Brain Pathology

Article	Citations
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Intraventricular mass in a 49‐year‐old male	93
An 82‐year‐old man with a right frontal lobe rim‐enhancing lesion	83
Tumor‐associated astrocytes promote tumor progression of Sonic Hedgehog medulloblastoma by secreting lipocalin‐2	69
Pathologic TDP‐43 downregulates myelin gene expression in the monkey brain	52
A 29‐year‐old man with a right intracranial mass	51
Reply to letter by Melmed et al.	49
Issue Information	40
Left dural‐based mass in a 62‐year‐old female	39
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Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis	30
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Astrocyte‐derived Interleukin‐31 causes poor prognosis in elderly patients with intracerebral hemorrhage	28
Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease	26
Human amygdala involvement in Alzheimer's disease revealed by stereological and dia‐PASEF analysis	26
Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1G93A mouse model of amyotrophic later	26
Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis	26
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The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system	25
Dendritic location of dystrophic neurites in FTLD‐TDP type C with annexinopathy	24
Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype	23
Molecular neuropathology of brain‐invasive meningiomas	23
A 76‐year‐old male with multiple enhancing brain lesions	23

Visualizing alpha‐synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo	22
Cerebellar structural, astrocytic, and neuronal abnormalities in the SMNΔ7 mouse model of spinal muscular atrophy	22
Issue Information	21
The pontine diffuse midline glioma, EGFR‐subtype with ependymal features: Yet another face of diffuse midline glioma, H3K27‐altered	20
40‐Year‐old man with two asynchronous spinal cord tumors	20
A 55‐year‐old man with a cerebral mass	20
Progress in stratified stroke characterization—associated with better diagnosis, accurate prognosis and improved treatment strategies	20
A posterior fossa mass in a 4‐year‐old female	19
Embryonal and non‐meningothelial mesenchymal tumors of the central nervous system – Advances in diagnosis and prognostication	18
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Epilepsy‐associated death in the Southwestern Ontario: A clinicopathological correlation study	18
Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders	17
Potentiating microglial efferocytosis by MFG‐E8 improves survival and neurological outcome after successful cardiopulmonary resuscitation in mice	16
Prognostic impact of genetic alterations and methylation classes in meningioma	16
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Society News	14
Lumbar spine intrathecal transplantation of neural precursor cells promotes oligodendrocyte proliferation in hot spots of chronic demyelination	14
Selective neurodegeneration generated by intravenous α‐synuclein pre‐formed fibril administration is not associated with endogenous α‐synuclein levels in the rat brain	14
Colocalization of TDP‐43 and stress granules at the early stage of TDP‐43 aggregation in amyotrophic lateral sclerosis	14
Clinico‐sero‐pathological characteristics of anti‐Ha antisynthetase syndrome	14
Primary visual cortex pathology in ALS patients with C9ORF72 expansion	13
Issue Information	13
Refinement of prognostication for IDH‐mutant astrocytomas using DNA methylation‐based classification	13
A 2‐year‐old girl with posterior fossa mass	13
Genomic profiling and prognostic factors of H3 K27M‐mutant spinal cord diffuse glioma	13
Society News	12
Issue Information	12
NAB2::STAT6 fusions and genome‐wide DNA methylation profiling: Predictors of patient outcomes in meningeal solitary fibrous tumors	12
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SOCIETY NEWS	11
LAMP‐2A ablation in hippocampal CA1 astrocytes confers cerebroprotection and ameliorates neuronal injury after global brain ischemia	11
Issue Information	11
The relation between BTK expression and iron accumulation of myeloid cells in multiple sclerosis	11
Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain	11
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Did early studies of human traumatic brain injury overlook concomitant oligodendrocyte pathology in injured white matter tracts? A comment on “Detection and verification of neurodegeneration after tra	10
Muscle pathology of antisynthetase syndrome according to antibody subtypes	10
A role for vessel‐associated extracellular matrix proteins in multiple sclerosis pathology	10
Brain‐specific loss of Abcg1 disturbs cholesterol metabolism and aggravates pyroptosis and neurological deficits after traumatic brain injury	10
Differential perivascular microglial activation in the deep white matter in vascular dementia developed post‐stroke	9
Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival	9
A 4‐year‐old boy with a ventricular mass	9
Inorganic phosphate exporter heterozygosity in mice leads to brain vascular calcification, microangiopathy, and microgliosis	9
Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis	9
Molecular landscape of IDH‐wild type, pTERT‐wild type adult glioblastomas	9
Intracranial mesenchymal tumors with FET‐CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas	9
Paul Kleihues (1936–2022), neuropathology innovator and entrepreneur	9
Dysregulation of the renin‐angiotensin system in vascular dementia	9

Monomeric C‐reactive protein: A novel biomarker predicting neurodegenerative disease and vascular dysfunction	9
Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy	9
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Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.	8
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Association of CD2AP neuronal deposits with Braak neurofibrillary stage in Alzheimer’s disease	8
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis	8
Deep learning‐based segmentation in MRI‐(immuno)histological examination of myelin and axonal damage in normal‐appearing white matter and white matter hyperintensities	8
Poly‐GA immunohistochemistry is a reliable tool for detecting C9orf72 hexanucleotide repeat expansions	8
Nitro‐oleic acid activation of endothelial PPARγ signaling pathway alleviates neurovascular injury and improves functional outcomes in ischemic stroke	8
Multiple intracranial hemorrhages in a postmenopausal female	8
Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation	8
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy	8
Issue Information	8
A vade mecum for crossing the second translational “valley of death” in brain tumor classification	8
Foxq1 activates CB2R with oleamide to alleviate POCD	7
Single‐nucleus RNA sequencing unveils critical regulators in various hippocampal neurons for anti‐N‐methyl‐D‐aspartate receptor encephalitis	7
Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP	7
LATE‐NC in Alzheimer's disease: Molecular aspects and synergies	7
Targeting the interaction of GABAB receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse br	7
Ranking and filtering of neuropathology features in the machine learning evaluation of dementia studies	7
A 24‐year‐old woman with a recurrent intracranial mass	7
Reduced neurogenesis in human hippocampus with Alzheimer's disease	7
Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: An immunohistochemical analysis in autopsy cases including cases treated with aggressive a	7
An 11‐year‐old boy with a posterior fossa tumor	7
Cortical iron accumulation in MAPT‐ and C9orf 72‐associated frontotemporal lobar degeneration	6
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Hippo pathway effectors are associated with glioma patient survival, control cell proliferation and sterol metabolism through TEAD3	6
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Understanding the pathogenic mechanisms and therapeutic effects in neurocysticercosis	6
A 31‐year‐old man with recurrent blurred vision	6
Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation	6
Concomitant progressive supranuclear palsy and Lewy body pathology presenting with circumscribed visual memory loss: A clinicopathological case	6
Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke	6
Society News	6
cIMPACT‐NOW update 11: Proposal on adaptation of diagnostic criteria for IDH‐ and H3‐wildtype diffuse high‐grade gliomas and for posterior fossa ependymal t	6
CHCHD2 p.Thr61Ile knock‐in mice exhibit motor defects and neuropathological features of Parkinson's disease	6
Morphology‐based molecular classification of spinal cord ependymomas using deep neural networks	6
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The fate of interneurons, GABAA receptor sub‐types and perineuronal nets in Alzheimer's disease	5
Issue Information	5
Alzheimer's disease phenotype based upon the carrier status of the apolipoprotein E ɛ4 allele	5
Dynamic induction of the myelin‐associated growth inhibitor Nogo‐A in perilesional plasticity regions after human spinal cord injury	5
Society News	5
Friends or foes: The mononuclear phagocyte system in ischemic stroke	5
Automated analysis of gray matter damage in aged mice reveals impaired remyelination in the cuprizone model	5
Differential expression of checkpoint markers in the normoxic and hypoxic microenvironment of glioblastomas	5
Quantitative magnetic resonance imaging reflects different levels of histologically determined myelin densities in multiple sclerosis, including remyelination in inactive multiple sclerosis lesions	5
Society News	5
A 16‐year‐old female with an intrasellar mass	5
Clinical, neuropathological, and immunological short‐ and long‐term feature of a mouse model mimicking human herpes virus encephalitis	5
Inflammatory and oxidative stress markers in intracerebral hemorrhage: Relevance as prognostic markers for quantification of the edema volume	5
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Increased expression of human antiviral protein MxA in FUS proteinopathy in amyotrophic lateral sclerosis	4
Society News	4
A 3‐year‐old male with an extramedullary, intra‐ and extradural mass at T11‐L1	4
Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies	4
The post‐stroke young adult brain has limited capacity to re‐express the gene expression patterns seen during early postnatal brain development	4
The WHO classification of tumors of the central nervous system‐finally here, and welcome!	4
A 63‐year‐old woman with parietal scalp surface rugged	4
Somatostatin receptors in pituitary somatotroph adenomas as predictors of response to somatostatin receptor ligands: A pathologist's perspective	4
Multi‐pronged analysis of pediatric low‐grade glioma and ganglioglioma reveals a unique tumor microenvironment associated with BRAF alterations	4
Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection	4
A comprehensive histomolecular characterization of meningioangiomatosis: Further evidence for a precursor neoplastic lesion	4
The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome	4
TDP‐43 and tau concurrence in the entorhinal subfields in primary age‐related tauopathy and preclinical Alzheimer's disease	3
Exploiting nanopore sequencing for characterization and grading of IDH‐mutant gliomas	3
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A young man with multifocal brainstem leptomeningeal disease	3
A tribute to John Q. Trojanowski (1946–2022), neuropathologist extraordinaire	3
Studying the imaging features and infarction mechanism of vertebrobasilar dolichoectasia with high‐resolution magnetic resonance imaging	3
Neuropathological stage‐dependent proteome mapping of the olfactory tract in Alzheimer's disease: From early olfactory‐related omics signatures to computational repurposing of drug candidat	3
Nanoarchitecture of CaV2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology	3
Hypothesis review: Alzheimer's overture guidelines	3
A new amplicon‐based gene panel for next generation sequencing characterization of meningiomas	3
Design and application of a customizable relational DataBase to assess clinicopathological correlations and concomitant pathology in neurodegenerative diseases	3
Present and future avenues of cell‐based therapy for brain injury: The enteric nervous system as a potential cell source	3
Information theory approaches to improve glioma diagnostic workflows in surgical neuropathology	3
Decreased microvascular claudin‐5 levels in cerebral amyloid angiopathy associated with intracerebral haemorrhage	2
Developmental delay and progressive seizures in 2‐month‐old child with diffuse MRI abnormalities	2

Society News	2
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A 7‐year‐old boy presented with temporal lobe lesion	2
Acknowledgement to Reviewers	2
Enhanced Creutzfeldt‐Jakob disease surveillance in the older population: Assessment of a protocol for screening brain tissue donations for prion disease	2
Brain heterotopia formation by ciliopathic breakdown of neuroepithelial and blood‐cerebrospinal fluid barriers	2
Temporal lobe myxoid glioneuronal tumor, PDGFRA p.K385L‐mutant with DNA methylation confirmation	2
The influence of HLA‐DRB1*15 on the relationship between microglia and neurons in multiple sclerosis normal appearing cortical grey matter	2
The molecular history of IDH‐mutant astrocytomas without adjuvant treatment	2
Recurrent TRAK1::RAF1 Fusions in pediatric low‐grade gliomas	2
Two novel tumours with NTRK2 fusion in the methylation class of extraventricular neurocytomas, including one intraventricular	2
Proteomic analysis identifies HSP90AA1, PTK2B, and ANXA2 in the human entorhinal cortex in Alzheimer's disease: Potential role in synaptic homeos	2
Author Index	2
The 2021 WHO Classification of Tumors of the Central Nervous System: An update on pediatric low‐grade gliomas and glioneuronal tumors	2
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IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS‐associated amyotrophic lateral sclerosis	2
Targeting autotaxin impacts disease advance in the SOD1‐G93A mouse model of amyotrophic lateral sclerosis	2
Extralysosomal cathepsin B in central nervous system: Mechanisms and therapeutic implications	2
Pathology explains various mechanisms of auto‐immune inflammatory peripheral neuropathies	2
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Report two adult cases of high‐grade neuroepithelial neoplasm harbouring EP300::BCOR fusions with comprehensive molecular detection	2
Extra‐axial mass in a 72‐year‐old woman	2
Krüppel‐like factor 7 deficiency disrupts corpus callosum development and neuronal migration in the developing mouse cerebral cortex	2
Issue Information	2
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Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation	2
Society News	2
Aβ plaques do not protect against HSV‐1 infection in a mouse model of familial Alzheimer's disease, and HSV‐1 does not induce Aβ pathology in a model of late onset Alzheimer's di	2
Microvessel stenosis, enlarged perivascular spaces, and fibrinogen deposition are associated with ischemic periventricular white matter hyperintensities	1
A 7‐year‐old female with hypotonia and scoliosis	1
cIMPACT‐NOW update 10: Recommendations for defining new types for central nervous system tumor classification	1
Axonal injury following mild traumatic brain injury is exacerbated by repetitive insult and is linked to the delayed attenuation of NeuN expression without concomitant neuronal death in the mouse	1
MET fusions and splicing variants is a strong adverse prognostic factor in astrocytoma, isocitrate dehydrogenase mutant	1
Perivascular phosphorylated TDP‐43 inclusions are associated with Alzheimer's disease pathology and loss of CD146 and Aquaporin‐4	1
Felice Giangaspero—A man of style and substance	1
Correspondence to: Clinico‐sero‐pathological characteristics of anti‐Ha antisynthetase syndrome	1
Functionally distinct pericyte subsets differently regulate amyloid‐β deposition in patients with Alzheimer's disease	1
Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond	1
Meeting report of the 20th International Congress of Neuropathology (ICN) 2023 in Berlin	1
Sterol imbalances and cholesterol‐24‐hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis	1
Altered properties of amyloidogenic prion protein in genetic Creutzfeldt–Jakob disease with PRNP V180I mutation in response to pentosan polysulfate	1
Proteomic analysis of human hippocampal subfields provides new insights into the pathogenesis of Alzheimer’s disease and the role of glial cells	1
Multiple system atrophy with hippocampal pathology	1
Contribution of whole slide imaging‐based deep learning in the assessment of intraoperative and postoperative sections in neuropathology	1
Histamine in murine narcolepsy: What do genetic and immune models tell us?	1
A mass in the pineal region of a young woman	1
Variable histopathology features of neuronal dyslamination in the cerebral neocortex adjacent to epilepsy‐associated vascular malformations suggest complex pathogenesis of focal cortical dysplasia ILA	1
Correction to “A 4‐year‐old boy with a ventricular mass”	1
Detection and verification of neurodegeneration after traumatic brain injury in the mouse: Immunohistochemical staining for amyloid precursor protein	1
Stereological analysis of cholinergic neurons within bilateral pedunculopontine nuclei in health and when affected by Parkinson's disease	1
A 53‐year‐old woman with a 16‐year history of epilepsy	1
Society News	1
Comparing GBA1‐Parkinson's disease and idiopathic Parkinson's disease: α‐Synuclein oligomers and synaptic density as biomarkers in the skin biopsy	1
The prevalence of chronic traumatic encephalopathy in a historical epilepsy post‐mortem collection	1
Issue Information	1
Honing in on magnetic resonance imaging predictors of multiple sclerosis pathology	1
Nicorandil treatment improves survival and spatial learning in aged granulin knockout mice	1
Comparative pathology boards facilitate the translation of knowledge between canine and human cancer patients	1
Effect of olfactory bulb pathology on olfactory function in normal aging	1
AtypicalTDP‐43 protein expression in anALSpedigree carrying a p.Y374Xtruncation mutation inTARDBP	1
Introduction to the mini‐symposium “molecular neuropathology of meningioma”	1
Age‐related hearing loss and dementia‐related neuropathology: An analysis of the United Kingdom brains for dementia research cohort	1
A supratentorial mass in a young adult, with 25 years of follow‐up	1
Vascular endothelial growth factor‐C modulates cortical NMDA receptor activity in cortical lesions of young patients and rat model with focal cortical dysplasia	1
Severe histomorphological alterations in post‐mortem olfactory glomeruli in Alzheimer’s disease	1
Endoplasmic reticulum‐stress and unfolded protein response‐activation in immune‐mediated necrotizing myopathy	1
A diffuse glioma with oligodendroglial‐like cells and extensive calcifications	1
Society News	1
Society News	1
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