OOIR: Observatory of International Research

Papers

(The H4-Index of Bioorganic & Medicinal Chemistry is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Synthesis and antiproliferative activity of (−)-cleistenolide, (6S)-cleistenolide and 4-substituted cleistenolide analogues	93
Current Japanese pharmaceutical chemistry	85
Targeting prolidase. A survey of the literature data to depict a structure-activity relationship frame and to address future studies for drug development	82
Synthesis and medicinal chemistry of tetronamides: Promising agrochemicals and antitumoral compounds	67
Synthesis and biological evaluation of pyrazole-fused oleanolic acid derivatives as novel inhibitors of inflammatory and osteoclast differentiation	54
Graphical abstract TOC	52
Contents continued	49
Production and synthesis of a novel 191Pt-labeled platinum complex and evaluation of its biodistribution in healthy mice	48
Crescent-shaped meta-substituted benzene derivatives as a new class of non-nucleoside ribonuclease A inhibitors	43
Selective targeting of human TET1 by cyclic peptide inhibitors: Insights from biochemical profiling	40
Editorial Board	40
Targeting m6A binding protein YTHDFs for cancer therapy	39
RNA-templated chemical synthesis of proapoptotic L- and d-peptides	35
Discovery of trisubstituted meta-carboranes as T cell activators by regulating CD28 cytoplasmic region and SH2 domains of Grb2 and PI3K interactions	34
Design, synthesis, biological activity and molecular docking studies of triazolopyridine derivatives as ASK1 inhibitors	34
Decades old glitazones still find niche in drug discoveries as PPAR-γ agonists: medicinal chemistry perspective, structure-activity relationships and therapeutic implications	33
Development of delivery carriers for plasmid DNA by conjugation of a helical template to oligoarginine	33
Innovative synthesis and purification method of fluorescent and bifunctional substrates for self-labelling protein tags	33
Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation	32
Research progress of STAT3-based dual inhibitors for cancer therapy	31
Graphical abstract TOC	31
Natural product-derived antifungals against Candida albicans: Chemical diversity and mechanisms of action	30
Design, synthesis and evaluation the bioactivities of novel 1,3-dimethyl-6-amino-1H-indazole derivatives as anticancer agents	30
Janus dendritic ionizable lipids with fine designed headgroup and tails to improve mRNA delivery efficiency	28
Discovery of 3-hydroxymethyl-azetidine derivatives as potent polymerase theta inhibitors	28

Sulfadoxine derivatization through multicomponent reactions to obtain new antiplasmodial compounds	28
Multiple approaches to repurposing drugs for neuroblastoma	28
Sustainable electrochemical C(sp3) − H oxygenation using water as the oxygen source	27
Design, synthesis and antibacterial evaluation of oxazolidinone derivatives containing N-methylglycyl or quaternary ammonium salts	27
A pharmacophore-based approach to demonstrating the scope of alcohol dehydrogenases	27
Exploring novel A2AAR antagonists: Design, synthesis, and evaluation of 2,6,9-trisubstituted purine derivatives as promising antifibrotic agents	27
Synthesis, evaluation of anti-breast cancer activity in vitro of ICS II derivatives and summary of the structure-activity relationship	27
Assessing the rigidity of cubanes and bicyclo(1.1.1)pentanes as benzene bioisosteres	27
Current development and structure–activity relationship study of berberine derivatives	27