OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Endocrinology and Metabolism is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Cellular mechanism of diabetes remission by bariatric surgery	413
Maternal metabolism influences neural tube closure	363
Emerging roles of N-linked glycosylation in brain physiology and disorders	298
The changing clinical spectrum of endocrine adverse events in cancer immunotherapy	220
Mechanisms of kidney fibrosis and routes towards therapy	170
Contribution of metabolism-independent glucose sensing to metabolic homeostasis	167
Irisin limits amyloid-β buildup in Alzheimer’s disease	135
How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination	119
Advisory Board and Contents	112
N6-methyladenosine RNA modification in nonalcoholic fatty liver disease	105
Advisory Board and Contents	105
Subscription and Copyright Information	104
Establishing evidence for immune surveillance of β-cell senescence	93
Advisory Board and Contents	88
Unveiling the cancer risk nexus of the steatotic liver	86
Methionine restriction and mimetics to ameliorate human aging and disease	84
Neuroendocrine gut–brain signaling in obesity	83
Cannabinoids and terpenes for diabetes mellitus and its complications: from mechanisms to new therapies	82
Healthy choices, healthy futures: promoting healthy nutrition to curb non-communicable diseases	81
Uridine	77
Advisory Board and Contents	75
Subscription and Copyright Information	74
Dietary medium-chain triacylglycerols in metabolic regulation	73
Why cells need iron: a compendium of iron utilisation	73
Increased hepatic gluconeogenesis and type 2 diabetes mellitus	72

A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring	71
Enhancer binding as a KEysTONE of fasting response	69
A metabolic perspective on cuproptosis	63
A double-edged sword: risks and benefits of heat for human health	63
Mechanomedicine targeting brown adipose tissue for metabolic health	60
A multidimensional epidemiological perspective on frailty dynamics and prevention	59
Is high-intensity interval training harmful to health?	58
Effects of APOE4 on omega-3 brain metabolism across the lifespan	57
Liver-expressed antimicrobial peptide 2 (LEAP2)	56
CD8+ T cell stressors converge on shared metabolic–epigenetic networks	55
Parathyroid hormone–PTH1R signaling in cardiovascular disease and homeostasis	51
Subscription and Copyright Information	50
The landscape of fetus metabolism in maternal hyperglycemia	48
Metabolic challengers selecting tumor-persistent cells	47
Subscription and Copyright Information	46
GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?	46
Advisory Board and Contents	45
Drosophila as a diet discovery tool for treating amino acid disorders	45
Subscription and Copyright Information	44
‘Rotor free-wheeling’ in impaired F1FO-ATPase induces congenital hypermetabolism	44
Metabolic remodeling in cancer and senescence and its therapeutic implications	43
Current status and future perspectives of FGF21 analogues in clinical trials	43
Beta-hydroxybutyrate	43
Olfactory system and energy metabolism: a two-way street	42
Metabolism, homeostasis, and aging	42
Sepsis: a failing starvation response	40
Targeting cholesterol-dependent adrenal steroidogenesis for management of primary aldosteronism	38
Can kisspeptin be a new treatment for sexual dysfunction?	38
Advisory Board and Contents	38
Balancing metabolism and regeneration in liver diseases through HNF4α targeting	37
Exercise pills for cardiometabolic health cannot mimic the exercise milieu	37
Hallmarks of the metabolic secretome	36
Serine signaling governs metabolic homeostasis and health	36
The interplay between endometriosis and obesity	36
Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses	35
New tools for bone health assessment in secreting pituitary adenomas	35
Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic–pituitary–ovarian axis	34
Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts	33
Lipid-associated macrophages between aggravation and alleviation of metabolic diseases	32
Amino acid transporters as modulators of glucose homeostasis	32
Mitochondrial copper in human genetic disorders	32
B vitamins as adjunct therapies for depressive disorder	31
Gut microbiota and eating behaviour in circadian syndrome	31
Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease	31
Advisory Board and Contents	30
A three-layer perspective on miRNA regulation in β cell inflammation	30
Shifting metabolism to increase lifespan	30
Pericytic porters: helping leptin step in	30
Advisory Board and Contents	30
Exercised breastmilk: a kick-start to prevent childhood obesity?	29

Rewiring of the glymphatic landscape in metabolic disorders	29
Shared metabolic and stress pathways to neonatal adiposity	29
Advisory Board and Contents	28
Metabolic-immune microenvironment crosstalk mediating ICI resistance in MASH-HCC	28
Cardioprotective benefits of metabolic surgery and GLP-1 receptor agonist–based therapies	28
Insights from omics research on plant-based diets and cardiometabolic health	27
Mitochondria as sensors of intracellular pathogens	27
(Poly)phenols as bioactive constituents linked to dietary fibre metabolic fate	26
An epidemiological introduction to human metabolomic investigations	26
The physiological functions of lymphangiocrine signals	26
Gut microbiota controlling radiation-induced enteritis and intestinal regeneration	26
Recompensation in MASLD-related cirrhosis via metabolic bariatric surgery	26
Creating a picture of brown fat with creatine-CEST	25
More trials for the unhappy hypothyroid patient on thyroxine: a clinician’s perspective	25
The sphinx helps to answer the riddle of cardiac regeneration	25
Metabolic consequences of sleep and circadian disruption during pregnancy and postpartum	24
Subscription and Copyright Information	23
Dopamine	23
Exploring tryptophan metabolism in cardiometabolic diseases	22
Wildfires and COVID-19: syndemic impact on maternal and child health	22
Metabolic homeostasis of tissue macrophages across the lifespan	22
Cortisol and cardiometabolic disease: a target for advancing health equity	22
Road map for personalized exercise medicine in T2DM	22
Spatiotemporal coordination between local flux and systemic homeostasis in the small intestine	22
Detection, mechanisms, and therapeutic implications of oncometabolites	22
Endoscopic management of obesity and metabolic diseases	22
Etherglycerophospholipids and ferroptosis: structure, regulation, and location	21
Subscription and Copyright Information	21
Subscription and Copyright Information	21
Targeting systemic and gut microbial metabolism in ER+ breast cancer	21
Gut feelings on short-chain fatty acids to regulate respiratory health	20
The relationship between CD4+ T cell glycolysis and their functions	20
Subscription and Copyright Information	20
Systemic and organ-specific anti-inflammatory effects of sodium-glucose cotransporter-2 inhibitors	20
Assessment and treatment of osteoporosis and fractures in type 2 diabetes	20
Dietary and pharmacological energy restriction and exercise for healthspan extension	20
Understanding lactate sensing and signalling	20
The time is now for new, lower diabetes diagnostic thresholds	20
Melatonin	20
An orphan to the rescue of obesity and steatotic liver?	20
Apolipoprotein E in lipid metabolism and neurodegenerative disease	20
Rethinking ‘normal’: are pubertal milestones and growth charts obsolete?	20
Mitochondrial quality control pathways sense mitochondrial protein import	19
Decoding microbial volatile signals in host–microbiome crosstalk	19
The impact of epitranscriptomic modifications on liver disease	19
Subscription and Copyright Information	19
Insulin	18
NAD augmentation as a disease-modifying strategy for neurodegeneration	18
Early nutritional interventions for chronic low-grade inflammation	18
Glucokinase activity in diabetes: too much of a good thing?	18
SARS-CoV-2 and pancreas: a potential pathological interaction?	17
Neural stem cell metabolism revisited: a critical role for mitochondria	17
Subscription and Copyright Information	17
GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism	17
SIRT6: therapeutic target for nonalcoholic fatty liver disease	17
Information theory in vertebrate stress physiology	16
Crotonyl-coenzyme A (crotonyl-CoA)	16
Regulated cell death in myocardial ischemia–reperfusion injury	16
Pathophysiology of human mitochondrial tRNA metabolism	16
Advisory Board and Contents	16
Pancreatic islet adaptation in pregnancy and postpartum	16
Is MASLD lost in translation in mice?	16
Integrating cancer medicine into metabolic rhythms	16
Microglial metabolic flexibility: emerging roles for lactate	16