OOIR: Observatory of International Research

Papers

(The H4-Index of Gene Therapy is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
First use of gene therapy to treat growth hormone resistant dwarfism in a mouse model	102
Serotype-specific transduction of canine joint tissue explants and cultured monolayers by self-complementary adeno-associated viral vectors	68
A shedding analysis after AAV8 CNS injection revealed fragmented viral DNA without evidence of functional AAV particles in mice	54
Overexpressed ski efficiently promotes neurorestoration, increases neuronal regeneration, and reduces astrogliosis after traumatic brain injury	50
Review of cardiac safety in onasemnogene abeparvovec gene replacement therapy: translation from preclinical to clinical findings	39
AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumonia	39
Preclinical evaluation of FLT190, a liver-directed AAV gene therapy for Fabry disease	37
Highly efficient and specific regulation of gene expression using enhanced CRISPR-Cas12f system	35
Gene therapy for spinal muscular atrophy: the Qatari experience	33
Clinical enrollment assay to detect preexisting neutralizing antibodies to AAV6 with demonstrated transgene expression in gene therapy trials	33
Rapid characterization of adeno-associated virus (AAV) gene therapy vectors by mass photometry	31
Control of gene doping in human and horse sports	30
Correction: The disparate burden of infectious diseases	28
Gene therapy restores mitochondrial function and protects retinal ganglion cells in optic neuropathy induced by a mito-targeted mutant ND1 gene	28
The AAV2.7m8 capsid packages a higher degree of heterogeneous vector genomes than AAV2	26
Viral vector gene delivery of the novel chaperone protein SRCP1 to modify insoluble protein in in vitro and in vivo models of ALS	25
Correction: Nr2e3 is a genetic modifier that rescues retinal degeneration and promotes homeostasis in multiple models of retinitis pigmentosa	24
Implications of maternal-fetal health on perinatal stem cell banking	24
Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxis	22
Correction: Site-specific modifications to AAV8 capsid yields enhanced brain transduction in the neonatal MPS IIIB mouse	22
Unlocking patient access to gene therapy: five key practices	22
Ultra-sensitive AAV capsid detection by immunocapture-based qPCR following factor VIII gene transfer	22