Pharmacological Research

Papers
(The H4-Index of Pharmacological Research is 68. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
The role of short-chain fatty acids in intestinal barrier function, inflammation, oxidative stress, and colonic carcinogenesis328
The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders323
Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance280
Properties of FDA-approved small molecule protein kinase inhibitors: A 2021 update257
Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms206
Chemical constituents of Panax ginseng and Panax notoginseng explain why they differ in therapeutic efficacy194
The impact of the microbiota-gut-brain axis on Alzheimer’s disease pathophysiology172
Hydrogen sulfide: An endogenous regulator of the immune system172
Ferroptosis and its emerging roles in cardiovascular diseases157
Properties of FDA-approved small molecule protein kinase inhibitors: A 2022 update156
Efficacy of Huoxiang Zhengqi dropping pills and Lianhua Qingwen granules in treatment of COVID-19: A randomized controlled trial153
Properties of FDA-approved small molecule protein kinase inhibitors: A 2023 update151
Necrostatin-1 and necroptosis inhibition: Pathophysiology and therapeutic implications145
Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells145
Cucurbitacin B inhibits non-small cell lung cancer in vivo and in vitro by triggering TLR4/NLRP3/GSDMD-dependent pyroptosis144
New progress in the pharmacology of protocatechuic acid: A compound ingested in daily foods and herbs frequently and heavily143
Skeletal muscle atrophy: From mechanisms to treatments138
HDAC6 as privileged target in drug discovery: A perspective132
Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative review131
Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis131
The hormetic dose-response mechanism: Nrf2 activation126
Nuclear receptor coactivator 4-mediated ferritinophagy contributes to cerebral ischemia-induced ferroptosis in ischemic stroke125
Main active components of Jiawei Gegen Qinlian decoction protects against ulcerative colitis under different dietary environments in a gut microbiota-dependent manner120
“Therapeutic uses of natural astaxanthin: An evidence-based review focused on human clinical trials”120
RNA methylation and cancer treatment117
Lactobacillus acidophilus ameliorates obesity in mice through modulation of gut microbiota dysbiosis and intestinal permeability113
Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer110
Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects110
Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites110
Prospective therapeutic potential of Tanshinone IIA: An updated overview106
Resveratrol and endothelial function: A literature review104
Dioscin ameliorates murine ulcerative colitis by regulating macrophage polarization103
Regulation of blood-retinal barrier cell-junctions in diabetic retinopathy102
The anti-inflammatory and immunological properties of GLP-1 Receptor Agonists100
Natural volatile oils derived from herbal medicines: A promising therapy way for treating depressive disorder99
Dihydromyricetin improves DSS-induced colitis in mice via modulation of fecal-bacteria-related bile acid metabolism98
Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis98
Perspective on the application of medicinal plants and natural products in wound healing: A mechanistic review94
Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance94
Lupeol and its derivatives as anticancer and anti-inflammatory agents: Molecular mechanisms and therapeutic efficacy94
Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications93
Long noncoding RNA p21 enhances autophagy to alleviate endothelial progenitor cells damage and promote endothelial repair in hypertension through SESN2/AMPK/TSC2 pathway92
Metabolic reprogramming by traditional Chinese medicine and its role in effective cancer therapy92
Naringenin is a powerful inhibitor of SARS-CoV-2 infection in vitro90
The Nrf2 in the pathophysiology of the intestine: Molecular mechanisms and therapeutic implications for inflammatory bowel diseases90
Chloroquine and hydroxychloroquine in antitumor therapies based on autophagy-related mechanisms90
Anti-diabetic drugs and weight loss in patients with type 2 diabetes87
Current Policies and Measures on the Development of Traditional Chinese Medicine in China87
EGFR mutation mediates resistance to EGFR tyrosine kinase inhibitors in NSCLC: From molecular mechanisms to clinical research86
Urolithin A suppresses RANKL-induced osteoclastogenesis and postmenopausal osteoporosis by, suppresses inflammation and downstream NF-κB activated pyroptosis pathways85
The current use and evolving landscape of nutraceuticals84
Baicalin mediated regulation of key signaling pathways in cancer84
Tumor-associated macrophages: A promising target for a cancer immunotherapeutic strategy83
Epigenetics in NAFLD/NASH: Targets and therapy80
Apoptosis, autophagy and atherosclerosis: Relationships and the role of Hsp2780
Endoplasmic reticulum stress in doxorubicin-induced cardiotoxicity may be therapeutically targeted by natural and chemical compounds: A review79
Reproductive toxic potential of phthalate compounds – State of art review77
MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis76
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy74
Sesquiterpenes and their derivatives-natural anticancer compounds: An update73
Acute kidney injury is associated with severe infection and fatality in patients with COVID-19: A systematic review and meta-analysis of 40 studies and 24,527 patients72
Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach72
STAT3-EMT axis in tumors: Modulation of cancer metastasis, stemness and therapy response72
Endoplasmic reticulum stress and protein degradation in chronic liver disease69
BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection69
Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases68
Elucidation of the anti-inflammatory mechanism of Er Miao San by integrative approach of network pharmacology and experimental verification68
Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway68
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