Insect Biochemistry and Molecular Biology

Article	Citations
A single mutation in the mosquito (Aedes aegypti) olfactory receptor 8 causes loss of function to 1-octen-3-ol	59
CLIPA protein pairs function as cofactors for prophenoloxidase activation in Anopheles gambiae	49
BarH1 regulates the expression of conserved odorant-binding protein 22 from Dastarcus helophoroides	45
The mlpt smORF gene is essential for digestive physiology and molting during nymphal stages in the kissing bug Rhodnius prolixus	44
An odorant receptor of the green mirid bug, Apolygus lucorum, tuned to linalool	40
Knockout of the odorant receptor co-receptor, orco, impairs feeding, mating and egg-laying behavior in the fall armyworm Spodoptera frugiperda	36
The allatotropin/orexin system as an example of immunomodulatory properties of neuropeptides	36
Culex quinquefasciatus membrane-bound alkaline phosphatase is a putative receptor for Lysinibacillus sphaericus Tpp49Aa1 toxin	32
Baculovirus infection affects caterpillar chemoperception	30
Relish-mediated C2H2 zinc finger protein IMZF restores Drosophila immune homeostasis via inhibiting the transcription of Imd/Tak1	28
Elevated temperature affects energy metabolism and behavior of bumblebees	24
In vivo RNAi screening identifies multiple deubiquitinases required for the maintenance of intestinal homeostasis in Drosophila	23
Charge substitutions at the voltage-sensing module of domain III enhance actions of site-3 and site-4 toxins on an insect sodium channel	21
Pyrethroid metabolism by eleven Helicoverpa armigera P450s from the CYP6B and CYP9A subfamilies	20
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Characterization of gustatory receptor 7 in the brown planthopper reveals functional versatility	20
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ATP-binding cassette transporter subfamily C members 2, 3 and cadherin protein are susceptibility-determining factors in Bombyx mori for multiple Bacillus thuringiensis Cry1 toxins	19
A deeper insight into the sialome of male and female Ochlerotatus triseriatus mosquitoes	19
The Micrococcus luteus infection activates a novel melanization pathway of cSP10, cSP4, and cSP8 in Helicoverpa armigera	19
Proteomic analysis of pharate pupal molting fluid from the tobacco hornworm, Manduca sexta	18
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In silico promoter analysis and functional validation identify CmZFH, the co-regulator of hypoxia-responsive genes CmScylla and CmLPCAT	18
Regulation of Off-track bidirectional signaling by Semaphorin-1a and Wnt signaling in the Drosophila motor axon guidance	17
Recessive embryonic lethal mutations uncovered in heterozygous condition in silkworm semiconsomic strains	16

A mosquito-specific antennal protein is critical for the attraction to human odor in the malaria vector Anopheles gambiae	16
A highly expressed odorant receptor from the yellow fever mosquito, AaegOR11, responds to (+)- and (−)-fenchone and a phenolic repellent	16
Different myrosinases activate sequestered glucosinolates in larvae and adults of the horseradish flea beetle	16
Differential regulation of the Tor gene homolog drives the red/green pigmentation phenotype in the aphid Myzus persicae	16
Chemosensory proteins as putative semiochemical carriers in the desert isopod Hemilepistus reaumurii	16
Pea aphid odorant-binding protein ApisOBP6 discriminates between aphid sex pheromone components, aphid alarm pheromone and a host plant volatile	15
Binding of de novo synthesized radiolabeled juvenile hormone (JH III) by JH receptors from the Cuban subterranean termite Prorhinotermes simplex and the German cockroach Blattella germanica	15
Sex pheromone receptors of the light brown apple moth, Epiphyas postvittana, support a second major pheromone receptor clade within the Lepidoptera	15
Insights into the structure and composition of mineralized hard cocoons constructed by the oriental moth, Monema (Cnidocampa) flavescens Walker	15
A history of the genetic and molecular identification of genes and their functions controlling insect sex determination	15
fruitless is sex-differentially spliced and is important for the courtship behavior and development of silkmoth Bombyx mori	15
Two venom serpins from the parasitoid wasp Microplitis mediator inhibit the host prophenoloxidase activation and antimicrobial peptide synthesis	15
Involvement of CYP2 and mitochondrial clan P450s of Helicoverpa armigera in xenobiotic metabolism	15
Identification and pharmacological characterization of histamine-gated chloride channels in the fall armyworm, Spodoptera frugiperda	14
The fate of a Solanum steroidal alkaloid toxin in the cabbage looper (Trichoplusia ni)	14
ABC transporter subfamily B1 as a susceptibility determinant of Bombyx mori larvae to Cry1Ba, Cry1Ia and Cry9Da toxins	14
Identification of a vital transcription factor of the alanine aminotransferase in the brown planthopper and its upstream regulatory pathways	14
Serine protease SP7 cleaves prophenoloxidase and is regulated by two serpins in Ostrinia furnacalis melanization	14
Halofuginone triggers a transcriptional program centered on ribosome biogenesis and function in honey bees	14
CRISPR/Cas13a-mediated visual detection: A rapid and robust method for early detection of Nosema bombycis in silkworms	14
Binding characteristics and structural dynamics of two general odorant-binding proteins with plant volatiles in the olfactory recognition of Glyphodes pyloalis	13
Expansion of three types of transposon superfamilies within 25 Mya lead to large genome size of a rice insect pest	13
Factors that regulate expression patterns of insulin-like peptides and their association with physiological and metabolic traits in Drosophila	13
Suppression of the H3K27me3 demethylase disrupts diapause formation in mosquito Culex pipiens	13
Nap1 is essential for eupyrene spermatogenesis and migration in Plutella xylostella	13
Transformer gene regulates feminization under two complementary sex determination loci in the ant, Vollenhovia emeryi	12
Blood meal drives de novo lipogenesis in the fat body of Rhodnius prolixus	12
Aminoacylase efficiently hydrolyses fatty acid amino acid conjugates of Helicoverpa armigera potentially to increase the pool of glutamine	12
Ovariole-specific Yellow-g and Yellow-g2 proteins are required for fecundity and egg chorion rigidity in the red flour beetle, Tribolium castaneum	12
Juvenile hormone regulates reproductive diapause through both canonical and noncanonical pathways in the bean bug Riptortus pedestris	12
Identification and functional analysis of sex-determining genes in the spongy moth, Lymantria dispar (lepidoptera: Erebidae)	12
A conserved asparagine residue stabilizes iron binding in Manduca sexta transferrin-1	12
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Differentially spliced mitochondrial CYP419A1 contributes to ethiprole resistance in Nilaparvata lugens	12
Redundant actions of neuropeptides encoded by the dh-pban gene for larval color pattern formation in the oriental armyworm Mythimna separata	12
Beyond the eye: Kynurenine pathway impairment causes midgut homeostasis dysfunction and survival and reproductive costs in blood-feeding mosquitoes	12
Genome sequencing of a predominant clonal lineage of the grain aphid Sitobion avenae	11
An insight into the female and male Sabethes cyaneus mosquito salivary glands transcriptome	11
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Honeybee queen mandibular pheromone induces a starvation response in Drosophila melanogaster	11
Effect of Triatoma infestans saliva on mouse immune system cells: The role of the pore-forming salivary protein trialysin	11
Increased insulin signaling in the Anopheles stephensi fat body regulates metabolism and enhances the host response to both bacterial challenge and Plasmodium falciparum infection	11
BarH1 regulates odorant-binding proteins expression and olfactory perception of Monochamus alternatus Hope	11
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Mutations in a β-group of solute carrier gene are responsible for egg and eye coloration of the brown egg 4 (b-4) mutant in the silkworm, Bombyx mori	10
Gene expression profiling reveals candidate genes for defining spider silk gland types	10
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Identification of species-specific juvenile hormone response elements in the fall armyworm, Spodoptera frugiperda	10
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Identification and characterization of sexually dimorphic neurons that express the sex-determining gene doublesex in the brain of silkmoth Bombyx mori	10
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Structural insights into the substrate binding of phosphomevalonate kinase from the silkworm, Bombyx mori	10
Functional characterization of putative ecdysone transporters in lepidopteran pests	10
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Atg1 phosphorylation is activated by AMPK and indispensable for autophagy induction in insects	10
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Diverse roles of phosphatidate phosphatases in insect development and metabolism	9
Seminal fluid proteins in the Queensland fruit fly: Tissue origins, effects of mating and comparative genomics	9
Structural characterization and functional analysis of juvenile hormone acid methyltransferase JHAMT3 from the silkworm, Bombyx mori	9
Allocation and metabolism of naturally occurring dietary amino acids in the Oriental hornet	9
Proteomics of purified lamellocytes from Drosophila melanogaster HopT identifies new membrane proteins and networks involved in their functions	9
SYNCAS based CRISPR-Cas9 gene editing in predatory mites, whiteflies and stinkbugs	9
Advances in understanding insect chitin biosynthesis	9
Insights into gene manipulation techniques for Acari functional genomics	9
Evolutionary diversification of insulin-related peptides (IRPs) in aphids and spatiotemporal distribution in Acyrthosiphon pisum	9
Regulation of insulin-like peptide expression in adult Blattella germanica females	9
The molecular mechanisms of insecticide resistance in aphid crop pests	9
Involvement of Methoprene-tolerant and Krüppel homolog 1 in juvenile hormone-signaling regulating the maturation of male accessory glands in the moth Agrotis ipsilon	9
ATP synthase affects lipid metabolism in the kissing bug Rhodnius prolixus beyond its role in energy metabolism	8
Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity	8
Tyraminergic control of vitellogenin production and release in the blood-feeding insect, Rhodnius prolixus	8
Masculinizer is not post-transcriptionally regulated by female-specific piRNAs during sex determination in the Asian corn borer, Ostrinia furnacalis	8
Decapentaplegic retards lipolysis during metamorphosis in Bombyx mori and Drosophila melanogaster	8
Silk of the common clothes moth, Tineola bisselliella, a cosmopolitan pest belonging to the basal ditrysian moth line	8
The role of a novel secretory peptidoglycan recognition protein with antibacterial ability from the Chinese Oak Silkworm Antheraea pernyi in humoral immunity	8
Functional redundancy of the three insulin receptors of cockroaches	8
Lipidome remodeling in aging normal and genetically obese Drosophila males	8
Sestrin regulates acute chill coma recovery in Drosophila melanogaster	8
Knockout of cryptochrome 1 disrupts circadian rhythm and photoperiodic diapause induction in the silkworm, Bombyx mori	8
Masculinizer gene controls male sex determination in the codling moth, Cydia pomonella	8
Pioneering contributors to arthropod cuticle research	7
Decoding the genome of bloodsucking midge Forcipomyia taiwana (Diptera: Ceratopogonidae): Insights into odorant receptor expansion	7
Identification and functional characterization of olfactory indolergic receptors in Drosophila melanogaster	7
PEPCK and glucose metabolism homeostasis in arthropods	7
Mutation in Bombyx mori fibrohexamerin (P25) gene causes reorganization of rough endoplasmic reticulum in posterior silk gland cells and alters morphology of fibroin secretory globules in the silk gla	7
Abundances of transfer RNA modifications and transcriptional levels of tRNA-modifying enzymes are sex-associated in mosquitoes	7
Lipogenesis in Nasonia vitripennis: Influence of sugar chemistry, preferential production of triacylglycerides, and comparison of fatty acid biosynthetic capacity with Drosophila melanogaster	7
The role of OR5, which is highly expressed in the winged grain aphid Sitobion miscanthi, in specific recognition of EBF	7
Time-dependent metabolome and fatty acid profile changes following a high-fat diet exposure in Drosophila melanogaster	7
Comparison of functions of pheromone receptor repertoires in Helicoverpa armigera and Helicoverpa assulta using a Drosophila expression system	7
Chronic exposure to field-realistic doses of imidacloprid resulted in biphasic negative effects on honey bee physiology	7
Identification of salivary proteins of the cowpea aphid Aphis craccivora by transcriptome and LC-MS/MS analyses	7
Time- and temperature-dependent dynamics of prothoracicotropic hormone and ecdysone sensitivity co-regulate pupal diapause in the green-veined white butterfly Pieris napi	7
A flavivirus-inducible gene expression system that modulates broad-spectrum antiviral activity against dengue and Zika viruses	7
Silkworm FoxL21 plays important roles as a regulator of ovarian development in both oogenesis and ovariole development	7
Physiological and transcriptional changes associated with obligate aestivation in the cabbage stem flea beetle (Psylliodes chrysocephala)	7
Transgenic genome editing-derived antiviral therapy to nucleopolyhedrovirus infection in the industrial strain of the silkworm	7
Overexpression of UDP-glucuronosyltransferase and cytochrome P450 enzymes confers resistance to sulfoxaflor in field populations of the aphid, Myzus persicae	6
The immune function of thioester-containing proteins in typical invertebrate disease vectors	6
Common substitution mutation F348Y of acetylcholinesterase gene contributes to organophosphate and carbamate resistance in Cimex lectularius and C. hemipterus	6
The Wnt pathway regulates wing morph determination in Acyrthosiphon pisum	6
dmrt11E ortholog is a crucial factor for oogenesis of the domesticated silkworm, Bombyx mori	6
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Binding properties of olfactory proteins to host volatiles, free fatty acids and cuticular hydrocarbons in the termite Reticulitermes aculabialis	6
A near-complete genome reveals the population evolution of the cotton-melon aphid Aphis gossypii	6
The draft genome of the Asian corn borer yields insights into ecological adaptation of a devastating maize pest	6
Cytokine receptor DOME controls wing disc development in Bombyx mori	6
Metabolic and transcriptomic characterization of summer and winter dormancy in the solitary bee, Osmia lignaria	6
Knockout of two uridine diphosphate-glycosyltransferase genes increases the susceptibility of Spodoptera litura to Bacillus thuringiensis toxins	6
Structural characterization and proteomic profiling of oviposition secretions across three rice planthopper species	6
Bicarbonate, calcium ions, hydrogen peroxide and trypsin modulate activation of Anopheles gambiae sperm motility and protein tyrosine phosphorylation	6
Identification of immunity-related genes distinctly regulated by Manduca sexta Spӓtzle-1/2 and Escherichia coli peptidoglycan	6
Novel ability of diflubenzuron as an inhibitor of mitochondrial function	6
Nutrition regulates the expression of storage proteins in Bombyx mori via insulin-like/FoxO signaling pathway	5
Progress in the characterization of insulin-like peptides in aphids: Immunohistochemical mapping of ILP4	5
Low GSK3β activity is required for insect diapause through responding to ROS/AKT signaling and down-regulation of Smad1/EcR/HR3 cascade	5
Structural and functional comparisons of salivary α-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus	5
Identification of Helicoverpa armigera promoters for biotechnological applications	5
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Systemic and mitochondrial effects of metabolic inflexibility induced by high fat diet in Drosophila melanogaster	5
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Mandibular glands secrete 24-methylenecholesterol into honey bee (Apis mellifera) food jelly	5
CG32803 is the fly homolog of LDAF1 and influences lipid storage in vivo	5
Convergent Aedes and Drosophila CidB interactomes suggest cytoplasmic incompatibility targets are conserved	5
Ammonium transporter AcAmt mutagenesis uncovers reproductive and physiological defects without impacting olfactory responses to ammonia in the malaria vector mosquito Anopheles coluzzii	5
Juvenile hormone as a causal factor for maternal regulation of diapause in a wasp	5
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Disruption of a BTB-ZF transcription factor causes female sterility and melanization in the larval body of the silkworm, Bombyx mori	5

Serine protease homolog pairs CLIPA4-A6, A4-A7Δ, and A4-A12 act as cofactors for proteolytic activation of prophenoloxidase-2 and -7 in Anopheles gambiae	5
An updated catalog of lipocalins of the chagas disease vector Rhodnius prolixus (Hemiptera, Reduviidae)	5
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The venom composition and parthenogenesis mechanism of the parasitoid wasp Microctonus hyperodae, a declining biocontrol agent	5
Doublesex is essential for masculinization but not feminization in Lygus hesperus	5
Lipin modulates lipid metabolism during reproduction in the cabbage beetle	5
The biological role of core 1β1-3galactosyltransferase (T-synthase) in mucin-type O-glycosylation in Silkworm, Bombyx mori	5
dHNF4 regulates lipid homeostasis and oogenesis in Drosophila melanogaster	5
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Diuretic hormone 31 activates two G protein-coupled receptors with differential second messengers for diuresis in Drosophila suzukii	5
Coordinative mediation of the response to alarm pheromones by three odorant binding proteins in the green peach aphid Myzus persicae	4
Characterization of an agmatine N-acetyltransferase from Bactrocera dorsalis that modulates ovary development	4
Dextran sulfate sodium and uracil induce inflammatory effects and disrupt the chitinous peritrophic matrix in the midgut of Tribolium castaneum	4
Characterization of calcium signaling proteins from the fat body of the Colorado Potato Beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae): Implications for diapause and lipid metabolism	4
Phenotypic analyses, protein localization, and bacteriostatic activity of Drosophila melanogaster transferrin-1	4
Juvenile hormone mediates lipid storage in the oocytes of Dipetalogaster maxima	4
Molting-related proteases in the brown planthopper, Nilaparvata lugens	4
A novel target-site mutation (H146Q) outside the ubiquinone binding site of succinate dehydrogenase confers high levels of resistance to cyflumetofen and pyflubumide in Tetranychus urticae	4
Dual SIFamide receptors in Ixodes salivary glands	4
Choline transporter-like protein 2 interacts with chitin synthase 1 and is involved in insect cuticle development	4
Spatio-temporal distribution and genetic background of elastic proteins inside the chitin/chitosan matrix of insects including their functional significance for locomotion	4
A single point mutation in the Bemisia tabaci cytochrome-P450 CYP6CM1 causes enhanced resistance to neonicotinoids	4
Aliens in the CYPome of the black fungus gnat, Bradysia coprophila	4
A knockout screen of genes expressed specifically in Ae. aegypti pupae reveals a critical role for stretchin in mosquito flight	4
The involvement of insulin/ToR signaling pathway in reproductive performance of Rhodnius prolixus	4
Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes	4
Knockouts of positive and negative elements of the circadian clock disrupt photoperiodic diapause induction in the silkworm, Bombyx mori	4
Notch signaling regulates limb regeneration through Hes1 and HeyL in the Chinese mitten crab	4
BmHen1 is essential for eupyrene sperm development in Bombyx mori but PIWI proteins are not	4
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Identification of an aromatic aldehyde synthase involved in indole-3-acetic acid biosynthesis in the galling sawfly (Pontania sp.) and screening of an inhibitor	4
MicroRNA let-7 is required for hormonal regulation of metamorphosis in the silkworm, Bombyx mori	4
Insights into unique features of Drosophila CYP4G enzymes	4
Over-expression in cis of the midgut P450 CYP392A16 contributes to abamectin resistance in Tetranychus urticae	4
CRISPR/Cas9 mutagenesis abolishes odorant-binding protein BdorOBP56f-2 and impairs the perception of methyl eugenol in Bactrocera dorsalis (Hendel)	4
Genome-wide analysis of long non-coding RNAs and their association with wing development in Aphis citricidus (Hemiptera: Aphididae)	4
The short neuropeptide F receptor regulates olfaction-mediated foraging behavior in the oriental fruit fly Bactrocera dorsalis (Hendel)	3
Mosquito odorant receptor sensitive to natural spatial repellents and inhibitory compounds	3
Cis-regulation of the CYP6CS1 gene and its role in mediating cross-resistance in a pymetrozine-resistant strain of Nilaparvata lugens	3
Sage controls silk gland development by regulating Dfd in Bombyx mori	3
Effects of Niemann-Pick type C2 (NPC2) gene transcripts silencing on behavior of Varroa destructor and molecular changes in the putative olfactory gene networks	3
From cellular biochemistry to systems physiology: New insights into insect lipid metabolism	3
Fibroin heavy chain gene replacement with a highly ordered synthetic repeat sequence in Bombyx mori	3
BmNPV p35 regulates apoptosis in Bombyx mori via a novel target of interaction with the BmVDAC2-BmRACK1 complex	3
The powers and perils of bug editing	3
Osmoregulation by sucrose isomerization in the phloem-feeding whitefly Bemisia tabaci involves members of the glycoside hydrolase family 13	3
A haploid diamondback moth (Plutella xylostella L.) genome assembly resolves 31 chromosomes and identifies a diamide resistance mutation	3
Determination of the larval precursor configuration of the Drosophila adult hindgut by G-TRACE analysis	3
Alterations in energy metabolism of Rhodnius prolixus induced by Trypanosoma rangeli infection	3
JAK and STAT5B mediate olfactory response of migratory locusts to their own volatiles	3
T-box transcription factors Dorsocross and optomotor-blind control Drosophila leg patterning in a functionally redundant manner	3
The parasitoid Exorista sorbillans exploits host silkworm encapsulation to build respiratory funnel for survival	3
Insights into the activation mechanism of Bm-CPA: Implications for insect molting regulation	3
The Relish/miR-275/Dredd mediated negative feedback loop is crucial to restoring immune homeostasis of Drosophila Imd pathway	3
Characterization of cuticular proteins in CPR family in the wolf spider, Pardosa pseudoannulata, and the response of one subfamily genes to environmental stresses	3
Metabolomics and transcriptomics of pheromone biosynthesis in an aggressive forest pest Ips typographus	3
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The red egg gene as a novel effective egg color marker for silkworm transgenesis	2
Cleavage activation and functional comparison of Manduca sexta serine protease homologs SPH1a, SPH1b, SPH4, and SPH101 in conjunction with SPH2	2
Crystal structures of PirA and PirB toxins from Photorhabdus akhurstii subsp. akhurstii K-1	2
Single-nucleus sequencing of silkworm larval midgut reveals the immune escape strategy of BmNPV in the midgut during the late stage of infection	2
Juvenile hormone suppresses sensory organ precursor determination to block Drosophila adult abdomen morphogenesis	2
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Metabolomics analysis of larval secretions reveals a caste-driven nutritional shift in a social wasp colony	2
Both LmDicer-1 and two LmDicer-2s participate in siRNA-mediated RNAi pathway and contribute to high gene silencing efficiency in Locusta migratoria	2
Pyruvate kinase is post-translationally regulated by sirtuin 2 in Aedes aegypti mosquitoes	2
From the fat body to the hemolymph: Profiling tick immune and storage proteins through transcriptomics and proteomics	2
Non-molting dwarf (nm-d) as a mutant of Bombyx mori with a defect in purine synthesis	2
Multicopper oxidase-2 mediated cuticle formation: Its contribution to evolution and success of insects as terrestrial organisms	2
Adaptations to haematophagy: Investigations on how male and female Culex quinquefasciatus (Diptera: Culicidae) deal with human complement activation after a blood meal	2
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An optimized artificial blood feeding assay to study tick cuticle biology	2
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MicroRNA miR-8 promotes cell growth of corpus allatum and juvenile hormone biosynthesis independent of insulin/IGF signaling in Drosophila melanogaster	2
Involvement of GOBP2 in the perception of a sex pheromone component in both larval and adult Spodoptera litura revealed using CRISPR/Cas9 mutagenesis	2
A highly conserved plant volatile odorant receptor detects a sex pheromone component of the greater wax moth, Galleria mellonella (Lepidoptera: Pyralidae)	2
Cytoplasmic Hsp70s promote EcR transport into the nucleus by responding to various stimuli	2
Structural and functional characterization of β-cyanoalanine synthase from Tetranychus urticae	2
A mechanistic analysis of bacterial recognition and serine protease cascade initiation in larval hemolymph of Manduca sexta	2
Peritrophins are involved in the defense against Bacillus thuringiensis and nucleopolyhedrovirus formulations in Spodoptera littoralis (Lepidoptera: Noctuidae)	2
Histamine avoidance through three gustatory receptors in Drosophila melanogaster	2
Identification and functional characterization of olfactory indolergic receptors in Musca domestica	2
Krüppel homolog 1 regulates photoperiodic reproductive plasticity in the cabbage beetle Colaphellus bowringi	2
Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster	2
The Ras/MAPK pathway is required for regenerative growth of wing discs in the black cutworm Agrotis ypsilon	2
Histochemistry and transcriptomics of mucins and peritrophic membrane (PM) proteins along the midgut of a beetle with incomplete PM and their complementary function	2