OOIR: Observatory of International Research

Papers

(The median citation count of Cell Research is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Ferroptosis: molecular mechanisms and health implications	1891
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells	374
SARS-CoV-2 spike protein interacts with and activates TLR41	252
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages	234
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8	183
Coinfection with influenza A virus enhances SARS-CoV-2 infectivity	181
SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination	156
Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines	128
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome	126
The basis of a more contagious 501Y.V1 variant of SARS-CoV-2	115
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	113
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing	112
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2	112
The m6A methylome of SARS-CoV-2 in host cells	105
A cohort autopsy study defines COVID-19 systemic pathogenesis	104
Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain	103
Degradation of lipid droplets by chimeric autophagy-tethering compounds	102
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19	101
Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates	95
Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2	90
The SARS-CoV-2 spike protein: balancing stability and infectivity	87
A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid–liquid phase separation to promote oncogenic YAP signaling	85
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models	85
Enhancing prime editing by Csy4-mediated processing of pegRNA	83
Neddylation of PTEN regulates its nuclear import and promotes tumor development	82

Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms	81
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2	80
O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an “O-Follow-N” rule	78
Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern	76
Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection	75
A novel somatosensory spatial navigation system outside the hippocampal formation	74
Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection	74
Structure-based development of human antibody cocktails against SARS-CoV-2	73
Resolving individual atoms of protein complex by cryo-electron microscopy	73
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling	73
Genome-scale profiling of circulating cell-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients	71
Predicting dynamic cellular protein–RNA interactions by deep learning using in vivo RNA structures	70
SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation	70
Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration	69
Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine	69
In vivo self-assembled small RNAs as a new generation of RNAi therapeutics	67
Formative pluripotent stem cells show features of epiblast cells poised for gastrulation	65
A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs	65
Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics	64
An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments	64
Time of day influences immune response to an inactivated vaccine against SARS-CoV-2	63
Mechanisms of Polycomb group protein function in cancer	63
Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor	61
Structural basis of human α7 nicotinic acetylcholine receptor activation	60
Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2	60
Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition	59
Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses	58
Generation and characterization of stable pig pregastrulation epiblast stem cell lines	57
RNA m6A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability	55
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan	54
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor	54
Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies	54
Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2	52
Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma	51
Structures of active melanocortin-4 receptor–Gs-protein complexes with NDP-α-MSH and setmelanotide	44
Tumor-conditional IL-15 pro-cytokine reactivates anti-tumor immunity with limited toxicity	44
Molecular basis of ligand recognition and activation of human V2 vasopressin receptor	44
Gephyrin-mediated formation of inhibitory postsynaptic density sheet via phase separation	43
Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation	43
CaMKIIα-driven, phosphatase-checked postsynaptic plasticity via phase separation	43
Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals	43
Merging PROTAC and molecular glue for degrading BTK and GSPT1 proteins concurrently	42
Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor	40
A distinct D1-MSN subpopulation down-regulates dopamine to promote negative emotional state	40
Publisher Correction: SARS-CoV-2 spike protein interacts with and activates TLR4	39
A new type of ERGIC–ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis	39
Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1	38
Structural insights into the membrane microdomain organization by SPFH family proteins	36
Rapid development of an updated mRNA vaccine against the SARS-CoV-2 Omicron variant	36
Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant	35

Cryo-EM structures of the full-length human KCC2 and KCC3 cation-chloride cotransporters	35
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury	35
Structural insights into ligand recognition and activation of the melanocortin-4 receptor	34
Mutual dependency between lncRNA LETN and protein NPM1 in controlling the nucleolar structure and functions sustaining cell proliferation	34
Mechanical activation of spike fosters SARS-CoV-2 viral infection	33
Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells	33
Lipid nanoparticle-encapsulated mRNA antibody provides long-term protection against SARS-CoV-2 in mice and hamsters	32
Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis	32
Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants	32
Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2	32
Mispair-bound human MutS–MutL complex triggers DNA incisions and activates mismatch repair	31
Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3–Gi signaling complexes	31
Ferroptosis: the Good, the Bad and the Ugly	30
Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans	30
The ChinaMAP reference panel for the accurate genotype imputation in Chinese populations	29
Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1	29
Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs	29
EGFR signaling promotes nuclear translocation of plasma membrane protein TSPAN8 to enhance tumor progression via STAT3-mediated transcription	28
Tracing the origins of SARS-CoV-2: lessons learned from the past	28
Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study	28
Zipper head mechanism of telomere synthesis by human telomerase	27
Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms	26
Cryo-EM structure of the AVP–vasopressin receptor 2–Gs signaling complex	25
Structure of human RNA polymerase III elongation complex	24
Pharmacological inhibition of SRC-1 phase separation suppresses YAP oncogenic transcription activity	24