OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Toxicology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
The synthetic cannabinoids phenomenon: from structure to toxicological properties. A review	93
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?	79
Consequences of chemical impact of disinfectants: safe preventive measures against COVID-19	67
A review of toxic effects of electronic cigarettes/vaping in adolescents and young adults	52
Pyrethroid based pesticides – chemical and biological aspects	49
The aging brain: impact of heavy metal neurotoxicity	47
Toxicity of bisphenol analogues on the reproductive, nervous, and immune systems, and their relationships to gut microbiome and metabolism: insights from a multi-species comparison	46
Associations between exposure to heavy metals and the risk of chronic kidney disease: a systematic review and meta-analysis	44
Simulated biological fluids – a systematic review of their biological relevance and use in relation to inhalation toxicology of particles and fibres	44
The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis	35
Aluminum reproductive toxicity: a summary and interpretation of scientific reports	33
Treating organophosphates poisoning: management challenges and potential solutions	33
An update on the hazard of and exposure to diethyl hexyl phthalate (DEHP) alternatives used in medical devices	31
Three-dimensional liver models: state of the art and their application for hepatotoxicity evaluation	29
Distribution and translocation of micro- and nanoplastics in fish	27
A national toxicology program systematic review of the evidence for long-term effects after acute exposure to sarin nerve agent	26
Inflammation, oxidative stress and genotoxicity responses to biodiesel emissions in cultured mammalian cells and animals	24
The estrogenic activity of resveratrol: a comprehensive review ofin vitroandin vivoevidence and the potential for endocrine disruption	24
Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism	24
Systematic review of the potential respiratory carcinogenicity of metallic nickel in humans	20
An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: a case study with hexavalent chromium, captan, and folpet	19
Towards a mechanism-based approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals	19
Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR)	19
Ah receptor ligands and their impacts on gut resilience: structure–activity effects	18
Effects of BPA substitutes on the prenatal and cardiovascular systems	16

Sexual dimorphism in placental development and its contribution to health and diseases	13
Methodological considerations for measuring biofluid-based microRNA biomarkers	13
Applicability of organ-on-chip systems in toxicology and pharmacology	12
An integrative translational framework for chemical induced neurotoxicity – a systematic review	12
E-cigarette vaping associated acute lung injury (EVALI): state of science and future research needs	12
The effects of bisphenols on the cardiovascular system	12
The health effects of short fiber chrysotile and amphibole asbestos	11
EDC-induced mechanisms of immunotoxicity: a systematic review	11
Insights and controversies on sunscreen safety	11
A meta-analysis of preclinical studies using antioxidants for the prevention of cisplatin nephrotoxicity: implications for clinical application	11
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways	11
Critical review and analysis of literature on low dose exposure to chemical mixtures in mammalian in vivo systems	11
Extracellular vesicles as actors in the air pollution related cardiopulmonary diseases	11
Is insulin intoxication still the perfect crime? Analysis and interpretation of postmortem insulin: review and perspectives in forensic toxicology	11
Determination of the relative allergenic potency of proteins: hurdles and opportunities	10
Assessing chemical carcinogenicity: hazard identification, classification, and risk assessment. Insight from a Toxicology Forum state-of-the-science workshop	10
Identifying a reference list of respiratory sensitizers for the evaluation of novel approaches to study respiratory sensitization	10
Biomarkers of environmental manganese exposure	10
Review of the mechanism underlying mefloquine-induced neurotoxicity	9
The role of vitamin E acetate (VEA) and its derivatives in the vaping associated lung injury: systematic review of evidence	9
Designer benzodiazepines versus prescription benzodiazepines: can structural relation predict the next step?	9
Mycotoxin exposure and pregnancy	8
Molecular and epigenetic modes of Fumonisin B₁ mediated toxicity and carcinogenesis and detoxification strategies	8
Blood lead concentration among oral/inhaled opium users: systematic review and meta-analysis	8
Combining ecstasy and ethanol: higher risk for toxicity? A review	8
Does ozone inhalation cause adverse metabolic effects in humans? A systematic review	8
An overview of current practices for regulatory risk assessment with lessons learnt from cosmetics in the European Union	7
Lung macrophages: current understanding of their roles in Ozone-induced lung diseases	7
An examination of historical control histopathology metadata from 51 Amphibian Metamorphosis Assays	7
Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part I: which parameters from human studies are most relevant for	7
Application of adverse outcome pathway networks to integrate mechanistic data informing the choice of a point of departure for hydrogen sulfide exposure limits	7
Relevance of animal studies in the toxicological assessment of oil and wax hydrocarbons. Solving the puzzle for a new outlook in risk assessment	7
Whether drug detection in urine and oral fluid is similar? A systematic review	7
An updated mode of action and human relevance framework evaluation for Formaldehyde-Related nasal tumors	7
A critical review of the 2020 EPA risk assessment for chrysotile and its many shortcomings	7
Weight of evidence analysis of the tumorigenic potential of 1,3-dichloropropene supports a threshold-based risk assessment	7
Using mechanistic information to support evidence integration and synthesis: a case study with inhaled formaldehyde and leukemia	6
RNA A-to-I editing, environmental exposure, and human diseases	6
Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts	6
The shape of low-concentration dose–response functions for benzene: implications for human health risk assessment	6
Using existing knowledge for the risk evaluation of crop protection products in order to guide exposure driven data generation strategies and minimise unnecessary animal testing	6
The methodological rigour of systematic reviews in environmental health	6
A systematic review on fluoride-induced epigenetic toxicity in mammals	5
Biomarkers for occupational manganese exposure	5
Risk characterisation of constituents present in jamu to promote its safe use	5
Projection of future numbers of mesothelioma cases in the US and the increasing prevalence of background cases: an update based on SEER data for 1975 through 2018	5
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny—part III: how is substance-mediated thyroid hormone imbalance in p	5
Using Bayesian networks to clarify interpretation of exposure–response regression coefficients: blood lead–mortality association as an example	5
Framework for sensitization assessment of extractables and leachables in pharmaceuticals	5
A critical review of the kinetic direct peptide reactivity assay (kDPRA) for skin sensitizer potency assessment – taking it forward	5

Using the Matrix to bridge the epidemiology/risk assessment gap: a case study of 2,4-D	4
Human biomonitoring of low-level benzene exposures	4
Assessment of metal ion accumulation in oral mucosa cells of patients with fixed orthodontic treatment and cellular DNA damage: a systematic review	4
Recent advances in electrochemical and optical sensing of the organophosphate chlorpyrifos: a review	4
A narrative review of converging evidence addressing developmental toxicity of pyrethroid insecticides	4
Low level exposure to hydrogen sulfide: a review of emissions, community exposure, health effects, and exposure guidelines	4
Effects of pyrethroids on the cerebellum and related mechanisms: a narrative review	4
Nephrotoxicity induced by natural compounds from herbal medicines – a challenge for clinical application	4
The effect of confounding variables in studies of lead exposure and IQ	4
A broader view on deriving a reference dose for THC traces in foods	4
Mycotoxins occurrence in milk and cereals in North African countries – a review	4
Assessment of genotoxicity of glass ionomer cements: a systematic review	4