OOIR: Observatory of International Research

Papers

(The TQCC of Angiogenesis is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity	318
Senescent endothelial cells: a potential target for diabetic retinopathy	96
Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization	90
Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression	86
The role of vasculature and angiogenesis in respiratory diseases	81
People with a connective tissue disorder may be especially vulnerable to the endothelial damage that characterizes long COVID due to the fragility of their vasculature and slow wound healing	68
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations	59
Soluble FLT-1 in angiogenesis: pathophysiological roles and therapeutic implications	47
The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions	45
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy	45
PDGFD switches on stem cell endothelial commitment	43
Alk1/Endoglin signaling restricts vein cell size increases in response to hemodynamic cues	40
Coalescent angiogenesis—evidence for a novel concept of vascular network maturation	37
BMP10 functions independently from BMP9 for the development of a proper arteriovenous network	36
Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors	35
Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis	33
In vivo dissection of Rhoa function in vascular development using zebrafish	29
FGF21 via mitochondrial lipid oxidation promotes physiological vascularization in a mouse model of Phase I ROP	29
Nectins and Nectin-like molecules drive vascular development and barrier function	29
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation	25
Multimodality imaging reveals angiogenic evolution in vivo during calvarial bone defect healing	25
Correction: Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats	24
Persistent capillary rarefication in long COVID syndrome	23
Diminished vasculogenesis under inflammatory conditions is mediated by Activin A	20
Vascular mimicry in zebrafish fin regeneration: how macrophages build new blood vessels	20

KIT is dispensable for physiological organ vascularisation in the embryo	19
The rising impact of angiogenesis research	19
On coalescent angiogenesis and the remarkable flexibility of blood vessels	19
CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation	19
Role of endothelial PDGFB in arterio-venous malformations pathogenesis	17
Localized conditional induction of brain arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia	17
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis	17
MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia	17
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial	16
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations	16
Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss	16
Reply to “Embracing imatinib: a novel approach to safeguarding the endothelial barrier in patients with COVID-19”	16