Bioorganic & Medicinal Chemistry

Article	Citations
Synthesis and antiproliferative activity of (−)-cleistenolide, (6S)-cleistenolide and 4-substituted cleistenolide analogues	93
Current Japanese pharmaceutical chemistry	85
Targeting prolidase. A survey of the literature data to depict a structure-activity relationship frame and to address future studies for drug development	82
Synthesis and medicinal chemistry of tetronamides: Promising agrochemicals and antitumoral compounds	67
Synthesis and biological evaluation of pyrazole-fused oleanolic acid derivatives as novel inhibitors of inflammatory and osteoclast differentiation	54
Graphical abstract TOC	52
Contents continued	49
Production and synthesis of a novel 191Pt-labeled platinum complex and evaluation of its biodistribution in healthy mice	48
Crescent-shaped meta-substituted benzene derivatives as a new class of non-nucleoside ribonuclease A inhibitors	43
Selective targeting of human TET1 by cyclic peptide inhibitors: Insights from biochemical profiling	40
Editorial Board	40
Targeting m6A binding protein YTHDFs for cancer therapy	39
RNA-templated chemical synthesis of proapoptotic L- and d-peptides	35
Discovery of trisubstituted meta-carboranes as T cell activators by regulating CD28 cytoplasmic region and SH2 domains of Grb2 and PI3K interactions	34
Design, synthesis, biological activity and molecular docking studies of triazolopyridine derivatives as ASK1 inhibitors	34
Decades old glitazones still find niche in drug discoveries as PPAR-γ agonists: medicinal chemistry perspective, structure-activity relationships and therapeutic implications	33
Development of delivery carriers for plasmid DNA by conjugation of a helical template to oligoarginine	33
Innovative synthesis and purification method of fluorescent and bifunctional substrates for self-labelling protein tags	33
Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation	32
Research progress of STAT3-based dual inhibitors for cancer therapy	31
Graphical abstract TOC	31
Natural product-derived antifungals against Candida albicans: Chemical diversity and mechanisms of action	30
Design, synthesis and evaluation the bioactivities of novel 1,3-dimethyl-6-amino-1H-indazole derivatives as anticancer agents	30
Multiple approaches to repurposing drugs for neuroblastoma	28
Janus dendritic ionizable lipids with fine designed headgroup and tails to improve mRNA delivery efficiency	28

Discovery of 3-hydroxymethyl-azetidine derivatives as potent polymerase theta inhibitors	28
Sulfadoxine derivatization through multicomponent reactions to obtain new antiplasmodial compounds	28
Assessing the rigidity of cubanes and bicyclo(1.1.1)pentanes as benzene bioisosteres	27
Current development and structure–activity relationship study of berberine derivatives	27
Sustainable electrochemical C(sp3) − H oxygenation using water as the oxygen source	27
Design, synthesis and antibacterial evaluation of oxazolidinone derivatives containing N-methylglycyl or quaternary ammonium salts	27
A pharmacophore-based approach to demonstrating the scope of alcohol dehydrogenases	27
Exploring novel A2AAR antagonists: Design, synthesis, and evaluation of 2,6,9-trisubstituted purine derivatives as promising antifibrotic agents	27
Synthesis, evaluation of anti-breast cancer activity in vitro of ICS II derivatives and summary of the structure-activity relationship	27
Combining CuAAC reaction enables sialylated Bi- and triantennary pseudo mannose N-glycans for investigating Siglec-7 interactions	26
Graphical abstract TOC	26
Pentacyclic triterpene-amino acid derivatives induced apoptosis and autophagy in tumor cells, affected the JNK and PI3K/AKT/mTOR pathway	26
Graphical abstract TOC	26
Peptide-based CE-SELEX enables convenient isolation of aptamers specifically recognizing CD20-expressing cells	25
Editorial Board	25
Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase	25
Contents continued	25
Editorial Board	25
More than forty years of nucleic acid structural science	25
Graphical abstract TOC	24
Graphical abstract TOC	24
Graphical abstract TOC	24
Design, synthesis and biological evaluation of novel indole derivatives as gut-selective NaPi2b inhibitors	23
Design, synthesis, and antiviral activity of 1-aryl-4-arylmethylpiperazine derivatives as Zika virus inhibitors with broad antiviral spectrum	23
Chemical similarities and differences among inhibitors of nitric oxide synthase, arginase and dimethylarginine dimethylaminohydrolase-1: Implications for the design of novel enzyme inhibitors modulati	23
Concise synthesis of piperarborenine B	23
Discovery of 6-substituted indole and tetrahydroquinoline derivatives as selective HDAC8 inhibitors	23
Discovery of tetracyclic 1,2,4-triazoline-fused dibenzo[b,f][1,4]oxazepine as a potent anti-colorectal cancer agent with good efficacy and low toxicity	23
Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and β-amyloid inhibitors for the treatment of Alzheimer’s disease	23
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d]pyrimidines as potent HPK1 kinase inhibitors	22
Synthesis and evaluation of novel 4-thiazolidinone-5-nitrofuran hybrids as promising antimicrobial agents	22
CRBN ligand expansion for hematopoietic prostaglandin D2 synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles	21
Design, synthesis and biological evaluation of arylpropylamine derivatives as potential multi-target antidepressants	21
1,3-Disubstituted-1,2,4-triazin-6-ones with potent activity against androgen receptor-dependent prostate cancer cells	21
Structure activity relationship and target prediction for ABX464 analogues in Caenorhabditis elegans	21
Development of novel quinoline-NO donor hybrids inducing human breast cancer cells apoptosis via inhibition of topoisomerase I	21
Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors	21
Design, synthesis, and analgesia evaluation of novel Transient Receptor Potential Vanilloid 1 (TRPV1) agonists modified from Cannabidiol (CBD)	21
Di-indenopyridines as topoisomerase II-selective anticancer agents: Design, synthesis, and structure–activity relationships	20
Biphenyl-based small molecule inhibitors: Novel cancer immunotherapeutic agents targeting PD-1/PD-L1 interaction	20
In Vivo Imaging of Tumor Hypoxia by Maintaining Green Fluorescence of 9-Aminoanthracene Under Hypoxic Conditions	20
Editorial Board	20
Editorial Board	20
Graphical abstract TOC	20
Introduction of a carboxylic acid group into pyrazolylpyridine derivatives increased selectivity for inhibition of the 20-HETE synthase CYP4A11/4F2	19
In vivo imaging of fluorescent albumin modified with pyruvylated-human-type complex oligosaccharide reveals sialylation-like biodistribution and kinetics	19
The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues	19
3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile: A fluorescent molecule that induces differentiation in PC12 cells	19
Graphical abstract TOC	19
Design, synthesis and biological evaluation of phosphoroxy quinazoline derivatives as potential EGFRT790M/C797S inhibitors	19

Structure-activity relationships of middle-size cyclic peptides, KRAS inhibitors derived from an mRNA display	18
Novel trifluoromethylquinoline derivatives as potent tubulin polymerization inhibitors with antitumor activity	18
(±)-Agrimonolide: Efficient synthesis and treatment of inflammatory bowel disease via JAK1/STAT3 pathway inhibition	18
Synthesis and biological evaluation of O4′-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents	18
Small phenolic inhibitors of PfATP6, a Plasmodium falciparum calcium ATPase, as prototype antimalarials	18
Synthesis and mammalian cell compatibility of light-released glycan precursors for controlled metabolic engineering	17
Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A2 and B2 bound to duplex 5′-TAGTT sites	17
The 2022 Monkeypox outbreak: How the medicinal chemistry could help us?	17
Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors	17
Design, synthesis and biological evaluation of EGFR kinase inhibitors that spans the orthosteric and allosteric sites	17
Structural optimization of naturally derived Ar-turmerone, as novel neuroinflammation suppressors effective in an Alzheimer mouse model	17
Versatile fluorescent homobifunctional crosslinkers: expedient synthesis and application to di-affibody constructs for specific HER2+ cancer cell recognition	17
Design and synthesis 1H-Pyrrolo[2,3-b]pyridine derivatives as FLT3 inhibitors for the treatment of Acute myeloid Leukemia	17
Discovery of SYD5115, a novel orally active small molecule TSH-R antagonist	17
A turn for the worse: Aβ β-hairpins in Alzheimer’s disease	17
Cytotoxicity of cinchona alkaloid organocatalysts against MES-SA and MES-SA/Dx5 multidrug-resistant uterine sarcoma cell lines	16
Hetero-aryl bromide precursor fluorine-18 radiosynthesis and preclinical evaluation of a novel positron emission tomography (PET) tracer [18F]GSK1482160	16
Design and identification of brain-penetrant, potent, and selective 1,3-oxazole-based cholesterol 24-hydroxylase (CH24H) inhibitors	16
A TNF-α blocking peptide that reduces NF-κB and MAPK activity for attenuating inflammation	16
Fatty acid binding protein 5 inhibitors as novel anticancer agents against metastatic castration-resistant prostate cancer	16
4-Arylidene curcumin derivatives in vitro inhibit α-Synuclein aggregation and disaggregate the preformed fibril	16
Ligand- and structure-based identification of novel CDK9 inhibitors for the potential treatment of leukemia	16
Discovery of the thieno[2,3-b][1,4]thiazin-2(3H)-one STING inhibitors	16
Expanding antimicrobial chemotypes: indole-based DNA gyrase inhibitors with potential dual mechanism against multidrug-resistant bacteria	16
Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for	16
Inhibition of cytochrome bd oxidase in Mycobacterium tuberculosis by benzothiazole amides	16
Graphical abstract TOC	15
ClpP-based MtPTAC technology enables targeted degradation of inner mitochondrial membrane proteins	15
Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy	15
Editorial Board	15
Discovery and optimization of orally bioavailable and potent plasma Kallikrein inhibitors bearing a quaternary carbon	15
Thiazolidinones and related analogues as efficient antitrypanosomal agents	15
Graphical abstract TOC	15
Dimeric 1-(1H-indol-3-yl) urea as potent STING inhibitor to alleviate cisplatin-induced acute kidney injury in mice	15
Graphical abstract TOC	14
Synthesis and bioactive study of tricyclic cyclopentaimidazopyridin-6-carboxylates grafting benzylpiperazyl groups as cytoprotectant agents	14
Contents continued	14
Synthetic studies on the extracellular domain of the T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) using Trt-K10 solubilizing tags	14
Discovery and structure-activity relationship of Morita-Baylis-Hillman adducts as larvicides against dengue mosquito vector, Aedes aegypti (Diptera: Culicidae)	14
FDA-approved small molecule kinase inhibitors for cancer treatment (2001–2015): Medical indication, structural optimization, and binding mode Part I	14
An insight into the mechanistic role of (-)-Ampelopsin F from Vatica chinensis L. in inducing insulin secretion in pancreatic beta cells	14
Chemical design of radioiodinated probes with a metabolizable linkage for target-selective imaging of systemic amyloidosis	14
Graphical Abstract TOC	14
Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study	14
Design, synthesis and in vitro validation of bivalent binders of SARS-CoV-2 spike protein: Obeticholic, betulinic and glycyrrhetinic acids as building blocks	14
Graphical abstract TOC	14
Generation of an RNA aptamer against LipL32 of Leptospira isolated by Tripartite-hybrid SELEX coupled with in-house Python-aided unbiased data sorting	14
Synthesis and biological evaluation of novel isobenzofuran-1(3H)-one derivatives as antidepressant agents	14
Discovery of polymethoxyphenyl-pyridines bearing amino side chains as tubulin colchicine-binding site inhibitors	14
Editorial Board	14
Influence of N-arylsulfonamido d-valine N-substituents on the selectivity and potency of matrix metalloproteinase inhibitors	14
Fluorescent probes and degraders of the sterol transport protein Aster-A	14
Phenotypic screen identifies FOXO inhibitor to counteract maturation and promote expansion of human iPS cell-derived cardiomyocytes	13
Drug discovery targeting nicotinamide phosphoribosyltransferase (NAMPT): Updated progress and perspectives	13
Synthesis, biological activity and mechanism of action of novel allosecurinine derivatives as potential antitumor agents	13
Design, synthesis and molecular modelling studies of bile acid-curcumin conjugates as potential antiproliferative agents for breast cancer	13
Exploring novel pyrazole-nitroimidazole hybrids: Synthesis and antiprotozoal activity against the human pathogen trichomonas vaginalis	13
Structure-activity relationship study of a new class of 2-amino-3,4-dihydroquinazolines as antitubercular agents	13
Growth factors and their peptide mimetics for treatment of traumatic brain injury	13
Synthesis and antibacterial properties under blue LED light of conjugates between the siderophore desferrioxamine B (DFOB) and an Iridium(III) complex	13
Generation of enantiospecific monoclonal antibodies against (2R,6R)-hydroxynorketamine	13
Fragment merging design, synthesis, and biological evaluation of novel methyl Selanyl– And thiazolidinedione-based hybrids as potent anticancer inducing apoptosis and cell cycle arrest	13
Kynurenic acid derivatives in treatment for Alzheimer's disease	13
Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors	13
Discovery of structurally diverse diazatricyclododecenes as lysosomotropic autophagy inhibitors	13
Discovery of dual-targeted molecules based on Olaparib and Rigosertib for triple-negative breast cancer with wild-type BRCA	13
Design and synthesis of phenanthridinone and phenanthridine derivatives and their radiosensitizing activity	13
Synthesis and biological evaluation of indoline derivatives as CDGSH iron sulfur domain 2 activators	13
Truxillic acid monoamides as fatty acid binding protein 5 inhibitors	13
Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease	13
Discovery of novel hypoxia-activated, nitroimidazole constructed multi-target kinase inhibitors on the basis of AZD9291 for the treatment of human lung cancer	13
Stereoisomers of cannabidiols and their pharmacological activities – A potentially novel direction for cannabinoids	13
Editorial Board	12
Recent research progress of β-carbolines as privileged scaffold in the discovery of anticancer agent (2019–2024)	12
Editorial Board	12
Synthesis and biophysical properties of tetravalent PEG-conjugated antisense oligonucleotide	12
Graphical abstract TOC	12
Strategic approaches to the discovery of biologically active indole derivatives: a comprehensive review	12
Modulation of aryl hydrocarbon receptor activity by halogenated indoles	12
Scaffold hopping and sidechain modification from a flavone scaffold lead to discovery of potent, selective CK2A2 inhibitors with favorable properties for CNS activity	12

Recent advances on synthesis and biological activities of C-17 aza-heterocycle derived steroids	12
Structure-based lead optimization to improve potency and selectivity of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid series of heparanase-1 inhibitor	12
Peptide-based approaches to quorum-sensing disruption: emerging trends and applications in antimicrobial therapy	12
Structure-activity relationship studies and biological properties evaluation of peptidic NRP-1 ligands: Investigation of N-terminal cysteine importance	12
Discovery of a potent C20-oxime pachysandra alkaloid analogue promising for treatment of hepatocellular carcinoma	12
Editorial Board	12
Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction	12
Editorial Board	12
Biocompatible conjugated polymer nanoparticles labeled with 225Ac for tumor endoradiotherapy	12
Design, synthesis, and biological evaluation of 2-arylamino-4-(piperidin-4-yloxy)pyrimidines as potent EGFRT790M/L858R inhibitors to treat non-small cell lung cancer	11
Corrigendum to “Discovery of novel Quinazoline-based KRAS G12C inhibitors as potential anticancer agents” [Bioorg. Med. Chem. 71 (2022) 116962]	11
Synthesis of 1,8-cineole derivatives and evaluation of their cytoprotective effects against cisplatin-induced HK-2 cell injury	11
Discovery and development of small-molecule heparanase inhibitors	11
Design of a potent and selective dual JAK1/TYK2 inhibitor	11
Synthesis and biological evaluation of 4H-benzo[e][1,3]oxazin-4-ones analogues of TGX-221 as inhibitors of PI3Kβ	11
Graphical abstract TOC	11
Selenoneine-inspired selenohydantoins with glutathione peroxidase-like activity	11
Potential COX-2 inhibitors modulating NF-κB/MAPK signaling pathways: Design, synthesis and evaluation of anti-inflammatory activity of Pterostilbene-carboxylic acid derivatives with an oxime ether moi	11
Graphical abstract TOC	11
Evaluation of potential anticonvulsant fluorinated N-benzamide enaminones as T-type Ca2+ channel blockers	11
Discovery and optimization of anthraquinone derivatives containing substituted bisbenzyloxy groups as a novel scaffold damaged endoplasmic reticulum and against hepatocellular carcinoma cells	11
Editorial Board	11
Thiazolidinedione-based structure modification of ergosterol peroxide provides thiazolidinedione-conjugated derivatives as potent agents against breast cancer cells through a PI3K/AKT/mTOR pathway	11
Design, synthesis and anti-tumor efficacy of novel phenyl thiazole/triazole derivatives as selective TrkA inhibitors	11
Graphical abstract TOC	11
Design, synthesis, and pharmacological evaluation of N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as interleukin-1 receptor-associated kinase 4 inhibitors with reduced potenti	11
Rational design of AIEgens through π-bridge engineering for dual-modal photodynamic and photothermal therapy	11
Design, synthesis, and evaluation of antipyrine and nicotinic acid derivatives as anti-inflammatory agents: in vitro and in vivo studies	11
Structure-based design of a novel series of cholesterol 24-hydroxylase (CH24H) inhibitors bearing 1,3-oxazole as a heme–iron binding group	11
Synthesis and characterization of new acid-functionalized porphyrins displaying antimicrobial activity against gram positive bacteria, yeasts and filamentous fungi with or without ultra-high irradianc	11
Target discovery of bioactive natural products with native-compound-coupled CNBr-activated Sepharose 4B beads (NCCB): Applications, mechanisms and outlooks	11
Effect of helicity and hydrophobicity on cell-penetrating ability of arginine-rich peptides	10
Structure activity relationships leading to the identification of the indirect activator of AMPK, R419	10
Synthesis and antimicrobial studies of cadasides analogues via on-resin esterification	10
Natural scaffold, modern strategy: Coumarin hybrids as potential carbohydrate-digesting enzyme inhibitors-A decade of medicinal chemistry exploration (2015–2025)	10
Synthesis of 6-ethoxyphenyl 4-fluorobenzenesulfonate-tagged thiosemicarbazones as carbonic anhydrase inhibitors: In-vitro and in silico approach	10
Discovery and biological evaluation of novel dual PTP1B and ACP1 inhibitors for the treatment of insulin resistance	10
Graphical abstract TOC	10
Graphical Abstract TOC	10
Corylin induces UGT1A1 via PPARs/AhR and exerts hepatoprotection in mice	10
The most common linkers in bioactive molecules and their bioisosteric replacement network	10
Elongation of N6-benzyladenosine scaffold via Pd-catalyzed C–C bond formation leads to derivatives with antiflaviviral activity	10
A special issue on artificial intelligence for drug discovery	10
Graphical abstract TOC	10
Inhibition of the hERG potassium ion channel by different non-nucleoside human cytomegalovirus polymerase antiviral inhibitor series and the exploration of variations on a pyrroloquinoline core to red	10
Tenuistones A–H, novel flavonoid derivatives from Miliusa tenuistipitata with anti-proliferative and anti-migration activities against triple-negative breast cancer cells	10
Discovery of evodiamine derivatives as potent insecticide candidates	10
Exploration of 1,2,3-triazole linked benzenesulfonamide derivatives as isoform selective inhibitors of human carbonic anhydrase	10
Discovery and characterization of a high-affinity G-quadruplex binding peptide via mRNA display	9
Engineered B7-H3-targeted VHH-Fc fusion antibody demonstrates rapid tumor accumulation for infrared imaging in pancreatic cancer xenograft model	9
Graphical abstract TOC	9
Advances of HDAC dual inhibitors in breast cancer treatment	9
Silybins are stereospecific regulators of the 20S proteasome	9
Design, synthesis and anti-rheumatoid arthritis activity of target TLR4 inhibitors	9
Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue	9
Editorial Board	9
Discovery, Topo I inhibitory activity and mechanism evaluation of two novel cytisine-type alkaloid dimers from the seeds of Sophora alopecuroides L	9
Design, classification, and adverse effects of NSAIDs: A review on recent advancements	9
RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA	9
Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors	9
Synthesis and biological evaluation of hybrids from optically active ring-opened 3-N-butylphthalide derivatives and 4-fluro-edaravone as potential anti-acute ischemic stroke agents	9
Discovery of acetohydroxyacid synthase inhibitors as anti-tuberculosis lead compounds from natural products	9
Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe disease	9
Targeting the PI3K/mTOR pathway in idiopathic pulmonary fibrosis: Advances and therapeutic potential	9
Transcript and temporal-specific RNA nucleotide editing technologies	9
Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents	9
Recent achievements in molecular insights, anticancer activities, and comparative structure activity relationships of thiazolidin-4-one derivatives as EGFR inhibitors (2019-present)	9
Unveiling the power of quinazoline derivatives: a new frontier in targeted cancer therapy	9
Design, synthesis, and biological evaluation of a potential long-acting glucagon-like peptide-1 (GLP-1) analog	9
Exogenous/endogenous stimuli-responsive antitumor prodrugs advance precision chemotherapy	9
Editorial Board	9
Drug discovery targeting protein arginine methyltransferase 5 (PRMT5): an update	9
Design, synthesis, and bioactivity study on Lissodendrins B derivatives as PARP1 inhibitor	9
Advances in the development of Rho GTPase inhibitors	9
A new small molecule DoNA binding to CAG repeat RNA	9
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies	9
Contents continued	9
Synthesis and biological evaluation of sulfonylpyridine derivatives as potential anti-chlamydia agents	9
Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease	9
Editorial Board	9
Histone deacetylase (HDAC) inhibitor specificity determinants are preserved in a class of dual HDAC/non-covalent proteasome inhibitors	9
Virtual screening, synthesis, optimization and anti-inflammatory activity of novel chromones as specific COX-2 inhibitors	9
Saturation transfer difference (STD)-NMR spectroscopy in drug discovery: A comprehensive review on identified potential hits based on natural and synthetic scaffolds against therapeutic drug targets	9
Design, synthesis and biological evaluation of 3-arylisoquinoline derivatives as topoisomerase IIα inhibitors for the therapy of small cell lung cancer	9
Contents continued	9
New phenylpiperazine-thiazolidine-2,4-dione hybrids targeting MAO inhibition: Synthesis, biological evaluation, kinetic study and in silico insights	9
Editorial Board	9
A critical update on the strategies towards small molecule inhibitors targeting Serine/arginine-rich (SR) proteins and Serine/arginine-rich proteins related kinases in alternative splicing	9
Discovery of CN0 as a novel proteolysis-targeting chimera (PROTAC) degrader of PARP1 that can activate the cGAS/STING immunity pathway combined with daunorubicin	9
Glutathione-responsive PROTAC for targeted degradation of ERα in breast cancer cells	9
Graphical abstract TOC	9
Design, in silico study, and efficient synthesis of N-acylhydrazones in deep eutectic solvents: potential anticonvulsant agents	9
Graphical abstract TOC	9
Synthesis and evaluation of sulfonamide derivatives targeting EGFR790M/L858R mutations and ALK rearrangement as anticancer agents	8
Auranofin inhibits virulence pathways in Pseudomonas aeruginosa	8