OOIR: Observatory of International Research

Papers

(The TQCC of Cell Research is 60. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Ferroptosis: molecular mechanisms and health implications	1891
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells	374
SARS-CoV-2 spike protein interacts with and activates TLR41	252
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages	234
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8	183
Coinfection with influenza A virus enhances SARS-CoV-2 infectivity	181
SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination	156
Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines	128
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome	126
The basis of a more contagious 501Y.V1 variant of SARS-CoV-2	115
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	113
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2	112
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing	112
The m6A methylome of SARS-CoV-2 in host cells	105
A cohort autopsy study defines COVID-19 systemic pathogenesis	104
Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain	103
Degradation of lipid droplets by chimeric autophagy-tethering compounds	102
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19	101
Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates	95
Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2	90
The SARS-CoV-2 spike protein: balancing stability and infectivity	87
A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid–liquid phase separation to promote oncogenic YAP signaling	85
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models	85
Enhancing prime editing by Csy4-mediated processing of pegRNA	83
Neddylation of PTEN regulates its nuclear import and promotes tumor development	82

Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms	81
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2	80
O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an “O-Follow-N” rule	78
Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern	76
Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection	75
A novel somatosensory spatial navigation system outside the hippocampal formation	74
Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection	74
Structure-based development of human antibody cocktails against SARS-CoV-2	73
Resolving individual atoms of protein complex by cryo-electron microscopy	73
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling	73
Genome-scale profiling of circulating cell-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients	71
Predicting dynamic cellular protein–RNA interactions by deep learning using in vivo RNA structures	70
SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation	70
Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration	69
Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine	69
In vivo self-assembled small RNAs as a new generation of RNAi therapeutics	67
Formative pluripotent stem cells show features of epiblast cells poised for gastrulation	65
A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs	65
An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments	64
Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics	64
Mechanisms of Polycomb group protein function in cancer	63
Time of day influences immune response to an inactivated vaccine against SARS-CoV-2	63
Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor	61
Structural basis of human α7 nicotinic acetylcholine receptor activation	60
Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2	60