OOIR: Observatory of International Research

Papers

(The H4-Index of Bioorganic & Medicinal Chemistry is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
A comprehensive review on the biological interest of quinoline and its derivatives	224
A panoramic review of IL-6: Structure, pathophysiological roles and inhibitors	207
Anti-diabetic drugs recent approaches and advancements	113
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors	112
Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes	72
Tetrazoles as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies	66
An insight into the medicinal attributes of berberine derivatives: A review	64
Discovery of novel pyrazolo[3,4-b]pyridine scaffold-based derivatives as potential PIM-1 kinase inhibitors in breast cancer MCF-7 cells	64
Application of marine natural products in drug research	62
Design, synthesis, and anti-proliferative evaluation of new quinazolin-4(3H)-ones as potential VEGFR-2 inhibitors	57
From triazolophthalazines to triazoloquinazolines: A bioisosterism-guided approach toward the identification of novel PCAF inhibitors with potential anticancer activity	52
Pyridine alkaloids with activity in the central nervous system	48
VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents	48
Recent advances on synthesis and biological activities of aurones	48
Chemical reactivity and uses of 1-phenyl-3-methyl-5-pyrazolone (PMP), also known as edaravone	45
[1,2,4]Triazolo[4,3-c]quinazoline and bis([1,2,4]triazolo)[4,3-a:4′,3′-c]quinazoline derived DNA intercalators: Design, synthesis, in silico ADMET profile, molecular docking and anti-proliferative eva	44
Structural modification aimed for improving solubility of lead compounds in early phase drug discovery	43
Antiviral strategies targeting host factors and mechanisms obliging +ssRNA viral pathogens	43
Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies	41
Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs	41
Indole acrylonitriles as potential anti-hyperglycemic agents: Synthesis, α-glucosidase inhibitory activity and molecular docking studies	39
The research progress in and perspective of potential fungicides: Succinate dehydrogenase inhibitors	39
Porphyrin and phthalocyanine photosensitizers designed for targeted photodynamic therapy of colorectal cancer	38
Promising antifungal agents: A minireview	38
Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors	38

Advancements in the development of multi-target directed ligands for the treatment of Alzheimer’s disease	36
Covalent peptides and proteins for therapeutics	36
The natural-based optimization of kojic acid conjugated to different thio-quinazolinones as potential anti-melanogenesis agents with tyrosinase inhibitory activity	35
Exploration of 1,2,3-triazole linked benzenesulfonamide derivatives as isoform selective inhibitors of human carbonic anhydrase	35
Identification of the first noncompetitive SARM1 inhibitors	34
Design, synthesis and molecular docking studies of thymol based 1,2,3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells	33
A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove	31