OOIR: Observatory of International Research

Papers

(The TQCC of Angiogenesis is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity	305
Senescent endothelial cells: a potential target for diabetic retinopathy	92
Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization	83
People with a connective tissue disorder may be especially vulnerable to the endothelial damage that characterizes long COVID due to the fragility of their vasculature and slow wound healing	79
The role of vasculature and angiogenesis in respiratory diseases	77
Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression	67
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations	57
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy	45
The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions	42
Soluble FLT-1 in angiogenesis: pathophysiological roles and therapeutic implications	40
Alk1/Endoglin signaling restricts vein cell size increases in response to hemodynamic cues	39
BMP10 functions independently from BMP9 for the development of a proper arteriovenous network	38
Coalescent angiogenesis—evidence for a novel concept of vascular network maturation	34
PDGFD switches on stem cell endothelial commitment	33
FGF21 via mitochondrial lipid oxidation promotes physiological vascularization in a mouse model of Phase I ROP	32
Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis	30
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation	28
Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors	26
Nectins and Nectin-like molecules drive vascular development and barrier function	26
In vivo dissection of Rhoa function in vascular development using zebrafish	25
Multimodality imaging reveals angiogenic evolution in vivo during calvarial bone defect healing	23
Correction: Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats	23
Diminished vasculogenesis under inflammatory conditions is mediated by Activin A	22
Persistent capillary rarefication in long COVID syndrome	20
CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation	19

On coalescent angiogenesis and the remarkable flexibility of blood vessels	19
Vascular mimicry in zebrafish fin regeneration: how macrophages build new blood vessels	19
Localized conditional induction of brain arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia	18
KIT is dispensable for physiological organ vascularisation in the embryo	18
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations	17
The rising impact of angiogenesis research	17
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis	16
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial	16
Role of endothelial PDGFB in arterio-venous malformations pathogenesis	16
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE−/− mice	15
MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia	15
Reply to “Embracing imatinib: a novel approach to safeguarding the endothelial barrier in patients with COVID-19”	15
Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice	15
Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss	15