OOIR: Observatory of International Research

Papers

(The TQCC of Brain Pathology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
	171
Issue Information	121
Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis	95
Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease	85
A 29‐year‐old man with a right intracranial mass	63
Reply to letter by Melmed et al.	61
Issue Information	54
Left dural‐based mass in a 62‐year‐old female	45
Issue Information	41
Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1^G93A mouse model of amyotrophic later	38
	33
Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis	32
Intraventricular mass in a 49‐year‐old male	32
Tumor‐associated astrocytes promote tumor progression of Sonic Hedgehog medulloblastoma by secreting lipocalin‐2	31
Astrocyte‐derived Interleukin‐31 causes poor prognosis in elderly patients with intracerebral hemorrhage	31
Human amygdala involvement in Alzheimer's disease revealed by stereological and dia‐PASEF analysis	30
Pathologic TDP‐43 downregulates myelin gene expression in the monkey brain	29
	28
A 76‐year‐old male with multiple enhancing brain lesions	27
Issue Information	26
The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system	26
Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype	25
40‐Year‐old man with two asynchronous spinal cord tumors	24
Cerebellar structural, astrocytic, and neuronal abnormalities in the SMNΔ7 mouse model of spinal muscular atrophy	24
Progress in stratified stroke characterization—associated with better diagnosis, accurate prognosis and improved treatment strategies	23

A 55‐year‐old man with a cerebral mass	22
Molecular neuropathology of brain‐invasive meningiomas	22
Dendritic location of dystrophic neurites in FTLD‐TDP type C with annexinopathy	21
Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study	20
Visualizing alpha‐synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo	20
Issue Information	19
Epilepsy‐associated death in the Southwestern Ontario: A clinicopathological correlation study	19
The pontine diffuse midline glioma, EGFR‐subtype with ependymal features: Yet another face of diffuse midline glioma, H3K27‐altered	18
Issue Information	18
A posterior fossa mass in a 4‐year‐old female	18
Potentiating microglial efferocytosis by MFG‐E8 improves survival and neurological outcome after successful cardiopulmonary resuscitation in mice	16
Embryonal and non‐meningothelial mesenchymal tumors of the central nervous system – Advances in diagnosis and prognostication	16
Prognostic impact of genetic alterations and methylation classes in meningioma	16
Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders	15
Neurofilament light chain as a marker of peripheral nerve damage in vasculitic neuropathy? A cross‐compartmental correlation analysis in patients undergoing nerve biopsy	15
	15
Clinico‐sero‐pathological characteristics of anti‐Ha antisynthetase syndrome	15
	15
The relation between BTK expression and iron accumulation of myeloid cells in multiple sclerosis	14
Refinement of prognostication for IDH‐mutant astrocytomas using DNA methylation‐based classification	14
Colocalization of TDP‐43 and stress granules at the early stage of TDP‐43 aggregation in amyotrophic lateral sclerosis	14
Selective neurodegeneration generated by intravenous α‐synuclein pre‐formed fibril administration is not associated with endogenous α‐synuclein levels in the rat brain	14
Issue Information	14
Genomic profiling and prognostic factors of H3 K27M‐mutant spinal cord diffuse glioma	14
Issue Information	14
Society News	13
NAB2::STAT6 fusions and genome‐wide DNA methylation profiling: Predictors of patient outcomes in meningeal solitary fibrous tumors	13
Muscle pathology of antisynthetase syndrome according to antibody subtypes	13
Issue Information	13
Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain	13
Primary visual cortex pathology in ALS patients with C9ORF72 expansion	13
SOCIETY NEWS	13
Issue Information	13
LAMP‐2A ablation in hippocampal CA1 astrocytes confers cerebroprotection and ameliorates neuronal injury after global brain ischemia	13
A role for vessel‐associated extracellular matrix proteins in multiple sclerosis pathology	12
Upregulation of sphingomyelin and ABCA8 in response to TDP ‐43 pathology in amyotrophic lateral sc	12
	12
Did early studies of human traumatic brain injury overlook concomitant oligodendrocyte pathology in injured white matter tracts? A comment on “Detection and verification of neurodegeneration after tra	12
Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival	12
Paul Kleihues (1936–2022), neuropathology innovator and entrepreneur	12
Monomeric C‐reactive protein: A novel biomarker predicting neurodegenerative disease and vascular dysfunction	11
Dysregulation of the renin‐angiotensin system in vascular dementia	11
Molecular landscape of IDH‐wild type, pTERT‐wild type adult glioblastomas	11
Brain‐specific loss of Abcg1 disturbs cholesterol metabolism and aggravates pyroptosis and neurological deficits after traumatic brain injury	11
Differential perivascular microglial activation in the deep white matter in vascular dementia developed post‐stroke	11
Nitro‐oleic acid activation of endothelial PPARγ signaling pathway alleviates neurovascular injury and improves functional outcomes in ischemic stroke	10
Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy	10
Inorganic phosphate exporter heterozygosity in mice leads to brain vascular calcification, microangiopathy, and microgliosis	10
	10
Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis	10

Issue Information	10
Multiple intracranial hemorrhages in a postmenopausal female	10
A 4‐year‐old boy with a ventricular mass	9
An 11‐year‐old boy with a posterior fossa tumor	9
Poly‐GA immunohistochemistry is a reliable tool for detecting C9orf72 hexanucleotide repeat expansions	9
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis	9
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy	9
A 24‐year‐old woman with a recurrent intracranial mass	9
Issue Information	9
Deep learning‐based segmentation in MRI‐(immuno)histological examination of myelin and axonal damage in normal‐appearing white matter and white matter hyperintensities	9
A vade mecum for crossing the second translational “valley of death” in brain tumor classification	9
Reduced neurogenesis in human hippocampus with Alzheimer's disease	8
Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation	8
Targeting the interaction of GABA_B receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse br	8
Single‐nucleus RNA sequencing unveils critical regulators in various hippocampal neurons for anti‐N‐methyl‐D‐aspartate receptor encephalitis	8
Foxq1 activates CB2R with oleamide to alleviate POCD	8
Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: An immunohistochemical analysis in autopsy cases including cases treated with aggressive a	8
Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.	8
A 31‐year‐old man with recurrent blurred vision	7
Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP	7
Ranking and filtering of neuropathology features in the machine learning evaluation of dementia studies	7
cIMPACT‐NOW update 11: Proposal on adaptation of diagnostic criteria for IDH‐ and H3‐wildtype diffuse high‐grade gliomas and for posterior fossa ependymal t	7
LATE‐NC in Alzheimer's disease: Molecular aspects and synergies	7
Cortical iron accumulation in MAPT‐ and C9orf 72‐associated frontotemporal lobar degeneration	7
Hippo pathway effectors are associated with glioma patient survival, control cell proliferation and sterol metabolism through TEAD3	7