Pharmacological Research

Article	Citations
The role of short-chain fatty acids in intestinal barrier function, inflammation, oxidative stress, and colonic carcinogenesis	328
The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders	323
Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance	280
Properties of FDA-approved small molecule protein kinase inhibitors: A 2021 update	257
Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms	206
Chemical constituents of Panax ginseng and Panax notoginseng explain why they differ in therapeutic efficacy	194
Hydrogen sulfide: An endogenous regulator of the immune system	172
The impact of the microbiota-gut-brain axis on Alzheimer’s disease pathophysiology	172
Ferroptosis and its emerging roles in cardiovascular diseases	157
Properties of FDA-approved small molecule protein kinase inhibitors: A 2022 update	156
Efficacy of Huoxiang Zhengqi dropping pills and Lianhua Qingwen granules in treatment of COVID-19: A randomized controlled trial	153
Properties of FDA-approved small molecule protein kinase inhibitors: A 2023 update	151
Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells	145
Necrostatin-1 and necroptosis inhibition: Pathophysiology and therapeutic implications	145
Cucurbitacin B inhibits non-small cell lung cancer in vivo and in vitro by triggering TLR4/NLRP3/GSDMD-dependent pyroptosis	144
New progress in the pharmacology of protocatechuic acid: A compound ingested in daily foods and herbs frequently and heavily	143
Skeletal muscle atrophy: From mechanisms to treatments	138
HDAC6 as privileged target in drug discovery: A perspective	132
Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis	131
Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative review	131
The hormetic dose-response mechanism: Nrf2 activation	126
Nuclear receptor coactivator 4-mediated ferritinophagy contributes to cerebral ischemia-induced ferroptosis in ischemic stroke	125
“Therapeutic uses of natural astaxanthin: An evidence-based review focused on human clinical trials”	120
Main active components of Jiawei Gegen Qinlian decoction protects against ulcerative colitis under different dietary environments in a gut microbiota-dependent manner	120
RNA methylation and cancer treatment	117

Lactobacillus acidophilus ameliorates obesity in mice through modulation of gut microbiota dysbiosis and intestinal permeability	113
Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects	110
Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites	110
Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer	110
Prospective therapeutic potential of Tanshinone IIA: An updated overview	106
Resveratrol and endothelial function: A literature review	104
Dioscin ameliorates murine ulcerative colitis by regulating macrophage polarization	103
Regulation of blood-retinal barrier cell-junctions in diabetic retinopathy	102
The anti-inflammatory and immunological properties of GLP-1 Receptor Agonists	100
Natural volatile oils derived from herbal medicines: A promising therapy way for treating depressive disorder	99
Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis	98
Dihydromyricetin improves DSS-induced colitis in mice via modulation of fecal-bacteria-related bile acid metabolism	98
Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance	94
Lupeol and its derivatives as anticancer and anti-inflammatory agents: Molecular mechanisms and therapeutic efficacy	94
Perspective on the application of medicinal plants and natural products in wound healing: A mechanistic review	94
Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications	93
Metabolic reprogramming by traditional Chinese medicine and its role in effective cancer therapy	92
Long noncoding RNA p21 enhances autophagy to alleviate endothelial progenitor cells damage and promote endothelial repair in hypertension through SESN2/AMPK/TSC2 pathway	92
The Nrf2 in the pathophysiology of the intestine: Molecular mechanisms and therapeutic implications for inflammatory bowel diseases	90
Chloroquine and hydroxychloroquine in antitumor therapies based on autophagy-related mechanisms	90
Naringenin is a powerful inhibitor of SARS-CoV-2 infection in vitro	90
Current Policies and Measures on the Development of Traditional Chinese Medicine in China	87
Anti-diabetic drugs and weight loss in patients with type 2 diabetes	87
EGFR mutation mediates resistance to EGFR tyrosine kinase inhibitors in NSCLC: From molecular mechanisms to clinical research	86
Urolithin A suppresses RANKL-induced osteoclastogenesis and postmenopausal osteoporosis by, suppresses inflammation and downstream NF-κB activated pyroptosis pathways	85
Baicalin mediated regulation of key signaling pathways in cancer	84
The current use and evolving landscape of nutraceuticals	84
Tumor-associated macrophages: A promising target for a cancer immunotherapeutic strategy	83
Apoptosis, autophagy and atherosclerosis: Relationships and the role of Hsp27	80
Epigenetics in NAFLD/NASH: Targets and therapy	80
Endoplasmic reticulum stress in doxorubicin-induced cardiotoxicity may be therapeutically targeted by natural and chemical compounds: A review	79
Reproductive toxic potential of phthalate compounds – State of art review	77
MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis	76
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy	74
Sesquiterpenes and their derivatives-natural anticancer compounds: An update	73
Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach	72
STAT3-EMT axis in tumors: Modulation of cancer metastasis, stemness and therapy response	72
Acute kidney injury is associated with severe infection and fatality in patients with COVID-19: A systematic review and meta-analysis of 40 studies and 24,527 patients	72
BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection	69
Endoplasmic reticulum stress and protein degradation in chronic liver disease	69
Elucidation of the anti-inflammatory mechanism of Er Miao San by integrative approach of network pharmacology and experimental verification	68
Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway	68
Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases	68
Exosomal ncRNAs: Novel therapeutic target and biomarker for diabetic complications	67
Parthanatos and its associated components: Promising therapeutic targets for cancer	67
Cognitive impairment and type 2 diabetes mellitus: Focus of SGLT2 inhibitors treatment	66
Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature	66
Mitochondria as an important target of metformin: The mechanism of action, toxic and side effects, and new therapeutic applications	66
The novel mechanisms and applications of exosomes in dermatology and cutaneous medical aesthetics	65
The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis	65

Association between early treatment with Qingfei Paidu decoction and favorable clinical outcomes in patients with COVID-19: A retrospective multicenter cohort study	65
The antihypertensive potential of flavonoids from Chinese Herbal Medicine: A review	64
A renewed concept on the MAPK signaling pathway in cancers: Polyphenols as a choice of therapeutics	64
Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway	64
Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry	63
Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: Implications for neurodegenerative disease treatment	63
Polypharmacology: The science of multi-targeting molecules	62
Optimal use of lipid-lowering therapy after acute coronary syndromes: A Position Paper endorsed by the International Lipid Expert Panel (ILEP)	62
Tanshinone IIA: A phytochemical as a promising drug candidate for neurodegenerative diseases	61
Mulberry leaf (Morus alba L.): A review of its potential influences in mechanisms of action on metabolic diseases	61
Ivermectin, a potential anticancer drug derived from an antiparasitic drug	61
Chlorogenic acid for cancer prevention and therapy: Current status on efficacy and mechanisms of action	60
Gut microbiota induces DNA methylation via SCFAs predisposing obesity-prone individuals to diabetes	59
Purinergic signaling orchestrating neuron-glia communication	59
Celastrol in metabolic diseases: Progress and application prospects	59
Thioredoxin reductase as a pharmacological target	59
Garlic constituents for cancer prevention and therapy: From phytochemistry to novel formulations	58
Repurposing of antipsychotic trifluoperazine for treating brain metastasis, lung metastasis and bone metastasis of melanoma by disrupting autophagy flux	58
Cell death regulation: A new way for natural products to treat osteoporosis	58
Outcomes in diabetic patients treated with SGLT2-Inhibitors with acute myocardial infarction undergoing PCI: The SGLT2-I AMI PROTECT Registry	57
Natural and synthetic compounds in Ovarian Cancer: A focus on NRF2/KEAP1 pathway	57
Cholesterol homeostasis: Researching a dialogue between the brain and peripheral tissues	56
Hypoxia-inducible factor-1: Regulatory mechanisms and drug development in stroke	56
Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges	56
Novel selective hexokinase 2 inhibitor Benitrobenrazide blocks cancer cells growth by targeting glycolysis	56
A review of pharmacological and pharmacokinetic properties of Forsythiaside A	56
Resveratrol: Mechanistic and therapeutic perspectives in pulmonary arterial hypertension	55
DNA methylation of FTO promotes renal inflammation by enhancing m6A of PPAR-α in alcohol-induced kidney injury	54
The revitalization of antimicrobial peptides in the resistance era	54
The receptor hypothesis and the pathogenesis of depression: Genetic bases and biological correlates	54
USF2 knockdown downregulates THBS1 to inhibit the TGF-β signaling pathway and reduce pyroptosis in sepsis-induced acute kidney injury	54
Losartan attenuates sepsis-induced cardiomyopathy by regulating macrophage polarization via TLR4-mediated NF-κB and MAPK signaling	54
Naturally-derived targeted therapy for wound healing: Beyond classical strategies	54
Cannabis and its constituents for cancer: History, biogenesis, chemistry and pharmacological activities	53
Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9-tetrahydrocannabinol-exposed rats	53
Effect of melatonin supplementation on oxidative stress parameters: A systematic review and meta-analysis	53
Flubendazole, FDA-approved anthelmintic, elicits valid antitumor effects by targeting P53 and promoting ferroptosis in castration-resistant prostate cancer	53
Pathway network of pyroptosis and its potential inhibitors in acute kidney injury	53
Combining L-Arginine with vitamin C improves long-COVID symptoms: The LINCOLN Survey	53
Role of epigenetic regulation in myocardial ischemia/reperfusion injury	53
Anticancer potential of allicin: A review	53
SIRT1-FOXOs activity regulates diabetic complications	53
Borneol in cardio-cerebrovascular diseases: Pharmacological actions, mechanisms, and therapeutics	52
Management of inflammation in cardiovascular diseases	52
Inflammation in Bipolar Disorder (BD): Identification of new therapeutic targets	52
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis	52
Targeting LSD1 for acute myeloid leukemia (AML) treatment	52
Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases	51
Loss of m6A methyltransferase METTL3 promotes heart regeneration and repair after myocardial injury	50
Relevance of the CXCR4/CXCR7-CXCL12 axis and its effect in pathophysiological conditions	50
Autophagy-related microRNAs: Possible regulatory roles and therapeutic potential in and gastrointestinal cancers	50
A bioinformatics analysis, pre-clinical and clinical conception of autophagy in pancreatic cancer: Complexity and simplicity in crosstalk	50
Orally effective FDA-approved protein kinase targeted covalent inhibitors (TCIs)	50
Polyphenols and atherosclerosis: A critical review of clinical effects on LDL oxidation	49
Clinical experience with CTLA-4 blockade for cancer immunotherapy: From the monospecific monoclonal antibody ipilimumab to probodies and bispecific molecules targeting the tumor microenvironment	49
Nonsteroidal mineralocorticoid receptor antagonism for cardiovascular and renal disorders − New perspectives for combination therapy	49
Roles of the peroxisome proliferator-activated receptors (PPARs) in the pathogenesis of nonalcoholic fatty liver disease (NAFLD)	49
Targeting gut barrier dysfunction with phytotherapies: Effective strategy against chronic diseases	49
Lactobacillus fermentum CECT5716 ameliorates high fat diet-induced obesity in mice through modulation of gut microbiota dysbiosis	48
Neutrophil extracellular traps in inflammatory bowel diseases: Implications in pathogenesis and therapeutic targets	48
Cell cycle checkpoints and beyond: Exploiting the ATR/CHK1/WEE1 pathway for the treatment of PARP inhibitor–resistant cancer	48
Corylin reduces obesity and insulin resistance and promotes adipose tissue browning through SIRT-1 and β3-AR activation	48
MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH	48
Stress induced microglial activation contributes to depression	48
Emerging pharmacotherapy for inflammatory bowel diseases	48
Regulation of ferroptosis by bioactive phytochemicals: Implications for medical nutritional therapy	47
Liver organoid as a 3D in vitro model for drug validation and toxicity assessment	47
Lipoprotein(a): Knowns, unknowns and uncertainties	47
Ursolic acid enhances the antitumor effects of sorafenib associated with Mcl-1-related apoptosis and SLC7A11-dependent ferroptosis in human cancer	47
Polyol pathway and redox balance in diabetes	47
TRIM21 – A potential novel therapeutic target in cancer	47
Improving the ability of CAR-T cells to hit solid tumors: Challenges and strategies	47
The cardioprotective actions of statins in targeting mitochondrial dysfunction associated with myocardial ischaemia-reperfusion injury	46
Metabolomics and integrated network pharmacology analysis reveal Tricin as the active anti-cancer component of Weijing decoction by suppression of PRKCA and sphingolipid signaling	46
Properties of FDA-approved small molecule protein kinase inhibitors: A 2024 update	46
Nuciferine, an active ingredient derived from lotus leaf, lights up the way for the potential treatment of obesity and obesity-related diseases	46
Sodium-glucose cotransporter-2 (SGLT2) expression in diabetic and non-diabetic failing human cardiomyocytes	46
Bioactivity of natural biflavonoids in metabolism-related disease and cancer therapies	46
Mitochondrial dysfunction and mitochondrial therapies in heart failure	46
The NLRP3 inflammasome in depression: Potential mechanisms and therapies	46

Dysbiosis is one of the risk factor for stroke and cognitive impairment and potential target for treatment	46
Targeting stress granules: A novel therapeutic strategy for human diseases	46
New frontiers against sorafenib resistance in renal cell carcinoma: From molecular mechanisms to predictive biomarkers	46
Neuroinflammation, oxidative stress and their interplay in neuropathic pain: Focus on specialized pro-resolving mediators and NADPH oxidase inhibitors as potential therapeutic strategies	45
Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment	45
Microbiota diversity in nonalcoholic fatty liver disease and in drug-induced liver injury	45
Current etiological comprehension and therapeutic targets of acetaminophen-induced hepatotoxicity	45
Epigenetic regulation in fibrosis progress	45
14-3-3 modulation of the inflammatory response	45
TLR4 and AT1R mediate blood-brain barrier disruption, neuroinflammation, and autonomic dysfunction in spontaneously hypertensive rats	45
Gut microbiota remodeling improves natural aging-related disorders through Akkermansia muciniphila and its derived acetic acid	45
NLRP3 inflammasome and IL-1β pathway in type 2 diabetes and atherosclerosis: Friend or foe?	45
Novel rapid-acting glutamatergic modulators: Targeting the synaptic plasticity in depression	45
Discovery of a novel short peptide with efficacy in accelerating the healing of skin wounds	44
MicroRNA targets and biomarker validation for diabetes-associated cardiac fibrosis	44
Pharmacological induction of mesenchymal-epithelial transition via inhibition of H2S biosynthesis and consequent suppression of ACLY activity in colon cancer cells	44
Polymyxin-induced nephrotoxicity and its predictors: a systematic review and meta-analysis of studies conducted using RIFLE criteria of acute kidney injury	44
FordNet: Recommending traditional Chinese medicine formula via deep neural network integrating phenotype and molecule	44
Natural tyrosine kinase inhibitors acting on the epidermal growth factor receptor: Their relevance for cancer therapy	44
The interaction between autophagy and neuroinflammation in major depressive disorder: From pathophysiology to therapeutic implications	44
Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review	43
SIRT3 as a potential therapeutic target for heart failure	43
Histone deacetylase 2 selective inhibitors: A versatile therapeutic strategy as next generation drug target in cancer therapy	43
Current and future therapeutic perspective in chronic heart failure	43
Janus kinase (JAK) inhibitors in the treatment of neoplastic and inflammatory disorders	43
The emerging roles of exosomes in autoimmune diseases, with special emphasis on microRNAs in exosomes	42
Pharmacological review of isobavachalcone, a naturally occurring chalcone	42
Berberine ameliorates ovariectomy-induced anxiety-like behaviors by enrichment in equol generating gut microbiota	42
Mitophagy enhancers against phosphorylated Tau-induced mitochondrial and synaptic toxicities in Alzheimer disease	42
Protective effect of isosteviol sodium against LPS-induced multiple organ injury by regulating of glycerophospholipid metabolism and reducing macrophage-driven inflammation	42
Aducanumab for Alzheimer’s disease: A regulatory perspective	42
Properties of FDA-approved small molecule phosphatidylinositol 3-kinase inhibitors prescribed for the treatment of malignancies	42
The effects of astaxanthin supplementation on obesity, blood pressure, CRP, glycemic biomarkers, and lipid profile: A meta-analysis of randomized controlled trials	42
Beyond Lipoprotein(a) plasma measurements: Lipoprotein(a) and inflammation	41
Development of PI3K inhibitors: Advances in clinical trials and new strategies (Review)	41
Hippocampal miR-206-3p participates in the pathogenesis of depression via regulating the expression of BDNF	41
Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy	41
Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models	41
Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway	40
Prospects of tangeretin as a modulator of cancer targets/pathways	40
Yin-xing-tong-mai decoction attenuates atherosclerosis via activating PPARγ-LXRα-ABCA1/ABCG1 pathway	40
Natural-derived alkaloids exhibit great potential in the treatment of ulcerative colitis	40
Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights	40
Effects of chromium supplementation on glycemic control in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials	40
Biological effects and mechanisms of matrine and other constituents of Sophora flavescens in colorectal cancer	39
Mitochondrial dysfunction and beneficial effects of mitochondria-targeted small peptide SS-31 in Diabetes Mellitus and Alzheimer’s disease	39
Toll-like receptors and metabolic (dysfunction)-associated fatty liver disease	39
Anxiolytic and antidepressive potentials of rosmarinic acid: A review with a focus on antioxidant and anti-inflammatory effects	39
Immunity and inflammation in pulmonary arterial hypertension: From pathophysiology mechanisms to treatment perspective	39
Traditional Chinese medicine in the treatment of nonalcoholic steatohepatitis	39
Phytochemicals as regulators of microglia/macrophages activation in cerebral ischemia	39
The impact of glutathione metabolism in autism spectrum disorder	38
In silico development and clinical validation of novel 8 gene signature based on lipid metabolism related genes in colon adenocarcinoma	38
The gut-lung axis in severe acute Pancreatitis-associated lung injury: The protection by the gut microbiota through short-chain fatty acids	38
Alpinetin ameliorates bone loss in LPS-induced inflammation osteolysis via ROS mediated P38/PI3K signaling pathway	38
Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice	38
Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics	38
Advances in targeted therapy for osteosarcoma based on molecular classification	38
Flavonoids regulate tumor-associated macrophages – From structure-activity relationship to clinical potential (Review)	38
Hanshiyi Formula, a medicine for Sars-CoV2 infection in China, reduced the proportion of mild and moderate COVID-19 patients turning to severe status: A cohort study	38
Endoplasmic reticulum stress promotes breast cancer cells to release exosomes circ_0001142 and induces M2 polarization of macrophages to regulate tumor progression	38
Berberine for gastric cancer prevention and treatment: Multi-step actions on the Correa’s cascade underlie its therapeutic effects	37
Old wine in new bottles: Kaempferol is a promising agent for treating the trilogy of liver diseases	37
Resveratrol-mediated attenuation of superantigen-driven acute respiratory distress syndrome is mediated by microbiota in the lungs and gut	37
Didymin switches M1-like toward M2-like macrophage to ameliorate ulcerative colitis via fatty acid oxidation	37
Mechanistic insights into AMPK-SIRT3 positive feedback loop-mediated chondrocyte mitochondrial quality control in osteoarthritis pathogenesis	37
Prevention and management of idiosyncratic drug-induced liver injury: Systematic review and meta-analysis of randomised clinical trials	37
Emerging roles of neutrophil-borne S100A8/A9 in cardiovascular inflammation	37
Meta-analysis on outcome-worsening comorbidities of COVID-19 and related potential drug-drug interactions	37
Progress in the treatment of drug-induced liver injury with natural products	37
Development and clinical validation of a novel 9-gene prognostic model based on multi-omics in pancreatic adenocarcinoma	37
Triptolide delivery: Nanotechnology-based carrier systems to enhance efficacy and limit toxicity	37
Therapeutic potential of broccoli-derived extracellular vesicles as nanocarriers of exogenous miRNAs	37
Elabela ameliorates doxorubicin-induced cardiotoxicity by promoting autophagic flux through TFEB pathway	36
αKlotho protein has therapeutic activity in contrast-induced acute kidney injury by limiting NLRP3 inflammasome-mediated pyroptosis and promoting autophagy	36
Lycorine improves peripheral nerve function by promoting Schwann cell autophagy via AMPK pathway activation and MMP9 downregulation in diabetic peripheral neuropathy	36
Pre-clinical and clinical importance of miR-21 in human cancers: Tumorigenesis, therapy response, delivery approaches and targeting agents	36
Fourteen composite probiotics alleviate type 2 diabetes through modulating gut microbiota and modifying M1/M2 phenotype macrophage in db/db mice	36
Molecular mechanisms of mitophagy and its roles in neurodegenerative diseases	36
Adipokines as a therapeutic target by metformin to improve metabolic function: A systematic review of randomized controlled trials	36
Deciphering the cellular mechanisms underlying fibrosis-associated diseases and therapeutic avenues	36
A sweet spot for macrophages: Focusing on polarization	36
Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain	36
The potency of heterocyclic curcumin analogues: An evidence-based review	35
International policies and challenges on the legalization of traditional medicine/herbal medicines in the fight against COVID-19	35
Ginsenosides for cardiovascular diseases; update on pre-clinical and clinical evidence, pharmacological effects and the mechanisms of action	35
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Where will the drugs come from?	35
Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors	35
The role of androgens in women's health and wellbeing	35
Cytisine and cytisine derivatives. More than smoking cessation aids	35
Challenges of BDNF-based therapies: From common to rare diseases	35
Protein-polysaccharide interactions for the fabrication of bioactive-loaded nanocarriers: Chemical conjugates and physical complexes	34
Salvianolic acid A relieves cognitive disorder after chronic cerebral ischemia: Involvement of Drd2/Cryab/NF-κB pathway	34
Bufalin for an innovative therapeutic approach against cancer	34
The natural product berberine synergizes with osimertinib preferentially against MET-amplified osimertinib-resistant lung cancer via direct MET inhibition	34