Critical Reviews in Oncology Hematology

Article	Citations
Harnessing tumor metabolism during cancer treatment: A narrative review of emerging dietary approaches	168
Letter to the Editor regarding the article “A net-work meta-analysis of the cardiac safety for next-generation hormonal agents in treating castration-resistant prostate cancer: How to choose drugs app	163
Thrombotic microangiopathy (aHUS/iTTP) reported so far in Covid-19 patients: The virus alone or an omnium gatherum of mechanisms and etiologies?	139
Navigating management of localized prostate cancer in the geriatric population	120
Hurrying up but not rushing, acting and not reacting, good sense and not common sense: Open thoughts and reasonable doubts on COVID-19 vaccination strategies in cancer patients	106
Tyrosine kinase inhibitors in cancers: Treatment optimization – Part II	97
A non-invasive miRNA-based approach in early diagnosis and therapeutics of oral cancer	85
Efficacy of PD-1/PD-L1 immunotherapy on brain metastatic non-small-cell lung cancer and treatment-related adverse events: A systematic review	80
Skin barrier dysfunction in cutaneous T-cell lymphoma: From pathogenic mechanism of barrier damage to treatment	75
Dysregulation of systemic immunity in colorectal cancer and its clinical applications as biomarkers and therapeutics	66
Instruments and scales for the evaluation of acute radiation dermatitis: A systematic review	60
Development of treatment strategies for advanced HER2-positive gastric cancer: Insights from clinical trials	59
Editorial Board	58
A bone paradigm challenging the standard model of myeloma oncogenesis	58
Direct and indirect effects on child neurocognitive development when maternal cancer is diagnosed during pregnancy: What do we know so far?	58
Open issues in the therapeutic management of unresectable stage III NSCLC in the immunotherapy era	55
Stereotactic body radiation therapy versus conventional external beam radiation therapy for painful bone metastases: A systematic review and meta-analysis of randomized trials	55
Current status of locally advanced rectal cancer therapy and future prospects	53
Total neoadjuvant treatment and organ preservation strategies in the management of localized rectal cancer: A narrative review and evidence-based algorithm	51
Next generation diagnostic algorithm in non-small cell lung cancer predictive molecular pathology: The KWAY Italian multicenter cost evaluation study	50
Mapping the research landscape of HPV-positive oropharyngeal cancer: a bibliometric analysis	50
Double agents in immunotherapy: Unmasking the role of antibody drug conjugates in immune checkpoint targeting	49
Microbiome and lung cancer: carcinogenic mechanisms, early cancer diagnosis, and promising microbial therapies	49
Innovations in cancer immunotherapy: A comprehensive overview of recent breakthroughs and future directions	48
The role of cGAS-STING in remodeling the tumor immune microenvironment induced by radiotherapy	46

The cytokines in tumor microenvironment: from cancer initiation-elongation-progression to metastatic outgrowth	45
Advancing tumor vaccines: Overcoming TME challenges, delivery strategies, and biomaterial-based vaccine for enhanced immunotherapy	40
Apigenin in cancer prevention and therapy: A systematic review and meta-analysis of animal models	40
First-line treatments for advanced or recurrent endometrial cancer: Systematic literature review of clinical evidence	39
Meta-analysis of immune-related adverse events in phase 3 clinical trials assessing immune checkpoint inhibitors for lung cancer	38
Chemotherapy, immunotherapy, and targeted therapy for osteosarcoma: Recent advancements	38
Exosomes derived from cancer-associated fibroblasts mediate response to cancer therapy	37
TIGIT: Will it be the next star therapeutic target like PD-1 in hematological malignancies?	37
Thrombosis and cachexia in cancer: Two partners in crime?	37
Immunotherapy in OSCC: Current trend and challenges	37
Neoadjuvant therapy for muscle-invasive bladder cancer: Current clinical scenario, future perspectives, and unsolved questions	36
The biology and treatment of leiomyosarcomas	36
Effect of exercise on functional capacity in patients with advanced cancer: A meta-analysis of randomized controlled trials	35
Cellular and molecular mechanisms implicated in the dual role of ROR2 in cancer	35
Editorial Board	34
Advantages and drawbacks of dexamethasone in glioblastoma multiforme	34
ESO's career development program (2002-2021): Presentation and evaluation	34
Predictive factors for return to work among cancer survivors in Europe: A systematic review	34
Targeting hypoxia-inducible factor pathways in sporadic and Von Hippel-Lindau syndrome-related kidney cancers	33
Optimal treatment strategy for central nervous system non-germinomatous germ cell tumors: A systematic review and meta-analysis	33
Immuno-oncology therapy in metastatic bladder cancer: A systematic review and network meta-analysis	32
Comment on “The risk of breast cancer and gynecologic malignancies after ovarian stimulation: Meta-analysis of cohort study”	31
Management of secondary immunodeficiency in hematological malignancies in the era of modern oncology	31
Impact of immune cells on the hallmarks of cancer: A literature review	30
Can inflammasomes promote the pathophysiology of glioblastoma multiforme? A view about the potential of the anti-inflammasome therapy as pharmacological target	30
Platelet-mediated tumor metastasis mechanism and the role of cell adhesion molecules	30
KRAS mutated colorectal cancers with or without PIK3CA mutations: Clinical and molecular profiles inform current and future therapeutics	30
Circulating tumor cell detection methods in renal cell carcinoma: A systematic review	30
UGT1A1 Testing in Breast Cancer: should it become routine practice in patients treated with antibody-drug conjugates?	30
Exposure to endocrine disruptors and risk of breast cancer: A systematic review	29
Pressurised intraperitoneal aerosolised chemotherapy (PIPAC) for gastric cancer with peritoneal metastases: A systematic review by the PIPAC UK collaborative	29
Minimal residual disease testing for classical Hodgkin lymphoma: A comprehensive review	28
CAR T-cell therapy landscape in pediatric, adolescent and young adult oncology – A comprehensive analysis of clinical trials	28
DLL3 as a potential diagnostic and therapeutic target in neuroendocrine neoplasms: A narrative review	28
Unraveling molecular mechanisms of head and neck cancer	28
A systematic review of systematic reviews and pooled meta-analysis on pharmacological interventions to improve cancer-related fatigue	28
Bone health in glucocorticoid-treated childhood acute lymphoblastic leukemia	28
Quantifying absolute benefit for adjuvant treatment options in renal cell carcinoma: A living interactive systematic review and network meta-analysis	27
Unlocking the potential of Molecular Tumor Boards: from cutting-edge data interpretation to innovative clinical pathways	26
Prognostic scores including peripheral blood-derived inflammatory indices in patients with advanced non-small-cell lung cancer treated with immune checkpoint inhibitors	26
Synergistic effects of immunotherapy and adjunctive therapies in prostate cancer management	26
Efficacy of stereotactic radiosurgery as single or combined therapy for brain metastasis: A systematic review and meta-analysis	26
The role of liquid biopsy in epithelial ovarian cancer: State of the art	26
The role of central nervous system (CNS) prophylaxis in preventing DLBCL patients from CNS relapse: A network meta-analysis	26
Sialylated glycoproteins and sialyltransferases in digestive cancers: Mechanisms, diagnostic biomarkers, and therapeutic targets	25
Facing the climate change: Is radiotherapy as green as we would like? A systematic review	25
The extracellular matrix in colorectal cancer and its metastatic settling – Alterations and biological implications	25
Combining gut microbiota modulation and immunotherapy: A promising approach for treating microsatellite stable colorectal cancer	24
The association between paraneoplastic neurological syndromes (PNS) and urothelial carcinoma – A review of the literature	24
Epigenetic modulation of the tumor microenvironment in head and neck cancer: Challenges and opportunities	24

Salvage radiotherapy after initial cryotherapy for localized prostate cancer: A systematic review of the literature	24
The use of bolus in postmastectomy radiation therapy for breast cancer: A systematic review	24
Comprehensive review of signaling pathways and therapeutic targets in gastrointestinal cancers	24
Editorial Board	24
Role of radiation in chimeric antigen receptor T-cell therapy for patients with relapsed/refractory non-Hodgkin lymphoma: Current studies and future prospects	23
Decoding the puzzle: A multidisciplinary systematic review of adult brainstem glioma	23
Safety and efficacy of liposomal irinotecan as the second-line treatment for advanced pancreatic cancer: A systematic review and meta-analysis	23
Cardio-oncology concerns in radiotherapy: Heart and cardiac substructure toxicities from modern delivery techniques	23
Surgical treatment of gastric cancer liver metastases: Systematic review and meta-analysis of long-term outcomes and prognostic factors	23
Neurotoxicities of novel non-steroidal anti-androgens for prostate cancer: A systematic review and meta-analysis	22
Prognostic and therapeutic value of somatic mutations in diffuse large B-cell lymphoma: A systematic review	22
Novel Methods of Risk Stratifying Patients for Metachronous, Pre-Malignant Colorectal Polyps: A Systematic Review	22
Recent advances and research progress in biomarkers for chronic graft versus host disease	22
« Augmented radiotherapy » in the management of high-risk prostate cancer (PCa): A systematic review	22
Drug-based therapy for advanced adenoid cystic carcinoma: Current landscape and challenges based on an overview of registered clinical trials	22
Epigenetic-modifying agents: The potential game changers in the treatment of hematologic malignancies	22
Systematic review of tumour budding and association with common mutations in patients with colorectal cancer	22
Rethinking treatment paradigms: Neoadjuvant therapy and de-escalation strategies in HPV-positive head and neck cancer	22
C-reactive protein as a diagnostic and prognostic factor of endometrial cancer	22
Receptor status of breast cancer diagnosed during pregnancy: A literature review	22
Personalized medicine for metastatic prostate cancer: The paradigm of PARP inhibitors	21
Editorial Board	21
Revolutionizing Immunotherapy: The Next Frontier in CAR T-Cell Engineering	21
The relationship between LDH and GLIM criteria for cancer cachexia: Systematic review and meta-analysis	21
Can the tumor-agnostic evaluation of MSI/MMR status be the common denominator for the immunotherapy treatment of patients with several solid tumors?	21
Artificial intelligence: A promising frontier in bladder cancer diagnosis and outcome prediction	21
Androgen annihilation versus advanced androgen blockage as first line treatment for metastatic castration resistant prostate cancer: A systematic review and meta-analysis	21
Long-term strategies for management of advanced basal cell carcinoma with hedgehog inhibitors	21
Circular RNAs as key regulators in cancer hallmarks: New progress and therapeutic opportunities	20
Progress in research: Daratumumab improves treatment outcomes of patients with AL amyloidosis	20
Effectiveness of photobiomodulation therapy in radiation dermatitis: A systematic review and meta-analysis	20
Association between bevacizumab with cancer drug therapies and drug-induced interstitial lung disease in patients with solid tumor: A systematic review and meta-analysis of randomized clinical trials	20
Clonal hematopoiesis of indeterminate potential (CHIP): A potential contributor to lymphoma	20
Endometrial cancer in the elderly: Characteristics, prognostic and risk factors, and treatment options	20
Navigating chemotherapy and immunotherapy in early-stage lung cancer. A critical review and statements from INTERACTION group	20
Immune checkpoint inhibitors as a threat to reproductive function: A systematic review	20
Testicular germ cell tumors: Genomic alternations and RAS-dependent signaling	20
A scoping review to map the evidence of physical activity interventions in post-treatment adolescent and young adult cancer survivors	20
Molecular oncology of iodine refractory thyroid cancer current therapies and perspective	19
Delta-like ligand 3 in small cell lung cancer: Potential mechanism and treatment progress	19
The crosstalk of the human microbiome in breast and colon cancer: A metabolomics analysis	19
Rare histotypes of epithelial biliary tract tumors: A literature review	19
The diagnostic accuracy of single-item scales in detecting fatigue in patients with cancer: A systematic review and meta-analysis	19
The impact of survivorship bias in glioblastoma research	19
Evaluation of clinical decision support systems in oncology: An updated systematic review	19
Radiotherapy of high-grade gliomas: dealing with a stalemate	19
Incidence of antibody–drug conjugates-related pneumonitis in patients with solid tumors: A systematic review and meta-analysis	18
Deciphering the possible reciprocal loop between hepatic stellate cells and cancer cells in the tumor microenvironment of the liver	18
Editorial Board	18
Combine radiotherapy and immunotherapy in esophageal squamous cell carcinoma	18
Molecular mechanisms of ferroptosis and its role in prostate cancer therapy	18
Uncovering the bookshelves of CRISPR-based libraries: Advances and applications in cancer studies	18
N6-methyladenosine-dependent signaling in colorectal cancer: Functions and clinical potential	18
Prospects of targeting PI3K/AKT/mTOR pathway in pancreatic cancer	18
Targeting breast cancer stem cells through retinoids: A new hope for treatment	18
Outcome after treatment with axitinib in children, young adults, and adults with renal cell carcinoma: a narrative review	17
Targeting the DNA damage response: PARP inhibitors and new perspectives in the landscape of cancer treatment	17
Profile of treatment-related adverse events of PD-1 blockade-based therapies in advanced esophageal cancer: A systematic review and meta-analysis	17
The application of stepped-wedge cluster-randomized controlled trial study designs in oncology settings: A systematic review	17
The effect of COVID-19 pandemic on daily oncology clinical practice	17
Effect of non-pharmacological interventions on symptoms and quality of life in patients with hematological malignancies – A systematic review	17
The educational contribution of the college of the European school of oncology (ESCO): A survey analysis of the first three years	17
Stereotactic body radiotherapy boost as an alternative to brachytherapy for cervical cancer: A scoping review	17
Editorial Board	17
Status of breast cancer in Latin American: Results of the breast cancer revealed initiative	17
Management of patients with extensive small-cell lung cancer in the immunotherapy era: An Italian consensus through a Delphi approach	16
A neuroendocrine biomarker revolution from monoanalyte to multianalyte biomarkers in non-functioning gastro-entero-pancreatic neuroendocrine neoplasms	16
Tyrosine kinase inhibitors in cancers: Treatment optimization – Part I	16
Spatial transcriptomics in pancreatic cancer: Advances, prospects and challenges	16
Venous thromboembolism in cancer and cancer immunotherapy	16
Evidence-based recommendations for induction and maintenance treatment of newly diagnosed transplant-ineligible multiple myeloma patients	16
Gamma Knife radiosurgery as primary treatment of low-grade brainstem gliomas: A systematic review and metanalysis of current evidence and predictive factors	15
Metaplastic breast cancer: A review	15
Chimeric antigen receptor T cell immunotherapy for gynecological malignancies	15
Protective effects of physical activity in colon cancer and underlying mechanisms: A review of epidemiological and biological evidence	15
Somatic and germline ATM variants in non-small-cell lung cancer: Therapeutic implications	15
Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategies	15
KRAS G12C-mutant driven non-small cell lung cancer (NSCLC)	15
CD200 expression in hematopoietic neoplasms: Beyond a marker for diagnosis of B-cell neoplasms	15
Significance of HOXD transcription factors family in progression, migration and angiogenesis of cancer	15

Which is the best treatment for melanoma brain metastases? A Bayesian network meta-analysis and systematic review	15
Epidermal growth factor receptor exon 20 insertion variants in non-small cell lung cancer patients	15
Standardized molecular pathology workflow for ctDNA-based ESR1 testing in HR+/HER2- metastatic breast cancer	15
Neoadjuvant endocrine therapy for luminal breast tumors: State of the art, challenges and future perspectives	15
COVID-19 and immunothrombosis: Pathophysiology and therapeutic implications	15
Expanding horizons in cancer therapy by immunoconjugates targeting tumor microenvironments	15
The study of primary and acquired resistance to first-line osimertinib to improve the outcome of EGFR-mutated advanced Non-small cell lung cancer patients: the challenge is open for new therapeutic st	15
The current landscape of systemic therapy for recurrent glioblastoma: A systematic review of randomized-controlled trials	15
Dynamic crosstalk within the tumor microenvironment of uterine cervical carcinoma: baseline network, iatrogenic alterations, and translational implications	15
The impact of PARP inhibitors in the whole scenario of ovarian cancer management: A systematic review and network meta-analysis	15
Application of molecular imaging in immune checkpoints therapy: From response assessment to prognosis prediction	14
KRAS mutations in advanced non-small cell lung cancer: From biology to novel therapeutic strategies	14
Comment on “A systematic review and meta-analysis of PD-1/PD-L1 inhibitors in specific patient subgroups with advanced gastro-oesophageal junction and gastric adenocarcinoma”	14
The application of cancer stem cell model in malignant mesothelioma	14
DNA methylation in oral squamous cell carcinoma: from its role in carcinogenesis to potential inhibitor drugs	14
Hematopoietic stem cell stretches and moves in its bone marrow niche	14
International consensus on the initial diagnostic workup of cancer of unknown primary	14
HER2-targeted therapies: Unraveling their role in biliary tract cancers	14
The impact of gender on The efficacy of immune checkpoint inhibitors in cancer patients: The MOUSEION-01 study	14
Belgian expert consensus for tumor-agnostic treatment of NTRK gene fusion-driven solid tumors with larotrectinib	14
Editorial Board	14
Advancing patient setup: A comprehensive scoping review of tattoo-less techniques in radiation therapy	14
Epigenetics in advanced renal cell carcinoma: Potential new targets	13
Patients’ selection and trial matching in early-phase oncology clinical trials	13
Diagnosis and treatment of therapy-related acute myeloid leukemia	13
Head and neck squamous cell carcinoma: Exploring frontiers of combinatorial approaches with tyrosine kinase inhibitors and immune checkpoint therapy	13
Clinical implications of the Drug-Drug Interaction in Cancer Patients treated with innovative oncological treatments	13
Liquid biopsy and preclinical tools for advancing diagnosis and treatment of patients with pancreatic neuroendocrine neoplasms	13
Editorial Board	13
Factors for a broad technology assessment of comprehensive genomic profiling in advanced cancer, a systematic review	13
Clonal hematopoiesis and inflammation: A review of mechanisms and clinical implications	13
The prevalence of solid tumors and hematologic malignancies among patients with Down syndrome: A systematic review and meta-analysis	13
Small cell lung cancer unveiled: Exploring the untapped resource of circulating tumor cells-derived organoids	13
Optimizing CDK4/6 inhibitors in advanced HR+/HER2- breast cancer: A personalized approach	13
Live European School of Oncology e-Sessions (e-ESO)	13
Real-world insights into the efficacy and safety of tyrosine kinase inhibitors against thyroid cancers	13
Relationship between purinergic signalling and oxidative stress in prostate cancer: Perspectives for future therapy	13
Is antibody-drug conjugate a rising star for clinical treatment of solid tumors? A systematic review and meta-analysis	13
Unlocking the intricacies: Exploring the complex interplay between platelets and ovarian cancer	13
How safe and effective is irradiating radiation-induced meningiomas? Single-center experience in primary and salvage Gamma-Knife Radiosurgery, systematic review, and metanalysis of current evidence on	13
Long non-coding RNA and the tumor microenvironment: Prospects for clinical applications in breast cancer	13
Perioperative imaging predictors of tumor progression and pseudoprogression: A systematic review	13
Supportive interventions for childhood cancer: An umbrella review of randomized evidence	12
The potential of circulating cell-free RNA in CNS tumor diagnosis and monitoring: A liquid biopsy approach	12
Warming-up the immune cell engagers (ICEs) era in breast cancer: state of the art and future directions	12
Bladder-sparing treatment for muscle-invasive bladder carcinoma using immune checkpoint inhibitors	12
Potential cytochrome P450-mediated pharmacokinetic interactions between herbs, food, and dietary supplements and cancer treatments	12
Advancements in tumor-infiltrating lymphocytes: Historical insights, contemporary milestones, and future directions in oncology therapy	12
Corrigendum to “The emerging HER2 landscape in Colorectal Cancer: The key to unveil the future treatment algorithm?” [Crit. Rev. Oncol./Hematol. 204 (2024) 104515]	12
Cellular senescence in tumor immune escape: Mechanisms, implications, and therapeutic potential	12
Surrogate endpoints in phase III randomized trials of advanced gastroesophageal cancer: A systematic review and meta-analysis	12
Prediction performance of twelve tumor mutation burden panels in melanoma and non-small cell lung cancer	12
The diverse molecular profiles of lynch syndrome-associated colorectal cancers are (highly) dependent on underlying germline mismatch repair mutations	12
Safety of immune checkpoint inhibitors: An updated comprehensive disproportionality analysis and meta-analysis	12
HER2-low breast cancer: Novel detections and treatment advances	12
The integration of radiotherapy with systemic therapy in advanced triple-negative breast cancer	12
Differentiation therapy: Unlocking phenotypic plasticity of hepatocellular carcinoma	12
Which treatment after first line therapy in NSCLC patients without genetic alterations in the era of immunotherapy?	12
Managing side effects of immune checkpoint inhibitors in breast cancer	12
Key considerations for a prostate cancer mRNA vaccine	12
Advanced and recurrent endometrial cancer: State of the art and future perspectives	12
Clinical and molecular overview of immunotherapeutic approaches for malignant skin melanoma: Past, present and future	11
Efficacy and safety of adjuvant chemotherapy for locally advanced cervical cancer: A systematic review and meta-analysis	11
Pseudoprogression in lung cancer patients treated with immunotherapy	11
Physical activity for cancer prehabilitation: A scoping review	11
Clinical applications of radiomics and deep learning in breast and lung cancer: A narrative literature review on current evidence and future perspectives	11
Effectiveness of different treatment strategies in elderly patients with glioblastoma: An evidence map of randomized controlled trials	11
Practical treatment guidance for cancer-associated thrombosis – Managing the challenging patient: A consensus statement	11
Molecular features and clinical actionability of gene fusions in colorectal cancer	11
Alternative polyadenylation in cancer: Molecular mechanisms and clinical application	11
Addition of immunotherapy to chemotherapy for metastatic triple-negative breast cancer: A systematic review and meta-analysis of randomized clinical trials	11
The potential targeted drugs for fusion genes including NRG1 in pancreatic cancer	11
Personalized medicine in oral cancer	11
Obesity and prostate cancer: A narrative review	11
Systemic treatment for hormone receptor-positive/HER2-negative advanced/metastatic breast cancer: A review of European real-world evidence studies	11
The hematopoietic microenvironment of the fetal liver and transient abnormal myelopoiesis associated with Down syndrome: A review	11
Central nervous system (CNS) prophylaxis in antiCD20-CHOP treated DLBCL at intermediate to high risk for CNS relapse: A systematic review and meta-analysis	11
Prognostic and therapeutic potential of STAT3: Opportunities and challenges in targeting HPV-mediated cervical carcinogenesis	11
Spectrum and genotyping strategies of “dark” genetic matter in germline susceptibility genes of tumor syndromes	11
The effect of nutritional interventions in acute radiation-induced diarrhoea in patients with primary pelvic cancer: A systematic review	11
Current knowledge of immunosuppression as a risk factor for skin cancer development	11
Editorial Board	11
Emerge of colorectal cancer in Lynch syndrome despite colonoscopy surveillance: A challenge of hide and seek	11
RNA-binding proteins in breast cancer: Biological implications and therapeutic opportunities	11
Immune therapies of B-cell acute lymphoblastic leukaemia in children and adults	11
A systematic review of contemporary phase I trials in patients with lymphoma	11
Cost-effectiveness of first-line immunotherapy for advanced non-small cell lung cancer with different PD-L1 expression levels: A comprehensive overview	11
Recent therapeutic advances in urothelial carcinoma: A paradigm shift in disease management	10
The role of immune checkpoint inhibitors in the treatment sequence of advanced gastric or gastro-esophageal junction cancer: A systematic review and meta-analysis of randomized trials	10
Updated review on analysis of long non-coding RNAs as emerging diagnostic and therapeutic targets in prostate cancers	10
Prognostic role of cell-free DNA biomarkers in pancreatic adenocarcinoma: A systematic review and meta–analysis	10
Charged particle radiotherapy for thyroid cancer. A systematic review	10
Development of asciminib, a novel allosteric inhibitor of BCR-ABL1	10
Economic evaluations and health economic models of soft tissue sarcomas: Systematic literature review from a European and North American perspective	10
Adenoid Cystic Carcinoma from the salivary and lacrimal glands and the breast: Different clinical outcomes to the same tumor	10