OOIR: Observatory of International Research

Papers

(The median citation count of Medical Principles and Practice is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Association between Body Composition and Chronic Low Back Pain in Korean Adults Aged over 50 Years: The Korea National Health and Nutrition Examination Survey (KNHANES) 2010–2011	62
Assessment of Blood Lead Levels in Pre-School Children in Kuwait	50
The Effect of Citric and Ascorbic Acids as Anti-Biofilm and Anti-Capsular Agents on Multidrug-Resistant <i>Acinetobacter baumannii</i>	37
Relative Importance of Defined Mycobacterium tuberculosis Antigens in the T-Cell Recognition Repertoire of Latently Infected Individuals Not Progressing to Active Disease	30
Letter regarding the Published Article “Evaluation of Aortic Elasticity Parameters in Survivors of COVID-19 Using Echocardiography Imaging”	30
The Impact of SARS-CoV-2 Infection in Unvaccinated Multiple Sclerosis Patients on Disease-Modifying Therapies	29
Front & Back Matter	28
Impact of Silver Dressings on Wound Healing Rate in Patients with Lower Extremity Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	22
Hypertension in Czech Adults Aged 25-64: Prevalence, Awareness, Control and Risk Factors in 2019 - A Cross-Sectional Study	20
Evaluation of the Relationship between CD44 Expression and Gleason Grade among Prostate Adenocarcinoma and Benign Prostatic Hyperplasia: A Cross-Sectional Study	20
COVID-19 and the Human Eye: Conjunctivitis, a Lone COVID-19 Finding – A Case-Control Study	19
COVID-19 Oral Sequelae: Persistent Gustatory and Saliva Secretory Dysfunctions after Recovery from COVID-19	19
Red Blood Cells and their Immunoregulatory Role	18
COVID-19: Acing the Treatment	16
Impact of Polycystic Ovary Syndrome on Periodontal Status of Women of Adolescent and Adult Age Groups: A Cross-Sectional Study	16
Retraction Statement	15
Reply to the Letter regarding the Published Article “Evaluation of Aortic Elasticity Parameters in Survivors of COVID-19 Using Echocardiography Imaging”	15
Description of Methicillin-Susceptible <b><i>Staphylococcus aureus</i></b> Clonal Complex 30 Related to the Pandemic Phage Type 80/81 Isolated from Patients in Three Tertiary H	15
The Dual Impact of Obesity and Diabetes on Heart Failure Readmissions: Results from the CHF Registry at Harlem Hospital Center	14
Nuclear Factor-κB Clinical Significance in Breast Cancer: An Immunohistochemical Study	13
Vasoconstrictor Effects of Trace Amine-Associated Receptor Agonists in the Isolated Perfused Rat Kidney	12
Evaluation of the CLL-IPI and IPS-E Prognostic Indices in a Young Middle Eastern Population with Chronic Lymphocytic Leukemia: A Retrospective Analysis at the Kuwait Cancer Control Center	12
Prevalence of Urinary Tract Infections and Antibiotic Susceptibility Patterns of Uropathogens among Neonates in Maternity Hospital, Kuwait: A Six-Year Retrospective Study	11
Curcumin Derivatives as Allosteric Modulator of α7-nAChR: Functional and Molecular Docking Insights	11
Increased Glucagon Immunoreactivity in a Rat Model of Diet-Induced Obesity following Sleeve Gastrectomy	11

Antibiotic Sensitivity of Group B Streptococcus from Pregnant Mothers and Its Association with Resistance Genes	11
Spatial Variations in the Nasal Microbiota of Staff Working in a Healthcare-Associated Research Core Facility	11
Detailed Analysis of Prognostic Factors in Patients with Soft Tissue Sarcoma Undergoing Unplanned Excision	10
The Modulation of Euglycemic Endocrine and Exocrine Pancreatic Secretions in Iron Deficiency	10
Evidence of Subclinical Visual Pathway Dysfunction in Polio Survivors: A Visual Evoked Potential Study	10
Use of Rituximab as an Off-Label Medication in Glomerular Diseases: Clinical Perspective	10
Comparative Evaluation of Clinical Efficacy of Leukocyte-Rich Platelet-Rich Fibrin with Advanced Platelet-Rich Fibrin in Management of Gingival Recession Defects: A Randomized Controlled Trial	10
The Gut in Heart Failure: Current Knowledge and Novel Frontiers	9
Telerehabilitation during the COVID-19 Pandemic: Patients and Physical Therapists’ Experiences	9
Biopsychosocial Factors and Pain Hypervigilance Should Be Considered in the Interpretation of Disease Activity in Systemic Sclerosis	9
Multiplex <b><i>gyrB</i></b> PCR Assay for Identification of <b><i>Acinetobacter baumannii</i></b> Is Validated by Whole Genome Sequence-Based Assays	9
Proinflammatory State in the Odontogenesis of Fetuses Exposed to Different Types of Fatty Acids during Pregnancy	9
A Discrepancy: Calcium Channel Blockers Are Effective for the Treatment of Hypertensive Left Ventricular Hypertrophy but Not as Effective for Prevention of Heart Failure	9
Efficacy of Drug Coated Balloon versus Drug Eluting Stent for Patients with De Novo Coronary Artery Disease: A Systematic Review and Meta-Analysis	8
The Role of Advanced Glycation End Products in Saphenous Vein Graft Failure	8
Comparative Bioavailability Study of Solid Self-Nanoemulsifying Drug Delivery System of Fenofibric Acid in Healthy Male Subjects	8
Front & Back Matter	8
The SCN5A Gene Is a Predictor of Phenotype Severity in Brugada Syndrome: A Comprehensive Literature Review	7
The Emerging Role of AI in Patient Education: A Comparative Analysis of the Accuracy of Large Language Models for Pelvic Organ Prolapse	7
Retraction Statement	7
Response to Letter on “Chronic Respiratory Diseases and Neurodegenerative Disorders: A Primer for the Practicing Clinician”	7
Response to Letter on “Clarifying the Role of the Kynurenine Pathway in Behçet’s Syndrome: A Commentary on Uçar et al.”	7
Comparison of BAP65, DECAF, PEARL, and MEWS Scores in Predicting Respiratory Support Need in Hospitalized Exacerbation of Chronic Obstructive Lung Disease Patients	7
Impact of Serotonin Pathway Gene Polymorphisms and Serotonin Levels in Suicidal Behaviour	6
Advancements in HLA Typing Techniques and Their Impact on Transplantation Medicine	6
Response to Letter on “The Death of Pyotr Ilyich Tchaikovsky: The Result of Treatment with Arsenic?”	6
Radiology in the Undergraduate Medical Curriculum: The Student Perspective	6
Incidence and Risk Factors of Left Ventricular Thrombus in Acute ST-Segment Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention: A Meta-Analysis	6
Clinicopathological Pattern of Nonmelanoma Skin Cancer in Kuwait: A Retrospective Study	6
Front & Back Matter	6
Vedolizumab: Beyond Inflammatory Bowel Disease	6
Association between RS Time in Electrocardiogram and Right Ventricular Functions in Patients with Chronic Obstructive Pulmonary Disease	6
FORTA Score and Negative Outcomes in Older Adults: Insights from Italian Internal Medicine Wards	6
Prevalence and Factors Associated with Olfactory Dysfunction in Individuals with COVID-19 in Brazil: A Study of 20,669 Cases from 2020 to 2021	6
Response to the Letter on “Plasma Sodium and Laboratory Parameters in Determining Complicated Appendicitis in Children”	5
Isolated Femoral or Tibial Component Revision in Total Knee Arthroplasty: A Systematic Review	5
The Value of Baseline Intact Parathyroid Hormone in Vitamin D Supplementation for Early Multiple Sclerosis	5
Immunological Profile of Patients with Rheumatoid Arthritis and Asthma	5
Efficacy and Safety of Glibenclamide on Functional Outcomes and Cerebral Edema following Ischemic and Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	5
Effect of Dual Glucagon-Like Peptide 1/Glucose-Dependent Insulinotropic Polypeptide Receptor Agonist (Tirzepatide) versus Bariatric Surgery on Weight Loss and Nonalcoholic Fatty Liver Disease	5
Potential Pitfalls of Steatopygia on Bone Scintigraphy and the Added Value of Single Photon Emission Computed Tomography and Single Photon Emission Computed Tomography/Computed Tomography	5
Cannabis-Related Cyclic/Episodic Hyperemesis Conditions: From Suspected to Definitive Cannabinoid Hyperemesis Syndrome	5
Whole-Cell and Acellular Pertussis Vaccine: Reflections on Efficacy	5
Clarifying the Role of the Kynurenine Pathway in Behçet’s Syndrome: A Commentary on Uçar et al.	5
List of Reviewers Vol. 31, 2022	4
Clinical Characteristics, Current Treatment Options, Potential Mechanisms, Biomarkers, and Therapeutic Targets in Avascular Necrosis of Femoral Head	4
Discordance in Phenotypic and Genotypic Susceptibility Testing for Streptomycin Due to Nonsynonymous/Nonsense/Deletion Frame-Shift Mutations in <i>gidB</i> among Clinical <i>Mycobact	4
The Predictive Value of Plasma Sodium and Other Laboratory Parameters in Determining Complicating Appendicitis in Children	4
Acetaminophen Has Lipid Composition-Dependent Membrane Interactivity That Could Be Related to Nephrotoxicity but Not to Analgesic Activity and Hepatotoxicity	4
The Prognostic Significance of Surgical Treatment for Excessive Elderly Soft Tissue Sarcoma Patients over 90 Years Old: A Clinicopathological Study of 16 Cases	4

Plasma Sodium and Laboratory Parameters in Determining Complicated Appendicitis in Children	4
Inhaled Aviptadil for Post-COVID Lung Injury: Early Promise, Future Directions	4
Letter on the Published Article “Chronic Respiratory Diseases and Neurodegenerative Disorders: A Primer for the Practicing Clinician”	4
Controlling Nutritional Status Score Predicts In-Hospital Mortality in Acute Pulmonary Embolism	4
The Effect of Delivery Systems on the Induction of T Helper 1 Cell Response to an ESAT6-Like Protein Rv3619c and Identification of Its Immunodominant Peptides	4
Acknowledgement to Reviewers	4
The Death of Pyotr Ilyich Tchaikovsky: The Result of Treatment with Arsenic?	4
Population Pharmacokinetics and Dose Optimization of Valganciclovir and Ganciclovir in Lung Transplant Recipients	4
SARS-CoV-2 Clinical Characteristics and Viral Shedding in Kuwait	4
Emergency Department and COVID-19 Pandemic Stress Test: A Comparison between Two European Settings	3
The Pediatric COVID-19 Registry in Kuwait: Methodology and Results of Pilot Phase	3
Risk Factors for Wound Infections after Vascular Surgery: Kuwait Experience	3
Diagnostic and Prognostic Performance of Plasma Albumin and Cholinesterase in Patients with Sepsis and Septic Shock	3
Effects of Apnea, Obesity, and Statin Therapy on Proprotein Convertase Subtilisin/Kexin 9 Levels in Patients with Obstructive Sleep Apnea	3
Comparison of Anxiety Levels with Salivary Cortisol Levels in Patients Undergoing Endodontic and Restorative Treatment	3
Systemic Statin Use and Pulp Chamber Calcification: A Pilot Retrospective Case-Control Study Using Cone-Beam Computed Tomography	3
Serum Levels of Plasminogen Activator Inhibitor-1 in Patients with Parkinson’s Disease	3
Selective Serotonin Reuptake Inhibitors and Risk of Serotonin Syndrome as Consequence of Drug-Drug Interactions: Analysis of the FDA Adverse Event Reporting System	3
The Impact of the COVID-19 Pandemic on Surgeons’ and Surgical Residents’ Caseload, Surgical Skills, and Mental Health in Kuwait	3
Contents Vol. 31, 2022	3
<i>Ganoderma lucidum</i> and <i>Hypericum perforatum</i> Exhibit Anti-Inflammatory, Antioxidant, and Anti-Androgen Effect in Rat Model of Experimental Polycystic Ovarian Syndro	3
The Effects and Outcomes of the COVID-19 Pandemic on Pregnant Women in Kuwait	3
High Incidence of Appendiceal Neoplasms in the Elderly: A Critical Concern for Non-Surgical Treatment	3
TCF7L2 and FTO Polymorphisms Are Associated with Type 2 Diabetes Mellitus Risk in Kuwait	3
Not Indolamine 2,3-Dioxygenase Polymorphisms, but Low Levels of Indoleamine 2,3-Dioxygenase and IDO2 Are Associated with Behçet’s Syndrome	3
Professor Naji Al-Zaid: An Obituary	3
Experience of Subcutaneous Levetiracetam in Palliative Care	3
Efficacy and Safety of Actinium-225 Prostate-Specific Membrane Antigen Radioligand Therapy in Metastatic Prostate Cancer: A Systematic Review and Metanalysis	3
Exploring Trends and Challenges in Global Health Dental Education: Scoping Review	3
Plasma Levels of Alpha and Gamma Synucleins in Children with Autism Spectrum Disorder: Statistical Validity	3
Front & Back Matter	3
Bioinformatics Analysis and Screening of Potential Target Genes Related to the Lung Cancer Prognosis	3
Effect of Chemotherapy in Stage II–IV Large-Cell Lung Carcinoma and Construction of Its Predictive Nomograms: A SEER Analysis	3
Reply to Letter “Cannabis-Related Cyclic/Episodic Hyperemesis Conditions: From Suspected to Definitive Cannabinoid Hyperemesis Syndrome”	3
Clinical Characteristics and Treatment Outcome of Central Nervous System Nocardiosis: A Systematic Review of Reported Cases	2
Assessment of Periodontal Status in Patients with Depression: A Cross-Sectional Study	2
Hepatocellular Carcinoma Subtyping and Prognostic Model Construction Based on Chemokine-Related Genes	2
The Mechanisms Associated with Inflammation and Coronary Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction	2
Poor Nutritional Status Is Associated with Arrhythmic Events on 24-Hour Holter Recording	2
National Institute of Health Stroke Scale (NIHSS) Scoring Tool Utilizing Medical Records: A Single-Center Validation Study	2
Pharmaceutical Polygon Fingerprinting Matrix System: A Potential Tool for Pharmaceutical Quality Control	2
Periconceptional supplementation with folic acid or multiple micronutrients containing folic acid and the risk for hypertensive disorders in pregnancy	2
Association of the Bioimpedance Phase Angle and Quality of Life in Postmenopausal Osteoporosis	2
COVID-19 in Dental Practice Is Prevented by Eugenol Responsible for the Ambient Odor Specific to Dental Offices: Possibility and Speculation	2
The Challenge of Hypophosphatasia Diagnosis in Patients with Fibromyalgia	2
The Emerging Role of AI in Patient Education: Correspondence	2
Cannabinoid Receptor Modulation in Focal Ischemic Stroke: A Systematic Review and Meta-Analysis of Infarct Volume and Behavioral Deficits in Animal Models	2
Clinical and Medical Economic Value of Screening Colonoscopy before Laparoscopic Cholecystectomy	2
Characteristics of Oral Adverse Effects following COVID-19 Vaccination and Similarities with Oral Symptoms in COVID-19 Patients: Taste and Saliva Secretory Disorders	2
Reference Genes for qPCR-Based miRNA Expression Profiling in 14 Human Tissues	2
Increased Circulating Copeptin Levels Are Associated with Vaso-Occlusive Crisis and Right Ventricular Dysfunction in Sickle Cell Anemia	2
Vitamin D Supplementation Mediates a Shift toward Anti-Inflammatory Cytokine Response in Multiple Sclerosis	2
Cannabis-Induced Gastrointestinal Tract Symptoms in the Adult Population: A Systematic Review	2
Long-Lasting Suppression of Mechanical Allodynia in Mice by Intrathecal Administration of an Anti-Cell Adhesion Molecule 1 Antibody	2
Mitochondrial Common Deletion Level in Adipose Tissue Is Not Associated with Obesity but Is Associated with a Structural Change in Triglycerides as Revealed by FTIR Spectroscopy	2
Reply to: “Qualitative Evaluation of α-Synuclein: A Critical Step in Unravelling the Complexities of Autism Spectrum Disorder”	2
Racial Discrimination and Multiple Health Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses	2
Outcome of Colorectal Robotic Surgery in Newly Established Robotic Surgery Center: A Case Series	2
Sex-Related Bleeding Risk in Acute Coronary Syndrome Patients Receiving Dual Antiplatelet Therapy with Aspirin and a P2Y12 Inhibitor	2
The Impact of Educational Status on the Occurrence of Colonic Diverticula: Insights from an Austrian Cohort Study	2
Retraction Statement	2
NSUN6 Regulates NM23-H1 Expression in an m5C Manner to Affect Epithelial-Mesenchymal Transition in Lung Cancer	2
A 60-Year Literature Review on Hepatic Actinomycosis	2
The Effects of Sodium-Glucose Cotransporter-2 Inhibitors on Implantable Cardioverter Defibrillator Shocks in Heart Failure Patients Undergoing Diuretic Therapy	1
Which Electronic Health Record System Should We Use? A Systematic Review	1
Epidemiology of de novo Acute Myeloid Leukemia in Kuwait per the 2016 WHO Classification	1
Unlocking Nitrofurantoin: Understanding Molecular Mechanisms of Action and Resistance in Enterobacterales	1
Factors Associated with a High-Risk Profile for Developing Pressure Injuries in Long-Term Residents of Nursing Homes	1
Risk Factors for Surgery in Pediatric Patients with Crohn’s Disease	1
Risk Factors for Mortality in Patients with COVID-19: The Kuwait Experience	1
The Role of Serum Galectin-3 Levels in Patients with Sarcoidosis	1
Predictive Value of Age, Creatinine, and Ejection Fraction I and II Scores for Postoperative Atrial Fibrillation in Isolated On-Pump Coronary Artery Bypass Grafting Surgery: A Multicenter Retrospectiv	1
Prognostic Value of Inflammation and Nutrition-Based Scores in Non-Small Cell Lung Cancer	1
Retrospective Cohort Study Comparing the Clinical Profile and Outcomes of Critically Ill Pregnant Patients in Kuwait during the COVID-19 Pandemic Waves	1
Acute Effect of Imeglimin Add-on Therapy on 24-h Glucose Profile and Glycemic Variability in Patients with Type 2 Diabetes Receiving Metformin	1
Acknowledgement to Reviewers	1
Alzheimer’s Disease: A Suitable Case for Treatment with Precision Medicine?	1
Response to Letter on “Inhaled Aviptadil for Post-COVID Lung Injury: Early Promise, Future Directions”	1
Inconsistency in the Application of Glasgow Coma Scale in Pediatric Patients	1
Response to the letter on “Vitamin D Supplementation Mediates a Shift toward Anti-Inflammatory Cytokine Response in Multiple Sclerosis”.	1

Ocular Surface, Intraocular Pressure, and Lens Condition in Bronchodilator and Steroid-Treated Patients with Chronic Pulmonary Disease	1
Comparison of Thyroid Uptake Values Measured from ¹³¹I Scintigraphy and Uptake Probe in Hyperthyroid Patients	1
Diagnostic Accuracy of Point-of-Care Testing of C-Reactive Protein, Interleukin-6, and Procalcitonin in Neonates with Clinically Suspected Sepsis: A Prospective Observational Study	1
Frequency and Predictors of Pulmonary Arterial Stump Thrombosis following Pneumonectomy or Lobectomy	1
The Role of Serum Resolvin D1 Levels in Determining the Presence and Prognosis of ST-Segment Elevation Myocardial Infarction	1
Thrombin Decrease in Thrombin Generation after Heparin Administration in a Homozygous Type II Heparin-Binding Site Antithrombin-Deficient Pregnant Woman	1
Prognostic Significance of Nuclear Factor Kappa B (p65) among Breast Cancer Patients in Cape Coast Teaching Hospital	1
Histamine Promotes Pseudomonas aeruginosa Biofilm Formation and Renders P. aeruginosa Biofilms More Resistant to Gentamicin and Azithromycin	1
The Potential of Bacteriophage Therapy as an Alternative Treatment Approach for Antibiotic-Resistant Infections	1
Dimple of Venus Is Associated with the Increased Pelvic Incidence Angle and More Sagittally Oriented Facet Joint	1
Does Sickle Cell Disease Protect against HIV Infection: A Systematic Review	1
IGFBP5 Promotes Neuronal Apoptosis in a 6-OHDA-Toxicant Model of Parkinson’s Disease by Inhibiting the Sonic Hedgehog Signaling Pathway	1
3D Printing in Dental Education: A Scoping Review	1
Takotsubo Syndrome Recurrence: A Trigger for Increased 30-Day Cardiovascular Mortality	1
Correlation between Physical Activity and Depression in Community-Dwelling Older Adult Palestinians	1
Reply: The Emerging Role of AI in Patient Education: A Comparative Analysis of the Accuracy of Large Language Models for Pelvic Organ Prolapse	1
Role of Cancer Side Population Stem Cells in Ovarian Cancer Angiogenesis	1
Friends and Foes in Alzheimer’s Disease	1