OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Endocrinology and Metabolism is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Advisory Board and Contents	324
Advisory Board and Contents	303
Advisory Board and Contents	265
N6-methyladenosine RNA modification in nonalcoholic fatty liver disease	172
How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination	152
Establishing evidence for immune surveillance of β-cell senescence	151
Advisory Board and Contents	104
Cellular mechanism of diabetes remission by bariatric surgery	101
Metabolic hallmarks of liver regeneration	100
Subscription and Copyright Information	91
Irisin limits amyloid-β buildup in Alzheimer’s disease	89
The changing clinical spectrum of endocrine adverse events in cancer immunotherapy	85
Neuroendocrine gut–brain signaling in obesity	78
Unveiling the cancer risk nexus of the steatotic liver	78
Maternal metabolism influences neural tube closure	78
Cannabinoids and terpenes for diabetes mellitus and its complications: from mechanisms to new therapies	76
Emerging roles of N-linked glycosylation in brain physiology and disorders	75
Mechanisms of kidney fibrosis and routes towards therapy	74
Advisory Board and Contents	73
Subscription and Copyright Information	73
Subscription and Copyright Information	69
Healthy choices, healthy futures: promoting healthy nutrition to curb non-communicable diseases	65
Jekyll and Hyde: nuclear receptors ignite and extinguish hepatic oxidative milieu	63
Uridine	62
A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring	60

Why cells need iron: a compendium of iron utilisation	59
Increased hepatic gluconeogenesis and type 2 diabetes mellitus	57
Advisory Board and Contents	57
Subscription and Copyright Information	56
Liver-expressed antimicrobial peptide 2 (LEAP2)	56
Fruitful futures for reproductive health	56
Enhancer binding as a KEysTONE of fasting response	56
Subscription and Copyright Information	56
Subscription and Copyright Information	53
Is high-intensity interval training harmful to health?	53
Parathyroid hormone–PTH1R signaling in cardiovascular disease and homeostasis	51
GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?	51
‘Rotor free-wheeling’ in impaired F1FO-ATPase induces congenital hypermetabolism	51
The landscape of fetus metabolism in maternal hyperglycemia	46
Olfactory system and energy metabolism: a two-way street	45
Sex hormone–binding globulin: biomarker and hepatokine?	44
Metabolism, homeostasis, and aging	44
A metabolic perspective on cuproptosis	44
Beta-hydroxybutyrate	44
Effects of APOE4 on omega-3 brain metabolism across the lifespan	43
Current status and future perspectives of FGF21 analogues in clinical trials	42
Drosophila as a diet discovery tool for treating amino acid disorders	40
Metabolic challengers selecting tumor-persistent cells	40
A double-edged sword: risks and benefits of heat for human health	39
Metabolic remodeling in cancer and senescence and its therapeutic implications	39
Sepsis: a failing starvation response	38
A multidimensional epidemiological perspective on frailty dynamics and prevention	38
Hallmarks of the metabolic secretome	37
Advisory Board and Contents	37
Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses	37
The interplay between endometriosis and obesity	36
Can kisspeptin be a new treatment for sexual dysfunction?	36
New tools for bone health assessment in secreting pituitary adenomas	35
Serine signaling governs metabolic homeostasis and health	35
Fructose-1,6-bisphosphate promotes PI3K and glycolysis in T cells?	33
Targeting cholesterol-dependent adrenal steroidogenesis for management of primary aldosteronism	33
Gut microbiota and eating behaviour in circadian syndrome	32
Lipid-associated macrophages between aggravation and alleviation of metabolic diseases	32
Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts	32
Mitochondrial copper in human genetic disorders	32
Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic–pituitary–ovarian axis	31
Amino acid transporters as modulators of glucose homeostasis	31
Balancing metabolism and regeneration in liver diseases through HNF4α targeting	31
Advisory Board and Contents	30
Advisory Board and Contents	30
Rewiring of the glymphatic landscape in metabolic disorders	30
Exercised breastmilk: a kick-start to prevent childhood obesity?	29
A three-layer perspective on miRNA regulation in β cell inflammation	29
Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease	29
Shifting metabolism to increase lifespan	29

Thyroid wars: the rise of central actions	28
Pericytic porters: helping leptin step in	28
B vitamins as adjunct therapies for depressive disorder	28
(Poly)phenols as bioactive constituents linked to dietary fibre metabolic fate	27
Shared metabolic and stress pathways to neonatal adiposity	27
Cardioprotective benefits of metabolic surgery and GLP-1 receptor agonist–based therapies	27
Advisory Board and Contents	27
More trials for the unhappy hypothyroid patient on thyroxine: a clinician’s perspective	26
The physiological functions of lymphangiocrine signals	26
Why equalising HIIT and MICT is important: attention to methodological details	26
Insights from omics research on plant-based diets and cardiometabolic health	26
Metabolic-immune microenvironment crosstalk mediating ICI resistance in MASH-HCC	25
Mitochondria as sensors of intracellular pathogens	25
Recompensation in MASLD-related cirrhosis via metabolic bariatric surgery	24
An epidemiological introduction to human metabolomic investigations	24
Subscription and Copyright Information	24
Gut microbiota controlling radiation-induced enteritis and intestinal regeneration	24
Subscription and Copyright Information	23
The sphinx helps to answer the riddle of cardiac regeneration	23
Subscription and Copyright Information	23
Wildfires and COVID-19: syndemic impact on maternal and child health	23
Metabolic consequences of sleep and circadian disruption during pregnancy and postpartum	22
Exploring tryptophan metabolism in cardiometabolic diseases	22
Creating a picture of brown fat with creatine-CEST	22
Targeting systemic and gut microbial metabolism in ER+ breast cancer	21
Etherglycerophospholipids and ferroptosis: structure, regulation, and location	21
Road map for personalized exercise medicine in T2DM	21
Cortisol and cardiometabolic disease: a target for advancing health equity	20
Dopamine	20
The ubiquitin-proteasome system and autophagy: self-digestion for metabolic health	20
Endoscopic management of obesity and metabolic diseases	20
The emerging role of metabolism in fibrosis	20
Metabolic homeostasis of tissue macrophages across the lifespan	19
Detection, mechanisms, and therapeutic implications of oncometabolites	19
Corticosteroid receptors as a model for the Hsp90•immunophilin-based transport machinery	19
Melatonin	18
An orphan to the rescue of obesity and steatotic liver?	18
Gut feelings on short-chain fatty acids to regulate respiratory health	18
The time is now for new, lower diabetes diagnostic thresholds	18
Dietary lipids as regulators of reward processes: multimodal integration matters	17
Dietary and pharmacological energy restriction and exercise for healthspan extension	17
Understanding lactate sensing and signalling	17
The relationship between CD4+ T cell glycolysis and their functions	17
Systemic and organ-specific anti-inflammatory effects of sodium-glucose cotransporter-2 inhibitors	17
Apolipoprotein E in lipid metabolism and neurodegenerative disease	17
Assessment and treatment of osteoporosis and fractures in type 2 diabetes	17
Subscription and Copyright Information	16
SARS-CoV-2 and pancreas: a potential pathological interaction?	16
Insulin	16
Early nutritional interventions for chronic low-grade inflammation	16
Subscription and Copyright Information	16
Pancreatic islet adaptation in pregnancy and postpartum	16
NAD augmentation as a disease-modifying strategy for neurodegeneration	16
Subscription and Copyright Information	16
GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism	15
Glucokinase activity in diabetes: too much of a good thing?	15
Osteomorphs as a tool for personalized medicine	15
Neural stem cell metabolism revisited: a critical role for mitochondria	15
The impact of epitranscriptomic modifications on liver disease	15
Mitochondrial quality control pathways sense mitochondrial protein import	15
Subscription and Copyright Information	15
SIRT6: therapeutic target for nonalcoholic fatty liver disease	15
Microglial metabolic flexibility: emerging roles for lactate	15
Regulated cell death in myocardial ischemia–reperfusion injury	15
Subscription and Copyright Information	15