American Journal of Physiology-Lung Cellular and Molecular Physiology

Papers
(The TQCC of American Journal of Physiology-Lung Cellular and Molecular Physiology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Two-pore potassium channel TREK-1 (K2P2.1) regulates NLRP3 inflammasome activity in macrophages173
ARDS in the time of corona: context and perspective89
Early-life exposure to cigarette smoke primes lung function and DNA methylation changes at Cyp1a1 upon exposure later in life73
Genes, other than Muc5b, play a role in bleomycin-induced lung fibrosis62
Feeling good: welcoming the new editorial team for American Journal of Physiology-Lung Cellular and Molecular Physiology62
The RNA-binding protein Quaking regulates multiciliated and basal cell abundance in the developing lung45
A toolbox for studying respiratory viral infections using air-liquid interface cultures of human airway epithelial cells42
IL-23 amplifies the epithelial-mesenchymal transition of mechanically conditioned alveolar epithelial cells in rheumatoid arthritis-associated interstitial lung disease through mTOR/S6 signaling41
Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea39
Ginger metabolites and metabolite-inspired synthetic products modulate intracellular calcium and relax airway smooth muscle38
The relationship between elastin cross linking and alveolar wall rupture in human pulmonary emphysema34
Peer Review Week, 202133
Looking at the developing lung in single-cell resolution33
Impact of neonatal noninvasive resuscitation strategies on lung mechanics, tracheal pressure, and tidal volume in preterm lambs32
PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition byPseudomonas aeruginosa32
Early extubation to noninvasive respiratory support of former preterm lambs improves long-term respiratory outcomes31
Control and challenge of COVID-19: lessons from China’s experience30
Short palate, lung, and nasal epithelial clone 1 (SPLUNC1) level determines steroid-resistant airway inflammation in aging29
Promoting our early career members at AJP-Lung: the Editorial Board Fellowship Program and the Next Generation Physiologist Highlights section at our Journal27
Simple model of pulmonary hypertension secondary to left heart pressure overload induced by partial intravascular occlusion of the ascending aorta26
Rat bronchoalveolar lavage proteome changes following e-cigarette aerosol exposures26
miR34a: a novel small molecule regulator with a big role in bronchopulmonary dysplasia25
Metformin prevents airway hyperreactivity in rats with dietary obesity25
Understanding the role of placental pathophysiology in the development of bronchopulmonary dysplasia25
Identification of Siglec-1-negative alveolar macrophages with proinflammatory phenotypes in chronic obstructive pulmonary disease24
The pontine Kölliker-Fuse nucleus is important for reduced postinspiratory airflow elicited by stimulation of the ventral respiratory parafacial region23
Mucociliary clearance is impaired in small airways of cystic fibrosis pigs23
Lung disease manifestations in Down syndrome22
The highly packed and dehydrated structure of preformed unexposed human pulmonary surfactant isolated from amniotic fluid22
Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs22
Hyperoxia impairs intraflagellar transport and causes dysregulated metabolism with resultant decreased cilia length22
Lung proteomic biomarkers associated with chronic obstructive pulmonary disease21
Reticulocalbin 3 deficiency in alveolar epithelium attenuated LPS-induced ALI via NF-κB signaling21
UCHL1, a deubiquitinating enzyme, regulates lung endothelial cell permeability in vitro and in vivo20
Analysis of the alveolar shape in 3-D20
Loss of growth differentiation factor 15 exacerbates lung injury in neonatal mice20
β-Agonist exposure preferentially impacts lung macrophage cyclic AMP-related gene expression in asthma and asthma COPD overlap syndrome19
Bulk RNA sequencing of human pediatric lung cell populations reveals unique transcriptomic signature associated with postnatal pulmonary development19
A personal appreciation of Mary Ellen Avery for World Prematurity Day18
Combined repetitive inhalant endotoxin and collagen-induced arthritis drive inflammatory lung disease and arthritis severity in a testosterone-dependent manner18
Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes18
Sex as a biologic variable: evidence from isolated lung endothelial cells18
Increased exploration and hyperlocomotion in a cigarette smoke and LPS-induced murine model of COPD: linking pulmonary and systemic inflammation with the brain18
Cigarette smoke depletes alveolar macrophages and delays clearance of Legionella pneumophila17
The oxygen dissociation curve of blood in COVID-1917
OGR1-dependent regulation of the allergen-induced asthma phenotype17
Reply to Cinelli et al.17
Impact of tidal volume strategy at birth on initiating lung injury in preterm lambs17
A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage17
Effect of smoking cessation on chronic waterpipe smoke inhalation-induced airway hyperresponsiveness, inflammation, and oxidative stress16
Reply to Gille et al.16
Biphasic regulation of miR-17∼92 transcription during hypoxia: roles of HIF1 and p53 hyperphosphorylation at ser1516
Calponin 1 contributes to myofibroblast differentiation of human pleural mesothelial cells16
PINK1 mediates the protective effects of thyroid hormone T3 in hyperoxia-induced lung injury16
Reply to Vogel et al.16
Comprehensive review of lipocalin 2-mediated effects in lung inflammation16
Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation15
Comparison of different methods of initiating lung inflammation and the sex-specific effects on inflammatory parameters15
Mice with lymphatic dysfunction develop pathogenic lung tertiary lymphoid organs that model an autoimmune emphysema phenotype of COPD15
Pulmonary-delivered Anticalin Jagged-1 antagonists reduce experimental airway mucus hyperproduction and obstruction15
Cellular mechanism underlying the facilitation of contractile response induced by IL-25 in mouse tracheal smooth muscle15
The aryl hydrocarbon receptor reduces LC3II expression and controls endoplasmic reticulum stress15
PDGFRα-positive cell-derived TIMP-1 modulates adaptive immune responses to influenza A viral infection15
The emerging role of extracellular vesicles in bronchopulmonary dysplasia15
PTPα promotes fibroproliferative responses after acute lung injury15
Noncanonical JAK1/STAT3 interactions with TGF-β modulate myofibroblast transdifferentiation and fibrosis15
A neutrophil subset defined by intracellular olfactomedin 4 is associated with mortality in sepsis15
Leukocyte kinetics and bacterial clearance during Streptococcus pneumoniae pneumonia and contributions of ICAM-115
T cell and airway smooth muscle interaction: a key driver of asthmatic airway inflammation and remodeling14
BATF2 enhances proinflammatory cytokine responses in macrophages and improves early host defense against pulmonary Klebsiella pneumoniae infection14
FGF18 promotes human lung branching morphogenesis through regulating mesenchymal progenitor cells14
Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma14
Cellular clocks in hyperoxia effects on [Ca2+]i regulation in developing human airway smooth muscle14
Endothelial knockdown of the tumor suppressor, WWOX, increases inflammation in ventilator-induced lung injury14
Distinct types of plexiform lesions identified by synchrotron-based phase-contrast micro-CT13
The developing murine lung is susceptible to acetaminophen toxicity13
A preclinical systematic review and meta-analysis assessing the effect of biological sex in lipopolysaccharide-induced acute lung injury13
Respiratory benefit in preterm lambs is progressively lost when the concentration of fetal plasma betamethasone is titrated below two nanograms per milliliter13
Metabolic signatures of ARDS and ARDS heterogeneity13
Are circulating endothelial cells the next target for transcriptome-level pathway analysis in ARDS?13
Continuous but not pulsed low-dose fetal betamethasone exposures extend the durability of antenatal steroid therapy13
cUMP elicits interendothelial gap formation during Pseudomonas aeruginosa infection13
Targeted stereology: sampling heterogeneously distributed structures and lesions in the lung13
GAA deficiency disrupts distal airway cells in Pompe disease13
Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced bySaccharopolyspora rectivirgula13
Oxidized phosphatidylcholines induce multiple functional defects in airway epithelial cells13
Evidence for reprogramming of monocytes into reparative alveolar macrophages in vivo by targeting PDE4b13
MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation13
Lung-kidney interactions and their role in chronic kidney disease-associated pulmonary diseases13
Sex differences and altered mitophagy in experimental pulmonary hypertension12
Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation12
Neonatal hyperoxia induces activated pulmonary cellular states and sex-dependent transcriptomic changes in a model of experimental bronchopulmonary dysplasia12
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease12
Isolation of high-yield and -quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts12
Immunoglobulin deficiency as an indicator of disease severity in patients with COVID-1912
Diet-induced obesity in mice impairs host defense against Klebsiella pneumonia in vivo and glucose transport and bactericidal functions in neutrophils in vitro12
Androgen receptor activation alleviates airway hyperresponsiveness, inflammation, and remodeling in a murine model of asthma12
IL-8 concurrently promotes idiopathic pulmonary fibrosis mesenchymal progenitor cell senescence and PD-L1 expression enabling escape from immune cell surveillance12
Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection12
Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-112
A gel-coated air-liquid-interface culture system with tunable substrate stiffness matching healthy and diseased lung tissues11
Respiratory diseases are whole body diseases: opportunities for growth in respiratory physiology11
The misuse of respiratory resistive loading during aerobic exercises: revisiting mechanisms of “standalone” inspiratory muscle training11
P2X7 signaling influences the production of pro-resolving and pro-inflammatory lipid mediators in alveolar macrophages derived from individuals with asthma11
A new anesthesia protocol enabling longitudinal lung-function measurements in neonatal rabbits by micro-CT11
Evidence of sex differences in ozone-induced oxysterol and cytokine levels in differentiated human nasal epithelial cells11
Exercise ventilatory response after COVID-19: comparison between ambulatory and hospitalized patients11
Gamma secretase activating protein promotes end-organ dysfunction after bacterial pneumonia11
Every Breath You Take: Exploring Macrophages and Environmental Exposures in the Lung—A Tribute to Dr. Joseph Brain's Legacy11
Moving on from clinical animal-derived surfactants to peptide-based synthetic pulmonary surfactant11
Endothelial metabolism in pulmonary vascular homeostasis and acute respiratory distress syndrome11
Towards in vivo Bronchoscopic Functional CFTR Assessment using a Short Circuit Current Measurement Probe11
Carotid bodies mediate glial cell activation and neuroinflammation in the NTS following long-term intermittent hypoxia: role in cardiorespiratory dysfunction11
BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance11
i stands for internet (and other things), not for inspired O2 concentration11
Viral airway injury promotes cell engraftment in an in vitro model of cystic fibrosis cell therapy11
Effects of spontaneous curvature on interfacial adsorption and collapse of phospholipid monolayers11
Spatiotemporal distribution of cellular injury and leukocytes during the progression of ventilator-induced lung injury11
Changes in respiratory mechanics in response to crystalloid infusions in extremely premature infants11
Intratracheal administration of mesenchymal stem cell-derived extracellular vesicles reduces lung injuries in a chronic rat model of bronchopulmonary dysplasia11
Congenital heart disease-associated pulmonary dysplasia and its underlying mechanisms11
Differentiating children with sepsis with and without acute respiratory distress syndrome using proteomics10
Hyaluronan/CD44 axis regulates S100A4-mediated mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis10
Validation of in vitro models for smoke exposure of primary human bronchial epithelial cells10
Chronic alcohol use primes bronchial cells for altered inflammatory response and barrier dysfunction during SARS-CoV-2 infection10
Maternal diabetes promotes offspring lung dysfunction and inflammation in a sex-dependent manner10
Therapeutic characteristics of alveolar-like macrophages in mouse models of hyperoxia and LPS-induced lung inflammation10
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa10
Genetic deficiency of the transcription factor NFAT1 confers protection against fibrogenic responses independent of immune influx10
Erythrocytes identify complement activation in patients with COVID-1910
Call for Papers: “In It for the Long Haul: Understanding the Lasting Impact of COVID-19 on Lung Health and Disease”10
Low-dose vanadium pentoxide perturbed lung metabolism associated with inflammation and fibrosis signaling in male animal and in vitro models10
Sex-specific differences in plasma levels of FXII, HK, and FXIIa-C1-esterase inhibitor complexes in community-acquired pneumonia10
Decreased LPS-induced lung injury in pigs treated with a lung surfactant protein A-derived nonapeptide that inhibits peroxiredoxin 6 activity and subsequent NOX1,2 activation10
Biomarkers of alveolar epithelial injury and endothelial dysfunction are associated with scores of pulmonary edema in invasively ventilated patients10
Lung metabolomics after ischemic acute kidney injury reveals increased oxidative stress, altered energy production, and ATP depletion10
Aryl hydrocarbon receptor activation alters immune cell populations in the lung and bone marrow during coronavirus infection10
Nephronectin is required to maintain right lung lobar separation during embryonic development10
Alexander von Humboldt (1769–1859): early high-altitude explorer and renowned plant naturalist10
Constitutive transgenic α-Klotho overexpression enhances resilience to and recovery from murine acute lung injury10
Thoracoabdominal asynchrony in a virtual preterm infant: computational modeling and analysis10
Diacetyl inhalation impairs airway epithelial repair in mice infected with influenza A virus9
Functional α7 nicotinic receptors in human airway smooth muscle increase intracellular calcium concentration and contractility in asthmatics9
Effect of estrogen receptor α on cardiopulmonary adaptation to chronic developmental hypoxia in a rat model9
Low-volume ventilation of preinjured lungs degrades lung function via stress concentration and progressive alveolar collapse9
Progesterone amplifies allergic inflammation and airway pathology in association with higher lung ILC2 responses9
Ataxia telangiectasia mutated is required for efficient proximal airway epithelial cell regeneration following influenza A virus infection9
Maternal high-fat diet changes breathing pattern and causes excessive sympathetic discharge in juvenile offspring rat9
Diesel exhaust particles induce polarization state-dependent functional and transcriptional changes in human monocyte-derived macrophages9
World AIDS Day: 40 years of an evolving pulmonary landscape9
Dysregulation of ion transport in the lung epithelium infected with SARS-CoV-29
Reply to Pantaleón García et al.9
Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS9
Impaired antiviral immunity in frequent exacerbators of chronic obstructive pulmonary disease9
Role of STIM1 in stretch-induced signaling in human airway smooth muscle9
ARDS Metabolic Fingerprints: Characterization, Benchmarking and Potential Mechanistic Interpretation9
Natural antibodies targeting LPS in pleural effusions of various etiologies9
Toll-like receptors: shapers of the pulmonary microbiome?9
Cross talk between LAM cells and fibroblasts may influence alveolar epithelial cell behavior in lymphangioleiomyomatosis9
Blockade of PD-1 decreases neutrophilic inflammation and lung damage in experimental COPD8
LL-37 and HMGB1 induce alveolar damage and reduce lung tissue regeneration via RAGE8
Exposure to carbon black nanoparticles during pregnancy aggravates lipopolysaccharide-induced lung injury in offspring: an intergenerational effect8
Cigarette smoke-induced airspace disease in mice develops independently of HIF-1α signaling in leukocytes8
A wrinkle in time: circadian biology in pulmonary vascular health and disease8
Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss8
RSV infection potentiates TRPV1-mediated calcium transport in bronchial epithelium of asthmatic children8
Reply to Myslivecek8
The mysterious case of missing lymphocytes: a cautionary tale of inter-institutional variability in outcomes of lung dissociation protocols8
Healing after COVID-19: are survivors at risk for pulmonary fibrosis?8
Age-associated differences in the human lung extracellular matrix8
Sensitive physiological readouts to evaluate countermeasures for lipopolysaccharide-induced lung alterations in mice8
Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis8
TLR4 is required for macrophage efferocytosis during resolution of ventilator-induced lung injury8
Inhibition of glutaminase 1 activity reverses airway hyperresponsiveness and decreases IL-1β+ M1s and IL-17 producing ILC3s in high-fat diet-fed obese mice8
Lung Endothelial Cell Heterogeneity in Health and Pulmonary Vascular Disease8
Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions8
Kidney-lung cross talk during ARDS: mitochondrial DAMPs join the conversation8
Muscarinic receptors in the nucleus tractus solitarii8
Dynamic driving pressure predicts ventilator-induced lung injury in mice with and without endotoxin-induced acute lung injury8
Balancing precision versus cohort transcriptomic analysis of acute and recovery phase of viral bronchiolitis8
Receptor-mediated activation of CFTR via prostaglandin signaling pathways in the airway8
Indocyanine-enhanced mouse model of bleomycin-induced lung fibrosis with hallmarks of progressive emphysema8
Lysyl oxidase regulation and protein aldehydes in the injured newborn lung8
Baseline reticular basement membrane morphology is related to subsequent spirometry deterioration in pediatric chronic airway inflammation: a follow-up study8
An update in club cell biology and its potential relevance to chronic obstructive pulmonary disease8
Therapeutic effects of high molecular weight hyaluronic acid in severe Pseudomonas aeruginosa pneumonia in ex vivo perfused human lungs8
CFTR as a therapeutic target for severe lung infection8
Brg1/PRMT5 nuclear complex epigenetically regulates FOXO1 in IPF mesenchymal progenitor cells8
Effects of hypoxia on respiratory diseases: perspective view of epithelial ion transport8
Citrullination, a novel posttranslational modification of elastin, is involved in COPD pathogenesis8
Stabilizing mast cells improves acute lung injury after orthotopic liver transplantation via promotion of apoptosis in polymorphonuclear neutrophils8
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