OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Toxicology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?	97
Toxicity of bisphenol analogues on the reproductive, nervous, and immune systems, and their relationships to gut microbiome and metabolism: insights from a multi-species comparison	59
Simulated biological fluids – a systematic review of their biological relevance and use in relation to inhalation toxicology of particles and fibres	58
Pyrethroid based pesticides – chemical and biological aspects	57
Associations between exposure to heavy metals and the risk of chronic kidney disease: a systematic review and meta-analysis	54
The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis	47
Distribution and translocation of micro- and nanoplastics in fish	44
Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism	38
E-cigarette vaping associated acute lung injury (EVALI): state of science and future research needs	23
Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR)	22
Assessing chemical carcinogenicity: hazard identification, classification, and risk assessment. Insight from a Toxicology Forum state-of-the-science workshop	20
The effects of bisphenols on the cardiovascular system	18
Methodological considerations for measuring biofluid-based microRNA biomarkers	17
Low level exposure to hydrogen sulfide: a review of emissions, community exposure, health effects, and exposure guidelines	17
Effects of BPA substitutes on the prenatal and cardiovascular systems	17
Applicability of organ-on-chip systems in toxicology and pharmacology	16
The health effects of short fiber chrysotile and amphibole asbestos	16
Sexual dimorphism in placental development and its contribution to health and diseases	16
Critical review and analysis of literature on low dose exposure to chemical mixtures in mammalian in vivo systems	14
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways	13
Identifying a reference list of respiratory sensitizers for the evaluation of novel approaches to study respiratory sensitization	13
Biomarkers of environmental manganese exposure	13
Using mechanistic information to support evidence integration and synthesis: a case study with inhaled formaldehyde and leukemia	12
Review of the mechanism underlying mefloquine-induced neurotoxicity	11
A critical review of the 2020 EPA risk assessment for chrysotile and its many shortcomings	11

EDC-induced mechanisms of immunotoxicity: a systematic review	11
Cadmium exposure and DNA damage (genotoxicity): a systematic review and meta-analysis	10
Molecular and epigenetic modes of Fumonisin B₁ mediated toxicity and carcinogenesis and detoxification strategies	10
An updated mode of action and human relevance framework evaluation for Formaldehyde-Related nasal tumors	10
Designer benzodiazepines versus prescription benzodiazepines: can structural relation predict the next step?	10
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny—part III: how is substance-mediated thyroid hormone imbalance in p	10
An overview of current practices for regulatory risk assessment with lessons learnt from cosmetics in the European Union	10
Combining ecstasy and ethanol: higher risk for toxicity? A review	9
Application of adverse outcome pathway networks to integrate mechanistic data informing the choice of a point of departure for hydrogen sulfide exposure limits	9
An examination of historical control histopathology metadata from 51 Amphibian Metamorphosis Assays	9
Weight of evidence analysis of the tumorigenic potential of 1,3-dichloropropene supports a threshold-based risk assessment	9
Projection of future numbers of mesothelioma cases in the US and the increasing prevalence of background cases: an update based on SEER data for 1975 through 2018	9
The shape of low-concentration dose–response functions for benzene: implications for human health risk assessment	9
Biomarkers for occupational manganese exposure	9
The role of vitamin E acetate (VEA) and its derivatives in the vaping associated lung injury: systematic review of evidence	9
The methodological rigour of systematic reviews in environmental health	9
Does ozone inhalation cause adverse metabolic effects in humans? A systematic review	9
Blood lead concentration among oral/inhaled opium users: systematic review and meta-analysis	8
RNA A-to-I editing, environmental exposure, and human diseases	8
A narrative review of converging evidence addressing developmental toxicity of pyrethroid insecticides	8
Systematic review of epidemiological and toxicological evidence on health effects of fluoride in drinking water	8
Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts	7
Mycotoxins occurrence in milk and cereals in North African countries – a review	7
A critical review of the kinetic direct peptide reactivity assay (kDPRA) for skin sensitizer potency assessment – taking it forward	7
A broader view on deriving a reference dose for THC traces in foods	7
Relevance of animal studies in the toxicological assessment of oil and wax hydrocarbons. Solving the puzzle for a new outlook in risk assessment	7
Regulatory roles of non-coding RNAs and m6A modification in trophoblast functions and the occurrence of its related adverse pregnancy outcomes	7
A systematic review on fluoride-induced epigenetic toxicity in mammals	7
Risk characterisation of constituents present in jamu to promote its safe use	6
Framework for sensitization assessment of extractables and leachables in pharmaceuticals	6
Nephrotoxicity induced by natural compounds from herbal medicines – a challenge for clinical application	6
Using existing knowledge for the risk evaluation of crop protection products in order to guide exposure driven data generation strategies and minimise unnecessary animal testing	6
Human biomonitoring of low-level benzene exposures	6
Clearance, biodistribution, and neuromodulatory effects of aluminum-based adjuvants. Systematic review and meta-analysis: what do we learn from animal studies?	6
Molecular insights into the role of electronic cigarettes in oral carcinogenesis	6
Effects of pyrethroids on the cerebellum and related mechanisms: a narrative review	6
Assessment of genotoxicity of glass ionomer cements: a systematic review	6
Assessment of metal ion accumulation in oral mucosa cells of patients with fixed orthodontic treatment and cellular DNA damage: a systematic review	5
Using the Matrix to bridge the epidemiology/risk assessment gap: a case study of 2,4-D	5
Potential application of probiotics in mycotoxicosis reduction in mammals and poultry	5
Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats	5
Occupational exposure assessment with solid substances: choosing a vehicle for in vitro percutaneous absorption experiments	5
Procedural application of mode-of-action and human relevance analysis: styrene-induced lung tumors in mice	4
Overview of analytical methods for determining novel psychoactive substances, drugs and their metabolites in biological samples	4
Hazards of current concentration-setting practices in environmental toxicology studies	4
Tefluthrin: metabolism, food residues, toxicity, and mechanisms of action	4
Methyl methacrylate and respiratory sensitisation: a comprehensive review	4
Recent advances in electrochemical and optical sensing of the organophosphate chlorpyrifos: a review	4
Immunotoxicity of engineered nanomaterials and their role in asthma	3
Malathion or diazinon exposure and male reproductive toxicity: a systematic review of studies performed with rodents	3

25X-NBOMe compounds – chemistry, pharmacology and toxicology. A comprehensive review	3
Non-clinical toxicology evaluation of BIA 10-2474	3
Implementation of a dermal sensitization threshold (DST) concept for risk assessment: structure-based DST and in vitro data-based DST	3
Evidence and hypotheses on adverse effects of the food additives carrageenan (E 407)/processed Eucheuma seaweed (E 407a) and carboxymethylcellulose (E 466) on the intestines: a scoping review	3
Human chlorine gas exposition and its management – an umbrella review on human data	3
From cultivation to cancer: formation of N -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications	3
Radiological risk assessment of the Hunters Point Naval Shipyard (HPNS)	3
A review of mammalianin vivogenotoxicity of hexavalent chromium: implications for oral carcinogenicity risk assessment	3
Hydrogen sulfide poisoning in forensic pathology and toxicology: mechanism and metabolites quantification analysis	3
Exploring research gaps and trends in the management of acute phosphide poisoning: a systematic review	3
A mechanistic evaluation of the potential for octamethylcyclotetrasiloxane to produce effects via endocrine modes of action	3