Bioconjugate Chemistry

Article	Citations
Bioorthogonal Chemistry and Its Applications	171
An Overview of Recent Advances in Biomedical Applications of Click Chemistry	122
Gold Nanoclusters: Imaging, Therapy, and Theranostic Roles in Biomedical Applications	82
Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV-2	73
MOFs-Derived Fe–N Codoped Carbon Nanoparticles as O2-Evolving Reactor and ROS Generator for CDT/PDT/PTT Synergistic Treatment of Tumors	59
Quaternary Ammonium Salts: Insights into Synthesis and New Directions in Antibacterial Applications	55
PEGylated Lipid Nanoparticle Formulations: Immunological Safety and Efficiency Perspective	53
Overview of Antibacterial Strategies of Dental Implant Materials for the Prevention of Peri-Implantitis	49
Radiolabeled Peptides and Antibodies in Medicine	47
Recent Advances in Bioorthogonal Click Chemistry for Biomedical Applications	47
State of the Art in Radiolabeling of Antibodies with Common and Uncommon Radiometals for Preclinical and Clinical Immuno-PET	46
Design and Application of Receptor-Targeted Fluorescent Probes Based on Small Molecular Fluorescent Dyes	45
Engineering Self-Assembling Protein Nanoparticles for Therapeutic Delivery	41
Ultrastable PEGylated Calixarene-Coated Gold Nanoparticles with a Tunable Bioconjugation Density for Biosensing Applications	41
Surface Biomodification of Liposomes and Polymersomes for Efficient Targeted Drug Delivery	38
Bioconjugate Supramolecular Pd2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo	37
Lipopeptides for Vaccine Development	33
New Lipophilic Fluorescent Dyes for Labeling Extracellular Vesicles: Characterization and Monitoring of Cellular Uptake	32
Redox-Responsive Hydrogels for Tunable and “On-Demand” Release of Biomacromolecules	32
PET/Fluorescence Imaging: An Overview of the Chemical Strategies to Build Dual Imaging Tools	32
NIR-II Functional Materials for Photoacoustic Theranostics	31
Bacteriophage Capsid Modification by Genetic and Chemical Methods	31
Affinity-Based Methods for Site-Specific Conjugation of Antibodies	31
Covalent Organic Framework–Titanium Oxide Nanocomposite for Enhanced Sonodynamic Therapy	31
Mitochondrial Targeting of Probes and Therapeutics to the Powerhouse of the Cell	30

Molecular Imaging-Guided Sonodynamic Therapy	29
Precision Modification of Native Antibodies	29
Ongoing Clinical Trials of Nonviral siRNA Therapeutics	28
Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody–Drug Conjugates	27
Self-Assembling Nanoparticle Vaccines Displaying the Receptor Binding Domain of SARS-CoV-2 Elicit Robust Protective Immune Responses in Rhesus Monkeys	27
Cysteine-Based Coupling: Challenges and Solutions	27
Catalytic Nanozyme for Radiation Protection	25
Doxorubicin-Loaded Walnut-Shaped Polydopamine Nanomotor for Photothermal-Chemotherapy of Cancer	25
Recent Breakthrough in 68Ga-Radiopharmaceuticals Cold Kits for Convenient PET Radiopharmacy	24
Strategies to Control or Mimic Growth Factor Activity for Bone, Cartilage, and Osteochondral Tissue Engineering	24
Shortwave-Infrared Fluorescent Molecular Imaging Probes Based on π-Conjugation Extended Indocyanine Green	24
Spherical Nucleic Acid Mediated Functionalization of Polydopamine-Coated Nanoparticles for Selective DNA Extraction and Detection	24
Peptide-Chitosan Engineered Scaffolds for Biomedical Applications	24
Multifunctional Nanozyme Hydrogel with Mucosal Healing Activity for Single-Dose Ulcerative Colitis Therapy	23
Supramolecular “Click Chemistry” for Targeting in the Body	23
Chemo-Mechanical Modulation of Cell Motions Using DNA Nanosprings	23
Optimizing an Antioxidant TEMPO Copolymer for Reactive Oxygen Species Scavenging and Anti-Inflammatory Effects in Vivo	23
High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody–Gold Nanoparticle Conjugates	23
PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling	23
Penetrating the Blood-Brain Barrier with New Peptide–Porphyrin Conjugates Having anti-HIV Activity	23
Chemiluminescence Detection of Hydrogen Sulfide Release by β-Lactamase-Catalyzed β-Lactam Biodegradation: Unprecedented Pathway for Monitoring β-Lactam Antibiotic Bacterial Resistance	22
The Evolving Landscape of Antibody–Drug Conjugates: In Depth Analysis of Recent Research Progress	22
PEGylated Nanoscale Metal–Organic Frameworks for Targeted Cancer Imaging and Drug Delivery	22
In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry	22
Protein Delivery: If Your GFP (or Other Small Protein) Is in the Cytosol, It Will Also Be in the Nucleus	22
Enzyme-Agnostic Lysosomal Screen Identifies New Legumain-Cleavable ADC Linkers	21
Triaging of DNA-Encoded Library Selection Results by High-Throughput Resynthesis of DNA–Conjugate and Affinity Selection Mass Spectrometry	21
Developing GLP-1 Conjugated Self-Assembling Nanofibers Using Copper-Catalyzed Alkyne–Azide Cycloaddition and Evaluation of Their Biological Activity	21
Squaric Acid-Based Radiopharmaceuticals for Tumor Imaging and Therapy	20
Pioneering Iodine-125-Labeled Nanoscale Covalent Organic Frameworks for Brachytherapy	20
Dual Site-Specific Chemoenzymatic Antibody Fragment Conjugation Using CRISPR-Based Hybridoma Engineering	20
Cyclotriphosphazene-Based “Butterfly” Fluorescence Probe for Lysosome Targeting	20
The Influence of a Polyethylene Glycol Linker on the Metabolism and Pharmacokinetics of a 89Zr-Radiolabeled Antibody	20
Homologous Structural, Chemical, and Biological Behavior of Sc and Lu Complexes of the Picaga Bifunctional Chelator: Toward Development of Matched Theranostic Pairs for Radiopharmaceutical Application	19
Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes	19
H2BZmacropa-NCS: A Bifunctional Chelator for Actinium-225 Targeted Alpha Therapy	19
Reduction-Sensitive Dextran–Paclitaxel Polymer–Drug Conjugate: Synthesis, Self-Assembly into Nanoparticles, and In Vitro Anticancer Efficacy	19
Facile Synthesis of Amphiphilic Fluorescent Phosphorus Dendron-Based Micelles as Antiproliferative Agents: First Investigations	19
Cyclic Anhydrides as Powerful Tools for Bioconjugation and Smart Delivery	19
Highly Photoluminescent Nitrogen- and Zinc-Doped Carbon Dots for Efficient Delivery of CRISPR/Cas9 and mRNA	19
Label-Free, Multiplex Glycan Microarray Biosensor for Influenza Virus Detection	19
Recent Progress in Bile Acid-Based Antimicrobials	19
Large, Anionic Liposomes Enable Targeted Intraperitoneal Delivery of a TLR 7/8 Agonist To Repolarize Ovarian Tumors’ Microenvironment	18
Tailored Bioorthogonal and Bioconjugate Chemistry: A Source of Inspiration for Developing Kinetic Target-Guided Synthesis Strategies	18
One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody–Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling	18
The Protein Corona Conundrum: Exploring the Advantages and Drawbacks of its Presence around Amphiphilic Nanoparticles	18
Dendrimer-Based Nanogels for Cancer Nanomedicine Applications	18
Nongenetic Bioconjugation Strategies for Modifying Cell Membranes and Membrane Proteins: A Review	18
Multifunctional Transferrin Encapsulated GdF3 Nanoparticles for Sentinel Lymph Node and Tumor Imaging	18
Bivalent Conjugate Vaccine Induces Dual Immunogenic Response That Attenuates Heroin and Fentanyl Effects in Mice	18

Nanotargeting of Resistant Infections with a Special Emphasis on the Biofilm Landscape	18
Exo-Enzymatic Cell-Surface Glycan Labeling for Capturing Glycan–Protein Interactions through Photo-Cross-Linking	18
One-Pot Synthesis of Defined-Length ssDNA for Multiscaffold DNA Origami	18
Design, Synthesis, and Evaluation of Trivalent PROTACs Having a Functionalization Site with Controlled Orientation	17
Supramolecular Dipeptide-Based Near-Infrared Fluorescent Nanotubes for Cellular Mitochondria Targeted Imaging and Early Apoptosis	17
Site-Specific Conjugation Strategy for Dual Antibody–Drug Conjugates Using Aerobic Formylglycine-Generating Enzymes	17
Designing Functional Bionanoconstructs for Effective In Vivo Targeting	17
Synthesis and Shaping of Core–Shell Tecto Dendrimers for Biomedical Applications	17
A NIR Aggregation-Induced Emission Fluoroamphiphile as Visually Trackable and Serum-Tolerant Nonviral Gene Carrier	17
NIR Fluorescent Imaging and Photodynamic Therapy with a Novel Theranostic Phospholipid Probe for Triple-Negative Breast Cancer Cells	17
Molecular Dynamics-Guided Design of a Functional Protein–ATRP Conjugate That Eliminates Protein–Protein Interactions	17
3D-Printing Biodegradable PU/PAAM/Gel Hydrogel Scaffold with High Flexibility and Self-Adaptibility to Irregular Defects for Nonload-Bearing Bone Regeneration	17
“Clickable” Polymer Brush Interfaces: Tailoring Monovalent to Multivalent Ligand Display for Protein Immobilization and Sensing	17
Coelenterazine Analogue with Human Serum Albumin-Specific Bioluminescence	17
Generation and Biological Evaluation of Fc Antigen Binding Fragment-Drug Conjugates as a Novel Antibody-Based Format for Targeted Drug Delivery	17
Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma	17
Ratiometric Fluorescent Biosensor Based on Self-Assembled Fluorescent Gold Nanoparticles and Duplex-Specific Nuclease-Assisted Signal Amplification for Sensitive Detection of Exosomal miRNA	17
Click Chemistry and Radiochemistry: An Update	16
Protein Conjugation by Electrophilic Alkynylation Using 5-(Alkynyl)dibenzothiophenium Triflates	16
Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold	16
Dual Blood–Brain Barrier–Glioma Targeting Peptide–Poly(levodopamine) Hybrid Nanoplatforms as Potential Near Infrared Phototheranostic Agents in Glioblastoma	16
Recent Advances in Bioorthogonal Click Chemistry for Enhanced PET and SPECT Radiochemistry	16
Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation	16
Synergistic Experimental and Computational Investigation of the Bioorthogonal Reactivity of Substituted Aryltetrazines	16
Targeted Delivery of Cabazitaxel Using Cyclic Cell-Penetrating Peptide and Biomarkers of Extracellular Matrix for Prostate and Breast Cancer Therapy	16
A Novel NAMPT Inhibitor-Based Antibody–Drug Conjugate Payload Class for Cancer Therapy	16
Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells	16
Gold Nanoparticles as Carriers for Functional RNA Nanostructures	16
DiPODS: A Reagent for Site-Specific Bioconjugation via the Irreversible Rebridging of Disulfide Linkages	16
Targeted In Vivo Loading of Red Blood Cells Markedly Prolongs Nanocarrier Circulation	16
Stable and Highly Efficient Antibody–Nanoparticles Conjugation	16
Hypoxia-Activated Prodrug Enabling Synchronous Chemotherapy and HIF-1α Downregulation for Tumor Treatment	16
Surface Modification of Nanoparticles Enhances Drug Delivery to the Brain and Improves Survival in a Glioblastoma Multiforme Murine Model	15
Resveratrol Carbon Dots Disrupt Mitochondrial Function in Cancer Cells	15
Folic Acid-Functionalized Nanomedicine: Folic Acid Conjugated Copolymer and Folate Receptor Interactions Disrupt Receptor Functionality Resulting in Dual Therapeutic Anti-Cancer Potential in Breast an	15
Condensation of DNA-Conjugated Imines with Homophthalic Anhydride for the Synthesis of Isoquinolones on DNA	15
Pam3CSK4-CDGSF Augments Antitumor Immunotherapy by Synergistically Activating TLR1/2 and STING	15
Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model	15
NIR II Luminescence Imaging for Sentinel Lymph Node and Enhanced Chemo-/Photothermal Therapy for Breast Cancer	14
Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine	14
Solid-Phase Assembly of Multienzyme Systems into Artificial Cellulosomes	14
ImmunoPET of CD146 in Orthotopic and Metastatic Breast Cancer Models	14
Theranostic Activity of Nitric Oxide-Releasing Carbon Quantum Dots	14
Acoustically Detonated Microbubbles Coupled with Low Frequency Insonation: Multiparameter Evaluation of Low Energy Mechanical Ablation	14
Insight into the Covalently Oriented Immobilization of Antibodies on Gold Nanoparticle Probes to Improve Sensitivity in the Colorimetric Detection of Listeria monocytogenes	14
Development of Red-Emissive Carbon Dots for Bioimaging through a Building Block Approach: Fundamental and Applied Studies	14
Cyclodextrin/Adamantane-Mediated Targeting of Inoculated Bacteria in Mice	14
The Role of Ultrasound in Modulating Interstitial Fluid Pressure in Solid Tumors for Improved Drug Delivery	14
Amino BODIPY-Based Blue Fluorescent Probes for Aldehyde Dehydrogenase 1-Expressing Cells	14
Facile Synthesis of a Redox-Responsive Hyperbranched Polymer Prodrug as a Unimolecular Micelle for the Tumor-Selective Drug Delivery	14
Organometallic S-arylation Reagents for Rapid PEGylation of Biomolecules	14
Efficient Labeling of Native Human IgG by Proximity-Based Sortase-Mediated Isopeptide Ligation	14
Innovative Bioconjugation Technology for Antibody–Drug Conjugates: Proof of Concept in a CD30-Positive Lymphoma Mouse Model	14
Chemo-Enzymatic PEGylation/POxylation of Murine Interleukin-4	13
A Simple and Efficient Method to Generate Dual Site-Specific Conjugation ADCs with Cysteine Residue and an Unnatural Amino Acid	13
Nanopaper Biosensors at Point of Care	13
Site-Specific, Platform-Based Conjugation Strategy for the Synthesis of Dual-Labeled Immunoconjugates for Bimodal PET/NIRF Imaging of HER2-Positive Tumors	13
Combining Doxorubicin-Conjugated Polymeric Nanoparticles and 5-Aminolevulinic Acid for Enhancing Radiotherapy against Lung Cancer	13
HaloTag Forms an Intramolecular Disulfide	13
Protein Corona Formation on Lipid Nanoparticles Negatively Affects the NLRP3 Inflammasome Activation	13
RGD-Modified Titanium as an Improved Osteoinductive Biomaterial for Use in Dental and Orthopedic Implants	13
Dexamethasone and Fumaric Acid Ester Conjugate Synergistically Inhibits Inflammation and NF-κB in Macrophages	13
Recent Progress of Surface Modified Nanomaterials for Scavenging Reactive Oxygen Species in Organism	13
Development of [18F]AmBF3 Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [18F]AmBF3-PEG7-Tyr3-Octr	13
Liver Phosphoenolpyruvate Carboxykinase-1 Downregulation via siRNA-Functionalized Graphene Oxide Nanosheets Restores Glucose Homeostasis in a Type 2 Diabetes Mellitus In Vivo Model	12
Macrophage Reprogramming via Targeted ROS Scavenging and COX-2 Downregulation for Alleviating Inflammation	12
Lighting Up the Thrombin-Binding Aptamer G-Quadruplex with an Internal Cyanine-Indole-Quinolinium Nucleobase Surrogate. Direct Fluorescent Intensity Readout for Thrombin Binding without Topology Switc	12
Using Spectroscopy to Guide the Adaptation of Aptamers into Electrochemical Aptamer-Based Sensors	12
Cyclic Thiosulfinates as a Novel Class of Disulfide Cleavable Cross-Linkers for Rapid Hydrogel Synthesis	12
Influence of Riboflavin Targeting on Tumor Accumulation and Internalization of Peptostar Based Drug Delivery Systems	12
Synthesis and In Vivo Evaluation of a Site-specifically Labeled Radioimmunoconjugate for Dual-Modal (PET/NIRF) Imaging of MT1-MMP in Sarcomas	12
Gemcitabine Lipid Prodrugs: The Key Role of the Lipid Moiety on the Self-Assembly into Nanoparticles	12
Transferrin Aptamers Increase the In Vivo Blood–Brain Barrier Targeting of Protein Spherical Nucleic Acids	12
DNA Compatible Oxidization and Amidation of Terminal Alkynes	12
Bioderived Lipoic Acid-Based Dynamic Covalent Nanonetworks of Poly(disulfide)s: Enhanced Encapsulation Stability and Cancer Cell-Selective Delivery of Drugs	12
Flavin-Conjugated Nanobombs: Key Structural Requirements Governing Their Self-Assemblies’ Morphologies	12
Dual Site-Selective Presentation of Functional Handles on Protein-Engineered Cowpea Chlorotic Mottle Virus-Like Particles	12
DNA-Compatible Synthesis of α,β-Epoxyketones for DNA-Encoded Chemical Libraries	12
Simultaneous Dual-Sensing Platform Based on Aptamer-Functionalized DNA Hydrogels for Visual and Fluorescence Detection of Chloramphenicol and Aflatoxin M1	12
Hybridization-Sensitive Fluorescent Probes for DNA and RNA by a Modular “Click” Approach	12

Porous Silicon Nanoparticles Targeted to the Extracellular Matrix for Therapeutic Protein Delivery in Traumatic Brain Injury	12
Optimization of Enzymolysis Clearance Strategy To Enhance Renal Clearance of Radioligands	12
IgG-Binding Nanobody Capable of Prolonging Nanobody-Based Radiotracer Plasma Half-Life and Enhancing the Efficacy of Tumor-Targeted Radionuclide Therapy	12
Harnessing DNA Nanotechnology and Chemistry for Applications in Photonics and Electronics	12
Traceless Click-Assisted Native Chemical Ligation Enabled by Protecting Dibenzocyclooctyne from Acid-Mediated Rearrangement with Copper(I)	11
A Plug-and-Play Platform for the Formation of Trifunctional Cysteine Bioconjugates that also Offers Control over Thiol Cleavability	11
Epigenetic Platinum Complexes Breaking the “Eat Me/Don’t Eat Me” Balance for Enhanced Cancer Chemoimmunotherapy	11
Redox-Responsive Nanocapsules for the Spatiotemporal Release of Miltefosine in Lysosome: Protection against Leishmania	11
Positron Emission Tomography Tracer Design of Targeted Synthetic Peptides via 18F-Sydnone Alkyne Cycloaddition	11
A Series of Furimazine Derivatives for Sustained Live-Cell Bioluminescence Imaging and Application to the Monitoring of Myogenesis at the Single-Cell Level	11
Moving Protein PEGylation from an Art to a Data Science	11
H4picoopa─Robust Chelate for 225Ac/111In Theranostics	11
Controlled Monofunctionalization of Molecular Spherical Nucleic Acids on a Buckminster Fullerene Core	11
Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release	11
Strain-Promoted Azide–Alkyne Cycloaddition-Based PSMA-Targeting Ligands for Multimodal Intraoperative Tumor Detection of Prostate Cancer	11
Quantitative Analysis and Optimization of Site-Specific Protein Bioconjugation in Mammalian Cells	11
Artificial Nanocage Formed via Self-Assembly of β-Annulus Peptide for Delivering Biofunctional Proteins into Cell Interiors	11
Non-Genetic Generation of Antibody Conjugates Based on Chemoenzymatic Tyrosine Click Chemistry	11
Exo-Enzymatic Addition of Diazirine-Modified Sialic Acid to Cell Surfaces Enables Photocrosslinking of Glycoproteins	11
C–S Coupling of DNA-Conjugated Aryl Iodides for DNA-Encoded Chemical Library Synthesis	11
Helix-Stabilized Cell-Penetrating Peptides for Delivery of Antisense Morpholino Oligomers: Relationships among Helicity, Cellular Uptake, and Antisense Activity	11
Fluorescein and Rhodamine B-Binding Domains from Autodisplayed Fv-Antibody Library	11
Glutathione-Responsive Chemodynamic Therapy of Manganese(III/IV) Cluster Nanoparticles Enhanced by Electrochemical Stimulation via Oxidative Stress Pathway	11
Multifunctional Neomycin-Triazine-Based Cationic Lipids for Gene Delivery with Antibacterial Properties	11
Attenuation of the Reaction of Michael Acceptors with Biologically Important Nucleophiles	11
Antibody-Mediated Screening of Peptide Inhibitors for Monoamine Oxidase-B (MAO-B) from an Autodisplayed FV Library	11
Synthesis and Evaluation of Three Azide-Modified Disaccharide Oxazolines as Enzyme Substrates for Single-Step Fc Glycan-Mediated Antibody-Drug Conjugation	11
Rapid, High-Yielding Solid-Phase Synthesis of Cathepsin-B Cleavable Linkers for Targeted Cancer Therapeutics	11
EGFR Ligand Clustering on E2 Bionanoparticles for Targeted Delivery of Chemotherapeutics to Breast Cancer Cells	11
A Comparative Analysis of Fibroblast Activation Protein-Targeted Small Molecule–Drug, Antibody–Drug, and Peptide–Drug Conjugates	10
Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism	10
Selectively Fluorinated PAMAM–Arginine Conjugates as Gene Delivery Vectors	10
New Method for Efficient siRNA Delivery in Retina Explants: Reverse Magnetofection	10
Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines	10
Dynamics of DNA Origami Lattices	10
Cationic Micelles Outperform Linear Polymers for Delivery of Antisense Oligonucleotides in Serum: An Exploration of Polymer Architecture, Cationic Moieties, and Cell Addition Order	10
Fast and Selective Reaction of 2-Benzylacrylaldehyde with 1,2-Aminothiol for Stable N-Terminal Cysteine Modification and Peptide Cyclization	10
Cucurbituril–Ferrocene: Host–Guest Based Pretargeted Positron Emission Tomography in a Xenograft Model	10
Poly(hydrophobic amino acid) Conjugates for the Delivery of Multiepitope Vaccine against Group A Streptococcus	10
Engineering PEGylated Polyester Nanoparticles to Reduce Complement-Mediated Infusion Reaction	10
FRET-Based Method for Direct, Real-Time Measurement of DNA Methyltransferase Activity	10
An Integrated Tumor Microenvironment Responsive Polymeric Micelle for Smart Drug Delivery and Effective Drug Release	10
Synthesis and Comparative In Vivo Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET	10
Iridium(III) Complex-Loaded Perfluoropropane Nanobubbles for Enhanced Sonodynamic Therapy	10
MMP-2-Activatable Photoacoustic Tumor Imaging Probes Based on Al- and Si-Naphthalocyanines	10
Directly Quantifiable Biotinylation Using a Water-Soluble Isatoic Anhydride Platform	10
Portfolio Targeting Strategy To Realize the Assembly and Membrane Fusion-Mediated Delivery of Gold Nanoparticles to Mitochondria for Enhanced NIR Photothermal Therapies	10
Piggybacking on the Cholera Toxin: Identification of a CTB-Binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons	10
Structural Investigations, Cellular Imaging, and Radiolabeling of Neutral, Polycationic, and Polyanionic Functional Metalloporphyrin Conjugates	10
Isotope-Coded Maleimide Affinity Tags for Proteomics Applications	10
Enhancing Cancer Immunotherapeutic Efficacy with Sonotheranostic Strategies	10
Mitochondria-Targeting Polyprodrugs to Overcome the Drug Resistance of Cancer Cells by Self-Amplified Oxidation-Triggered Drug Release	10
Targeting Colon Cancer Cells with Enzyme-Triggered Casein-Gated Release of Cargo from Mesoporous Silica-Based Nanoparticles	10
SARS-CoV-2 Peptide Bioconjugates Designed for Antibody Diagnostics	10
Potentiating the Membrane Interaction of an Attenuated Cationic Amphiphilic Lytic Peptide for Intracellular Protein Delivery by Anchoring with Pyrene Moiety	10
Synthesis and Evaluation of Ubiquitin–Dioxetane Conjugate as a Chemiluminescent Probe for Monitoring Deubiquitinase Activity	10
AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody–Drug Conjugate Production	9
Orthogonal Enzymatic Conjugation Reactions Create Chitin Binding Domain Grafted Chitinase Polymers with Enhanced Antifungal Activity	9
Radiolabeling Optimization and Preclinical Evaluation of the New PSMA Imaging Agent [18F]AlF-P16-093	9
Reversible Control of DNA Binding with Cucurbit[8]uril-Induced Supramolecular 4,4′-Bipyridinium–Peptide Dimers	9
Zinc Triggered Release of Encapsulated Cargo from Liposomes via a Synthetic Lipid Switch	9
Spotlight on Photoactivatable Liposomes beyond Drug Delivery: An Enabler of Multitargeting of Molecular Pathways	9
Extending the Half-Life of a Protein in Vivo by Enzymatic Labeling with Amphiphilic Lipopeptides	9
Photooxidation Responsive Elastin-Like Polypeptide Conjugates for Photodynamic Therapy Application	9
Evaluation of Cellular Targeting by Fab′ vs Full-Length Antibodies in Antibody–Nanoparticle Conjugates (ANCs) Using CD4 T-cells	9
6-Iodopurine as a Versatile Building Block for RNA Purine Architecture Modifications	9
A Photoacoustic Contrast Agent for miR-21 via NIR Fluorescent Hybridization Chain Reaction	9
Prostate-Specific Membrane Antigen-Targeted Turn-on Probe for Imaging Cargo Release in Prostate Cancer Cells	9
On-DNA Alkyne Iodination and Acetylenic Coupling as a Useful Tool for DEL Synthesis	9
Supernatural: Artificial Nucleobases and Backbones to Program Hybridization-Based Assemblies and Circuits	9
Peptide-Folding Triggered Phase Separation and Lipid Membrane Destabilization in Cholesterol-Rich Lipid Vesicles	9
Image-Guided Enhanced PDT/PTT Combination Therapy Using Brominated Hemicyanine-Loaded Folate Receptor-Targeting Ag2S Quantum Dots	9
Ratiometric Fluorescence Monitoring of Antibody-Guided Drug Delivery to Cancer Cells	9
Effect of PEGylation on Host Defense Peptide Complexation with Bacterial Lipopolysaccharide	9
Targeted Anti-Cancer Provascular Therapy Using Ultrasound, Microbubbles, and Nitrite to Increase Radiotherapy Efficacy	9
Copper-Free Click Enabled Triazabutadiene for Bioorthogonal Protein Functionalization	9
On-DNA Palladium-Catalyzed Hydrogenation-like Reaction Suitable for DNA-Encoded Library Synthesis	9
Design, Synthesis, and Anticancer Activity of Triptycene–Peptide Hybrids that Induce Paraptotic Cell Death in Cancer Cells	9
A Self-Assembling Probe for Imaging the States of Golgi Apparatus in Live Single Cells	9
211At-Labeled Polymer Nanoparticles for Targeted Radionuclide Therapy of Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR)-Overexpressed Cancer	9
Design of Neuraminidase-Targeted Imaging and Therapeutic Agents for the Diagnosis and Treatment of Influenza Virus Infections	9
Photoactivated Nanohybrid for Dual-Nuclei MR/US/PA Multimodal-Guided Photothermal Therapy	9
Intracellular Uptake Mechanism of Bioorthogonally Conjugated Nanoparticles on Metabolically Engineered Mesenchymal Stem Cells	9
Easy Surface Functionalization and Bioconjugation of Peptides as Capture Agents of a Microfluidic Biosensing Platform for Multiplex Assay in Serum	9
Therapeutic Targeting of Tumor Cells Rich in LGR Stem Cell Receptors	9
Trifluorinated Keto–Enol Tautomeric Switch in Probing Domain Rotation of a G Protein-Coupled Receptor	8
Dimeric Metal-Salphen Complexes Which Target Multimeric G-Quadruplex DNA	8
3D Printed Multifunctional Ti6Al4V-Based Hybrid Scaffold for the Management of Osteosarcoma	8
DOTAM-Based, Targeted, Activatable Fluorescent Probes for the Highly Sensitive and Selective Detection of Cancer Cells	8
Biotin–NeutrAvidin Mediated Immobilization of Polymer Micro- and Nanoparticles on T Lymphocytes	8
New Phenol Esters for Efficient pH-Controlled Amine Acylation of Peptides, Proteins, and Sepharose Beads in Aqueous Media	8
Synthesis and Characterization of a Positron Emission Tomography Imaging Probe Selectively Targeting the Second Bromodomain of Bromodomain Protein BRD4	8
Hydrolytically Stable Maleimide-End-Functionalized Polymers for Site-Specific Protein Conjugation	8
Synthesis of First Coumarin Fluorescent Dye for Actin Visualization	8
Stimuli-Responsive Regulation of Biocatalysis through Metallic Nanoparticle Interaction	8