American Journal of Physiology-Lung Cellular and Molecular Physiology

Article	Citations
Endothelial knockdown of the tumor suppressor, WWOX, increases inflammation in ventilator-induced lung injury	100
Simple model of pulmonary hypertension secondary to left heart pressure overload induced by partial intravascular occlusion of the ascending aorta	88
Feeling good: welcoming the new editorial team for American Journal of Physiology-Lung Cellular and Molecular Physiology	52
Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma	51
ARDS in the time of corona: context and perspective	48
Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation	44
Increased exploration and hyperlocomotion in a cigarette smoke and LPS-induced murine model of COPD: linking pulmonary and systemic inflammation with the brain	42
Genes, other than Muc5b, play a role in bleomycin-induced lung fibrosis	41
PTPα promotes fibroproliferative responses after acute lung injury	39
Metabolic signatures of ARDS and ARDS heterogeneity	36
Early extubation to noninvasive respiratory support of former preterm lambs improves long-term respiratory outcomes	36
A personal appreciation of Mary Ellen Avery for World Prematurity Day	34
Oxidized phosphatidylcholines induce multiple functional defects in airway epithelial cells	32
Reply to Vogel et al.	32
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease	31
Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection	30
COPD susceptibility gene HHIP regulates repair genes in airway epithelial cells and repair within the epithelial-mesenchymal trophic unit	29
Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation	28
Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced bySaccharopolyspora rectivirgula	27
Rat bronchoalveolar lavage proteome changes following e-cigarette aerosol exposures	26
FGF18 promotes human lung branching morphogenesis through regulating mesenchymal progenitor cells	26
A preclinical systematic review and meta-analysis assessing the effect of biological sex in lipopolysaccharide-induced acute lung injury	26
A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage	25
PINK1 mediates the protective effects of thyroid hormone T3 in hyperoxia-induced lung injury	25
CFTR as a therapeutic target for severe lung infection	25

A neutrophil subset defined by intracellular olfactomedin 4 is associated with mortality in sepsis	25
Lung disease manifestations in Down syndrome	25
Dynamic driving pressure predicts ventilator-induced lung injury in mice with and without endotoxin-induced acute lung injury	24
Integral assessment of gas exchange during veno-arterial ECMO: accuracy and precision of a modified Fick principle in a porcine model	23
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension	23
Role of transient receptor potential vanilloid 4 in therapeutic antifibrotic effects of pirfenidone	22
Role of STIM1 in stretch-induced signaling in human airway smooth muscle	22
Exhaled breath condensate identifies metabolic dysregulation in patients with radiation-induced lung injury	22
Cross talk between LAM cells and fibroblasts may influence alveolar epithelial cell behavior in lymphangioleiomyomatosis	22
Activation of platelets and the complement system in mice with Schistosoma-induced pulmonary hypertension	22
Biomarkers of alveolar epithelial injury and endothelial dysfunction are associated with scores of pulmonary edema in invasively ventilated patients	22
Dysregulation of ion transport in the lung epithelium infected with SARS-CoV-2	22
Call for Papers: “Alveolar biology, pulmonary surfactant, and beyond”: a tribute to Dr. John Allen Clements on his 100th birthday	21
Passive siRNA transfection method for gene knockdown in air-liquid interface airway epithelial cell cultures	21
β-Ionone facilitates ex vivo airway smooth muscle relaxation via extraocular opsin-3 light receptor activation	20
FGF2 is secreted in extracellular vesicles from lung cells	20
Role of voltage-gated Ca2+ channels and Ano1 Ca2+-activated Cl− channels in M2 muscarinic receptor-dependent contractions of murine airway smooth muscle	20
T-cell dysregulation and inflammatory process in Gcn2 (Eif2ak4−/−)-deficient rats in basal and stress conditions	20
Exercise-induced alterations in phospholipid hydrolysis, airway surfactant, and eicosanoids and their role in airway hyperresponsiveness in asthma	20
Nicotinic receptors in airway disease	19
Disease-specific platelet signaling defects in idiopathic pulmonary arterial hypertension	19
Increased serum SP-D in identification of high-risk smokers at high risk of COPD	19
Effects of glial-derived neurotrophic factor on remodeling and mitochondrial function in human airway smooth muscle cells	19
Inflammatory and antiviral responses to influenza A virus infection are dysregulated in pregnant mice with allergic airway disease	19
Standardization of methods for sampling the distal airspace in mechanically ventilated patients using heat moisture exchange filter fluid	18
IL-17A neutralization fails to attenuate airway remodeling and potentiates a proinflammatory lung microenvironment in diacetyl-exposed rats	18
The effect of adrenalectomy on bleomycin-induced pulmonary fibrosis in mice	18
An American Physiological Society cross-journal Call for Papers on “Inter-Organ Communication in Homeostasis and Disease”	18
A comprehensive map of proteoglycan expression and deposition in the pulmonary arterial wall in health and pulmonary hypertension	18
Endothelin-1 depletion of cartilage oligomeric matrix protein modulates pulmonary artery superoxide and iron metabolism-associated mitochondrial heme biosynthesis	18
A rapidly changing understanding of COPD: World COPD Day from the COPD Foundation	18
Systematic analysis of candidate reference genes for gene expression analysis in hyperoxia-based mouse models of bronchopulmonary dysplasia	17
ADAM10 partially protects mice against influenza pneumonia by suppressing specific myeloid cell population	17
Mouse lung organoid responses to reduced, increased, and cyclic stretch	17
Cellular senescence is increased in airway smooth muscle cells of elderly persons with asthma	17
World health day observances in November 2021: advocating for adult and pediatric pneumonia, preterm birth, and chronic obstructive pulmonary disease	17
SM22α cell-specific HIF stabilization mitigates hyperoxia-induced neonatal lung injury	17
Living with lung disease: experimental models to assess the long-term effects of prematurity	17
A primate-specific RNA-binding protein (RBMXL3) is involved in glucocorticoid regulation of human pulmonary surfactant protein B (SP-B) mRNA stability	17
Role of ZIP kinase in development of myofibroblast differentiation from HPMCs	17
Abrogation of mesenchyme-specific TGF-β signaling results in lung malformation with prenatal pulmonary cysts in mice	17
Good things: announcing the next round of the American Journal of Physiology-Lung Cellular and Molecular Physiology Editorial Board Fellowship Program	16
BMP4 and Wnt signaling interact to promote mouse tracheal mesenchyme morphogenesis	16
A new Anticalin protein for IL-23 inhibits non-type 2 allergen-driven mouse lung inflammation and airway hyperresponsiveness	16
Development of a peripheral blood transcriptomic gene signature to predict bronchopulmonary dysplasia	16
Circulating biomarker analyses in a longitudinal cohort of patients with IPF	16
Effect of physical activity in lymphocytes senescence burden in patients with COPD	16
Surfactant Protein-A and its immunomodulatory roles in infant respiratory syncytial virus infection: a potential for therapeutic intervention?	16
Epinephrine evokes shortening of human airway smooth muscle cells following β2adrenergic receptor desensitization	16
Cross-journal Call for Papers on “Opioids and Respiratory Depression”	16

M4 muscarinic receptors mediate acetylcholine-induced suppressant effects on the cough reflex in the caudal nucleus tractus solitarii of the rabbit	16
Mitochondrial ribosomal stress in lung diseases	16
Nicotine affects mitochondrial structure and function in human airway smooth muscle cells	15
Long-term survivors of murine sepsis are predisposed to enhanced LPS-induced lung injury and proinflammatory immune reprogramming	15
Pharmacological sphingosine-1 phosphate receptor 1 targeting in cigarette smoke-induced emphysema in mice	15
World AIDS Day 2021: highlighting the pulmonary complications of HIV/AIDS	15
Protective effects of neuropeptide Y against elastase-induced pulmonary emphysema	15
Pulmonary implications of acetaminophen exposures independent of hepatic toxicity	15
Acute vaping in a golden Syrian hamster causes inflammatory response transcriptomic changes	15
Stem cells, cell therapies, and bioengineering in lung biology and disease 2021	15
Molecular mechanisms of Na,K-ATPase dysregulation driving alveolar epithelial barrier failure in severe COVID-19	15
Altered lung metabolism and mitochondrial DAMPs in lung injury due to acute kidney injury	15
High-altitude pulmonary edema: the intercellular network hypothesis	14
Pathogenesis, clinical features of asthma COPD overlap, and therapeutic modalities	14
Menthol in electronic cigarettes causes biophysical inhibition of pulmonary surfactant	14
Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model for COPD: the lung-gut axis	14
Absolute quantification of plasma mitochondrial DNA by droplet digital PCR marks COVID-19 severity over time during intensive care unit admissions	14
Androgen receptor activation alleviates airway hyperresponsiveness, inflammation, and remodeling in a murine model of asthma	14
Contribution of transient receptor potential canonical channels in human and experimental pulmonary arterial hypertension	14
A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?	14
Short-chain fatty acids improve inflamm-aging and acute lung injury in old mice	14
Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-1	14
RSV attenuates epithelial cell restitution by inhibiting actin cytoskeleton-dependent cell migration	14
Looking at the developing lung in single-cell resolution	13
Analysis of the alveolar shape in 3-D	13
Targeted stereology: sampling heterogeneously distributed structures and lesions in the lung	13
Distinct types of plexiform lesions identified by synchrotron-based phase-contrast micro-CT	13
Peer Review Week, 2021	13
Endothelial metabolism in pulmonary vascular homeostasis and acute respiratory distress syndrome	13
Every breath you take: exploring macrophages and environmental exposures in the lung—a tribute to Dr. Joseph Brain’s legacy	13
The pontine Kölliker-Fuse nucleus is important for reduced postinspiratory airflow elicited by stimulation of the ventral respiratory parafacial region	13
cUMP elicits interendothelial gap formation during Pseudomonas aeruginosa infection	13
A new anesthesia protocol enabling longitudinal lung-function measurements in neonatal rabbits by micro-CT	13
Pulmonary-delivered Anticalin Jagged-1 antagonists reduce experimental airway mucus hyperproduction and obstruction	13
T cell and airway smooth muscle interaction: a key driver of asthmatic airway inflammation and remodeling	13
A toolbox for studying respiratory viral infections using air-liquid interface cultures of human airway epithelial cells	12
Culture conditions differentially regulate the inflammatory niche and cellular phenotype of tracheobronchial basal stem cells	12
Muscarinic receptors in the nucleus tractus solitarii	12
Sensitive physiological readouts to evaluate countermeasures for lipopolysaccharide-induced lung alterations in mice	12
Mitoquinone mesylate attenuates pathological features of lean and obese allergic asthma in mice	12
Constitutive transgenic α-Klotho overexpression enhances resilience to and recovery from murine acute lung injury	12
Understanding the role of placental pathophysiology in the development of bronchopulmonary dysplasia	12
Hyaluronan/CD44 axis regulates S100A4-mediated mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis	12
Exposure to carbon black nanoparticles during pregnancy aggravates lipopolysaccharide-induced lung injury in offspring: an intergenerational effect	12
Maternal diabetes promotes offspring lung dysfunction and inflammation in a sex-dependent manner	12
LL-37 and HMGB1 induce alveolar damage and reduce lung tissue regeneration via RAGE	12
Lung-kidney interactions and their role in chronic kidney disease-associated pulmonary diseases	12
Reply to Myslivecek	12
A wrinkle in time: circadian biology in pulmonary vascular health and disease	12
Differentiating children with sepsis with and without acute respiratory distress syndrome using proteomics	12
Racing against time: leveraging preclinical models to understand pulmonary susceptibility to perinatal acetaminophen exposures	12
Lack of a transcriptional response of primary bronchial epithelial cells from patients with asthma and controls to IL-33	11
Lysyl oxidase regulation and protein aldehydes in the injured newborn lung	11
Kidney-lung cross talk during ARDS: mitochondrial DAMPs join the conversation	11
Corrigendum for Audi et al., volume 323, 2022, p. L410–L422	11
RSV infection potentiates TRPV1-mediated calcium transport in bronchial epithelium of asthmatic children	11
Prolonged, physiologically relevant nicotine concentrations in the airways of smokers	11
The impact of nebulized epoprostenol and iloprost on hemoglobin oxygen affinity: an ex vivo experiment	11
Molecular insights using spatial transcriptomics of the distal lung in congenital diaphragmatic hernia	11
MK2 nonenzymatically promotes nuclear translocation of caspase-3 and resultant apoptosis	11
Congenital heart disease-associated pulmonary dysplasia and its underlying mechanisms	11
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa	11
Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions	11
Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension	11
Chronic hyperglycemia aggravates lung function in a Scnn1b-Tg murine model	11
LMTK2 switches on canonical TGF-β1 signaling in human bronchial epithelial cells	11
Enhanced epithelial sodium channel activity in neonatal Scnn1b mouse lung attenuates high oxygen-induced lung injury	11
Distribution, composition, and activity of airway-associated adipose tissue in the porcine lung	11
Lung pericytes as mediators of inflammation	11
Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis	11
Genetic deficiency of the transcription factor NFAT1 confers protection against fibrogenic responses independent of immune influx	11
Diacetyl inhalation impairs airway epithelial repair in mice infected with influenza A virus	11
Impaired antiviral immunity in frequent exacerbators of chronic obstructive pulmonary disease	11
Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2α	11
Inference of alveolar capillary network connectivity from blood flow dynamics	11
Human pulmonary microvascular endothelial cell DDAH1-mediated nitric oxide production promotes pulmonary smooth muscle cell apoptosis in co-culture	11
Obesity elicits a unique metabolomic signature in human airway smooth muscle cells	10
Metabolic profiling of in vivo right ventricular function and exercise performance in pulmonary arterial hypertension	10
Understanding potential mechanisms of harm: the drivers of electronic cigarette-induced changes in alveolar macrophages, neutrophils, and lung epithelial cells	10
Enhanced glycolysis causes extracellular acidification and activates acid-sensing ion channel 1a in hypoxic pulmonary hypertension	10

M2 macrophages have unique transcriptomes but conditioned media does not promote profibrotic responses in lung fibroblasts or alveolar epithelial cells in vitro	10
Involvement of ryanodine receptors in the contraction of small pulmonary veins	10
Investigating the role of platelets and platelet-derived transforming growth factor-β in idiopathic pulmonary fibrosis	10
Identification of FGFR4 as a regulator of myofibroblast differentiation in pulmonary fibrosis	10
Store-operated calcium entry-associated regulatory factor regulates airway inflammation and airway remodeling in asthma mice models	10
The matricellular protein CCN3 supports lung endothelial homeostasis and function	10
Red blood cells function as reservoirs of tumor DNA	10
Rho/ROCK-MYOCD in regulating airway smooth muscle growth and remodeling	10
Complex roles of TGF-β signaling pathways in lung development and bronchopulmonary dysplasia	10
Increased circulating cytokeratin 19 fragment levels in preterm neonates receiving mechanical ventilation are associated with poor outcome	10
Multicompartmental analysis of the murine pulmonary immune response by spectral flow cytometry	10
Identification of lung innervating sensory neurons and their target specificity	10
Geranylgeranyl diphosphate synthase deficiency hyperactivates macrophages and aggravates lipopolysaccharide-induced acute lung injury	10
The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions	10
A simple method to generate human airway epithelial organoids with externally orientated apical membranes	10
The effect of estrogen in coronavirus disease 2019	9
The differential roles of the two NO-GC isoforms in adjusting airway reactivity	9
Blocking ATP-releasing channels prevents high extracellular ATP levels and airway hyperreactivity in an asthmatic mouse model	9
Piezo channels modulate human lung fibroblast function	9
Early-life pulmonary viral infection leads to long-term functional and lower airway structural changes in the lungs	9
Multivalent, calcium-independent binding of surfactant protein A and D to sulfated glycosaminoglycans of the alveolar epithelial glycocalyx	9
In vivo molecular imaging stratifies rats with different susceptibilities to hyperoxic acute lung injury	9
Low global arginine bioavailability: a common phenomenon in pulmonary hypertension	9
Ivacaftor partially corrects airway inflammation in a humanized G551D rat	9
One percent of the clinical dose used for antenatal steroid therapy is sufficient to induce lung maturation when administered directly to the preterm ovine fetus	9
Dynamic positive end-expiratory pressure strategies using time and pressure recruitment at birth reduce early expression of lung injury in preterm lambs	9
A proteomics approach to identify COPD-related changes in lung fibroblasts	9
Optimization of long-term cold storage of rat precision-cut lung slices with a tissue preservation solution	9
Exposure to the heated tobacco product IQOS generates apoptosis-mediated pulmonary emphysema in murine lungs	9
GPx3 deficiency exacerbates maladaptive right ventricular remodeling in experimental pulmonary artery banding	9
Rapid postmortem ventilation improves donor lung viability by extending the tolerable warm ischemic time after cardiac death in mice	9
TRPC6, a therapeutic target for pulmonary hypertension	9
Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia	9
Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection	9
Optimizing miRNA transfection for screening in precision cut lung slices	9
Association of cystic fibrosis transmembrane conductance regulator with epithelial sodium channel subunits carrying Liddle’s syndrome mutations	9