OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Toxicology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Mechanisms of developmental neurotoxicity mediated by perturbed thyroid hormone homeostasis in the brain: an adverse outcome pathway network	105
Per- and polyfluoroalkyl substances (PFAS): immunotoxicity at the primary sites of exposure	53
Thank you to Reviewers for Critical Reviews in Toxicology	51
Recent advances in electrochemical and optical sensing of the organophosphate chlorpyrifos: a review	38
Potential application of probiotics in mycotoxicosis reduction in mammals and poultry	33
Response to the letter to the editor regarding the article “Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts” by Garve	31
Effects of statins on male reproductive health: a systematic review of rodent studies and their potential implications to human male reproduction	30
Letter to the Editor: Comprehensive review of octocrylene toxicology data and human exposure assessment for personal care products	28
Examining the relationship between per-and polyfluoroalkyl substances and breast, colorectal, prostate, and ovarian cancers: a meta-analysis	28
United States Environmental Protection Agency's Perfluorooctanoic Acid, Perfluorooctane Sulfonic Acid, and Related Per- and Polyfluoroalkyl Substances 2024 Drinking Water Maximum Contaminant Level: Pa	27
Nephrotoxicity induced by natural compounds from herbal medicines – a challenge for clinical application	27
Evidence and hypotheses on adverse effects of the food additives carrageenan (E 407)/processed Eucheuma seaweed (E 407a) and carboxymethylcellulose (E 466) on the intestines: a scoping review	24
In vitro human brain barrier models for studying thyroid hormone transport	24
Thank you to authors and reviewers of papers in Critical Reviews in Toxicology (CRT) volume 54, 2024	23
The IARC re-classification of talc carcinogenicity: a move in the wrong direction?	20
Data derived extrapolation factors (DDEFs) for rat to human interspecies extrapolation for the HPPD inhibitor mesotrione	20
A systematic review on fluoride-induced epigenetic toxicity in mammals	20
Construction of a risk prediction model of diquat poisoning based on clinical indicators	18
Meta-analysis of the safety and efficacy of fresh frozen plasma exchange in the treatment of organophosphate pesticide poisoning	18
Zebrafish and nematodes as whole organism models to measure developmental neurotoxicity	18
A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles	17
In search of certainty beyond the cholinergic system: a systematic review of developmental chlorpyrifos exposure and neurotransmitter systems disruption in preclinical models	16
Evaluating health impacts of exposure to PFAS mixtures: a systematic review of epidemiological studies using mixture methods	16
Fiber biodurability and biopersistence: historical toxicological perspective of synthetic vitreous fibers (SVFs), the long fiber paradigm, and implications for advanced materials	15
Response to letter to the editor on: “the use of canonical dose–response models for benchmark dose analysis of continuous toxicological data”	15

Assessment of genotoxicity of glass ionomer cements: a systematic review	14
An updated evaluation of reported no-observed adverse effect levels for chrysotile, amosite, and crocidolite asbestos for lung cancer and mesothelioma	14
Letter to the editor regarding the review article: Yamada T, Cohen SM, Lake BG. The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the	14
Complex roles for sulfation in the toxicities of polychlorinated biphenyls	14
Synthetic vitreous fibers (SVFs): adverse outcome pathways (AOPs) and considerations for next generation new approach methods (NAMs)	13
Prevention and Detoxification of Mycotoxins in Human Food and Animal Feed using Bio-resources from South Mediterranean Countries: a Critical Review	13
Review of epidemiological and toxicological studies on health effects from ingestion of asbestos in drinking water	13
Human biomonitoring and risks of hazardous occupational exposure to polycyclic aromatic hydrocarbons in wildland fires: a critical review	12
Systematic review of studies on exposure to arsenic in drinking water and cognitive and neurobehavioral effects	12
A systematic review of herbicide safener toxicity	12
Magnetic resonance imaging T1 indices of the brain as biomarkers of inhaled manganese exposure	11
Gastrointestinal decontamination using oil-based solutions in patients with acute aluminum phosphide poisoning: a systematic review and meta-analysis	11
Wildfires in the Pan-Amazon: what is known about health impacts on affected populations?	11
Female reproductive toxicity after exposure to malathion or diazinon: a systematic review of rodent and human studies	11
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny—part III: how is substance-mediated thyroid hormone imbalance in p	11
A prioritization strategy for functional alternatives to bisphenol A in food contact materials	10
Role of constitutive androstane receptor in developmental toxicology: linking chemical exposure, nutrition, and disease susceptibility	10
Dietary psychoactive xenobiotics: an updated review on food contamination with ergot, tropane and opium alkaloids and their toxicological effects	9
What can we learn from epidemiological studies on chronic boron exposure?	9
From cultivation to cancer: formation of N -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications	9
Perspectives on aerosol inhalability: concepts and applications	9
The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to hu	9
Exploring research gaps and trends in the management of acute phosphide poisoning: a systematic review	9
A narrative review of converging evidence addressing developmental toxicity of pyrethroid insecticides	9
A quantitative weight-of-evidence review of preclinical studies examining the potential developmental and reproductive toxicity of acetaminophen	8
Comprehensive review of octocrylene toxicology data and human exposure assessment for personal care products	8
Response to the Letter from Professor C. R. Wolf and colleagues concerning CRT, 55: 549–586, 2025: The modes of action for rodent liver tumor formation by activators of the constitutive androstane rec	8
Investigations on learning and memory function in extended one-generation reproductive toxicity studies – when considered needed and based on what?	8
Mode of action approach supports a lack of carcinogenic potential of six organic UV filters	8
Malathion or diazinon exposure and male reproductive toxicity: a systematic review of studies performed with rodents	8
Mechanisms of neurodevelopmental toxicity of topiramate	8
Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats	8
Evaluating the conduct and reporting of the T-cell dependent antibody response in the Extended One-Generation Reproductive Toxicity study provided under the EU REACH regulation	8
Human biomonitoring of low-level benzene exposures	7
Letter to the editor regarding the review article by Yamada et al. (2021) titled “Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the	7
Correction	7
The use of canonical dose–response models for benchmark dose analysis of continuous toxicological data	7
A weight of evidence review on the mode of action, adversity, and the human relevance of xylene’s observed thyroid effects in rats	7
A critical review to identify data gaps and improve risk assessment of bisphenol A alternatives for human health	7
A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Part 2: framework application in four case studies	7
Fungicides as a risk factor for the development of neurological diseases and disorders in humans: a systematic review	7
Low level exposure to hydrogen sulfide: a review of emissions, community exposure, health effects, and exposure guidelines	7
25X-NBOMe compounds – chemistry, pharmacology and toxicology. A comprehensive review	6
Mechanistic insights regarding neuropsychiatric and neuropathologic impacts of air pollution	6
European Food Safety Authority database for in vivo developmental neurotoxicity studies of pesticides	6
Animal models of developmental toxicity induced by early life electronic-cigarettes exposure	6
Correction	6
Toxicity of chemical-based hand sanitizers on children and the development of natural alternatives: a computational approach	5
Non-acute exposure of neonicotinoids, health risk assessment, and evidence integration: a systematic review	5
Molecular similarity in chemical informatics and predictive toxicity modeling: from quantitative read-across (q-RA) to quantitative read-across structure–activity relationship (q-RASAR) with the appli	5

Diagnosis, toxicological mechanism, and detoxification for hepatotoxicity induced by pyrrolizidine alkaloids from herbal medicines or other plants	5
Modeling the human placenta: in vitro applications in developmental and reproductive toxicology	4
The tradeoff between the efficacy of calcineurin inhibitors: prevention of allograft rejection vs. post-transplant renal and cardiovascular complications	4
A quantitative weight-of-evidence review of preclinical studies examining the potential developmental neurotoxicity of acetaminophen	4
Response to Letter to the Editor from Drs. van Kesteren, Pronk, Heusinkveld, Luijten and Hakkert concerning Yamada et al. (2021): Critical evaluation of the human relevance of the mode of action for r	4
Necessary conditions for valid causal inference from observational data	4
A framework for integrating evidence to assess hazards and risk	4
The skin sensitization adverse outcome pathway: exploring the role of mechanistic understanding for higher tier risk assessment	4
Mycotoxins occurrence in milk and cereals in North African countries – a review	4
Genotoxic and epigenetic signatures of early-life pesticide exposure: a systematic review and meta-analysis	4
Regulatory roles of extracellular vesicles in adverse pregnancy outcomes exposed with environmental toxicants	4