OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Cell Biology is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Advisory Board and Contents	501
Understanding human embryogenesis by building programmable stem cell-based models	368
An ATM D-compartmentalization in DNA damage response	300
HELLS: the transcriptional sentinel	289
Unlocking Latin America´s scientific potential: challenges and opportunities in a globalized world	230
Translation is an emerging constraint on protein homeostasis in ageing	219
The postdoctoral blueprint part one: creating a niche	215
Modulating cell-free DNA biology as the next frontier in liquid biopsies	175
Plasticity of cancer invasion and energy metabolism	170
DNA-PKcs kinase activity orchestrates both end-processing and end-ligation	163
Centrosomes and cancer: balancing tumor-promoting and inhibitory roles	157
(Alternative) transcription start sites as regulators of RNA processing	156
The bidirectional relationship between metabolism and cell cycle control	150
Subscription and Copyright Information	148
Olfaction: an emerging regulator of longevity and metabolism	145
Advisory Board and Contents	136
Subscription and Copyright Information	127
Where protein structure and cell diversity meet	118
What makes genes burst	111
The multifaceted mitochondrial OXA insertase	109
Optical tweezers across scales in cell biology	108
Bucket lists must be completed during cell death	106
A glitch in the matrix: organ-specific matrisomes in metastatic niches	106
Primary ciliary signaling: links with the cell cycle	106
Membrane curvature at the ER–PM contact sites	106

Regulation of lipid droplet dynamics and lipid homeostasis by hydroxysteroid dehydrogenase proteins	99
Opportunities and challenges for deep learning in cell dynamics research	98
Cytoplasmic mtDNA clearance suppresses inflammatory immune responses	96
Lessons in longevity from blood stem cells under protein stress	86
Optimality as a framework for understanding developmental robustness	84
The promiscuous ribosomal P-stalk: a new functional portrait	83
POGK is a domesticated KRAB domain-containing transposable element with tumor suppressive functions in breast cancer	81
DDX47 untangles R-loops with only certain other helicases	77
Progress and limitations in engineering cellular adhesion for research and therapeutics	77
tRNA modifications: insights into their role in human cancers	76
Subscription and Copyright Information	76
Sublethal engagement of apoptotic pathways in residual cancer	76
Cultured meat: creative solutions for a cell biological problem	75
The emergence of the stem cell niche	74
Deciphering the significance of p53 mutant proteins	74
Bioelectric regulation of intestinal stem cells	74
Diverse routes to mitophagy governed by ubiquitylation and mitochondrial import	72
Multifaceted mitochondrial quality control in brown adipose tissue	72
Visualizing intracellular target antigens in live cells	71
Advisory Board and Contents	71
Moonlighting translation factors: multifunctionality drives diverse gene regulation	70
Reimagining journal clubs for inclusive scientific training	70
Reprogramming transcription after DNA damage: recognition, response, repair, and restart	69
Self-inflicted DNA breaks in cell differentiation and cancer	69
Biomolecular condensates: hubs of Hippo-YAP/TAZ signaling in cancer	66
Mitochondrial transfer at the crossroads of cancer, stromal, and immune cells	65
Accessible high-speed image-activated cell sorting	64
Shared genetic and epigenetic changes link aging and cancer	64
Built to last: lysosome remodeling and repair in health and disease	63
Endoplasmic reticulum (ER) protein degradation by ER-associated degradation and ER-phagy	63
Wnt signalling in cell division: from mechanisms to tissue engineering	63
Tumor–stromal metabolic crosstalk in pancreatic cancer	61
Fun in the sun: ribosomes defend against UV irradiation	60
Advisory Board and Contents	59
Unique architectural features of mammalian mitochondrial protein synthesis	57
Telomere dynamics as mediators of gut microbiota–host interactions	57
Young researchers series #3	56
Advisory Board and Contents	55
ERMCS Ca2+ transmission fuels cell division	55
Filopodia: integrating cellular functions with theoretical models	54
Embryos burn fat in standby	54
Advisory Board and Contents	54
Young researchers series #7	53
Revealing new biology from multiplexed, metal-isotope-tagged, single-cell readouts	52
Young researchers series #3	52
Subscription and Copyright Information	52
Targeting SHP1 and SHP2 to suppress tumors and enhance immunosurveillance	50
Thermoporter: a new regulatory mechanism for mitochondrial calcium uniporter activity	50
Membrane remodeling and trafficking piloted by SARS-CoV-2	49
Meiotic spindle pushed outward by inward organelle packing	49

Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia	49
Mechanical communication in fibrosis progression	48
Transcription-coupled repair of DNA–protein crosslinks	48
Intravital and high-content multiplex imaging of the immune system	47
Differentiation of the tumor microenvironment: are CAFs the Organizer?	47
Advisory Board and Contents	46
Advisory Board and Contents	46
Chaperone networks are shaped by cellular differentiation and identity	45
Modulation of membrane–cytoskeleton interactions: ezrin as key player	44
Putative homeostatic role of cancer driver mutations	43
Order from chaos: cellular asymmetries explained with modelling	42
Subscription and Copyright Information	42
Orientational cell adhesions (OCAs) for tissue morphogenesis	42
Oxidative DNA damage and repair at non-coding regulatory regions	40
Phase separation on microtubules: from droplet formation to cellular function?	40
The idiosyncrasies of oocytes	40
ER: a critical hub for STING signaling regulation	40
Cell cycle regulation by the ribotoxic stress response	40
Young researchers series #6	38
Cellular mechanics during division of a genomically minimal cell	38
Disruption of lineage integrity as a precursor to breast tumor initiation	38
Increased O-GlcNAcylation connects metabolic to transcriptional reprogramming during pathophysiological cell activation	38
Sugar symphony: glycosylation in cancer metabolism and stemness	37
Bloodhounds chasing the origin of blood cells	37
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases	37
Mechanical regulation of cell-cycle progression and division	37
Patterns in the tapestry of chromatin-bound RB	37
Versatility of gasdermin D beyond pyroptosis	37
The amoeboid state as part of the epithelial-to-mesenchymal transition programme	36
Subscription and Copyright Information	35
Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis	35
Subscription and Copyright Information	35
Regulation of gene expression by glycolytic and gluconeogenic enzymes	35
Immune surveillance of senescence: potential application to age-related diseases	35
New job for an old tool: PI3Kβ phosphorylates OGT to regulate acetyl-CoA in glioblastoma	34
Subscription and Copyright Information	33
Hidden protein functions and what they may teach us	33
The neuronal-like behaviour of macrophages	33
Advisory Board and Contents	33
Advisory Board and Contents	33
Subscription and Copyright Information	32
Death by ribosome	31
The peroxisome: an up-and-coming organelle in immunometabolism	31
Creating inclusive environments in cell biology by casual mentoring	31
Spatiotemporal dynamic regulation of membraneless organelles by chaperone networks	31
The adipocyte supersystem of insulin and cAMP signaling	31
Spermidine – an old molecule with a new age-defying immune function	30
Extracellular vesicle-mediated crosstalk in tumor microenvironment dominates tumor fate	29
The many faces of H3.3 in regulating chromatin in embryonic stem cells and beyond	29
Young researchers series #2	29
CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division	29
The epigenetic landscape of mesenchymal stem cell and extracellular vesicle therapy	29
Advisory Board and Contents	29
Changing the culture for the future: time to take brain drain in academics seriously	29
Muscle is a stage, and cells and factors are merely players	28
Stress-induced cell depolarization through the MAP kinase–Cdc42 axis	28
ER remodeling via lipid metabolism	27
The Cys/N-degron pathway in the ubiquitin–proteasome system and autophagy	27
The ubiquitin–proteasome system links NADPH metabolism to ferroptosis	27
Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications	27
Quality control of mitochondrial nucleoids	27
Regulated circRNA nuclear export in neuronal differentiation	26
Advisory Board and Contents	26
Subscription and Copyright Information	26
Tumor-initiating cells establish a niche to overcome isolation stress	25
Advisory Board and Contents	25
Advisory Board and Contents	25
Metabolic regulation of mRNA splicing	25