OOIR: Observatory of International Research

Papers

(The TQCC of Cell Research is 62. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
Ferroptosis: molecular mechanisms and health implications	1647
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy	420
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells	364
SARS-CoV-2 infects human neural progenitor cells and brain organoids	256
SARS-CoV-2 spike protein interacts with and activates TLR41	235
RAB31 marks and controls an ESCRT-independent exosome pathway	231
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages	225
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma	209
Metabolic signaling in T cells	200
Calreticulin and cancer	196
Coinfection with influenza A virus enhances SARS-CoV-2 infectivity	174
Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques	169
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8	168
SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination	151
Molecular subtyping and genomic profiling expand precision medicine in refractory metastatic triple-negative breast cancer: the FUTURE trial	143
Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA	131
A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2	124
Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines	124
Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma	119
A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice	117
The basis of a more contagious 501Y.V1 variant of SARS-CoV-2	116
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome	112
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2	107
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing	105
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	103

The m6A methylome of SARS-CoV-2 in host cells	100
A cohort autopsy study defines COVID-19 systemic pathogenesis	98
Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain	95
Degradation of lipid droplets by chimeric autophagy-tethering compounds	95
Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates	94
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19	94
Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients	94
25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor	90
Single-cell transcriptomic atlas of primate cardiopulmonary aging	86
Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2	85
The SARS-CoV-2 spike protein: balancing stability and infectivity	84
Molecular basis for ligand activation of the human KCNQ2 channel	83
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models	82
Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms	81
Structural basis for nucleosome-mediated inhibition of cGAS activity	79
A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid–liquid phase separation to promote oncogenic YAP signaling	78
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2	77
Enhancing prime editing by Csy4-mediated processing of pegRNA	76
SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs	76
Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern	75
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells	74
Neddylation of PTEN regulates its nuclear import and promotes tumor development	73
Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection	73
Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection	73
Structure-based development of human antibody cocktails against SARS-CoV-2	72
Resolving individual atoms of protein complex by cryo-electron microscopy	72
O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an “O-Follow-N” rule	71
Wnt signaling and Loxl2 promote aggressive osteosarcoma	71
Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR	69
Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine	68
SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation	68
Genome-scale profiling of circulating cell-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients	67
Dysregulated adaptive immune response contributes to severe COVID-19	67
A novel somatosensory spatial navigation system outside the hippocampal formation	66
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling	65
Predicting dynamic cellular protein–RNA interactions by deep learning using in vivo RNA structures	65
Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level	65
An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments	63
Pulmonary alveolar regeneration in adult COVID-19 patients	63
Lateral transfer of mRNA and protein by migrasomes modifies the recipient cells	63
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration	62
A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs	62