OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Biochemical Sciences is 60. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)

Article	Citations
The AMP-activated protein kinase cascade – a unifying system for energy control	879
TPR proteins: the versatile helix	851
The riboswitch control of bacterial metabolism	435
Rheb fills a GAP between TSC and TOR	365
Distinct monoubiquitin signals in receptor endocytosis	331
SUMO: ligases, isopeptidases and nuclear pores	311
TSC2: filling the GAP in the mTOR signaling pathway	299
NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response?	293
Revealing lncRNA Structures and Interactions by Sequencing-Based Approaches	227
SAM domains: uniform structure, diversity of function	211
The intracellular voyage of cholera toxin: going retro	208
Functional regulation of p73 and p63: development and cancer	208
Lactate: A Metabolic Driver in the Tumour Landscape	179
The Claudins: From Tight Junctions to Biological Systems	178
Cryo-Electron Microscopy Methodology: Current Aspects and Future Directions	140
Interconnection between Metabolism and Cell Cycle in Cancer	134
Historical review: Another 50th anniversary – new periodicities in coiled coils	121
Sharing the SAGA	118
Biophysical and Mechanistic Models for Disease-Causing Protein Variants	116
The small Tim proteins and the twin Cx3C motif	110
Biochemical Aspects of PD-L1 Regulation in Cancer Immunotherapy	110
The Structural Basis of Necroptotic Cell Death Signaling	107
Targeting Metabolic–Redox Circuits for Cancer Therapy	96
Altered function and regulation of cardiac ryanodine receptors in cardiac disease	95
New Binding Sites, New Opportunities for GPCR Drug Discovery	91
Nanoarchitecture Frameworks for Electrochemical miRNA Detection	91
Historical review: Deciphering the genetic code – a personal account	82
Actin Post-translational Modifications: The Cinderella of Cytoskeletal Control	81
Lysosomal Ion Channels as Decoders of Cellular Signals	78
Impact of disease-related mitochondrial mutations on tRNA structure and function	77
The CW domain, a structural module shared amongst vertebrates, vertebrate-infecting parasites and higher plants	77
Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites	76
Nutrient Zinc at the Host–Pathogen Interface	72
The Tumor Suppressor PALB2: Inside Out	72
Nature and Regulation of Protein Folding on the Ribosome	71
Stochasticity of Biological Soft Matter: Emerging Concepts in Intrinsically Disordered Proteins and Biological Phase Separation	71
Function and Evolution of Upstream ORFs in Eukaryotes	68
Bringing Molecular Dynamics Simulation Data into View	64
Emerging Structural Understanding of Amyloid Fibrils by Solid-State NMR	61
Engineering Metalloprotein Functions in Designed and Native Scaffolds	61
Diseases of protein conformation: what do in vitro experiments tell us about in vivo diseases?	60
Ribosome Stoichiometry: From Form to Function	60