Pharmacological Research

Article	Citations
Impact of Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer’s disease	345
Congenital diaphragmatic hernia increases the sensitivity of pulmonary arteries to nitric oxide	343
Editorial Board	335
Response to letter to the editor: Letter by Chen et al. regarding article, “Assessment of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer's disease: A pop	249
Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer	245
Progress in the development of modulators targeting Frizzleds	228
Corrigendum to ‘Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70′ [Pharmacol. Res. 100 (2015) 341–352]	212
An account on the history of pharmacology in Spain	199
Chromatin factors: Ready to roll as biomarkers in metastatic colorectal cancer?	194
ARID1A is a coactivator of STAT5 that contributes to CD8+ T cell dysfunction and anti-PD-1 resistance in gastric cancer	183
Research progress on the interaction between oxidative stress and platelets: Another avenue for cancer?	178
Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9	177
Discovery, development, and characterization of potent and selective USP11 inhibitors	164
Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales	156
Natural HSP90 inhibitors as a potential therapeutic intervention in treating cancers: A comprehensive review	154
Echinatin inhibits the growth and metastasis of human osteosarcoma cells through Wnt/β-catenin and p38 signaling pathways	146
Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway	141
Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis	141
Drug-induced atrial fibrillation. A narrative review of a forgotten adverse effect	140
Time-dependent proteomics and drug response in expanding cancer cells	135
Paeoniflorin as a potential therapeutic agent for cerebrovascular diseases: A comprehensive review	132
Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression	124
Astaxanthin: A promising therapeutic agent for organ fibrosis	123
Molecular mechanisms underlying hepatoprotective activity of lutein in the context of intestinal failure-associated liver disease	121
Decoding the Metabolic-immune Axis: Neutrophil glycolysis-driven tumor niche remodeling and its therapeutic exploitation	118

Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020	115
Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of JAK2 Via the JAK2-STAT3-PDL1	113
The function and therapeutic potential of transfer RNA-derived small RNAs in cardiovascular diseases: A review	111
DNMT3a-mediated methylation of TCF21/hnRNPA1 aggravates hepatic fibrosis by regulating the NF-κB signaling pathway	110
Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD	108
Corrigendum to “Impaired PARP1-dependent DNA repair in MORC2 mutations drives axonal degeneration in Charcot-Marie-Tooth disease subtype 2Z and spinal muscular atrophy-like neuromotor disorders” [Phar	105
Gut-vascular axis and postbiotics: The need for clear definitions and further research	103
Rapid 64Cu radiolabeling and in vivo evaluation of DSPE–NODAGA liposomes in a murine mammary tumor model	102
The specific deletion of cyclooxygenase-1 in megakaryocytes/platelets reduces intestinal polyposis in Apc mice	102
Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer	102
Combined effects of clonal hematopoiesis of indeterminate potential and P2Y12 inhibitors on outcomes of patients with ST-segment elevation myocardial infarction: A prospective study	101
Molecular mechanisms of pyroptosis in non-alcoholic steatohepatitis and feasible diagnosis and treatment strategies	99
Chronic caffeine consumption prevents obesity-induced cognitive and memory impairments by reducing neuroinflammation and enhancing neuronal activity in the hippocampus	99
Sex differences in the weight response to GLP-1RA in people with type 2 diabetes. A long-term longitudinal real-world study	97
Spatial proteomic profiling reveals conserved prognostic immune microenvironment features across molecular subtypes in small cell lung cancer	94
Fig-derived exosome-like nanoparticles attenuating bone metastasis of breast cancer through establishing an anti-tumor microenvironment	94
NAFLD-associated hepatocellular carcinoma (HCC) – A compelling case for repositioning of existing mTORc1 inhibitors	93
Protective effect and mechanisms of puerarin in metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis of animal studies	93
Organ-targeted biomarkers of sepsis: A systematic review reveals the value of inflammation and lipid metabolic dysregulation	91
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer	91
Simultaneously blocking ANGPTL3 and CD47 prevents the progression of atherosclerosis through regulating lipid metabolism, macrophagic efferocytosis and lipid peroxidation	88
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation	88
The role of exosomes derived from various sources in facilitating the healing of chronic refractory wounds	86
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy	84
IUPHAR Article: Psilocybin induces long-lasting effects via 5-HT2A receptors in mouse models of chronic pain	83
Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death	83
Profiling the impact of anti-human CD20 monoclonal antibodies on lymphocyte B cell subsets and their precursors in the bone marrow and in lymphoid tissues in an immunocompromised mouse engrafted with	83
Blocking ANGPTL3 and CD47 impact on atherosclerosis-correspondence	83
Single-cell RNA sequencing highlights the roles of C1QB and NKG7 in the pancreatic islet immune microenvironment in type 1 diabetes mellitus	83
Efficacy of vitamin D supplementation as an adjunct therapy for improving inflammatory and oxidative stress biomarkers: An umbrella meta-analysis	83
Functional metabolomics revealed the dual-activation of cAMP-AMP axis is a novel therapeutic target of pancreatic cancer	82
Expand available targets for CAR-T therapy to overcome tumor drug resistance based on the "Evolutionary Traps"	82
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression	82
Elevated activity of plasma dipeptidyl peptidase 4 upon stress can be targeted to reverse tumor immunosuppression	81
Revisiting the renin-angiotensin-aldosterone system in the eye: Mechanistic insights and pharmacological targets	80
A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME	79
Multidisciplinary consensus on the diagnosis and management of patients with atypical Hemolytic Uremic Syndrome (complement-mediated TMA): Recommendations from Italian scientific societies, patient as	79
Sirtuin3 attenuates pressure overload-induced pathological myocardial remodeling by inhibiting cardiomyocyte cuproptosis	78
TSPO-mediated mitochondrial retrograde signaling primes the microglial NLRP3 inflammasome	78
Regulation of nicotinic acetylcholine receptors by post-translational modifications	77
Editorial Board	77
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice	77
Pragmatic diagnostic and therapeutic algorithms to optimize new potassium binder use in cardiorenal disease	77
Remote ischemic conditioning attenuates blood-brain barrier disruption after recombinant tissue plasminogen activator treatment via reducing PDGF-CC	76
Pharmacological targeting of HMGB-1 translocation: A potential therapeutic strategy for COVID-19	76
Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges	75
AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy	75
CircRNA in ocular neovascular diseases: Fundamental mechanism and clinical potential	75
Ginsenoside Ro prevents endothelial injury via promoting Epac1/AMPK- mediated mitochondria protection in early diabetic retinopathy	74
Role of hypoxia in cellular senescence	74

Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma	73
The major histocompatibility complex participates in Parkinson’s disease	73
Gut microbiota and their metabolites in stroke: From mechanistic study toward therapeutic perspectives	72
Astrocytic connexin43 in the medial prefrontal cortex regulates depressive- and anxiety-like behaviors via ATP release	71
Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics	71
Atrial fibrillation: Epigenetic aspects and role of sodium-glucose cotransporter 2 inhibitors	71
Targeted and cytotoxic inhibitors used in the treatment of lung cancers	70
Fei-Yan-Qing-Hua decoction inhibits influenza viral replication by enhancing NK cell maturation and activation through the upregulation of JAK/STAT/T-bet signalling axis	70
DNA repair biomarkers to guide usage of combined PARP inhibitors and chemotherapy: A meta-analysis and systematic review	70
Metabolic disorders affecting the liver and heart: Therapeutic efficacy of miRNA-based therapies?	70
Hydrogen sulfide regulates the redox state of soluble guanylate cyclase in CSE-/- mice corpus cavernosum microcirculation	69
Sailing south from regulations to strategies: Macau as a promising gateway for the export of proprietary Chinese medicines to ASEAN countries	69
Crosstalk mechanisms among gut microbiota, novel programmed cell death, and macrophage polarization	68
Beyond the HPA axis: Synaptic circuits of PVNCRH neurons in stress-related psychiatric disorders	68
Role of Angiopoietin-Tie axis in vascular and lymphatic systems and therapeutic interventions	68
Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease	67
Purinosomes and mitochondria: Dynamic interactomes at the crossroads of metabolism, cell structure, and disease	67
Combining choline bitartrate and vitamin B12 ameliorates cognitive impairment in hypertensive elders with cognitive frailty	67
A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine	67
Hormesis: wound healing and fibroblasts	66
TAK1 blockade as a therapy for retinal neovascularization	66
A copper nanocluster-based multifunctional nanoplatform for augmented chemo/chemodynamic/photodynamic combination therapy of breast cancer	64
The action of curcumin against damage resulting from cerebral stroke: A systematic review	64
The complementary and alternative roles of elemene injection in cancer: An umbrella review	64
α1-adrenoceptor ligands inhibit chemokine receptor heteromerization partners of α1B/D-adrenoceptors via interference with heteromer formation	63
Corrigendum to “Deficiency in adiponectin exaggerates cigarette smoking exposure-induced cardiac contractile dysfunction: Role of autophagy” [Pharm. Res. 100 (2015) 175–89]	62
WITHDRAWN: Red blood cell-derived extracellular vesicles deliver NUP85 siRNA to alleviate MASLD through downregulating SLC27A1/PPAR-γ in hepatocyte	62
Pharmacological targeting of G protein-coupled receptor heteromers	62
Corrigendum to ‘Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein’ [Pharmacol. Res. 175 (2022) 105975]	62
Nasal accumulation and metabolism of Δ9-tetrahydrocannabinol following aerosol (‘vaping’) administration in an adolescent rat model	62
Medical treatment of weight loss in children and adolescents with obesity	62
Pharmacological targeting of microglia dynamics in Alzheimer’s disease: Preclinical and clinical evidence	62
Ferritin nanoconjugates guide trastuzumab brain delivery to promote an antitumor response in murine HER2 + breast cancer brain metastasis	61
Hormesis: Wound healing and keratinocytes	61
IUPHAR editorial: Emerging targets for the treatment of pain: Moving towards non-addicting therapeutics and new preclinical directions	60
Editorial Board	60
Commentary on “Apabetalone, a BET protein inhibitor, inhibits kidney damage in diabetes by preventing pyroptosis via modulating the P300/H3K27ac/PLK1 axis”	60
Dapagliflozin acutely improves kidney function in type 2 diabetes mellitus. The PRECARE study	59
New therapeutic avenues in multiple sclerosis: Is there a place for gut microbiota-based treatments?	59
Corrigendum to “A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME” [Pharmacol. Res. 181 (2022) 106269]	58
Action and therapeutic targets of myosin light chain kinase, an important cardiovascular signaling mechanism	58
Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy	58
Therapeutical peptides – Rapidly developing pharmaceutical landscape	57
Corrigendum to “Ectopic expression of NKG7 enhances CAR-T function and improves the therapeutic efficacy in liquid and solid tumors” [Pharmacol. Res. 210 (2024) 107506]	57
Editorial Board	57
Special Issue Spanish Basic and Clinical Pharmacology	56
Treating COVID-19 with NRICM101 and NRICM102 – Author’s reply 3	56
Game-changer in the fight against Huntington's disease: Cholesterol nanoparticles restore brain function in mice	54
Impaired PARP1-dependent DNA repair in MORC2 mutations drives axonal degeneration in Charcot-Marie-Tooth disease subtype 2Z and spinal muscular atrophy-like neuromotor disorders	53
Efficacy and safety of Qingda granule versus valsartan capsule in Chinese grade 1 hypertensive patients with low-moderate risk: A randomized, double-blind, double dummy, non-inferiority, multi-center	53
KV11.1 (hERG1)-centered macromolecular membrane complexes regulate proliferation in B cell lymphomas and constitute novel pharmacological targets	53
ER-organelle contacts: A signaling hub for neurological diseases	53
Cannabidiol and Beta-Caryophyllene: Chronic inflammatory pain	53
Editorial Board	53
The α9α10 acetylcholine receptor: A non-neuronal nicotinic receptor	52
Kallistatin leads to cognition impairment via downregulating glutamine synthetase	51
Neutrophils as potential therapeutic targets for breast cancer	51
Ferroportin 1 depletion in neural stem cells promotes hippocampal neurogenesis and cognitive function in mice	51
Mitochondria-targeted hydrogen sulfide donor reduces fatty liver and obesity in mice fed a high fat diet by inhibiting de novo lipogenesis and inflammation via mTOR/SREBP-1 and NF-κB signaling pathway	51
Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science	50
Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics	50
Adaptive immunity in osteoarthritis: Mechanisms and opportunities for regulatory T-cell–targeted therapy	49
TRP channels in cancer: Therapeutic opportunities and research strategies	49
Hv1 channel in immune cells and pharmacology	49
Design of the distribution of iron oxide (Fe3O4) nano-particle drug in realistic cholangiocarcinoma model and the simulation of temperature increase during magnetic induction hyperthermia	49
The role and potential mechanism of O-Glycosylation in gastrointestinal tumors	49
Post-stroke administration of H2 relaxin reduces functional deficits, neuronal apoptosis and immune cell infiltration into the mouse brain	49
Lipoxin-mediated signaling: ALX/FPR2 interaction and beyond	49
Polyol pathway and redox balance in diabetes	49
MDA-9/Syntenin small molecule inhibitor IVMT-Rx-4 blocks prostate cancer bone metastasis	48
Nanotheranostics in cancer lymph node metastasis: The long road ahead	48
Leveraging HER2-targeted biparatopic antibodies in solid tumors	48
A panel of altered blood oxysterols in patients with mild cognitive impairment: A novel combined diagnostic marker	48
New therapies towards a better glycemic control in youths with type 1 diabetes	48
IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics	48
Protein S-palmitoylation: Dynamic regulatory networks, physiological functions, and new frontiers in targeted therapy	48
Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation	48
The interplay of aging, sleep dysregulation, and mitochondrial dysfunction in metabolic and neurodegenerative diseases	48
Perturbations of CB1 receptor signalling during adolescence impair cortical myelination in female rats	48
Zedoarondiol inhibits atherosclerosis by regulating monocyte migration and adhesion via CXCL12/CXCR4 pathway	48

Ketogenic diet in children and adolescents: The effects on growth and nutritional status	47
SGK1-inhibition restores cardiac repolarization in LQT2 rabbits and LQT3 mice by reducing late sodium current	47
Systematic druggable genome-wide Mendelian randomization to identify therapeutic targets and dominant flora for ulcerative colitis	47
Gut microbiota-driven metabolic alterations reveal the distinct pathogenicity of chemotherapy-induced cachexia in gastric cancer	47
Understanding the habenula: A major node in circuits regulating emotion and motivation	47
Role for the F-box proteins in heart diseases	47
Targeting LRP6: A new strategy for cancer therapy	46
Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome	46
Regulation of glycolysis-derived L-lactate production in astrocytes rescues the memory deficits and Aβ burden in early Alzheimer’s disease models	46
Functional significance of O-linked N-acetylglucosamine protein modification in regulating autophagy	46
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio	46
Gut microbiota and well-being: A comprehensive summary of the special issue	45
MicroRNA-based therapeutics for inflammatory disorders of the microbiota-gut-brain axis	45
Phosphoproteomics identifies Rho-kinase-associated phospho-signaling and autophagy-associated alterations in the medial prefrontal cortex of a schizophrenia-related mouse model	45
Alternative splicing: A key regulator in T cell response and cancer immunotherapy	45
Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression	45
Corrigendum to “Paclitaxel-Ang-2-functionalized bionic mesoporous selenium nanoparticles for targeted therapy of glioma” [Pharmacol. Res. 216 (2025) 107783]	45
Inhibition of long noncoding RNA Gm41724 alleviates pressure overload-induced cardiac fibrosis by regulating lamina-associated polypeptide 2α	44
Breaking through the treatment desert of conventional mesothelin-targeted CAR-T cell therapy for malignant mesothelioma: A glimpse into the future	44
Editorial Board	44
Editorial Board	44
MAO inhibitors for treatment-resistant depression: Bringing an updated perspective on pioneering drugs	44
An ode to valproic acid: A letter to the editor	44
Stem cells therapy in neurodegenerative and neuroimmune diseases: Current status of treatments and future prospects	43
Ginsenoside Re binds Drp1 Leu94 across species to restore mitochondrial homeostasis via Atg1/ULK1-dependent fission-mitophagy coupling in age-related degeneration	43
Corrigendum to “Tagitinin F has anti-inflammatory, anti-nociceptive and anti-matrix metalloproteinase properties: An in silico, in vitro and in vivo study” [Pharmacol. Res. 164 (2021) 105303]	43
S-glutathionylation in cancer: from fundamental mechanisms to clinical applications	43
Paracetamol metabolism by endothelial cells – Potential mechanism underlying intravenous paracetamol-induced hypotension	43
Corrigendum to “Sugiol, a diterpenoid: Therapeutic actions and molecular pathways involved” Pharmacol. Res. 163 (2021) 105313	43
Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis	43
Poly (ADP-ribose) polymerase (PARP) inhibitors approved for the treatment of cancer	43
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy	43
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models	42
Crosstalk of miRNAs with signaling networks in bladder cancer progression: Therapeutic, diagnostic and prognostic functions	42
D-arabinose acts as antidepressant by activating the ACSS2-PPARγ/TFEB axis and CRTC1 transcription	42
Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis	42
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction	42
Powering prescription: Mitochondria as “Living Drugs” – Definition, clinical applications, and industry advancements	42
Targeting regulated cell death (RCD) with naturally derived sesquiterpene lactones in cancer therapy	42
A hepatocellular carcinoma model with and without parenchymal liver damage that integrates technical and pathophysiological advantages for therapy testing	42
Mtnr1b deletion disrupts placental angiogenesis through the VEGF signaling pathway leading to fetal growth restriction	42
HMGA2 regulation by miRNAs in cancer: Affecting cancer hallmarks and therapy response	42
The ketogenic diet modulates tumor-associated neutrophil polarization via the AMOT-YAP/TAZ axis to inhibit colorectal cancer progression	42
Targeting systemic inflammation in metabolic disorders. A therapeutic candidate for the prevention of cardiovascular diseases?	41
Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis	41
SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-19	41
Biological activities, Molecular mechanisms, and Clinical application of Naringin in Metabolic syndrome	41
The AIM2 inflammasome: A novel biomarker and target in cardiovascular disease	41
Diabetic retinopathy in the pediatric population: Pathophysiology, screening, current and future treatments	41
Immunometabolic reprogramming of macrophages: Emerging roles in skeletal muscle regeneration and therapeutic perspectives	40
Clinical trials of orphan drugs in China over the decade 2012–2022: Opportunities and challenges	40
Circulating cytokines and risk of developing hypertension: A systematic review and meta-analysis	40
The role of cannabinoid ligands in neurodegenerative diseases: Emerging anti-inflammatory, immunomodulation and disease-modifying perspectives	40
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes	40
Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen- and prolactin-receptors in breast cancer	40
A novel approach to explore metabolic diseases: Neddylation	40
AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease	39
The addicted brain: How processed foods hijack reward pathways	39
A review of KLF4 and inflammatory disease: Current status and future perspective	39
β-amyloid’s neurotoxic mechanisms as defined by in vitro microelectrode arrays: a review	39
Remote mobilization of gut Tregs exosomes serves as nanoshuttles for targeted cardioprotection against ischemia/reperfusion injury by ginseng polysaccharides	39
Gut Clostridium sporogenes-derived indole propionic acid suppresses osteoclast formation by activating pregnane X receptor	39
Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders	39
Gut microbiota-derived metabolite phenylacetylglutamine in cardiovascular and metabolic diseases	39
The potential role of mitochondria in the microbiota-gut-brain axis: Implications for brain health	39
Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges	39
ALOX5 inhibition protects against dopaminergic neurons undergoing ferroptosis	39
Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis: In vitro and in vivo comparative study	39
Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases	39
Corrigendum to “Modulation of the JAK/ERK/STAT signaling in melanocortin -induced inhibition of local and systemic responses to myocardial ischemia/reperfusion [Pharmacological Research 72 (2013) 1–8]	38
A TRPV1 agonist from the transcriptome profiling of Dipsastraea rotumana inhibits neuroinflammation in vivo through the NF-κB and MAPK pathways	38
Improving glioma drug delivery: A multifaceted approach for glioma drug development	38
Corrigendum to “Anlotinib combined with osimertinib reverses acquired osimertinib resistance in NSCLC by targeting the c-MET/MYC/AXL axis” [Pharmacol. Res. 188 (2023) 106668]	38
The effects of conjugated linoleic acid supplementation on liver function enzymes and malondialdehyde in adults: A GRADE-assessed systematic review and dose-response meta-analysis	38
Single-cell RNA-sequencing data reveals the genetic source of extracellular vesicles in esophageal squamous cell carcinoma	38
Correspondence “Validation of fermentation techniques for prebiotic impact on gut microbiota”	38
Corrigendum to “GPR37 promotes cancer growth by binding to CDK6 and represents a new theranostic target in lung adenocarcinoma”[Pharmacol. Res. 183 (2022) 106389]	38
The REEP family of proteins: Molecular targets and role in pathophysiology	38
Photopharmacological manipulation of amygdala metabotropic glutamate receptor mGlu4 alleviates neuropathic pain	38
Fibroblast growth factor 16: Molecular mechanisms, signalling crosstalk, and emerging roles in cardiac biology and metabolic regulation	37
A comprehensive review of the multifaceted role of cannabinoid receptor type 2 in neurodegenerative and neuropsychiatric disorders	37
Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma	37
Ginsenoside Rh2 augmented anti-PD-L1 immunotherapy by reinvigorating CD8+ T cells via increasing intratumoral CXCL10	37
Efficacy of erythropoietin as a neuroprotective agent in CKD-associated cognitive dysfunction: A literature systematic review	37
Novel targets for treating neurodegenerative diseases: The PKM2-STAT3-hnRNPA1 feedback loop	37
Methodological innovations in AI-assisted Chinese patent medicine prescribing	37
Ginkgolide B targets and inhibits creatine kinase B to regulate the CCT/TRiC-SK1 axis and exerts pro-angiogenic activity in middle cerebral artery occlusion mice	37
Investigating the intercalation efficacy of sinomenine with diverse DNA fragments to understand its regulatory role in DNA methylation levels	37
Promoting remyelination in central nervous system diseases: Potentials and prospects of natural products and herbal medicine	36
Modulation of the nitric oxide/cGMP pathway in cardiac contraction and relaxation: Potential role in heart failure treatment	36
Optical imaging guidance in oncologic surgery and interventional oncology	36
Targeted gut microbiome therapy: Applications and prospects of probiotics, fecal microbiota transplantation and natural products in the management of type 2 diabetes	36
ephrin-B2 promotes nociceptive plasticity and hyperalgesic priming through EphB2-MNK-eIF4E signaling in both mice and humans	36
Targeting EVA1B in breast cancer: New avenues for precision oncology	36
Critical review on anti-obesity effects of phytochemicals through Wnt/β-catenin signaling pathway	36