OOIR: Observatory of International Research

Papers

(The TQCC of International Journal of Oncology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Nuclear miRNAs as transcriptional regulators in processes related to various cancers (Review)	181
Identification and characterization of slow‑cycling cells in Ewing sarcoma	106
Aberrant alternative splicing in cancer: Splicing events and their regulatory mechanisms (Review)	81
Effect of DPP4/CD26 expression on SARS‑CoV‑2 susceptibility, immune response, adenosine (derivatives m⁶₂A and CD) regulations on patients with cancer and healthy individuals	72
miR‑383 increases the cisplatin sensitivity of lung adenocarcinoma cells through inhibition of the RBM24‑mediated NF‑κB signaling pathway	63
Histone lysine demethylase 3B regulates autophagy via transcriptional regulation of GABARAPL1 in acute myeloid leukemia cells	54
Modulation of PD‑L1 expression by standard therapy in head and neck cancer cell lines and exosomes	53
Role of miR‑181a‑5p in cancer (Review)	50
Human‑made electromagnetic fields: Ion forced‑oscillation and voltage‑gated ion channel dysfunction, oxidative stress and DNA damage (Review)	48
DNA methylation and breast cancer: A way forward (Review)	48
Tumor suppressive functions of hsa‑miR‑34a on cell cycle, migration and protective autophagy in bladder cancer	44
Anti‑angiogenic effect of Bryopsis plumosa‑derived peptide via aquaporin 3 in non‑small cell lung cancer	43
Butyrate supplementation regulates expression of chromosome segregation 1‑like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer	40
Roles of voltage‑gated potassium channels in the maintenance of pancreatic cancer stem cells	39
[Retracted] Feroniellin A‑induced autophagy causes apoptosis in multidrug‑resistant human A549 lung cancer cells	37
[Retracted] Interaction of YAP1 and mTOR promotes bladder cancer progression	36
Endocrine nuclear receptors and long non‑coding RNAs reciprocal regulation in cancer (Review)	34
GSTO1 confers drug resistance in HCT‑116 colon cancer cells through an interaction with TNFαIP3/A20	34
Targeting the cuproptosis‑associated gene COL22A1 in glioblastoma using EMD‑1204831 and kaempferol	33
MicroRNA‑153‑3p suppresses retinoblastoma cell growth and invasion via targeting the IGF1R/Raf/MEK and IGF1R/PI3K/AKT signaling pathways	32
CXCR4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K‑Akt‑mTOR pathway inhibition	31
Transgelin promotes ferroptosis to inhibit the malignant progression of esophageal squamous cell carcinoma	30
Genome‑wide DNA hypomethylation drives a more invasive pancreatic cancer phenotype and has predictive occult distant metastasis and prognosis potential	29
Targeting PIM2 by JP11646 results in significant antitumor effects in solid tumors	29
[Retracted] Interaction of S100A1 with LATS1 promotes cell growth through regulation of the Hippo pathway in hepatocellular carcinoma	29

Cinobufagin inhibits M2‑like tumor‑associated macrophage polarization to attenuate the invasion and migration of lung cancer cells	29
Epigenetic and epitranscriptomic role of lncRNA in carcinogenesis (Review)	28
Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin	28
Human cytomegalovirus infection enhances 5‑lipoxygenase and cycloxygenase‑2 expression in colorectal cancer	28
Molecular mechanisms and targeted therapy for the metastasis of prostate cancer to the bones (Review)	28
[Corrigendum] HIF-1α contributes to tube malformation of human lymphatic endothelial cells by upregulating VEGFR-3	27
Regulation of gliomagenesis and stemness through acid sensor ASIC1a	25
VIM‑AS1 promotes proliferation and drives enzalutamide resistance in prostate cancer via IGF2BP2‑mediated HMGCS1 mRNA stabilization	25
Aberrant acetylated modification of FGF21‑KLB signaling contributes to hepatocellular carcinoma metastasis through the β‑catenin pathway	25
Current research status of TNFAIP8 in tumours and other inflammatory conditions (Review)	25
Polydatin, a potential NOX5 agonist, synergistically enhances antitumor activity of cisplatin by stimulating oxidative stress in non‑small cell lung cancer	24
[Corrigendum] Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression	23
[Corrigendum] Receptor for activated C kinase 1 (RACK1) promotes the progression of OSCC via the AKT/mTOR pathway	23
Ageing microenvironment mediates lymphocyte carcinogenesis and lymphoma drug resistance: From mechanisms to clinical therapy (Review)	22
Abnormal expression of CDC25C in NSCLC is influenced by transcriptional and RNA N6‑methyladenosine‑mediated post‑transcriptional regulation	22
[Corrigendum] (‑)‑Epigallocatechingallate induces apoptosis in B lymphoma cells via caspase‑dependent pathway and Bcl‑2 family protein modulation	22
AUP1 transcriptionally activated by KDM5B reprograms lipid metabolism to promote the malignant progression of cervical cancer	21
Advancements in colorectal cancer research: Unveiling the cellular and molecular mechanisms of neddylation (Review)	21
[Retracted] MicroRNA‑132 inhibits cell growth and metastasis in osteosarcoma cell lines possibly by targeting Sox4	20
Arsenic compounds induce apoptosis by activating the MAPK and caspase pathways in FaDu oral squamous carcinoma cells	20
[Corrigendum] DJ‑1 promotes cell proliferation and tumor metastasis in esophageal squamous cell carcinoma via the Wnt/β‑catenin signaling pathway	20
A multi‑omics study of diagnostic markers and the unique inflammatory tumor micro‑environment involved in tuberous sclerosis complex‑related renal angiomyolipoma	20
[Retracted] Effects of RUNX3 mediated Notch signaling pathway on biological characteristics of colorectal cancer cells	19
Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β‑catenin/N‑cadherin axis	19
Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS‑activated pancreatic cancer cells	19
[Corrigendum] Long non‑coding RNA CASC11 interacts with YBX1 to promote prostate cancer progression by suppressing the p53 pathway	19
[Retracted] miR‑802 inhibits the aggressive behaviors of non‑small cell lung cancer cells by directly targeting FGFR1	19
Role of miRNA‑122 in cancer (Review)	18
Anti‑PD‑1/PD‑L1 and anti‑CTLA‑4 associated checkpoint inhibitor pneumonitis in non‑small cell lung cancer: Occurrence, pathogenesis and risk factors (Review)	18
GDNF regulates lipid metabolism and glioma growth through RET/ERK/HIF‑1/SREBP‑1	18
PHF20 inhibition promotes apoptosis and cisplatin chemosensitivity via the OCT4‑p‑STAT3‑MCL1 signaling pathway in hypopharyngeal squamous cell carcinoma	18
An overview of the regulatory role of annexin A1 in the tumor microenvironment and its prospective clinical application (Review)	18
Revolutionizing breast cancer treatment: Harnessing the related mechanisms and drugs for regulated cell death (Review)	18
[Retracted] MicroRNA‑873 targets HOXA9 to inhibit the aggressive phenotype of osteosarcoma by deactivating the Wnt/β‑catenin pathway	17
The regulatory effect of the YY1/miR‑HCC2/BAMBI axis on the stemness of liver cancer cells	17
lncRNA deregulation in childhood acute lymphoblastic leukemia: A systematic review	17
Prolyl hydroxylase 2 inhibits glycolytic activity in colorectal cancer via the NF‑κB signaling pathway	17
Role of DCLK1 in oncogenic signaling (Review)	16
Emerging proteins involved in castration‑resistant prostate cancer via the AR‑dependent and AR‑independent pathways (Review)	16
Effect of duty cycles of tumor‑treating fields on glioblastoma cells and normal brain organoids	16
Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells	16
[Corrigendum] miR-382 inhibits migration and invasion by targeting ROR1 through regulating EMT in ovarian cancer	16
LGR4 promotes proliferation and homing via activation of the NF‑κB signaling pathway in multiple myeloma	16
HepaCAM‑PIK3CA axis regulates the reprogramming of glutamine metabolism to inhibit prostate cancer cell proliferation	16
Aurantio‑obtusin regulates lipogenesis and ferroptosis of liver cancer cells through inhibiting SCD1 and sensitizing RSL3	16
[Retracted] NR4A1‑induced increase in the sensitivity of a human gastric cancer line to TNFα‑mediated apoptosis is associated with the inhibition of JNK/Parkin‑dependent mitophagy	16
Mechanism of exosomes in the tumor microenvironment in the abscopal effect (Review)	15
Significance of signal recognition particle 9 nuclear translocation: Implications for pancreatic cancer prognosis and functionality	15
Research progress on PRMTs involved in epigenetic modification and tumour signalling pathway regulation (Review)	15
RPL9 acts as an oncogene by shuttling miRNAs through exosomes in human hepatocellular carcinoma cells	15

Emerging role of bile acids in colorectal liver metastasis: From molecular mechanism to clinical significance (Review)	15
Tumor immune microenvironment and the current immunotherapy of cholangiocarcinoma (Review)	15
[Retracted] MicroRNA‑664 targets paired box protein 6 to inhibit the oncogenicity of pancreatic ductal adenocarcinoma	15
Antitumor effect of memantine is related to the formation of the splicing isoform of GLG1, a decoy FGF‑binding protein	15
GBP2 enhances paclitaxel sensitivity in triple‑negative breast cancer by promoting autophagy in combination with ATG2 and inhibiting the PI3K/AKT/mTOR pathway	15
[Retracted] Promoter methylation of RASSF1A modulates the effect of the microtubule‑targeting agent docetaxel in breast cancer	15
Exosome as a crucial communicator between tumor microenvironment and gastric cancer (Review)	14
Cancer‑associated fibroblast‑induced M2‑polarized macrophages promote hepatocellular carcinoma progression via the plasminogen activator inhibitor‑1 pathway	14
Cucurbitacin IIa promotes the immunogenic cell death‑inducing effect of doxorubicin and modulates immune microenvironment in liver cancer	14
Targeting the mTOR pathway using novel ATP‑competitive inhibitors, Torin1, Torin2 and XL388, in the treatment of glioblastoma	14
[Retracted] Tripartite motif 16 inhibits hepatocellular carcinoma cell migration and invasion	14
miR‑382 inhibits breast cancer progression and metastasis by affecting the M2 polarization of tumor‑associated macrophages by targeting PGC‑1α	14
Complement regulatory protein CD46 promotes bladder cancer metastasis through activation of MMP9	13
[Corrigendum] The role of IGFBP‑5 in mediating the anti‑proliferation effect of tetrandrine in human colon cancer cells	13
Ex vivo assessment of cancer drug sensitivity in epithelial ovarian cancer and its association with histopathological type, treatment history and clinical outcome	13
[Corrigendum] Adenoviral neutral endopeptidase gene delivery in combination with paclitaxel for the treatment of prostate cancer	13
MicroRNA in adenoid cystic carcinoma (Review)	13
Correlation of SARS‑CoV‑2 to cancer: Carcinogenic or anticancer? (Review)	13
Roles of exosomes in cancer chemotherapy resistance, progression, metastasis and immunity, and their clinical applications (Review)	13
EDITORIAL The International Journal of Oncology: 30 years of progress (1992-2021)	13
Effects of exosomes on tumor immunomodulation and their potential clinical applications (Review)	13
LncCCAT1 interaction protein PKM2 upregulates SREBP2 phosphorylation to promote osteosarcoma tumorigenesis by enhancing the Warburg effect and lipogenesis	12
Epigenetic silencing of ZCCHC10 by the lncRNA SNHG1 promotes progression and venetoclax resistance of acute myeloid leukemia	12
Biological functions of circRNA in regulating the hallmarks of gastrointestinal cancer (Review)	12
[Corrigendum] Linc00961 inhibits the proliferation and invasion of skin melanoma by targeting the miR‑367/PTEN axis	12
Roles of salt‑inducible kinases in cancer (Review)	12
MELK predicts poor prognosis and promotes metastasis in esophageal squamous cell carcinoma via activating the NF‑κB pathway	12
lncRNA SNHG22 sponges miR‑128‑3p to promote the progression of colorectal cancer by upregulating E2F3	12
[Retracted] MiR‑132 inhibits cell proliferation, invasion and migration of hepatocellular carcinoma by targeting PIK3R3	12
[Corrigendum] Wnt‑signaling and apoptosis after neoadjuvant short‑term radiotherapy for rectal cancer	12
[Corrigendum] METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma	12
Establishment of patient‑derived lung tumorspheres and their response to internal irradiation by Auger electrons	12
FGFR‑related phenotypic and functional profile of CAFs in prognostication of breast cancer (Review)	12
Chimeric HDAC and the cytoskeleton inhibitor broxbam as a novel therapeutic strategy for liver cancer	12
[Retracted] Expression and function of PIM kinases in osteosarcoma	12
Targeting mitochondrial bioenergetics by combination treatment with imatinib and dichloroacetate in human erythroleukemic K‑562 and colorectal HCT‑116 cancer cells	12
Epigenetic modifications in acute myeloid leukemia: The emerging role of circular RNAs (Review)	11
Tumour follower cells: A novel driver of leader cells in collective invasion (Review)	11
Circular RNAs in osteosarcoma: An update of recent studies (Review)	11
Receptor for activated C kinase 1 promotes cervical cancer lymph node metastasis via the glycolysis‑dependent AKT/mTOR signaling	11
Use of conditional reprogramming cell, patient derived xenograft and organoid for drug screening for individualized prostate cancer therapy: Current and future perspectives (Review)	11
[Retracted] Slug contributes to cancer progression by direct regulation of ERα signaling pathway	11
New developments in the mechanism and application of immune checkpoint inhibitors in cancer therapy (Review)	10
Visfatin inhibits colon cancer cell apoptosis and decreases chemosensitivity to 5‑FU by promoting the SDF‑1/CXCR4/Akt axis	10
Collagen type VI‑α1 and 2 repress the proliferation, migration and invasion of bladder cancer cells	10
RPL27 contributes to colorectal cancer proliferation and stemness via PLK1 signaling	10
Epigallocatechin‑3‑gallate hinders metabolic coupling to suppress colorectal cancer malignancy through targeting aerobic glycolysis in cancer‑associated fibroblasts	10
Lactoferrin may inhibit the development of cancer via its immunostimulatory and immunomodulatory activities	10
USP35 promotes hepatocellular carcinoma progression by protecting PKM2 from ubiquitination‑mediated degradation	10
Lnc‑RGS5 sponges miR‑542‑5p to promote FoxM1/VEGFA signaling and breast cancer cell proliferation	10
Targeting drug resistance in glioblastoma (Review)	10
m⁶A‑modified HOXC10 promotes HNSCC progression via co‑activation of ADAM17/EGFR and Wnt/β‑catenin signaling	10
lncRNA cytoskeleton regulator reduces non‑small cell lung cancer radiosensitivity by downregulating miRNA‑206 and activating prothymosin α	10
Ribosome 18S m⁶A methyltransferase METTL5 promotes pancreatic cancer progression by modulating c‑Myc translation	10
Identification of recurrent 3q13.31 chromosomal rearrangement indicates LSAMP as a tumor suppressor gene in neuroblastoma	10
Chimeric antigen receptor T cells in the treatment of osteosarcoma (Review)	10
Function of microRNA‑124 in the pathogenesis of cancer (Review)	10
[Retracted] lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β‑catenin pathway in oral squamous cell carcinoma	10
lncRNA NEAT1 facilitates the progression of colorectal cancer via the KDM5A/Cul4A and Wnt signaling pathway	10
Controversial roles of cold‑inducible RNA‑binding protein in human cancer (Review)	10
Antimicrobial agent chloroxylenol targets β‑catenin‑mediated Wnt signaling and exerts anticancer activity in colorectal cancer	10
[Corrigendum] Curcumin reverses benzidine-induced epithelial-mesenchymal transition via suppression of ERK5/AP-1 in SV-40 immortalized human urothelial cells	10
Inhibition of the NOTCH and mTOR pathways by nelfinavir as a novel treatment for T cell acute lymphoblastic leukemia	10