OOIR: Observatory of International Research

Papers

(The median citation count of Cell Research is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
ERASE: a novel nucleic-acid based antiviral mechanism	268
A cohort autopsy study defines COVID-19 systemic pathogenesis	200
Finding a new job: glutamate signaling acts in atrial cardiomyocytes	198
Novel attempts launched toward universal Sarbecovirus vaccine	156
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development	128
RNA m6A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability	126
Muscularis macrophages: trained guardians of enteric neurons	117
Developments in pluripotency: a new formative state	115
TMED9–SEC12, an important “contact” for autophagy	107
Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells	104
A new molecular target for antidepressants	103
A distinct D1-MSN subpopulation down-regulates dopamine to promote negative emotional state	95
An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments	91
EGFR signaling promotes nuclear translocation of plasma membrane protein TSPAN8 to enhance tumor progression via STAT3-mediated transcription	90
Tracing the origins of SARS-CoV-2: lessons learned from the past	89
The basis of a more contagious 501Y.V1 variant of SARS-CoV-2	84
SARS-CoV-2 spike protein interacts with and activates TLR41	83
Time of day influences immune response to an inactivated vaccine against SARS-CoV-2	83
Double insult: flu bug enhances SARS-CoV-2 infectivity	77
Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2	76
Regulators of tubulin polyglutamylation control nuclear shape and cilium disassembly by balancing microtubule and actin assembly	73
Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans	71
O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an “O-Follow-N” rule	70
Tumor-conditional IL-15 pro-cytokine reactivates anti-tumor immunity with limited toxicity	70
Enhancing prime editing by Csy4-mediated processing of pegRNA	69

Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor	69
Publisher Correction: SARS-CoV-2 spike protein interacts with and activates TLR4	67
Author Correction: Mechanical activation of spike fosters SARS-CoV-2 infection	67
Author Correction: Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma	67
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2	65
Publisher Correction: Gephyrin: a scaffold that builds a phase at the inhibitory postsynapses	65
Remote light-activation of native Orai channels	63
Intestinal tête-à-tête: helminths blunt immunity against flaviviruses	61
A spatial map out of place	60
To learn something new, do something new	60
Timing vaccination against SARS-CoV-2	59
Structure-based analyses of neutralization antibodies interacting with naturally occurring SARS-CoV-2 RBD variants	56
Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function	55
Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms	54
Beyond targeted protein degradation: LD·ATTECs clear cellular lipid droplets	52
It’s just a phase: NLRP6 phase separations drive signaling	52
SARS-CoV-2 vaccines: anamnestic response in previously infected recipients	48
Heart defects recapitulated in human cardioids	48
Structural basis of human α7 nicotinic acetylcholine receptor activation	43
An exercise infusion benefits brain function	43
Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F–G protein complex	42
Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139	40
Humoral immunogenicity and reactogenicity of CoronaVac or ZF2001 booster after two doses of inactivated vaccine	40
A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs	40
Remembering past infections: training exercise for gut microbes	40
Vein to artery: the first arteriogenesis in the mammalian embryo	40
3D genome encoded by LINE and SINE repeats	39
Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates	36
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8	36
Coinfection with influenza A virus enhances SARS-CoV-2 infectivity	35
Cholesterylation of Smoothened is a calcium-accelerated autoreaction involving an intramolecular ester intermediate	34
Cryo-EM structure of the AVP–vasopressin receptor 2–Gs signaling complex	33
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells	33
The hens guarding epithelial cancer fox-houses	32
Author Corrections: VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex	32
Author Correction: The mitochondrial genome encodes abundant small noncoding RNAs	32
Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain	32
Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals	31
Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis	30
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling	29
Pancreatic endocrinogenesis revisited: “I have all the answers, who has the questions?”	29
Self-made allostery: endogenous COMP antagonizes pathologic AT1AR signaling	29
How did a novel X-linked gene become essential for male determination?	28
Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor	28
UHRF1: a novel metabolic guardian restricting AMPK activity	27
Structural basis of acyl-CoA transport across the peroxisomal membrane by human ABCD1	27
TDP-43 triggers immune response via mitochondrial DNA release	26
Panning for brain antigens in dural sinuses	24
Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics	24
SPFH protein cage — one ring to rule them all	23

Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant	23
Identification of an endogenous glutamatergic transmitter system controlling excitability and conductivity of atrial cardiomyocytes	21
Somatic mutation accumulation seen through a single-molecule lens	20
Cryo-EM structure of the nuclear ring from Xenopus laevis nuclear pore complex	20
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan	20
Author Correction: Threshold for neural tube defect risk by accumulated singleton loss-of-function variants	20
Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study	20