Trends in Biochemical Sciences

Article	Citations
Advisory Board and Contents	560
Subscription and Copyright Information	259
Subscription and Copyright Information	225
Conserved signaling gears that sustain circadian clock robustness	157
Advisory Board and Contents	152
Adding post-translational modifications and protein–protein interactions to protein schematics	145
Harnessing the power of peptides: advances and collaborations in biochemistry	145
CRISPR/Cas9 boosts wheat yield by reducing brassinosteroid signaling	144
Multiplayer virtual reality for understanding biomolecular structures	130
Engineered protein inhibitors for precise targeting of matrix metalloproteinases	130
Parallels and crosstalk of ADP-ribosylation and ubiquitination	128
Did circular DNA shape the evolution of mammalian genomes?	115
Strengthening the philosophical basis of graduate science education	107
Cap in hand: giant viruses, stolen translation, and a road to endosymbiosis?	102
Intrinsically disordered regions in eukaryotic mRNA decay pathways	93
Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics	91
Novel machine learning approaches revolutionize protein knowledge	89
Understanding peptide hormones: from precursor proteins to bioactive molecules	85
Decoding ceramide function: how localization shapes cellular fate and how to study it	82
Fragment-based drug discovery supports drugging ‘undruggable’ protein–protein interactions	81
Cellular oxidants and the proteostasis network: balance between activation and destruction	80
From lead to market: chemical approaches to transform peptides into therapeutics	80
Subconductance states add complexity to Piezo1 gating model	75
Challenges of biomolecular science education in Africa and the way forward	72
Bacterial transformation	72

Using graphs and charts in scientific figures	71
The transition phase: preparing to launch a laboratory	70
Determining and interpreting protein lifetimes in mammalian tissues	69
Structural diversity of the CE-clan proteases in bacteria to disarm host ubiquitin defenses	66
Activation, decommissioning, and dememorization: enhancers in a life cycle	64
Transcription-coupled nucleosome assembly	60
Mobile peptide and receptor complex mediates systemic stomatal immunity	60
Transcription-coupled global genomic repair in E. coli	58
Transcription factor IID parks and drives preinitiation complexes at sharp or broad promoters	57
Glucokinase: from allosteric glucose sensing to disease variants	57
Microtubule nucleation for spindle assembly: one molecule at a time	56
Small RNA and Toll-like receptor interactions: origins and disease mechanisms	55
Exploring membrane asymmetry and its effects on membrane proteins	54
Diverse heterochromatin states restricting cell identity and reprogramming	54
Mitochondrial dynamics and pore formation in regulated cell death pathways	53
Proteasome-derived peptides: separating the trash from the recycling	53
Cotranslational sorting and processing of newly synthesized proteins in eukaryotes	52
Biochemistry at scale: Seeing both the forest and the trees	51
Orthogonal regulation of protein abundance	51
Autophagy regulation by phase separation, avidity, and wetting	48
The HIF axes in cancer: angiogenesis, metabolism, and immune-modulation	48
Subscription and Copyright Information	47
Creative approaches using proximity labeling to gain new biological insights	47
A metabolon channels nicotine biosynthesis	47
Pyruvylation: a link bridging metabolic disorders and impaired antiviral immunity	46
Advisory Board and Contents	44
A plant immune protein fights against cancer	43
Engineering RiPP pathways: strategies for generating complex bioactive peptides	43
Making nucleic acid structures and schematics	42
The RNA tether model for human chromosomal translocation fragile zones	42
Thiol dioxygenases: from structures to functions	42
Advisory Board and Contents	42
Making ends meet: a universal driver of large ribosomal subunit biogenesis	42
An outreach activity to enhance biochemistry pedagogy	41
Two hearts beat as one: the debate over RAS dimers continues	40
The metabolic code of ferroptosis: nutritional regulators of cell death	39
Tandem repeats matter for the functional versatility of giant proteins	39
Control of chloroplast degradation and cell death in response to stress	39
Adenosine signals an imbalance between activity and supply in privileged cells	39
Just bypass it: mechanisms of DNA damage tolerance	38
Structural insights into membrane adenylyl cyclases, initiators of cAMP signaling	37
Mitochondrial tRNA processing: a neutral evolutionary ratchet innovation	37
Functional modulation of chemical mediators in microbial communities	37
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Innovations in the electron transport chain fuel archaeal methane metabolism	36
Balancing act: lipid-to-protein ratios steer the aggregation fate of α-synuclein	36
The expanding landscape of canonical and non-canonical protein phosphorylation	36
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Double-duty isomerases: a case study of isomerization-coupled enzymatic catalysis	35
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Metamorphic protein folding as evolutionary adaptation	34
Liquid–liquid phase separation in presynaptic nerve terminals	34
Rethinking transcription factor dynamics and transcription regulation in eukaryotes	34
Zn2+ transients and signaling in mammalian systems	34
Molecular regulation of the salicylic acid hormone pathway in plants under changing environmental conditions	34
Non-histone binding functions of PHD fingers	33
Subscription and Copyright Information	33
Decoding disease-relevant variants with base and prime editors at scale	33
TiBS at 50	32
Advisory Board and Contents	32
Advisory Board and Contents	32
Journey to the past: molecular de-extinction enables the discovery of ancient β-defensins and highlights their evolutionary history	31
Multifaceted control of T cell differentiation by STIM1	31
CryoEM shows the active dynein complex on microtubules	30
Does chromatin function as a metabolite reservoir?	29
Orange carotenoid proteins: structural understanding of evolution and function	29
Forging a path toward a more sustainable laboratory	29
Cooperative assembly of the mitochondrial respiratory chain	29
Programmable protein editing	29
Functional insights into the nitrogenase-like enzyme superfamily	28
The crosstalk of m6A-modified RNA with DNA damage repair	28
Proteostasis in cellular dormancy: lessons from yeast to oocytes	28
The rapamycin sTORy: 50-year journey from Easter Island to the frontiers of biology and medicine	28
Recent advances in enzymes active on lignin-derived aromatic compounds	28
Time-resolved serial crystallography to reveal protein structural changes	28
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Advances, challenges, and opportunities in structural biology	27
Advisory Board and Contents	27
Advisory Board and Contents	26
Drugging the proteome via large-scale chemoproteomics	25
Advances in understanding aryl hydrocarbon receptor structure, function, and modulation	25
Powerful polymerases synthesize labeled RNA better, faster, stronger	25
PhD journey	25
Monitoring subcellular NADP redox state with NAPstar biosensors	25
Computationally guided AAV engineering for enhanced gene delivery	24
Advancing nanopore technology toward protein identification and sequencing	24
TRAPs: the ‘elevator-with-an-operator’ mechanism	24
Advisory Board and Contents	23
Structural mechanisms of mitochondrial uncoupling protein 1 regulation in thermogenesis	23
FN3K: the (un)sweetest kinase	23
E3 ubiquitin ligases in signaling, disease, and therapeutics	23
Decoding anaphylatoxins: unveiling the molecular mechanisms of complement receptor activation and signaling	23
How to compile different types of structural visualizations in one panel	22
Protein SUMOylation and phase separation: partners in stress?	22
Ligand-independent receptor clustering modulates transmembrane signaling: a new paradigm	22
SRC homology 3 domains: multifaceted binding modules	22
PTMs as molecular encoders: reprogramming chaperones into epichaperomes for network control in disease	22
Wrapping up a special series on scientific figure development	22
Endogenous plant nitroxyl, a new component of nitric oxide biology	22
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Synaptoneurolipidomics: lipidomics in the study of synaptic function	21
Oxytocin and vasopressin signaling in health and disease	21
Voices across Asia and Oceania: Biochemistry across borders	21
Advisory Board and Contents	20
To Ub or not to Ub: a regulatory question in TGF-β signaling	20
SLiM-binding pockets: an attractive target for broad-spectrum antivirals	20
Discordant skeletal muscle gene and protein responses to exercise	20
Discovering riboswitches: the past and the future	20
Enlightening epigenetics: optochemical tools illuminate the path	19
Spray-type modifications: an emerging paradigm in post-translational modifications	19
Protein Termini 2022: central roles of protein ends	19
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The past, present, and future of RNA biochemistry and mitochondrial research	18
Cytoplasmic gene expression: lessons from poxviruses	18
The CENP-A nucleosome: where and when it happens during the inner kinetochore’s assembly	18
Maximizing grant funding: strategies for negotiating laboratory pricing	18
Structural transitions modulate the chaperone activities of Grp94	18
Voices across Africa: from local challenges to global impact	18
Regulation of plant NLRs by post-translational modifications	18
Emerging structural insights into PRC2 function in development and disease	18
Biomolecules capturing live bacteria from clinical samples	18
Creating accessibility in academic negotiations	17
Exploring nondegrading molecular glues for protein–protein interactions	17
Mass spectrometry-based single-cell proteomics technologies, trends, and biological insights	17
Oxidative protein folding fidelity and redoxtasis in the endoplasmic reticulum	16
Mitoxyperilysis: fasting-induced cell death in immunometabolism and disease	16
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Subscription and Copyright Information	16
Advisory Board and Contents	16
Thermal proteome profiling of protein-centric interactions and modifications	16

Understanding the dynamic design of the spliceosome	16
Emerging roles and regulatory mechanisms involved in glutamine metabolism	16
Advisory Board and Contents	16