OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Cell Biology is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Lipid Metabolism in Regulation of Macrophage Functions	254
Mitochondrial Fusion: The Machineries In and Out	213
Extracellular vesicles and nanoparticles: emerging complexities	197
Cell cycle on the crossroad of tumorigenesis and cancer therapy	190
p53 and Tumor Suppression: It Takes a Network	179
The heterogeneity of cellular senescence: insights at the single-cell level	117
Lipid Droplet Nucleation	110
Lipid Droplet Contact Sites in Health and Disease	110
Extracellular Vesicle-Associated Proteins in Tissue Repair	106
All Roads Lead to Directional Cell Migration	105
Regulation of ferroptosis by lipid metabolism	105
Cell biology of inflammasome activation	104
Cristae Membrane Dynamics – A Paradigm Change	98
Cellular functions of cGAS-STING signaling	97
Punching Holes in Cellular Membranes: Biology and Evolution of Gasdermins	91
Actin on and around the Nucleus	90
The dark proteome: translation from noncanonical open reading frames	89
Mechanical communication in fibrosis progression	89
Mechanical Regulation of Transcription: Recent Advances	88
The amoeboid state as part of the epithelial-to-mesenchymal transition programme	87
Cardiolipin in Immune Signaling and Cell Death	87
Nucleation, stabilization, and disassembly of branched actin networks	86
Toward a Consensus View of Mammalian Adipocyte Stem and Progenitor Cell Heterogeneity	84
The Ways of Actin: Why Tunneling Nanotubes Are Unique Cell Protrusions	82
Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications	79

DNA single-strand break repair and human genetic disease	78
Balancing ER-Mitochondrial Ca2+ Fluxes in Health and Disease	78
Metabolic Coordination of Cell Fate by α-Ketoglutarate-Dependent Dioxygenases	78
Cell–3D matrix interactions: recent advances and opportunities	74
3D gastruloids: a novel frontier in stem cell-based in vitro modeling of mammalian gastrulation	72
Tau liquid–liquid phase separation in neurodegenerative diseases	72
New Insights into CDK Regulators: Novel Opportunities for Cancer Therapy	71
Expanding the View of IKK: New Substrates and New Biology	70
Peroxisomes as cellular adaptors to metabolic and environmental stress	69
Transsulfuration, minor player or crucial for cysteine homeostasis in cancer	68
Transcription-Coupled DNA Repair: From Mechanism to Human Disorder	68
Phase separation in genome organization across evolution	67
Photoreceptor Discs: Built Like Ectosomes	66
Regulation of gene expression by glycolytic and gluconeogenic enzymes	66
Cyclin E in normal physiology and disease states	65
Dynamic Plasma Membrane Organization: A Complex Symphony	63
Membrane Protein Quality Control Mechanisms in the Endo-Lysosome System	63
Mitotic disassembly and reassembly of nuclear pore complexes	63
CARM1/PRMT4: Making Its Mark beyond Its Function as a Transcriptional Coactivator	62
Cutting, Amplifying, and Aligning Microtubules with Severing Enzymes	62
Non-canonical mTORC1 signaling at the lysosome	61
A novel superfamily of bridge-like lipid transfer proteins	59
The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development	59
LncRNAs in human cancers: signal from noise	59
When Endoplasmic Reticulum Proteostasis Meets the DNA Damage Response	59
Principles of membrane remodeling by dynamic ESCRT-III polymers	56
Circadian regulation of cancer cell and tumor microenvironment crosstalk	55
Translocation of Proteins through a Distorted Lipid Bilayer	55
MYC: a complex problem	52
Phase Separation during Germline Development	51
Quantitative Data Analysis in Single-Molecule Localization Microscopy	49
Sirtuin 6: linking longevity with genome and epigenome stability	49
Connecting the Dots: Linking Caenorhabditis elegans Small RNA Pathways and Germ Granules	49
Human embryonic development: from peri-implantation to gastrulation	49
Primary ciliary signaling: links with the cell cycle	48
Mitochondrial regulation and white adipose tissue homeostasis	47
The ins-and-outs of exosome biogenesis, secretion, and internalization	47
The Warburg effect: a signature of mitochondrial overload	45
Muscle Stem Cell Quiescence: Controlling Stemness by Staying Asleep	45
Chromatin basis of the senescence-associated secretory phenotype	44
Targeting STING to promote antitumor immunity	44
DNA replication: the recombination connection	44
Quality control of protein complex assembly by the ubiquitin–proteasome system	43
Disulfidptosis: disulfide stress–induced cell death	43
Nucleus segmentation: towards automated solutions	43
Chromatin mobility and relocation in DNA repair	43
A long look at short prokaryotic Argonautes	41
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia	40
Insights into peptidylarginine deiminase expression and citrullination pathways	40
The Complex Dance of Organelles during Mitochondrial Division	40

CDK1, the Other ‘Master Regulator’ of Autophagy	39
The Endothelium: An Active Regulator of Lipid and Glucose Homeostasis	39
Targeting ferroptosis to treat colorectal cancer	38
Role of N7-methylguanosine (m7G) in cancer	38
The peroxisome: an up-and-coming organelle in immunometabolism	38
The elegant complexity of mammalian ecto-5′-nucleotidase (CD73)	38
Rigidity transitions in development and disease	37
Roles of YAP/TAZ in ferroptosis	37
Physics of liquid crystals in cell biology	36
Ferroptosis: mechanisms and implications for cancer development and therapy response	36
Differentiation of the tumor microenvironment: are CAFs the Organizer?	35
J-domain protein chaperone circuits in proteostasis and disease	34
Mechanisms of cellular mRNA transcript homeostasis	34
Long Noncoding RNAs in Human Stemness and Differentiation	33
The autophagy–NAD axis in longevity and disease	33
The emergence of the stem cell niche	33
Fueling Cell Invasion through Extracellular Matrix	32
Cohesin: behind dynamic genome topology and gene expression reprogramming	32
The two sides of creatine in cancer	31
Lysosomal quality control: molecular mechanisms and therapeutic implications	31
Emerging roles of intratumor microbiota in cancer metastasis	31
A New Paradigm in Catalase Research	31
Cut loose TIMP-1: an emerging cytokine in inflammation	31
Built to last: lysosome remodeling and repair in health and disease	30
Emerging roles of peroxisomes in viral infections	30
REV7: Jack of many trades	30
Role of GTPases in Driving Mitoribosome Assembly	30
Cellular mechanisms of connexin-based inherited diseases	29
Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells	29
Phenotypic plasticity during metastatic colonization	29
Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity	28
Tight Junction Structure and Function Revisited	28
Agent-based methods facilitate integrative science in cancer	28
Solute carrier transporters: emerging central players in tumour immunotherapy	28
Kinase regulation by liquid–liquid phase separation	28
Mechanical regulation of cell-cycle progression and division	27
Protecting the future: balancing proteostasis for reproduction	27
Deep learning in image-based phenotypic drug discovery	27
REV7 directs DNA repair pathway choice	26
Shared genetic and epigenetic changes link aging and cancer	26
Seipin: harvesting fat and keeping adipocytes healthy	25
Global miRNA to miRNA Interactions: Impacts for miR-21	25
Plasticity of cancer invasion and energy metabolism	25
Regulation of nucleotide metabolism in cancers and immune disorders	25
Stress relief: emerging methods to mitigate dissociation-induced artefacts	25
Pericytes in the disease spotlight	25
Adherens junction: the ensemble of specialized cadherin clusters	25
Mitochondrial DNA Dynamics in Reprogramming to Pluripotency	25
Bidirectional communication in oogenesis: a dynamic conversation in mice and Drosophila	25
Chromatin Tracing: Imaging 3D Genome and Nucleome	24
The enigmatic roles of epithelial gasdermin B: Recent discoveries and controversies	24
Is euchromatin really open in the cell?	24
The Ubiquitin Ligase TRAIP: Double-Edged Sword at the Replisome	24
Interphase microtubules in nuclear organization and genome maintenance	24
Fracture in living tissues	23
Histone Variants and Histone Modifications in Neurogenesis	23
A glitch in the matrix: organ-specific matrisomes in metastatic niches	23
Regulation of the length of neuronal primary cilia and its potential effects on signalling	23
Protein Sorting within Chloroplasts	23
The web of death: the expanding complexity of necroptotic signaling	22
Spatial regulation of microtubule-dependent transport by septin GTPases	22
Primordial super-enhancers: heat shock-induced chromatin organization in yeast	22
Ferroptosis in mitochondrial cardiomyopathy	22
Caspase-2 as a master regulator of genomic stability	22
Capturing cancer evolution using genetically engineered mouse models (GEMMs)	22