OOIR: Observatory of International Research

Papers

(The median citation count of Angiogenesis is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Microvascular dysfunction in COVID-19: the MYSTIC study	198
New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury	192
Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients	191
COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects	103
Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality	94
BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF	85
Tumor-derived exosomes promote angiogenesis via adenosine A2B receptor signaling	65
High endothelial venules (HEVs) in immunity, inflammation and cancer	61
RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway	54
Pathological angiogenesis: mechanisms and therapeutic strategies	47
Endothelial cell plasticity at the single-cell level	46
Angiodiversity and organotypic functions of sinusoidal endothelial cells	45
Vascular endothelial cell specification in health and disease	44
First blood: the endothelial origins of hematopoietic progenitors	43
Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance	41
Piwi-interacting RNAs (piRNAs) as potential biomarkers and therapeutic targets for cardiovascular diseases	41
Role of Notch in endothelial biology	35
Novel Murine Models of Cerebral Cavernous Malformations	34
Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity	33
Persistent capillary rarefication in long COVID syndrome	33
Hedgehog signaling promotes angiogenesis directly and indirectly in pancreatic cancer	33
Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation	32
Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis	31
Apatinib as targeted therapy for advanced bone and soft tissue sarcoma: a dilemma of reversing multidrug resistance while suffering drug resistance itself	30
In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed	30

Mechanisms and cell lineages in lymphatic vascular development	29
Pericyte hypoxia-inducible factor-1 (HIF-1) drives blood-brain barrier disruption and impacts acute ischemic stroke outcome	29
Arterial endoglin does not protect against arteriovenous malformations	27
Angiogenesis in adipose tissue and obesity	27
IQGAP1 causes choroidal neovascularization by sustaining VEGFR2-mediated Rac1 activation	26
Angiogenic responses in a 3D micro-engineered environment of primary endothelial cells and pericytes	25
Hydrogel-mediated delivery of microRNA-92a inhibitor polyplex nanoparticles induces localized angiogenesis	24
Lymphangiogenesis and accumulation of reparative macrophages contribute to liver repair after hepatic ischemia–reperfusion injury	24
YAP promotes ocular neovascularization by modifying PFKFB3-driven endothelial glycolysis	24
Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice	24
The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis	24
Talin-dependent integrin activation is required for endothelial proliferation and postnatal angiogenesis	23
Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2	23
Heterogeneity and chimerism of endothelial cells revealed by single-cell transcriptome in orthotopic liver tumors	23
A novel lymphatic pattern promotes metastasis of cervical cancer in a hypoxic tumour-associated macrophage-dependent manner	22
Von Willebrand factor collagen-binding capacity predicts in-hospital mortality in COVID-19 patients: insight from VWF/ADAMTS13 ratio imbalance	22
Characterization of a neutralizing anti-human galectin-1 monoclonal antibody with angioregulatory and immunomodulatory activities	22
Raftlin is recruited by neuropilin-1 to the activated VEGFR2 complex to control proangiogenic signaling	22
Extracellular matrix stiffness controls VEGF165 secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis	22
A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization	22
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells	21
Characterization of the heterogeneity of endothelial cells in bleomycin-induced lung fibrosis using single-cell RNA sequencing	21
Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions	21
SMAD6 transduces endothelial cell flow responses required for blood vessel homeostasis	20
Coalescent angiogenesis—evidence for a novel concept of vascular network maturation	20
Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity	19
Pazopanib for severe bleeding and transfusion-dependent anemia in hereditary hemorrhagic telangiectasia	18
Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells	18
To be or not to be: endothelial cell plasticity in development, repair, and disease	18
The DOCK protein family in vascular development and disease	18
Chemerin regulates normal angiogenesis and hypoxia-driven neovascularization	18
RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain	18
Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway	17
TAK1 signaling is a potential therapeutic target for pathological angiogenesis	17
B-cell non-Hodgkin lymphoma: importance of angiogenesis and antiangiogenic therapy	17
Endothelium-specific deletion of Nox4 delays retinal vascular development and mitigates pathological angiogenesis	16
Free fatty acid receptor 4 activation protects against choroidal neovascularization in mice	16
Endothelial deletion of ADAM10, a key regulator of Notch signaling, causes impaired decidualization and reduced fertility in female mice	15
The vascularization paradox of non-union formation	15
Peritumoral B cells drive proangiogenic responses in HMGB1-enriched esophageal squamous cell carcinoma	15
Embryonic circulating endothelial progenitor cells	15
Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation	15
Resident vascular endothelial progenitor definition and function: the age of reckoning	15
Circulating level of Angiopoietin-2 is associated with acute kidney injury in coronavirus disease 2019 (COVID-19)	14
Angiogenesis: a year in review	14
Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis	14
Linalool inhibits the angiogenic activity of endothelial cells by downregulating intracellular ATP levels and activating TRPM8	13
7-ketocholesterol induces endothelial-mesenchymal transition and promotes fibrosis: implications in neovascular age-related macular degeneration and treatment	13
Roxadustat (FG-4592) accelerates pulmonary growth, development, and function in a compensatory lung growth model	13
CCM2-deficient endothelial cells undergo a ROCK-dependent reprogramming into senescence-associated secretory phenotype	11

Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization	11
Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression	11
Angiostatic effects of ascorbic acid: current status and future perspectives	11
Inflammation and vascular remodeling in COVID-19 hearts	11
PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting	11
Oral itraconazole for epistaxis in hereditary hemorrhagic telangiectasia: a proof of concept study	11
Trafficking in blood vessel development	10
TFEB controls integrin-mediated endothelial cell adhesion by the regulation of cholesterol metabolism	10
Therapeutic angiogenesis for patients with no-option critical limb ischemia by adipose-derived regenerative cells: TACT-ADRC multicenter trial	10
Damage to endothelial barriers and its contribution to long COVID	10
Tubulin carboxypeptidase activity of vasohibin-1 inhibits angiogenesis by interfering with endocytosis and trafficking of pro-angiogenic factor receptors	10
Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking	9
MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia	9
The HGR motif is the antiangiogenic determinant of vasoinhibin: implications for a therapeutic orally active oligopeptide	9
Unique functions for Notch4 in murine embryonic lymphangiogenesis	9
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy	9
Human endothelial colony-forming cells provide trophic support for pluripotent stem cell-derived cardiomyocytes via distinctively high expression of neuregulin-1	9
Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression	8
Plasma levels of angiopoietin-2, VEGF-A, and VCAM-1 as markers of bevacizumab-induced hypertension: CALGB 80303 and 90401 (Alliance)	8
The rising impact of angiogenesis research	8
A novel somatic mutation in GNAQ in a capillary malformation provides insight into molecular pathogenesis	8
Leopold Auerbach’s achievements in the field of vascular system	8
Targeting SMYD2 inhibits angiogenesis and increases the efficiency of apatinib by suppressing EGFL7 in colorectal cancer	8
Identification of vascular cues contributing to cancer cell stemness and function	8
Modeling angiogenesis in the human brain in a tissue-engineered post-capillary venule	8
Are antiangiogenics a good ‘partner’ for immunotherapy in ovarian cancer?	8
PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis	8
Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis: the MICROCODE study	8
Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling	8