Bioconjugate Chemistry

Papers
(The TQCC of Bioconjugate Chemistry is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Bioorthogonal Chemistry and Its Applications123
The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy120
An Overview of Recent Advances in Biomedical Applications of Click Chemistry96
Nanoparticle-Based Wound Dressing: Recent Progress in the Detection and Therapy of Bacterial Infections86
Synthetic ECM: Bioactive Synthetic Hydrogels for 3D Tissue Engineering66
Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV-266
Reprogramming Tumor Microenvironment with Photothermal Therapy66
Gold Nanoclusters: Imaging, Therapy, and Theranostic Roles in Biomedical Applications62
Copper-Doped Nanoscale Covalent Organic Polymer for Augmented Photo/Chemodynamic Synergistic Therapy and Immunotherapy61
Cancer Photothermal Therapy with ICG-Conjugated Gold Nanoclusters61
MOFs-Derived Fe–N Codoped Carbon Nanoparticles as O2-Evolving Reactor and ROS Generator for CDT/PDT/PTT Synergistic Treatment of Tumors57
3D Bioprinting of Bone Marrow Mesenchymal Stem Cell-Laden Silk Fibroin Double Network Scaffolds for Cartilage Tissue Repair55
Comprehensive Review on Current Interventions, Diagnostics, and Nanotechnology Perspectives against SARS-CoV-255
In Situ One-Step Fluorescence Labeling Strategy of Exosomes via Bioorthogonal Click Chemistry for Real-Time Exosome Tracking In Vitro and In Vivo53
Fluorescent Labeling of Proteins of Interest in Live Cells: Beyond Fluorescent Proteins52
Hyaluronic Acid-Modified Au–Ag Alloy Nanoparticles for Radiation/Nanozyme/Ag+ Multimodal Synergistically Enhanced Cancer Therapy43
Overview of Antibacterial Strategies of Dental Implant Materials for the Prevention of Peri-Implantitis42
The Potential of Various Nanotechnologies for Coronavirus Diagnosis/Treatment Highlighted through a Literature Analysis41
Design Strategies and Medicinal Applications of Metal-Peptidic Bioconjugates41
Recent Advances in Bioorthogonal Click Chemistry for Biomedical Applications39
Metal-Based Nanocatalyst for Combined Cancer Therapeutics39
Radiolabeled Peptides and Antibodies in Medicine39
Heptamethine Cyanine Dye Mediated Drug Delivery: Hype or Hope38
Dendrimers toward Translational Nanotherapeutics: Concise Key Step Analysis38
Supramolecular Encapsulation of Small-Ultrared Fluorescent Proteins in Virus-Like Nanoparticles for Noninvasive In Vivo Imaging Agents37
Design and Application of Receptor-Targeted Fluorescent Probes Based on Small Molecular Fluorescent Dyes37
Site-Specific Bioconjugation Approaches for Enhanced Delivery of Protein Therapeutics and Protein Drug Carriers37
State of the Art in Radiolabeling of Antibodies with Common and Uncommon Radiometals for Preclinical and Clinical Immuno-PET37
Ultrastable PEGylated Calixarene-Coated Gold Nanoparticles with a Tunable Bioconjugation Density for Biosensing Applications36
Quaternary Ammonium Salts: Insights into Synthesis and New Directions in Antibacterial Applications35
Gold/Silver Hybrid Nanoparticles with Enduring Inhibition of Coronavirus Multiplication through Multisite Mechanisms35
Synthetic Multienzyme Complexes Assembled on Virus-like Particles for Cascade Biosynthesis In Cellulo35
Recent Advances in Croconaine Dyes for Bioimaging and Theranostics34
Surface Biomodification of Liposomes and Polymersomes for Efficient Targeted Drug Delivery31
Bioconjugate Supramolecular Pd2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo31
Powerful Chemiluminescence Probe for Rapid Detection of Prostate Specific Antigen Proteolytic Activity: Forensic Identification of Human Semen30
Fluorescent Bioconjugates for Super-Resolution Optical Nanoscopy29
PET/Fluorescence Imaging: An Overview of the Chemical Strategies to Build Dual Imaging Tools29
Engineering Self-Assembling Protein Nanoparticles for Therapeutic Delivery28
Lipopeptides for Vaccine Development28
Mitochondrial Targeting of Probes and Therapeutics to the Powerhouse of the Cell27
Polydopamine Coated PB-MnO2 Nanoparticles as an Oxygen Generator Nanosystem for Imaging-Guided Single-NIR-Laser Triggered Synergistic Photodynamic/Photothermal Therapy27
Site-Specific Antibody Conjugation Strategy to Functionalize Virus-Based Nanoparticles26
New Lipophilic Fluorescent Dyes for Labeling Extracellular Vesicles: Characterization and Monitoring of Cellular Uptake26
Covalent Organic Framework–Titanium Oxide Nanocomposite for Enhanced Sonodynamic Therapy26
Full Color Tunable Aggregation-Induced Emission Luminogen for Bioimaging Based on an Indolizine Molecular Framework26
Bacteriophage Capsid Modification by Genetic and Chemical Methods25
NIR-II Functional Materials for Photoacoustic Theranostics25
Optimized Methods for the Production and Bioconjugation of Site-Specific, Alkyne-Modified Glucagon-like Peptide-1 (GLP-1) Analogs to Azide-Modified Delivery Platforms Using Copper-Catalyzed Alkyne–Azi25
Precision Modification of Native Antibodies25
A Platform for the Generation of Site-Specific Antibody–Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines24
Redox-Responsive Hydrogels for Tunable and “On-Demand” Release of Biomacromolecules24
PEGylated Lipid Nanoparticle Formulations: Immunological Safety and Efficiency Perspective23
Catalytic Nanozyme for Radiation Protection23
Self-Assembling Nanoparticle Vaccines Displaying the Receptor Binding Domain of SARS-CoV-2 Elicit Robust Protective Immune Responses in Rhesus Monkeys23
Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody–Drug Conjugates23
Gold Nanoclusters-Decorated Zeolitic Imidazolate Frameworks with Reactive Oxygen Species Generation for Photoenhanced Antibacterial Study23
Shortwave-Infrared Fluorescent Molecular Imaging Probes Based on π-Conjugation Extended Indocyanine Green22
Spherical Nucleic Acid Mediated Functionalization of Polydopamine-Coated Nanoparticles for Selective DNA Extraction and Detection22
The Protein Corona Does Not Influence Receptor-Mediated Targeting of Virus-like Particles22
Artificial Molecular Chaperone Systems for Proteins, Nucleic Acids, and Synthetic Molecules22
Penetrating the Blood-Brain Barrier with New Peptide–Porphyrin Conjugates Having anti-HIV Activity22
Recent Breakthrough in 68Ga-Radiopharmaceuticals Cold Kits for Convenient PET Radiopharmacy22
Platensimycin-Encapsulated Poly(lactic-co-glycolic acid) and Poly(amidoamine) Dendrimers Nanoparticles with Enhanced Anti-Staphylococcal Activity in Vivo22
New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice22
Molecular Imaging-Guided Sonodynamic Therapy21
The Stabilizing Mechanism of Immobilized Metagenomic Xylanases on Bio-Based Hydrogels to Improve Utilization Performance: Computational and Functional Perspectives21
Fabrication of Patterned Hydrogel Interfaces: Exploiting the Maleimide Group as a Dual Purpose Handle for Cross-Linking and Bioconjugation21
Affinity-Based Methods for Site-Specific Conjugation of Antibodies21
In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry21
High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody–Gold Nanoparticle Conjugates21
Electrostatic Conjugation of Nanoparticle Surfaces with Functional Peptide Motifs21
Cysteine-Based Coupling: Challenges and Solutions21
Optimizing an Antioxidant TEMPO Copolymer for Reactive Oxygen Species Scavenging and Anti-Inflammatory Effects in Vivo20
PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling20
Supramolecular “Click Chemistry” for Targeting in the Body20
Anchor, Spacer, and Ligand-Modified Engineered Exosomes for Trackable Targeted Therapy20
Chemiluminescence Detection of Hydrogen Sulfide Release by β-Lactamase-Catalyzed β-Lactam Biodegradation: Unprecedented Pathway for Monitoring β-Lactam Antibiotic Bacterial Resistance20
Sortase-Mediated Quantifiable Enzyme Immobilization on Magnetic Nanoparticles20
Peptide-Chitosan Engineered Scaffolds for Biomedical Applications20
Chemo-Mechanical Modulation of Cell Motions Using DNA Nanosprings20
Protein Delivery: If Your GFP (or Other Small Protein) Is in the Cytosol, It Will Also Be in the Nucleus20
Facile Synthesis of Amphiphilic Fluorescent Phosphorus Dendron-Based Micelles as Antiproliferative Agents: First Investigations19
Homologous Structural, Chemical, and Biological Behavior of Sc and Lu Complexes of the Picaga Bifunctional Chelator: Toward Development of Matched Theranostic Pairs for Radiopharmaceutical Application19
PEGylated Nanoscale Metal–Organic Frameworks for Targeted Cancer Imaging and Drug Delivery19
Compact, “Clickable” Quantum Dots Photoligated with Multifunctional Zwitterionic Polymers for Immunofluorescence and In Vivo Imaging19
Pioneering Iodine-125-Labeled Nanoscale Covalent Organic Frameworks for Brachytherapy18
Developing PEGylated Reversed D-Peptide as a Novel HER2-Targeted SPECT Imaging Probe for Breast Cancer Detection18
Enzyme-Agnostic Lysosomal Screen Identifies New Legumain-Cleavable ADC Linkers18
Squaric Acid-Based Radiopharmaceuticals for Tumor Imaging and Therapy18
Efficient Sortase-Mediated Ligation Using a Common C-Terminal Fusion Tag18
Bivalent Conjugate Vaccine Induces Dual Immunogenic Response That Attenuates Heroin and Fentanyl Effects in Mice18
Multifunctional Nanozyme Hydrogel with Mucosal Healing Activity for Single-Dose Ulcerative Colitis Therapy18
Dual Site-Specific Chemoenzymatic Antibody Fragment Conjugation Using CRISPR-Based Hybridoma Engineering18
One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody–Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling18
Triaging of DNA-Encoded Library Selection Results by High-Throughput Resynthesis of DNA–Conjugate and Affinity Selection Mass Spectrometry17
Nongenetic Bioconjugation Strategies for Modifying Cell Membranes and Membrane Proteins: A Review17
Reactive Oxygen Species-Responsive Liposomes via Boronate-Caged Phosphatidylethanolamine17
Strategies to Control or Mimic Growth Factor Activity for Bone, Cartilage, and Osteochondral Tissue Engineering17
An Apoferritin–Hemagglutinin Conjugate Vaccine with Encapsulated Nucleoprotein Antigen Peptide from Influenza Virus Confers Enhanced Cross Protection17
Reduction-Sensitive Dextran–Paclitaxel Polymer–Drug Conjugate: Synthesis, Self-Assembly into Nanoparticles, and In Vitro Anticancer Efficacy16
Peptide-Functionalized Quantum Dots for Rapid Label-Free Sensing of 2,4,6-Trinitrotoluene16
Investigational Therapies for Primary Hyperoxaluria16
Doxorubicin-Loaded Walnut-Shaped Polydopamine Nanomotor for Photothermal-Chemotherapy of Cancer16
Developing GLP-1 Conjugated Self-Assembling Nanofibers Using Copper-Catalyzed Alkyne–Azide Cycloaddition and Evaluation of Their Biological Activity16
Highly Photoluminescent Nitrogen- and Zinc-Doped Carbon Dots for Efficient Delivery of CRISPR/Cas9 and mRNA16
The Protein Corona Conundrum: Exploring the Advantages and Drawbacks of its Presence around Amphiphilic Nanoparticles16
H2BZmacropa-NCS: A Bifunctional Chelator for Actinium-225 Targeted Alpha Therapy16
Silk Sericin-Polylactide Protein–Polymer Conjugates as Biodegradable Amphiphilic Materials and Their Application in Drug Release Systems16
Recent Progress in Bile Acid-Based Antimicrobials16
Multifunctional Transferrin Encapsulated GdF3 Nanoparticles for Sentinel Lymph Node and Tumor Imaging16
Supramolecular β-Sheet Forming Peptide Conjugated with Near-Infrared Chromophore for Selective Targeting, Imaging, and Dysfunction of Mitochondria16
Design, Synthesis, and Evaluation of Trivalent PROTACs Having a Functionalization Site with Controlled Orientation16
Cyclotriphosphazene-Based “Butterfly” Fluorescence Probe for Lysosome Targeting16
Nanotargeting of Resistant Infections with a Special Emphasis on the Biofilm Landscape16
Protein Conjugation by Electrophilic Alkynylation Using 5-(Alkynyl)dibenzothiophenium Triflates15
Internal Oligoguanidinium Transporter: Mercury-Free Scalable Synthesis, Improvement of Cellular Localization, Endosomal Escape, Mitochondrial Localization, and Conjugation with Antisense Morpholino fo15
[68Ga]Ga-THP-Pam: A Bisphosphonate PET Tracer with Facile Radiolabeling and Broad Calcium Mineral Affinity15
Site-Specific Conjugation Strategy for Dual Antibody–Drug Conjugates Using Aerobic Formylglycine-Generating Enzymes15
Two-Photon and Multicolor Fluorogenic Bioorthogonal Probes Based on Tetrazine-Conjugated Naphthalene Fluorophores15
Ongoing Clinical Trials of Nonviral siRNA Therapeutics15
Exo-Enzymatic Cell-Surface Glycan Labeling for Capturing Glycan–Protein Interactions through Photo-Cross-Linking15
Combinatorial Library of Cyclic Benzylidene Acetal-Containing pH-Responsive Lipidoid Nanoparticles for Intracellular mRNA Delivery15
Coelenterazine Analogue with Human Serum Albumin-Specific Bioluminescence15
Noncovalent Indocyanine Green Conjugate of C-Phycocyanin: Preparation and Tumor-Associated Macrophages-Targeted Photothermal Therapeutics15
The Influence of a Polyethylene Glycol Linker on the Metabolism and Pharmacokinetics of a 89Zr-Radiolabeled Antibody15
NIR Fluorescent Imaging and Photodynamic Therapy with a Novel Theranostic Phospholipid Probe for Triple-Negative Breast Cancer Cells14
Cyclic Anhydrides as Powerful Tools for Bioconjugation and Smart Delivery14
Condensation of DNA-Conjugated Imines with Homophthalic Anhydride for the Synthesis of Isoquinolones on DNA14
Label-Free, Multiplex Glycan Microarray Biosensor for Influenza Virus Detection14
Pam3CSK4-CDGSF Augments Antitumor Immunotherapy by Synergistically Activating TLR1/2 and STING14
Ultrasound-Augmented Phase Transition Nanobubbles for Targeted Treatment of Paclitaxel-Resistant Cancer14
Dual Blood–Brain Barrier–Glioma Targeting Peptide–Poly(levodopamine) Hybrid Nanoplatforms as Potential Near Infrared Phototheranostic Agents in Glioblastoma14
Cyclodextrin/Adamantane-Mediated Targeting of Inoculated Bacteria in Mice14
DiPODS: A Reagent for Site-Specific Bioconjugation via the Irreversible Rebridging of Disulfide Linkages14
Chemoselective Methionine Bioconjugation: Site-Selective Fluorine-18 Labeling of Proteins and Peptides14
Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells14
Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes14
Gold Nanoparticles as Carriers for Functional RNA Nanostructures13
Tailored Linker Chemistries for the Efficient and Selective Activation of ADCs with KSPi Payloads13
Innovative Bioconjugation Technology for Antibody–Drug Conjugates: Proof of Concept in a CD30-Positive Lymphoma Mouse Model13
Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold13
Zwitterionic Polymer Conjugated Glucagon-like Peptide-1 for Prolonged Glycemic Control13
Acoustically Detonated Microbubbles Coupled with Low Frequency Insonation: Multiparameter Evaluation of Low Energy Mechanical Ablation13
Stable and Highly Efficient Antibody–Nanoparticles Conjugation13
Expanding the Scope of Ugi Multicomponent Bioconjugation to Produce Pneumococcal Multivalent Glycoconjugates as Vaccine Candidates13
Designed Streptococcus pyogenes Sortase A Accepts Branched Amines as Nucleophiles in Sortagging13
Ratiometric Fluorescent Biosensor Based on Self-Assembled Fluorescent Gold Nanoparticles and Duplex-Specific Nuclease-Assisted Signal Amplification for Sensitive Detection of Exosomal miRNA13
ImmunoPET of CD146 in Orthotopic and Metastatic Breast Cancer Models13
Resveratrol Carbon Dots Disrupt Mitochondrial Function in Cancer Cells13
Molecular Dynamics-Guided Design of a Functional Protein–ATRP Conjugate That Eliminates Protein–Protein Interactions13
Theranostic Activity of Nitric Oxide-Releasing Carbon Quantum Dots13
Targeted In Vivo Loading of Red Blood Cells Markedly Prolongs Nanocarrier Circulation13
Targeted Delivery of Cabazitaxel Using Cyclic Cell-Penetrating Peptide and Biomarkers of Extracellular Matrix for Prostate and Breast Cancer Therapy13
3D-Printing Biodegradable PU/PAAM/Gel Hydrogel Scaffold with High Flexibility and Self-Adaptibility to Irregular Defects for Nonload-Bearing Bone Regeneration13
Hypoxia-Activated Prodrug Enabling Synchronous Chemotherapy and HIF-1α Downregulation for Tumor Treatment13
Genetic Code Expansion Enables Site-Specific PEGylation of a Human Growth Hormone Receptor Antagonist through Click Chemistry13
Dendrimer-Based Nanogels for Cancer Nanomedicine Applications13
Tailored Bioorthogonal and Bioconjugate Chemistry: A Source of Inspiration for Developing Kinetic Target-Guided Synthesis Strategies13
Supramolecular Dipeptide-Based Near-Infrared Fluorescent Nanotubes for Cellular Mitochondria Targeted Imaging and Early Apoptosis13
Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model13
A Novel NAMPT Inhibitor-Based Antibody–Drug Conjugate Payload Class for Cancer Therapy13
AIE-Based Dynamic in Situ Nanoscale Visualization of Amyloid Fibrillation from Hen Egg White Lysozyme13
Identification of a DNA Aptamer That Binds to Human Monocytes and Macrophages13
Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation12
Benzylguanidine and Galactose Double-Conjugated Chitosan Nanoparticles with Reduction Responsiveness for Targeted Delivery of Doxorubicin to CXCR 4 Positive Tumors12
Efficient Labeling of Native Human IgG by Proximity-Based Sortase-Mediated Isopeptide Ligation12
Folic Acid-Functionalized Nanomedicine: Folic Acid Conjugated Copolymer and Folate Receptor Interactions Disrupt Receptor Functionality Resulting in Dual Therapeutic Anti-Cancer Potential in Breast an12
Silicon-Containing Neurotensin Analogues as Radiopharmaceuticals for NTS1-Positive Tumors Imaging12
Recent Advances in Nanomaterials with Inherent Optical and Magnetic Properties for Bioimaging and Imaging-Guided Nucleic Acid Therapy12
Combining Doxorubicin-Conjugated Polymeric Nanoparticles and 5-Aminolevulinic Acid for Enhancing Radiotherapy against Lung Cancer12
Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine12
Expanding the Scope of Antibody Rebridging with New Pyridazinedione–TCO Constructs12
Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma12
Impact of Ligand Size and Conjugation Chemistry on the Performance of Universal Chimeric Antigen Receptor T-Cells for Tumor Killing12
Recent Progress of Surface Modified Nanomaterials for Scavenging Reactive Oxygen Species in Organism12
NIR II Luminescence Imaging for Sentinel Lymph Node and Enhanced Chemo-/Photothermal Therapy for Breast Cancer12
A Simple and Efficient Method to Generate Dual Site-Specific Conjugation ADCs with Cysteine Residue and an Unnatural Amino Acid12
Designing Functional Bionanoconstructs for Effective In Vivo Targeting12
Solid-Phase Assembly of Multienzyme Systems into Artificial Cellulosomes12
One-Pot Synthesis of Defined-Length ssDNA for Multiscaffold DNA Origami12
A NIR Aggregation-Induced Emission Fluoroamphiphile as Visually Trackable and Serum-Tolerant Nonviral Gene Carrier12
Synthesis and Shaping of Core–Shell Tecto Dendrimers for Biomedical Applications12
Enabling Indium Channels for Mass Cytometry by Using Reinforced Cyclam-Based Chelating Polylysine12
Site-Specific and Trigger-Activated Modification of Proteins by Means of Catalytic Hemin/G-quadruplex DNAzyme Nanostructures12
EGFR Ligand Clustering on E2 Bionanoparticles for Targeted Delivery of Chemotherapeutics to Breast Cancer Cells11
DNA-Compatible Synthesis of α,β-Epoxyketones for DNA-Encoded Chemical Libraries11
HaloTag Forms an Intramolecular Disulfide11
Synthesis and Evaluation of New Trivalent Ligands for Hepatocyte Targeting via the Asialoglycoprotein Receptor11
Multifunctional Neomycin-Triazine-Based Cationic Lipids for Gene Delivery with Antibacterial Properties11
Nanopaper Biosensors at Point of Care11
Renal Handling of 99mTc-Labeled Antibody Fab Fragments with a Linkage Cleavable by Enzymes on Brush Border Membrane11
Lighting Up the Thrombin-Binding Aptamer G-Quadruplex with an Internal Cyanine-Indole-Quinolinium Nucleobase Surrogate. Direct Fluorescent Intensity Readout for Thrombin Binding without Topology Switc11
Dual Site-Selective Presentation of Functional Handles on Protein-Engineered Cowpea Chlorotic Mottle Virus-Like Particles11
“Clickable” Polymer Brush Interfaces: Tailoring Monovalent to Multivalent Ligand Display for Protein Immobilization and Sensing11
Complement Inhibitors Block Complement C3 Opsonization and Improve Targeting Selectivity of Nanoparticles in Blood11
A Plug-and-Play Platform for the Formation of Trifunctional Cysteine Bioconjugates that also Offers Control over Thiol Cleavability11
Effects of Glycosylation and d-Amino Acid Substitution on the Antitumor and Antibacterial Activities of Bee Venom Peptide HYL11
The Role of Ultrasound in Modulating Interstitial Fluid Pressure in Solid Tumors for Improved Drug Delivery11
Conjugated Protein Domains as Engineered Scaffold Proteins11
Generation and Biological Evaluation of Fc Antigen Binding Fragment-Drug Conjugates as a Novel Antibody-Based Format for Targeted Drug Delivery11
RGD-Modified Titanium as an Improved Osteoinductive Biomaterial for Use in Dental and Orthopedic Implants11
Chemo-Enzymatic PEGylation/POxylation of Murine Interleukin-411
Development of Red-Emissive Carbon Dots for Bioimaging through a Building Block Approach: Fundamental and Applied Studies11
Fluorescent Peptide Dendrimers for siRNA Transfection: Tracking pH Responsive Aggregation, siRNA Binding, and Cell Penetration11
Large, Anionic Liposomes Enable Targeted Intraperitoneal Delivery of a TLR 7/8 Agonist To Repolarize Ovarian Tumors’ Microenvironment11
Biotinylated Streptavidin Surface Coating Improves the Efficacy of a PLGA Microparticle-Based Cancer Vaccine11
Nucleic Acid Conformation Influences Postsynthetic Suzuki–Miyaura Labeling of Oligonucleotides11
Nanolipoprotein Particles as a Delivery Platform for Fab Based Therapeutics11
Development of [18F]AmBF3 Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [18F]AmBF3-PEG7-Tyr3-Octr11
Development of a Squaraine-Based Molecular Probe for Dual-Modal in Vivo Fluorescence and Photoacoustic Imaging11
Non-Genetic Generation of Antibody Conjugates Based on Chemoenzymatic Tyrosine Click Chemistry10
RXH-Reactive 18F-Vinyl Sulfones as Versatile Agents for PET Probe Construction10
IgG-Binding Nanobody Capable of Prolonging Nanobody-Based Radiotracer Plasma Half-Life and Enhancing the Efficacy of Tumor-Targeted Radionuclide Therapy10
Enhancing the Carboxylation Efficiency of Silk Fibroin through the Disruption of Noncovalent Interactions10
Structural Investigations, Cellular Imaging, and Radiolabeling of Neutral, Polycationic, and Polyanionic Functional Metalloporphyrin Conjugates10
Epigenetic Platinum Complexes Breaking the “Eat Me/Don’t Eat Me” Balance for Enhanced Cancer Chemoimmunotherapy10
Biocompatible and Rapid Cyclization of Peptides with 2,4-Difluoro-6-hydroxy-1,3,5-benzenetricarbonitrile for the Development of Cyclic Peptide Libraries10
Directly Quantifiable Biotinylation Using a Water-Soluble Isatoic Anhydride Platform10
Amino BODIPY-Based Blue Fluorescent Probes for Aldehyde Dehydrogenase 1-Expressing Cells10
Optimization of Enzymolysis Clearance Strategy To Enhance Renal Clearance of Radioligands10
Cyclic Thiosulfinates as a Novel Class of Disulfide Cleavable Cross-Linkers for Rapid Hydrogel Synthesis10
Engineering PEGylated Polyester Nanoparticles to Reduce Complement-Mediated Infusion Reaction10
Isotope-Coded Maleimide Affinity Tags for Proteomics Applications10
Precise Installation of Diazo-Tagged Side-Chains on Proteins to Enable In Vitro and In-Cell Site-Specific Labeling10
Ultrasonic-Assisted Solid-Phase Peptide Synthesis of DOTA-TATE and DOTA-linker-TATE Derivatives as a Simple and Low-Cost Method for the Facile Synthesis of Chelator–Peptide Conjugates10
Temporal Control of Efficient In Vivo Bioconjugation Using a Genetically Encoded Tetrazine-Mediated Inverse-Electron-Demand Diels–Alder Reaction10
Site-Specific, Platform-Based Conjugation Strategy for the Synthesis of Dual-Labeled Immunoconjugates for Bimodal PET/NIRF Imaging of HER2-Positive Tumors10
An Integrin Alpha 6-Targeted Radiotracer with Improved Receptor Binding Affinity and Tumor Uptake10
Flavin-Conjugated Nanobombs: Key Structural Requirements Governing Their Self-Assemblies’ Morphologies10
FRET-Based Method for Direct, Real-Time Measurement of DNA Methyltransferase Activity10
An Integrated Tumor Microenvironment Responsive Polymeric Micelle for Smart Drug Delivery and Effective Drug Release10
Redox-Responsive Nanocapsules for the Spatiotemporal Release of Miltefosine in Lysosome: Protection against Leishmania10
Blood-Brain Barrier Penetrating Luminescent Conjugates Based on Cyclometalated Platinum(II) Complexes10
Bioinspired Fabrication of Calcium-Doped TiP Coating with Nanofibrous Microstructure to Accelerate Osseointegration10
Thiol-Reactive Clickable Cryogels: Importance of Macroporosity and Linkers on Biomolecular Immobilization9
Cucurbituril–Ferrocene: Host–Guest Based Pretargeted Positron Emission Tomography in a Xenograft Model9
Recent Advances in Bioorthogonal Click Chemistry for Enhanced PET and SPECT Radiochemistry9
Synthesis and Evaluation of Ubiquitin–Dioxetane Conjugate as a Chemiluminescent Probe for Monitoring Deubiquitinase Activity9
Design of Neuraminidase-Targeted Imaging and Therapeutic Agents for the Diagnosis and Treatment of Influenza Virus Infections9
Potentiating the Membrane Interaction of an Attenuated Cationic Amphiphilic Lytic Peptide for Intracellular Protein Delivery by Anchoring with Pyrene Moiety9
Fast and Selective Reaction of 2-Benzylacrylaldehyde with 1,2-Aminothiol for Stable N-Terminal Cysteine Modification and Peptide Cyclization9
Synthesis and Evaluation of Three Azide-Modified Disaccharide Oxazolines as Enzyme Substrates for Single-Step Fc Glycan-Mediated Antibody-Drug Conjugation9
Rapid, High-Yielding Solid-Phase Synthesis of Cathepsin-B Cleavable Linkers for Targeted Cancer Therapeutics9
Ratiometric Fluorescence Monitoring of Antibody-Guided Drug Delivery to Cancer Cells9
DNA Compatible Oxidization and Amidation of Terminal Alkynes9
Large-Scale 3D Optical Mapping and Quantitative Analysis of Nanoparticle Distribution in Tumor Vascular Microenvironment9
Simultaneous Targeting of Two Master Regulators of Apoptosis with Dual-Action PNA– and DNA–Peptide Conjugates9
An Artificial Amphiphilic Peptide Promotes Endocytic Uptake by Inducing Membrane Curvature9
Kinetics and Optimization of the Lysine–Isopeptide Bond Forming Sortase Enzyme from Corynebacterium diphtheriae9
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