Cell Research

(The TQCC of Cell Research is 62. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Interaction between microbiota and immunity in health and disease1701
Ferroptosis: molecular mechanisms and health implications1394
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease635
Immune checkpoint signaling and cancer immunotherapy590
The future of cancer immunotherapy: microenvironment-targeting combinations453
A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling366
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy352
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells343
COVID-19: towards understanding of pathogenesis252
SARS-CoV-2 infects human neural progenitor cells and brain organoids250
SARS-CoV-2 spike protein interacts with and activates TLR41216
RAB31 marks and controls an ESCRT-independent exosome pathway209
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages209
Metabolic signaling in T cells185
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma182
Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice181
Calreticulin and cancer176
Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques166
Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient165
Coinfection with influenza A virus enhances SARS-CoV-2 infectivity159
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals159
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions146
SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination144
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8142
Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases141
863 genomes reveal the origin and domestication of chicken137
Molecular subtyping and genomic profiling expand precision medicine in refractory metastatic triple-negative breast cancer: the FUTURE trial133
Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma124
Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA123
A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2121
Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines119
A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice111
Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity111
The basis of a more contagious 501Y.V1 variant of SARS-CoV-2110
Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma106
Old dogs, new trick: classic cancer therapies activate cGAS103
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome99
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target96
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-295
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing94
The m6A methylome of SARS-CoV-2 in host cells94
Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients93
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer90
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-1989
Reconstruction of cell spatial organization from single-cell RNA sequencing data based on ligand-receptor mediated self-assembly88
Degradation of lipid droplets by chimeric autophagy-tethering compounds88
A cohort autopsy study defines COVID-19 systemic pathogenesis88
Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates86
25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor86
Single-cell transcriptomic atlas of primate cardiopulmonary aging81
Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain81
The SARS-CoV-2 spike protein: balancing stability and infectivity80
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models79
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration79
Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE277
Molecular basis for ligand activation of the human KCNQ2 channel76
High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing75
Cryo-EM structures of inactive and active GABAB receptor74
Structural basis for nucleosome-mediated inhibition of cGAS activity73
Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms73
Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection72
Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern72
Structure-based development of human antibody cocktails against SARS-CoV-272
Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection71
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-271
A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid–liquid phase separation to promote oncogenic YAP signaling70
Enhancing prime editing by Csy4-mediated processing of pegRNA70
Resolving individual atoms of protein complex by cryo-electron microscopy68
Wnt signaling and Loxl2 promote aggressive osteosarcoma66
Dysregulated adaptive immune response contributes to severe COVID-1966
O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an “O-Follow-N” rule66
SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs66
Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine65
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells65
Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR62
Neddylation of PTEN regulates its nuclear import and promotes tumor development62
SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation62
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration62
Pulmonary alveolar regeneration in adult COVID-19 patients62
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling62