Trends in Endocrinology and Metabolism

Papers
(The median citation count of Trends in Endocrinology and Metabolism is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Cellular mechanism of diabetes remission by bariatric surgery413
Maternal metabolism influences neural tube closure363
Emerging roles of N-linked glycosylation in brain physiology and disorders298
The changing clinical spectrum of endocrine adverse events in cancer immunotherapy220
Mechanisms of kidney fibrosis and routes towards therapy170
Contribution of metabolism-independent glucose sensing to metabolic homeostasis167
Irisin limits amyloid-β buildup in Alzheimer’s disease135
How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination119
Advisory Board and Contents112
Advisory Board and Contents105
N6-methyladenosine RNA modification in nonalcoholic fatty liver disease105
Subscription and Copyright Information104
Establishing evidence for immune surveillance of β-cell senescence93
Advisory Board and Contents88
Unveiling the cancer risk nexus of the steatotic liver86
Methionine restriction and mimetics to ameliorate human aging and disease84
Neuroendocrine gut–brain signaling in obesity83
Cannabinoids and terpenes for diabetes mellitus and its complications: from mechanisms to new therapies82
Healthy choices, healthy futures: promoting healthy nutrition to curb non-communicable diseases81
Uridine77
Advisory Board and Contents75
Subscription and Copyright Information74
Why cells need iron: a compendium of iron utilisation73
Dietary medium-chain triacylglycerols in metabolic regulation73
Increased hepatic gluconeogenesis and type 2 diabetes mellitus72
A matter of time: temporal structure and functional relevance of macrophage metabolic rewiring71
Enhancer binding as a KEysTONE of fasting response69
A metabolic perspective on cuproptosis63
A double-edged sword: risks and benefits of heat for human health63
Mechanomedicine targeting brown adipose tissue for metabolic health60
A multidimensional epidemiological perspective on frailty dynamics and prevention59
Is high-intensity interval training harmful to health?58
Effects of APOE4 on omega-3 brain metabolism across the lifespan57
Liver-expressed antimicrobial peptide 2 (LEAP2)56
CD8+ T cell stressors converge on shared metabolic–epigenetic networks55
Parathyroid hormone–PTH1R signaling in cardiovascular disease and homeostasis51
Subscription and Copyright Information50
The landscape of fetus metabolism in maternal hyperglycemia48
Metabolic challengers selecting tumor-persistent cells47
GLP-1 agonists: superior for mind and body in antipsychotic-treated patients?46
Subscription and Copyright Information46
Drosophila as a diet discovery tool for treating amino acid disorders45
Advisory Board and Contents45
Subscription and Copyright Information44
‘Rotor free-wheeling’ in impaired F1FO-ATPase induces congenital hypermetabolism44
Beta-hydroxybutyrate43
Metabolic remodeling in cancer and senescence and its therapeutic implications43
Current status and future perspectives of FGF21 analogues in clinical trials43
Metabolism, homeostasis, and aging42
Olfactory system and energy metabolism: a two-way street42
Sepsis: a failing starvation response40
Can kisspeptin be a new treatment for sexual dysfunction?38
Advisory Board and Contents38
Targeting cholesterol-dependent adrenal steroidogenesis for management of primary aldosteronism38
Exercise pills for cardiometabolic health cannot mimic the exercise milieu37
Balancing metabolism and regeneration in liver diseases through HNF4α targeting37
Serine signaling governs metabolic homeostasis and health36
The interplay between endometriosis and obesity36
Hallmarks of the metabolic secretome36
Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses35
New tools for bone health assessment in secreting pituitary adenomas35
Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic–pituitary–ovarian axis34
Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts33
Amino acid transporters as modulators of glucose homeostasis32
Mitochondrial copper in human genetic disorders32
Lipid-associated macrophages between aggravation and alleviation of metabolic diseases32
Gut microbiota and eating behaviour in circadian syndrome31
Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease31
B vitamins as adjunct therapies for depressive disorder31
Advisory Board and Contents30
Advisory Board and Contents30
A three-layer perspective on miRNA regulation in β cell inflammation30
Shifting metabolism to increase lifespan30
Pericytic porters: helping leptin step in30
Shared metabolic and stress pathways to neonatal adiposity29
Exercised breastmilk: a kick-start to prevent childhood obesity?29
Rewiring of the glymphatic landscape in metabolic disorders29
Cardioprotective benefits of metabolic surgery and GLP-1 receptor agonist–based therapies28
Advisory Board and Contents28
Metabolic-immune microenvironment crosstalk mediating ICI resistance in MASH-HCC28
Mitochondria as sensors of intracellular pathogens27
Insights from omics research on plant-based diets and cardiometabolic health27
The physiological functions of lymphangiocrine signals26
Gut microbiota controlling radiation-induced enteritis and intestinal regeneration26
Recompensation in MASLD-related cirrhosis via metabolic bariatric surgery26
(Poly)phenols as bioactive constituents linked to dietary fibre metabolic fate26
An epidemiological introduction to human metabolomic investigations26
The sphinx helps to answer the riddle of cardiac regeneration25
More trials for the unhappy hypothyroid patient on thyroxine: a clinician’s perspective25
Creating a picture of brown fat with creatine-CEST25
Metabolic consequences of sleep and circadian disruption during pregnancy and postpartum24
Dopamine23
Subscription and Copyright Information23
Cortisol and cardiometabolic disease: a target for advancing health equity22
Road map for personalized exercise medicine in T2DM22
Spatiotemporal coordination between local flux and systemic homeostasis in the small intestine22
Detection, mechanisms, and therapeutic implications of oncometabolites22
Endoscopic management of obesity and metabolic diseases22
Exploring tryptophan metabolism in cardiometabolic diseases22
Wildfires and COVID-19: syndemic impact on maternal and child health22
Metabolic homeostasis of tissue macrophages across the lifespan22
Subscription and Copyright Information21
Subscription and Copyright Information21
Targeting systemic and gut microbial metabolism in ER+ breast cancer21
Etherglycerophospholipids and ferroptosis: structure, regulation, and location21
The time is now for new, lower diabetes diagnostic thresholds20
Melatonin20
An orphan to the rescue of obesity and steatotic liver?20
Apolipoprotein E in lipid metabolism and neurodegenerative disease20
Rethinking ‘normal’: are pubertal milestones and growth charts obsolete?20
Gut feelings on short-chain fatty acids to regulate respiratory health20
The relationship between CD4+ T cell glycolysis and their functions20
Subscription and Copyright Information20
Systemic and organ-specific anti-inflammatory effects of sodium-glucose cotransporter-2 inhibitors20
Assessment and treatment of osteoporosis and fractures in type 2 diabetes20
Dietary and pharmacological energy restriction and exercise for healthspan extension20
Understanding lactate sensing and signalling20
The impact of epitranscriptomic modifications on liver disease19
Subscription and Copyright Information19
Mitochondrial quality control pathways sense mitochondrial protein import19
Decoding microbial volatile signals in host–microbiome crosstalk19
NAD augmentation as a disease-modifying strategy for neurodegeneration18
Early nutritional interventions for chronic low-grade inflammation18
Glucokinase activity in diabetes: too much of a good thing?18
Insulin18
Subscription and Copyright Information17
GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism17
SIRT6: therapeutic target for nonalcoholic fatty liver disease17
SARS-CoV-2 and pancreas: a potential pathological interaction?17
Neural stem cell metabolism revisited: a critical role for mitochondria17
Advisory Board and Contents16
Pancreatic islet adaptation in pregnancy and postpartum16
Is MASLD lost in translation in mice?16
Integrating cancer medicine into metabolic rhythms16
Microglial metabolic flexibility: emerging roles for lactate16
Information theory in vertebrate stress physiology16
Crotonyl-coenzyme A (crotonyl-CoA)16
Regulated cell death in myocardial ischemia–reperfusion injury16
Pathophysiology of human mitochondrial tRNA metabolism16
Caudamins, a new subclass of protein hormones15
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First-phase insulin secretion: can its evaluation direct therapeutic approaches?15
Polyamine metabolism in macrophage–adipose tissue function and homeostasis15
OPA1 regulation of mitochondrial dynamics in skeletal and cardiac muscle15
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Advisory Board and Contents14
The gut–Snhg9 interplay as a new path to metabolic health14
Pathophysiology and histopathology of primary aldosteronism14
Proteostasis and resilience: on the interphase between individual’s and intracellular stress14
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Emerging interactions between mitochondria and NAD+ metabolism in cardiometabolic diseases14
Advancing precision medicine in metabolic dysfunction-associated steatotic liver disease13
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Come out and play13
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Subscription and Copyright Information13
Revisiting liver metabolism through acetyl-CoA carboxylase inhibition12
Vitamin D toxicity related to its physiological and unphysiological supply12
Mitochondrial Venus is more likely to have a lower birthweight12
Chemical chaperones in metabolic fitness beyond protein folding12
Neural and behavioral plasticity across the female reproductive cycle12
Adipocyte extracellular vesicles: rescuers of cardiac mitochondrial stress12
Mitochondrial dysfunction in lipid processing and gastrointestinal disorders12
Sensing mitochondrial DNA stress in cardiotoxicity11
Genes, environment, and African ancestry in cardiometabolic disorders11
Context matters for addressing controversies in FGF21 biology11
Bone marrow adipose tissue in metabolic health11
Industrialized diets modulate host eating behavior via the microbiome–gut–brain axis11
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Role of metabolic changes of adiposity in cancer11
Advisory Board and Contents11
Tanycytes: bloodhounds of the metabolic brain11
Glucagon-like peptide-111
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Fructose promotes liver cancer via microbial acetate-induced O-GlcNAcylation11
Advisory Board and Contents10
Context-specific fatty acid uptake is a finely-tuned multi-level effort10
Food perception induces fast fragmentation of hepatic mitochondria10
Eosinophilia in cancer and its regulation by sex hormones10
Apart, together: reflections on the COVID-19 pandemic10
Advisory Board and Contents10
Pioneering new frontiers in circadian medicine chronotherapies for cardiovascular health10
Unleashing ferroptosis for cancer therapy with warfarin10
Mechanisms of lipid metabolism in uterine receptivity and embryo development9
SIRTifying intestinal nucleotide metabolism9
Mechanisms and pathophysiology of SARS-CoV-2 infection of the adipose tissue9
Autophagy and lysosomal dysfunction in diabetes and its complications9
Targeting ACSLs to modulate ferroptosis and cancer immunity9
Mesenchymal stromal cells as a tool to unravel the developmental origins of disease9
The emerging role of bile acids in white adipose tissue9
MASLD in childhood as a multisystem health challenge beyond the liver9
Neuroendocrine regulation in stroke9
Lineage tracing of pancreatic cells for mechanistic and therapeutic insights9
Mitophagy in the adaptation to pancreatic β cell stress in diabetes8
Gonadotropins as pharmacological agents in assisted reproductive technology and polycystic ovary syndrome8
Growth variations with opposite clinical outcomes and the emerging role of IGF-18
Maternal–fetal mechanisms underlying adaptation to hypoxia during early pregnancy8
Advisory Board and Contents8
Extracellular vesicle-mediated interorgan communication in metabolic diseases8
Systemic metabolic crosstalk as driver of cancer cachexia8
The potential for citrate to reinforce epigenetic therapy by promoting apoptosis8
Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis?8
Methylmalonic acid in aging and disease8
PM2.5-induced adipose tissue dysfunction can trigger metabolic disturbances7
Subscription and Copyright Information7
Endothelial lipid droplets drive atherosclerosis and arterial hypertension7
Microglial insulin resistance drives neurodegeneration7
Epigenetic inheritance of PCOS by developmental programming and germline transmission7
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Is cardiovascular disease in PCOS driven by MASLD?7
Interorganelle phospholipid communication, a house not so divided7
New prebiotics by ketone donation7
Repurposing metabolic drugs as anti-inflammatory agents7
Ghrelin7
Reconsidering lactate disallowance in pancreatic β cells7
Hallmarks of ovarian aging7
Energy as the cornerstone of environmentally driven sex allocation7
Neurological aspects of SARS-CoV-2 infection: lipoproteins and exosomes as Trojan horses6
Connecting precision nutrition with the Food is Medicine approach6
Contributions of white adipose tissue to energy requirements for female reproduction6
Advisory Board and Contents6
Brain mitochondria in behavior: more than a powerhouse6
Many or too many progesterone membrane receptors? Clinical implications6
Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency6
The interplay between organized lymphoid structures and thermogenic adipose tissue6
Selenium, diabetes, and their intricate sex-specific relationship6
Metabolic hallmarks of type 2 diabetes compromise T cell function6
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Long COVID: pathophysiological factors and abnormalities of coagulation6
A platform to map the mind–mitochondria connection and the hallmarks of psychobiology: the MiSBIE study6
Intermittent fasting influences immunity and metabolism6
Ceramides in the central control of metabolism6
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline6
Advisory Board and Contents6
Dietary fat: a potent microglial influencer6
Advisory Board and Contents6
Adipose tissue–gut microbiome crosstalk in inflammation and thermogenesis6
Lipophagy: a new player in CNS disorders6
Advancing health and fostering community involvement in medical research through the Genes & Health study5
Harnessing beta cell regeneration biology for diabetes therapy5
Regulatory networks determining substrate utilization in brown adipocytes5
Maternal nutritional programming shapes the cerebral landscape5
Advisory Board and Contents5
TREM2-expressing macrophages in liver diseases5
Abnormal acinar–β-cell crosstalk in type 2 diabetes5
Cancer cachexia as a blueprint for treating obesity5
Irisin, a fascinating field in our times5
What puts the heat on thermogenic fat: metabolism of fuel substrates5
Equalization of exercise protocols: not if, but how5
The gut microbiota: stable bioreactor of variable composition?5
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