Trends in Cell Biology

Article	Citations
An ATM D-compartmentalization in DNA damage response	353
The postdoctoral blueprint part one: creating a niche	243
Modulating cell-free DNA biology as the next frontier in liquid biopsies	226
Advisory Board and Contents	190
Translation is an emerging constraint on protein homeostasis in ageing	170
HELLS: the transcriptional sentinel	144
DNA-PKcs kinase activity orchestrates both end-processing and end-ligation	133
(Alternative) transcription start sites as regulators of RNA processing	128
Coordination between Transport and Local Translation in Neurons	127
Centrosomes and cancer: balancing tumor-promoting and inhibitory roles	123
Plasticity of cancer invasion and energy metabolism	121
WNT-Regulated Transcriptional Enhancers and Stem Cell Plasticity	117
The bidirectional relationship between metabolism and cell cycle control	116
Subscription and Copyright Information	112
Subscription and Copyright Information	111
Advisory Board and Contents	109
Regulation of lipid droplet dynamics and lipid homeostasis by hydroxysteroid dehydrogenase proteins	103
Bucket lists must be completed during cell death	103
Where protein structure and cell diversity meet	102
Olfaction: an emerging regulator of longevity and metabolism	102
Optical tweezers across scales in cell biology	100
Opportunities and challenges for deep learning in cell dynamics research	99
The multifaceted mitochondrial OXA insertase	95
Cytoplasmic mtDNA clearance suppresses inflammatory immune responses	93
Primary ciliary signaling: links with the cell cycle	90

New Insights into CDK Regulators: Novel Opportunities for Cancer Therapy	88
A glitch in the matrix: organ-specific matrisomes in metastatic niches	86
Subscription and Copyright Information	86
Diverse routes to mitophagy governed by ubiquitylation and mitochondrial import	85
Sublethal engagement of apoptotic pathways in residual cancer	84
Interphase microtubules in nuclear organization and genome maintenance	82
Muscle Stem Cell Quiescence: Controlling Stemness by Staying Asleep	79
Deciphering the significance of p53 mutant proteins	76
Multifaceted mitochondrial quality control in brown adipose tissue	76
DDX47 untangles R-loops with only certain other helicases	74
POGK is a domesticated KRAB domain-containing transposable element with tumor suppressive functions in breast cancer	73
Progress and limitations in engineering cellular adhesion for research and therapeutics	71
Cultured meat: creative solutions for a cell biological problem	69
The emergence of the stem cell niche	68
Bioelectric regulation of intestinal stem cells	66
tRNA modifications: insights into their role in human cancers	66
Advisory Board and Contents	65
Reimagining journal clubs for inclusive scientific training	64
Moonlighting translation factors: multifunctionality drives diverse gene regulation	63
Visualizing intracellular target antigens in live cells	63
Subscription and Copyright Information	63
Accessible high-speed image-activated cell sorting	61
mRNA Transport and Local Translation in Glia	61
Endoplasmic reticulum (ER) protein degradation by ER-associated degradation and ER-phagy	61
Biomolecular condensates: hubs of Hippo-YAP/TAZ signaling in cancer	58
Built to last: lysosome remodeling and repair in health and disease	54
Shared genetic and epigenetic changes link aging and cancer	54
Wnt signalling in cell division: from mechanisms to tissue engineering	54
Reprogramming transcription after DNA damage: recognition, response, repair, and restart	54
Unique architectural features of mammalian mitochondrial protein synthesis	53
Subscription and Copyright Information	53
Advisory Board and Contents	53
Self-inflicted DNA breaks in cell differentiation and cancer	53
Revealing new biology from multiplexed, metal-isotope-tagged, single-cell readouts	53
Young researchers series #3	52
Targeting SHP1 and SHP2 to suppress tumors and enhance immunosurveillance	52
Atherosclerotic Plaque Regression: Experimental Approaches and Therapeutic Advances	52
Young researchers series #3	52
Young researchers series #7	51
ERMCS Ca2+ transmission fuels cell division	49
Advisory Board and Contents	49
Fun in the sun: ribosomes defend against UV irradiation	48
Transcription-coupled repair of DNA–protein crosslinks	47
Meiotic spindle pushed outward by inward organelle packing	47
Filopodia: integrating cellular functions with theoretical models	47
Intravital and high-content multiplex imaging of the immune system	47
Thermoporter: a new regulatory mechanism for mitochondrial calcium uniporter activity	47
Differentiation of the tumor microenvironment: are CAFs the Organizer?	47
Punching Holes in Cellular Membranes: Biology and Evolution of Gasdermins	47
Telomere dynamics as mediators of gut microbiota–host interactions	47

Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia	46
Embryos burn fat in standby	45
Membrane remodeling and trafficking piloted by SARS-CoV-2	43
Mechanical communication in fibrosis progression	43
Principles of membrane remodeling by dynamic ESCRT-III polymers	42
Advisory Board and Contents	41
Putative homeostatic role of cancer driver mutations	41
Oxidative DNA damage and repair at non-coding regulatory regions	41
Advisory Board and Contents	40
Increased O-GlcNAcylation connects metabolic to transcriptional reprogramming during pathophysiological cell activation	40
Subscription and Copyright Information	40
Orientational cell adhesions (OCAs) for tissue morphogenesis	40
Chaperone networks are shaped by cellular differentiation and identity	39
Order from chaos: cellular asymmetries explained with modelling	39
Phase separation on microtubules: from droplet formation to cellular function?	38
The idiosyncrasies of oocytes	38
ER: a critical hub for STING signaling regulation	38
Ubiquitylation at Stressed Replication Forks: Mechanisms and Functions	38
Young researchers series #6	37
Modulation of membrane–cytoskeleton interactions: ezrin as key player	37
Disruption of lineage integrity as a precursor to breast tumor initiation	37
Versatility of gasdermin D beyond pyroptosis	35
Cellular mechanics during division of a genomically minimal cell	35
Sugar symphony: glycosylation in cancer metabolism and stemness	34
Patterns in the tapestry of chromatin-bound RB	33
Mechanical regulation of cell-cycle progression and division	33
Regulation of gene expression by glycolytic and gluconeogenic enzymes	33
Bloodhounds chasing the origin of blood cells	33
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases	32
The amoeboid state as part of the epithelial-to-mesenchymal transition programme	32
Subscription and Copyright Information	31
Advisory Board and Contents	31
Advisory Board and Contents	30
Advisory Board and Contents	30
Subscription and Copyright Information	30
Spatiotemporal dynamic regulation of membraneless organelles by chaperone networks	29
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Hidden protein functions and what they may teach us	29
Creating inclusive environments in cell biology by casual mentoring	29
Death by ribosome	29
Subscription and Copyright Information	29
Extracellular vesicle-mediated crosstalk in tumor microenvironment dominates tumor fate	28
Spermidine – an old molecule with a new age-defying immune function	28
Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis	28
Immune surveillance of senescence: potential application to age-related diseases	27
The adipocyte supersystem of insulin and cAMP signaling	27
New job for an old tool: PI3Kβ phosphorylates OGT to regulate acetyl-CoA in glioblastoma	27
Stress relief: emerging methods to mitigate dissociation-induced artefacts	27
The peroxisome: an up-and-coming organelle in immunometabolism	26
Stress-induced cell depolarization through the MAP kinase–Cdc42 axis	26
Young researchers series #2	26
Redefining actin dynamics of the pointed-end complex in striated muscle	25
Advisory Board and Contents	25
Changing the culture for the future: time to take brain drain in academics seriously	25
Quality control of mitochondrial nucleoids	25
ER remodeling via lipid metabolism	24
Muscle is a stage, and cells and factors are merely players	24
CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division	24
The Cys/N-degron pathway in the ubiquitin–proteasome system and autophagy	24
The many faces of H3.3 in regulating chromatin in embryonic stem cells and beyond	24
Transcription-Coupled DNA Repair: From Mechanism to Human Disorder	24
The ubiquitin–proteasome system links NADPH metabolism to ferroptosis	23
Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications	23
The epigenetic landscape of mesenchymal stem cell and extracellular vesicle therapy	23
Advisory Board and Contents	22
Molecular mechanisms of nucleolar DNA damage checkpoint response	22
Tumor-initiating cells establish a niche to overcome isolation stress	22
Advisory Board and Contents	22
Regulated circRNA nuclear export in neuronal differentiation	21
Chromatin-interacting RNA-binding proteins regulate transcription	21
The state of F-BAR domains as membrane-bound oligomeric platforms	21
Glucose metabolism of TAMs in tumor chemoresistance and metastasis	21
How should we define mammary stem cells?	21
Metabolic regulation of mRNA splicing	21
Phase separation of p62: roles and regulations in autophagy	21
Subscription and Copyright Information	20
Emerging roles of intratumor microbiota in cancer metastasis	20
Subscription and Copyright Information	20
The heterogeneity of cellular senescence: insights at the single-cell level	20
The Warburg effect: a signature of mitochondrial overload	20

3′UTR heterogeneity and cancer progression	20
Advisory Board and Contents	19
Subscription and Copyright Information	19
Technological and computational advances driving high-throughput oncology	19
Regulation of leukemogenesis via redox metabolism	19
TFEB links the cGAS-STING pathway to lysosome biogenesis	19
Subscription and Copyright Information	19
Subscription and Copyright Information	19
Hard to handle: how lipid saturation affects the nuclear envelope	19
A stable start: cotranslational Nt-acetylation promotes proteome stability across kingdoms	19
Chromatin dynamics in human brain development and disease	19
Fracture in living tissues	18
Mechanical Regulation of Transcription: Recent Advances	18
The two sides of creatine in cancer	18
Novel imaging methods and force probes for molecular mechanobiology of cytoskeleton and adhesion	18
Fumarate hydratase as a metabolic regulator of immunity	18
Mechanism-aware and multimodal AI: beyond model-agnostic interpretation	17
DNA single-strand break repair and human genetic disease	17
Multifaceted collagen-DDR1 signaling in cancer	17
Mitotic disassembly and reassembly of nuclear pore complexes	17
The autophagy–NAD axis in longevity and disease	17
Extracellular vesicles from the dead: the final message	17
Subscription and Copyright Information	17
RNA G-quadruplexes and stress: emerging mechanisms and functions	17
Glucagon-producing α-cell transcriptional identity and reprogramming towards insulin production	16
DNA replication: the recombination connection	16
Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations	16
Clonal hematopoiesis and inflammation – the perpetual cycle	16
Nucleus segmentation: towards automated solutions	16
How pervasive are post-translational and -transcriptional modifications?	16
Ferroptosis: mechanisms and implications for cancer development and therapy response	16
Bivalent recognition of histone marks by BARD1	16
Primordial super-enhancers: heat shock-induced chromatin organization in yeast	16
Cyclin E in normal physiology and disease states	16
Elucidating Protein Translocon Dynamics with Single-Molecule Precision	15
Cancer Physical Hallmarks as New Targets for Improved Immunotherapy	15
Advisory Board and Contents	15
The enigmatic roles of epithelial gasdermin B: Recent discoveries and controversies	15
Implementing standardized diversity, equity, and inclusion approaches within scientific communities	15
Spotlighting adult stem cells: advances, pitfalls, and challenges	15
Unfolding by Cdc48/p97: different strokes for different folks	15
Degradation of nuclear components via different autophagy pathways	15
Reflected stemness as a potential driver of the tumour microenvironment	15
Multiplicity of stem cell memories of inflammation and tissue repair in epithelia	14
Extracellular matrix remodeling facilitates obesity-associated cancer progression	14
Mitochondrial substrate oxidation regulates distinct cell differentiation outcomes	14
A novel superfamily of bridge-like lipid transfer proteins	14
Subscription and Copyright Information	14
The role of RAS oncogenes in controlling epithelial mechanics	14
Mechanisms of cellular mRNA transcript homeostasis	14
The initiation of mammalian embryonic transcription: to begin at the beginning	14
Vimentin at the core of wound healing	13
CDK11, a splicing-associated kinase regulating gene expression	13
Experimental evolution for cell biology	13
Coordinated in confined migration: crosstalk between the nucleus and ion channel-mediated mechanosensation	13
MDM4 exon skipping upon dysfunctional ribosome assembly	13
3D genome folding in epigenetic regulation and cellular memory	13
Newly identified cell types crucial for gut commensal tolerance	13
Inter-membrane control of junctional InsP3 receptors by PIP2	13
PYK2, a hub of signaling networks in breast cancer progression	12
Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective	12
Phase separation in genome organization across evolution	12
Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction	12
The cell biology of APOE in the brain	12
miRNA dosage control in development and human disease	12
Roles of YAP/TAZ in ferroptosis	12
Tau liquid–liquid phase separation in neurodegenerative diseases	12
The culture and application of circulating tumor cell-derived organoids	12
Advisory Board and Contents	11
Lysosomal microautophagy: an emerging dimension in mammalian autophagy	11
Central role of the ER proteostasis network in healthy aging	11
Arming a killer: mitochondrial regulation of CD8+ T cell cytotoxicity	11
Plasma membrane damage is a new trigger of cellular senescence	11
REV7: Jack of many trades	10
Metabolic and epigenetic regulation of endoderm differentiation	10
Regulatory landscape of enhancer-mediated transcriptional activation	10
Triple threat: neutrophil ER stress, NETosis, airway inflammation escalation	10
Fueling Cell Invasion through Extracellular Matrix	10
Experimental tools and emerging principles of organellar mechanotransduction	10
Emerging roles of olfactory receptors in glucose metabolism	10
Is clathrin a membrane fission protein?	10
Cell cycle on the crossroad of tumorigenesis and cancer therapy	10
The ins-and-outs of exosome biogenesis, secretion, and internalization	9
Towards solving the mystery of peroxisomal matrix protein import	9
Phenotypic plasticity during metastatic colonization	9
Integrating mechanical signals into cellular identity	9
Subscription and Copyright Information	9
Advisory Board and Contents	8
Advisory Board and Contents	8
Gasdermins gone wild: new roles for GSDMs in regulating cellular homeostasis	8
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Subscription and Copyright Information	8
The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development	8
Advisory Board and Contents	8
The yin and yang of nuclear envelope breakdown through the activity of phosphatase holoenzyme PP2A-B55SUR-6	8