OOIR: Observatory of International Research

Papers

(The TQCC of Brain Pathology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The 2021 WHO Classification of Tumors of the Central Nervous System: An update on pediatric low‐grade gliomas and glioneuronal tumors	105
COVID‐19‐related neuropathology and microglial activation in elderly with and without dementia	81
SARS‐CoV‐2 and the brain: A review of the current knowledge on neuropathology in COVID‐19	77
Classification of adult‐type diffuse gliomas: Impact of the World Health Organization 2021 update	69
The microbiota–microglia axis in central nervous system disorders	62
Brain ischemic injury in COVID‐19‐infected patients: a series of 10 post‐mortem cases	58
The role of interferons type I, II and III in myositis: A review	56
Microglia activation in postmortem brains with schizophrenia demonstrates distinct morphological changes between brain regions	56
Chronic sleep deprivation altered the expression of circadian clock genes and aggravated Alzheimer's disease neuropathology	52
Mediators of cerebral hypoperfusion and blood‐brain barrier leakiness in Alzheimer’s disease, vascular dementia and mixed dementia	51
Intracranial mesenchymal tumor with FET‐CREB fusion—A unifying diagnosis for the spectrum of intracranial myxoid mesenchymal tumors and angiomatoid fibrous histiocytoma‐like neoplasms	48
Pathological changes within the cerebral vasculature in Alzheimer’s disease: New perspectives	46
Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer’s disease	40
Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease	38
Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond	38
MRI and muscle imaging for idiopathic inflammatory myopathies	38
Glycocalyx is critical for blood‐brain barrier integrity by suppressing caveolin1‐dependent endothelial transcytosis following ischemic stroke	37
Interaction of microglia with infiltrating immune cells in the different phases of stroke	36
Tumor cell and immune cell profiles in primary human glioblastoma: Impact on patient outcome	35
The spectrum of rare central nervous system (CNS) tumors with EWSR1‐non‐ETS fusions: experience from three pediatric institutions with review of the literature	33
Prognostic impact of genetic alterations and methylation classes in meningioma	32
TREM2‐induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology	29
Infective myositis	29
Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change and microvascular pathologies in community‐dwelling older persons	28
Glutamatergic receptor expression changes in the Alzheimer's disease hippocampus and entorhinal cortex	28

Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders	26
Toward a refined genotype–phenotype classification scheme for the international consensus classification of Focal Cortical Dysplasia	26
Postmortem neuropathology in COVID‐19	25
Hypothesis review: Alzheimer's overture guidelines	25
Ependymoma‐like tumor with mesenchymal differentiation harboring C11orf95‐NCOA1/2 or ‐RELA fusion: A hitherto unclassified tumor related to ependymoma	24
Detection and quantification of novel C‐terminal TDP‐43 fragments in ALS‐TDP	24
Isoform‐specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias	23
The use and limitations of single‐cell mass cytometry for studying human microglia function	23
A deep learning‐based model for prediction of hemorrhagic transformation after stroke	21
Mitochondrial DNA variants in inclusion body myositis characterized by deep sequencing	21
Accumulation of cellular prion protein within β‐amyloid oligomer plaques in aged human brains	20
Effect of olfactory bulb pathology on olfactory function in normal aging	19
Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup	19
Proteomic analysis of human hippocampal subfields provides new insights into the pathogenesis of Alzheimer’s disease and the role of glial cells	19
Diverse changes in microglia morphology and axonal pathology during the course of 1 year after mild traumatic brain injury in pigs	18
Aged Tmem106b knockout mice display gait deficits in coincidence with Purkinje cell loss and only limited signs of non‐motor dysfunction	18
The fate of interneurons, GABA_A receptor sub‐types and perineuronal nets in Alzheimer's disease	18
Fibrinogen in the glioblastoma microenvironment contributes to the invasiveness of brain tumor‐initiating cells	18
Glial activation in prion diseases is selectively triggered by neuronal PrP^Sc	18
Distinct circular RNA expression profiles in pediatric ependymomas	18
Extralysosomal cathepsin B in central nervous system: Mechanisms and therapeutic implications	18
Inflammatory features in sporadic late‐onset nemaline myopathy are independent from monoclonal gammopathy	17
Identification of inflammasome signaling proteins in neurons and microglia in early and intermediate stages of Alzheimer's disease	17
The epigenetic mechanisms involved in mitochondrial dysfunction: Implication for Parkinson’s disease	17
Multiple system atrophy variant with severe hippocampal pathology	17
Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: An immunohistochemical analysis in autopsy cases including cases treated with aggressive a	17
Contribution of the astrocytic tau pathology to synapse loss in progressive supranuclear palsy and corticobasal degeneration	16
Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies	16
An integrative histopathological and epigenetic characterization of primary intracranial mesenchymal tumors, FET:CREB‐fused broadening the spectrum of tumor entities in comparison with their soft tiss	16
The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome	16
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three‐dimensional matrix	16
Cognitive decline in amyotrophic lateral sclerosis: Neuropathological substrate and genetic determinants	15
Oligodendrocyte‐specific deletion of FGFR2 ameliorates MOG_35‐55‐induced EAE through ERK and Akt signalling	15
NanoString technology distinguishes anti‐TIF‐1γ⁺ from anti‐Mi‐2⁺ dermatomyositis patients	15
Clinical implementation of integrated molecular‐morphologic risk prediction for meningioma	14
Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post‐mortem motor cortex and cerebrospinal fluid	14
Integrated genotype–phenotype analysis of long‐term epilepsy‐associated ganglioglioma	14
Molecular diagnostics in drug‐resistant focal epilepsy define new disease entities	14
Inactivation of the CB₂ receptor accelerated the neuropathological deterioration in TDP‐43 transgenic mice, a model of amyotrophic lateral sclerosis	14
Variability in the type and layer distribution of cortical Aβ pathology in familial Alzheimer’s disease	14
Muscle pathology of antisynthetase syndrome according to antibody subtypes	14
Downregulated GPR30 expression in the epileptogenic foci of female patients with focal cortical dysplasia type IIb and tuberous sclerosis complex is correlated with ¹⁸F‐FDG PET‐CT values	13
A novel temporal‐predominant neuro‐astroglial tauopathy associated with TMEM106B gene polymorphism in FTLD/ALS‐TDP	13
Association of CD2AP neuronal deposits with Braak neurofibrillary stage in Alzheimer’s disease	13
Focal cortical dysplasia type 1	13
Motor neuron involvement expands the neuropathological phenotype of late‐onset ataxia in RFC1 mutation (CANVAS)	13
Intracranial mesenchymal tumors with FET‐CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas	13
Embryonal and non‐meningothelial mesenchymal tumors of the central nervous system – Advances in diagnosis and prognostication	13
Alpha‐synuclein‐associated changes in PINK1‐PRKN‐mediated mitophagy are disease context dependent	13
Molecular neuropathology of brain‐invasive meningiomas	12

Region‐specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1	12
Targeting the interaction of GABA_B receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse br	12
Overexpression of the ubiquitin‐editing enzyme A20 in the brain lesions of Multiple Sclerosis patients: moving from systemic to central nervous system inflammation	12
Axonal injury following mild traumatic brain injury is exacerbated by repetitive insult and is linked to the delayed attenuation of NeuN expression without concomitant neuronal death in the mouse	12
Genomic profiling and prognostic factors of H3 K27M‐mutant spinal cord diffuse glioma	11
Impact of α‐synuclein spreading on the nigrostriatal dopaminergic pathway depends on the onset of the pathology	11
Use of advanced neuroimaging and artificial intelligence in meningiomas	11
Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress	11
Expanding the spectrum of EWSR1‐PATZ1 rearranged CNS tumors: An infantile case with leptomeningeal dissemination	11
Deciphering the heterogeneity of myeloid cells during neuroinflammation in the single‐cell era	11
Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer’s and small vessel disease pathologies	11
Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1^G93A mouse model of amyotrophic later	10
Monomeric C‐reactive protein: A novel biomarker predicting neurodegenerative disease and vascular dysfunction	10
Molecular landscape of IDH‐wild type, pTERT‐wild type adult glioblastomas	10
Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP	10
CNS inflammation after natalizumab therapy for multiple sclerosis: A retrospective histopathological and CSF cohort study	10
Automated and unbiased discrimination of ALS from control tissue at single cell resolution	9
The neurovasculature as a target in temporal lobe epilepsy	9
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis	9
Brain‐specific loss of Abcg1 disturbs cholesterol metabolism and aggravates pyroptosis and neurological deficits after traumatic brain injury	9
Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficits	9
Does etiology really matter for epilepsy surgery outcome?	9
Alleviation of extensive visual pathway dysfunction by a remyelinating drug in a chronic mouse model of multiple sclerosis	9
Endoplasmic reticulum‐stress and unfolded protein response‐activation in immune‐mediated necrotizing myopathy	9
Deficiency of Tet3 in nucleus accumbens enhances fear generalization and anxiety‐like behaviors in mice	9
TDP‐43 and tau concurrence in the entorhinal subfields in primary age‐related tauopathy and preclinical Alzheimer's disease	9
IDH‐mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature	9
lncRNA MEG3 restrained the M1 polarization of microglia in acute spinal cord injury through the HuR/A20/NF‐κB axis	8
The influence of HLA‐DRB115* on the relationship between microglia and neurons in multiple sclerosis normal appearing cortical grey matter	8
Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult	8
Aβ plaques do not protect against HSV‐1 infection in a mouse model of familial Alzheimer's disease, and HSV‐1 does not induce Aβ pathology in a model of late onset Alzheimer's di	8
Prognostic relevance of adding MRI data to WHO 2016 and cIMPACT‐NOW updates for diffuse astrocytic tumors in adults. Working toward the extended use of MRI data in integrated glioma diagnosis	8
Application of deep learning to understand resilience to Alzheimer's disease pathology	8
Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain	8
Application of single cell genomics to focal epilepsies: A call to action	8