Pharmacological Research

Article	Citations
Editorial Board	290
Impact of Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer’s disease	266
Gut-vascular axis and postbiotics: The need for clear definitions and further research	254
An account on the history of pharmacology in Spain	227
NAFLD-associated hepatocellular carcinoma (HCC) – A compelling case for repositioning of existing mTORc1 inhibitors	210
Molecular mechanisms underlying hepatoprotective activity of lutein in the context of intestinal failure-associated liver disease	199
G-protein biased signaling agonists of Dopamine D3 receptor promote distinct activation patterns of ERK1/2	195
Corrigendum to ‘Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70′ [Pharmacol. Res. 100 (2015) 341–352]	188
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation	180
Drug-induced atrial fibrillation. A narrative review of a forgotten adverse effect	170
Decoding the Metabolic-immune Axis: Neutrophil glycolysis-driven tumor niche remodeling and its therapeutic exploitation	166
Time-dependent proteomics and drug response in expanding cancer cells	154
Response to letter to the editor: Letter by Chen et al. regarding article, “Assessment of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer's disease: A pop	153
Progress in the development of modulators targeting Frizzleds	152
Relevance of mitochondrial oxidative stress to arrhythmias: Innovative concepts to target treatments	150
Organ-targeted biomarkers of sepsis: A systematic review reveals the value of inflammation and lipid metabolic dysregulation	143
Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer	143
Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein	143
The function and therapeutic potential of transfer RNA-derived small RNAs in cardiovascular diseases: A review	136
Chromatin factors: Ready to roll as biomarkers in metastatic colorectal cancer?	136
Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death	132
Molecular mechanisms of pyroptosis in non-alcoholic steatohepatitis and feasible diagnosis and treatment strategies	130
Paeoniflorin as a potential therapeutic agent for cerebrovascular diseases: A comprehensive review	130
Congenital diaphragmatic hernia increases the sensitivity of pulmonary arteries to nitric oxide	129
Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression	122

Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis	117
ARID1A is a coactivator of STAT5 that contributes to CD8+ T cell dysfunction and anti-PD-1 resistance in gastric cancer	115
The specific deletion of cyclooxygenase-1 in megakaryocytes/platelets reduces intestinal polyposis in Apc mice	114
Therapeutic implications of sonic hedgehog pathway in metabolic disorders: Novel target for effective treatment	113
Sex differences in the weight response to GLP-1RA in people with type 2 diabetes. A long-term longitudinal real-world study	112
Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway	112
Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD	112
Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales	111
Piperlongumine synergistically enhances the antitumour activity of sorafenib by mediating ROS-AMPK activation and targeting CPSF7 in liver cancer	110
Cordycepin alleviated metabolic inflammation in Western diet-fed mice by targeting intestinal barrier integrity and intestinal flora	110
Astaxanthin: A promising therapeutic agent for organ fibrosis	108
Natural HSP90 inhibitors as a potential therapeutic intervention in treating cancers: A comprehensive review	106
Simultaneously blocking ANGPTL3 and CD47 prevents the progression of atherosclerosis through regulating lipid metabolism, macrophagic efferocytosis and lipid peroxidation	106
The role of exosomes derived from various sources in facilitating the healing of chronic refractory wounds	105
Echinatin inhibits the growth and metastasis of human osteosarcoma cells through Wnt/β-catenin and p38 signaling pathways	102
Combined effects of clonal hematopoiesis of indeterminate potential and P2Y12 inhibitors on outcomes of patients with ST-segment elevation myocardial infarction: A prospective study	102
Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9	102
Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis	101
Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of JAK2 Via the JAK2-STAT3-PDL1	100
Hirsutine ameliorates hepatic and cardiac insulin resistance in high-fat diet-induced diabetic mice and in vitro models	98
Research progress on the interaction between oxidative stress and platelets: Another avenue for cancer?	95
Efficacy of vitamin D supplementation as an adjunct therapy for improving inflammatory and oxidative stress biomarkers: An umbrella meta-analysis	94
Targeting regulated cell death in aortic aneurysm and dissection therapy	94
Phloretin ameliorates diabetes-induced endothelial injury through AMPK-dependent anti-EndMT pathway	93
Spatial proteomic profiling reveals conserved prognostic immune microenvironment features across molecular subtypes in small cell lung cancer	92
Protective effect and mechanisms of puerarin in metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis of animal studies	91
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy	89
Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020	87
Polypharmacology: The science of multi-targeting molecules	86
Present and future antipsychotic drugs: A systematic review of the putative mechanisms of action for efficacy and a critical appraisal under a translational perspective	86
DNMT3a-mediated methylation of TCF21/hnRNPA1 aggravates hepatic fibrosis by regulating the NF-κB signaling pathway	85
Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer	85
Blocking ANGPTL3 and CD47 impact on atherosclerosis-correspondence	84
Corrigendum to ‘Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein’ [Pharmacol. Res. 175 (2022) 105975]	84
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer	84
Sailing south from regulations to strategies: Macau as a promising gateway for the export of proprietary Chinese medicines to ASEAN countries	83
Hydrogen sulfide regulates the redox state of soluble guanylate cyclase in CSE-/- mice corpus cavernosum microcirculation	82
Multidisciplinary consensus on the diagnosis and management of patients with atypical Hemolytic Uremic Syndrome (complement-mediated TMA): Recommendations from Italian scientific societies, patient as	82
Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease	82
Elevated activity of plasma dipeptidyl peptidase 4 upon stress can be targeted to reverse tumor immunosuppression	82
WITHDRAWN: Red blood cell-derived extracellular vesicles deliver NUP85 siRNA to alleviate MASLD through downregulating SLC27A1/PPAR-γ in hepatocyte	81
Targeted and cytotoxic inhibitors used in the treatment of lung cancers	80
AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy	79
Profiling the impact of anti-human CD20 monoclonal antibodies on lymphocyte B cell subsets and their precursors in the bone marrow and in lymphoid tissues in an immunocompromised mouse engrafted with	78
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice	78
Revisiting the renin-angiotensin-aldosterone system in the eye: Mechanistic insights and pharmacological targets	77
Net clinical benefit of a reduced dose of DOACs in non-valvular atrial fibrillation: A meta-analysis of randomized trials	77
Editorial Board	77
Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models	76
Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma	75

Pragmatic diagnostic and therapeutic algorithms to optimize new potassium binder use in cardiorenal disease	75
Corrigendum to “Deficiency in adiponectin exaggerates cigarette smoking exposure-induced cardiac contractile dysfunction: Role of autophagy” [Pharm. Res. 100 (2015) 175–89]	75
Combining choline bitartrate and vitamin B12 ameliorates cognitive impairment in hypertensive elders with cognitive frailty	74
Expand available targets for CAR-T therapy to overcome tumor drug resistance based on the "Evolutionary Traps"	73
The action of curcumin against damage resulting from cerebral stroke: A systematic review	73
α1-adrenoceptor ligands inhibit chemokine receptor heteromerization partners of α1B/D-adrenoceptors via interference with heteromer formation	73
Pharmacological targeting of HMGB-1 translocation: A potential therapeutic strategy for COVID-19	72
Pharmacological targeting of microglia dynamics in Alzheimer’s disease: Preclinical and clinical evidence	72
Nasal accumulation and metabolism of Δ9-tetrahydrocannabinol following aerosol (‘vaping’) administration in an adolescent rat model	72
IUPHAR Article: Psilocybin induces long-lasting effects via 5-HT2A receptors in mouse models of chronic pain	72
The major histocompatibility complex participates in Parkinson’s disease	72
Single-cell RNA sequencing highlights the roles of C1QB and NKG7 in the pancreatic islet immune microenvironment in type 1 diabetes mellitus	72
ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites	71
Metabolic disorders affecting the liver and heart: Therapeutic efficacy of miRNA-based therapies?	71
Medical treatment of weight loss in children and adolescents with obesity	71
Remote ischemic conditioning attenuates blood-brain barrier disruption after recombinant tissue plasminogen activator treatment via reducing PDGF-CC	69
Regulation of nicotinic acetylcholine receptors by post-translational modifications	69
TAK1 blockade as a therapy for retinal neovascularization	69
CircRNA in ocular neovascular diseases: Fundamental mechanism and clinical potential	69
A copper nanocluster-based multifunctional nanoplatform for augmented chemo/chemodynamic/photodynamic combination therapy of breast cancer	69
Lycorine improves peripheral nerve function by promoting Schwann cell autophagy via AMPK pathway activation and MMP9 downregulation in diabetic peripheral neuropathy	68
Sirtuin3 attenuates pressure overload-induced pathological myocardial remodeling by inhibiting cardiomyocyte cuproptosis	68
Ferritin nanoconjugates guide trastuzumab brain delivery to promote an antitumor response in murine HER2 + breast cancer brain metastasis	67
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression	67
The complementary and alternative roles of elemene injection in cancer: An umbrella review	67
Pharmacological targeting of G protein-coupled receptor heteromers	67
Role of Angiopoietin-Tie axis in vascular and lymphatic systems and therapeutic interventions	66
Recent advances in glioma microenvironment-response nanoplatforms for phototherapy and sonotherapy	66
Ginsenoside Ro prevents endothelial injury via promoting Epac1/AMPK- mediated mitochondria protection in early diabetic retinopathy	66
Functional metabolomics revealed the dual-activation of cAMP-AMP axis is a novel therapeutic target of pancreatic cancer	66
Evaluation of the analgesic effect of ɑ-lipoic acid in treating pain disorders: A systematic review and meta-analysis of randomized controlled trials	65
Atrial fibrillation: Epigenetic aspects and role of sodium-glucose cotransporter 2 inhibitors	64
Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics	63
DNA repair biomarkers to guide usage of combined PARP inhibitors and chemotherapy: A meta-analysis and systematic review	63
Hormesis: wound healing and fibroblasts	62
Mitochondria as an important target of metformin: The mechanism of action, toxic and side effects, and new therapeutic applications	62
The natural product berberine synergizes with osimertinib preferentially against MET-amplified osimertinib-resistant lung cancer via direct MET inhibition	62
Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges	61
Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review	61
A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME	60
Astrocytic connexin43 in the medial prefrontal cortex regulates depressive- and anxiety-like behaviors via ATP release	60
Hormesis: Wound healing and keratinocytes	60
Protein-polysaccharide interactions for the fabrication of bioactive-loaded nanocarriers: Chemical conjugates and physical complexes	60
A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine	60
IUPHAR editorial: Emerging targets for the treatment of pain: Moving towards non-addicting therapeutics and new preclinical directions	59
Commentary on “Apabetalone, a BET protein inhibitor, inhibits kidney damage in diabetes by preventing pyroptosis via modulating the P300/H3K27ac/PLK1 axis”	59
Role of hypoxia in cellular senescence	59
Editorial Board	58
Corrigendum to “Ectopic expression of NKG7 enhances CAR-T function and improves the therapeutic efficacy in liquid and solid tumors” [Pharmacol. Res. 210 (2024) 107506]	58
Corrigendum to “Paclitaxel-Ang-2-functionalized bionic mesoporous selenium nanoparticles for targeted therapy of glioma” [Pharmacol. Res. 216 (2025) 107783]	57
Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation	57
The interplay of aging, sleep dysregulation, and mitochondrial dysfunction in metabolic and neurodegenerative diseases	57
Targeting LRP6: A new strategy for cancer therapy	56
MicroRNA-based therapeutics for inflammatory disorders of the microbiota-gut-brain axis	56
Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science	56
Special Issue Spanish Basic and Clinical Pharmacology	55
Editorial Board	55
MAO inhibitors for treatment-resistant depression: Bringing an updated perspective on pioneering drugs	55
New therapies towards a better glycemic control in youths with type 1 diabetes	55
Treating COVID-19 with NRICM101 and NRICM102 – Author’s reply 3	54
The α9α10 acetylcholine receptor: A non-neuronal nicotinic receptor	54
Editorial Board	54
Efficacy and safety of Qingda granule versus valsartan capsule in Chinese grade 1 hypertensive patients with low-moderate risk: A randomized, double-blind, double dummy, non-inferiority, multi-center	54
Corrigendum to “A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME” [Pharmacol. Res. 181 (2022) 106269]	54
Game-changer in the fight against Huntington's disease: Cholesterol nanoparticles restore brain function in mice	54
Establishment of an inducible cell line for Hepatitis B virus genotype C2 and its pharmacological responses to interferons	54
IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics	54
Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy	53
Effects of exogenous melatonin supplementation on health outcomes: An umbrella review of meta-analyses based on randomized controlled trials	53
Functional significance of O-linked N-acetylglucosamine protein modification in regulating autophagy	53
Leveraging HER2-targeted biparatopic antibodies in solid tumors	52
Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome	52
Therapeutical peptides – Rapidly developing pharmaceutical landscape	52
Systematic druggable genome-wide Mendelian randomization to identify therapeutic targets and dominant flora for ulcerative colitis	52
Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: A systematic review and meta-analysis of randomi	51
Post-stroke administration of H2 relaxin reduces functional deficits, neuronal apoptosis and immune cell infiltration into the mouse brain	51
Perturbations of CB1 receptor signalling during adolescence impair cortical myelination in female rats	51
Mitochondria-targeted hydrogen sulfide donor reduces fatty liver and obesity in mice fed a high fat diet by inhibiting de novo lipogenesis and inflammation via mTOR/SREBP-1 and NF-κB signaling pathway	51
Cannabidiol and Beta-Caryophyllene: Chronic inflammatory pain	50
TRP channels in cancer: Therapeutic opportunities and research strategies	50

Polyol pathway and redox balance in diabetes	50
Alternative splicing: A key regulator in T cell response and cancer immunotherapy	50
A panel of altered blood oxysterols in patients with mild cognitive impairment: A novel combined diagnostic marker	50
Adaptive immunity in osteoarthritis: Mechanisms and opportunities for regulatory T-cell–targeted therapy	50
Gut microbiota-driven metabolic alterations reveal the distinct pathogenicity of chemotherapy-induced cachexia in gastric cancer	50
Dapagliflozin acutely improves kidney function in type 2 diabetes mellitus. The PRECARE study	50
Regulation of glycolysis-derived L-lactate production in astrocytes rescues the memory deficits and Aβ burden in early Alzheimer’s disease models	49
Design of the distribution of iron oxide (Fe3O4) nano-particle drug in realistic cholangiocarcinoma model and the simulation of temperature increase during magnetic induction hyperthermia	49
Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics	49
Potential of diterpenes as antidiabetic agents: Evidence from clinical and pre-clinical studies	49
New therapeutic avenues in multiple sclerosis: Is there a place for gut microbiota-based treatments?	48
Neutrophils as potential therapeutic targets for breast cancer	48
ER-organelle contacts: A signaling hub for neurological diseases	48
Lipoxin-mediated signaling: ALX/FPR2 interaction and beyond	48
Nanotheranostics in cancer lymph node metastasis: The long road ahead	48
Zedoarondiol inhibits atherosclerosis by regulating monocyte migration and adhesion via CXCL12/CXCR4 pathway	48
Gut microbiota and well-being: A comprehensive summary of the special issue	47
Ferroportin 1 depletion in neural stem cells promotes hippocampal neurogenesis and cognitive function in mice	47
KV11.1 (hERG1)-centered macromolecular membrane complexes regulate proliferation in B cell lymphomas and constitute novel pharmacological targets	47
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio	47
Pleurotus eryngii improves postprandial glycaemia, hunger and fullness perception, and enhances ghrelin suppression in people with metabolically unhealthy obesity	46
Therapeutic induction of energy metabolism reduces neural tissue damage and increases microglia activation in severe spinal cord injury	46
Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming	46
Ketogenic diet in children and adolescents: The effects on growth and nutritional status	46
Action and therapeutic targets of myosin light chain kinase, an important cardiovascular signaling mechanism	46
Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression	46
Hv1 channel in immune cells and pharmacology	45
Anticancer potential of allicin: A review	45
The role and potential mechanism of O-Glycosylation in gastrointestinal tumors	45
Elucidation of the anti-inflammatory mechanism of Er Miao San by integrative approach of network pharmacology and experimental verification	44
Garlic constituents for cancer prevention and therapy: From phytochemistry to novel formulations	44
Understanding the habenula: A major node in circuits regulating emotion and motivation	44
Role for the F-box proteins in heart diseases	44
The potential role of mitochondria in the microbiota-gut-brain axis: Implications for brain health	43
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction	43
A hepatocellular carcinoma model with and without parenchymal liver damage that integrates technical and pathophysiological advantages for therapy testing	43
A novel approach to explore metabolic diseases: Neddylation	43
Powering prescription: Mitochondria as “Living Drugs” – Definition, clinical applications, and industry advancements	43
Breaking through the treatment desert of conventional mesothelin-targeted CAR-T cell therapy for malignant mesothelioma: A glimpse into the future	43
Stem cells therapy in neurodegenerative and neuroimmune diseases: Current status of treatments and future prospects	43
p53: A double-edged sword in tumor ferroptosis	43
Kallistatin leads to cognition impairment via downregulating glutamine synthetase	43
Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges	42
Ginsenoside Re binds Drp1 Leu94 across species to restore mitochondrial homeostasis via Atg1/ULK1-dependent fission-mitophagy coupling in age-related degeneration	42
The ketogenic diet modulates tumor-associated neutrophil polarization via the AMOT-YAP/TAZ axis to inhibit colorectal cancer progression	42
Circulating cytokines and risk of developing hypertension: A systematic review and meta-analysis	42
A review of KLF4 and inflammatory disease: Current status and future perspective	42
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes	41
Clinical experience with CTLA-4 blockade for cancer immunotherapy: From the monospecific monoclonal antibody ipilimumab to probodies and bispecific molecules targeting the tumor microenvironment	41
Clinical trials of orphan drugs in China over the decade 2012–2022: Opportunities and challenges	41
An ode to valproic acid: A letter to the editor	41
Editorial Board	41
Corrigendum to “Sugiol, a diterpenoid: Therapeutic actions and molecular pathways involved” Pharmacol. Res. 163 (2021) 105313	41
Diabetic retinopathy in the pediatric population: Pathophysiology, screening, current and future treatments	40
Inhibition of long noncoding RNA Gm41724 alleviates pressure overload-induced cardiac fibrosis by regulating lamina-associated polypeptide 2α	40
AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease	40
Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis	40
Crosstalk of miRNAs with signaling networks in bladder cancer progression: Therapeutic, diagnostic and prognostic functions	40
D-arabinose acts as antidepressant by activating the ACSS2-PPARγ/TFEB axis and CRTC1 transcription	40
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models	40
Gut microbiota-derived metabolite phenylacetylglutamine in cardiovascular and metabolic diseases	40
β-amyloid’s neurotoxic mechanisms as defined by in vitro microelectrode arrays: a review	40
Targeting regulated cell death (RCD) with naturally derived sesquiterpene lactones in cancer therapy	39
Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis: In vitro and in vivo comparative study	39
Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases	39
Targeting systemic inflammation in metabolic disorders. A therapeutic candidate for the prevention of cardiovascular diseases?	39
Biological activities, Molecular mechanisms, and Clinical application of Naringin in Metabolic syndrome	39
Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders	39
ABCB1 limits brain exposure of the KRASG12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability	39
Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen- and prolactin-receptors in breast cancer	39
ALOX5 inhibition protects against dopaminergic neurons undergoing ferroptosis	38
Paracetamol metabolism by endothelial cells – Potential mechanism underlying intravenous paracetamol-induced hypotension	38
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy	38
Gut Clostridium sporogenes-derived indole propionic acid suppresses osteoclast formation by activating pregnane X receptor	38
Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis	38
Mtnr1b deletion disrupts placental angiogenesis through the VEGF signaling pathway leading to fetal growth restriction	38
HMGA2 regulation by miRNAs in cancer: Affecting cancer hallmarks and therapy response	38
Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis	38
RNA methylation and cancer treatment	37
Corrigendum to “GPR37 promotes cancer growth by binding to CDK6 and represents a new theranostic target in lung adenocarcinoma”[Pharmacol. Res. 183 (2022) 106389]	37
Interleukin-11: A central integrative hub driving pathological progression from pulmonary inflammation and fibrosis to cancer	37
Targeted gut microbiome therapy: Applications and prospects of probiotics, fecal microbiota transplantation and natural products in the management of type 2 diabetes	37
Ginkgolide B targets and inhibits creatine kinase B to regulate the CCT/TRiC-SK1 axis and exerts pro-angiogenic activity in middle cerebral artery occlusion mice	37
Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway	37
Correspondence “Validation of fermentation techniques for prebiotic impact on gut microbiota”	37
Corrigendum to “Modulation of the JAK/ERK/STAT signaling in melanocortin -induced inhibition of local and systemic responses to myocardial ischemia/reperfusion [Pharmacological Research 72 (2013) 1–8]	37
Glutamine deprivation confers immunotherapy resistance by inhibiting IFN-γ signaling in cancer cells	37
Corrigendum to “Anlotinib combined with osimertinib reverses acquired osimertinib resistance in NSCLC by targeting the c-MET/MYC/AXL axis” [Pharmacol. Res. 188 (2023) 106668]	37
Dual role of the nasal microbiota in neurological diseases—An unignorable risk factor or a potential therapy carrier	37
The AIM2 inflammasome: A novel biomarker and target in cardiovascular disease	37
Targeting EVA1B in breast cancer: New avenues for precision oncology	37
Novel targets for treating neurodegenerative diseases: The PKM2-STAT3-hnRNPA1 feedback loop	37
Timely treatment and higher compliance to traditional Chinese medicine: New influencing factors for reducing severe COVID-19 based on retrospective cohorts in 2020 and 2021	37
Cardiomyocytes, cardiac endothelial cells and fibroblasts contribute to anthracycline-induced cardiac injury through RAS-homologous small GTPases RAC1 and CDC42	37
S-glutathionylation in cancer: from fundamental mechanisms to clinical applications	37