OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Clinical Laboratory Sciences is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
The COVID-19 pandemic	696
Biomarkers associated with COVID-19 disease progression	506
COVID-19: from an acute to chronic disease? Potential long-term health consequences	206
Current concepts and advances in biomarkers of acute kidney injury	71
The COVID-19 pandemic: viral variants and vaccine efficacy	60
Effects of age, sex, serostatus, and underlying comorbidities on humoral response post-SARS-CoV-2 Pfizer-BioNTech mRNA vaccination: a systematic review	53
A summary of the diagnostic and prognostic value of hemocytometry markers in COVID-19 patients	50
Vitamin B₁₂status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls	49
Preanalytical variables that affect the outcome of cell-free DNA measurements	48
Potential value and impact of data mining and machine learning in clinical diagnostics	45
Vitamin D: sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its metabolites	43
Molecular diagnostic assays for COVID-19: an overview	41
The laboratory’s role in combating COVID-19	36
Recent evolutions of machine learning applications in clinical laboratory medicine	25
Immunoscore: a novel prognostic tool. Association with clinical outcome, response to treatment and survival in several malignancies	21
Implementation of patient-based real-time quality control	20
Perspectives on the role of PTEN in diabetic nephropathy: an update	20
The molecular structure and biological functions of RNA methylation, with special emphasis on the roles of RNA methylation in autoimmune diseases	20
Molecular tissue profiling by MALDI imaging: recent progress and applications in cancer research	20
Breathing new life into clinical testing and diagnostics: perspectives on volatile biomarkers from breath	19
Liquid biopsy with cell free DNA: new horizons for prostate cancer	19
Nucleic acid-based electrochemical biosensors for rapid clinical diagnosis: advances, challenges, and opportunities	18
Procalcitonin for individualizing antibiotic treatment: an update with a focus on COVID-19	18
What the lab can and cannot do: clinical interpretation of drug testing results	17
The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function and overall outcome	17

T helper cells in depression: central role of Th17 cells	17
The role of kallikreins in inflammatory skin disorders and their potential as therapeutic targets	16
Oligoclonal bands: clinical utility and interpretation cues	15
CRISPR-based biosensing systems: a way to rapidly diagnose COVID-19	14
Clinical applications of extracellular vesicle long RNAs	14
Multiple biomarker approach for the diagnosis and therapy of rheumatoid arthritis	14
Immunologic evaluation and genetic defects of apoptosis in patients with autoimmune lymphoproliferative syndrome (ALPS)	14
Choice of SARS-CoV-2 diagnostic test: challenges and key considerations for the future	14
Methods for detecting toxic α-synuclein species as a biomarker for Parkinson’s disease	13
Quantifying RNA modifications by mass spectrometry: a novel source of biomarkers in oncology	13
The potential impact of salivary peptides in periodontitis	13
Progress in understanding COVID-19: insights from the omics approach	12
Systematic review and meta-analysis of C-reactive protein as a biomarker in breast cancer	12
Smartphone technology facilitates point-of-care nucleic acid diagnosis: a beginner’s guide	12
Identifying and overcoming barriers to harmonize newborn screening programs through consensus strategies	11
DropWise: current role and future perspectives of dried blood spots (DBS), blood microsampling, and their analysis in sports drug testing	11
The clinical and laboratory investigation of dysbetalipoproteinemia	11
Presentation and formatting of laboratory results: a narrative review on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group “postanalytical phase” (WG	11
Clinical utility of procalcitonin and its association with pathogenic microorganisms	10
Lean and Six Sigma as continuous quality improvement frameworks in the clinical diagnostic laboratory	10
Disruptive innovations in the clinical laboratory: catching the wave of precision diagnostics	8
Impact of body mass index on growth hormone stimulation tests in children and adolescents: a systematic review and meta-analysis	8
Personalized reference intervals: from theory to practice	8
Evaluation of pathophysiological relationships between renin-angiotensin and ACE-ACE2 systems in cardiovascular disorders: from theory to routine clinical practice in patients with heart failure	8
Evidence-based approach to setting delta check rules	8
Novel biomarkers in Alzheimer’s disease using high resolution proteomics and metabolomics: miRNAS, proteins and metabolites	7
Biomarkers of disease in human nails: a comprehensive review	6
Physiological and metabolic adaptations in pregnancy: importance of trimester-specific reference intervals to investigate maternal health and complications	6
Free thyroxine measurement in clinical practice: how to optimize indications, analytical procedures, and interpretation criteria while waiting for global standardization	6
Cardiovascular benefit of SGLT2 inhibitors	6
Clot activators and anticoagulant additives for blood collection. A critical review on behalf of COLABIOCLI WG-PRE-LATAM	6
Metabolomics of asthma, COPD, and asthma-COPD overlap: an overview	6
Development of circulating microRNA-based biomarkers for medical decision-making: a friendly reminder of what should NOT be done	6
Evaluating thyroid function in pregnant women	6
Current understanding and controversies on the clinical implications of fibroblast growth factor 21	6
Screening and diagnosis of inherited platelet disorders	6
Clinical features and diagnostic tools in idiopathic inflammatory myopathies	5
Overutilization in laboratory medicine: tackling the problem with quality improvement science	5
Bone health and hyperglycemia in pediatric populations	5
Immunohistochemistry features and molecular pathology of appendiceal neoplasms	5
Essential role of laboratory physicians in transformation of laboratory practice and management to a value-based patient-centric model	5
Current status and challenges in establishing reference intervals based on real-world data	4
Complement testing in the clinical laboratory	4
Pre-analytical conditions and implementation of quality control steps in liquid biopsy analysis	4
Using a systematic approach to strategic innovation in laboratory medicine to bring about change	4
Oxidized LDL-regulated microRNAs for evaluating vascular endothelial function: molecular mechanisms and potential biomarker roles in atherosclerosis	4
The genomic and biological complexity of mixed phenotype acute leukemia	4