OOIR: Observatory of International Research

Papers

(The TQCC of Critical Reviews in Clinical Laboratory Sciences is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Data analytics for error detection in clinical laboratories	69
Lipoprotein(a): a genetically determined risk factor for Cardiovascular disease	62
The dual roles of microorganisms in inflammatory diseases: initiators and regulators	55
The anion gap as a predictive tool for morbidity and mortality	52
Aptamer-based biosensing strategies for influenza virus detection: a systematic and critical review of electrochemical and optical platforms	52
Deep learning algorithms and Raman spectroscopy in the clinical laboratory setting	39
Advances and challenges in the measurement of 1,25-dihydroxyvitamin D: a comprehensive review	38
Machine learning-based error detection in the clinical laboratory: a critical review	35
Human telomere length detected by quantitative fluorescent in situ hybridization: overlooked importance and application	34
Single cell mechanodeformation signatures as early biomarkers for hematological malignancies	33
Copeptin as a surrogate marker for arginine vasopressin: analytical insights, current utility, and emerging applications	30
Transthyretin mutagenesis: impact on amyloidogenesis and disease	28
Clinical utility of human epididymis protein 4	27
Comparison of liquid biopsy-based technologies for cancer screening	26
The therapeutic relevance of the Kallikrein-Kinin axis in SARS-cov-2-induced vascular pathology	26
Beyond newborn screening: the role of reverse cascade testing in familial disease detection	24
Cardiovascular disease lipids and lipoproteins biomarker standardization	23
Indirect methods for the verification of reference intervals in laboratory medicine	23
Guidance for securing approvals for new biomarkers: from discovery to clinical implementation	23
Mid-regional pro-atrial natriuretic peptide in managing cardiovascular and cerebrovascular diseases	22
KIF2C/MCAK a prognostic biomarker and its oncogenic potential in malignant progression, and prognosis of cancer patients: a systematic review and meta-analysis as biomarker	22
Development of next-generation reference interval models to establish reference intervals based on medical data: current status, algorithms and future consideration	21
One health and laboratory medicine: challenges and perspectives for antimicrobial resistance, emerging infections, and food/water security	21
Blood biomarkers for the diagnosis of chorioamnionitis following preterm premature rupture of membranes: a systematic review and meta-analysis of studies since 2020	19
It’s in the blood: a review of the hematological system in SARS-CoV-2-associated COVID-19	19

Challenges of insulin-like growth factor-1 testing	17
Omics-based computational approaches for biomarker identification, prediction, and treatment of Long COVID	17
Analytical and clinical considerations of synovial fluid calprotectin in diagnosing periprosthetic joint infections	16
Association of inflammatory biomarkers with morbidity and mortality risk in patients with peripheral artery disease: a systematic review and meta-analysis	16
Stage-specific circulating transcriptomic and proteomic biomarkers and regulators in colorectal cancer: bridging affordable diagnostics and translational therapeutics	16
Emerging applications of machine learning in genomic medicine and healthcare	15
The intersection of the laboratory and transgender care	14
Pleural fluid biomarkers for the diagnosis and management of malignant pleural effusions: a clinical review	13
Therapeutic biomarkers in metastatic castration-resistant prostate cancer: does the state matter?	13
Methodological and conceptual challenges to the flow cytometric classification of leukemic lymphoproliferative disorders	12
Insight into metabolic dysregulation of polycystic ovary syndrome utilizing metabolomic signatures: a narrative review	12
General features, pathogenesis, and laboratory diagnostics of autoimmune encephalitis	12
Guidelines for diagnosing and differentiating infection with antifungal-resistant Trichophyton indotineae from other dermatophytoses	12
Circulating tumor DNA (ctDNA): can it be used as a pan-cancer early detection test?	12
Diagnostic stewardship monitoring systems: institutional and system-level approaches	12
Glycation and disease: a systematic review of the analytical methods and applications of advanced glycation end products (AGEs) as biomarkers of disease	12