Pharmacological Research

Article	Citations
Development status and prospects of international standardization of medical devices of Traditional Chinese Medicine	463
Editorial Board	429
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation	216
Natural HSP90 inhibitors as a potential therapeutic intervention in treating cancers: A comprehensive review	205
Therapeutic implications of sonic hedgehog pathway in metabolic disorders: Novel target for effective treatment	201
Drug-induced atrial fibrillation. A narrative review of a forgotten adverse effect	185
Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis	173
Corrigendum to ‘Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70′ [Pharmacol. Res. 100 (2015) 341–352]	166
Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020	162
Congenital diaphragmatic hernia increases the sensitivity of pulmonary arteries to nitric oxide	161
G-protein biased signaling agonists of Dopamine D3 receptor promote distinct activation patterns of ERK1/2	161
Time-dependent proteomics and drug response in expanding cancer cells	161
Molecular mechanisms underlying hepatoprotective activity of lutein in the context of intestinal failure-associated liver disease	153
An account on the history of pharmacology in Spain	152
Gut-vascular axis and postbiotics: The need for clear definitions and further research	149
Komagataella pastoris KM71H modulates neuroimmune and oxidative stress parameters in animal models of depression: A proposal for a new probiotic with antidepressant-like effect	143
Impact of Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer’s disease	140
The effect of tibolone treatment on lipid profile in women: A systematic review and dose-response meta-analysis of randomized controlled trials	134
Relevance of mitochondrial oxidative stress to arrhythmias: Innovative concepts to target treatments	134
Dual BET/HDAC inhibition to relieve neuropathic pain: Recent advances, perspectives, and future opportunities	132
Noncoding RNAs involved in DNA methylation and histone methylation, and acetylation in diabetic vascular complications	131
Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9	129
Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death	121
In vitro angiogenesis inhibition with selective compounds targeting the key glycolytic enzyme PFKFB3	121
Unraveling the roles of miRNAs in regulating epithelial-to-mesenchymal transition (EMT) in osteosarcoma	119

Chromatin factors: Ready to roll as biomarkers in metastatic colorectal cancer?	119
DNMT3a-mediated methylation of TCF21/hnRNPA1 aggravates hepatic fibrosis by regulating the NF-κB signaling pathway	116
Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein	113
Looking deeper into the findings of DARE-19: Failure or an open door to future success?	113
Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer	110
Echinatin inhibits the growth and metastasis of human osteosarcoma cells through Wnt/β-catenin and p38 signaling pathways	108
Hirsutine ameliorates hepatic and cardiac insulin resistance in high-fat diet-induced diabetic mice and in vitro models	107
Simultaneously blocking ANGPTL3 and CD47 prevents the progression of atherosclerosis through regulating lipid metabolism, macrophagic efferocytosis and lipid peroxidation	104
The function and therapeutic potential of transfer RNA-derived small RNAs in cardiovascular diseases: A review	103
Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales	101
Mitochondrial dysfunction and beneficial effects of mitochondria-targeted small peptide SS-31 in Diabetes Mellitus and Alzheimer’s disease	100
Piperlongumine synergistically enhances the antitumour activity of sorafenib by mediating ROS-AMPK activation and targeting CPSF7 in liver cancer	100
The specific deletion of cyclooxygenase-1 in megakaryocytes/platelets reduces intestinal polyposis in Apc mice	98
Response to letter to the editor: Letter by Chen et al. regarding article, “Assessment of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer's disease: A pop	97
Research progress on the interaction between oxidative stress and platelets: Another avenue for cancer?	96
Efficacy of vitamin D supplementation as an adjunct therapy for improving inflammatory and oxidative stress biomarkers: An umbrella meta-analysis	96
ARID1A is a coactivator of STAT5 that contributes to CD8+ T cell dysfunction and anti-PD-1 resistance in gastric cancer	94
Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression	90
Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer	89
Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway	88
The Role of Exosomes Derived from Various Sources in Facilitating the Healing of Chronic Refractory Wounds	87
Present and future antipsychotic drugs: A systematic review of the putative mechanisms of action for efficacy and a critical appraisal under a translational perspective	86
NAFLD-associated hepatocellular carcinoma (HCC) – A compelling case for repositioning of existing mTORc1 inhibitors	86
Progress in the development of modulators targeting Frizzleds	85
Polypharmacology: The science of multi-targeting molecules	84
Phloretin ameliorates diabetes-induced endothelial injury through AMPK-dependent anti-EndMT pathway	84
Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis	82
Dihydromyricetin improves DSS-induced colitis in mice via modulation of fecal-bacteria-related bile acid metabolism	82
Astaxanthin: A promising therapeutic agent for organ fibrosis	81
Cordycepin alleviated metabolic inflammation in Western diet-fed mice by targeting intestinal barrier integrity and intestinal flora	81
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy	80
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer	79
Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of JAK2 Via the JAK2-STAT3-PDL1	79
Targeting regulated cell death in aortic aneurysm and dissection therapy	78
Pragmatic diagnostic and therapeutic algorithms to optimize new potassium binder use in cardiorenal disease	77
Corrigendum to ‘Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein’ [Pharmacol. Res. 175 (2022) 105975]	77
Pharmacological targeting of HMGB-1 translocation: A potential therapeutic strategy for COVID-19	76
Editorial Board	75
The potential modulatory role of curcumin on renal epithelial-to-mesenchymal transition in renal diseases	74
Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma	74
Functional metabolomics revealed the dual-activation of cAMP-AMP axis is a novel therapeutic target of pancreatic cancer	74
Role of Angiopoietin-Tie axis in vascular and lymphatic systems and therapeutic interventions	73
The natural product berberine synergizes with osimertinib preferentially against MET-amplified osimertinib-resistant lung cancer via direct MET inhibition	73
Ginsenoside Ro prevents endothelial injury via promoting Epac1/AMPK- mediated mitochondria protection in early diabetic retinopathy	71
Multidisciplinary consensus on the diagnosis and management of patients with atypical Hemolytic Uremic Syndrome (complement-mediated TMA): recommendations from Italian scientific societies, patient as	71
DNA repair biomarkers to guide usage of combined PARP inhibitors and chemotherapy: A meta-analysis and systematic review	71
Targeting HDAC8 to ameliorate skeletal muscle differentiation in Duchenne muscular dystrophy	70
Regulation of nicotinic acetylcholine receptors by post-translational modifications	69
Resveratrol-mediated attenuation of superantigen-driven acute respiratory distress syndrome is mediated by microbiota in the lungs and gut	69
ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites	69

Combining liquid biopsy and radiomics for personalized treatment of lung cancer patients. State of the art and new perspectives	69
A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME	69
A copper nanocluster-based multifunctional nanoplatform for augmented chemo/chemodynamic/photodynamic combination therapy of breast cancer	69
Remote ischemic conditioning attenuates blood-brain barrier disruption after recombinant tissue plasminogen activator treatment via reducing PDGF-CC	68
Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models	68
Evaluation of the analgesic effect of ɑ-lipoic acid in treating pain disorders: A systematic review and meta-analysis of randomized controlled trials	67
The p53 pathway in vasculature revisited: A therapeutic target for pathological vascular remodeling?	67
Combining choline bitartrate and vitamin B12 ameliorates cognitive impairment in hypertensive elders with cognitive frailty	67
Lycorine improves peripheral nerve function by promoting Schwann cell autophagy via AMPK pathway activation and MMP9 downregulation in diabetic peripheral neuropathy	67
Metabolic disorders affecting the liver and heart: Therapeutic efficacy of miRNA-based therapies?	66
Pharmacological targeting of G protein-coupled receptor heteromers	66
Ferritin nanoconjugates guide trastuzumab brain delivery to promote an antitumor response in murine HER2 + breast cancer brain metastasis	66
Sailing south from regulations to strategies: Macau as a promising gateway for the export of proprietary Chinese medicines to ASEAN countries	66
Net clinical benefit of a reduced dose of DOACs in non-valvular atrial fibrillation: A meta-analysis of randomized trials	66
Blocking ANGPTL3 and CD47 impact on atherosclerosis-correspondence	64
Atrial fibrillation: Epigenetic aspects and role of sodium-glucose cotransporter 2 inhibitors	64
Corrigendum to “Deficiency in adiponectin exaggerates cigarette smoking exposure-induced cardiac contractile dysfunction: Role of autophagy” [Pharm. Res. 100 (2015) 175–89]	64
Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease	64
Expand available targets for CAR-T therapy to overcome tumor drug resistance based on the "Evolutionary Traps"	63
Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges	62
A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine	62
The major histocompatibility complex participates in Parkinson’s disease	62
Single-cell RNA sequencing highlights the roles of C1QB and NKG7 in the pancreatic islet immune microenvironment in type 1 diabetes mellitus	61
α1-adrenoceptor ligands inhibit chemokine receptor heteromerization partners of α1B/D-adrenoceptors via interference with heteromer formation	61
Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics	61
Profiling the impact of anti-human CD20 monoclonal antibodies on lymphocyte B cell subsets and their precursors in the bone marrow and in lymphoid tissues in an immunocompromised mouse engrafted with	61
Medical treatment of weight loss in children and adolescents with obesity	60
Pharmacological targeting of microglia dynamics in Alzheimer’s disease: Preclinical and clinical evidence	60
Elevated activity of plasma dipeptidyl peptidase 4 upon stress can be targeted to reverse tumor immunosuppression	59
Recent advances in glioma microenvironment-response nanoplatforms for phototherapy and sonotherapy	59
Targeted and cytotoxic inhibitors used in the treatment of lung cancers	59
Protein-polysaccharide interactions for the fabrication of bioactive-loaded nanocarriers: Chemical conjugates and physical complexes	58
Mitochondria as an important target of metformin: The mechanism of action, toxic and side effects, and new therapeutic applications	58
CircRNA in ocular neovascular diseases: Fundamental mechanism and clinical potential	58
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice	58
Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review	57
TAK1 blockade as a therapy for retinal neovascularization	57
IUPHAR Article: Psilocybin induces long-lasting effects via 5-HT2A receptors in mouse models of chronic pain	57
The action of curcumin against damage resulting from cerebral stroke: A systematic review	56
The complementary and alternative roles of elemene injection in cancer: An umbrella review	56
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression	56
Nasal accumulation and metabolism of Δ9-tetrahydrocannabinol following aerosol (‘vaping’) administration in an adolescent rat model	56
Hydrogen sulfide regulates the redox state of soluble guanylate cyclase in CSE-/- mice corpus cavernosum microcirculation	56
New therapeutic avenues in multiple sclerosis: Is there a place for gut microbiota-based treatments?	55
Hormesis: wound healing and fibroblasts	55
Dihydroartemisinin overcomes the resistance to osimertinib in EGFR-mutant non-small-cell lung cancer	55
Effects of exogenous melatonin supplementation on health outcomes: An umbrella review of meta-analyses based on randomized controlled trials	55
Hormesis: Wound healing and keratinocytes	55
Role of hypoxia in cellular senescence	55
Proneurogenic and neuroprotective effect of a multi strain probiotic mixture in a mouse model of acute inflammation: Involvement of the gut-brain axis	55
EGFR mutation mediates resistance to EGFR tyrosine kinase inhibitors in NSCLC: From molecular mechanisms to clinical research	55
IUPHAR editorial: Emerging targets for the treatment of pain: Moving towards non-addicting therapeutics and new preclinical directions	54
Commentary on “Apabetalone, a BET protein inhibitor, inhibits kidney damage in diabetes by preventing pyroptosis via modulating the P300/H3K27ac/PLK1 axis”	54
Targeting LRP6: A new strategy for cancer therapy	54
Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: A systematic review and meta-analysis of randomi	54
Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science	54
The role and potential mechanism of O-Glycosylation in gastrointestinal tumors	53
The α9α10 acetylcholine receptor: A non-neuronal nicotinic receptor	53
Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy	53
Beneficial effects of brown fat activation on top of PCSK9 inhibition with alirocumab on dyslipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice	53
The interplay of aging, sleep dysregulation, and mitochondrial dysfunction in metabolic and neurodegenerative diseases	53
Gut microbiota-driven metabolic alterations reveal the distinct pathogenicity of chemotherapy-induced cachexia in gastric cancer	53
(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice	52
Action and therapeutic targets of myosin light chain kinase, an important cardiovascular signaling mechanism	52
Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression	52
Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics	51
Understanding the habenula: A major node in circuits regulating emotion and motivation	51
Lipoxin-mediated signaling: ALX/FPR2 interaction and beyond	51
Ketogenic diet in children and adolescents: The effects on growth and nutritional status	51
Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect	51
Pleurotus eryngii improves postprandial glycaemia, hunger and fullness perception, and enhances ghrelin suppression in people with metabolically unhealthy obesity	51
Neutrophils as potential therapeutic targets for breast cancer	50
Zedoarondiol inhibits atherosclerosis by regulating monocyte migration and adhesion via CXCL12/CXCR4 pathway	50
Acetylcholinesterase inhibitor ameliorates doxorubicin-induced cardiotoxicity through reducing RIP1-mediated necroptosis	50
A panel of altered blood oxysterols in patients with mild cognitive impairment: A novel combined diagnostic marker	49
Potential of diterpenes as antidiabetic agents: Evidence from clinical and pre-clinical studies	49
Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome	49
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio	49
Systematic druggable genome-wide Mendelian randomization to identify therapeutic targets and dominant flora for ulcerative colitis	49
TRP channels in cancer: Therapeutic opportunities and research strategies	49

Corrigendum to “Ectopic expression of NKG7 enhances CAR-T function and improves the therapeutic efficacy in liquid and solid tumors” [Pharmacol. Res. 210 (2024) 107506]	48
A review of pharmacological and pharmacokinetic properties of Forsythiaside A	48
Nanotheranostics in cancer lymph node metastasis: The long road ahead	48
Dapagliflozin acutely improves kidney function in type 2 diabetes mellitus. The PRECARE study	48
Alternative splicing: A key regulator in T cell response and cancer immunotherapy	48
Long noncoding RNA p21 enhances autophagy to alleviate endothelial progenitor cells damage and promote endothelial repair in hypertension through SESN2/AMPK/TSC2 pathway	48
Application of carbon monoxide in kidney and heart transplantation: A novel pharmacological strategy for a broader use of suboptimal renal and cardiac grafts	47
Corrigendum to “A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME” [Pharmacol. Res. 181 (2022) 106269]	47
Mitochondria-targeted hydrogen sulfide donor reduces fatty liver and obesity in mice fed a high fat diet by inhibiting de novo lipogenesis and inflammation via mTOR/SREBP-1 and NF-κB signaling pathway	47
Leveraging HER2-targeted biparatopic antibodies in solid tumors	47
ER-organelle contacts: A signaling hub for neurological diseases	46
SNX17 protects the heart from doxorubicin-induced cardiotoxicity by modulating LMOD2 degradation	46
New therapies towards a better glycemic control in youths with type 1 diabetes	46
Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming	46
Role for the F-box proteins in heart diseases	46
Role of NSD1 as potential therapeutic target in tumor	46
Establishment of an inducible cell line for Hepatitis B virus genotype C2 and its pharmacological responses to interferons	46
Treating COVID-19 with NRICM101 and NRICM102 – Author’s reply 3	45
Therapeutic induction of energy metabolism reduces neural tissue damage and increases microglia activation in severe spinal cord injury	45
Special Issue Spanish Basic and Clinical Pharmacology	45
Game-changer in the fight against Huntington's disease: Cholesterol nanoparticles restore brain function in mice	44
Editorial Board	44
Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation	44
Acute coronary syndrome and lipid-lowering therapy in a realistic diagnostic-therapeutic care pathway	44
Efficacy and safety of Qingda granule versus valsartan capsule in Chinese grade 1 hypertensive patients with low-moderate risk: A randomized, double-blind, double dummy, non-inferiority, multi-center	44
Editorial Board	44
Garlic constituents for cancer prevention and therapy: From phytochemistry to novel formulations	43
IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics	43
Design of the distribution of iron oxide (Fe3O4) nano-particle drug in realistic cholangiocarcinoma model and the simulation of temperature increase during magnetic induction hyperthermia	43
Polyol pathway and redox balance in diabetes	43
MicroRNA-based therapeutics for inflammatory disorders of the microbiota-gut-brain axis	43
Regulation of glycolysis-derived L-lactate production in astrocytes rescues the memory deficits and Aβ burden in early Alzheimer’s disease models	43
Post-stroke administration of H2 relaxin reduces functional deficits, neuronal apoptosis and immune cell infiltration into the mouse brain	42
Elucidation of the anti-inflammatory mechanism of Er Miao San by integrative approach of network pharmacology and experimental verification	42
Functional significance of O-linked N-acetylglucosamine protein modification in regulating autophagy	42
Corrigendum to “Sugiol, a diterpenoid: Therapeutic actions and molecular pathways involved” Pharmacol. Res. 163 (2021) 105313	42
Anticancer potential of allicin: A review	42
The role of androgens in women's health and wellbeing	42
Kallistatin leads to cognition impairment via downregulating glutamine synthetase	42
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models	41
Letter to the editor regarding: “Cannabis and its constituents for cancer: history, biogenesis, chemistry, and pharmacological activities”	41
Mtnr1b deletion disrupts placental angiogenesis through the VEGF signaling pathway leading to fetal growth restriction	41
Activation of PKM2 metabolically controls fulminant liver injury via restoration of pyruvate and reactivation of CDK1	41
Gut Clostridium sporogenes-derived indole propionic acid suppresses osteoclast formation by activating pregnane X receptor	41
Clinical trials of orphan drugs in China over the decade 2012–2022: Opportunities and challenges	41
Paracetamol metabolism by endothelial cells – Potential mechanism underlying intravenous paracetamol-induced hypotension	41
The ketogenic diet modulates tumor-associated neutrophil polarization via the AMOT-YAP/TAZ axis to inhibit colorectal cancer progression	41
Corrigendum to “Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling” [Pharmacol. Res. 119 (2017) 72–88]	41
Editorial Board	41
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy	40
A hepatocellular carcinoma model with and without parenchymal liver damage that integrates technical and pathophysiological advantages for therapy testing	40
An ode to valproic acid: A letter to the editor	40
Diabetic retinopathy in the pediatric population: Pathophysiology, screening, current and future treatments	40
Breaking through the treatment desert of conventional mesothelin-targeted CAR-T cell therapy for malignant mesothelioma: A glimpse into the future	40
Targeting regulated cell death (RCD) with naturally derived sesquiterpene lactones in cancer therapy	40
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction	39
Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis	39
Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases	39
p53: A double-edged sword in tumor ferroptosis	39
Powering prescription: Mitochondria as “Living Drugs” – Definition, clinical applications, and industry advancements	39
Inhibition of long noncoding RNA Gm41724 alleviates pressure overload-induced cardiac fibrosis by regulating lamina-associated polypeptide 2α	39
HMGA2 regulation by miRNAs in cancer: Affecting cancer hallmarks and therapy response	39
ABCB1 limits brain exposure of the KRASG12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability	39
Crosstalk between extracellular vesicles and autophagy in cardiovascular pathophysiology	38
Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen- and prolactin-receptors in breast cancer	38
D-arabinose acts as antidepressant by activating the ACSS2-PPARγ/TFEB axis and CRTC1 transcription	38
Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges	38
Targeting systemic inflammation in metabolic disorders. A therapeutic candidate for the prevention of cardiovascular diseases?	38
Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway	38
Clinical experience with CTLA-4 blockade for cancer immunotherapy: From the monospecific monoclonal antibody ipilimumab to probodies and bispecific molecules targeting the tumor microenvironment	38
Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders	38
Circulating cytokines and risk of developing hypertension: A systematic review and meta-analysis	38
Crosstalk of miRNAs with signaling networks in bladder cancer progression: Therapeutic, diagnostic and prognostic functions	38
Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis	37
A novel approach to explore metabolic diseases: Neddylation	37
The potential role of mitochondria in the microbiota-gut-brain axis: Implications for brain health	37
SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-19	37
AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease	37
A review of KLF4 and inflammatory disease: Current status and future perspective	37
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes	37
The AIM2 inflammasome: A novel biomarker and target in cardiovascular disease	37
β-amyloid’s neurotoxic mechanisms as defined by in vitro microelectrode arrays: a review	36
Biological activities, Molecular mechanisms, and Clinical application of Naringin in Metabolic syndrome	36
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis	36
Corrigendum to “Anlotinib combined with osimertinib reverses acquired osimertinib resistance in NSCLC by targeting the c-MET/MYC/AXL axis” [Pharmacol. Res. 188 (2023) 106668]	36
Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis: In vitro and in vivo comparative study	36
ALOX5 inhibition protects against dopaminergic neurons undergoing ferroptosis	36
BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading	36
Editorial Board	36
Corrigendum to “GPR37 promotes cancer growth by binding to CDK6 and represents a new theranostic target in lung adenocarcinoma”[Pharmacol. Res. 183 (2022) 106389]	36
Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis	36
Medicinal Chemistry approach, pharmacology and neuroprotective benefits of CB2R modulators in neurodegenerative diseases	36
RNA methylation and cancer treatment	36
Heteromerization of dopaminergic receptors in the brain: Pharmacological implications	36
Corrigendum to “Modulation of the JAK/ERK/STAT signaling in melanocortin -induced inhibition of local and systemic responses to myocardial ischemia/reperfusion [Pharmacological Research 72 (2013) 1–8]	36