OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Clinical Laboratory Sciences is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-03-01 to 2025-03-01.)

Article	Citations
It’s in the blood: a review of the hematological system in SARS-CoV-2-associated COVID-19	79
Unlocking the link between haptoglobin polymorphism and noninfectious human diseases: insights and implications	78
Advances and challenges in the measurement of 1,25-dihydroxyvitamin D: a comprehensive review	75
Physiological and metabolic adaptations in pregnancy: importance of trimester-specific reference intervals to investigate maternal health and complications	66
Molecular effects of ozone on amino acids and proteins, especially human hemoglobin and albumin, and the need to personalize ozone concentration in major ozone autohemotherapy	64
Lipoprotein(a): a genetically determined risk factor for Cardiovascular disease	35
Preterm labor tests: current status and future directions	31
Challenges of insulin-like growth factor-1 testing	27
The European Organisation of External Quality Assurance Providers in Laboratory Medicine (EQALM) Statement: guidelines for publishing about interlaboratory comparison studies (PubILC)	27
A review of clinical guidelines, laboratory recommendations and external quality assurance programs for monoclonal gammopathy testing	22
The molecular structure and biological functions of RNA methylation, with special emphasis on the roles of RNA methylation in autoimmune diseases	21
Genotype-phenotype correlation in the spectrum of frontotemporal dementia-parkinsonian syndromes and advanced diagnostic approaches	21
Liquid biopsy for the management of NSCLC patients under osimertinib treatment	21
G protein-coupled receptor (GPCR) pharmacogenomics	21
Research progress of KL-6 in respiratory system diseases	21
Vitamin B₁₂status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls	20
Breathing new life into clinical testing and diagnostics: perspectives on volatile biomarkers from breath	19
Potential value and impact of data mining and machine learning in clinical diagnostics	19
Omics-based novel strategies in the diagnosis of endometriosis	17
The role of immunophenotyping in common variable immunodeficiency: a narrative review	16
Genetic variants of accessory proteins and G proteins in human genetic disease	15
Using a systematic approach to strategic innovation in laboratory medicine to bring about change	13
Impact of body mass index on growth hormone stimulation tests in children and adolescents: a systematic review and meta-analysis	12
The elusive male microbiome: revealing the link between the genital microbiota and fertility. Critical review and future perspectives	12
Lipid-binding antiphospholipid antibodies: significance for pathophysiology and diagnosis of the antiphospholipid syndrome	11

Current status in cellular-based therapies for prevention and treatment of COVID-19	11
Lean and Six Sigma as continuous quality improvement frameworks in the clinical diagnostic laboratory	11
G protein-coupled receptor (GPCR) gene variants and human genetic disease	11
Overutilization in laboratory medicine: tackling the problem with quality improvement science	11
Design, optimization, and application of multiplex rRT-PCR in the detection of respiratory viruses	11
Reference intervals: past, present, and future	11
Technical quality assurance and quality control for medical laboratories: a review and proposal of a new concept to obtain integrated and validated QA/QC plans	10
Emerging applications of machine learning in genomic medicine and healthcare	10
Procalcitonin for individualizing antibiotic treatment: an update with a focus on COVID-19	10
Copeptin as a surrogate marker for arginine vasopressin: analytical insights, current utility, and emerging applications	9
Correction	8
The significance of antigen-antibody-binding avidity in clinical diagnosis	8
Analytical and clinical considerations of synovial fluid calprotectin in diagnosing periprosthetic joint infections	8
Transthyretin mutagenesis: impact on amyloidogenesis and disease	7
Current and emerging technologies for the timely screening and diagnosis of neonatal jaundice	7
Choice of SARS-CoV-2 diagnostic test: challenges and key considerations for the future	7
Clinical utility of procalcitonin and its association with pathogenic microorganisms	7
Human telomere length detected by quantitative fluorescent in situ hybridization: overlooked importance and application	7
DropWise: current role and future perspectives of dried blood spots (DBS), blood microsampling, and their analysis in sports drug testing	7
Revisiting approaches to and considerations for urinalysis and urine culture reflexive testing	7
Von Willebrand factor and disease: a review for laboratory professionals	6
Newborn screening of mucopolysaccharidosis type I	6
New biomarkers in acute kidney injury	5
Vitamin D: sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its metabolites	5
Laboratory biomarkers in the diagnosis and follow-up of treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis	5
Oligoclonal bands: clinical utility and interpretation cues	5
Biomarkers of disease in human nails: a comprehensive review	5
Managing biological variation data: modern approaches for study design and clinical application	5
Artificial intelligence in serum protein electrophoresis: history, state of the art, and perspective	4
Personalized reference intervals: from theory to practice	4
The therapeutic relevance of the Kallikrein-Kinin axis in SARS-cov-2-induced vascular pathology	4
Estimating glomerular filtration rate with new equations: can one size ever fit all?	4
Therapeutic biomarkers in metastatic castration-resistant prostate cancer: does the state matter?	4
Extracellular vesicles in cancer: challenges and opportunities for clinical laboratories	4
Nucleic acid-based electrochemical biosensors for rapid clinical diagnosis: advances, challenges, and opportunities	4
Evaluating thyroid function in pregnant women	4
Complement testing in the clinical laboratory	4
Mapping of audiometric analysis with microbiological findings in patients with chronic suppurative otitis media (CSOM): a neglected clinical manifestation	4
The role of the clinical laboratory in diagnosing hyponatremia disorders	3
General features, pathogenesis, and laboratory diagnostics of autoimmune encephalitis	3
Pre-analytical conditions and implementation of quality control steps in liquid biopsy analysis	3
Developing an SI-traceable Lp(a) reference measurement system: a pilgrimage to selective and accurate apo(a) quantification	3
Analytical performance specifications and quality assurance of point-of-care testing in primary healthcare	3
The role of bile acid metabolism in bone and muscle: from analytics to mechanisms	3
Inherited causes of exocrine pancreatic insufficiency in pediatric patients: clinical presentation and laboratory testing	3
Optimizing the data in direct access testing: information technology to support an emerging care model	3