OOIR: Observatory of International Research

Papers

(The median citation count of Angiogenesis is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects	121
Pathological angiogenesis: mechanisms and therapeutic strategies	113
Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality	100
High endothelial venules (HEVs) in immunity, inflammation and cancer	86
Vascular endothelial cell specification in health and disease	60
Endothelial cell plasticity at the single-cell level	57
Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance	56
Angiodiversity and organotypic functions of sinusoidal endothelial cells	55
Angiogenesis in adipose tissue and obesity	51
First blood: the endothelial origins of hematopoietic progenitors	50
In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed	49
Role of Notch in endothelial biology	45
Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity	43
Persistent capillary rarefication in long COVID syndrome	41
Pericyte hypoxia-inducible factor-1 (HIF-1) drives blood-brain barrier disruption and impacts acute ischemic stroke outcome	41
Extracellular matrix stiffness controls VEGF165 secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis	33
Mechanisms and cell lineages in lymphatic vascular development	33
TAK1 signaling is a potential therapeutic target for pathological angiogenesis	30
The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis	29
A novel lymphatic pattern promotes metastasis of cervical cancer in a hypoxic tumour-associated macrophage-dependent manner	28
Hydrogel-mediated delivery of microRNA-92a inhibitor polyplex nanoparticles induces localized angiogenesis	28
Characterization of the heterogeneity of endothelial cells in bleomycin-induced lung fibrosis using single-cell RNA sequencing	27
YAP promotes ocular neovascularization by modifying PFKFB3-driven endothelial glycolysis	27
Von Willebrand factor collagen-binding capacity predicts in-hospital mortality in COVID-19 patients: insight from VWF/ADAMTS13 ratio imbalance	26
Coalescent angiogenesis—evidence for a novel concept of vascular network maturation	26

Chemerin regulates normal angiogenesis and hypoxia-driven neovascularization	25
SMAD6 transduces endothelial cell flow responses required for blood vessel homeostasis	25
Pazopanib for severe bleeding and transfusion-dependent anemia in hereditary hemorrhagic telangiectasia	25
Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2	23
The vascularization paradox of non-union formation	23
The DOCK protein family in vascular development and disease	22
Resident vascular endothelial progenitor definition and function: the age of reckoning	22
Damage to endothelial barriers and its contribution to long COVID	21
To be or not to be: endothelial cell plasticity in development, repair, and disease	20
Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway	19
Inflammation and vascular remodeling in COVID-19 hearts	19
Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation	18
Circulating level of Angiopoietin-2 is associated with acute kidney injury in coronavirus disease 2019 (COVID-19)	18
Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression	17
Endothelium-specific deletion of Nox4 delays retinal vascular development and mitigates pathological angiogenesis	17
Linalool inhibits the angiogenic activity of endothelial cells by downregulating intracellular ATP levels and activating TRPM8	17
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation	16
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy	16
Angiogenesis: a year in review	16
Peritumoral B cells drive proangiogenic responses in HMGB1-enriched esophageal squamous cell carcinoma	16
Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis	16
PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting	15
A novel somatic mutation in GNAQ in a capillary malformation provides insight into molecular pathogenesis	15
Effect of erythrophagocytosis-induced ferroptosis during angiogenesis in atherosclerotic plaques	15
TFEB controls integrin-mediated endothelial cell adhesion by the regulation of cholesterol metabolism	14
CCM2-deficient endothelial cells undergo a ROCK-dependent reprogramming into senescence-associated secretory phenotype	14
Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking	14
The rising impact of angiogenesis research	14
7-ketocholesterol induces endothelial-mesenchymal transition and promotes fibrosis: implications in neovascular age-related macular degeneration and treatment	14
PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis	14
Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization	14
Oral itraconazole for epistaxis in hereditary hemorrhagic telangiectasia: a proof of concept study	12
NRASQ61R mutation in human endothelial cells causes vascular malformations	12
Therapeutic angiogenesis for patients with no-option critical limb ischemia by adipose-derived regenerative cells: TACT-ADRC multicenter trial	12
Unique functions for Notch4 in murine embryonic lymphangiogenesis	12
Trafficking in blood vessel development	11
MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia	11
The HGR motif is the antiangiogenic determinant of vasoinhibin: implications for a therapeutic orally active oligopeptide	11
Identification of vascular cues contributing to cancer cell stemness and function	11
Targeting SMYD2 inhibits angiogenesis and increases the efficiency of apatinib by suppressing EGFL7 in colorectal cancer	11
Plasma levels of angiopoietin-2, VEGF-A, and VCAM-1 as markers of bevacizumab-induced hypertension: CALGB 80303 and 90401 (Alliance)	10
Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression	10
Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis: the MICROCODE study	10
Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis	10
Modeling angiogenesis in the human brain in a tissue-engineered post-capillary venule	10
The modes of angiogenesis: an updated perspective	9
Human endothelial colony-forming cells provide trophic support for pluripotent stem cell-derived cardiomyocytes via distinctively high expression of neuregulin-1	9
The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions	9
BMP10 functions independently from BMP9 for the development of a proper arteriovenous network	9
Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling	9

The role of redox system in metastasis formation	8
Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice	8
KIT is dispensable for physiological organ vascularisation in the embryo	8
Nectins and Nectin-like molecules drive vascular development and barrier function	8
The adaptor protein Grb2b is an essential modulator for lympho-venous sprout formation in the zebrafish trunk	8
RIPK3 modulates growth factor receptor expression in endothelial cells to support angiogenesis	8
S100A4-dependent glycolysis promotes lymphatic vessel sprouting in tumor	8
Protein disulfide isomerase A1 as a novel redox sensor in VEGFR2 signaling and angiogenesis	8
VEGF-A plasma levels are associated with impaired DLCO and radiological sequelae in long COVID patients	7
Endothelial hyperactivation of mutant MAP3K3 induces cerebral cavernous malformation enhanced by PIK3CA GOF mutation	7
In vivo dissection of Rhoa function in vascular development using zebrafish	7
Refractory severe idiopathic systemic capillary leak syndrome successfully treated with bevacizumab: a case report	7
Somatic GJA4 gain-of-function mutation in orbital cavernous venous malformations	7
Tissue oxygenation stabilizes neovessels and mitigates hemorrhages in human atherosclerosis-induced angiogenesis	7
FGF21 via mitochondrial lipid oxidation promotes physiological vascularization in a mouse model of Phase I ROP	6
Letter in response to: circulating von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality	5
Localized conditional induction of brain arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia	5
Phenotypic screening in Organ-on-a-Chip systems: a 1537 kinase inhibitor library screen on a 3D angiogenesis assay	5
Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription	5
Extracellular matrix stiffness controls VEGF165 secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis	5
Plasma ratio of angiopoietin-2 to angiopoietin-1 is a biomarker of vascular impairment in chronic obstructive pulmonary disease patients	5
Design and preclinical evaluation of a novel apelin-based PET radiotracer targeting APJ receptor for molecular imaging of angiogenesis	5
Deletion of endothelial α-parvin inhibits tumour angiogenesis, reduces tumour growth and induces tumour cell apoptosis	5
Role of TGFβ1 and WNT6 in FGF2 and BMP4-driven endothelial differentiation of murine embryonic stem cells	5
On coalescent angiogenesis and the remarkable flexibility of blood vessels	5