Trends in Endocrinology and Metabolism

Article	Citations
Gut barrier disruption and chronic disease	222
Ferritinophagy and ferroptosis in the management of metabolic diseases	198
Gut Microbial Metabolites of Aromatic Amino Acids as Signals in Host–Microbe Interplay	197
Butyrate in Energy Metabolism: There Is Still More to Learn	175
The menace of obesity to depression and anxiety prevalence	159
Cardiolipin, Mitochondria, and Neurological Disease	151
Amino Acid Depletion Therapies: Starving Cancer Cells to Death	149
Links between metabolic syndrome and metabolic dysfunction-associated fatty liver disease	113
Lipoprotein Lipase and Its Regulators: An Unfolding Story	108
The membrane receptor CD44: novel insights into metabolism	97
Insights Into Mechanisms of GDF15 and Receptor GFRAL: Therapeutic Targets	95
Long COVID: pathophysiological factors and abnormalities of coagulation	82
Stress-induced FGF21 and GDF15 in obesity and obesity resistance	74
Current status and future trends of the global burden of MASLD	71
Blood Microbiota and Circulating Microbial Metabolites in Diabetes and Cardiovascular Disease	70
Targeting aging mechanisms: pharmacological perspectives	64
Nrf2: The Master and Captain of Beta Cell Fate	63
Emerging roles for folate receptor FOLR1 in signaling and cancer	60
Roles of TGF-β Superfamily Proteins in Extravillous Trophoblast Invasion	58
Alpha-Ketoglutarate dietary supplementation to improve health in humans	57
Rethinking succinate: an unexpected hormone-like metabolite in energy homeostasis	54
Cardiovascular Manifestations and Mechanisms in Patients with COVID-19	51
Microglial metabolic flexibility: emerging roles for lactate	51
Flavonoids in Bone Erosive Diseases: Perspectives in Osteoporosis Treatment	49
Emerging roles of N-linked glycosylation in brain physiology and disorders	49

Sexual Dimorphism of Coronavirus 19 Morbidity and Lethality	46
Understanding lactate sensing and signalling	46
Metabolic homeostasis via BDNF and its receptors	46
Skin Metabolomics	46
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline	45
Metabolic changes favor the activity and heterogeneity of reactive astrocytes	45
Role of Medium-Chain Fatty Acids in Healthy Metabolism: A Clinical Perspective	45
Sex and COVID-19: A Protective Role for Reproductive Steroids	44
Assessment and treatment of osteoporosis and fractures in type 2 diabetes	43
Sex hormone–binding globulin: biomarker and hepatokine?	42
Sepsis: a failing starvation response	42
The emerging role of metabolism in fibrosis	41
OPA1 regulation of mitochondrial dynamics in skeletal and cardiac muscle	41
Mitochondrial copper in human genetic disorders	41
Role of Macrophages in the Endocrine System	40
Apolipoprotein E in lipid metabolism and neurodegenerative disease	39
Melatonin: A Potential Therapeutic Option for Breast Cancer	39
Gut and vaginal microbiomes on steroids: implications for women’s health	38
Insulin resistance in cardiovascular disease, uremia, and peritoneal dialysis	37
Reframing anorexia nervosa as a metabo-psychiatric disorder	37
Intestinal Organoids: A Tool for Modelling Diet–Microbiome–Host Interactions	36
FKBP51 and the molecular chaperoning of metabolism	36
Irisin, a fascinating field in our times	35
Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic–pituitary–ovarian axis	35
One carbon metabolism and early development: a diet-dependent destiny	35
GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism	35
Lipids and lipoproteins in cardiovascular diseases: a classification	35
The impact of metal availability on immune function during infection	34
Mechanisms of lipid metabolism in uterine receptivity and embryo development	34
Metabolic hallmarks of liver regeneration	33
Effects of Blood Flow Restriction Exercise and Possible Applications in Type 2 Diabetes	33
Efficacy evaluation, active ingredients, and multitarget exploration of herbal medicine	33
Metabolic disorders on cognitive dysfunction after traumatic brain injury	32
SGLT-2 inhibitors and GLP-1 receptor agonists in metabolic dysfunction-associated fatty liver disease	32
Regulated cell death in myocardial ischemia–reperfusion injury	31
Juggling with lipids, a game of Russian roulette	31
Cancer-Mediated Muscle Cachexia: Etiology and Clinical Management	29
Ketone bodies for the failing heart: fuels that can fix the engine?	29
Apolipoprotein E Effects on Mammalian Ovarian Steroidogenesis and Human Fertility	29
Autologous Platelet-Rich Plasma for Diabetic Foot Ulcer	28
Sex differences in Alzheimer’s disease: metabolic reprogramming and therapeutic intervention	28
Transcriptional mechanisms of pancreatic β-cell maturation and functional adaptation	28
Contributions of physical inactivity and sedentary behavior to metabolic and endocrine diseases	27
COVID-19 and obesity: fighting two pandemics with intermittent fasting	27
Nutritional Control of Intestinal Stem Cells in Homeostasis and Tumorigenesis	26
Confection Confusion: Interplay Between Diet, Taste, and Nutrition	26
Of ‘junk food’ and ‘brain food’: how parental diet influences offspring neurobiology and behaviour	26
High-Intensity Interval Training: Methodological Considerations for Interpreting Results and Conducting Research	26
NAFLD and thyroid function: pathophysiological and therapeutic considerations	25
SARS-CoV-2 and pancreas: a potential pathological interaction?	25

Amino acid transporters as modulators of glucose homeostasis	25
Non-flavonoid polyphenols in osteoporosis: preclinical evidence	24
Effects of Medical Treatment of Prostate Cancer on Bone Health	24
Old Paradoxes and New Opportunities for Appetite Control in Obesity	24
Contributors to impaired bone health in type 2 diabetes	24
Diet- and microbiota-related metabolite, 5-aminovaleric acid betaine (5-AVAB), in health and disease	24
Immune–metabolic interactions in homeostasis and the progression to NASH	24
Information theory in vertebrate stress physiology	24
Lipophagy: a new player in CNS disorders	24
MANF: an emerging therapeutic target for metabolic diseases	23
Glucokinase activity in diabetes: too much of a good thing?	22
Acetyl-CoA and Metabolite Fluxes Regulate White Adipose Tissue Expansion	22
Eukaryotic lipid droplets: metabolic hubs, and immune first responders	21
Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency	21
Advanced glycation endproducts in diabetes-related macrovascular complications: focus on methylglyoxal	21
From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI	21
Altered Cholesterol and Lipid Synthesis Mediates Hyperinflammation in COVID-19	20
Muscle Lipid Droplets: Cellular Signaling to Exercise Physiology and Beyond	20
ncRNA-mediated fatty acid metabolism reprogramming in HCC	20
COVID-19 and Metabolic Syndrome: NF-κB Activation. Crossroads	20
Knocking on GDF15’s door for the treatment of type 2 diabetes mellitus	19
The exercise IL-6 enigma in cancer	19
Time for Novel Strategies to Mitigate Cardiometabolic Risk in Shift Workers	19
Notch signaling in reproduction	19
Metabolism, homeostasis, and aging	19
Dietary lipids as regulators of reward processes: multimodal integration matters	19
Tissue engineering and 3D printing of bioartificial pancreas for regenerative medicine in diabetes	19
Gut microbiota controlling radiation-induced enteritis and intestinal regeneration	18
N6-methyladenosine in macrophage function: a novel target for metabolic diseases	18
Thyroid wars: the rise of central actions	18
Hexose Transporters in Cancer: From Multifunctionality to Diagnosis and Therapy	18
Growth Hormone Releasing Hormone in Endothelial Barrier Function	18
Neurological aspects of SARS-CoV-2 infection: lipoproteins and exosomes as Trojan horses	17
Hexokinase domain-containing protein-1 in metabolic diseases and beyond	17
Olfactory system and energy metabolism: a two-way street	17
Endocrine Factors in Key Structural and Intracellular Changes in Depression	17
Bird evolution by insulin resistance	17
Autoantibody-Negative Type 1 Diabetes: A Neglected Subtype	16
Pathophysiology and histopathology of primary aldosteronism	16
Many or too many progesterone membrane receptors? Clinical implications	15
New perspectives on sex differences in learning and memory	15
Bone marrow adipose tissue in metabolic health	15
Extracellular vesicle-mediated interorgan communication in metabolic diseases	15
Cortisol and cardiometabolic disease: a target for advancing health equity	15
Digesting recent findings: gut alpha-synuclein, microbiome changes in Parkinson’s disease	15
Terpenoid treatment in osteoporosis: this is where we have come in research	15
Neural and behavioral plasticity across the female reproductive cycle	14
ASCs and their role in obesity and metabolic diseases	14
Integrating metabolic reprogramming and metabolic imaging to predict breast cancer therapeutic responses	14
Sitagliptin/Metformin: A New Medical Treatment in Polycystic Ovary Syndrome	14
Influence of the gut microbiota on satiety signaling	13
The ubiquitin-proteasome system and autophagy: self-digestion for metabolic health	13
Novel Strategies to Protect and Visualize Pancreatic β Cells in Diabetes	13
The changing clinical spectrum of endocrine adverse events in cancer immunotherapy	13
Eosinophilia in cancer and its regulation by sex hormones	12
First-phase insulin secretion: can its evaluation direct therapeutic approaches?	12
Inflammaging: mechanisms and role in the cardiac and vasculature	12
Corticosteroid receptors as a model for the Hsp90•immunophilin-based transport machinery	12
Serine signaling governs metabolic homeostasis and health	12
Questioning PCOS phenotypes for reclassification and tailored therapy	12
Regulation of mTOR by phosphatidic acid	12
Integration of androgen hormones in endometrial cancer biology	12
Iron metabolism and atherosclerosis	11
Energy as the cornerstone of environmentally driven sex allocation	11
Gonadotropins as pharmacological agents in assisted reproductive technology and polycystic ovary syndrome	11
Myo-inositol in assisted reproductive technology from bench to bedside	11
Neural stem cell metabolism revisited: a critical role for mitochondria	11
Treatment of hypothyroidism in infants, children and adolescents	11
Sex steroids and COVID-19 mortality in women	11
Metabolic oscillations during cell-cycle progression	11
Growth Hormone Modulation of Hepatic Epidermal Growth Factor Receptor Signaling	10
Metabolic control by AMPK in white adipose tissue	10
Blood factors as biomarkers in osteoporosis: points from the COVID-19 era	10
Vitamin D toxicity related to its physiological and unphysiological supply	10
Mechanisms of kidney fibrosis and routes towards therapy	10
IBD Microbial Metabolome: The Good, Bad, and Unknown	9
The relationship between CD4+ T cell glycolysis and their functions	9
From Pharmacology to Physiology: Endocrine Functions of μ-Opioid Receptor Networks	9
Cannabinoids and terpenes for diabetes mellitus and its complications: from mechanisms to new therapies	9
Caudamins, a new subclass of protein hormones	9

A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring	9
Location matters: hexokinase 1 in glucose metabolism and inflammation	9
Fructose-1,6-bisphosphate promotes PI3K and glycolysis in T cells?	9
Growth variations with opposite clinical outcomes and the emerging role of IGF-1	9
Free radicals and antioxidants: appealing to magic	9
A two-front nutritional environment fuels colorectal cancer: perspectives for dietary intervention	8
Cytokines and exosomal miRNAs in skeletal muscle–adipose crosstalk	8
New tools for bone health assessment in secreting pituitary adenomas	8
Corticosteroid-binding globulin (CBG): spatiotemporal distribution of cortisol in sepsis	8
Key Metabolic Functions of β-Arrestins: Studies with Novel Mouse Models	8
Lysosomal glucose sensing and glycophagy in metabolism	8
New prebiotics by ketone donation	8
Etherglycerophospholipids and ferroptosis: structure, regulation, and location	8
Taurine Makes Our Microbiota Stronger	8
Dietary fat: a potent microglial influencer	8
Unconventional roles of lactate along the tumor and immune landscape	7
A Decade Later: Revisiting the TGFβ Family’s Role in Diabetes	7
Detection, mechanisms, and therapeutic implications of oncometabolites	7
Ghrelin receptor signaling in health and disease: a biased view	7
Lessons from neonatal β-cell epigenomic for diabetes prevention and treatment	7
GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?	7
Fructose 1-phosphate, an evolutionary signaling molecule of abundancy	7
Peripheral neurovascular link: an overview of interactions and in vitro models	7
Placental inflammation, oxidative stress, and fetal outcomes in maternal obesity	7
Alternate-day fasting exacerbates doxorubicin cardiotoxicity in cancer chemotherapy	7
Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis?	7
The emerging role of bile acids in white adipose tissue	7
Regulatory networks determining substrate utilization in brown adipocytes	7
A clinical perspective on ectopic Cushing’s syndrome	6
Those Apples Don’t Taste Like Oranges! Why ‘Equalising’ HIIT and MICT Protocols Does Not Make Sense	6
Lipid-associated macrophages between aggravation and alleviation of metabolic diseases	6
Current status and future perspectives of FGF21 analogues in clinical trials	6
Microtubules in insulin action: what’s on the tube?	6
The time is now for new, lower diabetes diagnostic thresholds	6
Early adversity and insulin: neuroendocrine programming beyond glucocorticoids	6
An epidemiological introduction to human metabolomic investigations	6
What puts the heat on thermogenic fat: metabolism of fuel substrates	6
Long non-coding RNAs in metabolic diseases: from bench to bedside	6
RIPK1 targeting protects against obesity and atherosclerosis	6
Cardiac macrophage metabolism in health and disease	6
Iron effects versus metabolic alterations in hereditary hemochromatosis driven bone loss	6
The emerging potential role of p62 in cancer treatment by regulating metabolism	6
Cellular senescence in pathologic retinal angiogenesis	6
New horizons in specific hormone proteolysis	6
Drosophila as a diet discovery tool for treating amino acid disorders	6
PM2.5-induced adipose tissue dysfunction can trigger metabolic disturbances	6
Maternal metabolism influences neural tube closure	6
Emerging role of T3-binding protein μ-crystallin (CRYM) in health and disease	5
Is high-intensity interval training harmful to health?	5
High-density lipoprotein cholesterol and carcinogenesis	5
Context matters for addressing controversies in FGF21 biology	5
Mechanisms of hepatic fatty acid oxidation and ketogenesis during fasting	5
Lipid metabolism reprogramming in cardiac fibrosis	5
Mesenchymal stromal cells as a tool to unravel the developmental origins of disease	5
Temporal single-cell regeneration studies: the greatest thing since sliced pancreas?	5
IFN-I signaling in cancer: the connection with dysregulated Insulin/IGF axis	5
Mechanisms and pathophysiology of SARS-CoV-2 infection of the adipose tissue	5
Pre-RNA splicing in metabolic homeostasis and liver disease	5
Why equalising HIIT and MICT is important: attention to methodological details	4
Is mitochondrial morphology important for cellular physiology?	4
Osteomorphs as a tool for personalized medicine	4
Metabolic remodeling in cancer and senescence and its therapeutic implications	4
Brain–body communication in metabolic control	4
Common and divergent molecular mechanisms of fasting and ketogenic diets	4
Adipocyte extracellular vesicles: rescuers of cardiac mitochondrial stress	4
Selenium, diabetes, and their intricate sex-specific relationship	4
The gut microbiota: stable bioreactor of variable composition?	4
Finerenone: A Non-steroidal Mineralocorticoid Receptor Blocker for Diabetic Kidney Disease	4
Peripheral nervous system glia in support of metabolic tissue functions	4
Itaconate in host inflammation and defense	4
The impact of chromosomal sex on cardiometabolic health and disease	4
The physiological functions of lymphangiocrine signals	4
Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease	4
Hallmarks of the metabolic secretome	4
The ticking of aging clocks	4
Can sodium-glucose cotransporter 2 inhibitors ‘spin the thread of life’?	4
Jekyll and Hyde: nuclear receptors ignite and extinguish hepatic oxidative milieu	4
PKCα: Prospects in Regulating Insulin Resistance and AD	4
Ion homeostasis in diabetic kidney disease	3
Mitochondrial quality control pathways sense mitochondrial protein import	3
The potential for citrate to reinforce epigenetic therapy by promoting apoptosis	3
Neuroendocrine regulation in stroke	3
Therapeutic opportunities to modulate immune tolerance through the metabolism-chromatin axis	3
mTORC1 syndrome (TorS): unified paradigm for diabetes/metabolic syndrome	3
Carbon metabolism in the regulation of macrophage functions	3
Methylmalonic acid in aging and disease	3
Estradiol and leptin: no engagement without CITED1	3
A seasonal switch hypothesis for the neuroendocrine control of aggression	3
Proteostasis and resilience: on the interphase between individual’s and intracellular stress	3
Dietary methionine restriction in cancer development and antitumor immunity	3
Neuroendocrine gut–brain signaling in obesity	3
Cancer cachexia as a blueprint for treating obesity	3
N6-methyladenosine RNA modification in nonalcoholic fatty liver disease	2
Metabolic homeostasis of tissue macrophages across the lifespan	2
Cellular mechanism of diabetes remission by bariatric surgery	2