OOIR: Observatory of International Research

Papers

(The TQCC of Biometals is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Both biogenic and chemically synthesized metal sulfide nanoparticles induce oxidative stress and enhance lipid accumulation in Rhodococcus opacus	78
Fluorescent superparamagnetic magnetite-silica nanocomposites as carriers of a platinum diimine complex for photodynamic therapy	65
Flavin-dependent enzymatic and photochemical interconversions between phenylarsonic and phenylarsonous acids	60
Changes in morphological traits, anatomical and molecular alterations caused by gamma-rays and zinc oxide nanoparticles in spinach (Spinacia oleracea L.) plant	55
Oral arsenite exposure induces inflammation and apoptosis in pulmonary tissue: acute and chronic evaluation in young and adult mice	47
Investigation of imbalances in essential/toxic metal levels in the blood of laryngeal cancer patients in comparison with controls	45
Timing and method of manganese supplementation effects thermal resilience of Acropora millepora	40
Effect of citrulline seed priming on growth, photosynthesis, redox equilibrium, secondary metabolic enzymes, metal sequestration and nutrient acquisition in sunflower (Helianthus annuus L.) under chro	40
Synthesis, theoretical analysis, and biological properties of a novel tridentate Schiff base palladium (II) complex	39
Unveiling the antifungal mechanisms of CTP, a new copper(II)-theophylline/1,10-phenanthroline complex, on drug-resistant non-albicans Candida species	37
The importance of zinc, copper and manganese and their impact on growth, immunity and fertility of male cattle: a review	36
Multielement determination (essential and potentially toxic elements) in eye shadows exposed to consumption in Brazil using ICP OES	34
Rapid identification of pyoverdines of fluorescent Pseudomonas spp. by UHPLC-IM-MS	34
Effects of short term dietary zinc deficiency and zinc supplementation on nitro-oxidative stress in testes of Wistar rats	32
The Leptospira interrogans proteome’s response to zinc highlights the potential involvement of this metal in translational—machinery and virulence	32
SARS-CoV2 Nsp1 is a metal-dependent DNA and RNA endonuclease	31
The role of lactoferrin in atherosclerosis	31
Iron overload impairs renal function and is associated with vascular calcification in rat aorta	28
Arsenite tolerance and removal potential of the indigenous halophilic bacterium, Halomonas elongata SEK2	27
Protective effects of melatonin on cadmium subcellular distribution, biochemical, and anatomical alterations in Malva parviflora roots	26
Buffer-free CAS assay using a diluted growth medium efficiently detects siderophore production and microbial growth	26
Evaluation of lipid profile, liver function enzymes, and trace elements in Iraqi diabetic nephropathy patients	25
Berberine-loaded iron oxide nanoparticles alleviate cuprizone-induced astrocytic reactivity in a rat model of multiple sclerosis	24
Synthesis, characterization, biological evaluation and molecular docking of a Schiff base ligand and its metal complexes	22
Cadmium toxicity: its’ uptake and retaliation by plant defence system and ja signaling	20

Copper induced augmentation of antibiotic resistance in Acinetobacter baumannii MCC 3114	19
Efficacy of copper blend coatings in reducing SARS-CoV-2 contamination	19
Antifungal potential of the new copper(II)-theophylline/1,10-phenanthroline complex against drug-resistant Candida species	19
Electronic and ring size effects of N-heterocyclic carbenes on the kinetics of ligand substitution reactions and DNA/protein interactions of their palladium(II) complexes	18
Heavy metals in biological samples of cancer patients: a systematic literature review	18
Effect of Ag and Cu additions on antibacterial performance of Fe-based amorphous alloys	17
Adjuvant therapy with zinc supplementation; anti-inflammatory and anti-oxidative role in multiple myeloma patients receiving autologous hematopoietic stem cell transplantation: a randomized controlled	17
Meta-analysis reveals a core iron-responsive gene signature in Mycobacterium tuberculosis linking siderophore biosynthesis, virulence, and metabolic adaptation	16
Targeting Trypanosoma cruzi with silver and gold-based N-heterocyclic carbene complexes: insights into parasite death and trypanothione reductase interaction	16
Synthesis of biologically active cefpodoxime and vanillin-based schiff base metal complexes with the detailed biological evaluations	15
Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus	15
Co-exposure to arsenic and nickel induces oxidative stress and mineral imbalance, impairing male reproductive parameters in Wistar rats	14
Lactoferrin affects in vitro and in vivo fertilization and implantation in rats	14
Trace elements and metal nanoparticles: mechanistic approaches to mitigating chemotherapy-induced toxicity—a review of literature evidence	14
Copper/zinc ratio and erythrocyte superoxide dismutase in patients with thyroid nodules	14
Protective effect of magnesium on indomethacin-induced gastric ulcer in mice	13
Magnesium, selenium and zinc deficiency compromises antioxidant defense in women with obesity	13
Copper-flavonoid family of complexes involved in alkaline phosphatase activation	13
Metallic nanoparticles: a promising novel therapeutic tool against antimicrobial resistance and spread of superbugs	13
Correction: Lactoferrin affects in vitro and in vivo fertilization and implantation in rats	13
Platinum accumulation in chemotherapy: toxicity mechanisms, challenges, and mitigation strategies	13
Synthesis, theoretical studies, antibacterial, and antibiofilm activities of novel azo-azomethine chelates against the pathogenic bacterium Proteus mirabilis	12
Concentrations of the serum long-chain omega-3 polyunsaturated fatty acids and hair mercury in men in different apolipoprotein E phenotypes	12
Cadmium induces microcytosis and anisocytosis without anaemia in hypertensive rats	12
Metals in seston from Cabo Frio Bay, a region under the influence of upwelling in SE–Brazil	12
Hexavalent chromium induced bioaccumulation, oxidative responses and histological anomalies in freshwater carp Labeo rohita (Hamilton, 1822)	12
Detection of Caco-2 cell absorption rate of Bombyx mori peptide chelated zinc and validation of anti-inflammatory activity based on network pharmacology	12
Bone antiresorptives as potential chelators for iron overload diseases	12
Application of biogas slurry abate Pb metal uptake and oxidative stress in maize (Zea mays L.) by modulating seedling emergence, antioxidant defense, and root structural–functional traits	12
Selenium-biofortified Gboma (Solanum macrocarpon L.) vegetable-supplemented diets increased circulating selenium levels and potentiated endogenous anti-inflammatory, antioxidant and immunomodulatory p	12
Novel method of removing metals from estuarine water using whole microbial mats	12
DFT and TD-DFT studies of free and iron(III)-coordinated vibrioferrin	12
Synthesis, characterization, and bioactivity of Cu(II), Fe(II), Co(II), Ni(II), and Mn(II) complexes with benzilmonoximethiocarbohydrazide-O-methoxybenzaldehyde: experimental and computational insight	12
Feasibility study on Ti-15Mo-7Cu with low elastic modulus and high antibacterial property	11
Reductions in plasma and urine mercury concentrations following N,N′bis-(2-mercaptoethyl) isophthalamide (NBMI) therapy: a post hoc analysis of data from a randomized human clinical trial	11
Amino acid-modified nano-magnetite boosts okra [Abelmoschus esculentus (L.) Moench] yield and iron enrichment for improved nutrition	11
Nano-enabled strategies for iron deficiency and iron deficiency anemia: iron-based nanoparticles for supplementation, bioavailability, and food fortification–a narrative review	11
Cadmium toxicity promotes hormonal imbalance and induces the expression of genes involved in systemic resistances in barley	11
Trace elements and cognitions in elderly population: a case–control study	11
Novel biosynthesized zinc selenite photocatalysts for enhanced degradation of oxytetracycline and Rhodamine B dye with antibacterial activity	11
Vanadium salt inhibits osteoclast formation and preserves bone integrity in a rat model of type-1 diabetes associated bone loss	11
Investigating the phytoavailability of metals in roots of Croton macrostachyus and Phytolacca dodecandra: induced rhizosphere processes	11
Correction: The different affinity of the two metal-binding sites of human ferroportin drives outward directionality of transport	11
Assessment of genotoxicity by the Allium Test of Haplic Chernozem polluted by heavy metals	10
Conjugates of desferrioxamine with 5-aminolevulinic or γ-aminobutyric acid: synthesis, theoretical studies, iron-chelating ability, and penetration in human Caco-2 cells	10
Author Correction: In vitro assessment of antibacterial and antiviral activity of three copper products after 200 rounds of simulated use	10
The role of metals in cancer and the use of metal chelators as a potential treatment strategy	10
Cadmium and copper-induced metabolic and proteomic changes in the root tip during early maize growth	10
A cytotoxic effect of human lactoferrin fusion with Fc domain of IgG	10
Design and preparation of Ti–xFe antibacterial titanium alloys based on micro-area potential difference	10

ICP-OES assessment of trace and toxic elements in Ziziphora clinopodioides Lam. from Iran by chemometric approaches	10
Iron overload induced by ferric derisomaltose and ferric carboxymaltose both increase FGF-23 levels and lead to osteomalacia and bone loss in normal mice	10
Metallic trace elements in marine sponges living in a semi-enclosed tropical lagoon	10
Crosstalk between copper, Alzheimer’s disease, and melatonin	10
Anticancer potential of lactoferrin: effects, drug synergy and molecular interactions	9
Bioaccumulation and nutritional impact of fluoride in Pleurotus ostreatus and Pleurotus djamor with human health risk assessment	9
Unravelling lead-induced toxicity in mammals: the role of oxidative stress and apoptosis and their modulation by emerging therapeutic strategies	9
Lactoferrin, a Great Wall of host-defence?	9
Triorganotin compounds as emerging nuclear retinoid X receptor ligands and their implications in cancer	9
Effects of metal amendment and metalloid supplementation on foliar defences are plant accession-specific in the hyperaccumulator Arabidopsis halleri	9
Structural and functional insights into iron acquisition from lactoferrin and transferrin in Gram-negative bacterial pathogens	8
Antibiotic resistance dissemination in soil ecosystems: deep understanding for effective management and global health protection	8
Functionalization of bacterial microcompartment shell interior with cysteine containing peptides enhances the iron and cobalt loading capacity	8
Cyanobacterial blooms, iron, and environmental pollutants	8
A review of the treatment technologies for hexavalent chromium contaminated water	8
Deciphering the role of human peroxiredoxins for combating lead and zinc mediated cellular toxicity using a yeast model	8
Magnetic nanoparticles in the body parts of Polistes versicolor and Polybia paulista wasps are biomineralized: evidence from magnetization measurements and ferromagnetic resonance spectroscopy	8
A review of mechanisms underlying the protective effects of natural compounds against arsenic-induced neurotoxicity	8
Bovine lactoferrin for the prevention of COVID-19 infection in health care personnel: a double-blinded randomized clinical trial (LF-COVID)	8
Biodegradable Mg–Cu alloy inhibits HBV replication and hepatocellular carcinoma progression	8
Antitumor activity of bovine lactoferrin and its derived peptides against HepG2 liver cancer cells and Jurkat leukemia cells	8
Experimental and computational evaluation of anti-malarial and antioxidant potential of transition metal (II) complexes with tridentate schiff base derived from pyrrolopyrimidine	8
Soil microorganisms enrichment in different rare earth elements enrichment soils around a rare earth tailings pond	8
Abnormal erythrocyte-related parameters in children with Pb, Cr, Cu and Zn exposure	8
Associated effects of blood metal(loid) exposure and impaired glucose metabolism in patients with gastric precancerous lesions or gastric cancer	8
The arylbipyridine platinum (II) complex increases the level of ROS and induces lipid peroxidation in glioblastoma cells	8
Unraveling the molecular mechanisms of aluminium chloride-induced Alzheimer’s disease	8
Investigation of antifungal and antibiofilm activities of green synthesized silver nanoparticles against Candida glabrata	7
Gold nanoparticles incorporating rutin hydrate for targeting oxidative stress-driven neurodegeneration	7
Zinc-regulated growth, chlorophyll, and antioxidant activity drive biofortification in rice varieties	7
Mapping geochemical distribution, toxicity and ecological risk indices of potentially toxic elements in cultured fish and surface water (Blacksea catchment/Türkiye)	7
Higher cadmium and zinc accumulation in parsley (Petroselinum crispum) roots activates its antioxidants defense system	7
Manganese transporters regulate the resumption of replication in hydrogen peroxide-stressed Escherichia coli	7
Synthesis, characterization and biological potential of nitroso-R salt with transition metal complexes	7
Synergistic interaction between lead and cadmium via metal-transporter gene upregulation in mice	7
Evaluation of hydrogel loading with curcumin and silver nanoparticles: biocompatibilities and anti-biofilm activities	7
Translational toxicology of metal(loid) species: linking their bioinorganic chemistry in the bloodstream to organ damage onset	7
Polygonum bistorta Linn. as a green source for synthesis of biocompatible selenium nanoparticles with potent antimicrobial and antioxidant properties	7
Integrative physiological and metabolomic study of Hirschfeldia incana under short- and medium-term lead (Pb) stress	7
Tip60/Kat5 may be a novel candidate histone acetyltransferase for the regulation of liver iron localization via acetylation	7
Haemodialysis alters the serum metal contents in chronic kidney failure patients at hyderabad and adjoining areas	7
Uptake and nuclear translocation of lactoferrin by porcine monocytes: impact of iron binding, protease activity, and monocyte activation	7
Tobacco as an efficient metal accumulator	7
Nitro Substituted Co(II), Ni(II) and Cu(II) Schiff Base Metal complexes: design, spectral analysis, antimicrobial and in-silico molecular docking investigation	7
Surface modification of new innocuous Ti–Mo–Zr based alloys for biomedical applications	7
Urinary metal exposure, systemic inflammation, and advanced cardiovascular-kidney-metabolic syndrome risk in US adults	7
Association of combined exposure to multiple metals with comorbid obesity and myopia in the U.S. population	7
The serum trace metal signature distinguishes patients with psychiatric disorders from healthy controls	7
Recent advances in therapeutic agents for uranium poisoning: a comprehensive review	7