OOIR: Observatory of International Research

Papers

(The H4-Index of Critical Reviews in Oncology Hematology is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Double agents in immunotherapy: Unmasking the role of antibody drug conjugates in immune checkpoint targeting	350
Editorial Board	224
Stereotactic body radiation therapy versus conventional external beam radiation therapy for painful bone metastases: A systematic review and meta-analysis of randomized trials	174
Total neoadjuvant treatment and organ preservation strategies in the management of localized rectal cancer: A narrative review and evidence-based algorithm	139
Letter to the Editor regarding the article “A net-work meta-analysis of the cardiac safety for next-generation hormonal agents in treating castration-resistant prostate cancer: How to choose drugs app	114
Skin barrier dysfunction in cutaneous T-cell lymphoma: From pathogenic mechanism of barrier damage to treatment	106
Comparative efficacy of first-line therapies for PD-L1-negative advanced NSCLC: A network meta-analysis with reconstructed survival curves	103
Open issues in the therapeutic management of unresectable stage III NSCLC in the immunotherapy era	82
Beyond the blood-brain barrier: Intranasal vaccines in cancer immunotherapy	80
The hidden hand of endoplasmic reticulum stress in anticancer drug resistance	76
Unveiling the Role of JAK2/STAT3 signaling in chemoresistance of gynecological cancers: From mechanisms to therapeutic implications	72
From immunohistochemistry to machine learning-based patient stratification by tumour proliferation characteristics in head and neck cancer	72
Targeted doublet therapy with encorafenib and cetuximab for BRAF V600E-mutant metastatic colorectal cancer: A systematic review and meta-analysis	63
Development of treatment strategies for advanced HER2-positive gastric cancer: Insights from clinical trials	62
Harnessing tumor metabolism during cancer treatment: A narrative review of emerging dietary approaches	60
Mapping the research landscape of HPV-positive oropharyngeal cancer: a bibliometric analysis	58
The BCL-2–tumor microenvironment axis: Mechanisms of immune suppression, resistance, and pathways to therapeutic reprogramming	58
Stereotactic body radiotherapy as an alternative to brachytherapy in cervical cancer (SCORE): A systematic review and meta-analysis	57
Novel bioengineered drugs with immunotherapies for malignant pleural effusion: Remodulate tumor immune microenvironment and activate immune system	55
When immunity backfires: Meta-analysis on sarcoidosis reactivation in cancer patients treated with immune checkpoint inhibitors	53
Dysregulation of systemic immunity in colorectal cancer and its clinical applications as biomarkers and therapeutics	53
Surface-Enhanced Raman Scattering (SERS) combined with machine learning enables accurate diagnosis of cervical cancer: From molecule to cell to tissue level	52
Microbiome and lung cancer: carcinogenic mechanisms, early cancer diagnosis, and promising microbial therapies	49
Efficacy of PD-1/PD-L1 immunotherapy on brain metastatic non-small-cell lung cancer and treatment-related adverse events: A systematic review	49
Systemic immune-inflammation index as a predictor of survival in non-small cell lung cancer patients undergoing immune checkpoint inhibition: A systematic review and meta-analysis	48

Apigenin in cancer prevention and therapy: A systematic review and meta-analysis of animal models	47
Tyrosine kinase inhibitors in cancers: Treatment optimization – Part II	46
Novel insight into the Warburg effect: Sweet temptation	43
Navigating management of localized prostate cancer in the geriatric population	43
Innovations in cancer immunotherapy: A comprehensive overview of recent breakthroughs and future directions	42
Direct and indirect effects on child neurocognitive development when maternal cancer is diagnosed during pregnancy: What do we know so far?	42
Bidirectional role of neutrophils in lung cancer: Mechanisms and therapeutic implications	41
A systematic review and meta-analysis of blood-based biomarkers in anal squamous cell cancer treated with chemoradiotherapy	41
Real-world analysis of primary central nervous system diffuse large B-cell lymphoma	41
Microbiome dynamics in breast cancer: Mechanisms, therapeutic impacts and research gaps	41
Advancing tumor vaccines: Overcoming TME challenges, delivery strategies, and biomaterial-based vaccine for enhanced immunotherapy	41
A non-invasive miRNA-based approach in early diagnosis and therapeutics of oral cancer	40
The role of cGAS-STING in remodeling the tumor immune microenvironment induced by radiotherapy	39
Spatial multiomics of the breast tumour microenvironment: State of the field, advancements and clinical implementation promises	39
Current status of locally advanced rectal cancer therapy and future prospects	39
Beyond monospecificity: The modular revolution of bispecific immunotherapeutics	39