OOIR: Observatory of International Research

Papers

(The median citation count of Angiogenesis is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization	200
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity	138
Senescent endothelial cells: a potential target for diabetic retinopathy	114
Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling	75
Role of TGFβ1 and WNT6 in FGF2 and BMP4-driven endothelial differentiation of murine embryonic stem cells	70
Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression	69
People with a connective tissue disorder may be especially vulnerable to the endothelial damage that characterizes long COVID due to the fragility of their vasculature and slow wound healing	65
The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis	56
The role of vasculature and angiogenesis in respiratory diseases	54
The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions	51
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy	43
Soluble FLT-1 in angiogenesis: pathophysiological roles and therapeutic implications	38
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations	37
Letter in response to: circulating von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality	35
PDGFD switches on stem cell endothelial commitment	35
Alk1/Endoglin signaling restricts vein cell size increases in response to hemodynamic cues	33
Successful management of lung adenocarcinoma with ALK/EGFR co-alterations and PD-L1 over-expression by bevacizumab combined with chemotherapy	33
BMP10 functions independently from BMP9 for the development of a proper arteriovenous network	32
Coalescent angiogenesis—evidence for a novel concept of vascular network maturation	32
Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking	30
In vivo dissection of Rhoa function in vascular development using zebrafish	28
Nectins and Nectin-like molecules drive vascular development and barrier function	26
Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors	26
FGF21 via mitochondrial lipid oxidation promotes physiological vascularization in a mouse model of Phase I ROP	25
Multimodality imaging reveals angiogenic evolution in vivo during calvarial bone defect healing	24

Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis	24
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation	24
Endothelial cell plasticity at the single-cell level	22
Correction to: Phosphorylation of pericyte FAK‑Y861 affects tumour cell apoptosis and tumour blood vessel regression	21
Correction: Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats	21
Pazopanib for severe bleeding and transfusion-dependent anemia in hereditary hemorrhagic telangiectasia	20
Persistent capillary rarefication in long COVID syndrome	19
Diminished vasculogenesis under inflammatory conditions is mediated by Activin A	19
KIT is dispensable for physiological organ vascularisation in the embryo	18
Vascular mimicry in zebrafish fin regeneration: how macrophages build new blood vessels	18
On coalescent angiogenesis and the remarkable flexibility of blood vessels	18
Blood vessels sense dermal stiffness via a novel mechanotransducer, APJ	17
Correction to: Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking	17
The rising impact of angiogenesis research	16
Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss	16
Localized conditional induction of brain arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia	16
CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation	16
Extracellular matrix stiffness controls VEGF165 secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis	15
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis	14
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations	14
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial	14
Role of endothelial PDGFB in arterio-venous malformations pathogenesis	14
MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia	14
Correction to: Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation	14
Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice	13
Reply to “Embracing imatinib: a novel approach to safeguarding the endothelial barrier in patients with COVID-19”	13
FOXO1 promotes endothelial cell elongation and angiogenesis by up-regulating the phosphorylation of myosin light chain 2	12
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE−/− mice	12
The influences of ApoE isoforms on endothelial adherens junctions and actin cytoskeleton responding to mCRP	12
Deletion of endothelial α-parvin inhibits tumour angiogenesis, reduces tumour growth and induces tumour cell apoptosis	12
S100A4-dependent glycolysis promotes lymphatic vessel sprouting in tumor	12
Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2L914F mutation in endothelial cells	12
Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties	11
Correction to: The role of redox system in metastasis formation	11
Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) drives abnormal pericyte-rich vasculature in triple-negative breast cancer	11
Microglia in retinal angiogenesis and diabetic retinopathy	11
Lactate secreted by glycolytic conjunctival melanoma cells attracts and polarizes macrophages to drive angiogenesis in zebrafish xenografts	10
Opposite response of lung adenocarcinoma and its choroidal metastases upon ramucirumab plus docetaxel therapy after immunotherapy: a case report	10
Refractory systemic capillary leak syndrome treated with bevacizumab: a case report	10
Systemic glucocorticoids link to long-term microvascular injury in COVID-19	10
Plasma ratio of angiopoietin-2 to angiopoietin-1 is a biomarker of vascular impairment in chronic obstructive pulmonary disease patients	9
Correction: The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells	9
Von Willebrand factor multimers during non-invasive ultrasound therapy for aortic valve stenosis	9
Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance	9
Correction to: BI1 is associated with microvascular protection in cardiac ischemia reperfusion injury via repressing Syk-Nox2-Drp1-mitochondrial fission pathways	9
Pathological angiogenesis: mechanisms and therapeutic strategies	9
The dynamics of the endothelial glycocalyx: a rare snapshot by electron microscopy	8
Angiogenesis: a year in review	7
Correction: Nectins and Nectin-like molecules drive vascular development and barrier function	7
IC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice	7

Inflammation and vascular remodeling in COVID-19 hearts	7
A novel quantitative angiogenesis assay based on visualized vascular organoid	7
The modes of angiogenesis: an updated perspective	7
Timed topical dexamethasone eye drops improve mitochondrial function to prevent severe retinopathy of prematurity	7
Evidence of premature vascular dysfunction in young adults who regularly use e-cigarettes and the impact of usage length	7
Endothelial heterogeneity and plasticity	6
Study on mitogenic activity of serum from patients with total coronary occlusions: relation to duration of occlusion	6
Somatic GJA4 gain-of-function mutation in orbital cavernous venous malformations	6
Somatic RIT1 delins in arteriovenous malformations hyperactivate RAS-MAPK signaling amenable to MEK inhibition	6
Design and preclinical evaluation of a novel apelin-based PET radiotracer targeting APJ receptor for molecular imaging of angiogenesis	6
Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2	6
Protein disulfide isomerase A1 as a novel redox sensor in VEGFR2 signaling and angiogenesis	5
The vascularization paradox of non-union formation	5
Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis: the MICROCODE study	5
Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype	5
Botulinum neurotoxin serotype A inhibited ocular angiogenesis through modulating glial activation via SOCS3	5
Circulating endothelial cells: a key biomarker of persistent fatigue after hospitalization for COVID-19	5
Phenotypic screening in Organ-on-a-Chip systems: a 1537 kinase inhibitor library screen on a 3D angiogenesis assay	5
Damage to endothelial barriers and its contribution to long COVID	5