Pharmacological Research

Papers
(The median citation count of Pharmacological Research is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Impact of Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer’s disease337
G-protein biased signaling agonists of Dopamine D3 receptor promote distinct activation patterns of ERK1/2334
Congenital diaphragmatic hernia increases the sensitivity of pulmonary arteries to nitric oxide318
Decoding the Metabolic-immune Axis: Neutrophil glycolysis-driven tumor niche remodeling and its therapeutic exploitation249
Editorial Board238
Response to letter to the editor: Letter by Chen et al. regarding article, “Assessment of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and other antidiabetic agents in Alzheimer's disease: A pop218
Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression195
Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis189
Paeoniflorin as a potential therapeutic agent for cerebrovascular diseases: A comprehensive review187
Combination of palbociclib with navitoclax based-therapies enhances in vivo antitumoral activity in triple-negative breast cancer179
Spatial proteomic profiling reveals conserved prognostic immune microenvironment features across molecular subtypes in small cell lung cancer174
Organ-targeted biomarkers of sepsis: A systematic review reveals the value of inflammation and lipid metabolic dysregulation171
Progress in the development of modulators targeting Frizzleds161
Corrigendum to ‘Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70′ [Pharmacol. Res. 100 (2015) 341–352]153
An account on the history of pharmacology in Spain150
Chromatin factors: Ready to roll as biomarkers in metastatic colorectal cancer?143
ARID1A is a coactivator of STAT5 that contributes to CD8+ T cell dysfunction and anti-PD-1 resistance in gastric cancer137
Time-dependent proteomics and drug response in expanding cancer cells137
Protective effect and mechanisms of puerarin in metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis of animal studies134
Research progress on the interaction between oxidative stress and platelets: Another avenue for cancer?132
DNMT3a-mediated methylation of TCF21/hnRNPA1 aggravates hepatic fibrosis by regulating the NF-κB signaling pathway129
Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9126
Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales122
Discovery, development, and characterization of potent and selective USP11 inhibitors122
Simultaneously blocking ANGPTL3 and CD47 prevents the progression of atherosclerosis through regulating lipid metabolism, macrophagic efferocytosis and lipid peroxidation118
Combined effects of clonal hematopoiesis of indeterminate potential and P2Y12 inhibitors on outcomes of patients with ST-segment elevation myocardial infarction: A prospective study116
Drug-induced atrial fibrillation. A narrative review of a forgotten adverse effect113
NAFLD-associated hepatocellular carcinoma (HCC) – A compelling case for repositioning of existing mTORc1 inhibitors105
Natural HSP90 inhibitors as a potential therapeutic intervention in treating cancers: A comprehensive review105
Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020105
Echinatin inhibits the growth and metastasis of human osteosarcoma cells through Wnt/β-catenin and p38 signaling pathways104
Therapeutic implications of sonic hedgehog pathway in metabolic disorders: Novel target for effective treatment102
Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death101
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation100
Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer99
The function and therapeutic potential of transfer RNA-derived small RNAs in cardiovascular diseases: A review98
Astaxanthin: A promising therapeutic agent for organ fibrosis97
Rapid 64Cu radiolabeling and in vivo evaluation of DSPE–NODAGA liposomes in a murine mammary tumor model96
Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of JAK2 Via the JAK2-STAT3-PDL192
Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway92
Molecular mechanisms underlying hepatoprotective activity of lutein in the context of intestinal failure-associated liver disease91
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer91
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy91
Chronic caffeine consumption prevents obesity-induced cognitive and memory impairments by reducing neuroinflammation and enhancing neuronal activity in the hippocampus90
Corrigendum to “Impaired PARP1-dependent DNA repair in MORC2 mutations drives axonal degeneration in Charcot-Marie-Tooth disease subtype 2Z and spinal muscular atrophy-like neuromotor disorders” [Phar88
Sex differences in the weight response to GLP-1RA in people with type 2 diabetes. A long-term longitudinal real-world study88
The specific deletion of cyclooxygenase-1 in megakaryocytes/platelets reduces intestinal polyposis in Apc mice86
Fig-derived exosome-like nanoparticles attenuating bone metastasis of breast cancer through establishing an anti-tumor microenvironment86
Phloretin ameliorates diabetes-induced endothelial injury through AMPK-dependent anti-EndMT pathway84
Molecular mechanisms of pyroptosis in non-alcoholic steatohepatitis and feasible diagnosis and treatment strategies83
Telmisartan reverses hepatic steatosis via PCK1 upregulation: A novel PPAR-independent mechanism in experimental models of MASLD83
Gut-vascular axis and postbiotics: The need for clear definitions and further research83
The role of exosomes derived from various sources in facilitating the healing of chronic refractory wounds82
Efficacy of vitamin D supplementation as an adjunct therapy for improving inflammatory and oxidative stress biomarkers: An umbrella meta-analysis82
Sailing south from regulations to strategies: Macau as a promising gateway for the export of proprietary Chinese medicines to ASEAN countries81
Blocking ANGPTL3 and CD47 impact on atherosclerosis-correspondence81
IUPHAR Article: Psilocybin induces long-lasting effects via 5-HT2A receptors in mouse models of chronic pain79
Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges79
Single-cell RNA sequencing highlights the roles of C1QB and NKG7 in the pancreatic islet immune microenvironment in type 1 diabetes mellitus78
Metabolic disorders affecting the liver and heart: Therapeutic efficacy of miRNA-based therapies?78
Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma77
Profiling the impact of anti-human CD20 monoclonal antibodies on lymphocyte B cell subsets and their precursors in the bone marrow and in lymphoid tissues in an immunocompromised mouse engrafted with 76
Expand available targets for CAR-T therapy to overcome tumor drug resistance based on the "Evolutionary Traps"76
Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models75
Functional metabolomics revealed the dual-activation of cAMP-AMP axis is a novel therapeutic target of pancreatic cancer75
The major histocompatibility complex participates in Parkinson’s disease75
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression75
Elevated activity of plasma dipeptidyl peptidase 4 upon stress can be targeted to reverse tumor immunosuppression75
Editorial Board74
Regulation of nicotinic acetylcholine receptors by post-translational modifications74
DNA repair biomarkers to guide usage of combined PARP inhibitors and chemotherapy: A meta-analysis and systematic review73
Pragmatic diagnostic and therapeutic algorithms to optimize new potassium binder use in cardiorenal disease73
Pharmacological targeting of HMGB-1 translocation: A potential therapeutic strategy for COVID-1973
α1-adrenoceptor ligands inhibit chemokine receptor heteromerization partners of α1B/D-adrenoceptors via interference with heteromer formation72
The complementary and alternative roles of elemene injection in cancer: An umbrella review72
Corrigendum to “Deficiency in adiponectin exaggerates cigarette smoking exposure-induced cardiac contractile dysfunction: Role of autophagy” [Pharm. Res. 100 (2015) 175–89]72
Corrigendum to ‘Glabratephrin reverses doxorubicin resistance in triple negative breast cancer by inhibiting P-glycoprotein’ [Pharmacol. Res. 175 (2022) 105975]71
Pharmacological targeting of G protein-coupled receptor heteromers70
Medical treatment of weight loss in children and adolescents with obesity70
Nasal accumulation and metabolism of Δ9-tetrahydrocannabinol following aerosol (‘vaping’) administration in an adolescent rat model70
WITHDRAWN: Red blood cell-derived extracellular vesicles deliver NUP85 siRNA to alleviate MASLD through downregulating SLC27A1/PPAR-γ in hepatocyte70
Crosstalk mechanisms among gut microbiota, novel programmed cell death, and macrophage polarization69
TSPO-mediated mitochondrial retrograde signaling primes the microglial NLRP3 inflammasome69
Combining choline bitartrate and vitamin B12 ameliorates cognitive impairment in hypertensive elders with cognitive frailty68
Purinosomes and mitochondria: Dynamic interactomes at the crossroads of metabolism, cell structure, and disease68
A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine67
Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease67
Recent advances in glioma microenvironment-response nanoplatforms for phototherapy and sonotherapy67
Multidisciplinary consensus on the diagnosis and management of patients with atypical Hemolytic Uremic Syndrome (complement-mediated TMA): Recommendations from Italian scientific societies, patient as67
Hormesis: wound healing and fibroblasts66
Role of Angiopoietin-Tie axis in vascular and lymphatic systems and therapeutic interventions66
TAK1 blockade as a therapy for retinal neovascularization65
CircRNA in ocular neovascular diseases: Fundamental mechanism and clinical potential64
A copper nanocluster-based multifunctional nanoplatform for augmented chemo/chemodynamic/photodynamic combination therapy of breast cancer64
The action of curcumin against damage resulting from cerebral stroke: A systematic review64
Ginsenoside Ro prevents endothelial injury via promoting Epac1/AMPK- mediated mitochondria protection in early diabetic retinopathy63
Hormesis: Wound healing and keratinocytes63
Revisiting the renin-angiotensin-aldosterone system in the eye: Mechanistic insights and pharmacological targets62
Hydrogen sulfide regulates the redox state of soluble guanylate cyclase in CSE-/- mice corpus cavernosum microcirculation62
Ferritin nanoconjugates guide trastuzumab brain delivery to promote an antitumor response in murine HER2 + breast cancer brain metastasis62
Beyond the HPA axis: Synaptic circuits of PVNCRH neurons in stress-related psychiatric disorders61
Gut microbiota and their metabolites in stroke: From mechanistic study toward therapeutic perspectives61
Remote ischemic conditioning attenuates blood-brain barrier disruption after recombinant tissue plasminogen activator treatment via reducing PDGF-CC61
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice61
AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy61
Targeted and cytotoxic inhibitors used in the treatment of lung cancers60
Fei-Yan-Qing-Hua decoction inhibits influenza viral replication by enhancing NK cell maturation and activation through the upregulation of JAK/STAT/T-bet signalling axis60
Sirtuin3 attenuates pressure overload-induced pathological myocardial remodeling by inhibiting cardiomyocyte cuproptosis60
Role of hypoxia in cellular senescence60
IUPHAR editorial: Emerging targets for the treatment of pain: Moving towards non-addicting therapeutics and new preclinical directions59
A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME59
Atrial fibrillation: Epigenetic aspects and role of sodium-glucose cotransporter 2 inhibitors59
Pharmacological targeting of microglia dynamics in Alzheimer’s disease: Preclinical and clinical evidence59
Commentary on “Apabetalone, a BET protein inhibitor, inhibits kidney damage in diabetes by preventing pyroptosis via modulating the P300/H3K27ac/PLK1 axis”59
Astrocytic connexin43 in the medial prefrontal cortex regulates depressive- and anxiety-like behaviors via ATP release59
Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics59
Editorial Board58
Therapeutical peptides – Rapidly developing pharmaceutical landscape58
Design of the distribution of iron oxide (Fe3O4) nano-particle drug in realistic cholangiocarcinoma model and the simulation of temperature increase during magnetic induction hyperthermia58
Gut microbiota and well-being: A comprehensive summary of the special issue58
Targeting LRP6: A new strategy for cancer therapy57
TRP channels in cancer: Therapeutic opportunities and research strategies57
Game-changer in the fight against Huntington's disease: Cholesterol nanoparticles restore brain function in mice56
Efficacy and safety of Qingda granule versus valsartan capsule in Chinese grade 1 hypertensive patients with low-moderate risk: A randomized, double-blind, double dummy, non-inferiority, multi-center 56
Editorial Board54
Editorial Board53
Treating COVID-19 with NRICM101 and NRICM102 – Author’s reply 353
Special Issue Spanish Basic and Clinical Pharmacology53
Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming52
ER-organelle contacts: A signaling hub for neurological diseases52
Dapagliflozin acutely improves kidney function in type 2 diabetes mellitus. The PRECARE study51
Corrigendum to “Ectopic expression of NKG7 enhances CAR-T function and improves the therapeutic efficacy in liquid and solid tumors” [Pharmacol. Res. 210 (2024) 107506]50
New therapies towards a better glycemic control in youths with type 1 diabetes50
Corrigendum to “A novel immune checkpoint siglec-15 antibody inhibits LUAD by modulating mφ polarization in TME” [Pharmacol. Res. 181 (2022) 106269]50
Corrigendum to “Paclitaxel-Ang-2-functionalized bionic mesoporous selenium nanoparticles for targeted therapy of glioma” [Pharmacol. Res. 216 (2025) 107783]50
Impaired PARP1-dependent DNA repair in MORC2 mutations drives axonal degeneration in Charcot-Marie-Tooth disease subtype 2Z and spinal muscular atrophy-like neuromotor disorders49
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio49
Leveraging HER2-targeted biparatopic antibodies in solid tumors49
Nanotheranostics in cancer lymph node metastasis: The long road ahead49
MicroRNA-based therapeutics for inflammatory disorders of the microbiota-gut-brain axis49
Systematic druggable genome-wide Mendelian randomization to identify therapeutic targets and dominant flora for ulcerative colitis49
KV11.1 (hERG1)-centered macromolecular membrane complexes regulate proliferation in B cell lymphomas and constitute novel pharmacological targets48
Hv1 channel in immune cells and pharmacology48
Cannabidiol and Beta-Caryophyllene: Chronic inflammatory pain48
Post-stroke administration of H2 relaxin reduces functional deficits, neuronal apoptosis and immune cell infiltration into the mouse brain48
Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression48
Role for the F-box proteins in heart diseases47
Mitochondria-targeted hydrogen sulfide donor reduces fatty liver and obesity in mice fed a high fat diet by inhibiting de novo lipogenesis and inflammation via mTOR/SREBP-1 and NF-κB signaling pathway47
New therapeutic avenues in multiple sclerosis: Is there a place for gut microbiota-based treatments?47
Ferroportin 1 depletion in neural stem cells promotes hippocampal neurogenesis and cognitive function in mice47
Neutrophils as potential therapeutic targets for breast cancer47
Potential of diterpenes as antidiabetic agents: Evidence from clinical and pre-clinical studies47
A panel of altered blood oxysterols in patients with mild cognitive impairment: A novel combined diagnostic marker47
The α9α10 acetylcholine receptor: A non-neuronal nicotinic receptor47
Perturbations of CB1 receptor signalling during adolescence impair cortical myelination in female rats47
Adaptive immunity in osteoarthritis: Mechanisms and opportunities for regulatory T-cell–targeted therapy47
Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy47
Zedoarondiol inhibits atherosclerosis by regulating monocyte migration and adhesion via CXCL12/CXCR4 pathway46
Gut microbiota-driven metabolic alterations reveal the distinct pathogenicity of chemotherapy-induced cachexia in gastric cancer46
Lipoxin-mediated signaling: ALX/FPR2 interaction and beyond46
Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science46
Kallistatin leads to cognition impairment via downregulating glutamine synthetase46
Action and therapeutic targets of myosin light chain kinase, an important cardiovascular signaling mechanism45
IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics44
MDA-9/Syntenin small molecule inhibitor IVMT-Rx-4 blocks prostate cancer bone metastasis44
Alternative splicing: A key regulator in T cell response and cancer immunotherapy44
Protein S-palmitoylation: Dynamic regulatory networks, physiological functions, and new frontiers in targeted therapy44
Phosphoproteomics identifies Rho-Kinase-associated phospho-signaling and autophagy-associated alterations in the medial prefrontal cortex of a schizophrenia-related mouse model44
Functional significance of O-linked N-acetylglucosamine protein modification in regulating autophagy44
Polyol pathway and redox balance in diabetes44
SGK1-inhibition restores cardiac repolarization in LQT2 rabbits and LQT3 mice by reducing late sodium current44
Regulation of glycolysis-derived L-lactate production in astrocytes rescues the memory deficits and Aβ burden in early Alzheimer’s disease models43
The role and potential mechanism of O-Glycosylation in gastrointestinal tumors43
Understanding the habenula: A major node in circuits regulating emotion and motivation43
Breaking through the treatment desert of conventional mesothelin-targeted CAR-T cell therapy for malignant mesothelioma: A glimpse into the future43
Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome43
MAO inhibitors for treatment-resistant depression: Bringing an updated perspective on pioneering drugs43
Ketogenic diet in children and adolescents: The effects on growth and nutritional status43
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models43
Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics43
Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation43
The interplay of aging, sleep dysregulation, and mitochondrial dysfunction in metabolic and neurodegenerative diseases43
Ginsenoside Re binds Drp1 Leu94 across species to restore mitochondrial homeostasis via Atg1/ULK1-dependent fission-mitophagy coupling in age-related degeneration42
Editorial Board42
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes42
Clinical trials of orphan drugs in China over the decade 2012–2022: Opportunities and challenges42
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy42
An ode to valproic acid: A letter to the editor42
Corrigendum to “Sugiol, a diterpenoid: Therapeutic actions and molecular pathways involved” Pharmacol. Res. 163 (2021) 10531342
Mtnr1b deletion disrupts placental angiogenesis through the VEGF signaling pathway leading to fetal growth restriction42
Paracetamol metabolism by endothelial cells – Potential mechanism underlying intravenous paracetamol-induced hypotension42
D-arabinose acts as antidepressant by activating the ACSS2-PPARγ/TFEB axis and CRTC1 transcription42
Inhibition of long noncoding RNA Gm41724 alleviates pressure overload-induced cardiac fibrosis by regulating lamina-associated polypeptide 2α42
Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen- and prolactin-receptors in breast cancer41
Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis41
Circulating cytokines and risk of developing hypertension: A systematic review and meta-analysis41
Editorial Board41
β-amyloid’s neurotoxic mechanisms as defined by in vitro microelectrode arrays: a review41
Corrigendum to “Tagitinin F has anti-inflammatory, anti-nociceptive and anti-matrix metalloproteinase properties: An in silico, in vitro and in vivo study” [Pharmacol. Res. 164 (2021) 105303]41
Gut microbiota-derived metabolite phenylacetylglutamine in cardiovascular and metabolic diseases41
Diabetic retinopathy in the pediatric population: Pathophysiology, screening, current and future treatments41
Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders40
A novel approach to explore metabolic diseases: Neddylation40
Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction40
Immunometabolic reprogramming of macrophages: Emerging roles in skeletal muscle regeneration and therapeutic perspectives40
Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis40
Gut Clostridium sporogenes-derived indole propionic acid suppresses osteoclast formation by activating pregnane X receptor40
Stem cells therapy in neurodegenerative and neuroimmune diseases: Current status of treatments and future prospects40
Poly (ADP-ribose) polymerase (PARP) inhibitors approved for the treatment of cancer39
Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis: In vitro and in vivo comparative study39
Targeting regulated cell death (RCD) with naturally derived sesquiterpene lactones in cancer therapy39
A review of KLF4 and inflammatory disease: Current status and future perspective39
S-glutathionylation in cancer: from fundamental mechanisms to clinical applications39
A hepatocellular carcinoma model with and without parenchymal liver damage that integrates technical and pathophysiological advantages for therapy testing39
ALOX5 inhibition protects against dopaminergic neurons undergoing ferroptosis39
HMGA2 regulation by miRNAs in cancer: Affecting cancer hallmarks and therapy response39
The ketogenic diet modulates tumor-associated neutrophil polarization via the AMOT-YAP/TAZ axis to inhibit colorectal cancer progression39
The AIM2 inflammasome: A novel biomarker and target in cardiovascular disease39
Powering prescription: Mitochondria as “Living Drugs” – Definition, clinical applications, and industry advancements39
Targeting systemic inflammation in metabolic disorders. A therapeutic candidate for the prevention of cardiovascular diseases?38
Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis38
Crosstalk of miRNAs with signaling networks in bladder cancer progression: Therapeutic, diagnostic and prognostic functions38
AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease38
The addicted brain: How processed foods hijack reward pathways38
SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-1938
Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases38
Biological activities, Molecular mechanisms, and Clinical application of Naringin in Metabolic syndrome38
The role of cannabinoid ligands in neurodegenerative diseases: Emerging anti-inflammatory, immunomodulation and disease-modifying perspectives38
Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges38
Corrigendum to “Modulation of the JAK/ERK/STAT signaling in melanocortin -induced inhibition of local and systemic responses to myocardial ischemia/reperfusion [Pharmacological Research 72 (2013) 1–8]37
Corrigendum to “Anlotinib combined with osimertinib reverses acquired osimertinib resistance in NSCLC by targeting the c-MET/MYC/AXL axis” [Pharmacol. Res. 188 (2023) 106668]37
Ebronucimab in Chinese patients with hypercholesterolemia---A randomized double-blind placebo-controlled phase 3 trial to evaluate the efficacy and safety of ebronucimab37
Correspondence “Validation of fermentation techniques for prebiotic impact on gut microbiota”37
Targeting EVA1B in breast cancer: New avenues for precision oncology37
Copper metabolism and its role in diabetic complications: A review37
The potential role of mitochondria in the microbiota-gut-brain axis: Implications for brain health37
Investigating the intercalation efficacy of sinomenine with diverse DNA fragments to understand its regulatory role in DNA methylation levels37
Corrigendum to “GPR37 promotes cancer growth by binding to CDK6 and represents a new theranostic target in lung adenocarcinoma”[Pharmacol. Res. 183 (2022) 106389]37
Cardiomyocytes, cardiac endothelial cells and fibroblasts contribute to anthracycline-induced cardiac injury through RAS-homologous small GTPases RAC1 and CDC4236
Improving glioma drug delivery: A multifaceted approach for glioma drug development36
Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma36
Methodological innovations in AI-assisted Chinese patent medicine prescribing36
Novel targets for treating neurodegenerative diseases: The PKM2-STAT3-hnRNPA1 feedback loop36
Photopharmacological manipulation of amygdala metabotropic glutamate receptor mGlu4 alleviates neuropathic pain36
ENPP2 inhibitor improves proliferation in AOM/DSS-induced colorectal cancer mice via remodeling the gut barrier function and gut microbiota composition36
Histone lysine crotonylation accelerates ACSL4-mediated ferroptosis of keratinocytes via modulating autophagy in diabetic wound healing36
Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease36
Fibroblast growth factor 16: Molecular mechanisms, signalling crosstalk, and emerging roles in cardiac biology and metabolic regulation36
A TRPV1 agonist from the transcriptome profiling of Dipsastraea rotumana inhibits neuroinflammation in vivo through the NF-κB and MAPK pathways36
Targeted gut microbiome therapy: Applications and prospects of probiotics, fecal microbiota transplantation and natural products in the management of type 2 diabetes35
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