OOIR: Observatory of International Research

Papers

(The H4-Index of Neurobiology of Disease is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier	336
Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis	116
How specific are the conformation-specific α-synuclein antibodies? Characterization and validation of 16 α-synuclein conformation-specific antibodies using well-characterized preparations of α-synucle	107
Long-lasting blood-brain barrier dysfunction and neuroinflammation after traumatic brain injury	106
Neuropathological evidence of body-first vs. brain-first Lewy body disease	102
Microglia reprogram metabolic profiles for phenotype and function changes in central nervous system	99
Plasmalogens, platelet-activating factor and beyond – Ether lipids in signaling and neurodegeneration	82
Exosome-mediated delivery of antisense oligonucleotides targeting α-synuclein ameliorates the pathology in a mouse model of Parkinson's disease	81
Oligomeric α-Syn and SNARE complex proteins in peripheral extracellular vesicles of neural origin are biomarkers for Parkinson's disease	74
INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia	73
Clinical and imaging evidence of brain-first and body-first Parkinson's disease	69
Obstructive Sleep Apnea and Its Treatment in Aging: Effects on Alzheimer’s disease Biomarkers, Cognition, Brain Structure and Neurophysiology	68
Local field potentials in Parkinson's disease: A frequency-based review	67
Chronic stress induces formation of stress granules and pathological TDP-43 aggregates in human ALS fibroblasts and iPSC-motoneurons	65
Co-expression patterns of microglia markers Iba1, TMEM119 and P2RY12 in Alzheimer's disease	64
Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response	63
Cilia, ciliopathies and hedgehog-related forebrain developmental disorders	62
An integrated metagenomics and metabolomics approach implicates the microbiota-gut-brain axis in the pathogenesis of Huntington's disease	62
Primary cilia and ciliary signaling pathways in aging and age-related brain disorders	60
Schwann cell functions in peripheral nerve development and repair	60
Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease	60
Soluble TREM2: Innocent bystander or active player in neurological diseases?	59
TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia	58
The genetic architecture of ALS	57
Primary motor cortex in Parkinson’s disease: Functional changes and opportunities for neurostimulation	57

Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease	55
Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation	55
Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration	55
Mechanosensation in traumatic brain injury	52
SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein	51
Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders	50
Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease	50
Animal models of brain-first and body-first Parkinson's disease	46
Small RNA modifications in Alzheimer's disease	45
The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes	45
PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats	45
Molecular chaperones and Parkinson's disease	45
Plasma neurofilament light chain predicts cerebellar atrophy and clinical progression in spinocerebellar ataxia	45
What are activated and reactive glia and what is their role in neurodegeneration?	44
Neuron-astrocyte transmitophagy is altered in Alzheimer's disease	42
Brain edema formation and therapy after intracerebral hemorrhage	41
Glucocerebrosidase-associated Parkinson disease: Pathogenic mechanisms and potential drug treatments	41