OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Oncology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Mechanisms and management of 3rd‑generation EGFR‑TKI resistance in advanced non‑small cell lung cancer (Review)	129
Cancer‑associated fibroblast‑induced M2‑polarized macrophages promote hepatocellular carcinoma progression via the plasminogen activator inhibitor‑1 pathway	85
Serine, glycine and one‑carbon metabolism in cancer (Review)	78
A multidisciplinary approach remains the best strategy to improve and strengthen the management of ovarian cancer (Review)	73
Current molecular and clinical insights into uveal melanoma (Review)	54
Immune-checkpoint inhibitors from cancer to COVID‑19: A promising avenue for the treatment of patients with COVID‑19 (Review)	51
‘Reverse Warburg effect’ of cancer‑associated fibroblasts (Review)	42
N6‑methyladenosine upregulates miR‑181d‑5p in exosomes derived from cancer‑associated fibroblasts to inhibit 5‑FU sensitivity by targeting NCALD in colorectal cancer	42
Human‑made electromagnetic fields: Ion forced‑oscillation and voltage‑gated ion channel dysfunction, oxidative stress and DNA damage (Review)	40
Signaling pathways and therapeutic approaches in glioblastoma multiforme (Review)	40
Role of macrophages in tumor progression and therapy (Review)	39
Riluzole: A neuroprotective drug with potential as a novel anti‑cancer agent (Review)	38
NUPR1 and its potential role in cancer and pathological conditions (Review)	34
Curcumin inhibits the cancer‑associated fibroblast‑derived chemoresistance of gastric cancer through the suppression of the JAK/STAT3 signaling pathway	33
Critical role of mTOR in regulating aerobic glycolysis in carcinogenesis (Review)	31
Long non‑coding RNA nuclear paraspeckle assembly transcript 1 regulates ionizing radiation‑induced pyroptosis via microRNA‑448/gasdermin E in colorectal cancer cells	29
Sequestosome 1/p62: A multitasker in the regulation of malignant tumor aggression (Review)	28
MUC1 is an oncoprotein with a significant role in apoptosis (Review)	28
Role of Nectin‑4 protein in cancer (Review)	28
DNA methylation and breast cancer: A way forward (Review)	26
Exosomal transfer of miR‑25‑3p promotes the proliferation and temozolomide resistance of glioblastoma cells by targeting FBXW7	26
Regulatory effect of the MAFG‑AS1/miR‑150‑5p/MYB axis on the proliferation and migration of breast cancer cells	25
Association of the microbiome with colorectal cancer development (Review)	24
Ribosome 18S m⁶A methyltransferase METTL5 promotes pancreatic cancer progression by modulating c‑Myc translation	24
Underlying metastasis mechanism and clinical application of exosomal circular RNA in tumors (Review)	24

CYP11A1‑derived vitamin D hydroxyderivatives as candidates for therapy of basal and squamous cell carcinomas	24
Collagen type VI‑α1 and 2 repress the proliferation, migration and invasion of bladder cancer cells	23
Crosstalk between YAP and TGFβ regulates SERPINE1 expression in mesenchymal lung cancer cells	23
Novel PI3K/Akt/mTOR signaling inhibitor, W922, prevents colorectal cancer growth via the regulation of autophagy	23
Emerging roles and mechanisms of microRNA‑222‑3p in human cancer (Review)	23
Identification of the most common BRCA alterations through analysis of germline mutation databases: Is droplet digital PCR an additional strategy for the assessment of such alterations in breast and o	22
Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2	22
Chitinase 3-like 1 secreted from cancer-associated fibroblasts promotes tumor angiogenesis via interleukin-8 secretion in colorectal cancer	22
Overall survival in stage IV EGFR mutation‑positive NSCLC: Comparing first‑, second‑ and third‑generation EGFR‑TKIs (Review)	20
Three‑dimensional models to study breast cancer (Review)	19
Effects of PI3K and FGFR inhibitors alone and in combination, and with/without cytostatics in childhood neuroblastoma cell lines	19
WBSCR22 and TRMT112 synergistically suppress cell proliferation, invasion and tumorigenesis in pancreatic cancer via transcriptional regulation of ISG15	19
Clinical crosstalk between microRNAs and gastric cancer (Review)	19
Roles of exosomes in cancer chemotherapy resistance, progression, metastasis and immunity, and their clinical applications (Review)	19
lncRNA cytoskeleton regulator reduces non‑small cell lung cancer radiosensitivity by downregulating miRNA‑206 and activating prothymosin α	19
Cellular metabolism in pancreatic cancer as a tool for prognosis and treatment (Review)	19
Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways	19
Role of telomere length in human carcinogenesis (Review)	19
Novel insights on gut microbiota manipulation and immune checkpoint inhibition in cancer (Review)	19
circUBAP2 regulates osteosarcoma progression via the miR‑204‑3p/HMGA2 axis	19
Stromal cells in the tumor microenvironment promote the progression of oral squamous cell carcinoma	18
Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules	18
PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1	18
Correlation of SARS‑CoV‑2 to cancer: Carcinogenic or anticancer? (Review)	18
Research status and prospects of biomarkers for nasopharyngeal carcinoma in the era of high‑throughput omics (Review)	18
Dual inhibition of EGFR‑VEGF: An effective approach to the treatment of advanced non‑small cell lung cancer with EGFR mutation (Review)	18
TGF‑β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway	18
Blocking the Wnt/β‑catenin signaling pathway to treat colorectal cancer: Strategies to improve current therapies (Review)	18
NcRNAs: Multi‑angle participation in the regulation of glioma chemotherapy resistance (Review)	18
Interleukin‑8 released by cancer‑associated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells	18
High‑throughput screening identification of a small‑molecule compound that induces ferroptosis and attenuates the invasion and migration of hepatocellular carcinoma cells by targeting the STAT3/GPX4 a	18
TRIM35 ubiquitination regulates the expression of PKM2 tetramer and dimer and affects the malignant behaviour of breast cancer by regulating the Warburg effect	18
Role of stress in the pathogenesis of cancer (Review)	17
Immunotherapy for nasopharyngeal carcinoma: Current status and prospects (Review)	17
Exosomes released by imatinib‑resistant K562 cells contain specific membrane markers, IFITM3, CD146 and CD36 and increase the survival of imatinib‑sensitive cells in the presence of imatinib	17
Lactoferrin may inhibit the development of cancer via its immunostimulatory and immunomodulatory activities	17
Everolimus therapy and side‑effects: A systematic review and meta‑analysis	17
Combined inhibition of IL‑6 and IL‑8 pathways suppresses ovarian cancer cell viability and migration and tumor growth	17
Epigallocatechin‑3‑gallate hinders metabolic coupling to suppress colorectal cancer malignancy through targeting aerobic glycolysis in cancer‑associated fibroblasts	16
Elevation of ADAM12 facilitates tumor progression by enhancing metastasis and immune infiltration in gastric cancer	16
Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL‑6/STAT3 signaling pathway	15
Mechanism of multidrug resistance to chemotherapy mediated by P‑glycoprotein (Review)	15
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma	15
SEPT6 drives hepatocellular carcinoma cell proliferation, migration and invasion via the Hippo/YAP signaling pathway	15
Exosomal ANXA1 derived from thyroid cancer cells is associated with malignant transformation of human thyroid follicular epithelial cells by promoting cell proliferation	15
The TLR7/8 agonist R848 optimizes host and tumor immunity to improve therapeutic efficacy in murine lung cancer	15
circ‑LRP6 contributes to osteosarcoma progression by regulating the miR‑141‑3p/HDAC4/HMGB1 axis	15
Diagnosis, prognosis and treatment of primary central nervous system lymphoma in the elderly population (Review)	15
Immunological modulation of the Th1/Th2 shift by ionizing radiation in tumors (Review)	15
Isolation and analysis of tumor‑derived extracellular vesicles from head and neck squamous cell carcinoma plasma by galectin‑based glycan recognition particles	14

lncRNA SNHG22 sponges miR‑128‑3p to promote the progression of colorectal cancer by upregulating E2F3	14
Parthenolide inhibits the tumor characteristics of renal cell carcinoma	14
Hypoplastic myelodysplastic syndrome and acquired aplastic anemia: Immune‑mediated bone marrow failure syndromes (Review)	14
Increased expression of PSME2 is associated with clear cell renal cell carcinoma invasion by regulating BNIP3‑mediated autophagy	14
CXCR4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K‑Akt‑mTOR pathway inhibition	14
lncRNA ST3GAL6‑AS1 promotes invasion by inhibiting hnRNPA2B1‑mediated ST3GAL6 expression in multiple myeloma	13
Exosomal proteins: Key players mediating pre‑metastatic niche formation and clinical implications (Review)	13
Potential of the tumor‑derived extracellular vesicles carrying the miR‑125b‑5p target TNFAIP3 in reducing the sensitivity of diffuse large B cell lymphoma to rituximab	13
Epigenetic modification regulates tumor progression and metastasis through EMT (Review)	13
Galectin‑1 binds GRP78 to promote the proliferation and metastasis of gastric cancer	13
Doramectin inhibits glioblastoma cell survival via regulation of autophagy in vitro and in vivo	13
Targeting the mTOR pathway using novel ATP‑competitive inhibitors, Torin1, Torin2 and XL388, in the treatment of glioblastoma	13
Exploring histopathological and serum biomarkers in lung adenocarcinoma: Clinical applications and translational opportunities (Review)	13
New insights into the management of differentiated thyroid carcinoma in children and adolescents (Review)	13
Interaction of tumor‑associated macrophages with stromal and immune components in solid tumors: Research progress (Review)	12
Potential of antiviral drug oseltamivir for the treatment of liver cancer	12
lncRNA HCP5 acts as a ceRNA to regulate EZH2 by sponging miR‑138‑5p in cutaneous squamous cell carcinoma	12
Roles of small extracellular vesicles in the development, diagnosis and possible treatment strategies for hepatocellular carcinoma (Review)	12
Anterior gradient protein 2 is a marker of tumor aggressiveness in breast cancer and favors chemotherapy‑induced senescence escape	12
Ricolinostat enhances adavosertib‑induced mitotic catastrophe in TP53‑mutated head and neck squamous cell carcinoma cells	12
LINC00514 promotes lipogenesis and tumor progression in esophageal squamous cell carcinoma by sponging miR‑378a‑5p to enhance SPHK1 expression	12
Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells	12
Loss of cell division cycle‑associated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinoma	12
Role of the tumor microenvironment in cancer hallmarks and targeted therapy (Review)	12
Circadian clock as a possible control point in colorectal cancer progression (Review)	12
Regulation of gliomagenesis and stemness through acid sensor ASIC1a	11
Tumor suppressive functions of hsa‑miR‑34a on cell cycle, migration and protective autophagy in bladder cancer	11
Glioma‑neuronal interactions in tumor progression: Mechanism, therapeutic strategies and perspectives (Review)	11
miR‑382 inhibits breast cancer progression and metastasis by affecting the M2 polarization of tumor‑associated macrophages by targeting PGC‑1α	11
Research progress on immunotherapy in triple‑negative breast cancer (Review)	11
MicroRNA‑301a/ZNRF3/wnt/β‑catenin signal regulatory crosstalk mediates glioma progression	11
LncCCAT1 interaction protein PKM2 upregulates SREBP2 phosphorylation to promote osteosarcoma tumorigenesis by enhancing the Warburg effect and lipogenesis	11
Retrospective analysis of the preparation and application of immunotherapy in cancer treatment (Review)	11
Parenteral high‑dose ascorbate - A possible approach for the treatment of glioblastoma (Review)	11
Roles of Rho‑associated kinase in lung cancer (Review)	11
Recent progress of circular RNAs in different types of human cancer: Technological landscape, clinical opportunities and challenges (Review)	11
Treatment optimization of locally advanced and metastatic pancreatic cancer (Review)	11
PD‑1/PD‑L1 immune checkpoint inhibitors in neoadjuvant therapy for solid tumors (Review)	10
lncRNA GAS5, as a ceRNA, inhibits the proliferation of diffuse large B‑cell lymphoma cells by regulating the miR‑18a‑5p/RUNX1 axis	10
Functional assessment of miR‑1291 in colon cancer cells	10
lncRNA NEAT1 facilitates the progression of colorectal cancer via the KDM5A/Cul4A and Wnt signaling pathway	10
Epigenetic modifications in acute myeloid leukemia: The emerging role of circular RNAs (Review)	10
Butyrate supplementation regulates expression of chromosome segregation 1‑like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer	10
HHLA2 promotes tumor progression by long non‑coding RNA H19 in human gallbladder cancer	10
Guanosine monophosphate synthase upregulation mediates cervical cancer progression by inhibiting the apoptosis of cervical cancer cells via the Stat3/P53 pathway	10
Bispecific GPC3/PD‑1 CAR‑T cells for the treatment of HCC	10
Macrophage migration inhibitory factor in the pathogenesis of leukemia (Review)	10
TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex	10
Long non‑coding RNA 01614 hyperactivates WNT/β‑catenin signaling to promote pancreatic cancer progression by suppressing GSK‑3β	10
Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR/PI3K/AKT pathway	10
DYRK1A suppression attenuates HIF‑1α accumulation and enhances the anti‑liver cancer effects of regorafenib and sorafenib under hypoxic conditions	10
Efficacy of birinapant in combination with carboplatin in targeting platinum‑resistant epithelial ovarian cancers	10
TDO2 modulates liver cancer cell migration and invasion via the Wnt5a pathway	10
Use of conditional reprogramming cell, patient derived xenograft and organoid for drug screening for individualized prostate cancer therapy: Current and future perspectives (Review)	10
Effect of DPP4/CD26 expression on SARS‑CoV‑2 susceptibility, immune response, adenosine (derivatives m⁶₂A and CD) regulations on patients with cancer and healthy individuals	10
MicroRNA‑198 suppresses tumour growth and metastasis in oral squamous cell carcinoma by targeting CDK4	10
Early detection of tumor cells in bone marrow and peripheral blood in a fast‑progressing gastric cancer model	9
Knockdown of TMED3 inhibits cell viability and migration and increases apoptosis in human chordoma cells	9
miR‑383 increases the cisplatin sensitivity of lung adenocarcinoma cells through inhibition of the RBM24‑mediated NF‑κB signaling pathway	9
Spine‑specific downregulation of LAPTM5 expression promotes the progression and spinal metastasis of estrogen receptor‑positive breast cancer by activating glutamine‑dependent mTOR signaling	9
A potential tumor marker: Chaperonin containing TCP‑1 controls the development of malignant tumors (Review)	9
PD‑L1 mediates triple‑negative breast cancer evolution via the regulation of TAM/M2 polarization	9
Controversial roles of cold‑inducible RNA‑binding protein in human cancer (Review)	9
Visfatin inhibits colon cancer cell apoptosis and decreases chemosensitivity to 5‑FU by promoting the SDF‑1/CXCR4/Akt axis	9
Novel therapies for malignant pleural effusion: Anti‑angiogenic therapy and immunotherapy (Review)	9
Cisplatin enhances protein O‑GlcNAcylation by altering the activity of OGT, OGA and AMPK in human non‑small cell lung cancer cells	9
Endoplasmic reticulum stress‑induced cell death as a potential mechanism for targeted therapy in glioblastoma (Review)	9
APR-246 combined with 3-deazaneplanocin A, panobinostat or temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells	9
Hepatocellular carcinoma: Novel understandings and therapeutic strategies based on bile acids (Review)	9
Matrix metalloproteinase‑1 expression is regulated by HIF‑1‑dependent and epigenetic mechanisms and serves a tumor‑suppressive role in gastric cancer progression	9
Recent advances in postoperative pulmonary rehabilitation of patients with non‑small cell lung cancer (Review)	9
Research progress on PRMTs involved in epigenetic modification and tumour signalling pathway regulation (Review)	9
Biomarkers and 3D models predicting response to immune checkpoint blockade in head and neck cancer (Review)	9
MicroRNA‑93 knockdown inhibits acute myeloid leukemia cell growth via inactivating the PI3K/AKT pathway by upregulating DAB2	9
The role of non‑coding RNAs in the regulation, diagnosis, prognosis and treatment of osteosarcoma (Review)	8
Novel insight into the functions of N⁶‑methyladenosine modified lncRNAs in cancers (Review)	8
HNF1A regulates oxaliplatin resistance in pancreatic cancer by targeting 53BP1	8
Cancer testis antigen subfamilies: Attractive targets for therapeutic vaccine (Review)	8
Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating β‑catenin and increases irinotecan sensitivity in colorectal cancer	8
Roles of ubiquitination in the crosstalk between tumors and the tumor microenvironment (Review)	8

Eupalinolide A induces autophagy via the ROS/ERK signaling pathway in hepatocellular carcinoma cells in vitro and in vivo	8
Periodontal disease affects oral cancer progression in a surrogate animal model for tobacco exposure	8
Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti‑tubulin tetrahydrothieno[2,3‑c]pyridine derivative and a peptide nucleic acid targeting miR‑221‑3p	8
MicroRNA‑153‑3p suppresses retinoblastoma cell growth and invasion via targeting the IGF1R/Raf/MEK and IGF1R/PI3K/AKT signaling pathways	8
Claudin‑9 is a novel prognostic biomarker for endometrial cancer	8
Molecular mechanism, regulation, and therapeutic targeting of the STAT3 signaling pathway in esophageal cancer (Review)	8
Epithelial membrane protein 3 regulates lung cancer stem cells via the TGF‑β signaling pathway	8
Receptor for activated C kinase 1 promotes cervical cancer lymph node metastasis via the glycolysis‑dependent AKT/mTOR signaling	8
Treatment of patients with cancer using PD‑1/PD‑L1 antibodies: Adverse effects and management strategies (Review)	8
An emerging role of radiation‑induced exosomes in hepatocellular carcinoma progression and radioresistance (Review)	7
Epigenetic modifications: Critical participants of the PD‑L1 regulatory mechanism in solid tumors (Review)	7
m⁶A‑mediated LINC02038 inhibits colorectal cancer progression via regulation of the FAM172A/PI3K/AKT pathway via competitive binding with miR‑552‑5p	7
Protein disulfide isomerase A1‑associated pathways in the development of stratified breast cancer therapies	7
Aspirin inhibits cholangiocarcinoma cell proliferation via cell cycle arrest in vitro and in vivo	7
Realgar‑induced KRAS mutation lung cancer cell death via KRAS/Raf/MAPK mediates ferroptosis	7
Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS‑activated pancreatic cancer cells	7
KDM5B protein expressed in viable and fertile ΔARID mice exhibit no demethylase activity	7
Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β‑catenin/N‑cadherin axis	7
Combined PARP inhibitors and small molecular inhibitors in solid tumor treatment (Review)	7
Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma	7
Oncogenic role of abnormal spindle‑like microcephaly‑associated protein in lung adenocarcinoma	7
Advances in immune therapies for the treatment of microsatellite instability‑high/deficient mismatch repair metastatic colorectal cancer (Review)	7
Extracellular vesicle‑mediated miR‑126‑3p transfer contributes to inter‑cellular communication in the liver tumor microenvironment	7
Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes	7
Arsenic compounds induce apoptosis by activating the MAPK and caspase pathways in FaDu oral squamous carcinoma cells	7
Real‑world challenge for clinicians treating advanced gastroesophageal adenocarcinoma (Review)	7
Human L‑asparaginase: Acquiring knowledge of its activation (Review)	7
Antitumor effects of curcumin in pediatric rhabdomyosarcoma in combination with chemotherapy and phototherapy in vitro	7
circRPS19 affects HK2‑mediated aerobic glycolysis and cell viability via the miR‑125a‑5p/USP7 pathway in gastric cancer	7
Effects of glycolysis on the polarization and function of tumor‑associated macrophages (Review)	7
Epigenetic silencing of ZCCHC10 by the lncRNA SNHG1 promotes progression and venetoclax resistance of acute myeloid leukemia	7
Targeting histone demethylases as a potential cancer therapy (Review)	7
Roles of voltage‑gated potassium channels in the maintenance of pancreatic cancer stem cells	7
Self‑renewal signaling pathways and differentiation therapies of glioblastoma stem cells (Review)	7
QPCT regulation by CTCF leads to sunitinib resistance in renal cell carcinoma by promoting angiogenesis	7
TRAP1 regulates the response of colorectal cancer cells to hypoxia and inhibits ribosome biogenesis under conditions of oxygen deprivation	7
The inhibitory effect of CTAB on human osteosarcoma through the PI3K/AKT signaling pathway	7
O‑GlcNAcylation mediates endometrial cancer progression by regulating the Hippo‑YAP pathway	6
Human leukocyte antigen and tumor immunotherapy (Review)	6
Holliday junction recognition protein as a prognostic biomarker and therapeutic target for oral cancer	6
NADPH oxidase 5 has a crucial role in cellular motility of colon cancer cells	6
Obesity, colorectal cancer and MACC1 expression: A possible novel molecular association	6
GSTO1 confers drug resistance in HCT‑116 colon cancer cells through an interaction with TNFαIP3/A20	6
Effects of exosomes on tumor immunomodulation and their potential clinical applications (Review)	6
FIGNL1 promotes non‑small cell lung cancer cell proliferation	6
Role of DCLK1 in oncogenic signaling (Review)	6
Effect of duty cycles of tumor‑treating fields on glioblastoma cells and normal brain organoids	6
Activation of DDX58/RIG‑I suppresses the growth of tumor cells by inhibiting STAT3/CSE signaling in colon cancer	6
Current research status of TNFAIP8 in tumours and other inflammatory conditions (Review)	6
Differential dependency of human glioblastoma cells on vascular endothelial growth factor‑A signaling via neuropilin‑1	6
RPL27 contributes to colorectal cancer proliferation and stemness via PLK1 signaling	6
Isatin inhibits the invasion and metastasis of SH‑SY5Y neuroblastoma cells in vitro and in vivo	6
Crosstalk between cancer and different cancer stroma subtypes promotes the infiltration of tumor‑associated macrophages into the tumor microenvironment of oral squamous cell carcinoma	6
Altered expression of the IGF2‑H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma	6
A chondroitin sulfate proteoglycan 4‑specific monoclonal antibody inhibits melanoma cell invasion in a spheroid model	6
PHF20 inhibition promotes apoptosis and cisplatin chemosensitivity via the OCT4‑p‑STAT3‑MCL1 signaling pathway in hypopharyngeal squamous cell carcinoma	6
Death associated protein‑3 (DAP3) and DAP3 binding cell death enhancer‑1 (DELE1) in human colorectal cancer, and their impacts on clinical outcome and chemoresistance	6
Aptamer‑based therapy for targeting key mediators of cancer metastasis (Review)	6
Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma	6
lncKRT16P6 promotes tongue squamous cell carcinoma progression by sponging miR‑3180 and regulating GATAD2A expression	5
Circular RNAs in osteosarcoma: An update of recent studies (Review)	5
HER2⁺ advanced gastric cancer: Current state and opportunities (Review)	5
Novel insights into the impact of the SUMOylation pathway in hematological malignancies (Review)	5
Advances in understanding the role and mechanisms of tumor stem cells in HER2-positive breast cancer treatment resistance (Review)	5
Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer	5
[Corrigendum] miR‑382 inhibits breast cancer progression and metastasis by affecting the M2 polarization of tumor‑associated macrophages by targeting PGC‑1α	5
uPAR, beyond regulating physiological functions, has orchestrated roles in cancer (Review)	5
IGJ suppresses breast cancer growth and metastasis by inhibiting EMT via the NF‑κB signaling pathway	5
CHCHD2 mediates glioblastoma cell proliferation, mitochondrial metabolism, hypoxia‑induced invasion and therapeutic resistance	5
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis	5
Role of the microbiome in systemic therapy for pancreatic ductal adenocarcinoma (Review)	5
Regulation of temozolomide resistance via lncRNAs: Clinical and biological properties of lncRNAs in gliomas (Review)	5
Long non‑coding RNA CASC11 interacts with YBX1 to promote prostate cancer progression by suppressing the p53 pathway	5
N⁶‑methyladenosine‑induced long non‑coding RNA PVT1 regulates the miR‑27b‑3p/BLM axis to promote prostate cancer progression	5
Transfusion‑related immunomodulation in patients with cancer: Focus on the impact of extracellular vesicles from stored red blood cells (Review)	5
Targeting PIM2 by JP11646 results in significant antitumor effects in solid tumors	5
RRM1 is mediated by histone acetylation through gemcitabine resistance and contributes to invasiveness and ECM remodeling in pancreatic cancer	5
Chromobox proteins in cancer: Multifaceted functions and strategies for modulation (Review)	5
New insight into the role of PTCH1 protein in serous ovarian carcinomas	5
Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients	5
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis	5
A novel lncRNA 495810 promotes the aerobic glycolysis in colorectal cancer by stabilizing pyruvate kinase isozyme M2	5
Hesperetin induces apoptosis in A549 cells via the Hsp70‑mediated activation of Bax	5
RNA m6A methylation regulators in endometrial cancer (Review)	5
Activated KRAS reprograms neural progenitor cells to glioma stem cell‑like phenotype	4
BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling pathway	4
Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)	4
Pan‑cancer analyses reveal the regulation and clinical outcome association of PCLAF in human tumors	4
The important regulatory roles of circRNA‑encoded proteins or peptides in cancer pathogenesis (Review)	4
Synergism of a novel MCL‑1 downregulator, acriflavine, with navitoclax (ABT‑263) in triple‑negative breast cancer, lung adenocarcinoma and glioblastoma multiforme	4
α‑hederin overcomes hypoxia‑mediated drug resistance in colorectal cancer by inhibiting the AKT/Bcl2 pathway	4
Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy	4
Chimeric HDAC and the cytoskeleton inhibitor broxbam as a novel therapeutic strategy for liver cancer	4
Antagonism of the transient receptor potential melastatin‑2 channel leads to targeted antitumor effects in primary human malignant melanoma cells	4
MELK predicts poor prognosis and promotes metastasis in esophageal squamous cell carcinoma via activating the NF‑κB pathway	4