Trends in Endocrinology and Metabolism

Papers
(The median citation count of Trends in Endocrinology and Metabolism is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Advisory Board and Contents338
Advisory Board and Contents338
N6-methyladenosine RNA modification in nonalcoholic fatty liver disease276
Cellular mechanism of diabetes remission by bariatric surgery184
How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination160
Advisory Board and Contents157
Metabolic hallmarks of liver regeneration115
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The changing clinical spectrum of endocrine adverse events in cancer immunotherapy106
Unveiling the cancer risk nexus of the steatotic liver97
Cannabinoids and terpenes for diabetes mellitus and its complications: from mechanisms to new therapies93
Maternal metabolism influences neural tube closure92
Neuroendocrine gut–brain signaling in obesity82
Establishing evidence for immune surveillance of β-cell senescence81
Irisin limits amyloid-β buildup in Alzheimer’s disease80
Emerging roles of N-linked glycosylation in brain physiology and disorders80
Subscription and Copyright Information76
Mechanisms of kidney fibrosis and routes towards therapy76
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Advisory Board and Contents74
Healthy choices, healthy futures: promoting healthy nutrition to curb non-communicable diseases74
A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring67
Jekyll and Hyde: nuclear receptors ignite and extinguish hepatic oxidative milieu66
Why cells need iron: a compendium of iron utilisation64
Increased hepatic gluconeogenesis and type 2 diabetes mellitus63
Uridine63
Advisory Board and Contents62
Enhancer binding as a KEysTONE of fasting response61
Metabolic challengers selecting tumor-persistent cells59
Liver-expressed antimicrobial peptide 2 (LEAP2)59
A double-edged sword: risks and benefits of heat for human health58
Drosophila as a diet discovery tool for treating amino acid disorders54
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Is high-intensity interval training harmful to health?51
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GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?48
The landscape of fetus metabolism in maternal hyperglycemia47
‘Rotor free-wheeling’ in impaired F1FO-ATPase induces congenital hypermetabolism47
Beta-hydroxybutyrate47
A multidimensional epidemiological perspective on frailty dynamics and prevention44
Effects of APOE4 on omega-3 brain metabolism across the lifespan44
Olfactory system and energy metabolism: a two-way street44
Sepsis: a failing starvation response43
Mechanomedicine targeting brown adipose tissue for metabolic health43
A metabolic perspective on cuproptosis42
Parathyroid hormone–PTH1R signaling in cardiovascular disease and homeostasis42
Metabolism, homeostasis, and aging42
Current status and future perspectives of FGF21 analogues in clinical trials40
Metabolic remodeling in cancer and senescence and its therapeutic implications40
Advisory Board and Contents39
Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses38
The interplay between endometriosis and obesity37
Can kisspeptin be a new treatment for sexual dysfunction?36
Targeting cholesterol-dependent adrenal steroidogenesis for management of primary aldosteronism35
New tools for bone health assessment in secreting pituitary adenomas35
Gut microbiota and eating behaviour in circadian syndrome34
Lipid-associated macrophages between aggravation and alleviation of metabolic diseases33
Exercise pills for cardiometabolic health cannot mimic the exercise milieu33
Mitochondrial copper in human genetic disorders33
Balancing metabolism and regeneration in liver diseases through HNF4α targeting33
Amino acid transporters as modulators of glucose homeostasis33
Hallmarks of the metabolic secretome33
Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts32
Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic–pituitary–ovarian axis32
Serine signaling governs metabolic homeostasis and health32
Advisory Board and Contents31
Advisory Board and Contents30
B vitamins as adjunct therapies for depressive disorder30
Thyroid wars: the rise of central actions30
A three-layer perspective on miRNA regulation in β cell inflammation30
Shifting metabolism to increase lifespan29
Rewiring of the glymphatic landscape in metabolic disorders29
Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease29
Shared metabolic and stress pathways to neonatal adiposity28
Recompensation in MASLD-related cirrhosis via metabolic bariatric surgery28
Pericytic porters: helping leptin step in28
Advisory Board and Contents28
Exercised breastmilk: a kick-start to prevent childhood obesity?28
Insights from omics research on plant-based diets and cardiometabolic health27
(Poly)phenols as bioactive constituents linked to dietary fibre metabolic fate27
The physiological functions of lymphangiocrine signals26
Why equalising HIIT and MICT is important: attention to methodological details26
More trials for the unhappy hypothyroid patient on thyroxine: a clinician’s perspective26
Mitochondria as sensors of intracellular pathogens26
An epidemiological introduction to human metabolomic investigations25
Gut microbiota controlling radiation-induced enteritis and intestinal regeneration24
Metabolic-immune microenvironment crosstalk mediating ICI resistance in MASH-HCC24
Cardioprotective benefits of metabolic surgery and GLP-1 receptor agonist–based therapies24
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Wildfires and COVID-19: syndemic impact on maternal and child health22
The sphinx helps to answer the riddle of cardiac regeneration22
Creating a picture of brown fat with creatine-CEST21
Metabolic homeostasis of tissue macrophages across the lifespan21
Metabolic consequences of sleep and circadian disruption during pregnancy and postpartum21
Targeting systemic and gut microbial metabolism in ER+ breast cancer20
Road map for personalized exercise medicine in T2DM20
Exploring tryptophan metabolism in cardiometabolic diseases20
Dopamine20
Etherglycerophospholipids and ferroptosis: structure, regulation, and location20
Detection, mechanisms, and therapeutic implications of oncometabolites20
Endoscopic management of obesity and metabolic diseases20
Spatiotemporal coordination between local flux and systemic homeostasis in the small intestine20
Cortisol and cardiometabolic disease: a target for advancing health equity20
Corticosteroid receptors as a model for the Hsp90•immunophilin-based transport machinery19
The time is now for new, lower diabetes diagnostic thresholds19
Apolipoprotein E in lipid metabolism and neurodegenerative disease18
The relationship between CD4+ T cell glycolysis and their functions18
Melatonin18
Assessment and treatment of osteoporosis and fractures in type 2 diabetes18
An orphan to the rescue of obesity and steatotic liver?18
Dietary lipids as regulators of reward processes: multimodal integration matters18
Dietary and pharmacological energy restriction and exercise for healthspan extension18
Gut feelings on short-chain fatty acids to regulate respiratory health18
Systemic and organ-specific anti-inflammatory effects of sodium-glucose cotransporter-2 inhibitors17
Insulin17
SARS-CoV-2 and pancreas: a potential pathological interaction?17
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Pancreatic islet adaptation in pregnancy and postpartum17
Understanding lactate sensing and signalling17
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Early nutritional interventions for chronic low-grade inflammation17
Mitochondrial quality control pathways sense mitochondrial protein import16
GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism16
Microglial metabolic flexibility: emerging roles for lactate16
NAD augmentation as a disease-modifying strategy for neurodegeneration16
SIRT6: therapeutic target for nonalcoholic fatty liver disease16
The impact of epitranscriptomic modifications on liver disease16
Osteomorphs as a tool for personalized medicine15
Glucokinase activity in diabetes: too much of a good thing?15
Regulated cell death in myocardial ischemia–reperfusion injury15
Neural stem cell metabolism revisited: a critical role for mitochondria15
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Decoding microbial volatile signals in host–microbiome crosstalk15
The gut–Snhg9 interplay as a new path to metabolic health14
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First-phase insulin secretion: can its evaluation direct therapeutic approaches?14
Crotonyl-coenzyme A (crotonyl-CoA)14
Pathophysiology of human mitochondrial tRNA metabolism14
Advisory Board and Contents14
Caudamins, a new subclass of protein hormones13
Blood factors as biomarkers in osteoporosis: points from the COVID-19 era13
Proteostasis and resilience: on the interphase between individual’s and intracellular stress13
OPA1 regulation of mitochondrial dynamics in skeletal and cardiac muscle13
Information theory in vertebrate stress physiology13
Long non-coding RNAs in metabolic diseases: from bench to bedside13
Polyamine metabolism in macrophage–adipose tissue function and homeostasis13
Is MASLD lost in translation in mice?13
Integrating cancer medicine into metabolic rhythms13
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Come out and play12
Emerging interactions between mitochondria and NAD+ metabolism in cardiometabolic diseases12
Advisory Board and Contents12
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Vitamin D toxicity related to its physiological and unphysiological supply12
Advancing precision medicine in metabolic dysfunction-associated steatotic liver disease11
Context matters for addressing controversies in FGF21 biology11
Adipocyte extracellular vesicles: rescuers of cardiac mitochondrial stress11
Neural and behavioral plasticity across the female reproductive cycle11
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Mitochondrial dysfunction in lipid processing and gastrointestinal disorders11
Pathophysiology and histopathology of primary aldosteronism11
Advisory Board and Contents11
Genes, environment, and African ancestry in cardiometabolic disorders11
Mitochondrial Venus is more likely to have a lower birthweight11
Unleashing ferroptosis for cancer therapy with warfarin10
Sensing mitochondrial DNA stress in cardiotoxicity10
Bone marrow adipose tissue in metabolic health10
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Apart, together: reflections on the COVID-19 pandemic10
Fructose promotes liver cancer via microbial acetate-induced O-GlcNAcylation10
Chemical chaperones in metabolic fitness beyond protein folding10
Advisory Board and Contents10
Role of metabolic changes of adiposity in cancer10
Revisiting liver metabolism through acetyl-CoA carboxylase inhibition10
Advisory Board and Contents10
Bird evolution by insulin resistance9
Pioneering new frontiers in circadian medicine chronotherapies for cardiovascular health9
Glucagon-like peptide-19
The emerging role of bile acids in white adipose tissue9
Industrialized diets modulate host eating behavior via the microbiome–gut–brain axis9
Food perception induces fast fragmentation of hepatic mitochondria9
Context-specific fatty acid uptake is a finely-tuned multi-level effort9
Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis?8
Advisory Board and Contents8
Eosinophilia in cancer and its regulation by sex hormones8
Neuroendocrine regulation in stroke8
Lineage tracing of pancreatic cells for mechanistic and therapeutic insights8
Growth variations with opposite clinical outcomes and the emerging role of IGF-18
Mesenchymal stromal cells as a tool to unravel the developmental origins of disease8
Autophagy and lysosomal dysfunction in diabetes and its complications8
Advisory Board and Contents8
Mechanisms of lipid metabolism in uterine receptivity and embryo development8
Gonadotropins as pharmacological agents in assisted reproductive technology and polycystic ovary syndrome8
The potential for citrate to reinforce epigenetic therapy by promoting apoptosis8
Targeting ACSLs to modulate ferroptosis and cancer immunity8
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SIRTifying intestinal nucleotide metabolism8
Extracellular vesicle-mediated interorgan communication in metabolic diseases7
Mechanisms and pathophysiology of SARS-CoV-2 infection of the adipose tissue7
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Many or too many progesterone membrane receptors? Clinical implications7
PM2.5-induced adipose tissue dysfunction can trigger metabolic disturbances7
Methylmalonic acid in aging and disease7
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Reconsidering lactate disallowance in pancreatic β cells7
Maternal–fetal mechanisms underlying adaptation to hypoxia during early pregnancy7
Systemic metabolic crosstalk as driver of cancer cachexia7
Ghrelin7
Advisory Board and Contents7
Hallmarks of ovarian aging6
Brain mitochondria in behavior: more than a powerhouse6
Adipose tissue–gut microbiome crosstalk in inflammation and thermogenesis6
Repurposing metabolic drugs as anti-inflammatory agents6
Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency6
Energy as the cornerstone of environmentally driven sex allocation6
Endothelial lipid droplets drive atherosclerosis and arterial hypertension6
Intermittent fasting influences immunity and metabolism6
Neurological aspects of SARS-CoV-2 infection: lipoproteins and exosomes as Trojan horses6
A platform to map the mind–mitochondria connection and the hallmarks of psychobiology: the MiSBIE study6
New prebiotics by ketone donation6
Microglial insulin resistance drives neurodegeneration6
Epigenetic inheritance of PCOS by developmental programming and germline transmission6
Interorganelle phospholipid communication, a house not so divided6
Lipophagy: a new player in CNS disorders6
Dietary fat: a potent microglial influencer5
Advisory Board and Contents5
Contributions of white adipose tissue to energy requirements for female reproduction5
Microbes put drugs in(action)5
The gut microbiota: stable bioreactor of variable composition?5
Advancing health and fostering community involvement in medical research through the Genes & Health study5
Long COVID: pathophysiological factors and abnormalities of coagulation5
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Ceramides in the central control of metabolism5
Advisory Board and Contents5
Irisin, a fascinating field in our times5
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline5
Is cardiovascular disease in PCOS driven by MASLD?5
Advisory Board and Contents5
Connecting precision nutrition with the Food is Medicine approach5
Advisory Board and Contents5
Selenium, diabetes, and their intricate sex-specific relationship5
Digital twins and artificial intelligence in metabolic disease research4
The emerging potential role of p62 in cancer treatment by regulating metabolism4
Regulation of mTOR by phosphatidic acid4
NAD+ (nicotinamide adenine dinucleotide, oxidized form)4
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