “Ionocyte Modulators”?	9
Fetal Tracheal Occlusion Correlates with Normalized YAP Expression and Alveolar Epithelial Differentiation in Congenital Diaphragmatic Hernia	9
Sectm1a Depletion Promotes Neutrophil Recruitment during Pneumococcal Pneumonia	9
LAM–CAM: In Vivo Model for Rapid Analysis of Lymphangioleiomyomatosis Tumor Formation and Inhibition	9
Engineering HMGB1-derived Peptides to Unravel Sex-Specific Mechanisms in Pulmonary Arterial Hypertension	9
“It’s a Trap”: Eosinophils Caught between Pro- and Anti-inflammatory Responses	9
May Highlights/Papers by Junior Investigators/NIH News	9
Mitochondrial Transfer Regulates Bioenergetics in Healthy and Chronic Obstructive Pulmonary Disease Airway Smooth Muscle	9
Reclaiming the Balance: Blocking Glutamine Uptake to Restrain Pulmonary Fibrosis	9
December Highlights/Papers by Junior Investigators/NIH News	9
Suppression of Allergic Asthma by Loss of Function of Miz1-mediated Th1 Skewing	9
Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Emphysema	9
Analysis of Aberrant Splicing Events and Gene Expression Outliers in Primary Ciliary Dyskinesia	9
Ventilator-Induced Lung Injury Promotes Inflammation Within the Pleural Cavity	9
A Functional Variant rs2122031 in ATG7 Is Associated with the Risk of Radiation Pneumonitis	9
Shear Stress Markedly Alters the Proteomic Response to Hypoxia in Human Pulmonary Endothelial Cells	9
Identification of Lymphangioleiomyomatosis-associated Serum MicroRNAs	9
On the Ultrastructure of Aberrant Basaloid Cells in Idiopathic Pulmonary Fibrosis	9
Increased Circulating Extracellular Superoxide Dismutase Attenuates Platelet–Neutrophil Interactions	9