Pharmacological Research

Article	Citations
Impact of Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer’s disease	366
Editorial Board	365
Response to letter to the editor: Letter by Chen et al. regarding article, “Assessment of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer's disease: A pop	269
Progress in the development of modulators targeting Frizzleds	261
Corrigendum to ‘Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70′ [Pharmacol. Res. 100 (2015) 341–352]	247
An account on the history of pharmacology in Spain	235
Chromatin factors: Ready to roll as biomarkers in metastatic colorectal cancer?	223
ARID1A is a coactivator of STAT5 that contributes to CD8+ T cell dysfunction and anti-PD-1 resistance in gastric cancer	217
Discovery, development, and characterization of potent and selective USP11 inhibitors	204
Corrigendum to “Impaired PARP1-dependent DNA repair in MORC2 mutations drives axonal degeneration in Charcot-Marie-Tooth disease subtype 2Z and spinal muscular atrophy-like neuromotor disorders” [Phar	201
Gut-vascular axis and postbiotics: The need for clear definitions and further research	180
Rapid 64Cu radiolabeling and in vivo evaluation of DSPE–NODAGA liposomes in a murine mammary tumor model	170
Combined effects of clonal hematopoiesis of indeterminate potential and P2Y12 inhibitors on outcomes of patients with ST-segment elevation myocardial infarction: A prospective study	168
Time-dependent proteomics and drug response in expanding cancer cells	165
Molecular mechanisms underlying hepatoprotective activity of lutein in the context of intestinal failure-associated liver disease	164
The function and therapeutic potential of transfer RNA-derived small RNAs in cardiovascular diseases: A review	156
Chronic caffeine consumption prevents obesity-induced cognitive and memory impairments by reducing neuroinflammation and enhancing neuronal activity in the hippocampus	152
Molecular mechanisms of pyroptosis in non-alcoholic steatohepatitis and feasible diagnosis and treatment strategies	149
NAFLD-associated hepatocellular carcinoma (HCC) – A compelling case for repositioning of existing mTORc1 inhibitors	146
Protective effect and mechanisms of puerarin in metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis of animal studies	142
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation	135
Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death	127
Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9	127
Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020	125
DNMT3a-mediated methylation of TCF21/hnRNPA1 aggravates hepatic fibrosis by regulating the NF-κB signaling pathway	124

Drug-induced atrial fibrillation. A narrative review of a forgotten adverse effect	123
Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of JAK2 Via the JAK2-STAT3-PDL1	121
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer	115
Organ-targeted biomarkers of sepsis: A systematic review reveals the value of inflammation and lipid metabolic dysregulation	115
Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway	113
Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer	113
Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression	112
Decoding the Metabolic-immune Axis: Neutrophil glycolysis-driven tumor niche remodeling and its therapeutic exploitation	107
Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis	106
The specific deletion of cyclooxygenase-1 in megakaryocytes/platelets reduces intestinal polyposis in Apc mice	106
Congenital diaphragmatic hernia increases the sensitivity of pulmonary arteries to nitric oxide	105
Spatial proteomic profiling reveals conserved prognostic immune microenvironment features across molecular subtypes in small cell lung cancer	104
Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD	103
Bridging appetite and emotional dynamics: the oxytocinergic system as a therapeutic axis in feeding and eating disorders	100
Simultaneously blocking ANGPTL3 and CD47 prevents the progression of atherosclerosis through regulating lipid metabolism, macrophagic efferocytosis and lipid peroxidation	100
The immunomodulatory role of vitamins in tumor: Mechanisms and therapeutic implications	95
Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales	94
Targeting pulmonary vascular–alveolar coupling in bronchopulmonary dysplasia: Therapeutic mechanisms and translational prospects of extracellular vesicle-based drug delivery	94
Efficacy of vitamin D supplementation as an adjunct therapy for improving inflammatory and oxidative stress biomarkers: An umbrella meta-analysis	94
Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer	93
Sex differences in the weight response to GLP-1RA in people with type 2 diabetes. A long-term longitudinal real-world study	93
Paeoniflorin as a potential therapeutic agent for cerebrovascular diseases: A comprehensive review	92
Fig-derived exosome-like nanoparticles attenuating bone metastasis of breast cancer through establishing an anti-tumor microenvironment	91
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy	91
Research progress on the interaction between oxidative stress and platelets: Another avenue for cancer?	90
Astaxanthin: A promising therapeutic agent for organ fibrosis	90
The role of exosomes derived from various sources in facilitating the healing of chronic refractory wounds	90
Single-cell RNA sequencing highlights the roles of C1QB and NKG7 in the pancreatic islet immune microenvironment in type 1 diabetes mellitus	89
Blocking ANGPTL3 and CD47 impact on atherosclerosis-correspondence	89
Echinatin inhibits the growth and metastasis of human osteosarcoma cells through Wnt/β-catenin and p38 signaling pathways	89
Expand available targets for CAR-T therapy to overcome tumor drug resistance based on the "Evolutionary Traps"	88
Profiling the impact of anti-human CD20 monoclonal antibodies on lymphocyte B cell subsets and their precursors in the bone marrow and in lymphoid tissues in an immunocompromised mouse engrafted with	88
Editorial Board	87
Pragmatic diagnostic and therapeutic algorithms to optimize new potassium binder use in cardiorenal disease	85
Pharmacological targeting of HMGB-1 translocation: A potential therapeutic strategy for COVID-19	85
Hydrogen sulfide regulates the redox state of soluble guanylate cyclase in CSE-/- mice corpus cavernosum microcirculation	84
Atrial fibrillation: Epigenetic aspects and role of sodium-glucose cotransporter 2 inhibitors	84
Sailing south from regulations to strategies: Macau as a promising gateway for the export of proprietary Chinese medicines to ASEAN countries	84
Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges	84
A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine	83
The complementary and alternative roles of elemene injection in cancer: An umbrella review	83
The major histocompatibility complex participates in Parkinson’s disease	83
Hormesis: wound healing and fibroblasts	83
Fei-Yan-Qing-Hua decoction inhibits influenza viral replication by enhancing NK cell maturation and activation through the upregulation of JAK/STAT/T-bet signalling axis	83
α1-adrenoceptor ligands inhibit chemokine receptor heteromerization partners of α1B/D-adrenoceptors via interference with heteromer formation	82
Corrigendum to “Deficiency in adiponectin exaggerates cigarette smoking exposure-induced cardiac contractile dysfunction: Role of autophagy” [Pharm. Res. 100 (2015) 175–89]	82
Nasal accumulation and metabolism of Δ9-tetrahydrocannabinol following aerosol (‘vaping’) administration in an adolescent rat model	79
Corrigendum to ‘Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein’ [Pharmacol. Res. 175 (2022) 105975]	79
Pharmacological targeting of microglia dynamics in Alzheimer’s disease: Preclinical and clinical evidence	79
WITHDRAWN: Red blood cell-derived extracellular vesicles deliver NUP85 siRNA to alleviate MASLD through downregulating SLC27A1/PPAR-γ in hepatocyte	79

Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics	78
Revisiting the renin-angiotensin-aldosterone system in the eye: Mechanistic insights and pharmacological targets	78
TAK1 blockade as a therapy for retinal neovascularization	77
Gut microbiota and their metabolites in stroke: From mechanistic study toward therapeutic perspectives	77
Remote ischemic conditioning attenuates blood-brain barrier disruption after recombinant tissue plasminogen activator treatment via reducing PDGF-CC	77
Targeted and cytotoxic inhibitors used in the treatment of lung cancers	77
Ginsenoside Ro prevents endothelial injury via promoting Epac1/AMPK- mediated mitochondria protection in early diabetic retinopathy	76
A copper nanocluster-based multifunctional nanoplatform for augmented chemo/chemodynamic/photodynamic combination therapy of breast cancer	76
Elevated activity of plasma dipeptidyl peptidase 4 upon stress can be targeted to reverse tumor immunosuppression	75
Regulation of nicotinic acetylcholine receptors by post-translational modifications	75
Multidisciplinary consensus on the diagnosis and management of patients with atypical Hemolytic Uremic Syndrome (complement-mediated TMA): Recommendations from Italian scientific societies, patient as	74
CircRNA in ocular neovascular diseases: Fundamental mechanism and clinical potential	73
Combining choline bitartrate and vitamin B12 ameliorates cognitive impairment in hypertensive elders with cognitive frailty	73
Astrocytic connexin43 in the medial prefrontal cortex regulates depressive- and anxiety-like behaviors via ATP release	73
Medical treatment of weight loss in children and adolescents with obesity	73
Role of hypoxia in cellular senescence	72
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression	71
TSPO-mediated mitochondrial retrograde signaling primes the microglial NLRP3 inflammasome	71
Purinosomes and mitochondria: Dynamic interactomes at the crossroads of metabolism, cell structure, and disease	70
Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease	70
Metabolic disorders affecting the liver and heart: Therapeutic efficacy of miRNA-based therapies?	70
Crosstalk mechanisms among gut microbiota, novel programmed cell death, and macrophage polarization	70
Ferritin nanoconjugates guide trastuzumab brain delivery to promote an antitumor response in murine HER2 + breast cancer brain metastasis	69
Pharmacological targeting of G protein-coupled receptor heteromers	68
Functional metabolomics revealed the dual-activation of cAMP-AMP axis is a novel therapeutic target of pancreatic cancer	68
Beyond the HPA axis: Synaptic circuits of PVNCRH neurons in stress-related psychiatric disorders	68
The action of curcumin against damage resulting from cerebral stroke: A systematic review	67
AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy	67
Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma	66
Efficacy of Sativex® on pain, spasticity, and disability in patients with multiple sclerosis: A systematic review and meta-analysis	65
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice	65
Hormesis: Wound healing and keratinocytes	64
Sirtuin3 attenuates pressure overload-induced pathological myocardial remodeling by inhibiting cardiomyocyte cuproptosis	64
Role of Angiopoietin-Tie axis in vascular and lymphatic systems and therapeutic interventions	64
The therapeutic potential of puerarin on diabetic kidney disease: Focus on molecular mechanisms and future perspectives	64
IUPHAR editorial: Emerging targets for the treatment of pain: Moving towards non-addicting therapeutics and new preclinical directions	64
DNA repair biomarkers to guide usage of combined PARP inhibitors and chemotherapy: A meta-analysis and systematic review	64
IUPHAR Article: Psilocybin induces long-lasting effects via 5-HT2A receptors in mouse models of chronic pain	64
Commentary on “Apabetalone, a BET protein inhibitor, inhibits kidney damage in diabetes by preventing pyroptosis via modulating the P300/H3K27ac/PLK1 axis”	63
Editorial Board	62
Zedoarondiol inhibits atherosclerosis by regulating monocyte migration and adhesion via CXCL12/CXCR4 pathway	62
Plumbagin ameliorates multiple sclerosis by inducing DDX3X-mediated stress granule assembly in mice	61
TRP channels in cancer: Therapeutic opportunities and research strategies	60
Tubular TNFSF4/OX40L promotes fibrotic transition following acute kidney injury via activating GSK-3α	60
Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics	60
Phosphoproteomics identifies Rho-kinase-associated phospho-signaling and autophagy-associated alterations in the medial prefrontal cortex of a schizophrenia-related mouse model	59
Functional significance of O-linked N-acetylglucosamine protein modification in regulating autophagy	59
IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics	59
IUPHAR review: The neurobiological outcomes of prenatal opioid exposure: evidence from preclinical models	59
The α9α10 acetylcholine receptor: A non-neuronal nicotinic receptor	58
Game-changer in the fight against Huntington's disease: Cholesterol nanoparticles restore brain function in mice	58
Alternative splicing: A key regulator in T cell response and cancer immunotherapy	58
Therapeutical peptides – Rapidly developing pharmaceutical landscape	58
Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome	58
Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation	57
New therapies towards a better glycemic control in youths with type 1 diabetes	57
The interplay of aging, sleep dysregulation, and mitochondrial dysfunction in metabolic and neurodegenerative diseases	56
Special Issue Spanish Basic and Clinical Pharmacology	55
Editorial Board	55
Treating COVID-19 with NRICM101 and NRICM102 – Author’s reply 3	55
Efficacy and safety of Qingda granule versus valsartan capsule in Chinese grade 1 hypertensive patients with low-moderate risk: A randomized, double-blind, double dummy, non-inferiority, multi-center	55
Leveraging HER2-targeted biparatopic antibodies in solid tumors	54
Post-stroke administration of H2 relaxin reduces functional deficits, neuronal apoptosis and immune cell infiltration into the mouse brain	54
Impaired PARP1-dependent DNA repair in MORC2 mutations drives axonal degeneration in Charcot-Marie-Tooth disease subtype 2Z and spinal muscular atrophy-like neuromotor disorders	54
Nanotheranostics in cancer lymph node metastasis: The long road ahead	54
Dapagliflozin acutely improves kidney function in type 2 diabetes mellitus. The PRECARE study	53
Corrigendum to “Ectopic expression of NKG7 enhances CAR-T function and improves the therapeutic efficacy in liquid and solid tumors” [Pharmacol. Res. 210 (2024) 107506]	53
Corrigendum to “A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME” [Pharmacol. Res. 181 (2022) 106269]	53
Ferroportin 1 depletion in neural stem cells promotes hippocampal neurogenesis and cognitive function in mice	52
Cannabidiol and Beta-Caryophyllene: Chronic inflammatory pain	52
Perturbations of CB1 receptor signalling during adolescence impair cortical myelination in female rats	52
Gut microbiota and well-being: A comprehensive summary of the special issue	52
Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science	52
Systematic druggable genome-wide Mendelian randomization to identify therapeutic targets and dominant flora for ulcerative colitis	51
Corrigendum to “Paclitaxel-Ang-2-functionalized bionic mesoporous selenium nanoparticles for targeted therapy of glioma” [Pharmacol. Res. 216 (2025) 107783]	51
Design of the distribution of iron oxide (Fe3O4) nano-particle drug in realistic cholangiocarcinoma model and the simulation of temperature increase during magnetic induction hyperthermia	51
Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression	51
Neutrophils as potential therapeutic targets for breast cancer	50
KV11.1 (hERG1)-centered macromolecular membrane complexes regulate proliferation in B cell lymphomas and constitute novel pharmacological targets	50
SGK1-inhibition restores cardiac repolarization in LQT2 rabbits and LQT3 mice by reducing late sodium current	50

MicroRNA-based therapeutics for inflammatory disorders of the microbiota-gut-brain axis	50
Adaptive immunity in osteoarthritis: Mechanisms and opportunities for regulatory T-cell–targeted therapy	50
A panel of altered blood oxysterols in patients with mild cognitive impairment: A novel combined diagnostic marker	50
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio	50
The role and potential mechanism of O-Glycosylation in gastrointestinal tumors	50
New therapeutic avenues in multiple sclerosis: Is there a place for gut microbiota-based treatments?	49
Gut microbiota-driven metabolic alterations reveal the distinct pathogenicity of chemotherapy-induced cachexia in gastric cancer	49
Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy	49
Action and therapeutic targets of myosin light chain kinase, an important cardiovascular signaling mechanism	49
Kallistatin leads to cognition impairment via downregulating glutamine synthetase	49
MDA-9/Syntenin small molecule inhibitor IVMT-Rx-4 blocks prostate cancer bone metastasis	49
Lipoxin-mediated signaling: ALX/FPR2 interaction and beyond	49
Regulation of glycolysis-derived L-lactate production in astrocytes rescues the memory deficits and Aβ burden in early Alzheimer’s disease models	49
Mitochondria-targeted hydrogen sulfide donor reduces fatty liver and obesity in mice fed a high fat diet by inhibiting de novo lipogenesis and inflammation via mTOR/SREBP-1 and NF-κB signaling pathway	49
Ketogenic diet in children and adolescents: The effects on growth and nutritional status	49
Role for the F-box proteins in heart diseases	49
ER-organelle contacts: A signaling hub for neurological diseases	49
Understanding the habenula: A major node in circuits regulating emotion and motivation	49
Targeting LRP6: A new strategy for cancer therapy	48
MAO inhibitors for treatment-resistant depression: Bringing an updated perspective on pioneering drugs	48
Protein S-palmitoylation: Dynamic regulatory networks, physiological functions, and new frontiers in targeted therapy	48
Polyol pathway and redox balance in diabetes	48
Breaking through the treatment desert of conventional mesothelin-targeted CAR-T cell therapy for malignant mesothelioma: A glimpse into the future	48
Hv1 channel in immune cells and pharmacology	48
S-glutathionylation in cancer: from fundamental mechanisms to clinical applications	47
Editorial Board	47
Inhibition of long noncoding RNA Gm41724 alleviates pressure overload-induced cardiac fibrosis by regulating lamina-associated polypeptide 2α	47
An ode to valproic acid: A letter to the editor	47
Editorial Board	47
Corrigendum to “Sugiol, a diterpenoid: Therapeutic actions and molecular pathways involved” Pharmacol. Res. 163 (2021) 105313	46
Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen- and prolactin-receptors in breast cancer	46
Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis	46
Clinical trials of orphan drugs in China over the decade 2012–2022: Opportunities and challenges	46
Paracetamol metabolism by endothelial cells – Potential mechanism underlying intravenous paracetamol-induced hypotension	46
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models	46
Corrigendum to “Tagitinin F has anti-inflammatory, anti-nociceptive and anti-matrix metalloproteinase properties: An in silico, in vitro and in vivo study” [Pharmacol. Res. 164 (2021) 105303]	46
Crosstalk of miRNAs with signaling networks in bladder cancer progression: Therapeutic, diagnostic and prognostic functions	45
Gut microbiota-derived metabolite phenylacetylglutamine in cardiovascular and metabolic diseases	45
Placebo design, reporting compliance, and methodological problems in randomized, placebo-controlled trials of Chinese herbal medicine: A cross-sectional study	45
A novel approach to explore metabolic diseases: Neddylation	45
A hepatocellular carcinoma model with and without parenchymal liver damage that integrates technical and pathophysiological advantages for therapy testing	45
Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis	45
The ketogenic diet modulates tumor-associated neutrophil polarization via the AMOT-YAP/TAZ axis to inhibit colorectal cancer progression	45
ALOX5 inhibition protects against dopaminergic neurons undergoing ferroptosis	45
Mtnr1b deletion disrupts placental angiogenesis through the VEGF signaling pathway leading to fetal growth restriction	45
Targeting regulated cell death (RCD) with naturally derived sesquiterpene lactones in cancer therapy	45
Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis: In vitro and in vivo comparative study	45
Stem cells therapy in neurodegenerative and neuroimmune diseases: Current status of treatments and future prospects	45
HMGA2 regulation by miRNAs in cancer: Affecting cancer hallmarks and therapy response	44
Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases	44
Biological activities, Molecular mechanisms, and Clinical application of Naringin in Metabolic syndrome	44
The role of cannabinoid ligands in neurodegenerative diseases: Emerging anti-inflammatory, immunomodulation and disease-modifying perspectives	44
Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis	44
A review of KLF4 and inflammatory disease: Current status and future perspective	44
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes	43
β-amyloid’s neurotoxic mechanisms as defined by in vitro microelectrode arrays: a review	43
Ginsenoside Re binds Drp1 Leu94 across species to restore mitochondrial homeostasis via Atg1/ULK1-dependent fission-mitophagy coupling in age-related degeneration	43
Circulating cytokines and risk of developing hypertension: A systematic review and meta-analysis	43
Powering prescription: Mitochondria as “Living Drugs” – Definition, clinical applications, and industry advancements	43
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction	43
The addicted brain: How processed foods hijack reward pathways	43
Immunometabolic reprogramming of macrophages: Emerging roles in skeletal muscle regeneration and therapeutic perspectives	43
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy	43
Poly (ADP-ribose) polymerase (PARP) inhibitors approved for the treatment of cancer	42
Remote mobilization of gut Tregs exosomes serves as nanoshuttles for targeted cardioprotection against ischemia/reperfusion injury by ginseng polysaccharides	42
Targeting systemic inflammation in metabolic disorders. A therapeutic candidate for the prevention of cardiovascular diseases?	42
Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders	42
Chimeric antigen receptor-T cell therapy-induced cardiotoxicity: Pathophysiological mechanisms and pharmacological intervention strategies	42
The AIM2 inflammasome: A novel biomarker and target in cardiovascular disease	42
AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease	41
Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges	41
SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-19	41
Diabetic retinopathy in the pediatric population: Pathophysiology, screening, current and future treatments	41
D-arabinose acts as antidepressant by activating the ACSS2-PPARγ/TFEB axis and CRTC1 transcription	41
Gut Clostridium sporogenes-derived indole propionic acid suppresses osteoclast formation by activating pregnane X receptor	41
The potential role of mitochondria in the microbiota-gut-brain axis: Implications for brain health	41
Corrigendum to “Modulation of the JAK/ERK/STAT signaling in melanocortin -induced inhibition of local and systemic responses to myocardial ischemia/reperfusion [Pharmacological Research 72 (2013) 1–8]	40
Critical review on anti-obesity effects of phytochemicals through Wnt/β-catenin signaling pathway	40
Corrigendum to “Anlotinib combined with osimertinib reverses acquired osimertinib resistance in NSCLC by targeting the c-MET/MYC/AXL axis” [Pharmacol. Res. 188 (2023) 106668]	40
How spinal GABAergic circuits modulate cerebral processing of postsurgical pain	40
Correspondence “Validation of fermentation techniques for prebiotic impact on gut microbiota”	40
Corrigendum to “GPR37 promotes cancer growth by binding to CDK6 and represents a new theranostic target in lung adenocarcinoma”[Pharmacol. Res. 183 (2022) 106389]	40
Photopharmacological manipulation of amygdala metabotropic glutamate receptor mGlu4 alleviates neuropathic pain	40
Fibroblast growth factor 16: Molecular mechanisms, signalling crosstalk, and emerging roles in cardiac biology and metabolic regulation	39
Novel targets for treating neurodegenerative diseases: The PKM2-STAT3-hnRNPA1 feedback loop	39
Glutamine deprivation confers immunotherapy resistance by inhibiting IFN-γ signaling in cancer cells	39
Methodological innovations in AI-assisted Chinese patent medicine prescribing	39
The effects of conjugated linoleic acid supplementation on liver function enzymes and malondialdehyde in adults: A GRADE-assessed systematic review and dose-response meta-analysis	39
Investigating the intercalation efficacy of sinomenine with diverse DNA fragments to understand its regulatory role in DNA methylation levels	39
ENPP2 inhibitor improves proliferation in AOM/DSS-induced colorectal cancer mice via remodeling the gut barrier function and gut microbiota composition	39
Beyond lectures and practical courses: Teaching pharmacology using imaginative pedagogical tools	38
Cardiomyocytes, cardiac endothelial cells and fibroblasts contribute to anthracycline-induced cardiac injury through RAS-homologous small GTPases RAC1 and CDC42	38
Promoting remyelination in central nervous system diseases: Potentials and prospects of natural products and herbal medicine	38
Ebronucimab in Chinese patients with hypercholesterolemia---A randomized double-blind placebo-controlled phase 3 trial to evaluate the efficacy and safety of ebronucimab	38
Disrupting the physical interaction between serotonin transporter and soluble guanylate cyclase produces a fast-acting antidepressant activity	38